3HY7A

Crystal structure of the catalytic domain of adamts-5 in complex with marimastat
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
217
structure length
217
Chain Sequence
SRARQVELLLVADASMARKYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSHDDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors
pubmed doi rcsb
molecule keywords A disintegrin and metalloproteinase with thrombospondin moti
molecule tags Hydrolase
source organism Homo sapiens
total genus 73
structure length 217
sequence length 217
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01421 Reprolysin Reprolysin (M12B) family zinc metalloprotease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3hy7A00
2D1NA 2W12A 3P24A 4H1QA 2TCLA 2OY2A 3DL1A 1OMJA 4FVLA 5D1SA 5BPAA 1Z3JA 1ZP5A 3LEAA 1JJ9A 1SU3A 3I7IA 4FXQA 3CKIA 1XFVA 3AYKA 1CXVA 2W0DA 3SHIA 3LMCA 4ZR5A 3EWJA 1G49A 1XUCA 1YP1A 3LKAA 1SLMA 3O64A 1BKCE 1JAOA 2OW0A 1C3IA 2E3XA 1HTDA 2K2GA 3KWVC 5L7FA 1D5JA 1J7NA 1S4BP 3B92A 3K7NA 3F18A 4PKRA 2X3CA 1XURA 2POJA 1D7XA 3KEKA 3GBOA 5BOYA 1ND1A 3LE9A 1H71P 2W15A 3LILA 1D8MA 1Y8JA 1QICA 3WV1A 3EDZA 1SLNA 5D1TA 4H82A 5B5OA 2OW9A 4PKSA 2X7MA 4DD8A 4FXYP 2OXWA 3OHOA 3HBVP 2J83A 3EDIA 3HY9A 1MMQA 3LGPA 5B5PA 2ERPA 1BZSA 4H2EA 1AF0A 3EDGA 2OI0A 1GXDA 3F15A 2MZEA 1FBLA 1MMBA 3G42A 3HY7A 3N2UA 2K9CA 2X3BA 2WO9A 4H3XA 2E2DA 2YB9A 4A3WA 5H8XA 2OW2A 1KUGA 1ZTQA 3NX7A 3L0VA 4DV8A 4G9LA 4EFSA 4L63A 1AYKA 4ON1A 2FV5A 2AIGP 4H84A 4H49A 5CZMA 1Q3AA 3UVCA 1UTTA 3G5CA 3LQBA 1R1JA 2OXUA 3P1VA 966CA 4L19A 4G0DA 2L0RA 3O2XA 1JH1A 1HFSA 2I47A 5JMYA 1KUHA 1R1IA 2DW0A 3BA0A 1HV5A 4XM6A 4AIGA 1PWWA 2PJTA 1K7IA 1QIAA 3LIRA 1UTZA 1OM7A 4J4MA 1GKDA 3ZVSA 3ZUKA 4IUWA 1XFWA 3TSKA 1A86A 1QIBA 1XFYA 1KAPP 4JP4A 1BIWA 3TVCA 4DF9A 2N8RA 3HB2P 1G05A 1ASTA 1SRPA 2J0TA 3DNGA 3ELMA 4PKUA 1G12A 3TS4A 4FU4A 1XFUA 1R1HA 3F16A 1PWQA 5I4OA 2DDFA 3V96B 1G4KA 1OS2A 1OM8A 3LJGA 4AYKA 1UMSA 1GKCA 1KUIA 2OVXA 3L0TA 3KMEA 2Z2DA 3KMCA 4I03A 3RTSA 3LUMA 1C7KA 2OW1A 1IABA 3LUNA 3KEJA 1QJJA 2WO8A 5I2ZA 2D1OA 2RJPA 1D8FA 1RM8A 4GWNA 4WKIA 1A85A 4HX3A 1JAQA 2KRJA 3EDHA 1USNA 1WNIA 4IJOA 2EROA 1BUDA 3VI1A 5I3MA 3KRYA 5D2BA 1HFCA 3LK8A 1I1IP 1ATLA 4QKZA 3B8ZA 3EHYA 2MLRA 2HU6A 3DPFA 1XFXA 1SMPA 1CGFA 4XM8A 1KUKA 2OZRA 1GE6A 2V4BA 1ROSA 1JIZA 1GO7P 2X3AA 2O3EA 3DSLA 3HYGA 2Y6CA 3F1AA 1BUVM 4XCTA 1PWPA 2A8HA 1GO8P 3HDBA 4IN9A 2DW2A 1EAKA 3USNA 2DDYA 2AYKA 1JANA 2JNPA 3VTGA 1BSWA 5BOTA 2Y6DA 1UMTA 4H30A 4I35A 3U1RA 1OS9A 1ZVXA 2CKIA 3HBUP 1IADA 1PWVA 3N2VA 1R54A 1JK3A 1Y0VA 1SATA 3AIGA 1O0QA 3K7LA 1CIZA 1G9KA 4H76A 4JPAA 3MA2A 4ILWD 4XBHA 1EUBA 4JIJA 1MNCA 4WK7A 3LJZA 4GR0A 1QUAA 1FLSA 1GE5A 1YQYA 4WZVA 1GE7A 4WKEA 5D7WA 5LABA 2W14A 1AKLA 1L6JA 4GQLA 1DTHA 2XS3A 3F17A 1MMPA 2OY4A 1OM6A 2OXZA 5I0LA 1UEAA 2DW1A 1IAEA 