3H0WB

Human adometdc with 5'-deoxy-5'-[(n-dimethyl)amino]-8-methyl-adenosine
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
64
structure length
61
Chain Sequence
AHFFEGTEKLLEVWFSRQQPQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 6
structure length 61
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2009-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3h0wB01
3H0WB 3EP3B 3EP5B 3DZ6B 3H0VB 3DZ2B 1I7MB 1I7BB 1I79B 1JENB 3EP4B 1I72B 3EP8B 3DZ3B 3EP7B 1MHMB 3EP9B 3EPAB 3DZ5B 1I7CB 3DZ7B 3EP6B 3DZ4B 3EPBB 5TVOB
chains in the Genus database with same CATH superfamily
4F3YA 1DC4A 2IXAA 1CRWG 2HKIA 3QVSA 1GR0A 2PKRA 4WNIA 1DBVO 3L0DA 2X5JO 5A03A 1GYPA 3DZ7B 5EERA 1H6CA 1RM4A 3BTUA 1VC2A 2O4UX 1MC4A 1LA2A 3RVDA 3H0WB 5C7OO 3NT2A 1CERA 5CEFA 3H0VB 4DPLA 4LGVA 3HNPA 4HKTA 3WBBA 2OZPA 1LC0A 3KSDO 5AVOA 1GPDG 3PWSA 2PH5A 4ZICA 3E1KA 4R54A 4ZHSA 2H63A 4XQ9A 3LC2O 1H2HA 1U1IA 4MIYA 4PLPA 1U8FO 1H93A 3DR3A 1ZH8A 2HO5A 3E5RA 3C1AA 5J9GA 1OBFO 1P1JA 3EP8B 2G17A 3RC7A 3NT4A 4P8RA 1LC3A 3DZ4B 3DAPA 5A06A 3NTOA 4MVJE 1YWGO 1TVEA 3KV3O 2GYYA 2QZ9A 4XQCA 3EP5B 3EVNA 3OA2A 1RYEA 1DRVA 4MVJP 2CVOA 1J0XO 3ZJXA 4MVJH 1RM0A 3UUWA 4R4JA 1DC5A 4R41A 4NHEA 2HJSA 5JYFA 3PYXA 5JW6A 3PWKA 3V5NA 1VKNA 1T4BA 4JN6B 4DBVO 1JN0A 1P1HA 3RC2A 1PR3A 3WYBA 1VSUA 5A04A 5JYEA 3KSZO 3EP7B 5EIOA 2X5KO 4GPD1 1QKIA 4XR4A 3Q2IA 3EP6B 3ZDFA 4L9RA 1YL5A 5AQ1A 3Q2KA 1H9BA 1YS4A 1GYQA 5JYAA 1E7MA 1B7GO 2AXQA 5GZ1A 1GADO 3NT5A 3PZBA 3HXLA 4MVJM 2PKQO 2NQTA 1NQ5A 1YL6A 3RBVA 1I72B 1VSVA 3TUXA 4O89A 1EVJA 1TLTA 3BIOA 3L6OO 1ML3A 4XB1A 1EBFA 3B20A 1PQUA 4MVJI 3QVTA 3ZCXA 1DSSG 4BOYA 4XQEA 4EW6A 4XQGA 3DZ2B 1OZAA 3PFWO 1NBOA 3CPSA 3CEAA 3WGQA 1RM3A 1NPTO 2VYND 4R51A 4PG6A 3Q11A 3DZ5B 1I7CB 2BHLA 2DUUA 2NVWA 3IJPA 1H9AA 2D2IA 4MVJF 4O59O 3V2UA 3Q0EA 1H6BA 1PU2A 3EP3B 1DC3A 1BRMA 3K2BA 2Q4EA 3VAZA 3WBFA 5DDIP 3EP4B 1GL3A 3L4SO 1Q2XA 3DBVO 4K9DA 4TVBA 1RM5A 2I3GA 1H6AA 1TA4A 4MIOA 1XEAA 1NQOA 1J5PA 3PQVA 3K73O 1DIHA 1H6DA 4MVJG 2GZ1A 2GLXA 3LC1O 1DPGA 4Z0HO 2VYVD 1SZJG 3DZ6B 3DMTC 3WYCA 1PS8A 1JENB 2CZCA 3HJAA 5BNTA 3MZ0A 1I32A 3KUXA 1XYGA 4R3WA 3GPDG 1IHYA 1NWCA 2DPGA 3MOIA 3EZYA 3U3XA 5A02A 1CF2O 4R5HA 3K9QO 3ABIA 4YWJA 1YL7A 3B1KA 3TUTA 3QY9A 1NQAO 1C3VA 2BH9A 2VYNA 5EINA 3WB9A 3DB2A 3JSAA 3OHSX 2EP7A 3RC9A 5C7LO 5GZ6A 3RCBA 3WGOA 1FF9A 2R00C 1QXSA 