3GF9A

Crystal structure of human intersectin 2 rhogef domain
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
190
structure length
182
Chain Sequence
b'IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Intersectin 2
publication title Crystal structure of human Intersectin 2 RhoGEF domain
rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 79
structure length 182
sequence length 190
ec nomenclature
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
A PF14604 SH3_9 Variant SH3 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3gf9A00
3JV3A 4MT7A 2DFKA 3MPXA 3T06A 4GZUA 1RJ2A 5JHGA 1F5XA 3ODOA 5JHHA 1LB1A 1KZGA 4YONA 2Z0QA 4GOUA 3KZ1A 3GF9A 5FI1A 1XCGA 4D0OA 1BY1A 1DBHA 3QBVB 2VRWB 2PZ1A 1X86A 3KY9A 3ODWA 3BJIA 2NZ8B 1KZ7A 3KSYA 2DX1A 4GYVA 1TXDA 1FOEA 1XD4A 1KI1B 4D0NB 2KR9A 5FI0A 1NTYA 3P6AA 3ODXA 3EO2A 2RGNB
chains in the Genus database with same CATH superfamily
3JV3A 4MT7A 2DFKA 3MPXA 3T06A 4GZUA 1RJ2A 5JHGA 1F5XA 3ODOA 5JHHA 1LB1A 1KZGA 4YONA 2Z0QA 4GOUA 3KZ1A 3GF9A 5FI1A 1XCGA 4D0OA 1BY1A 1DBHA 3QBVB 2VRWB 2PZ1A 1X86A 3KY9A 3ODWA 3BJIA 2NZ8B 1KZ7A 3KSYA 2DX1A 4GYVA 1TXDA 1FOEA 1XD4A 1KI1B 4D0NB 2KR9A 5FI0A 1NTYA 3P6AA 3ODXA 3EO2A 2RGNB
chains in the Genus database with same CATH topology
3JV3A 4MT7A 2DFKA 3MPXA 3T06A 4GZUA 1RJ2A 5JHGA 1F5XA 3ODOA 5JHHA 1LB1A 1KZGA 4YONA 2Z0QA 4GOUA 3KZ1A 3GF9A 5FI1A 1XCGA 4D0OA 1BY1A 1DBHA 3QBVB 2VRWB 2PZ1A 1X86A 3KY9A 3ODWA 3BJIA 2NZ8B 1KZ7A 3KSYA 2DX1A 4GYVA 1TXDA 1FOEA 1XD4A 1KI1B 4D0NB 2KR9A 5FI0A 1NTYA 3P6AA 3ODXA 3EO2A 2RGNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JV3 A;  4MT7 A;  2DFK A;  3MPX A;  3T06 A;  4GZU A;  1RJ2 A;  5JHG A;  1F5X A;  3ODO A;  5JHH A;  1LB1 A;  1KZG A;  4YON A;  2Z0Q A;  4GOU A;  3KZ1 A;  3GF9 A;  5FI1 A;  1XCG A;  4D0O A;  1BY1 A;  1DBH A;  3QBV B;  2VRW B;  2PZ1 A;  1X86 A;  3KY9 A;  3ODW A;  3BJI A;  2NZ8 B;  1KZ7 A;  3KSY A;  2DX1 A;  4GYV A;  1TXD A;  1FOE A;  1XD4 A;  1KI1 B;  4D0N B;  2KR9 A;  5FI0 A;  1NTY A;  3P6A A;  3ODX A;  3EO2 A;  2RGN B; 
#chains in the Genus database with same CATH topology
 3JV3 A;  4MT7 A;  2DFK A;  3MPX A;  3T06 A;  4GZU A;  1RJ2 A;  5JHG A;  1F5X A;  3ODO A;  5JHH A;  1LB1 A;  1KZG A;  4YON A;  2Z0Q A;  4GOU A;  3KZ1 A;  3GF9 A;  5FI1 A;  1XCG A;  4D0O A;  1BY1 A;  1DBH A;  3QBV B;  2VRW B;  2PZ1 A;  1X86 A;  3KY9 A;  3ODW A;  3BJI A;  2NZ8 B;  1KZ7 A;  3KSY A;  2DX1 A;  4GYV A;  1TXD A;  1FOE A;  1XD4 A;  1KI1 B;  4D0N B;  2KR9 A;  5FI0 A;  1NTY A;  3P6A A;  3ODX A;  3EO2 A;  2RGN B; 
#chains in the Genus database with same CATH homology
 3JV3 A;  4MT7 A;  2DFK A;  3MPX A;  3T06 A;  4GZU A;  1RJ2 A;  5JHG A;  1F5X A;  3ODO A;  5JHH A;  1LB1 A;  1KZG A;  4YON A;  2Z0Q A;  4GOU A;  3KZ1 A;  3GF9 A;  5FI1 A;  1XCG A;  4D0O A;  1BY1 A;  1DBH A;  3QBV B;  2VRW B;  2PZ1 A;  1X86 A;  3KY9 A;  3ODW A;  3BJI A;  2NZ8 B;  1KZ7 A;  3KSY A;  2DX1 A;  4GYV A;  1TXD A;  1FOE A;  1XD4 A;  1KI1 B;  4D0N B;  2KR9 A;  5FI0 A;  1NTY A;  3P6A A;  3ODX A;  3EO2 A;  2RGN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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