1O0TA 5D1UA 2QPJA 4PKQA 1C8TA 1FM1A 2USNA 3KHIA 2MLSA 2JT5A 1BQQM 3HDAP 3EHXA 4GR8A 4HMAA 830CA 1I76A 2YIGA 3F19A 1IACA 4Q1LA 4L6TA 1R55A 1CAQA 2ERQA 3E8RA 3KECA 2WOAA 1HOVA 4XM7A 1ZS0A 1OO9A 1MMRA 1HY7A 2JIHA 1KUFA 4JA1A 3LIKA 1K7GA 3DPEA 1XFZA 3B2ZA 3LJTA 1KBCA 3AYUA 4AUOA 2MZHA 3Q2GA 3I7GA 3Q2HA 4GR3A 2FV9A 3TT4A 1BQOA 1Y93A 1JKYA 1K7QA 1CQRA 1BM6A 1BKCI 5L79A 1IAGA 2JT6A 1BKCA 4GF1A 2W13A 456CA 4JQGA 2JSDA 3WV3A 1QJIA 3LQ0A 4WF6A 3OHLA 2RJQA 5I12A 4A7BA 4GUYA 1JAPA 1YCMA 2SRTA 1CK7A 1ZXVA 1CGLA 1B3DA 4AXQA 5CUHA 4PKWA 1ZXCA 1RMZA 2XS4A 2O36A 3ZXHA 2MZIA 1EB6A 3RTTA 1IAAA 1B8YA 5D3CA 1YOUA 3DWBA 1CGEA 1PWUA 2OVZA 1XUDA 4GWMA 4PKVA 4R3VA 4DPEA 4PKTA 1I73A 5I43A 3WV2A 1JIWP 2CLTA 1DMTA 4CTHA 5CXAA
chains in the Genus database with same CATH superfamily
2D1NA 2W12A 3P24A 4H1QA 2TCLA 2OY2A 3DL1A 1OMJA 4FVLA 5D1SA 5BPAA 1Z3JA 1ZP5A 3DTIA 3LEAA 1JJ9A 1SU3A 3I7IA 4FXQA 3CKIA 1XFVA 3AYKA 1CXVA 2W0DA 3SHIA 3LMCA 4ZR5A 3EWJA 1G49A 1XUCA 1YP1A 3LKAA 1SLMA 3O64A 1BKCE 1JAOA 2OW0A 1C3IA 2E3XA 1HTDA 2K2GA 3KWVC 5L7FA 1D5JA 1J7NA 1S4BP 3B92A 3K7NA 3F18A 1XM5A 4PKRA 2X3CA 1XURA 2POJA 1D7XA 3KEKA 3GBOA 5BOYA 1ND1A 3LE9A 1H71P 2W15A 3LILA 1D8MA 1Y8JA 1QICA 3WV1A 3EDZA 1SLNA 5D1TA 4H82A 5B5OA 2OW9A 4PKSA 2X7MA 4DD8A 4FXYP 2OXWA 3OHOA 3HBVP 2J83A 3EDIA 3HY9A 1MMQA 3LGPA 3DTKA 2ERPA 5B5PA 1BZSA 4H2EA 1AF0A 1TVIA 2OI0A 1GXDA 3EDGA 3F15A 2MZEA 1FBLA 1MMBA 3G42A 3HY7A 3N2UA 2K9CA 2X3BA 2WO9A 4H3XA 2E2DA 2YB9A 4A3WA 5H8XA 2OW2A 1KUGA 1ZTQA 3NX7A 3L0VA 4DV8A 4G9LA 4EFSA 4L63A 1AYKA 4ON1A 2FV5A 2AIGP 4H84A 4H49A 5CZMA 1Q3AA 3UVCA 1UTTA 3G5CA 3LQBA 1R1JA 2OXUA 3P1VA 966CA 4L19A 4G0DA 2L0RA 3O2XA 1JH1A 1HFSA 2I47A 5JMYA 1KUHA 1R1IA 2DW0A 3BA0A 1HV5A 4XM6A 4AIGA 1PWWA 2PJTA 1K7IA 1QIAA 3LIRA 1UTZA 1OM7A 4J4MA 1GKDA 3ZVSA 3ZUKA 4IUWA 1XFWA 3TSKA 1A86A 1QIBA 1XFYA 1KAPP 4JP4A 1BIWA 3TVCA 4DF9A 2N8RA 3HB2P 1G05A 1ASTA 1SRPA 2J0TA 3DNGA 3ELMA 4PKUA 1G12A 3TS4A 4FU4A 1XFUA 1R1HA 3F16A 1PWQA 5I4OA 2DDFA 3V96B 1G4KA 1OS2A 1OM8A 3LJGA 4AYKA 1UMSA 1GKCA 1KUIA 2OVXA 3L0TA 3KMEA 2Z2DA 3KMCA 4I03A 3RTSA 3LUMA 1C7KA 2OW1A 1IABA 3LUNA 3KEJA 4L7AA 1QJJA 2WO8A 5I2ZA 2D1OA 2RJPA 1D8FA 1RM8A 4GWNA 4WKIA 1A85A 4HX3A 1JAQA 2KRJA 3EDHA 1USNA 1WNIA 4IJOA 2EROA 1BUDA 3VI1A 5I3MA 3KRYA 5D2BA 1HFCA 3LK8A 1I1IP 1ATLA 4QKZA 3B8ZA 3EHYA 2MLRA 2HU6A 3DPFA 1XFXA 1SMPA 1CGFA 4XM8A 1KUKA 2OZRA 1GE6A 2V4BA 1ROSA 1JIZA 1GO7P 2X3AA 2O3EA 3DSLA 3HYGA 2Y6CA 3F1AA 1BUVM 4XCTA 1PWPA 2A8HA 1GO8P 3HDBA 4IN9A 2DW2A 1EAKA 1XAXA 3USNA 2DDYA 2AYKA 1JANA 2JNPA 3VTGA 1BSWA 5BOTA 2Y6DA 1UMTA 4H30A 4I35A 3U1RA 1OS9A 1ZVXA 2CKIA 3HBUP 1IADA 1PWVA 3N2VA 1R54A 1JK3A 1Y0VA 1SATA 3AIGA 1O0QA 3K7LA 1CIZA 1G9KA 4H76A 4JPAA 3MA2A 4ILWD 4XBHA 1EUBA 4JIJA 1MNCA 4WK7A 3LJZA 4GR0A 1QUAA 1FLSA 1GE5A 1YQYA 4WZVA 1GE7A 4WKEA 5D7WA 