3JARM

Cryo-em structure of gdp-microtubule co-polymerized with eb3
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
131
structure length
131
Chain Sequence
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Tubulin alpha-1B chain
total genus 33
structure length 131
sequence length 131
chains with identical sequence N
ec nomenclature
pdb deposition date 2015-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3jarM00
1AA2A 3JARM 2YRNA 1PXYA 1TJTA 2D89A 3JALM 2E9KA 2WA7A 4EDMA 2D87A 2DK9A 3KY9A 2VZGB 4Q58A 1WIXA 3KMWB 2EE7A 1VKAA 2RR8A 1WYNA 1WYLA 2D86A 1PA7A 3CO1A 5A38A 1H67A 1BHDA 2WA6A 2D88A 1RT8A 1WJOA 2VZCA 5L0OA 2VZIB 2EYIA 1SH6A 3REPB 2QJXA 3KMUB 3HORA 1WYMA 1DXXA 1UJOA 2K3SA 2L3GA 2EYNA 2JV9A 3HOPA 3JAKM 4Q57B 3I6XA 1P2XA 1WYRA 1V5KA 4Q59A 2VZDA 5J8EA 2D85A 2R0OA 2R8UA 4B7LA 3F7PA 2WA5A 5A36A 2K2RA 5BVRA 3FERA 1AOAA 1MB8A 2QJZA 1UEGA 3HOCA 1SH5A 4EDLA 4EDNA 1P5SA 1BKRA 5A4BA 4TXKA 1WYOA 2WFNA 1QAGA 1WKUA 4TXIA 1WYQA 5A37A 1WYPA
chains in the Genus database with same CATH superfamily
1AA2A 2EQOA 3JARM 2YRNA 1PXYA 1EUVA 1TJTA 2D89A 3JALM 2E9KA 2WA7A 4EDMA 4LVPA 2D87A 2HKPA 2DK9A 3KY9A 2VZGB 4Q58A 1WIXA 4DDPA 3KMWB 2EE7A 1VKAA 2RR8A 1WYNA 1WYLA 2D86A 1PA7A 3CO1A 5A38A 3VP7A 1H67A 1BHDA 2WA6A 2D88A 2WDTA 1RT8A 1WJOA 2VZCA 5L0OA 2VZIB 2EYIA 1SH6A 2HL9A 3REPB 5FMTA 2QJXA 3KMUB 3HORA 1WYMA 1DXXA 1UJOA 2K3SA 2L3GA 2EYNA 2JV9A 3HOPA 2WE6A 3JAKM 4Q57B 3I6XA 1P2XA 1WYRA 1V5KA 4Q59A 2VZDA 2VE7C 5J8EA 3EAYA 2D85A 2R0OA 2R8UA 4B7LA 3F7PA 2WA5A 5A36A 2K2RA 5BVRA 3FERA 1AOAA 1MB8A 2QJZA 1UEGA 3HOCA 1SH5A 4EDLA 4EDNA 1P5SA 1BKRA 5A4BA 4LVRA 4TXKA 1WYOA 2VE7A 1QAGA 1WKUA 2WFNA 4TXIA 1WYQA 2IGPA 5A37A 2HL8A 1WYPA 5FMUA
chains in the Genus database with same CATH topology
1AA2A 3JARM 2YRNA 1PXYA 1TJTA 2D89A 3JALM 2E9KA 2WA7A 4EDMA 2D87A 2DK9A 3KY9A 2VZGB 4Q58A 1WIXA 3KMWB 2EE7A 1VKAA 2RR8A 1WYNA 1WYLA 2D86A 1PA7A 3CO1A 5A38A 1H67A 1BHDA 2WA6A 2D88A 1RT8A 1WJOA 2VZCA 5L0OA 2VZIB 2EYIA 1SH6A 3REPB 2QJXA 3KMUB 3HORA 1WYMA 1DXXA 1UJOA 2K3SA 2L3GA 2EYNA 2JV9A 3HOPA 3JAKM 4Q57B 3I6XA 1P2XA 1WYRA 1V5KA 4Q59A 2VZDA 5J8EA 2D85A 2R0OA 2R8UA 4B7LA 3F7PA 2WA5A 5A36A 2K2RA 5BVRA 3FERA 1AOAA 1MB8A 2QJZA 1UEGA 3HOCA 1SH5A 4EDLA 4EDNA 1P5SA 1BKRA 5A4BA 4TXKA 1WYOA 2WFNA 1QAGA 1WKUA 4TXIA 1WYQA 5A37A 1WYPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AA2 A;  3JAR M;  2YRN A;  1PXY A;  1TJT A;  2D89 A;  3JAL M;  2E9K A;  2WA7 A;  