3IGZB

Crystal structures of leishmania mexicana phosphoglycerate mutase at low cobalt concentration
Total Genus 207
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
207
Knots found
sequence length
549
structure length
549
Chain Sequence
b'LLLKPHKDLPRRTVLIVVMDGLGIGPEDDYDAVHMASTPFMDAHRRDNRHFRCVRAHGTAVGLPTDADMGNSEVGHNALGAGRVALQGASLVDDAIKSGEIYTGEGYRYLHGAFSKEGSTLHLIGLLSDGGVHSRDNQIYSIIEHAVKDGAKRIRVHALYDGRDVPDGSSFRFTDELEAVLAKVRQNGCDAAIASGGGRMFVTMDRYDADWSIVERGWRAQVLGDARHFHSAKEAITTFREEDPKVTDQYYPPFIVVDEQDKPLGTIEDGDAVLCVNFRGDRVIEMTRAFEDEDFNKFDRVRVPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRVSEEYLCGSGLNIFACSETQKFGHVTYFWNGNRSGKIDEKHETFKEVPSDRVQFNEKPRMQSAAITEAAIEALKSGMYNVVRINFPNGDMVGHTGDLKATITGVEAVDESLAKLKDAVDSVNGVYIVTADHGNSDDMAQRDKKGKPMKDGNGNVLPLTSHTLSPVPVFIGGAGLDPRVAMRTDLPAAGLANVTATFINLLGFEAPEDYEPSLIYVE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Cofactor-independent phosphoglycerate mutase
publication title Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclass
pubmed doi rcsb
source organism Leishmania mexicana
molecule tags Isomerase
total genus 207
structure length 549
sequence length 549
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2009-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01676 Metalloenzyme Metalloenzyme superfamily
B PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3igzB01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3igzB02
1AJDA 1SHNA 2GA3A 1ALIA 1ZEDA 1KH5A 4UOPA 1URAA 4CXUA 4N7TA 4LR7A 1N2KA 3UNYA 3A52A 3M8WA 2IUCA 2IFYA 4TN0A 5KXAA 1KHJA 2W5QA 5L0EA 1AJCA 2G9YA 4NWXA 4ZG9A 2VQRA 1ALKA 2W5RA 3MK1A 1ANIA 1EW8A 3LXQA 4GTZA 3WAVA 5LIAA 4KAYA 1KHKA 5AJ9A 1ED8A 2ZKTA 4FDIA 5EGEA 1E33P 1AJAA 2XRGA 2W8SA 4KAVA 5DLVA 3NKPA 5LQQA 1HJKA 1EW9A 1ALHA 3WBHA 4LRFA 3MK2A 5TJ3A 4LR8A 1ED9A 3T02A 3NKQA 1KH7A 4B56A 1B8JA 1Y7AA 2W5SA 3NVLA 5GOVA 4CYRA 4LREA 1ELZA 2GLQA 3E2DA 2RH6A 3TX0A 2W5TA 2W5VA 3M7VA 5HRTA 3BDGA 3KD8A 3NKMA 5DLTA 3ED4A 1KH4A 1SHQA 3IGZB 4GTYA 1K7HA 4UPKA 2GSUA 1EJJA 4KM4A 1ALJA 4UPHA 4LRDA 3WAXA 5C66A 4MIVA 5LRNA 3DYCA 4MY4A 1ZEFA 4LRCA 4UORA 1EQJA 1Y6VA 3B5QA 1ELYA 3DPCA 1ZEBA 3NKRA 5GRRA 4GTWA 1AJBA 5LRMA 3OT9A 5IJQA 1ANJA 5EGHA 4LRBA 3NKNA 3M8ZA 1HQAA 4FDJA 4LR9A 4LRAA 