5LABA 2W14A 1AKLA 1L6JA 4GQLA 1DTHA 2XS3A 3F17A 1MMPA 2OY4A 1OM6A 2OXZA 5I0LA 1UEAA 2DW1A 1IAEA 1O0TA 5D1UA 2QPJA 4PKQA 1C8TA 1FM1A 2USNA 3KHIA 2MLSA 2JT5A 1BQQM 3HDAP 3EHXA 4GR8A 4HMAA 830CA 1I76A 2YIGA 3F19A 1IACA 4Q1LA 4L6TA 1R55A 1CAQA 2ERQA 3E8RA 3KECA 2WOAA 1HOVA 2YUFA 1OZ9A 4XM7A 1ZS0A 1OO9A 1MMRA 1HY7A 2JIHA 1KUFA 4JA1A 3LIKA 1K7GA 3DPEA 1XFZA 3B2ZA 3LJTA 1KBCA 3AYUA 4AUOA 2MZHA 3Q2GA 3I7GA 3Q2HA 4GR3A 2FV9A 3TT4A 1BQOA 1Y93A 1JKYA 1K7QA 1CQRA 1BM6A 1BKCI 5L79A 1IAGA 2JT6A 1BKCA 4GF1A 2W13A 456CA 4JQGA 2JSDA 3WV3A 1QJIA 3LQ0A 4WF6A 3OHLA 2RJQA 5I12A 4A7BA 4GUYA 1JAPA 1YCMA 2SRTA 1CK7A 1ZXVA 1CGLA 1B3DA 4AXQA 5CUHA 4PKWA 1ZXCA 1RMZA 2XS4A 2O36A 3ZXHA 2MZIA 1EB6A 3RTTA 1IAAA 1B8YA 5D3CA 1YOUA 3DWBA 1CGEA 1PWUA 2OVZA 1XUDA 4GWMA 4PKVA 4R3VA 4DPEA 4PKTA 1I73A 3DTEA 5I43A 3WV2A 1JIWP 2CLTA 1DMTA 4CTHA 5CXAA
chains in the Genus database with same CATH topology
2D1NA 2W12A 3P24A 4H1QA 2TCLA 2OY2A 3DL1A 1OMJA 4FVLA 5D1SA 5BPAA 1Z3JA 1ZP5A 3DTIA 3LEAA 1JJ9A 1SU3A 3I7IA 4FXQA 3CKIA 1XFVA 3AYKA 1CXVA 2W0DA 3SHIA 3LMCA 4ZR5A 3EWJA 1G49A 1XUCA 1YP1A 3LKAA 1SLMA 3O64A 1BKCE 1JAOA 2OW0A 1C3IA 2E3XA 1HTDA 2K2GA 3KWVC 5L7FA 1D5JA 1J7NA 1S4BP 3B92A 3K7NA 3F18A 4PKRA 2X3CA 1XURA 2POJA 1D7XA 3KEKA 3GBOA 5BOYA 1ND1A 3LE9A 1H71P 2W15A 3LILA 1D8MA 1Y8JA 1QICA 3WV1A 3EDZA 1SLNA 5D1TA 4H82A 5B5OA 2OW9A 4PKSA 2X7MA 4DD8A 4FXYP 2OXWA 3OHOA 3HBVP 2J83A 3EDIA 3HY9A 1MMQA 3LGPA 3DTKA 2ERPA 5B5PA 1BZSA 4H2EA 1AF0A 3EDGA 2OI0A 1GXDA 3F15A 2MZEA 1FBLA 1MMBA 3G42A 3HY7A 3N2UA 2K9CA 2X3BA 2WO9A 4H3XA 2E2DA 2YB9A 4A3WA 5H8XA 2OW2A 1KUGA 1ZTQA 3NX7A 3L0VA 4DV8A 4G9LA 4EFSA 4L63A 1AYKA 4ON1A 2FV5A 2AIGP 4H84A 4H49A 5CZMA 1Q3AA 3UVCA 1UTTA 3G5CA 3LQBA 1R1JA 2OXUA 3P1VA 966CA 4L19A 4G0DA 2L0RA 3O2XA 1JH1A 1HFSA 2I47A 5JMYA 1KUHA 1R1IA 2DW0A 3BA0A 1HV5A 4XM6A 4AIGA 1PWWA 2PJTA 1K7IA 1QIAA 3LIRA 1UTZA 1OM7A 4J4MA 1GKDA 3ZVSA 3ZUKA 4IUWA 1XFWA 3TSKA 1A86A 1QIBA 1XFYA 1KAPP 4JP4A 1BIWA 3TVCA 4DF9A 2N8RA 3HB2P 1G05A 1ASTA 1SRPA 2J0TA 3DNGA 3ELMA 4PKUA 1G12A 3TS4A 4FU4A 1XFUA 1R1HA 3F16A 1PWQA 5I4OA 2DDFA 3V96B 1G4KA 1OS2A 1OM8A 3LJGA 4AYKA 1UMSA 1GKCA 1KUIA 2OVXA 3L0TA 3KMEA 2Z2DA 3KMCA 4I03A 3RTSA 3LUMA 1C7KA 2OW1A 1IABA 3LUNA 3KEJA 4L7AA 1QJJA 2WO8A 5I2ZA 2D1OA 2RJPA 1D8FA 1RM8A 4GWNA 4WKIA 1A85A 4HX3A 1JAQA 2KRJA 3EDHA 1USNA 1WNIA 4IJOA 2EROA 1BUDA 3VI1A 5I3MA 3KRYA 5D2BA 1HFCA 3LK8A 1I1IP 1ATLA 4QKZA 3B8ZA 3EHYA 2MLRA 2HU6A 3DPFA 1XFXA 1SMPA 1CGFA 4XM8A 1KUKA 2OZRA 1GE6A 2V4BA 1ROSA 1JIZA 1GO7P 2X3AA 2O3EA 3DSLA 3HYGA 2Y6CA 3F1AA 1BUVM 4XCTA 1PWPA 2A8HA 1GO8P 3HDBA 4IN9A 2DW2A 1EAKA 3USNA 2DDYA 2AYKA 1JANA 2JNPA 3VTGA 1BSWA 5BOTA 2Y6DA 1UMTA 4H30A 4I35A 3U1RA 1OS9A 1ZVXA 2CKIA 3HBUP 1IADA 1PWVA 3N2VA 1R54A 1JK3A 1Y0VA 1SATA 3AIGA 1O0QA 3K7LA 1CIZA 1G9KA 4H76A 4JPAA 