3GOVA

Crystal structure of the catalytic region of human masp-1
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
147
structure length
147
Chain Sequence
GNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords MASP-1
total genus 27
structure length 147
sequence length 147
ec nomenclature ec 3.4.21.-:
pdb deposition date 2009-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3govA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3govA02
2O39C 3CALA 2A55A 1NWVA 1PPQA 1ELVA 2EHFA 1HCCA 3MQLA 4MUCA 1H03P 1U5MA 4LOSA 2ERJA 3NFPI 4ONTD 1C1ZA 3RJ3D 1OK3A 3GOVA 5HYUB 2W80A 3EJHA 4ZH1D 5FO8C 1QO6A 2XRBA 4CSYA 1VVDA 3R62A 2B5ID 2CKUA 2KMSA 3ZD2A 1G4GA 4YNXA 4C16A 1HFHA 1HFIA 1QUBA 3O8EB 3ZD1A 2RKYA 1GKNA 1E5GA 3INBC 1CKLA 4IGDA 2YRAA 2EC3A 4AYIA 1E88A 2XRDA 3GXEA 3OXUD 2RLPA 1GPZA 1GHQB 5HZPB 4JHSA 3T5OA 1OK9A 1TPNA 2RL0A 2RKZA 1VVCA 2CG7A 5JPMG 2CG6A 5HYPA 1ZJKA 4PZ5A 2KRIA 4WJG2 5I0QB 1TPGA 1OJVA 4KKDA 1Q3XA 1OK2A 1H2QP 3L89M 4FXGG 1GKGA 3ZRZA 4DJZA 4B2RA 2XWBF 4K12A 2LOJA 2MCYA 4B2SA 2IZ4A 2MCZA 2JGWA 2V8EA 1MD7A 1LY2A 1OJYA 1FBRA 1E8BA 2G7IA 1SRZA 3KZJA 2W81A 1MD8A 4AYMA 1G4FA 4A5WB 2UWNA 1H04P 2RLQA 4AYDA 4F4OC 3M7PA 3OEDC 1O9AA 3OP8A 1QGBA 2XQWC 2QY0A 1UOTP 5HYTB 3IX0A 3ERBA 4LOTA 4J38B 2JRAA 1Z92B 2YBYA 3KXVA 3SW0X 1TPMA 3IU3I 3TVJA 1H2PP 1SS2A 2JGXA 4AYEA 2BZMA 1OK1A 2IZ3A 2WIIC 1OJWA 2XWJI
chains in the Genus database with same CATH superfamily
2O39C 3CALA 2A55A 1NWVA 1PPQA 1ELVA 2EHFA 1HCCA 3MQLA 4MUCA 1H03P 3VWOA 1U5MA 4LOSA 4MSLA 2ERJA 3NFPI 4ONTD 4APLA 1C1ZA 3RJ3D 3ZLDA 1OK3A 3GOVA 5HYUB 2W80A 3EJHA 4ZH1D 5FO8C 1QO6A 2XRBA 4CSYA 2ZYCA 4N7EA 1VVDA 3F6KA 2B5ID 2CKUA 3R62A 2KMSA 2X2ZA 3ZD2A 1G4GA 4YNXA 4C16A 1HFHA 1HFIA 1QUBA 1RLHA 3O8EB 3ZD1A 2RKYA 1GKNA 1E5GA 3INBC 1CKLA 4IGDA 2YRAA 2EC3A 4AYIA 1E88A 2XRDA 3GXEA 3OXUD 2RLPA 1GPZA 3K3TA 1GHQB 5HZPB 3CI0J 4JHSA 1OK9A 1TPNA 2RL0A 3T5OA 2RKZA 1VVCA 2CG7A 2Y8SA 5JPMG 2CG6A 5HYPA 1ZJKA 4PZ5A 2KRIA 4WJG2 5I0QB 1TPGA 1OJVA 4KKDA 1Q3XA 1OK2A 