3J7AD

Cryo-em structure of the plasmodium falciparum 80s ribosome bound to the anti-protozoan drug emetine, small subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
209
structure length
157
Chain Sequence
PISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRIRELTSLVQKRFFLCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQRAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTSILPDNISVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
pubmed doi rcsb
molecule tags Ribosome/inhibitor
molecule keywords 18S ribosomal RNA
total genus 36
structure length 157
sequence length 209
ec nomenclature
pdb deposition date 2014-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00189 Ribosomal_S3_C Ribosomal protein S3, C-terminal domain
D PF07650 KH_2 KH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1140.32 Alpha Beta 2-Layer Sandwich Ribosomal protein S3 C-terminal domain Ribosomal protein S3, C-terminal domain 3j7aD01
3J81D 4DR1C 5LMNC 4LFAC 4DV1C 2UXCC 4DR2C 4DV3C 3T1YC 3J80D 5FLXD 4NXMC 4LF8C 1XNQC 5BR8C 1IBLC 1HR0C 2ZM6C 4X62C 1IBMC 4BSZA 4GKJC 4DR3C 4X64C 4LFBC 4NXNC 4DV0C 1HNXC 1J5EC 3OTOC 1XMQC 4LF9C 4LF5C 4DR6C 4DR5C 4AQYC 5IT9D 3T1HC 2F4VC 1N34C 4OX9C 4JV5C 5A2QD 4DR4C 1N32C 3J7AD 4B3TC 2VQFC 4JI8C 2UUCC 4DV5C 2UUAC 3JAMD 1FJGC 4YHHC 4DUZC 4JI3C 5LMUC 4DV4C 4JI2C 4DR7C 1I94C 4KHPC 2HHHC 1HNZC 1XMOC 2UUBC 4GKKC 1N36C 4JI4C 2E5LC 2UU9C 4LF7C 2UXDC 4DV6C 4LF6C 4JYAC 1HNWC 4B3SC 4B3RC 4JI5C 4K0KC 4JI0C 4DV7C 1N33C 4X65C 4JI6C 4LFCC 4X66C 2UXBC 1IBKC 4LF4C 4JI7C 5IWAC 4YY3C 1XNRC 4B3MC 2VQEC 4JI1C 4DUYC 4DV2C
chains in the Genus database with same CATH superfamily
3J81D 4DR1C 5LMNC 4LFAC 4DV1C 2UXCC 4DR2C 4DV3C 3T1YC 3J80D 5FLXD 4NXMC 4LF8C 1XNQC 5BR8C 1IBLC 1HR0C 2ZM6C 4X62C 1IBMC 4BSZA 4GKJC 4DR3C 4X64C 4LFBC 4NXNC 4DV0C 1HNXC 1J5EC 3OTOC 1XMQC 4LF9C 4LF5C 4DR6C 4DR5C 4AQYC 5IT9D 3T1HC 2F4VC 1N34C 4OX9C 4JV5C 5A2QD 4DR4C 1XDXA 1N32C 3J7AD 4B3TC 2VQFC 4JI8C 2UUCC 4DV5C 2UUAC 3JAMD 1FJGC 4YHHC 4DUZC 4JI3C 5LMUC 4DV4C 4JI2C 4DR7C 1I94C 4KHPC 2HHHC 1HNZC 1XMOC 2UUBC 4GKKC 1N36C 4JI4C 2E5LC 2UU9C 4LF7C 2UXDC 3FM7A 4DV6C 4LF6C 4JYAC 1HNWC 4B3SC 4B3RC 4JI5C 4K0KC 4JI0C 4DV7C 2PG1E 1N33C 4X65C 2ZTBA 4JI6C 4LFCC 4X66C 2UXBC 1IBKC 1YGTA 4LF4C 4JI7C 5IWAC 4YY3C 1XNRC 4B3MC 2VQEC 4JI1C 4DUYC 4DV2C
chains in the Genus database with same CATH topology
3J81D 4DR1C 5LMNC 4LFAC 4DV1C 2UXCC 4DR2C 4DV3C 3T1YC 3J80D 5FLXD 4NXMC 4LF8C 1XNQC 5BR8C 1IBLC 1HR0C 2ZM6C 4X62C 1IBMC 4BSZA 4GKJC 4DR3C 4X64C 4LFBC 4NXNC 4DV0C 1HNXC 1J5EC 3OTOC 1XMQC 4LF9C 4LF5C 4DR6C 4DR5C 4AQYC 5IT9D 3T1HC 2F4VC 1N34C 4OX9C 4JV5C 5A2QD 4DR4C 1N32C 3J7AD 4B3TC 2VQFC 4JI8C 2UUCC 4DV5C 2UUAC 3JAMD 1FJGC 4YHHC 4DUZC 4JI3C 5LMUC 4DV4C 4JI2C 4DR7C 1I94C 4KHPC 2HHHC 1HNZC 1XMOC 2UUBC 4GKKC 1N36C 4JI4C 2E5LC 2UU9C 4LF7C 2UXDC 4DV6C 4LF6C 4JYAC 1HNWC 4B3SC 4B3RC 4JI5C 4K0KC 4JI0C 4DV7C 1N33C 4X65C 4JI6C 4LFCC 4X66C 2UXBC 1IBKC 4LF4C 4JI7C 5IWAC 4YY3C 1XNRC 4B3MC 2VQEC 4JI1C 4DUYC 4DV2C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3J81 D;  4DR1 