3IGZB

Crystal structures of leishmania mexicana phosphoglycerate mutase at low cobalt concentration
Total Genus 207
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
Knots found
sequence length
549
structure length
549
Chain Sequence
LLLKPHKDLPRRTVLIVVMDGLGIGPEDDYDAVHMASTPFMDAHRRDNRHFRCVRAHGTAVGLPTDADMGNSEVGHNALGAGRVALQGASLVDDAIKSGEIYTGEGYRYLHGAFSKEGSTLHLIGLLSDGGVHSRDNQIYSIIEHAVKDGAKRIRVHALYDGRDVPDGSSFRFTDELEAVLAKVRQNGCDAAIASGGGRMFVTMDRYDADWSIVERGWRAQVLGDARHFHSAKEAITTFREEDPKVTDQYYPPFIVVDEQDKPLGTIEDGDAVLCVNFRGDRVIEMTRAFEDEDFNKFDRVRVPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRVSEEYLCGSGLNIFACSETQKFGHVTYFWNGNRSGKIDEKHETFKEVPSDRVQFNEKPRMQSAAITEAAIEALKSGMYNVVRINFPNGDMVGHTGDLKATITGVEAVDESLAKLKDAVDSVNGVYIVTADHGNSDDMAQRDKKGKPMKDGNGNVLPLTSHTLSPVPVFIGGAGLDPRVAMRTDLPAAGLANVTATFINLLGFEAPEDYEPSLIYVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Cofactor-independent phosphoglycerate mutase
publication title Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclass
pubmed doi rcsb
source organism Leishmania mexicana
molecule tags Isomerase
total genus 207
structure length 549
sequence length 549
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2009-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01676 Metalloenzyme Metalloenzyme superfamily
B PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3igzB01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3igzB02
3T01A 3DPCA 3NKNA 1ALIA 1KH9A 3UO0A 5IJSA 5LIAA 5L0EA 4YR1A 4GTWA 1ANJA 2VQRA 2W8DA 5GRRA 4ZG9A 1ANIA 2W5TA 3E2DA 4KAVA 4ZG7A 5HRTA 3WAYA 3M7VA 3WAWA 4MHXA 1ED8A 2QZUA 3NVLA 1ELXA 3LXQA 4GTZA 3KD8A 1N2LA 1EJJA 3ED4A 4CXKA 1KHJA 1E3CP 2W5RA 4UOOA 4UORA 3T02A 2W5XA 1SHNA 1KHLA 1AJCA 2W8SA 4ZGAA 2GSOA 1ZEBA 1KHKA 3BDFA 1KH5A 1B8JA 1P49A 4KM4A 5EGHA 3MK0A 3B5QA 2RH6A 4QAXA 1Y7AA 1FSUA 1ALKA 2XRGA 3UNYA 4NWXA 4ZG6A 3NKRA 4UOPA 1Y6VA 1ELYA 1HDHA 1ALHA 4LR2A 2IUCB 3WAXA 3CMRA 2GSNA 1HQAA 2W5SA 5TJ3A 4LR7A 3M8WA 2W5QA 3WBHA 1EW9A 1O98A 4N7TA 4B56A 1ED9A 4KJDA 2GSUA 3NKOA 3TG0A 3MK2A 4GTXA 4LRBA 2XR9A 5LQQA 1URAA 2G9YA 3BDGB 5DLVA 2ZKTA 4KJGA 5C66A 1SHQA 1E33P 3UN2A 4CYSA 4KAYA 2ANHA 3T00A 1O99A 5AJ9A 3SZZA 3NKPA 5L0BA 5DLWA 1E2SP 2W5VA 1AJDA 4MY4A 1AJBA 5LRNA 