5INHA 3TWZA 2W5WA 3M8YA 3SZYA 1EW2A 3UN3A 1E2SP 1E3CP 1ELXA 4KJGA 2ANHA 3MK0A 3Q3QA 5IJSA 5L0KA 1KHNA 2XR9A 4UPLA 4LR2A 1KHLA 4MHXA 4UOOA 1O98A 4CYSA 2D1GA 1EI6A 3WAYA 3NKOA 2GSNA 3CMRA 3UN2A 4ZGAA 4KJDA 1O99A 3TG0A 1KH9A 2QZUA 1N2LA 1AUKA 4QAXA 3UO0A 4CXSA 4ZG6A 1URBA 2X98A 1FSUA 5L0BA 4ZG7A 4NWJA 3BDFA 5DLWA 3BDHA 4UPIA 3BDGB 3T01A 2IUCB 1P49A 3UN5A 3IGYB 1E1ZP 3WAWA 4CXKA 5K4PA 3IDDA 4LQYA 2W5XA 3T00A 2W8DA 3SZZA 4GTXA 2GSOA 4YR1A 1HDHA
chains in the Genus database with same CATH superfamily
1AJDA 1SHNA 2GA3A 1ALIA 1ZEDA 1KH5A 4UOPA 1URAA 4CXUA 4N7TA 4LR7A 1N2KA 3UNYA 3A52A 3M8WA 2IUCA 2IFYA 4TN0A 5KXAA 1KHJA 2W5QA 5L0EA 1AJCA 2G9YA 4NWXA 4ZG9A 2VQRA 1ALKA 2W5RA 3MK1A 1ANIA 1EW8A 3LXQA 4GTZA 3WAVA 5LIAA 4KAYA 1KHKA 5AJ9A 1ED8A 2ZKTA 4FDIA 5EGEA 1E33P 1AJAA 2XRGA 2W8SA 4KAVA 5DLVA 3NKPA 5LQQA 1HJKA 1EW9A 1ALHA 3WBHA 4LRFA 3MK2A 5TJ3A 4LR8A 1ED9A 3T02A 3NKQA 1KH7A 4B56A 1B8JA 1Y7AA 2W5SA 3NVLA 5GOVA 4CYRA 4LREA 1ELZA 2GLQA 3E2DA 2RH6A 3TX0A 2W5TA 2W5VA 3M7VA 5HRTA 3BDGA 3KD8A 3NKMA 5DLTA 3ED4A 1KH4A 1SHQA 3IGZB 4GTYA 1K7HA 4UPKA 2GSUA 1EJJA 4KM4A 1ALJA 4UPHA 4LRDA 3WAXA 5C66A 4MIVA 5LRNA 3DYCA 4MY4A 1ZEFA 4LRCA 4UORA 1EQJA 1Y6VA 3B5QA 1ELYA 3DPCA 1ZEBA 3NKRA 5GRRA 4GTWA 1AJBA 5LRMA 3OT9A 5IJQA 1ANJA 5EGHA 4LRBA 3NKNA 3M8ZA 1HQAA 4FDJA 4LR9A 4LRAA 5INHA 3TWZA 2W5WA 3M8YA 3SZYA 1EW2A 3UN3A 1E2SP 1E3CP 1ELXA 4KJGA 2ANHA 3MK0A 3Q3QA 5IJSA 5L0KA 1KHNA 2XR9A 4UPLA 4LR2A 1KHLA 4MHXA 4UOOA 1O98A 4CYSA 2D1GA 1EI6A 3WAYA 3NKOA 2GSNA 3CMRA 3UN2A 4ZGAA 4KJDA 1O99A 3TG0A 1KH9A 2QZUA 1N2LA 1AUKA 4QAXA 3UO0A 4CXSA 4ZG6A 1URBA 2X98A 1FSUA 5L0BA 4ZG7A 4NWJA 3BDFA 5DLWA 3BDHA 4UPIA 3BDGB 3T01A 2IUCB 1P49A 3UN5A 3IGYB 1E1ZP 3WAWA 4CXKA 5K4PA 3IDDA 4LQYA 2W5XA 3T00A 2W8DA 3SZZA 4GTXA 2GSOA 4YR1A 1HDHA
chains in the Genus database with same CATH topology
1AJDA 1SHNA 2GA3A 1ALIA 1ZEDA 1KH5A 4UOPA 1URAA 4CXUA 4N7TA 4LR7A 1N2KA 3UNYA 3A52A 3M8WA 2IUCA 2IFYA 4TN0A 5KXAA 1KHJA 2W5QA 5L0EA 1AJCA 2G9YA 4NWXA 4ZG9A 2VQRA 1ALKA 2W5RA 3MK1A 1ANIA 1EW8A 3LXQA 4GTZA 3WAVA 5LIAA 4KAYA 1KHKA 5AJ9A 1ED8A 2ZKTA 4FDIA 5EGEA 1E33P 1AJAA 2XRGA 2W8SA 4KAVA 5DLVA 3NKPA 5LQQA 1HJKA 1EW9A 1ALHA 3WBHA 4LRFA 3MK2A 5TJ3A 4LR8A 1ED9A 3T02A 3NKQA 1KH7A 4B56A 1B8JA 1Y7AA 2W5SA 3NVLA 