3MA2A 4ILWD 4XBHA 1EUBA 4JIJA 1MNCA 4WK7A 3LJZA 4GR0A 1QUAA 1FLSA 1GE5A 1YQYA 4WZVA 1GE7A 4WKEA 5D7WA 5LABA 2W14A 1AKLA 1L6JA 4GQLA 1DTHA 2XS3A 3F17A 1MMPA 2OY4A 1OM6A 2OXZA 5I0LA 1UEAA 2DW1A 1IAEA 1O0TA 5D1UA 2QPJA 4PKQA 1C8TA 1FM1A 2USNA 3KHIA 2MLSA 2JT5A 1BQQM 3HDAP 3EHXA 4GR8A 4HMAA 830CA 1I76A 2YIGA 3F19A 1IACA 4Q1LA 4L6TA 1R55A 1CAQA 2ERQA 3E8RA 3KECA 2WOAA 1HOVA 2YUFA 4XM7A 1ZS0A 1OO9A 1MMRA 1HY7A 2JIHA 1KUFA 4JA1A 3LIKA 1K7GA 3DPEA 1XFZA 3B2ZA 3LJTA 1KBCA 3AYUA 4AUOA 2MZHA 3Q2GA 3I7GA 3Q2HA 4GR3A 2FV9A 3TT4A 1BQOA 1Y93A 1JKYA 1K7QA 1CQRA 1BM6A 1BKCI 5L79A 1IAGA 2JT6A 1BKCA 4GF1A 2W13A 456CA 4JQGA 2JSDA 3WV3A 1QJIA 3LQ0A 4WF6A 3OHLA 2RJQA 5I12A 4A7BA 4GUYA 1JAPA 1YCMA 2SRTA 1CK7A 1ZXVA 1CGLA 1B3DA 4AXQA 5CUHA 4PKWA 1ZXCA 1RMZA 2XS4A 2O36A 3ZXHA 2MZIA 1EB6A 3RTTA 1IAAA 1B8YA 5D3CA 1YOUA 3DWBA 1CGEA 1PWUA 2OVZA 1XUDA 4GWMA 4PKVA 4R3VA 4DPEA 4PKTA 1I73A 3DTEA 5I43A 3WV2A 1JIWP 2CLTA 1DMTA 4CTHA 5CXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D1N A;  2W12 A;  3P24 A;  4H1Q A;  2TCL A;  2OY2 A;  3DL1 A;  1OMJ A;  4FVL A;  5D1S A;  5BPA A;  1Z3J A;  1ZP5 A;  3LEA A;  1JJ9 A;  1SU3 A;  3I7I A;  4FXQ A;  3CKI A;  1XFV A;  3AYK A;  1CXV A;  2W0D A;  3SHI A;  3LMC A;  4ZR5 A;  3EWJ A;  1G49 A;  1XUC A;  1YP1 A;  3LKA A;  1SLM A;  3O64 A;  1BKC E;  1JAO A;  2OW0 A;  1C3I A;  2E3X A;  1HTD A;  2K2G A;  3KWV C;  5L7F A;  1D5J A;  1J7N A;  1S4B P;  3B92 A;  3K7N A;  3F18 A;  4PKR A;  2X3C A;  1XUR A;  2POJ A;  1D7X A;  3KEK A;  3GBO A;  5BOY A;  1ND1 A;  3LE9 A;  1H71 P;  2W15 A;  3LIL A;  1D8M A;  1Y8J A;  1QIC A;  3WV1 A;  3EDZ A;  1SLN A;  5D1T A;  4H82 A;  5B5O A;  2OW9 A;  4PKS A;  2X7M A;  4DD8 A;  4FXY P;  2OXW A;  3OHO A;  3HBV P;  2J83 A;  3EDI A;  3HY9 A;  1MMQ A;  3LGP A;  5B5P A;  2ERP A;  1BZS A;  4H2E A;  1AF0 A;  3EDG A;  2OI0 A;  1GXD A;  3F15 A;  2MZE A;  1FBL A;  1MMB A;  3G42 A;  3HY7 A;  3N2U A;  2K9C A;  2X3B A;  2WO9 A;  4H3X A;  2E2D A;  2YB9 A;  4A3W A;  5H8X A;  2OW2 A;  1KUG A;  1ZTQ A;  3NX7 A;  3L0V A;  4DV8 A;  4G9L A;  4EFS A;  4L63 A;  1AYK A;  4ON1 A;  2FV5 A;  2AIG P;  4H84 A;  4H49 A;  5CZM A;  1Q3A A;  3UVC A;  1UTT A;  3G5C A;  3LQB A;  1R1J A;  2OXU A;  3P1V A;  966C A;  4L19 A;  4G0D A;  2L0R A;  3O2X A;  1JH1 A;  1HFS A;  2I47 A;  5JMY A;  1KUH A;  1R1I A;  2DW0 A;  3BA0 A;  1HV5 A;  4XM6 A;  4AIG A;  1PWW A;  2PJT A;  1K7I A;  1QIA A;  3LIR A;  1UTZ A;  1OM7 A;  4J4M A;  1GKD A;  3ZVS A;  3ZUK A;  4IUW A;  1XFW A;  3TSK A;  1A86 A;  1QIB A;  1XFY A;  1KAP P;  4JP4 A;  1BIW A;  3TVC A;  4DF9 A;  2N8R A;  3HB2 P;  1G05 A;  1AST A;  1SRP A;  2J0T A;  3DNG A;  3ELM A;  4PKU A;  1G12 A;  3TS4 A;  4FU4 A;  1XFU A;  1R1H A;  3F16 A;  1PWQ A;  5I4O A;  2DDF A;  3V96 B;  1G4K A;  1OS2 A;  1OM8 A;  3LJG A;  