3IUGA

Crystal structure of the rhogap domain of rics
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
203
structure length
184
Chain Sequence
GERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSQSVVVEFILNHVDVLFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Splicing
molecule keywords Rho/Cdc42/Rac GTPase-activating protein RICS
publication title Crystal structure of the RhoGAP domain of RICS
rcsb
source organism Homo sapiens
total genus 66
structure length 184
sequence length 203
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 3iugA00
1AM4A 2QV2A 1PBWA 3W6RA 3BYIA 3KUQA 1XA6A 3IUGA 5JCPA 1OW3A 5IRCA 5C5SA 1TX4A 3WPSA 3EAPA 2XS6A 3CXLA 5HPYA 5JD0A 2OVJA 2OSAA 2NGRB 3QISA 2EE4A 2MBGA 3FK2A 3MSXB 2EE5A 1F7CA 1RGPA 5C2JA 1GRNB 3WPQA
chains in the Genus database with same CATH superfamily
1AM4A 2QV2A 1PBWA 3W6RA 3BYIA 3KUQA 1XA6A 3IUGA 5JCPA 1OW3A 5IRCA 5C5SA 1TX4A 3WPSA 3EAPA 2XS6A 3CXLA 5HPYA 5JD0A 2OVJA 2OSAA 2NGRB 3QISA 2EE4A 2MBGA 3FK2A 3MSXB 2EE5A 1F7CA 1RGPA 5C2JA 1GRNB 3WPQA
chains in the Genus database with same CATH topology
1AM4A 2QV2A 1PBWA 3W6RA 3BYIA 3KUQA 1XA6A 3IUGA 5JCPA 1OW3A 5IRCA 5C5SA 1TX4A 3WPSA 3EAPA 2XS6A 3CXLA 5HPYA 5JD0A 2OVJA 2OSAA 2NGRB 3QISA 2EE4A 2MBGA 3FK2A 3MSXB 2EE5A 1F7CA 1RGPA 5C2JA 1GRNB 3WPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AM4 A;  2QV2 A;  1PBW A;  3W6R A;  3BYI A;  3KUQ A;  1XA6 A;  3IUG A;  5JCP A;  1OW3 A;  5IRC A;  5C5S A;  1TX4 A;  3WPS A;  3EAP A;  2XS6 A;  3CXL A;  5HPY A;  5JD0 A;  2OVJ A;  2OSA A;  2NGR B;  3QIS A;  2EE4 A;  2MBG A;  3FK2 A;  3MSX B;  2EE5 A;  1F7C A;  1RGP A;  5C2J A;  1GRN B;  3WPQ A; 
#chains in the Genus database with same CATH topology
 1AM4 A;  2QV2 A;  1PBW A;  3W6R A;  3BYI A;  3KUQ A;  1XA6 A;  3IUG A;  5JCP A;  1OW3 A;  5IRC A;  5C5S A;  1TX4 A;  3WPS A;  3EAP A;  2XS6 A;  3CXL A;  5HPY A;  5JD0 A;  2OVJ A;  2OSA A;  2NGR B;  3QIS A;  2EE4 A;  2MBG A;  3FK2 A;  3MSX B;  2EE5 A;  1F7C A;  1RGP A;  5C2J A;  1GRN B;  3WPQ A; 
#chains in the Genus database with same CATH homology
 1AM4 A;  2QV2 A;  1PBW A;  3W6R A;  3BYI A;  3KUQ A;  1XA6 A;  3IUG A;  5JCP A;  1OW3 A;  5IRC A;  5C5S A;  1TX4 A;  3WPS A;  3EAP A;  2XS6 A;  3CXL A;  5HPY A;  5JD0 A;  2OVJ A;  2OSA A;  2NGR B;  3QIS A;  2EE4 A;  2MBG A;  3FK2 A;  3MSX B;  2EE5 A;  1F7C A;  1RGP A;  5C2J A;  1GRN B;  3WPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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