5GOVA 4CYRA 4LREA 1ELZA 2GLQA 3E2DA 2RH6A 3TX0A 2W5TA 2W5VA 3M7VA 5HRTA 3BDGA 3KD8A 3NKMA 5DLTA 3ED4A 1KH4A 1SHQA 3IGZB 4GTYA 1K7HA 4UPKA 2GSUA 1EJJA 4KM4A 1ALJA 4UPHA 4LRDA 3WAXA 5C66A 4MIVA 5LRNA 3DYCA 4MY4A 1ZEFA 4LRCA 4UORA 1EQJA 1Y6VA 3B5QA 1ELYA 3DPCA 1ZEBA 3NKRA 5GRRA 4GTWA 1AJBA 5LRMA 3OT9A 5IJQA 1ANJA 5EGHA 4LRBA 3NKNA 3M8ZA 1HQAA 4FDJA 4LR9A 4LRAA 5INHA 3TWZA 2W5WA 3M8YA 3SZYA 1EW2A 3UN3A 1E2SP 1E3CP 1ELXA 4KJGA 2ANHA 3MK0A 3Q3QA 5IJSA 5L0KA 1KHNA 2XR9A 4UPLA 4LR2A 1KHLA 4MHXA 4UOOA 1O98A 4CYSA 2D1GA 1EI6A 3WAYA 3NKOA 2GSNA 3CMRA 3UN2A 4ZGAA 4KJDA 1O99A 3TG0A 1KH9A 2QZUA 1N2LA 1AUKA 4QAXA 3UO0A 4CXSA 4ZG6A 1URBA 2X98A 1FSUA 5L0BA 4ZG7A 4NWJA 3BDFA 5DLWA 3BDHA 4UPIA 3BDGB 3T01A 2IUCB 1P49A 3UN5A 3IGYB 1E1ZP 3WAWA 4CXKA 5K4PA 3IDDA 4LQYA 2W5XA 3T00A 2W8DA 3SZZA 4GTXA 2GSOA 4YR1A 1HDHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJD A;  1SHN A;  2GA3 A;  1ALI A;  1ZED A;  1KH5 A;  4UOP A;  1URA A;  4CXU A;  4N7T A;  4LR7 A;  1N2K A;  3UNY A;  3A52 A;  3M8W A;  2IUC A;  2IFY A;  4TN0 A;  5KXA A;  1KHJ A;  2W5Q A;  5L0E A;  1AJC A;  2G9Y A;  4NWX A;  4ZG9 A;  2VQR A;  1ALK A;  2W5R A;  3MK1 A;  1ANI A;  1EW8 A;  3LXQ A;  4GTZ A;  3WAV A;  5LIA A;  4KAY A;  1KHK A;  5AJ9 A;  1ED8 A;  2ZKT A;  4FDI A;  5EGE A;  1E33 P;  1AJA A;  2XRG A;  2W8S A;  4KAV A;  5DLV A;  3NKP A;  5LQQ A;  1HJK A;  1EW9 A;  1ALH A;  3WBH A;  4LRF A;  3MK2 A;  5TJ3 A;  4LR8 A;  1ED9 A;  3T02 A;  3NKQ A;  1KH7 A;  4B56 A;  1B8J A;  1Y7A A;  2W5S A;  3NVL A;  5GOV A;  4CYR A;  4LRE A;  1ELZ A;  2GLQ A;  3E2D A;  2RH6 A;  3TX0 A;  2W5T A;  2W5V A;  3M7V A;  5HRT A;  3BDG A;  3KD8 A;  3NKM A;  5DLT A;  3ED4 A;  1KH4 A;  1SHQ A;  3IGZ B;  4GTY A;  1K7H A;  4UPK A;  2GSU A;  1EJJ A;  4KM4 A;  1ALJ A;  4UPH A;  4LRD A;  3WAX A;  5C66 A;  4MIV A;  5LRN A;  3DYC A;  4MY4 A;  1ZEF A;  4LRC A;  4UOR A;  1EQJ A;  1Y6V A;  3B5Q A;  1ELY A;  3DPC A;  1ZEB A;  3NKR A;  5GRR A;  4GTW A;  1AJB A;  5LRM A;  3OT9 A;  5IJQ A;  1ANJ A;  5EGH A;  4LRB A;  3NKN A;  3M8Z A;  1HQA A;  4FDJ A;  4LR9 A;  4LRA A;  5INH A;  3TWZ A;  2W5W A;  3M8Y A;  3SZY A;  1EW2 A;  3UN3 A;  1E2S P;  1E3C P;  1ELX A;  4KJG A;  2ANH A;  3MK0 A;  3Q3Q A;  5IJS A;  5L0K A;  1KHN A;  2XR9 A;  4UPL