3ISMA

Crystal structure of the endog/endogi complex: mechanism of endog inhibition
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
245
structure length
245
Chain Sequence
TATPSRIGQIMKYGFPGLDHVRSHSDYVLSYDRRNRVPHWVFEHLTAESVAKNDAVDRSKCDFKQDESIHPFFRSQNTDYRRSGYDRGHMAAAGNHRLHQKHCDETFYLSNMAPQVGQGFNRDAWNTLEAHVRRLTKTYSNVYVCTGPLYLPHKEDDGKSYVKYEVIGANTVAVPTHFYKVIVGESADHKLHMESYVMPNQVISNDTPISVFQVPPESVERSAGLLFFDQINRKQLTTINGKKVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
pubmed doi rcsb
source organism Drosophila melanogaster
molecule tags Hydrolase inhibitor/hydrolase
molecule keywords CG8862
total genus 71
structure length 245
sequence length 245
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3ismA00
5LQQA 3S5BA 5IJSA 5HRTA 3NKPA 4E3YA 3OWVA 3ISMA 5GKPA 2O3BA 3WAVA 3WAXA 3NKMA 2XRGA 3NKRA 4ZG9A 5L0KA 5DLWA 5LIAA 5L0BA 4ZG7A 3WAWA 1QL0A 5DLVA 1G8TA 5GKCA 3NKNA 3NKQA 4QH0A 5DLTA 4B56A 4QGOA 4GTXA 3WAYA 1ZM8A 4GTWA 4GTZA 5L0EA 5IJQA 2XH3A 5KXAA 3NKOA 1QAEA 2XR9A 4QN0A 2XGRA 4ZG6A 5INHA 4A1NA 1SMNA 4ZGAA 4GTYA
chains in the Genus database with same CATH superfamily
5LQQA 3S5BA 5IJSA 5HRTA 3NKPA 4E3YA 3OWVA 3ISMA 5GKPA 2O3BA 3WAVA 3WAXA 3NKMA 2XRGA 3NKRA 4ZG9A 5L0KA 5DLWA 5LIAA 5L0BA 4ZG7A 3WAWA 1QL0A 5DLVA 1G8TA 5GKCA 3NKNA 3NKQA 4QH0A 5DLTA 4B56A 4QGOA 4GTXA 3WAYA 1ZM8A 4GTWA 4GTZA 5L0EA 5IJQA 2XH3A 5KXAA 3NKOA 1QAEA 2XR9A 4QN0A 2XGRA 4ZG6A 5INHA 4A1NA 1SMNA 4ZGAA 4GTYA
chains in the Genus database with same CATH topology
5LQQA 3S5BA 5IJSA 5HRTA 3NKPA 4E3YA 3OWVA 3ISMA 5GKPA 2O3BA 3WAVA 3WAXA 3NKMA 2XRGA 3NKRA 4ZG9A 5L0KA 5DLWA 5LIAA 5L0BA 4ZG7A 3WAWA 1QL0A 5DLVA 1G8TA 5GKCA 3NKNA 3NKQA 4QH0A 5DLTA 4B56A 4QGOA 4GTXA 3WAYA 1ZM8A 4GTWA 4GTZA 5L0EA 5IJQA 2XH3A 5KXAA 3NKOA 1QAEA 2XR9A 4QN0A 2XGRA 4ZG6A 5INHA 4A1NA 1SMNA 4ZGAA 4GTYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LQQ A;  3S5B A;  5IJS A;  5HRT A;  3NKP A;  4E3Y A;  3OWV A;  3ISM A;  5GKP A;  2O3B A;  3WAV A;  3WAX A;  3NKM A;  2XRG A;  3NKR A;  4ZG9 A;  5L0K A;  5DLW A;  5LIA A;  5L0B A;  4ZG7 A;  3WAW A;  1QL0 A;  5DLV A;  1G8T A;  5GKC A;  3NKN A;  3NKQ A;  4QH0 A;  5DLT A;  4B56 A;  4QGO A;  4GTX A;  3WAY A;  1ZM8 A;  4GTW A;  4GTZ A;  5L0E A;  5IJQ A;  2XH3 A;  5KXA A;  3NKO A;  1QAE A;  2XR9 A;  4QN0 A;  2XGR A;  4ZG6 A;  5INH A;  4A1N A;  1SMN A;  4ZGA A;  4GTY A; 
#chains in the Genus database with same CATH topology
 5LQQ A;  3S5B A;  5IJS A;  5HRT A;  3NKP A;  4E3Y A;  3OWV A;  3ISM A;  5GKP A;  2O3B A;  3WAV A;  3WAX A;  3NKM A;  2XRG A;  3NKR A;  4ZG9 A;  5L0K A;  5DLW A;  5LIA A;  5L0B A;  4ZG7 A;  3WAW A;  1QL0 A;  5DLV A;  1G8T A;  5GKC A;  3NKN A;  3NKQ A;  4QH0 A;  5DLT A;  4B56 A;  4QGO A;  4GTX A;  3WAY A;  1ZM8 A;  4GTW A;  4GTZ A;  5L0E A;  5IJQ A;  2XH3 A;  5KXA A;  3NKO A;  1QAE A;  2XR9 A;  4QN0 A;  2XGR A;  4ZG6 A;  5INH A;  4A1N A;  1SMN A;  4ZGA A;  4GTY A; 
#chains in the Genus database with same CATH homology
 5LQQ A;  3S5B A;  5IJS A;  5HRT A;  3NKP A;  4E3Y A;  3OWV A;  3ISM A;  5GKP A;  2O3B A;  3WAV A;  3WAX A;  3NKM A;  2XRG A;  3NKR A;  4ZG9 A;  5L0K A;  5DLW A;  5LIA A;  5L0B A;  4ZG7 A;  3WAW A;  1QL0 A;  5DLV A;  1G8T A;  5GKC A;  3NKN A;  3NKQ A;  4QH0 A;  5DLT A;  4B56 A;  4QGO A;  4GTX A;  3WAY A;  1ZM8 A;  4GTW A;  4GTZ A;  5L0E A;  5IJQ A;  2XH3 A;  5KXA A;  3NKO A;  1QAE A;  2XR9 A;  4QN0 A;  2XGR A;  4ZG6 A;  5INH A;  4A1N A;  1SMN A;  4ZGA A;  4GTY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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