3ICUA

Protease-associated domain of the e3 ligase grail
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
171
Chain Sequence
GAMDGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PA Domain of the E3 Ligase Grail
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase RNF128
total genus 42
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02225 PA PA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 3icuA01
4P44A 3D7FA 4MCSA 4OC2A 1CX8A 3EIFA 3SJFA 1XF1A 4C8UA 4TWEA 3BI1A 4JZ0A 5D29A 3ICUA 4NGTA 3IIBA 4C99A 5IB9A 4TJXA 4C8CA 2JBKA 2PVWA 3BHXA 4CDKA 4NGRA 4JYWA 3SJGA 3FECA 2EK9A 5F09A 4OC3A 4C9RA 4OC1A 1DE4C 3SJEA 2C6PA 4OC5A 4MCPA 4P4BA 4X3RA 4NGMA 4C8TA 1Y9ZA 4KNGE 4C85A 3D7GA 4P4JA 1Z8LA 5ELYA 4C8PA 4CDJA 2C6GA 2EK8A 2XEFA 4NGNA 3KASA 3I6SA 4C8AA 3BXMA 4W9YA 3FEEA 4OC4A 3VTAA 4C9AA 3FEDA 4OMEA 4NGQA 4C84A 4P4EA 2XEGA 3BI0A 4YN3A 3RBUA 3S9NA 2C6CA 2XEIA 1V6CA 2OOTA 4C9UA 4P4IA 3SJXA 2XEJA 3S9LA 4P45A 3S9MA 3I74A 4C9VA 2JBJA 4P4DA 3FF3A 3D7HA 4LQGA 3D7DA 1WVMA 3IWWA 4NGSA 4NGPA 4C9EA 2PVVA 4MCRA 4C8FA 4OC0A 2CIJA 4TJVA 4C86A 4MCQA 2OR4A 4P4FA
chains in the Genus database with same CATH superfamily
4P44A 1CS0B 1KEEB 3D7FA 2MP0A 3TLBA 4MCSA 1EZBA 4OC2A 1EZAA 1CX8A 1DIKA 3TLYA 1JDEA 3U1BA 3EIFA 2FM4A 3EZBA 3SJFA 1XF1A 4C8UA 3GJZA 3T07A 4TWEA 2E28A 3EZEA 3BI1A 1KBLA 4JZ0A 5D29A 3ICUA 4NGTA 3IIBA 4MJXA 4C99A 2PCNA 5IB9A 4TJXA 4C8CA 2JBKA 5K99A 2PVWA 1BXRB 2OLSA 3BHXA 1VBGA 4CDKA 1C30B 3TLGA 4NGRA 4E94A 4JYWA 2AUMA 3SJGA 3FECA 2EK9A 1KC7A 5F09A 4OC3A 5FD8A 4C9RA 1GGOA 4IIYA 4OC1A 3TLGB 1DE4C 2HROA 3SJEA 2EZAA 2C6PA 4OC5A 1NXJA 4MCPA 2D0PA 4P4BA 1CE8B 4X3RA 3KRVA 1M6VB 1NBWA 4NGMA 4C8TA 1Y9ZA 4KNGE 1T36B 4C85A 4M8DA 2DIKA 3D7GA 4P4JA 1Z8LA 5ELYA 5IR2A 2C5QA 4C8PA 4CDJA 2C6GA 2EK8A 4EYSA 1VBHA 1C3OB 2HI6A 2X0SA 3SR3A 5F9MA 4H1HA 3TYXA 1ZYMA 2XEFA 4NGNA 3KASA 3I6SA 4C8AA 3C8OA 3BXMA 4W9YA 4E5SA 3FEEA 3TLEA 2EZCA 3T05A 4JVOA 2GP4A 4OC4A 5JYBA 1VI4A 3VTAA 4C9AA 3FEDA 1A9XB 4OMEA 2B0AA 4NGQA 2EZBA 2AUNA 4P4EA 2XEGA 4C84A 4IIXA 3TLCA 3BI0A 3NOJA 4CZ1A 4YN3A 2YJTA 1J3LA 3RBUA 2R82A 3S9NA 2C6CA 2XEIA 1R61A 1V6CA 1ZRSA 2OOTA 2HWGA 4MI1A 4INJA 4P4IA 3SJXA 2XEJA 3TLAA 3TLZA 4C9UA 4COGA 5JVLA 4P45A 3EZAA 3S9MA 3S9LA 3I74A 4C9VA 5F1YA 4J0NA 2JBJA 4P4DA 2D0OA 5F5XA 3FF3A 3G23A 3D7HA 4LQGA 1Q5XA 3D7DA 3T5MA 1WVMA 3IWWA 4NGSA 1ZL0A 4CO9A 4NGPA 4C9EA 2YJVA 2PVVA 4COBA 3K9TA 4MCRA 4OC0A 4C8FA 2CIJA 4TJVA 3T0TA 1JDBC 4C86A 4MCQA 2OR4A 3K4IA 4P4FA
chains in the Genus database with same CATH topology
