3GF9A

Crystal structure of human intersectin 2 rhogef domain
Total Genus 79
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
190
structure length
182
Chain Sequence
IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKVQMIGDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Intersectin 2
publication title Crystal structure of human Intersectin 2 RhoGEF domain
rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 79
structure length 182
sequence length 190
ec nomenclature
pdb deposition date 2009-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00621 RhoGEF RhoGEF domain
A PF14604 SH3_9 Variant SH3 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.900.10 Mainly Alpha Up-down Bundle Dbl Homology Domain; Chain A Dbl homology (DH) domain 3gf9A00
4GZUA 1X86A 3MPXA 2KR9A 5JHHA 3EO2A 1DBHA 4D0OA 2VRWB 4GYVA 4GOUA 1KZ7A 2Z0QA 2DFKA 1KZGA 4YONA 2NZ8B 3T06A 5FI1A 1KI1B 3P6AA 3JV3A 3ODOA 3ODXA 3GF9A 2RGNB 4MT7A 3ODWA 3KSYA 1F5XA 1LB1A 3BJIA 1XD4A 1XCGA 1FOEA 1RJ2A 3KZ1A 5FI0A 4D0NB 2PZ1A 3QBVB 1NTYA 5JHGA 1BY1A 3KY9A 1TXDA 2DX1A
chains in the Genus database with same CATH superfamily
4GZUA 1X86A 3MPXA 2KR9A 5JHHA 3EO2A 1DBHA 4D0OA 2VRWB 4GYVA 4GOUA 1KZ7A 2Z0QA 2DFKA 1KZGA 4YONA 2NZ8B 3T06A 5FI1A 1KI1B 3P6AA 3JV3A 3ODOA 3ODXA 3GF9A 2RGNB 4MT7A 3ODWA 3KSYA 1F5XA 1LB1A 3BJIA 1XD4A 1XCGA 1FOEA 1RJ2A 3KZ1A 5FI0A 4D0NB 2PZ1A 3QBVB 1NTYA 5JHGA 1BY1A 3KY9A 1TXDA 2DX1A
chains in the Genus database with same CATH topology
4GZUA 1X86A 3MPXA 2KR9A 5JHHA 3EO2A 1DBHA 4D0OA 2VRWB 4GYVA 4GOUA 1KZ7A 2Z0QA 2DFKA 1KZGA 4YONA 2NZ8B 3T06A 5FI1A 1KI1B 3P6AA 3JV3A 3ODOA 3ODXA 3GF9A 2RGNB 4MT7A 3ODWA 3KSYA 1F5XA 1LB1A 3BJIA 1XD4A 1XCGA 1FOEA 1RJ2A 3KZ1A 5FI0A 4D0NB 2PZ1A 3QBVB 1NTYA 5JHGA 1BY1A 3KY9A 1TXDA 2DX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GZU A;  1X86 A;  3MPX A;  2KR9 A;  5JHH A;  3EO2 A;  1DBH A;  4D0O A;  2VRW B;  4GYV A;  4GOU A;  1KZ7 A;  2Z0Q A;  2DFK A;  1KZG A;  4YON A;  2NZ8 B;  3T06 A;  5FI1 A;  1KI1 B;  3P6A A;  3JV3 A;  3ODO A;  3ODX A;  3GF9 A;  2RGN B;  4MT7 A;  3ODW A;  3KSY A;  1F5X A;  1LB1 A;  3BJI A;  1XD4 A;  1XCG A;  1FOE A;  1RJ2 A;  3KZ1 A;  5FI0 A;  4D0N B;  2PZ1 A;  3QBV B;  1NTY A;  5JHG A;  1BY1 A;  3KY9 A;  1TXD A;  2DX1 A; 
#chains in the Genus database with same CATH topology
 4GZU A;  1X86 A;  3MPX A;  2KR9 A;  5JHH A;  3EO2 A;  1DBH A;  4D0O A;  2VRW B;  4GYV A;  4GOU A;  1KZ7 A;  2Z0Q A;  2DFK A;  1KZG A;  4YON A;  2NZ8 B;  3T06 A;  5FI1 A;  1KI1 B;  3P6A A;  3JV3 A;  3ODO A;  3ODX A;  3GF9 A;  2RGN B;  4MT7 A;  3ODW A;  3KSY A;  1F5X A;  1LB1 A;  3BJI A;  1XD4 A;  1XCG A;  1FOE A;  1RJ2 A;  3KZ1 A;  5FI0 A;  4D0N B;  2PZ1 A;  3QBV B;  1NTY A;  5JHG A;  1BY1 A;  3KY9 A;  1TXD A;  2DX1 A; 
#chains in the Genus database with same CATH homology
 4GZU A;  1X86 A;  3MPX A;  2KR9 A;  5JHH A;  3EO2 A;  1DBH A;  4D0O A;  2VRW B;  4GYV A;  4GOU A;  1KZ7 A;  2Z0Q A;  2DFK A;  1KZG A;  4YON A;  2NZ8 B;  3T06 A;  5FI1 A;  1KI1 B;  3P6A A;  3JV3 A;  3ODO A;  3ODX A;  3GF9 A;  2RGN B;  4MT7 A;  3ODW A;  3KSY A;  1F5X A;  1LB1 A;  3BJI A;  1XD4 A;  1XCG A;  1FOE A;  1RJ2 A;  3KZ1 A;  5FI0 A;  4D0N B;  2PZ1 A;  3QBV B;  1NTY A;  5JHG A;  1BY1 A;  3KY9 A;  1TXD A;  2DX1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...