4TN0A 3NKQA 5K4PA 4FDJA 2W5WA 1HJKA 4LRDA 1AUKA 3UN5A 4LRFA 4UPHA 4UPLA 3BDHA 4LREA 1N2KA 3DYCA 5DLTA 2IUCA 1ZEDA 4MIVA 1ZEFA 4UPKA 5IJQA 3OT9A 3TWZA 2D1GA 1EQJA 3Q3QA 3IGYB 1AJAA 4LRAA 5INHA 4CYRA 1EI6A 2GLQA 2GA3A 2X98A 3A52A 5KXAA 3IDDA 1EW8A 5EGEA 1E1ZP 3BDGA 3M8ZA 4UPIA 4LR8A 4LQYA 3UN3A 3SZYA 4CXSA 3M8YA 4NWJA 1KH7A 1ELZA 1KHNA 3IGZB 4LR9A 5L0KA 3TX0A 4GTYA 2IFYA 1EW2A 1KH4A 5LRMA 3WAVA 3NKMA 4FDIA 4CXUA 5GOVA 1K7HA 1ALJA 1URBA 3MK1A 4LRCA
chains in the Genus database with same CATH superfamily
3T01A 3DPCA 3NKNA 1ALIA 1KH9A 3UO0A 5IJSA 5LIAA 5L0EA 4YR1A 4GTWA 1ANJA 2VQRA 2W8DA 5GRRA 4ZG9A 1ANIA 2W5TA 3E2DA 4KAVA 4ZG7A 5HRTA 3WAYA 3M7VA 3WAWA 4MHXA 1ED8A 2QZUA 3NVLA 1ELXA 3LXQA 4GTZA 3KD8A 1N2LA 1EJJA 3ED4A 4CXKA 1KHJA 1E3CP 2W5RA 4UOOA 4UORA 3T02A 2W5XA 1SHNA 1KHLA 1AJCA 2W8SA 4ZGAA 2GSOA 1ZEBA 1KHKA 3BDFA 1KH5A 1B8JA 1P49A 4KM4A 5EGHA 3MK0A 3B5QA 2RH6A 4QAXA 1Y7AA 1FSUA 1ALKA 2XRGA 3UNYA 4NWXA 4ZG6A 3NKRA 4UOPA 1Y6VA 1ELYA 1HDHA 1ALHA 4LR2A 2IUCB 3WAXA 3CMRA 2GSNA 1HQAA 2W5SA 5TJ3A 4LR7A 3M8WA 2W5QA 3WBHA 1EW9A 1O98A 4N7TA 4B56A 1ED9A 4KJDA 2GSUA 3NKOA 3TG0A 3MK2A 4GTXA 4LRBA 2XR9A 5LQQA 1URAA 2G9YA 3BDGB 5DLVA 2ZKTA 4KJGA 5C66A 1SHQA 1E33P 3UN2A 4CYSA 4KAYA 2ANHA 3T00A 1O99A 5AJ9A 3SZZA 3NKPA 5L0BA 5DLWA 1E2SP 2W5VA 1AJDA 4MY4A 1AJBA 5LRNA 4TN0A 3NKQA 5K4PA 4FDJA 2W5WA 1HJKA 4LRDA 1AUKA 3UN5A 4LRFA 4UPHA 4UPLA 3BDHA 4LREA 1N2KA 3DYCA 5DLTA 2IUCA 1ZEDA 4MIVA 1ZEFA 4UPKA 5IJQA 3OT9A 3TWZA 2D1GA 1EQJA 3Q3QA 3IGYB 1AJAA 4LRAA 5INHA 4CYRA 1EI6A 2GLQA 2GA3A 2X98A 3A52A 5KXAA 3IDDA 1EW8A 5EGEA 1E1ZP 3BDGA 3M8ZA 4UPIA 4LR8A 4LQYA 3UN3A 3SZYA 4CXSA 3M8YA 4NWJA 1KH7A 1ELZA 1KHNA 3IGZB 4LR9A 5L0KA 3TX0A 4GTYA 2IFYA 1EW2A 1KH4A 5LRMA 3WAVA 3NKMA 4FDIA 4CXUA 5GOVA 1K7HA 1ALJA 1URBA 3MK1A 4LRCA
chains in the Genus database with same CATH topology
3T01A 3DPCA 3NKNA 1ALIA 1KH9A 3UO0A 5IJSA 5LIAA 5L0EA 4YR1A 4GTWA 1ANJA 2VQRA 2W8DA 5GRRA 4ZG9A 1ANIA 2W5TA 3E2DA 4KAVA 4ZG7A 5HRTA 3WAYA 3M7VA 3WAWA 4MHXA 1ED8A 2QZUA 3NVLA 1ELXA 3LXQA 4GTZA 3KD8A 1N2LA 1EJJA 3ED4A 4CXKA 1KHJA 1E3CP 2W5RA 4UOOA 4UORA 3T02A 2W5XA 1SHNA 1KHLA 1AJCA 2W8SA 4ZGAA 2GSOA 1ZEBA 1KHKA 3BDFA 1KH5A 1B8JA 1P49A 4KM4A 5EGHA 3MK0A 3B5QA 2RH6A 4QAXA 1Y7AA 1FSUA 1ALKA 