3GKLC

Following evolutionary paths to high affinity and selectivity protein-protein interactions using colicin7 and immunity proteins
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
82
structure length
82
Chain Sequence
KHSISDYTEAEFLQLVATICDADATSEEELDKLITHFGEMTEHPSGSDLIYYPEEGDDDSPSGIVNTVKQWRAANGKSGFKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Following evolutionary paths to high affinity and selectivity protein-protein interactions
rcsb
molecule keywords Colicin-E9 immunity protein
molecule tags Hydrolase
source organism Escherichia coli
total genus 24
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2009-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 3gklC00
4UHPB 2JBGA 2JAZA 1E0HA 2K5XA 2VLQA 1UNKA 1FR2A 1ZNVA 2VLPA 2GZIA 2K0DX 2WPTA 2ERHA 2GYKA 4F37A 1EMVA 2JB0A 2VLNA 4QKOA 1GXHA 3GKLC 3GJNA 2GZJA 2VLOA 1AYIA 1IMQA 1MZ8A 1BXIA 1CEIA 2NO8A 1IMPA 3U43A 2GZFA 2GZGA 2GZEA 1UJZA 7CEIA 5EW5E 1GXGA
chains in the Genus database with same CATH superfamily
2EHSA 1E0HA 2KOPA 2PEKA 2BHVA 2MR7A 3NTEA 2N98A 3CE7A 1Q7YQ 3E2DA 4XFZA 1ZNVA 2AVAA 3DS5A 2JYGA 3CCSP 1VKUA 2VLNA 2JU2A 2L6EA 4XRQA 3H47A 7CEIA 2L9FA 4H2XC 2GDWA 5EJDA 1VQMP 1YJNP 2EFJA 2LKIA 4GR6A 2GDXA 5I4TG 2KG6A 2KGAA 3Q20A 3DS4A 4U0AA 4H2YC 4XROA 2N5HA 2GZJA 2XXMA 2Z46A 2FQ2A 5HGLA 3CC2P 1HY8A 2AFEA 3DS0A 3RG6C 2XZ1C 2LOLA 1GPJA 1QVGO 4UHPB 4IPYA 1M6EX 2KG9A 1KQSO 3CCVP 3G0VA 2MVUA 2X2BA 3LMOA 2FACA 3CCUP 1EMVA 2K0XA 3GJNA 2P9XA 3B5IA 1NJIQ 3CPWO 2KOSA 3HZQA 5KP6B 1A43A 4U0BA 3G4SP 1M6NA 2LMLA 2JU1A 2K94A 2XZ0D 1VQ4P 1JJ2O 1Z6MA 2MVVA 1VQ6P 2AF8A 2LPKA 1RNIA 4MRTC 3G71P 1M1KQ 2FQ0A 3HYBA 4XFXA 2LIWA 2MF4A 3OW2O 1DV5A 3G21A 2JYLA 5F2OA 3CCJP 4CA3A 1RO0A 1EIAA 2QEXP 1EOQA 1AYIA 2OTLP 2M8PA 3EJDA 3GZMA 2QA4P 1ZMBA 5HGNA 4M0IA 1A8OA 3G1IA 3CMAP 1Q86Q 1DNYA 2K0YA 2M8LA 3CC4P 2KOOA 2EIAA 2GDYA 2VLOA 1BAJA 3DS1A 2KGEA 2JBGA 2JAZA 3G26A 2N5IA 2LF4A 3CMEP 1E6JP 1QVFO 1AF8A 2VLPA 2EG5A 1GXHA 3G1GA 2XV6A 1CEIA 4U0FA 1VQNP 2Z44A 1GXGA 5HGMA 5JPAA 2K93A 2FVEA 3WBHA 4U0EA 4COCA 2LL8A 2K0DX 2ONTA 2VSQA 1MZ8A 2KOQA 3CXCO 4PH0A 1RO2A 2N50A 3CCEP 4BPHA 1ACPA 4HKGA 1FR2A 2WPTA 1VQKP 1K9MQ 3VRLC 3GKLC 5BS1A 2K92A 2KG8A 2KGDA 2GZGA 1KLPA 3G28A 2GZEA 1VQOP 3CCLP 2KGCA 2JGPA 4BPFA 2CGQA 1OR5A 1VQ9P 1YHQP 3NY7B 1IMQA 3M1MA 1K73Q 4QNBA 2L0QA 3G6EP 1IMPA 4DG9A 2CQ8A 2JQ4A 1HQBA 5EW5E 1VQ7P 5KP8B 2Z45A 2VLQA 2MR8A 1YJWP 5HVCA 1KD1Q 4IZ6A 2ERHA 3LRYA 4F37A 3CCQP 3B4QA 3G29A 2PEOA 5F2KA 2PEJA 4XFYA 2OTJP 1VQ5P 3EJEA 4U0CA 4PXHB 2KORA 2KR5A 2N6YA 2CNRA 2GZIA 4PH1A 3H0DA 4QKOA 2MY5A 3P05A 2FAEA 2L22A 4NEOA 4WYMA 5DCKA 2DNWA 2LIUA 