3HWOA

Crystal structure of escherichia coli enterobactin-specific isochorismate synthase entc in complex with isochorismate
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
379
structure length
379
Chain Sequence
MATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Isochorismate synthase entC
publication title Crystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes
pubmed doi rcsb
source organism Escherichia coli
total genus 110
structure length 379
sequence length 379
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2009-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 3hwoA00
5JZDA 3RV7A 3HWOA 3BZNA 3H9MA 1K0GA 2FN1A 2G5FA 1I7SA 3VEHA 3OS6A 5JY8A 3GSEA 2I6YA 2EUAA 5JY4A 3RV8A 3LOGA 3RV9A 5JY9A 3BZMA 5CWAA 3ST6A 4GRHA 1QDLA 5KCKA 3R75A 1I1QA 3R74A 2FN0A 5JY4B 1K0EA 3RV6A 3R76A 5JXZA 1I7QA
chains in the Genus database with same CATH superfamily
5JZDA 3RV7A 3HWOA 3BZNA 3H9MA 1K0GA 2FN1A 2G5FA 1I7SA 3VEHA 3OS6A 5JY8A 3GSEA 2I6YA 2EUAA 5JY4A 3RV8A 3LOGA 3RV9A 5JY9A 3BZMA 5CWAA 3ST6A 4GRHA 1QDLA 5KCKA 3R75A 1I1QA 3R74A 2FN0A 5JY4B 1K0EA 3RV6A 3R76A 5JXZA 1I7QA
chains in the Genus database with same CATH topology
5JZDA 3RV7A 3HWOA 3BZNA 3H9MA 1K0GA 2FN1A 2G5FA 1I7SA 3VEHA 3OS6A 5JY8A 3GSEA 2I6YA 2EUAA 5JY4A 3RV8A 3LOGA 3RV9A 5JY9A 3BZMA 5CWAA 3ST6A 4GRHA 1QDLA 5KCKA 3R75A 1I1QA 3R74A 2FN0A 5JY4B 1K0EA 3RV6A 3R76A 5JXZA 1I7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JZD A;  3RV7 A;  3HWO A;  3BZN A;  3H9M A;  1K0G A;  2FN1 A;  2G5F A;  1I7S A;  3VEH A;  3OS6 A;  5JY8 A;  3GSE A;  2I6Y A;  2EUA A;  5JY4 A;  3RV8 A;  3LOG A;  3RV9 A;  5JY9 A;  3BZM A;  5CWA A;  3ST6 A;  4GRH A;  1QDL A;  5KCK A;  3R75 A;  1I1Q A;  3R74 A;  2FN0 A;  5JY4 B;  1K0E A;  3RV6 A;  3R76 A;  5JXZ A;  1I7Q A; 
#chains in the Genus database with same CATH topology
 5JZD A;  3RV7 A;  3HWO A;  3BZN A;  3H9M A;  1K0G A;  2FN1 A;  2G5F A;  1I7S A;  3VEH A;  3OS6 A;  5JY8 A;  3GSE A;  2I6Y A;  2EUA A;  5JY4 A;  3RV8 A;  3LOG A;  3RV9 A;  5JY9 A;  3BZM A;  5CWA A;  3ST6 A;  4GRH A;  1QDL A;  5KCK A;  3R75 A;  1I1Q A;  3R74 A;  2FN0 A;  5JY4 B;  1K0E A;  3RV6 A;  3R76 A;  5JXZ A;  1I7Q A; 
#chains in the Genus database with same CATH homology
 5JZD A;  3RV7 A;  3HWO A;  3BZN A;  3H9M A;  1K0G A;  2FN1 A;  2G5F A;  1I7S A;  3VEH A;  3OS6 A;  5JY8 A;  3GSE A;  2I6Y A;  2EUA A;  5JY4 A;  3RV8 A;  3LOG A;  3RV9 A;  5JY9 A;  3BZM A;  5CWA A;  3ST6 A;  4GRH A;  1QDL A;  5KCK A;  3R75 A;  1I1Q A;  3R74 A;  2FN0 A;  5JY4 B;  1K0E A;  3RV6 A;  3R76 A;  5JXZ A;  1I7Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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