A;  4LR2 A;  1KHL A;  4MHX A;  4UOO A;  1O98 A;  4CYS A;  2D1G A;  1EI6 A;  3WAY A;  3NKO A;  2GSN A;  3CMR A;  3UN2 A;  4ZGA A;  4KJD A;  1O99 A;  3TG0 A;  1KH9 A;  2QZU A;  1N2L A;  1AUK A;  4QAX A;  3UO0 A;  4CXS A;  4ZG6 A;  1URB A;  2X98 A;  1FSU A;  5L0B A;  4ZG7 A;  4NWJ A;  3BDF A;  5DLW A;  3BDH A;  4UPI A;  3BDG B;  3T01 A;  2IUC B;  1P49 A;  3UN5 A;  3IGY B;  1E1Z P;  3WAW A;  4CXK A;  5K4P A;  3IDD A;  4LQY A;  2W5X A;  3T00 A;  2W8D A;  3SZZ A;  4GTX A;  2GSO A;  4YR1 A;  1HDH A; 
#chains in the Genus database with same CATH topology
 1AJD A;  1SHN A;  2GA3 A;  1ALI A;  1ZED A;  1KH5 A;  4UOP A;  1URA A;  4CXU A;  4N7T A;  4LR7 A;  1N2K A;  3UNY A;  3A52 A;  3M8W A;  2IUC A;  2IFY A;  4TN0 A;  5KXA A;  1KHJ A;  2W5Q A;  5L0E A;  1AJC A;  2G9Y A;  4NWX A;  4ZG9 A;  2VQR A;  1ALK A;  2W5R A;  3MK1 A;  1ANI A;  1EW8 A;  3LXQ A;  4GTZ A;  3WAV A;  5LIA A;  4KAY A;  1KHK A;  5AJ9 A;  1ED8 A;  2ZKT A;  4FDI A;  5EGE A;  1E33 P;  1AJA A;  2XRG A;  2W8S A;  4KAV A;  5DLV A;  3NKP A;  5LQQ A;  1HJK A;  1EW9 A;  1ALH A;  3WBH A;  4LRF A;  3MK2 A;  5TJ3 A;  4LR8 A;  1ED9 A;  3T02 A;  3NKQ A;  1KH7 A;  4B56 A;  1B8J A;  1Y7A A;  2W5S A;  3NVL A;  5GOV A;  4CYR A;  4LRE A;  1ELZ A;  2GLQ A;  3E2D A;  2RH6 A;  3TX0 A;  2W5T A;  2W5V A;  3M7V A;  5HRT A;  3BDG A;  3KD8 A;  3NKM A;  5DLT A;  3ED4 A;  1KH4 A;  1SHQ A;  3IGZ B;  4GTY A;  1K7H A;  4UPK A;  2GSU A;  1EJJ A;  4KM4 A;  1ALJ A;  4UPH A;  4LRD A;  3WAX A;  5C66 A;  4MIV A;  5LRN A;  3DYC A;  4MY4 A;  1ZEF A;  4LRC A;  4UOR A;  1EQJ A;  1Y6V A;  3B5Q A;  1ELY A;  3DPC A;  1ZEB A;  3NKR A;  5GRR A;  4GTW A;  1AJB A;  5LRM A;  3OT9 A;  5IJQ A;  1ANJ A;  5EGH A;  4LRB A;  3NKN A;  3M8Z A;  1HQA A;  4FDJ A;  4LR9 A;  4LRA A;  5INH A;  3TWZ A;  2W5W A;  3M8Y A;  3SZY A;  1EW2 A;  3UN3 A;  1E2S P;  1E3C P;  1ELX A;  4KJG A;  2ANH A;  3MK0 A;  3Q3Q A;  5IJS A;  5L0K A;  1KHN A;  2XR9 A;  4UPL A;  4LR2 A;  1KHL A;  4MHX A;  4UOO A;  1O98 A;  4CYS A;  2D1G A;  1EI6 A;  3WAY A;  3NKO A;  2GSN A;  3CMR A;  3UN2 A;  4ZGA A;  4KJD A;  1O99 A;  3TG0 A;  1KH9 A;  2QZU A;  1N2L A;  1AUK A;  4QAX A;  3UO0 A;  4CXS A;  4ZG6 A;  1URB A;  2X98 A;  1FSU A;  5L0B A;  4ZG7 A;  4NWJ A;  3BDF A;  5DLW A;  3BDH A;  4UPI A;  3BDG B;  3T01 A;  2IUC B;  1P49 A;  3UN5 A;  3IGY B;  1E1Z P;  3WAW A;  4CXK A;  5K4P A;  3IDD A;  4LQY A;  2W5X A;  3T00 A;  2W8D A;  3SZZ A;  4GTX A;  2GSO A;  4YR1 A;  1HDH A; 