5HGOA 2L4BA 1KC8Q 1AUMA 1Q81Q 3GZLA 1UJZA 3CCMP 1VQ8P 3CD6P 1YI2P 2K5XA 1X3OA 4U0DA 3MGEA 2GYKA 2AFDA 3CC7P 5F2NA 2BUOA 3I56P 1W2BO 1S72P 2PEMA 4BPGA 1YJ9P 3DS3A 2QNWA 1N8RQ 4COPA 3DTJA 1YIJP 2EHTA 1VQPP 1D1DA 2PY8A 1T8KA 2JB0A 2FQ1A 2PNGA 1VQLP 2KODA 1BXIA 1YITP 2NO8A 3U43A 2GZFA 2LTEA 2KW2A 2KWLA 1QRJA 2ROQA 5BS2A 1UNKA 2CG5B 1Q82Q 1M74A 2MD9A 2N6ZA 5KP7B 3RG2A 3CCRP 1F80D 2JO0A 2PEIA 2M5RA 1L0IA 2FVAA 3DS2A 4PWVB 2PEQA 1IUQA 3I55P 3EJBA 3H4EA 5HV8A 1NQ4A 4H2WC 1K8AQ 1K30A 2XT1A 2FADA 2FHSC 3DPHA 2PENA 4R0MA 2OARA 1L0HA 2FVFA 1M90Q 2K2QA 2CWOA 2DGYA 5CZDB 4GR2A 2M8NA 2E1MA 1VHNA
chains in the Genus database with same CATH topology
4UHPB 2JBGA 2JAZA 1E0HA 2K5XA 2VLQA 1UNKA 1FR2A 1ZNVA 2VLPA 2GZIA 2K0DX 2WPTA 2ERHA 2GYKA 4F37A 1EMVA 2JB0A 2VLNA 4QKOA 1GXHA 3GKLC 3GJNA 2GZJA 2VLOA 1AYIA 1IMQA 1MZ8A 1BXIA 1CEIA 2NO8A 1IMPA 3U43A 2GZFA 2GZGA 2GZEA 1UJZA 7CEIA 5EW5E 1GXGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UHP B;  2JBG A;  2JAZ A;  1E0H A;  2K5X A;  2VLQ A;  1UNK A;  1FR2 A;  1ZNV A;  2VLP A;  2GZI A;  2K0D X;  2WPT A;  2ERH A;  2GYK A;  4F37 A;  1EMV A;  2JB0 A;  2VLN A;  4QKO A;  1GXH A;  3GKL C;  3GJN A;  2GZJ A;  2VLO A;  1AYI A;  1IMQ A;  1MZ8 A;  1BXI A;  1CEI A;  2NO8 A;  1IMP A;  3U43 A;  2GZF A;  2GZG A;  2GZE A;  1UJZ A;  7CEI A;  5EW5 E;  1GXG A; 
#chains in the Genus database with same CATH topology
 2EHS A;  1E0H A;  2KOP A;  2PEK A;  2BHV A;  2MR7 A;  3NTE A;  2N98 A;  3CE7 A;  1Q7Y Q;  3E2D A;  4XFZ A;  1ZNV A;  2AVA A;  3DS5 A;  2JYG A;  3CCS P;  1VKU A;  2VLN A;  2JU2 A;  2L6E A;  4XRQ A;  3H47 A;  7CEI A;  2L9F A;  4H2X C;  2GDW A;  5EJD A;  1VQM P;  1YJN P;  2EFJ A;  2LKI A;  4GR6 A;  2GDX A;  5I4T G;  2KG6 A;  2KGA A;  3Q20 A;  3DS4 A;  4U0A A;  4H2Y C;  4XRO A;  2N5H A;  2GZJ A;  2XXM A;  2Z46 A;  2FQ2 A;  5HGL A;  3CC2 P;  1HY8 A;  2AFE A;  3DS0 A;  3RG6 C;  2XZ1 C;  2LOL A;  1GPJ A;  1QVG O;  4UHP B;  4IPY A;  1M6E X;  2KG9 A;  1KQS O;  3CCV P;  3G0V A;  2MVU A;  2X2B A;  3LMO A;  2FAC A;  3CCU P;  1EMV A;  2K0X A;  3GJN A;  2P9X A;  3B5I A;  1NJI Q;  3CPW O;  2KOS A;  3HZQ A;  5KP6 B;  1A43 A;  4U0B A;  3G4S P;  1M6N A;  2LML A;  2JU1 A;  2K94 A;  2XZ0 D;  1VQ4 P;  1JJ2 O;  1Z6M A;  2MVV A;  1VQ6 P;  2AF8 A;  2LPK A;  1RNI A;  4MRT C;  3G71 P;  1M1K Q;  2FQ0 A;  3HYB A;  4XFX A;  2LIW A;  2MF4 A;  3OW2 O;  1DV5 A;  3G21 A;  2JYL A;  5F2O A;  3CCJ P;  4CA3 A;  1RO0 A;  1EIA A;  2QEX P;  1EOQ A;  1AYI A;  2OTL P;  2M8P A;  3EJD A;  3GZM A;  2QA4 P;  1ZMB A;  5HGN A;  4M0I A;  1A8O A;  3G1I A;  3CMA P;  1Q86 Q;  1DNY A;  2K0Y A;  2M8L A;  3CC4 