2X0NA 2GZ2A 3CMCO 3M2TA 1OFGA 4HADA 4PG4A 4MJLA 2YYYA 3BTVA 4RL6A 1GCUA 1VKOA 2O48X 1I7MB 1E5LA 3VOSA 3QV1A 4FB5A 3EP9B 1P1IA 3DOCA 2XF8A 3CINA 1QMHA 2PKQP 4GMGA 3IDSA 3IWBB 3OA0A 3H9EO 4XB2A 1PQPA 4GMFA 1DRWA 3QW2A 2VYVA 3RC1A 4INAA 2IXBA 3STHA 1DAPA 3GDOA 2G82A 3FD8A 4LSMA 1E77A 2GD1O 3GNQA 3UW3A 3HQ4O 1IHXA 4MIEA 4MKXA 3TW3A 4H3VA 4LRTB 3PYMA 4CLQA 1JKIA 2DC1A 3DMTA 3TV1A 2GZ3A 3QVWA 2I3AA 1VM6A 3GFGA 4XRGA 3IWDB 4DPKA 4O63O 2B4RO 3LVFO 3IWCB 1I79B 1RYDA 3INGA 1E7YA 2EJWA 2POQX 3PZRA 5GZ3A 3EPAB 4PG5A 2FPNA 3F4LA 3QVXA 4MKZA 1UYJA 5C7IO 4O8JA 1S7CA 1MB4A 4R5MA 3O9ZA 1NVMB 3NTQA 3Q1LA 4QX6A 3E6AA 4MVJD 4LRSB 5TVOB 4II7A 3BTSA 1EBUA 3PYLA 4MINA 3I23A 1I33A 4IQ8A 1DC6A 4PG7A 3DO5A 1P9LA 5T73A 3LC7O 1YDWA 3KGDA 5M6DA 3IP3A 4R3NA 4GQAA 2I5PO 3EC7A 2R00A 1QMIA 4YDRA 2B4TO 3B1JA 1HDGO 1K3TA 1TB4A 2YV3A 3EPBB 1GD1O 2P2SA 4L8VA 1ARZA 3C8MA 1NX6A 3V1YA 1GAEO 1P1FA 1F06A 3HSKA 1H94A 4DPMA 2EP5A 1MHMB 4N54A 3NTRA 3WGZA 4AK1A 3DTYA 1T4DA 4DIBA 1P1KA 1A7KA 4PG8A 5KVSA 3OQBA 3FHLA 1JKFA 5KVQA 2Q49A 3E18A 1ZNQO 3E82A 1I7BB 2DBVO 3CIFA 3E9MA 3DZ3B 3EUWA 2Q22A 1Q7GA 1E5QA 2DAPA 4WOJA 4IQ0A 5A05A 3TZ6A 1DRUA 3MTJA 5JY6A 5EESA 3WGYA 4MVJA 4WNCA 4KOAA 1NWHA
chains in the Genus database with same CATH topology
3H0WB 1TLUA 3DZ7A 3EP3B 3EP6A 1I7CA 2IIIA 3DZ4A 3EP5B 1MSVA 1VR7A 3DZ6B 3DZ2B 3H0VB 3EPBA 5TVOA 1I7MB 1I7BB 1I79B 3H0WA 1JENB 3EP4B 1I72B 3EP3A 3EP8B 1JL0A 3DZ3B 3EP7B 1MHMB 3EP9B 3EPAB 3EP5A 3DZ5B 3DZ2A 3DZ6A 3H0VA 5TVOB 1I7CB 3DZ7B 1I7MA 1I7BA 3EP6B 1JENA 3DZ4B 1I79A 3EP8A 3EP4A 1I72A 1TMIA 3EP7A 1MHMA 3DZ3A 3EP9A 3EPBB 3EPAA 3DZ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H0W B;  3EP3 B;  3EP5 B;  3DZ6 B;  3H0V B;  3DZ2 B;  1I7M B;  1I7B B;  1I79 B;  1JEN B;  3EP4 B;  1I72 B;  3EP8 B;  3DZ3 B;  3EP7 B;  1MHM B;  3EP9 B;  3EPA B;  3DZ5 B;  1I7C B;  3DZ7 B;  3EP6 B;  3DZ4 B;  3EPB B;  5TVO B; 
#chains in the Genus database with same CATH topology
 4F3Y A;  1DC4 A;  2IXA A;  1CRW G;  2HKI A;  3QVS A;  1GR0 A;  2PKR A;  4WNI A;  1DBV O;  3L0D A;  2X5J O;  5A03 A;  1GYP A;  3DZ7 B;  5EER A;  1H6C A;  1RM4 A;  3BTU A;  1VC2 A;  2O4U X;  1MC4 A;  1LA2 A;  3RVD A;  3H0W B;  5C7O O;  3NT2 A;  1CER A;  5CEF A;  3H0V B;  4DPL A;  4LGV A;  3HNP A;  4HKT A;  3WBB A;  2OZP A;  1LC0 A;  3KSD O;  5AVO A;  1GPD G;  3PWS A;  2PH5 A;  