4AYK A;  1UMS A;  1GKC A;  1KUI A;  2OVX A;  3L0T A;  3KME A;  2Z2D A;  3KMC A;  4I03 A;  3RTS A;  3LUM A;  1C7K A;  2OW1 A;  1IAB A;  3LUN A;  3KEJ A;  1QJJ A;  2WO8 A;  5I2Z A;  2D1O A;  2RJP A;  1D8F A;  1RM8 A;  4GWN A;  4WKI A;  1A85 A;  4HX3 A;  1JAQ A;  2KRJ A;  3EDH A;  1USN A;  1WNI A;  4IJO A;  2ERO A;  1BUD A;  3VI1 A;  5I3M A;  3KRY A;  5D2B A;  1HFC A;  3LK8 A;  1I1I P;  1ATL A;  4QKZ A;  3B8Z A;  3EHY A;  2MLR A;  2HU6 A;  3DPF A;  1XFX A;  1SMP A;  1CGF A;  4XM8 A;  1KUK A;  2OZR A;  1GE6 A;  2V4B A;  1ROS A;  1JIZ A;  1GO7 P;  2X3A A;  2O3E A;  3DSL A;  3HYG A;  2Y6C A;  3F1A A;  1BUV M;  4XCT A;  1PWP A;  2A8H A;  1GO8 P;  3HDB A;  4IN9 A;  2DW2 A;  1EAK A;  3USN A;  2DDY A;  2AYK A;  1JAN A;  2JNP A;  3VTG A;  1BSW A;  5BOT A;  2Y6D A;  1UMT A;  4H30 A;  4I35 A;  3U1R A;  1OS9 A;  1ZVX A;  2CKI A;  3HBU P;  1IAD A;  1PWV A;  3N2V A;  1R54 A;  1JK3 A;  1Y0V A;  1SAT A;  3AIG A;  1O0Q A;  3K7L A;  1CIZ A;  1G9K A;  4H76 A;  4JPA A;  3MA2 A;  4ILW D;  4XBH A;  1EUB A;  4JIJ A;  1MNC A;  4WK7 A;  3LJZ A;  4GR0 A;  1QUA A;  1FLS A;  1GE5 A;  1YQY A;  4WZV A;  1GE7 A;  4WKE A;  5D7W A;  5LAB A;  2W14 A;  1AKL A;  1L6J A;  4GQL A;  1DTH A;  2XS3 A;  3F17 A;  1MMP A;  2OY4 A;  1OM6 A;  2OXZ A;  5I0L A;  1UEA A;  2DW1 A;  1IAE A;  1O0T A;  5D1U A;  2QPJ A;  4PKQ A;  1C8T A;  1FM1 A;  2USN A;  3KHI A;  2MLS A;  2JT5 A;  1BQQ M;  3HDA P;  3EHX A;  4GR8 A;  4HMA A;  830C A;  1I76 A;  2YIG A;  3F19 A;  1IAC A;  4Q1L A;  4L6T A;  1R55 A;  1CAQ A;  2ERQ A;  3E8R A;  3KEC A;  2WOA A;  1HOV A;  4XM7 A;  1ZS0 A;  1OO9 A;  1MMR A;  1HY7 A;  2JIH A;  1KUF A;  4JA1 A;  3LIK A;  1K7G A;  3DPE A;  1XFZ A;  3B2Z A;  3LJT A;  1KBC A;  3AYU A;  4AUO A;  2MZH A;  3Q2G A;  3I7G A;  3Q2H A;  4GR3 A;  2FV9 A;  3TT4 A;  1BQO A;  1Y93 A;  1JKY A;  1K7Q A;  1CQR A;  1BM6 A;  1BKC I;  5L79 A;  1IAG A;  2JT6 A;  1BKC A;  4GF1 A;  2W13 A;  456C A;  4JQG A;  2JSD A;  3WV3 A;  1QJI A;  3LQ0 A;  4WF6 A;  3OHL A;  2RJQ A;  5I12 A;  4A7B A;  4GUY A;  1JAP A;  1YCM A;  2SRT A;  1CK7 A;  1ZXV A;  1CGL A;  1B3D A;  4AXQ A;  5CUH A;  4PKW A;  1ZXC A;  1RMZ A;  2XS4 A;  2O36 A;  3ZXH A;  2MZI A;  1EB6 A;  3RTT A;  1IAA A;  1B8Y A;  5D3C A;  1YOU A;  3DWB A;  1CGE A;  1PWU A;  2OVZ A;  1XUD A;  4GWM A;  4PKV A;  4R3V A;  4DPE A;  4PKT A;  1I73 A;  5I43 A;  3WV2 A;  1JIW P;  2CLT A;  1DMT A;  4CTH A;  5CXA A; 
#chains in the Genus database with same CATH topology
