3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CG8862
publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
source organism Drosophila melanogaster
molecule tags Hydrolase inhibitor/hydrolase
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
2XRGA 4GTXA 4E3YA 5GKPA 2XH3A 5IJQA 4A1NA 3WAVA 1SMNA 5KXAA 3NKPA 5L0EA 4ZGAA 2XGRA 5DLWA 5LQQA 5HRTA 5L0KA 3NKNA 1QL0A 5DLTA 4ZG6A 3OWVA 4GTZA 4GTYA 3WAYA 3WAXA 5IJSA 2O3BA 4QN0A 4QGOA 4ZG9A 5GKCA 3NKRA 3NKQA 2XR9A 1G8TA 1ZM8A 5DLVA 5INHA 3WAWA 3NKOA 4QH0A 4GTWA 3ISMA 5L0BA 3NKMA 1QAEA 5LIAA 3S5BA 4B56A 4ZG7A
chains in the Genus database with same CATH superfamily
2XRGA 4GTXA 4E3YA 5GKPA 2XH3A 5IJQA 4A1NA 3WAVA 1SMNA 5KXAA 3NKPA 5L0EA 4ZGAA 2XGRA 5DLWA 5LQQA 5HRTA 5L0KA 3NKNA 1QL0A 5DLTA 4ZG6A 3OWVA 4GTZA 4GTYA 3WAYA 3WAXA 5IJSA 2O3BA 4QN0A 4QGOA 4ZG9A 5GKCA 3NKRA 3NKQA 2XR9A 1G8TA 1ZM8A 5DLVA 5INHA 3WAWA 3NKOA 4QH0A 4GTWA 3ISMA 5L0BA 3NKMA 1QAEA 5LIAA 3S5BA 4B56A 4ZG7A
chains in the Genus database with same CATH topology
2XRGA 4GTXA 4E3YA 5GKPA 2XH3A 5IJQA 4A1NA 3WAVA 1SMNA 5KXAA 3NKPA 5L0EA 4ZGAA 2XGRA 5DLWA 5LQQA 5HRTA 5L0KA 3NKNA 1QL0A 5DLTA 4ZG6A 3OWVA 4GTZA 4GTYA 3WAYA 3WAXA 5IJSA 2O3BA 4QN0A 4QGOA 4ZG9A 5GKCA 3NKRA 3NKQA 2XR9A 1G8TA 1ZM8A 5DLVA 5INHA 3WAWA 3NKOA 4QH0A 4GTWA 3ISMA 5L0BA 3NKMA 1QAEA 5LIAA 3S5BA 4B56A 4ZG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XRG A;  4GTX A;  4E3Y A;  5GKP A;  2XH3 A;  5IJQ A;  4A1N A;  3WAV A;  1SMN A;  5KXA A;  3NKP A;  5L0E A;  4ZGA A;  2XGR A;  5DLW A;  5LQQ A;  5HRT A;  5L0K A;  3NKN A;  1QL0 A;  5DLT A;  4ZG6 A;  3OWV A;  4GTZ A;  4GTY A;  3WAY A;  3WAX A;  5IJS A;  2O3B A;  4QN0 A;  4QGO A;  4ZG9 A;  5GKC A;  3NKR A;  3NKQ A;  2XR9 A;  1G8T A;  1ZM8 A;  5DLV A;  5INH A;  3WAW A;  3NKO A;  4QH0 A;  4GTW A;  3ISM A;  5L0B A;  3NKM A;  1QAE A;  5LIA A;  3S5B A;  4B56 A;  4ZG7 A; 
#chains in the Genus database with same CATH topology
 2XRG A;  4GTX A;  4E3Y A;  5GKP A;  2XH3 A;  5IJQ A;  4A1N A;  3WAV A;  1SMN A;  5KXA A;  3NKP A;  5L0E A;  4ZGA A;  2XGR A;  5DLW A;  5LQQ A;  5HRT A;  5L0K A;  3NKN A;  1QL0 A;  5DLT A;  4ZG6 A;  3OWV A;  4GTZ A;  4GTY A;  3WAY A;  3WAX A;  5IJS A;  2O3B A;  4QN0 A;  4QGO A;  4ZG9 A;  5GKC A;  3NKR A;  3NKQ A;  2XR9 A;  1G8T A;  1ZM8 A;  5DLV A;  5INH A;  3WAW A;  3NKO A;  4QH0 A;  4GTW A;  3ISM A;  5L0B A;  3NKM A;  1QAE A;  5LIA A;  3S5B A;  4B56 A;  4ZG7 A; 
#chains in the Genus database with same CATH homology
 2XRG A;  4GTX A;  4E3Y A;  5GKP A;  2XH3 A;  5IJQ A;  4A1N A;  3WAV A;  1SMN A;  5KXA A;  3NKP A;  5L0E A;  4ZGA A;  2XGR A;  5DLW A;  5LQQ A;  5HRT A;  5L0K A;  3NKN A;  1QL0 A;  5DLT A;  4ZG6 A;  3OWV A;  4GTZ A;  4GTY A;  3WAY A;  3WAX A;  5IJS A;  2O3B A;  4QN0 A;  4QGO A;  4ZG9 A;  5GKC A;  3NKR A;  3NKQ A;  2XR9 A;  1G8T A;  1ZM8 A;  5DLV A;  5INH A;  3WAW A;  3NKO A;  4QH0 A;  4GTW A;  3ISM A;  5L0B A;  3NKM A;  1QAE A;  5LIA A;  3S5B A;  4B56 A;  4ZG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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