2XRGA 3UNYA 4NWXA 4ZG6A 3NKRA 4UOPA 1Y6VA 1ELYA 1HDHA 1ALHA 4LR2A 2IUCB 3WAXA 3CMRA 2GSNA 1HQAA 2W5SA 5TJ3A 4LR7A 3M8WA 2W5QA 3WBHA 1EW9A 1O98A 4N7TA 4B56A 1ED9A 4KJDA 2GSUA 3NKOA 3TG0A 3MK2A 4GTXA 4LRBA 2XR9A 5LQQA 1URAA 2G9YA 3BDGB 5DLVA 2ZKTA 4KJGA 5C66A 1SHQA 1E33P 3UN2A 4CYSA 4KAYA 2ANHA 3T00A 1O99A 5AJ9A 3SZZA 3NKPA 5L0BA 5DLWA 1E2SP 2W5VA 1AJDA 4MY4A 1AJBA 5LRNA 4TN0A 3NKQA 5K4PA 4FDJA 2W5WA 1HJKA 4LRDA 1AUKA 3UN5A 4LRFA 4UPHA 4UPLA 3BDHA 4LREA 1N2KA 3DYCA 5DLTA 2IUCA 1ZEDA 4MIVA 1ZEFA 4UPKA 5IJQA 3OT9A 3TWZA 2D1GA 1EQJA 3Q3QA 3IGYB 1AJAA 4LRAA 5INHA 4CYRA 1EI6A 2GLQA 2GA3A 2X98A 3A52A 5KXAA 3IDDA 1EW8A 5EGEA 1E1ZP 3BDGA 3M8ZA 4UPIA 4LR8A 4LQYA 3UN3A 3SZYA 4CXSA 3M8YA 4NWJA 1KH7A 1ELZA 1KHNA 3IGZB 4LR9A 5L0KA 3TX0A 4GTYA 2IFYA 1EW2A 1KH4A 5LRMA 3WAVA 3NKMA 4FDIA 4CXUA 5GOVA 1K7HA 1ALJA 1URBA 3MK1A 4LRCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T01 A;  3DPC A;  3NKN A;  1ALI A;  1KH9 A;  3UO0 A;  5IJS A;  5LIA A;  5L0E A;  4YR1 A;  4GTW A;  1ANJ A;  2VQR A;  2W8D A;  5GRR A;  4ZG9 A;  1ANI A;  2W5T A;  3E2D A;  4KAV A;  4ZG7 A;  5HRT A;  3WAY A;  3M7V A;  3WAW A;  4MHX A;  1ED8 A;  2QZU A;  3NVL A;  1ELX A;  3LXQ A;  4GTZ A;  3KD8 A;  1N2L A;  1EJJ A;  3ED4 A;  4CXK A;  1KHJ A;  1E3C P;  2W5R A;  4UOO A;  4UOR A;  3T02 A;  2W5X A;  1SHN A;  1KHL A;  1AJC A;  2W8S A;  4ZGA A;  2GSO A;  1ZEB A;  1KHK A;  3BDF A;  1KH5 A;  1B8J A;  1P49 A;  4KM4 A;  5EGH A;  3MK0 A;  3B5Q A;  2RH6 A;  4QAX A;  1Y7A A;  1FSU A;  1ALK A;  2XRG A;  3UNY A;  4NWX A;  4ZG6 A;  3NKR A;  4UOP A;  1Y6V A;  1ELY A;  1HDH A;  1ALH A;  4LR2 A;  2IUC B;  3WAX A;  3CMR A;  2GSN A;  1HQA A;  2W5S A;  5TJ3 A;  4LR7 A;  3M8W A;  2W5Q A;  3WBH A;  1EW9 A;  1O98 A;  4N7T A;  4B56 A;  1ED9 A;  4KJD A;  2GSU A;  3NKO A;  3TG0 A;  3MK2 A;  4GTX A;  4LRB A;  2XR9 A;  5LQQ A;  1URA A;  2G9Y A;  3BDG B;  5DLV A;  2ZKT A;  4KJG A;  5C66 A;  1SHQ A;  1E33 P;  3UN2 A;  4CYS A;  4KAY A;  2ANH A;  3T00 A;  1O99 A;  5AJ9 A;  3SZZ A;  3NKP A;  5L0B A;  5DLW A;  1E2S P;  2W5V A;  1AJD A;  4MY4 A;  1AJB A;  5LRN A;  4TN0 A;  3NKQ A;  5K4P A;  4FDJ A;  2W5W A;  1HJK A;  4LRD A;  1AUK A;  3UN5 A;  4LRF A;  4UPH A;  4UPL A;  3BDH A;  4LRE A;  1N2K A;  3DYC A;  5DLT