 2D1N A;  2W12 A;  3P24 A;  4H1Q A;  2TCL A;  2OY2 A;  3DL1 A;  1OMJ A;  4FVL A;  5D1S A;  5BPA A;  1Z3J A;  1ZP5 A;  3DTI A;  3LEA A;  1JJ9 A;  1SU3 A;  3I7I A;  4FXQ A;  3CKI A;  1XFV A;  3AYK A;  1CXV A;  2W0D A;  3SHI A;  3LMC A;  4ZR5 A;  3EWJ A;  1G49 A;  1XUC A;  1YP1 A;  3LKA A;  1SLM A;  3O64 A;  1BKC E;  1JAO A;  2OW0 A;  1C3I A;  2E3X A;  1HTD A;  2K2G A;  3KWV C;  5L7F A;  1D5J A;  1J7N A;  1S4B P;  3B92 A;  3K7N A;  3F18 A;  1XM5 A;  4PKR A;  2X3C A;  1XUR A;  2POJ A;  1D7X A;  3KEK A;  3GBO A;  5BOY A;  1ND1 A;  3LE9 A;  1H71 P;  2W15 A;  3LIL A;  1D8M A;  1Y8J A;  1QIC A;  3WV1 A;  3EDZ A;  1SLN A;  5D1T A;  4H82 A;  5B5O A;  2OW9 A;  4PKS A;  2X7M A;  4DD8 A;  4FXY P;  2OXW A;  3OHO A;  3HBV P;  2J83 A;  3EDI A;  3HY9 A;  1MMQ A;  3LGP A;  3DTK A;  2ERP A;  5B5P A;  1BZS A;  4H2E A;  1AF0 A;  1TVI A;  2OI0 A;  1GXD A;  3EDG A;  3F15 A;  2MZE A;  1FBL A;  1MMB A;  3G42 A;  3HY7 A;  3N2U A;  2K9C A;  2X3B A;  2WO9 A;  4H3X A;  2E2D A;  2YB9 A;  4A3W A;  5H8X A;  2OW2 A;  1KUG A;  1ZTQ A;  3NX7 A;  3L0V A;  4DV8 A;  4G9L A;  4EFS A;  4L63 A;  1AYK A;  4ON1 A;  2FV5 A;  2AIG P;  4H84 A;  4H49 A;  5CZM A;  1Q3A A;  3UVC A;  1UTT A;  3G5C A;  3LQB A;  1R1J A;  2OXU A;  3P1V A;  966C A;  4L19 A;  4G0D A;  2L0R A;  3O2X A;  1JH1 A;  1HFS A;  2I47 A;  5JMY A;  1KUH A;  1R1I A;  2DW0 A;  3BA0 A;  1HV5 A;  4XM6 A;  4AIG A;  1PWW A;  2PJT A;  1K7I A;  1QIA A;  3LIR A;  1UTZ A;  1OM7 A;  4J4M A;  1GKD A;  3ZVS A;  3ZUK A;  4IUW A;  1XFW A;  3TSK A;  1A86 A;  1QIB A;  1XFY A;  1KAP P;  4JP4 A;  1BIW A;  3TVC A;  4DF9 A;  2N8R A;  3HB2 P;  1G05 A;  1AST A;  1SRP A;  2J0T A;  3DNG A;  3ELM A;  4PKU A;  1G12 A;  3TS4 A;  4FU4 A;  1XFU A;  1R1H A;  3F16 A;  1PWQ A;  5I4O A;  2DDF A;  3V96 B;  1G4K A;  1OS2 A;  1OM8 A;  3LJG A;  4AYK A;  1UMS A;  1GKC A;  1KUI A;  2OVX A;  3L0T A;  3KME A;  2Z2D A;  3KMC A;  4I03 A;  3RTS A;  3LUM A;  1C7K A;  2OW1 A;  1IAB A;  3LUN A;  3KEJ A;  4L7A A;  1QJJ A;  2WO8 A;  5I2Z A;  2D1O A;  2RJP A;  1D8F A;  1RM8 A;  4GWN A;  4WKI A;  1A85 A;  4HX3 A;  1JAQ A;  2KRJ A;  3EDH A;  1USN A;  1WNI A;  4IJO A;  2ERO A;  1BUD A;  3VI1 A;  5I3M A;  3KRY A;  5D2B A;  1HFC A;  3LK8 A;  1I1I P;  1ATL A;  4QKZ A;  3B8Z A;  3EHY A;  2MLR A;  2HU6 A;  3DPF A;  1XFX A;  1SMP A;  1CGF A;  4XM8 A;  1KUK A;  2OZR A;  1GE6 A;  2V4B A;  1ROS A;  1JIZ A;  1GO7 P;  2X3A A;  2O3E A;  3DSL A;  3HYG A;  2Y6C A;  3F1A A;  1BUV M;  4XCT A;  1PWP A;  2A8H A;  1GO8 P;  3HDB A;  4IN9 A;  2DW2 A;  1EAK A;  1XAX A;  3USN A;  2DDY A;  2AYK A;  1JAN A;  2JNP A;  3VTG A;  1BSW A;  5BOT A;  2Y6D A;  1UMT A;  4H30 A;  4I35 A;  3U1R A;  1OS9 A;  1ZVX A;  2CKI A;  3HBU P;  1IAD A;  1PWV A;  3N2V A;  1R54 A;  1JK3 A;  1Y0V A;  1SAT A;  3AIG A;  1O0Q A;  3K7L A;  1CIZ A;  1G9K A;  4H76 A;  4JPA A;  3MA2 A;  4ILW D;  4XBH A;  1EUB A;  4JIJ A;  1MNC A;  4WK7 A;  3LJZ A;  4GR0 A;  1QUA A;  1FLS A;  1GE5 A;  1YQY A;  4WZV A;  1GE7 A;  4WKE A;  5D7W A;  5LAB A;  2W14 A;  1AKL A;  1L6J A;  4GQL A;  1DTH A;  2XS3 A;  3F17 A;  1MMP A;  2OY4 A;  1OM6 A;  2OXZ A;  5I0L A;  1UEA A;  2DW1 A;  1IAE A;  1O0T A;  5D1U A;  2QPJ A;  4PKQ A;  1C8T A;  1FM1 A;  2USN A;  3KHI A;  2MLS A;  2JT5 A;  1BQQ M;  3HDA P;  3EHX A;  4GR8 A;  4HMA A;  830C A;  1I76 A;  2YIG A;  3F19 A;  1IAC A;  4Q1L A;  4L6T A;  1R55 A;  1CAQ A;  2ERQ A;  3E8R A;  3KEC A;  2WOA A;  1HOV A;  2YUF A;  1OZ9 A;  4XM7 A;  1ZS0 A;  1OO9 A;  1MMR A;  1HY7 A;  2JIH A;  1KUF A;  4JA1 A;  3LIK A;  1K7G A;  3DPE A;  1XFZ A;  3B2Z A;  3LJT A;  1KBC A;  3AYU A;  4AUO A;  2MZH A;  3Q2G A;  3I7G A;  3Q2H A;  4GR3 A;  2FV9 A;  3TT4 A;  1BQO A;  1Y93 A;  1JKY A;  1K7Q A;  1CQR A;  1BM6 A;  1BKC I;  5L79 A;  1IAG A;  2JT6 A;  1BKC A;  4GF1 A;  2W13 A;  456C A;  4JQG A;  2JSD A;  3WV3 A;  1QJI A;  3LQ0 A;  4WF6 A;  3OHL A;  2RJQ A;  5I12 A;  4A7B A;  4GUY A;  1JAP A;  1YCM A;  2SRT A;  1CK7 A;  1ZXV A;  1CGL A;  1B3D A;  4AXQ A;  5CUH A;  4PKW A;  1ZXC A;  1RMZ A;  2XS4 A;  2O36 A;  3ZXH A;  2MZI A;  1EB6 A;  3RTT A;  1IAA A;  1B8Y A;  5D3C A;  1YOU A;  3DWB A;  1CGE A;  1PWU A;  2OVZ A;  1XUD A;  4GWM A;  4PKV A;  4R3V A;  4DPE A;  4PKT A;  1I73 A;  3DTE A;  5I43 A;  3WV2 A;  1JIW P;  2CLT A;  1DMT A;  4CTH A;  5CXA A; 
#chains in the Genus database with same CATH homology
 2D1N A;  2W12 A;  3P24 A;  4H1Q A;  2TCL A;  2OY2 A;  3DL1 A;  1OMJ A;  4FVL A;  5D1S A;  5BPA A;  1Z3J A;  1ZP5 A;  3DTI A;  3LEA A;  1JJ9 A;  1SU3 A;  3I7I A;  4FXQ A;  3CKI A;  1XFV A;  3AYK A;  1CXV A;  2W0D A;  3SHI A;  3LMC A;  4ZR5 A;  3EWJ A;  1G49 A;  1XUC A;  1YP1 A;  3LKA A;  1SLM A;  3O64 A;  1BKC E;  1JAO A;  2OW0 A;  1C3I A;  2E3X A;  1HTD A;  2K2G A;  3KWV C;  5L7F A;  1D5J A;  1J7N A;  1S4B P;  3B92 A;  3K7N A;  3F18 A;  4PKR A;  2X3C A;  1XUR A;  2POJ A;  1D7X A;  3KEK A;  3GBO A;  5BOY A;  1ND1 A;  3LE9 A;  1H71 P;  2W15 A;  3LIL A;  1D8M A;  1Y8J A;  1QIC A;  3WV1 A;  3EDZ A;  1SLN A;  5D1T A;  4H82 A;  5B5O A;  2OW9 A;  4PKS A;  2X7M A;  4DD8 A;  4FXY P;  2OXW A;  3OHO A;  3HBV P;  2J83 A;  3EDI A;  3HY9 A;  1MMQ A;  3LGP A;  3DTK A;  2ERP A;  5B5P A;  1BZS A;  4H2E A;  1AF0 A;  3EDG A;  2OI0 A;  1GXD A;  3F15 A;  2MZE A;  1FBL A;  1MMB A;  3G42 A;  3HY7 A;  3N2U A;  2K9C A;  2X3B A;  2WO9 A;  4H3X A;  2E2D A;  2YB9 A;  4A3W A;  5H8X A;  2OW2 A;  1KUG A;  1ZTQ A;  3NX7 A;  3L0V A;  4DV8 A;  4G9L A;  4EFS A;  4L63 A;  1AYK A;  4ON1 A;  2FV5 A;  2AIG P;  4H84 A;  4H49 A;  5CZM A;  1Q3A A;  3UVC A;  1UTT A;  3G5C A;  3LQB A;  1R1J A;  2OXU A;  3P1V A;  966C A;  4L19 A;  4G0D A;  2L0R A;  3O2X A;  1JH1 A;  1HFS A;  2I47 A;  5JMY A;  1KUH A;  1R1I A;  2DW0 A;  3BA0 A;  1HV5 A;  4XM6 A;  4AIG A;  1PWW A;  2PJT A;  1K7I A;  1QIA A;  3LIR A;  1UTZ A;  1OM7 A;  4J4M A;  1GKD A;  3ZVS A;  3ZUK A;  4IUW A;  1XFW A;  3TSK A;  1A86 A;  1QIB A;  1XFY A;  1KAP P;  4JP4 A;  