1H2QP 3L89M 4FXGG 2I2LA 1GKGA 3FGTA 3ZRZA 4DJZA 4B2RA 2XWBF 4K12A 2LOJA 2MCYA 4B2SA 2IZ4A 2MCZA 3WSYA 4PO7A 2JGWA 2V8EA 1MD7A 3NJAA 1LY2A 1OJYA 2Y8RA 1FBRA 1E8BA 2G7IA 1SRZA 3KZJA 2W81A 1MD8A 4AYMA 3FGRA 1G4FA 4A5WB 2UWNA 1H04P 2RLQA 4AYDA 4F4OC 3M7PA 3OEDC 1O9AA 3WSXA 3OP8A 1QGBA 2XQWC 4BWCA 2QY0A 1UOTP 5HYTB 3IX0A 2Y8TA 3ERBA 4LOTA 4J38B 5DN4A 3ZLEA 2JRAA 1Z92B 5DN5A 2YBYA 3KXVA 3SW0X 1TPMA 3IU3I 3TVJA 1H2PP 1SS2A 4YIZA 2JGXA 4AYEA 2BZMA 1OK1A 2IZ3A 2WIIC 1OJWA 2XWJI
chains in the Genus database with same CATH topology
2O39C 3CALA 2A55A 1NWVA 1PPQA 1ELVA 2EHFA 1HCCA 3MQLA 4MUCA 1H03P 1U5MA 4LOSA 2ERJA 3NFPI 4ONTD 1C1ZA 3RJ3D 1OK3A 3GOVA 5HYUB 2W80A 3EJHA 4ZH1D 5FO8C 1QO6A 2XRBA 4CSYA 1VVDA 3R62A 2B5ID 2CKUA 2KMSA 3ZD2A 1G4GA 4YNXA 4C16A 1HFHA 1HFIA 1QUBA 3O8EB 3ZD1A 2RKYA 1GKNA 1E5GA 3INBC 1CKLA 4IGDA 2YRAA 2EC3A 4AYIA 1E88A 2XRDA 3GXEA 3OXUD 2RLPA 1GPZA 1GHQB 5HZPB 4JHSA 3T5OA 1OK9A 1TPNA 2RL0A 2RKZA 1VVCA 2CG7A 5JPMG 2CG6A 5HYPA 1ZJKA 4PZ5A 2KRIA 4WJG2 5I0QB 1TPGA 1OJVA 4KKDA 1Q3XA 1OK2A 1H2QP 3L89M 4FXGG 1GKGA 3ZRZA 4DJZA 4B2RA 2XWBF 4K12A 2LOJA 2MCYA 4B2SA 2IZ4A 2MCZA 2JGWA 2V8EA 1MD7A 1LY2A 1OJYA 1FBRA 1E8BA 2G7IA 1SRZA 3KZJA 2W81A 1MD8A 4AYMA 1G4FA 4A5WB 2UWNA 1H04P 2RLQA 4AYDA 4F4OC 3M7PA 3OEDC 1O9AA 3OP8A 1QGBA 2XQWC 2QY0A 1UOTP 5HYTB 3IX0A 3ERBA 4LOTA 4J38B 2JRAA 1Z92B 2YBYA 3KXVA 3SW0X 1TPMA 3IU3I 3TVJA 1H2PP 1SS2A 2JGXA 4AYEA 2BZMA 1OK1A 2IZ3A 2WIIC 1OJWA 2XWJI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O39 C;  3CAL A;  2A55 A;  1NWV A;  1PPQ A;  1ELV A;  2EHF A;  1HCC A;  3MQL A;  4MUC A;  1H03 P;  1U5M A;  4LOS A;  2ERJ A;  3NFP I;  4ONT D;  1C1Z A;  3RJ3 D;  1OK3 A;  3GOV A;  5HYU B;  2W80 A;  3EJH A;  4ZH1 D;  5FO8 C;  1QO6 A;  2XRB A;  4CSY A;  1VVD A;  3R62 A;  2B5I D;  2CKU A;  2KMS A;  3ZD2 A;  1G4G A;  4YNX A;  4C16 A;  1HFH A;  1HFI A;  1QUB A;  3O8E B;  3ZD1 A;  2RKY A;  1GKN A;  1E5G A;  3INB C;  1CKL A;  4IGD A;  2YRA A;  2EC3 A;  4AYI A;  1E88 A;  2XRD A;  3GXE A;  3OXU