A;  2IUC A;  1ZED A;  4MIV A;  1ZEF A;  4UPK A;  5IJQ A;  3OT9 A;  3TWZ A;  2D1G A;  1EQJ A;  3Q3Q A;  3IGY B;  1AJA A;  4LRA A;  5INH A;  4CYR A;  1EI6 A;  2GLQ A;  2GA3 A;  2X98 A;  3A52 A;  5KXA A;  3IDD A;  1EW8 A;  5EGE A;  1E1Z P;  3BDG A;  3M8Z A;  4UPI A;  4LR8 A;  4LQY A;  3UN3 A;  3SZY A;  4CXS A;  3M8Y A;  4NWJ A;  1KH7 A;  1ELZ A;  1KHN A;  3IGZ B;  4LR9 A;  5L0K A;  3TX0 A;  4GTY A;  2IFY A;  1EW2 A;  1KH4 A;  5LRM A;  3WAV A;  3NKM A;  4FDI A;  4CXU A;  5GOV A;  1K7H A;  1ALJ A;  1URB A;  3MK1 A;  4LRC A; 
#chains in the Genus database with same CATH topology
 3T01 A;  3DPC A;  3NKN A;  1ALI A;  1KH9 A;  3UO0 A;  5IJS A;  5LIA A;  5L0E A;  4YR1 A;  4GTW A;  1ANJ A;  2VQR A;  2W8D A;  5GRR A;  4ZG9 A;  1ANI A;  2W5T A;  3E2D A;  4KAV A;  4ZG7 A;  5HRT A;  3WAY A;  3M7V A;  3WAW A;  4MHX A;  1ED8 A;  2QZU A;  3NVL A;  1ELX A;  3LXQ A;  4GTZ A;  3KD8 A;  1N2L A;  1EJJ A;  3ED4 A;  4CXK A;  1KHJ A;  1E3C P;  2W5R A;  4UOO A;  4UOR A;  3T02 A;  2W5X A;  1SHN A;  1KHL A;  1AJC A;  2W8S A;  4ZGA A;  2GSO A;  1ZEB A;  1KHK A;  3BDF A;  1KH5 A;  1B8J A;  1P49 A;  4KM4 A;  5EGH A;  3MK0 A;  3B5Q A;  2RH6 A;  4QAX A;  1Y7A A;  1FSU A;  1ALK A;  2XRG A;  3UNY A;  4NWX A;  4ZG6 A;  3NKR A;  4UOP A;  1Y6V A;  1ELY A;  1HDH A;  1ALH A;  4LR2 A;  2IUC B;  3WAX A;  3CMR A;  2GSN A;  1HQA A;  2W5S A;  5TJ3 A;  4LR7 A;  3M8W A;  2W5Q A;  3WBH A;  1EW9 A;  1O98 A;  4N7T A;  4B56 A;  1ED9 A;  4KJD A;  2GSU A;  3NKO A;  3TG0 A;  3MK2 A;  4GTX A;  4LRB A;  2XR9 A;  5LQQ A;  1URA A;  2G9Y A;  3BDG B;  5DLV A;  2ZKT A;  4KJG A;  5C66 A;  1SHQ A;  1E33 P;  3UN2 A;  4CYS A;  4KAY A;  2ANH A;  3T00 A;  1O99 A;  5AJ9 A;  3SZZ A;  3NKP A;  5L0B A;  5DLW A;  1E2S P;  2W5V A;  1AJD A;  4MY4 A;  1AJB A;  5LRN A;  4TN0 A;  3NKQ A;  5K4P A;  4FDJ A;  2W5W A;  1HJK A;  4LRD A;  1AUK A;  3UN5 A;  4LRF A;  4UPH A;  4UPL A;  3BDH A;  4LRE A;  1N2K A;  3DYC A;  5DLT A;  2IUC A;  1ZED A;  4MIV A;  1ZEF A;  4UPK A;  5IJQ A;  3OT9 A;  3TWZ A;  2D1G A;  1EQJ A;  3Q3Q A;  3IGY B;  1AJA A;  4LRA A;  5INH A;  4CYR A;  1EI6 A;  2GLQ A;  2GA3 A;  2X98 A;  3A52 A;  5KXA A;  3IDD A;  1EW8 A;  5EGE A;  1E1Z P;  3BDG A;  3M8Z A;  4UPI A;  4LR8 A;  4LQY A;  3UN3 A;  3SZY A;  4CXS A;  3M8Y A;  4NWJ A;  1KH7 A;  1ELZ A;  1KHN A;  3IGZ B;  4LR9 A;  5L0K A;  3TX0 A;  4GTY A;  2IFY A;  1EW2 A;  1KH4 A;  5LRM A;  3WAV A;  3NKM A;  4FDI A;  4CXU A;  5GOV A;  1K7H A;  1ALJ A;  1URB A;  3MK1 A;  4LRC A; 
#chains in the Genus database with same CATH homology
 3T01 A;  3DPC A;  3NKN A;  1ALI A;  1KH9 A;  3UO0 A;  5IJS A;  5LIA A;  5L0E A;  4YR1 A;  4GTW A;  1ANJ A;  2VQR A;  2W8D A;  5GRR A;  4ZG9 A;  1ANI A;  2W5T A;  3E2D A;  4KAV A;  4ZG7 A;  5HRT A;  3WAY A;  3M7V A;  3WAW A;  4MHX A;  1ED8 A;  2QZU A;  3NVL A;  1ELX A;  3LXQ A;  4GTZ A;  3KD8 A;  1N2L A;  1EJJ A;  3ED4 A;  4CXK A;  1KHJ A;  1E3C P;  2W5R A;  4UOO A;  4UOR A;  3T02 A;  2W5X A;  1SHN A;  1KHL A;  1AJC A;  2W8S A;  4ZGA A;  2GSO A;  1ZEB A;  1KHK A;  3BDF A;  1KH5 A;  1B8J A;  1P49 A;  4KM4 A;  5EGH A;  3MK0 A;  3B5Q A;  2RH6 A;  4QAX A;  1Y7A A;  1FSU A;  1ALK A;  2XRG A;  3UNY A;  4NWX A;  4ZG6 A;  3NKR A;  4UOP A;  1Y6V A;  1ELY A;  1HDH A;  1ALH A;  4LR2 A;  2IUC B;  3WAX A;  3CMR A;  2GSN A;  1HQA A;  2W5S A;  5TJ3 A;  4LR7 A;  3M8W A;  2W5Q A;  3WBH A;  1EW9 A;  1O98 A;  4N7T A;  4B56 A;  1ED9 A;  4KJD A;  2GSU A;  3NKO A;  3TG0 A;  3MK2 A;  4GTX A;  4LRB A;  2XR9 A;  5LQQ A;  1URA A;  2G9Y A;  3BDG B;  5DLV A;  2ZKT A;  4KJG A;  5C66 A;  1SHQ A;  1E33 P;  3UN2 A;  4CYS A;  4KAY A;  2ANH A;  3T00 A;  1O99 A;  5AJ9 A;  3SZZ A;  3NKP A;  5L0B A;  5DLW A;  1E2S P;  2W5V A;  1AJD A;  4MY4 A;  1AJB A;  5LRN A;  4TN0 A;  3NKQ A;  5K4P A;  4FDJ A;  2W5W A;  1HJK A;  4LRD A;  1AUK A;  3UN5 A;  4LRF A;  4UPH A;  4UPL A;  3BDH A;  4LRE A;  1N2K A;  3DYC A;  5DLT A;  2IUC A;  1ZED A;  4MIV A;  1ZEF A;  4UPK A;  5IJQ A;  3OT9 A;  3TWZ A;  2D1G A;  1EQJ A;  3Q3Q A;  3IGY B;  1AJA A;  4LRA A;  5INH A;  4CYR A;  1EI6 A;  2GLQ A;  2GA3 A;  2X98 A;  3A52 A;  5KXA A;  3IDD A;  1EW8 A;  5EGE A;  1E1Z P;  3BDG A;  3M8Z A;  4UPI A;  4LR8 A;  4LQY A;  3UN3 A;  3SZY A;  4CXS A;  3M8Y A;  4NWJ A;  1KH7 A;  1ELZ A;  1KHN A;  3IGZ B;  4LR9 A;  5L0K A;  3TX0 A;  4GTY A;  2IFY A;  1EW2 A;  1KH4 A;  5LRM A;  3WAV A;  3NKM A;  4FDI A;  4CXU A;  5GOV A;  1K7H A;  1ALJ A;  1URB A;  3MK1 A;  4LRC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...