4ZIC A;  3E1K A;  4R54 A;  4ZHS A;  2H63 A;  4XQ9 A;  3LC2 O;  1H2H A;  1U1I A;  4MIY A;  4PLP A;  1U8F O;  1H93 A;  3DR3 A;  1ZH8 A;  2HO5 A;  3E5R A;  3C1A A;  5J9G A;  1OBF O;  1P1J A;  3EP8 B;  2G17 A;  3RC7 A;  3NT4 A;  4P8R A;  1LC3 A;  3DZ4 B;  3DAP A;  5A06 A;  3NTO A;  4MVJ E;  1YWG O;  1TVE A;  3KV3 O;  2GYY A;  2QZ9 A;  4XQC A;  3EP5 B;  3EVN A;  3OA2 A;  1RYE A;  1DRV A;  4MVJ P;  2CVO A;  1J0X O;  3ZJX A;  4MVJ H;  1RM0 A;  3UUW A;  4R4J A;  1DC5 A;  4R41 A;  4NHE A;  2HJS A;  5JYF A;  3PYX A;  5JW6 A;  3PWK A;  3V5N A;  1VKN A;  1T4B A;  4JN6 B;  4DBV O;  1JN0 A;  1P1H A;  3RC2 A;  1PR3 A;  3WYB A;  1VSU A;  5A04 A;  5JYE A;  3KSZ O;  3EP7 B;  5EIO A;  2X5K O;  4GPD 1;  1QKI A;  4XR4 A;  3Q2I A;  3EP6 B;  3ZDF A;  4L9R A;  1YL5 A;  5AQ1 A;  3Q2K A;  1H9B A;  1YS4 A;  1GYQ A;  5JYA A;  1E7M A;  1B7G O;  2AXQ A;  5GZ1 A;  1GAD O;  3NT5 A;  3PZB A;  3HXL A;  4MVJ M;  2PKQ O;  2NQT A;  1NQ5 A;  1YL6 A;  3RBV A;  1I72 B;  1VSV A;  3TUX A;  4O89 A;  1EVJ A;  1TLT A;  3BIO A;  3L6O O;  1ML3 A;  4XB1 A;  1EBF A;  3B20 A;  1PQU A;  4MVJ I;  3QVT A;  3ZCX A;  1DSS G;  4BOY A;  4XQE A;  4EW6 A;  4XQG A;  3DZ2 B;  1OZA A;  3PFW O;  1NBO A;  3CPS A;  3CEA A;  3WGQ A;  1RM3 A;  1NPT O;  2VYN D;  4R51 A;  4PG6 A;  3Q11 A;  3DZ5 B;  1I7C B;  2BHL A;  2DUU A;  2NVW A;  3IJP A;  1H9A A;  2D2I A;  4MVJ F;  4O59 O;  3V2U A;  3Q0E A;  1H6B A;  1PU2 A;  3EP3 B;  1DC3 A;  1BRM A;  3K2B A;  2Q4E A;  3VAZ A;  3WBF A;  5DDI P;  3EP4 B;  1GL3 A;  3L4S O;  1Q2X A;  3DBV O;  4K9D A;  4TVB A;  1RM5 A;  2I3G A;  1H6A A;  1TA4 A;  4MIO A;  1XEA A;  1NQO A;  1J5P A;  3PQV A;  3K73 O;  1DIH A;  1H6D A;  4MVJ G;  2GZ1 A;  2GLX A;  3LC1 O;  1DPG A;  4Z0H O;  2VYV D;  1SZJ G;  3DZ6 B;  3DMT C;  3WYC A;  1PS8 A;  1JEN B;  2CZC A;  3HJA A;  5BNT A;  3MZ0 A;  1I32 A;  3KUX A;  1XYG A;  4R3W A;  3GPD G;  1IHY A;  1NWC A;  2DPG A;  3MOI A;  3EZY A;  3U3X A;  5A02 A;  1CF2 O;  4R5H A;  3K9Q O;  3ABI A;  4YWJ A;  1YL7 A;  3B1K A;  3TUT A;  3QY9 A;  1NQA O;  1C3V A;  2BH9 A;  2VYN A;  5EIN A;  3WB9 A;  3DB2 A;  3JSA A;  3OHS X;  2EP7 A;  3RC9 A;  5C7L O;  5GZ6 A;  3RCB A;  3WGO A;  1FF9 A;  2R00 C;  1QXS A;  2X0N A;  2GZ2 A;  3CMC O;  3M2T A;  1OFG A;  4HAD A;  4PG4 A;  4MJL A;  2YYY A;  3BTV A;  4RL6 A;  1GCU A;  1VKO A;  2O48 X;  1I7M B;  1E5L