3IT5A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Protease lasA
publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
total genus 46
structure length 182
sequence length 182
chains with identical sequence B, E, G
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it5A00
1GGRA 2F3GA 3IT5A 4QP5A 5B0HA 1GLEF 1GLCF 3IT7A 4LXCA 2B13A 1GLBF 1F3GA 2MP0B 3NYYA 4RNYA 2GPRA 1GLDF 1QWYA 3TUFB 5KVPA 1GLAF 1AX3A 3UZ0B 4QPBA 4ZYBA 3OURB 2GU1A 4RNZA 2B0PA 1GPRA 3CSQA 4JBWM 2HSIA 1O2FA 4BH5A 3SLUA 2B44A 1F3ZA
chains in the Genus database with same CATH superfamily
1GGRA 2F3GA 3IT5A 4QP5A 5B0HA 1GLEF 1GLCF 3IT7A 4LXCA 2B13A 1GLBF 1F3GA 2MP0B 3NYYA 4RNYA 2GPRA 1GLDF 1QWYA 3TUFB 5KVPA 1GLAF 1AX3A 3UZ0B 4QPBA 4ZYBA 3OURB 2GU1A 4RNZA 2B0PA 1GPRA 3CSQA 4JBWM 2HSIA 1O2FA 4BH5A 3SLUA 2B44A 1F3ZA
chains in the Genus database with same CATH topology
1GGRA 2F3GA 3IT5A 4QP5A 5B0HA 1GLEF 1GLCF 3IT7A 4LXCA 2B13A 1GLBF 1F3GA 2MP0B 3NYYA 4RNYA 2GPRA 1GLDF 1QWYA 3TUFB 5KVPA 1GLAF 1AX3A 3UZ0B 4QPBA 4ZYBA 3OURB 2GU1A 4RNZA 2B0PA 1GPRA 3CSQA 4JBWM 2HSIA 1O2FA 4BH5A 3SLUA 2B44A 1F3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GGR A;  2F3G A;  3IT5 A;  4QP5 A;  5B0H A;  1GLE F;  1GLC F;  3IT7 A;  4LXC A;  2B13 A;  1GLB F;  1F3G A;  2MP0 B;  3NYY A;  4RNY A;  2GPR A;  1GLD F;  1QWY A;  3TUF B;  5KVP A;  1GLA F;  1AX3 A;  3UZ0 B;  4QPB A;  4ZYB A;  3OUR B;  2GU1 A;  4RNZ A;  2B0P A;  1GPR A;  3CSQ A;  4JBW M;  2HSI A;  1O2F A;  4BH5 A;  3SLU A;  2B44 A;  1F3Z A; 
#chains in the Genus database with same CATH topology
 1GGR A;  2F3G A;  3IT5 A;  4QP5 A;  5B0H A;  1GLE F;  1GLC F;  3IT7 A;  4LXC A;  2B13 A;  1GLB F;  1F3G A;  2MP0 B;  3NYY A;  4RNY A;  2GPR A;  1GLD F;  1QWY A;  3TUF B;  5KVP A;  1GLA F;  1AX3 A;  3UZ0 B;  4QPB A;  4ZYB A;  3OUR B;  2GU1 A;  4RNZ A;  2B0P A;  1GPR A;  3CSQ A;  4JBW M;  2HSI A;  1O2F A;  4BH5 A;  3SLU A;  2B44 A;  1F3Z A; 
#chains in the Genus database with same CATH homology
 1GGR A;  2F3G A;  3IT5 A;  4QP5 A;  5B0H A;  1GLE F;  1GLC F;  3IT7 A;  4LXC A;  2B13 A;  1GLB F;  1F3G A;  2MP0 B;  3NYY A;  4RNY A;  2GPR A;  1GLD F;  1QWY A;  3TUF B;  5KVP A;  1GLA F;  1AX3 A;  3UZ0 B;  4QPB A;  4ZYB A;  3OUR B;  2GU1 A;  4RNZ A;  2B0P A;  1GPR A;  3CSQ A;  4JBW M;  2HSI A;  1O2F A;  4BH5 A;  3SLU A;  2B44 A;  1F3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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