D;  2RLP A;  1GPZ A;  1GHQ B;  5HZP B;  4JHS A;  3T5O A;  1OK9 A;  1TPN A;  2RL0 A;  2RKZ A;  1VVC A;  2CG7 A;  5JPM G;  2CG6 A;  5HYP A;  1ZJK A;  4PZ5 A;  2KRI A;  4WJG 2;  5I0Q B;  1TPG A;  1OJV A;  4KKD A;  1Q3X A;  1OK2 A;  1H2Q P;  3L89 M;  4FXG G;  1GKG A;  3ZRZ A;  4DJZ A;  4B2R A;  2XWB F;  4K12 A;  2LOJ A;  2MCY A;  4B2S A;  2IZ4 A;  2MCZ A;  2JGW A;  2V8E A;  1MD7 A;  1LY2 A;  1OJY A;  1FBR A;  1E8B A;  2G7I A;  1SRZ A;  3KZJ A;  2W81 A;  1MD8 A;  4AYM A;  1G4F A;  4A5W B;  2UWN A;  1H04 P;  2RLQ A;  4AYD A;  4F4O C;  3M7P A;  3OED C;  1O9A A;  3OP8 A;  1QGB A;  2XQW C;  2QY0 A;  1UOT P;  5HYT B;  3IX0 A;  3ERB A;  4LOT A;  4J38 B;  2JRA A;  1Z92 B;  2YBY A;  3KXV A;  3SW0 X;  1TPM A;  3IU3 I;  3TVJ A;  1H2P P;  1SS2 A;  2JGX A;  4AYE A;  2BZM A;  1OK1 A;  2IZ3 A;  2WII C;  1OJW A;  2XWJ I; 
#chains in the Genus database with same CATH topology
 2O39 C;  3CAL A;  2A55 A;  1NWV A;  1PPQ A;  1ELV A;  2EHF A;  1HCC A;  3MQL A;  4MUC A;  1H03 P;  3VWO A;  1U5M A;  4LOS A;  4MSL A;  2ERJ A;  3NFP I;  4ONT D;  4APL A;  1C1Z A;  3RJ3 D;  3ZLD A;  1OK3 A;  3GOV A;  5HYU B;  2W80 A;  3EJH A;  4ZH1 D;  5FO8 C;  1QO6 A;  2XRB A;  4CSY A;  2ZYC A;  4N7E A;  1VVD A;  3F6K A;  2B5I D;  2CKU A;  3R62 A;  2KMS A;  2X2Z A;  3ZD2 A;  1G4G A;  4YNX A;  4C16 A;  1HFH A;  1HFI A;  1QUB A;  1RLH A;  3O8E B;  3ZD1 A;  2RKY A;  1GKN A;  1E5G A;  3INB C;  1CKL A;  4IGD A;  2YRA A;  2EC3 A;  4AYI A;  1E88 A;  2XRD A;  3GXE A;  3OXU D;  2RLP A;  1GPZ A;  3K3T A;  1GHQ B;  5HZP B;  3CI0 J;  4JHS A;  1OK9 A;  1TPN A;  2RL0 A;  3T5O A;  2RKZ A;  1VVC A;  2CG7 A;  2Y8S A;  5JPM G;  2CG6 A;  5HYP A;  1ZJK A;  4PZ5 A;  2KRI A;  4WJG 2;  5I0Q B;  1TPG A;  1OJV A;  4KKD A;  1Q3X A;  1OK2 A;  1H2Q P;  3L89 M;  4FXG G;  2I2L A;  1GKG A;  3FGT A;  3ZRZ A;  4DJZ A;  4B2R A;  2XWB F;  4K12 A;  2LOJ A;  2MCY A;  4B2S A;  2IZ4 A;  2MCZ A;  3WSY A;  4PO7 A;  2JGW A;  2V8E A;  1MD7 A;  3NJA A;  1LY2 A;  1OJY A;  2Y8R A;  1FBR A;  1E8B