3GF9A

Crystal structure of human intersectin 2 rhogef domain
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
190
structure length
182
Chain Sequence
IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human Intersectin 2 RhoGEF domain
rcsb
molecule tags Endocytosis
source organism Homo sapiens
molecule keywords Intersectin 2
total genus 79
structure length 182
sequence length 190
ec nomenclature
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
A PF14604 SH3_9 Variant SH3 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3gf9A00
3GF9A 3ODWA 1F5XA 2KR9A 2RGNB 2DFKA 4D0OA 4GYVA 2NZ8B 3P6AA 3QBVB 3ODXA 2Z0QA 3EO2A 3MPXA 3KSYA 4D0NB 1KZ7A 1RJ2A 1FOEA 1KZGA 2PZ1A 1XCGA 2DX1A 1KI1B 5FI0A 3KY9A 1BY1A 1XD4A 3JV3A 4MT7A 1LB1A 3BJIA 4GZUA 1X86A 5JHHA 3KZ1A 4YONA 1NTYA 4GOUA 3ODOA 5JHGA 1TXDA 2VRWB 5FI1A 3T06A 1DBHA
chains in the Genus database with same CATH superfamily
3GF9A 3ODWA 1F5XA 2KR9A 2RGNB 2DFKA 4D0OA 4GYVA 2NZ8B 3P6AA 3QBVB 3ODXA 2Z0QA 3EO2A 3MPXA 3KSYA 4D0NB 1KZ7A 1RJ2A 1FOEA 1KZGA 2PZ1A 1XCGA 2DX1A 1KI1B 5FI0A 3KY9A 1BY1A 1XD4A 3JV3A 4MT7A 1LB1A 3BJIA 4GZUA 1X86A 5JHHA 3KZ1A 4YONA 1NTYA 4GOUA 3ODOA 5JHGA 1TXDA 2VRWB 5FI1A 3T06A 1DBHA
chains in the Genus database with same CATH topology
3GF9A 3ODWA 1F5XA 2KR9A 2RGNB 2DFKA 4D0OA 4GYVA 2NZ8B 3P6AA 3QBVB 3ODXA 2Z0QA 3EO2A 3MPXA 3KSYA 4D0NB 1KZ7A 1RJ2A 1FOEA 1KZGA 2PZ1A 1XCGA 2DX1A 1KI1B 5FI0A 3KY9A 1BY1A 1XD4A 3JV3A 4MT7A 1LB1A 3BJIA 4GZUA 1X86A 5JHHA 3KZ1A 4YONA 1NTYA 4GOUA 3ODOA 5JHGA 1TXDA 2VRWB 5FI1A 3T06A 1DBHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GF9 A;  3ODW A;  1F5X A;  2KR9 A;  2RGN B;  2DFK A;  4D0O A;  4GYV A;  2NZ8 B;  3P6A A;  3QBV B;  3ODX A;  2Z0Q A;  3EO2 A;  3MPX A;  3KSY A;  4D0N B;  1KZ7 A;  1RJ2 A;  1FOE A;  1KZG A;  2PZ1 A;  1XCG A;  2DX1 A;  1KI1 B;  5FI0 A;  3KY9 A;  1BY1 A;  1XD4 A;  3JV3 A;  4MT7 A;  1LB1 A;  3BJI A;  4GZU A;  1X86 A;  5JHH A;  3KZ1 A;  4YON A;  1NTY A;  4GOU A;  3ODO A;  5JHG A;  1TXD A;  2VRW B;  5FI1 A;  3T06 A;  1DBH A; 
#chains in the Genus database with same CATH topology
 3GF9 A;  3ODW A;  1F5X A;  2KR9 A;  2RGN B;  2DFK A;  4D0O A;  4GYV A;  2NZ8 B;  3P6A A;  3QBV B;  3ODX A;  2Z0Q A;  3EO2 A;  3MPX A;  3KSY A;  4D0N B;  1KZ7 A;  1RJ2 A;  1FOE A;  1KZG A;  2PZ1 A;  1XCG A;  2DX1 A;  1KI1 B;  5FI0 A;  3KY9 A;  1BY1 A;  1XD4 A;  3JV3 A;  4MT7 A;  1LB1 A;  3BJI A;  4GZU A;  1X86 A;  5JHH A;  3KZ1 A;  4YON A;  1NTY A;  4GOU A;  3ODO A;  5JHG A;  1TXD A;  2VRW B;  5FI1 A;  3T06 A;  1DBH A; 
#chains in the Genus database with same CATH homology
 3GF9 A;  3ODW A;  1F5X A;  2KR9 A;  2RGN B;  2DFK A;  4D0O A;  4GYV A;  2NZ8 B;  3P6A A;  3QBV B;  3ODX A;  2Z0Q A;  3EO2 A;  3MPX A;  3KSY A;  4D0N B;  1KZ7 A;  1RJ2 A;  1FOE A;  1KZG A;  2PZ1 A;  1XCG A;  2DX1 A;  1KI1 B;  5FI0 A;  3KY9 A;  1BY1 A;  1XD4 A;  3JV3 A;  4MT7 A;  1LB1 A;  3BJI A;  4GZU A;  1X86 A;  5JHH A;  3KZ1 A;  4YON A;  1NTY A;  4GOU A;  3ODO A;  5JHG A;  1TXD A;  2VRW B;  5FI1 A;  3T06 A;  1DBH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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