P;  2KOO A;  2EIA A;  2GDY A;  2VLO A;  1BAJ A;  3DS1 A;  2KGE A;  2JBG A;  2JAZ A;  3G26 A;  2N5I A;  2LF4 A;  3CME P;  1E6J P;  1QVF O;  1AF8 A;  2VLP A;  2EG5 A;  1GXH A;  3G1G A;  2XV6 A;  1CEI A;  4U0F A;  1VQN P;  2Z44 A;  1GXG A;  5HGM A;  5JPA A;  2K93 A;  2FVE A;  3WBH A;  4U0E A;  4COC A;  2LL8 A;  2K0D X;  2ONT A;  2VSQ A;  1MZ8 A;  2KOQ A;  3CXC O;  4PH0 A;  1RO2 A;  2N50 A;  3CCE P;  4BPH A;  1ACP A;  4HKG A;  1FR2 A;  2WPT A;  1VQK P;  1K9M Q;  3VRL C;  3GKL C;  5BS1 A;  2K92 A;  2KG8 A;  2KGD A;  2GZG A;  1KLP A;  3G28 A;  2GZE A;  1VQO P;  3CCL P;  2KGC A;  2JGP A;  4BPF A;  2CGQ A;  1OR5 A;  1VQ9 P;  1YHQ P;  3NY7 B;  1IMQ A;  3M1M A;  1K73 Q;  4QNB A;  2L0Q A;  3G6E P;  1IMP A;  4DG9 A;  2CQ8 A;  2JQ4 A;  1HQB A;  5EW5 E;  1VQ7 P;  5KP8 B;  2Z45 A;  2VLQ A;  2MR8 A;  1YJW P;  5HVC A;  1KD1 Q;  4IZ6 A;  2ERH A;  3LRY A;  4F37 A;  3CCQ P;  3B4Q A;  3G29 A;  2PEO A;  5F2K A;  2PEJ A;  4XFY A;  2OTJ P;  1VQ5 P;  3EJE A;  4U0C A;  4PXH B;  2KOR A;  2KR5 A;  2N6Y A;  2CNR A;  2GZI A;  4PH1 A;  3H0D A;  4QKO A;  2MY5 A;  3P05 A;  2FAE A;  2L22 A;  4NEO A;  4WYM A;  5DCK A;  2DNW A;  2LIU A;  5HGO A;  2L4B A;  1KC8 Q;  1AUM A;  1Q81 Q;  3GZL A;  1UJZ A;  3CCM P;  1VQ8 P;  3CD6 P;  1YI2 P;  2K5X A;  1X3O A;  4U0D A;  3MGE A;  2GYK A;  2AFD A;  3CC7 P;  5F2N A;  2BUO A;  3I56 P;  1W2B O;  1S72 P;  2PEM A;  4BPG A;  1YJ9 P;  3DS3 A;  2QNW A;  1N8R Q;  4COP A;  3DTJ A;  1YIJ P;  2EHT A;  1VQP P;  1D1D A;  2PY8 A;  1T8K A;  2JB0 A;  2FQ1 A;  2PNG A;  1VQL P;  2KOD A;  1BXI A;  1YIT P;  2NO8 A;  3U43 A;  2GZF A;  2LTE A;  2KW2 A;  2KWL A;  1QRJ A;  2ROQ A;  5BS2 A;  1UNK A;  2CG5 B;  1Q82 Q;  1M74 A;  2MD9 A;  2N6Z A;  5KP7 B;  3RG2 A;  3CCR P;  1F80 D;  2JO0 A;  2PEI A;  2M5R A;  1L0I A;  2FVA A;  3DS2 A;  4PWV B;  2PEQ A;  1IUQ A;  3I55 P;  3EJB A;  3H4E A;  5HV8 A;  1NQ4 A;  4H2W C;  1K8A Q;  1K30 A;  2XT1 A;  2FAD A;  2FHS C;  3DPH A;  2PEN A;  4R0M A;  2OAR A;  1L0H A;  2FVF A;  1M90 Q;  2K2Q A;  2CWO A;  2DGY A;  5CZD B;  4GR2 A;  2M8N A;  2E1M A;  1VHN A; 
#chains in the Genus database with same CATH homology
 4UHP B;  2JBG A;  2JAZ A;  1E0H A;  2K5X A;  2VLQ A;  1UNK A;  1FR2 A;  1ZNV A;  2VLP A;  2GZI A;  2K0D X;  2WPT A;  2ERH A;  2GYK A;  4F37 A;  1EMV A;  2JB0 A;  2VLN A;  4QKO A;  1GXH A;  3GKL C;  3GJN A;  2GZJ A;  2VLO A;  1AYI A;  1IMQ A;  1MZ8 A;  1BXI A;  1CEI A;  2NO8 A;  1IMP A;  3U43 A;  2GZF A;  2GZG A;  2GZE A;  1UJZ A;  7CEI A;  5EW5 E;  1GXG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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