A;  2G7I A;  1SRZ A;  3KZJ A;  2W81 A;  1MD8 A;  4AYM A;  3FGR A;  1G4F A;  4A5W B;  2UWN A;  1H04 P;  2RLQ A;  4AYD A;  4F4O C;  3M7P A;  3OED C;  1O9A A;  3WSX A;  3OP8 A;  1QGB A;  2XQW C;  4BWC A;  2QY0 A;  1UOT P;  5HYT B;  3IX0 A;  2Y8T A;  3ERB A;  4LOT A;  4J38 B;  5DN4 A;  3ZLE A;  2JRA A;  1Z92 B;  5DN5 A;  2YBY A;  3KXV A;  3SW0 X;  1TPM A;  3IU3 I;  3TVJ A;  1H2P P;  1SS2 A;  4YIZ A;  2JGX A;  4AYE A;  2BZM A;  1OK1 A;  2IZ3 A;  2WII C;  1OJW A;  2XWJ I; 
#chains in the Genus database with same CATH homology
 2O39 C;  3CAL A;  2A55 A;  1NWV A;  1PPQ A;  1ELV A;  2EHF A;  1HCC A;  3MQL A;  4MUC A;  1H03 P;  1U5M A;  4LOS A;  2ERJ A;  3NFP I;  4ONT D;  1C1Z A;  3RJ3 D;  1OK3 A;  3GOV A;  5HYU B;  2W80 A;  3EJH A;  4ZH1 D;  5FO8 C;  1QO6 A;  2XRB A;  4CSY A;  1VVD A;  3R62 A;  2B5I D;  2CKU A;  2KMS A;  3ZD2 A;  1G4G A;  4YNX A;  4C16 A;  1HFH A;  1HFI A;  1QUB A;  3O8E B;  3ZD1 A;  2RKY A;  1GKN A;  1E5G A;  3INB C;  1CKL A;  4IGD A;  2YRA A;  2EC3 A;  4AYI A;  1E88 A;  2XRD A;  3GXE A;  3OXU D;  2RLP A;  1GPZ A;  1GHQ B;  5HZP B;  4JHS A;  3T5O A;  1OK9 A;  1TPN A;  2RL0 A;  2RKZ A;  1VVC A;  2CG7 A;  5JPM G;  2CG6 A;  5HYP A;  1ZJK A;  4PZ5 A;  2KRI A;  4WJG 2;  5I0Q B;  1TPG A;  1OJV A;  4KKD A;  1Q3X A;  1OK2 A;  1H2Q P;  3L89 M;  4FXG G;  1GKG A;  3ZRZ A;  4DJZ A;  4B2R A;  2XWB F;  4K12 A;  2LOJ A;  2MCY A;  4B2S A;  2IZ4 A;  2MCZ A;  2JGW A;  2V8E A;  1MD7 A;  1LY2 A;  1OJY A;  1FBR A;  1E8B A;  2G7I A;  1SRZ A;  3KZJ A;  2W81 A;  1MD8 A;  4AYM A;  1G4F A;  4A5W B;  2UWN A;  1H04 P;  2RLQ A;  4AYD A;  4F4O C;  3M7P A;  3OED C;  1O9A A;  3OP8 A;  1QGB A;  2XQW C;  2QY0 A;  1UOT P;  5HYT B;  3IX0 A;  3ERB A;  4LOT A;  4J38 B;  2JRA A;  1Z92 B;  2YBY A;  3KXV A;  3SW0 X;  1TPM A;  3IU3 I;  3TVJ A;  1H2P P;  1SS2 A;  2JGX A;  4AYE A;  2BZM A;  1OK1 A;  2IZ3 A;  2WII C;  1OJW A;  2XWJ I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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