A;  3VOS A;  3QV1 A;  4FB5 A;  3EP9 B;  1P1I A;  3DOC A;  2XF8 A;  3CIN A;  1QMH A;  2PKQ P;  4GMG A;  3IDS A;  3IWB B;  3OA0 A;  3H9E O;  4XB2 A;  1PQP A;  4GMF A;  1DRW A;  3QW2 A;  2VYV A;  3RC1 A;  4INA A;  2IXB A;  3STH A;  1DAP A;  3GDO A;  2G82 A;  3FD8 A;  4LSM A;  1E77 A;  2GD1 O;  3GNQ A;  3UW3 A;  3HQ4 O;  1IHX A;  4MIE A;  4MKX A;  3TW3 A;  4H3V A;  4LRT B;  3PYM A;  4CLQ A;  1JKI A;  2DC1 A;  3DMT A;  3TV1 A;  2GZ3 A;  3QVW A;  2I3A A;  1VM6 A;  3GFG A;  4XRG A;  3IWD B;  4DPK A;  4O63 O;  2B4R O;  3LVF O;  3IWC B;  1I79 B;  1RYD A;  3ING A;  1E7Y A;  2EJW A;  2POQ X;  3PZR A;  5GZ3 A;  3EPA B;  4PG5 A;  2FPN A;  3F4L A;  3QVX A;  4MKZ A;  1UYJ A;  5C7I O;  4O8J A;  1S7C A;  1MB4 A;  4R5M A;  3O9Z A;  1NVM B;  3NTQ A;  3Q1L A;  4QX6 A;  3E6A A;  4MVJ D;  4LRS B;  5TVO B;  4II7 A;  3BTS A;  1EBU A;  3PYL A;  4MIN A;  3I23 A;  1I33 A;  4IQ8 A;  1DC6 A;  4PG7 A;  3DO5 A;  1P9L A;  5T73 A;  3LC7 O;  1YDW A;  3KGD A;  5M6D A;  3IP3 A;  4R3N A;  4GQA A;  2I5P O;  3EC7 A;  2R00 A;  1QMI A;  4YDR A;  2B4T O;  3B1J A;  1HDG O;  1K3T A;  1TB4 A;  2YV3 A;  3EPB B;  1GD1 O;  2P2S A;  4L8V A;  1ARZ A;  3C8M A;  1NX6 A;  3V1Y A;  1GAE O;  1P1F A;  1F06 A;  3HSK A;  1H94 A;  4DPM A;  2EP5 A;  1MHM B;  4N54 A;  3NTR A;  3WGZ A;  4AK1 A;  3DTY A;  1T4D A;  4DIB A;  1P1K A;  1A7K A;  4PG8 A;  5KVS A;  3OQB A;  3FHL A;  1JKF A;  5KVQ A;  2Q49 A;  3E18 A;  1ZNQ O;  3E82 A;  1I7B B;  2DBV O;  3CIF A;  3E9M A;  3DZ3 B;  3EUW A;  2Q22 A;  1Q7G A;  1E5Q A;  2DAP A;  4WOJ A;  4IQ0 A;  5A05 A;  3TZ6 A;  1DRU A;  3MTJ A;  5JY6 A;  5EES A;  3WGY A;  4MVJ A;  4WNC A;  4KOA A;  1NWH A; 
#chains in the Genus database with same CATH homology
 3H0W B;  1TLU A;  3DZ7 A;  3EP3 B;  3EP6 A;  1I7C A;  2III A;  3DZ4 A;  3EP5 B;  1MSV A;  1VR7 A;  3DZ6 B;  3DZ2 B;  3H0V B;  3EPB A;  5TVO A;  1I7M B;  1I7B B;  1I79 B;  3H0W A;  1JEN B;  3EP4 B;  1I72 B;  3EP3 A;  3EP8 B;  1JL0 A;  3DZ3 B;  3EP7 B;  1MHM B;  3EP9 B;  3EPA B;  3EP5 A;  3DZ5 B;  3DZ2 A;  3DZ6 A;  3H0V A;  5TVO B;  1I7C B;  3DZ7 B;  1I7M A;  1I7B A;  3EP6 B;  1JEN A;  3DZ4 B;  1I79 A;  3EP8 A;  3EP4 A;  1I72 A;  1TMI A;  3EP7 A;  1MHM A;  3DZ3 A;  3EP9 A;  3EPB B;  3EPA A;  3DZ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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