4P44A 3D7FA 4MCSA 4OC2A 1CX8A 3EIFA 3SJFA 1XF1A 4C8UA 4TWEA 3BI1A 4JZ0A 5D29A 3ICUA 4NGTA 3IIBA 4C99A 5IB9A 4TJXA 4C8CA 2JBKA 2PVWA 3BHXA 4CDKA 4NGRA 4JYWA 3SJGA 3FECA 2EK9A 5F09A 4OC3A 4C9RA 4OC1A 1DE4C 3SJEA 2C6PA 4OC5A 4MCPA 4P4BA 4X3RA 4NGMA 4C8TA 1Y9ZA 4KNGE 4C85A 3D7GA 4P4JA 1Z8LA 5ELYA 5IR2A 2C5QA 4C8PA 4CDJA 2C6GA 2EK8A 2XEFA 4NGNA 3KASA 3I6SA 4C8AA 3BXMA 4W9YA 3FEEA 2GP4A 4OC4A 3VTAA 4C9AA 3FEDA 4OMEA 4NGQA 4C84A 4P4EA 2XEGA 3BI0A 4YN3A 3RBUA 3S9NA 2C6CA 2XEIA 1V6CA 2OOTA 4C9UA 4P4IA 3SJXA 2XEJA 3S9LA 4P45A 3S9MA 3I74A 4C9VA 2JBJA 4P4DA 3FF3A 3D7HA 4LQGA 3D7DA 1WVMA 3IWWA 4NGSA 4NGPA 4C9EA 2PVVA 3K9TA 4MCRA 4OC0A 4C8FA 2CIJA 4TJVA 4C86A 4MCQA 2OR4A 4P4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P44 A;  3D7F A;  4MCS A;  4OC2 A;  1CX8 A;  3EIF A;  3SJF A;  1XF1 A;  4C8U A;  4TWE A;  3BI1 A;  4JZ0 A;  5D29 A;  3ICU A;  4NGT A;  3IIB A;  4C99 A;  5IB9 A;  4TJX A;  4C8C A;  2JBK A;  2PVW A;  3BHX A;  4CDK A;  4NGR A;  4JYW A;  3SJG A;  3FEC A;  2EK9 A;  5F09 A;  4OC3 A;  4C9R A;  4OC1 A;  1DE4 C;  3SJE A;  2C6P A;  4OC5 A;  4MCP A;  4P4B A;  4X3R A;  4NGM A;  4C8T A;  1Y9Z A;  4KNG E;  4C85 A;  3D7G A;  4P4J A;  1Z8L A;  5ELY A;  4C8P A;  4CDJ A;  2C6G A;  2EK8 A;  2XEF A;  4NGN A;  3KAS A;  3I6S A;  4C8A A;  3BXM A;  4W9Y A;  3FEE A;  4OC4 A;  3VTA A;  4C9A A;  3FED A;  4OME A;  4NGQ A;  4C84 A;  4P4E A;  2XEG A;  3BI0 A;  4YN3 A;  3RBU A;  3S9N A;  2C6C A;  2XEI A;  1V6C A;  2OOT A;  4C9U A;  4P4I A;  3SJX A;  2XEJ A;  3S9L A;  4P45 A;  3S9M A;  3I74 A;  4C9V A;  2JBJ A;  4P4D A;  3FF3 A;  3D7H A;  4LQG A;  3D7D A;  1WVM A;  3IWW A;  4NGS A;  4NGP A;  4C9E A;  2PVV A;  4MCR A;  4C8F A;  4OC0 A;  2CIJ A;  4TJV A;  4C86 A;  4MCQ A;  2OR4 A;  4P4F A; 
#chains in the Genus database with same CATH topology
 4P44 A;  1CS0 B;  1KEE B;  3D7F A;  2MP0 A;  3TLB A;  4MCS A;  1EZB A;  4OC2 A;  1EZA A;  1CX8 A;  1DIK A;  3TLY A;  1JDE A;  3U1B A;  3EIF A;  2FM4 A;  3EZB A;  3SJF A;  1XF1 A;  4C8U A;  3GJZ A;  3T07 A;  4TWE A;  2E28 A;  3EZE A;  3BI1 A;  1KBL A;  4JZ0 A;  5D29 A;  3ICU A;  4NGT A;  3IIB A;  4MJX A;  4C99 A;  2PCN A;  5IB9 A;  4TJX A;  4C8C A;  2JBK A;  5K99 A;  2PVW A;  1BXR B;  2OLS A;  3BHX A;  1VBG A;  4CDK A;  1C30 B;  3TLG A;  4NGR A;  4E94 A;  4JYW A;  2AUM A;  3SJG A;  3FEC A;  2EK9 A;  1KC7 A;  5F09 A;  4OC3 A;  5FD8 A;  4C9R A;  1GGO A;  4IIY A;  4OC1 A;  3TLG B;  1DE4 C;  2HRO A;  3SJE A;  2EZA A;  2C6P A;  