#chains in the Genus database with same CATH homology
 1AJD A;  1SHN A;  2GA3 A;  1ALI A;  1ZED A;  1KH5 A;  4UOP A;  1URA A;  4CXU A;  4N7T A;  4LR7 A;  1N2K A;  3UNY A;  3A52 A;  3M8W A;  2IUC A;  2IFY A;  4TN0 A;  5KXA A;  1KHJ A;  2W5Q A;  5L0E A;  1AJC A;  2G9Y A;  4NWX A;  4ZG9 A;  2VQR A;  1ALK A;  2W5R A;  3MK1 A;  1ANI A;  1EW8 A;  3LXQ A;  4GTZ A;  3WAV A;  5LIA A;  4KAY A;  1KHK A;  5AJ9 A;  1ED8 A;  2ZKT A;  4FDI A;  5EGE A;  1E33 P;  1AJA A;  2XRG A;  2W8S A;  4KAV A;  5DLV A;  3NKP A;  5LQQ A;  1HJK A;  1EW9 A;  1ALH A;  3WBH A;  4LRF A;  3MK2 A;  5TJ3 A;  4LR8 A;  1ED9 A;  3T02 A;  3NKQ A;  1KH7 A;  4B56 A;  1B8J A;  1Y7A A;  2W5S A;  3NVL A;  5GOV A;  4CYR A;  4LRE A;  1ELZ A;  2GLQ A;  3E2D A;  2RH6 A;  3TX0 A;  2W5T A;  2W5V A;  3M7V A;  5HRT A;  3BDG A;  3KD8 A;  3NKM A;  5DLT A;  3ED4 A;  1KH4 A;  1SHQ A;  3IGZ B;  4GTY A;  1K7H A;  4UPK A;  2GSU A;  1EJJ A;  4KM4 A;  1ALJ A;  4UPH A;  4LRD A;  3WAX A;  5C66 A;  4MIV A;  5LRN A;  3DYC A;  4MY4 A;  1ZEF A;  4LRC A;  4UOR A;  1EQJ A;  1Y6V A;  3B5Q A;  1ELY A;  3DPC A;  1ZEB A;  3NKR A;  5GRR A;  4GTW A;  1AJB A;  5LRM A;  3OT9 A;  5IJQ A;  1ANJ A;  5EGH A;  4LRB A;  3NKN A;  3M8Z A;  1HQA A;  4FDJ A;  4LR9 A;  4LRA A;  5INH A;  3TWZ A;  2W5W A;  3M8Y A;  3SZY A;  1EW2 A;  3UN3 A;  1E2S P;  1E3C P;  1ELX A;  4KJG A;  2ANH A;  3MK0 A;  3Q3Q A;  5IJS A;  5L0K A;  1KHN A;  2XR9 A;  4UPL A;  4LR2 A;  1KHL A;  4MHX A;  4UOO A;  1O98 A;  4CYS A;  2D1G A;  1EI6 A;  3WAY A;  3NKO A;  2GSN A;  3CMR A;  3UN2 A;  4ZGA A;  4KJD A;  1O99 A;  3TG0 A;  1KH9 A;  2QZU A;  1N2L A;  1AUK A;  4QAX A;  3UO0 A;  4CXS A;  4ZG6 A;  1URB A;  2X98 A;  1FSU A;  5L0B A;  4ZG7 A;  4NWJ A;  3BDF A;  5DLW A;  3BDH A;  4UPI A;  3BDG B;  3T01 A;  2IUC B;  1P49 A;  3UN5 A;  3IGY B;  1E1Z P;  3WAW A;  4CXK A;  5K4P A;  3IDD A;  4LQY A;  2W5X A;  3T00 A;  2W8D A;  3SZZ A;  4GTX A;  2GSO A;  4YR1 A;  1HDH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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