1BIW A;  3TVC A;  4DF9 A;  2N8R A;  3HB2 P;  1G05 A;  1AST A;  1SRP A;  2J0T A;  3DNG A;  3ELM A;  4PKU A;  1G12 A;  3TS4 A;  4FU4 A;  1XFU A;  1R1H A;  3F16 A;  1PWQ A;  5I4O A;  2DDF A;  3V96 B;  1G4K A;  1OS2 A;  1OM8 A;  3LJG A;  4AYK A;  1UMS A;  1GKC A;  1KUI A;  2OVX A;  3L0T A;  3KME A;  2Z2D A;  3KMC A;  4I03 A;  3RTS A;  3LUM A;  1C7K A;  2OW1 A;  1IAB A;  3LUN A;  3KEJ A;  4L7A A;  1QJJ A;  2WO8 A;  5I2Z A;  2D1O A;  2RJP A;  1D8F A;  1RM8 A;  4GWN A;  4WKI A;  1A85 A;  4HX3 A;  1JAQ A;  2KRJ A;  3EDH A;  1USN A;  1WNI A;  4IJO A;  2ERO A;  1BUD A;  3VI1 A;  5I3M A;  3KRY A;  5D2B A;  1HFC A;  3LK8 A;  1I1I P;  1ATL A;  4QKZ A;  3B8Z A;  3EHY A;  2MLR A;  2HU6 A;  3DPF A;  1XFX A;  1SMP A;  1CGF A;  4XM8 A;  1KUK A;  2OZR A;  1GE6 A;  2V4B A;  1ROS A;  1JIZ A;  1GO7 P;  2X3A A;  2O3E A;  3DSL A;  3HYG A;  2Y6C A;  3F1A A;  1BUV M;  4XCT A;  1PWP A;  2A8H A;  1GO8 P;  3HDB A;  4IN9 A;  2DW2 A;  1EAK A;  3USN A;  2DDY A;  2AYK A;  1JAN A;  2JNP A;  3VTG A;  1BSW A;  5BOT A;  2Y6D A;  1UMT A;  4H30 A;  4I35 A;  3U1R A;  1OS9 A;  1ZVX A;  2CKI A;  3HBU P;  1IAD A;  1PWV A;  3N2V A;  1R54 A;  1JK3 A;  1Y0V A;  1SAT A;  3AIG A;  1O0Q A;  3K7L A;  1CIZ A;  1G9K A;  4H76 A;  4JPA A;  3MA2 A;  4ILW D;  4XBH A;  1EUB A;  4JIJ A;  1MNC A;  4WK7 A;  3LJZ A;  4GR0 A;  1QUA A;  1FLS A;  1GE5 A;  1YQY A;  4WZV A;  1GE7 A;  4WKE A;  5D7W A;  5LAB A;  2W14 A;  1AKL A;  1L6J A;  4GQL A;  1DTH A;  2XS3 A;  3F17 A;  1MMP A;  2OY4 A;  1OM6 A;  2OXZ A;  5I0L A;  1UEA A;  2DW1 A;  1IAE A;  1O0T A;  5D1U A;  2QPJ A;  4PKQ A;  1C8T A;  1FM1 A;  2USN A;  3KHI A;  2MLS A;  2JT5 A;  1BQQ M;  3HDA P;  3EHX A;  4GR8 A;  4HMA A;  830C A;  1I76 A;  2YIG A;  3F19 A;  1IAC A;  4Q1L A;  4L6T A;  1R55 A;  1CAQ A;  2ERQ A;  3E8R A;  3KEC A;  2WOA A;  1HOV A;  2YUF A;  4XM7 A;  1ZS0 A;  1OO9 A;  1MMR A;  1HY7 A;  2JIH A;  1KUF A;  4JA1 A;  3LIK A;  1K7G A;  3DPE A;  1XFZ A;  3B2Z A;  3LJT A;  1KBC A;  3AYU A;  4AUO A;  2MZH A;  3Q2G A;  3I7G A;  3Q2H A;  4GR3 A;  2FV9 A;  3TT4 A;  1BQO A;  1Y93 A;  1JKY A;  1K7Q A;  1CQR A;  1BM6 A;  1BKC I;  5L79 A;  1IAG A;  2JT6 A;  1BKC A;  4GF1 A;  2W13 A;  456C A;  4JQG A;  2JSD A;  3WV3 A;  1QJI A;  3LQ0 A;  4WF6 A;  3OHL A;  2RJQ A;  5I12 A;  4A7B A;  4GUY A;  1JAP A;  1YCM A;  2SRT A;  1CK7 A;  1ZXV A;  1CGL A;  1B3D A;  4AXQ A;  5CUH A;  4PKW A;  1ZXC A;  1RMZ A;  2XS4 A;  2O36 A;  3ZXH A;  2MZI A;  1EB6 A;  3RTT A;  1IAA A;  1B8Y A;  5D3C A;  1YOU A;  3DWB A;  1CGE A;  1PWU A;  2OVZ A;  1XUD A;  4GWM A;  4PKV A;  4R3V A;  4DPE A;  4PKT A;  1I73 A;  3DTE A;  5I43 A;  3WV2 A;  1JIW P;  2CLT A;  1DMT A;  4CTH A;  5CXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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