4OC5 A;  1NXJ A;  4MCP A;  2D0P A;  4P4B A;  1CE8 B;  4X3R A;  3KRV A;  1M6V B;  1NBW A;  4NGM A;  4C8T A;  1Y9Z A;  4KNG E;  1T36 B;  4C85 A;  4M8D A;  2DIK A;  3D7G A;  4P4J A;  1Z8L A;  5ELY A;  5IR2 A;  2C5Q A;  4C8P A;  4CDJ A;  2C6G A;  2EK8 A;  4EYS A;  1VBH A;  1C3O B;  2HI6 A;  2X0S A;  3SR3 A;  5F9M A;  4H1H A;  3TYX A;  1ZYM A;  2XEF A;  4NGN A;  3KAS A;  3I6S A;  4C8A A;  3C8O A;  3BXM A;  4W9Y A;  4E5S A;  3FEE A;  3TLE A;  2EZC A;  3T05 A;  4JVO A;  2GP4 A;  4OC4 A;  5JYB A;  1VI4 A;  3VTA A;  4C9A A;  3FED A;  1A9X B;  4OME A;  2B0A A;  4NGQ A;  2EZB A;  2AUN A;  4P4E A;  2XEG A;  4C84 A;  4IIX A;  3TLC A;  3BI0 A;  3NOJ A;  4CZ1 A;  4YN3 A;  2YJT A;  1J3L A;  3RBU A;  2R82 A;  3S9N A;  2C6C A;  2XEI A;  1R61 A;  1V6C A;  1ZRS A;  2OOT A;  2HWG A;  4MI1 A;  4INJ A;  4P4I A;  3SJX A;  2XEJ A;  3TLA A;  3TLZ A;  4C9U A;  4COG A;  5JVL A;  4P45 A;  3EZA A;  3S9M A;  3S9L A;  3I74 A;  4C9V A;  5F1Y A;  4J0N A;  2JBJ A;  4P4D A;  2D0O A;  5F5X A;  3FF3 A;  3G23 A;  3D7H A;  4LQG A;  1Q5X A;  3D7D A;  3T5M A;  1WVM A;  3IWW A;  4NGS A;  1ZL0 A;  4CO9 A;  4NGP A;  4C9E A;  2YJV A;  2PVV A;  4COB A;  3K9T A;  4MCR A;  4OC0 A;  4C8F A;  2CIJ A;  4TJV A;  3T0T A;  1JDB C;  4C86 A;  4MCQ A;  2OR4 A;  3K4I A;  4P4F A; 
#chains in the Genus database with same CATH homology
 4P44 A;  3D7F A;  4MCS A;  4OC2 A;  1CX8 A;  3EIF A;  3SJF A;  1XF1 A;  4C8U A;  4TWE A;  3BI1 A;  4JZ0 A;  5D29 A;  3ICU A;  4NGT A;  3IIB A;  4C99 A;  5IB9 A;  4TJX A;  4C8C A;  2JBK A;  2PVW A;  3BHX A;  4CDK A;  4NGR A;  4JYW A;  3SJG A;  3FEC A;  2EK9 A;  5F09 A;  4OC3 A;  4C9R A;  4OC1 A;  1DE4 C;  3SJE A;  2C6P A;  4OC5 A;  4MCP A;  4P4B A;  4X3R A;  4NGM A;  4C8T A;  1Y9Z A;  4KNG E;  4C85 A;  3D7G A;  4P4J A;  1Z8L A;  5ELY A;  5IR2 A;  2C5Q A;  4C8P A;  4CDJ A;  2C6G A;  2EK8 A;  2XEF A;  4NGN A;  3KAS A;  3I6S A;  4C8A A;  3BXM A;  4W9Y A;  3FEE A;  2GP4 A;  4OC4 A;  3VTA A;  4C9A A;  3FED A;  4OME A;  4NGQ A;  4C84 A;  4P4E A;  2XEG A;  3BI0 A;  4YN3 A;  3RBU A;  3S9N A;  2C6C A;  2XEI A;  1V6C A;  2OOT A;  4C9U A;  4P4I A;  3SJX A;  2XEJ A;  3S9L A;  4P45 A;  3S9M A;  3I74 A;  4C9V A;  2JBJ A;  4P4D A;  3FF3 A;  3D7H A;  4LQG A;  3D7D A;  1WVM A;  3IWW A;  4NGS A;  4NGP A;  4C9E A;  2PVV A;  3K9T A;  4MCR A;  4OC0 A;  4C8F A;  2CIJ A;  4TJV A;  4C86 A;  4MCQ A;  2OR4 A;  4P4F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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