C;  5LMN C;  4LFA C;  4DV1 C;  2UXC C;  4DR2 C;  4DV3 C;  3T1Y C;  3J80 D;  5FLX D;  4NXM C;  4LF8 C;  1XNQ C;  5BR8 C;  1IBL C;  1HR0 C;  2ZM6 C;  4X62 C;  1IBM C;  4BSZ A;  4GKJ C;  4DR3 C;  4X64 C;  4LFB C;  4NXN C;  4DV0 C;  1HNX C;  1J5E C;  3OTO C;  1XMQ C;  4LF9 C;  4LF5 C;  4DR6 C;  4DR5 C;  4AQY C;  5IT9 D;  3T1H C;  2F4V C;  1N34 C;  4OX9 C;  4JV5 C;  5A2Q D;  4DR4 C;  1N32 C;  3J7A D;  4B3T C;  2VQF C;  4JI8 C;  2UUC C;  4DV5 C;  2UUA C;  3JAM D;  1FJG C;  4YHH C;  4DUZ C;  4JI3 C;  5LMU C;  4DV4 C;  4JI2 C;  4DR7 C;  1I94 C;  4KHP C;  2HHH C;  1HNZ C;  1XMO C;  2UUB C;  4GKK C;  1N36 C;  4JI4 C;  2E5L C;  2UU9 C;  4LF7 C;  2UXD C;  4DV6 C;  4LF6 C;  4JYA C;  1HNW C;  4B3S C;  4B3R C;  4JI5 C;  4K0K C;  4JI0 C;  4DV7 C;  1N33 C;  4X65 C;  4JI6 C;  4LFC C;  4X66 C;  2UXB C;  1IBK C;  4LF4 C;  4JI7 C;  5IWA C;  4YY3 C;  1XNR C;  4B3M C;  2VQE C;  4JI1 C;  4DUY C;  4DV2 C; 
#chains in the Genus database with same CATH topology
 3J81 D;  4DR1 C;  5LMN C;  4LFA C;  4DV1 C;  2UXC C;  4DR2 C;  4DV3 C;  3T1Y C;  3J80 D;  5FLX D;  4NXM C;  4LF8 C;  1XNQ C;  5BR8 C;  1IBL C;  1HR0 C;  2ZM6 C;  4X62 C;  1IBM C;  4BSZ A;  4GKJ C;  4DR3 C;  4X64 C;  4LFB C;  4NXN C;  4DV0 C;  1HNX C;  1J5E C;  3OTO C;  1XMQ C;  4LF9 C;  4LF5 C;  4DR6 C;  4DR5 C;  4AQY C;  5IT9 D;  3T1H C;  2F4V C;  1N34 C;  4OX9 C;  4JV5 C;  5A2Q D;  4DR4 C;  1XDX A;  1N32 C;  3J7A D;  4B3T C;  2VQF C;  4JI8 C;  2UUC C;  4DV5 C;  2UUA C;  3JAM D;  1FJG C;  4YHH C;  4DUZ C;  4JI3 C;  5LMU C;  4DV4 C;  4JI2 C;  4DR7 C;  1I94 C;  4KHP C;  2HHH C;  1HNZ C;  1XMO C;  2UUB C;  4GKK C;  1N36 C;  4JI4 C;  2E5L C;  2UU9 C;  4LF7 C;  2UXD C;  3FM7 A;  4DV6 C;  4LF6 C;  4JYA C;  1HNW C;  4B3S C;  4B3R C;  4JI5 C;  4K0K C;  4JI0 C;  4DV7 C;  2PG1 E;  1N33 C;  4X65 C;  2ZTB A;  4JI6 C;  4LFC C;  4X66 C;  2UXB C;  1IBK C;  1YGT A;  4LF4 C;  4JI7 C;  5IWA C;  4YY3 C;  1XNR C;  4B3M C;  2VQE C;  4JI1 C;  4DUY C;  4DV2 C; 
#chains in the Genus database with same CATH homology
 3J81 D;  4DR1 C;  5LMN C;  4LFA C;  4DV1 C;  2UXC C;  4DR2 C;  4DV3 C;  3T1Y C;  3J80 D;  5FLX D;  4NXM C;  4LF8 C;  1XNQ C;  5BR8 C;  1IBL C;  1HR0 C;  2ZM6 C;  4X62 C;  1IBM C;  4BSZ A;  4GKJ C;  4DR3 C;  4X64 C;  4LFB C;  4NXN C;  4DV0 C;  1HNX C;  1J5E C;  3OTO C;  1XMQ C;  4LF9 C;  4LF5 C;  4DR6 C;  4DR5 C;  4AQY C;  5IT9 D;  3T1H C;  2F4V C;  1N34 C;  4OX9 C;  4JV5 C;  5A2Q D;  4DR4 C;  1N32 C;  3J7A D;  4B3T C;  2VQF C;  4JI8 C;  2UUC C;  4DV5 C;  2UUA C;  3JAM D;  1FJG C;  4YHH C;  4DUZ C;  4JI3 C;  5LMU C;  4DV4 C;  4JI2 C;  4DR7 C;  1I94 C;  4KHP C;  2HHH C;  1HNZ C;  1XMO C;  2UUB C;  4GKK C;  1N36 C;  4JI4 C;  2E5L C;  2UU9 C;  4LF7 C;  2UXD C;  4DV6 C;  4LF6 C;  4JYA C;  1HNW C;  4B3S C;  4B3R C;  4JI5 C;  4K0K C;  4JI0 C;  4DV7 C;  1N33 C;  4X65 C;  4JI6 C;  4LFC C;  4X66 C;  2UXB C;  1IBK C;  4LF4 C;  4JI7 C;  5IWA C;  4YY3 C;  1XNR C;  4B3M C;  2VQE C;  4JI1 C;  4DUY C;  4DV2 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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