4EDM A;  2D87 A;  2DK9 A;  3KY9 A;  2VZG B;  4Q58 A;  1WIX A;  3KMW B;  2EE7 A;  1VKA A;  2RR8 A;  1WYN A;  1WYL A;  2D86 A;  1PA7 A;  3CO1 A;  5A38 A;  1H67 A;  1BHD A;  2WA6 A;  2D88 A;  1RT8 A;  1WJO A;  2VZC A;  5L0O A;  2VZI B;  2EYI A;  1SH6 A;  3REP B;  2QJX A;  3KMU B;  3HOR A;  1WYM A;  1DXX A;  1UJO A;  2K3S A;  2L3G A;  2EYN A;  2JV9 A;  3HOP A;  3JAK M;  4Q57 B;  3I6X A;  1P2X A;  1WYR A;  1V5K A;  4Q59 A;  2VZD A;  5J8E A;  2D85 A;  2R0O A;  2R8U A;  4B7L A;  3F7P A;  2WA5 A;  5A36 A;  2K2R A;  5BVR A;  3FER A;  1AOA A;  1MB8 A;  2QJZ A;  1UEG A;  3HOC A;  1SH5 A;  4EDL A;  4EDN A;  1P5S A;  1BKR A;  5A4B A;  4TXK A;  1WYO A;  2WFN A;  1QAG A;  1WKU A;  4TXI A;  1WYQ A;  5A37 A;  1WYP A; 
#chains in the Genus database with same CATH topology
 1AA2 A;  2EQO A;  3JAR M;  2YRN A;  1PXY A;  1EUV A;  1TJT A;  2D89 A;  3JAL M;  2E9K A;  2WA7 A;  4EDM A;  4LVP A;  2D87 A;  2HKP A;  2DK9 A;  3KY9 A;  2VZG B;  4Q58 A;  1WIX A;  4DDP A;  3KMW B;  2EE7 A;  1VKA A;  2RR8 A;  1WYN A;  1WYL A;  2D86 A;  1PA7 A;  3CO1 A;  5A38 A;  3VP7 A;  1H67 A;  1BHD A;  2WA6 A;  2D88 A;  2WDT A;  1RT8 A;  1WJO A;  2VZC A;  5L0O A;  2VZI B;  2EYI A;  1SH6 A;  2HL9 A;  3REP B;  5FMT A;  2QJX A;  3KMU B;  3HOR A;  1WYM A;  1DXX A;  1UJO A;  2K3S A;  2L3G A;  2EYN A;  2JV9 A;  3HOP A;  2WE6 A;  3JAK M;  4Q57 B;  3I6X A;  1P2X A;  1WYR A;  1V5K A;  4Q59 A;  2VZD A;  2VE7 C;  5J8E A;  3EAY A;  2D85 A;  2R0O A;  2R8U A;  4B7L A;  3F7P A;  2WA5 A;  5A36 A;  2K2R A;  5BVR A;  3FER A;  1AOA A;  1MB8 A;  2QJZ A;  1UEG A;  3HOC A;  1SH5 A;  4EDL A;  4EDN A;  1P5S A;  1BKR A;  5A4B A;  4LVR A;  4TXK A;  1WYO A;  2VE7 A;  1QAG A;  1WKU A;  2WFN A;  4TXI A;  1WYQ A;  2IGP A;  5A37 A;  2HL8 A;  1WYP A;  5FMU A; 
#chains in the Genus database with same CATH homology
 1AA2 A;  3JAR M;  2YRN A;  1PXY A;  1TJT A;  2D89 A;  3JAL M;  2E9K A;  2WA7 A;  4EDM A;  2D87 A;  2DK9 A;  3KY9 A;  2VZG B;  4Q58 A;  1WIX A;  3KMW B;  2EE7 A;  1VKA A;  2RR8 A;  1WYN A;  1WYL A;  2D86 A;  1PA7 A;  3CO1 A;  5A38 A;  1H67 A;  1BHD A;  2WA6 A;  2D88 A;  1RT8 A;  1WJO A;  2VZC A;  5L0O A;  2VZI B;  2EYI A;  1SH6 A;  3REP B;  2QJX A;  3KMU B;  3HOR A;  1WYM A;  1DXX A;  1UJO A;  2K3S A;  2L3G A;  2EYN A;  2JV9 A;  3HOP A;  3JAK M;  4Q57 B;  3I6X A;  1P2X A;  1WYR A;  1V5K A;  4Q59 A;  2VZD A;  5J8E A;  2D85 A;  2R0O A;  2R8U A;  4B7L A;  3F7P A;  2WA5 A;  5A36 A;  2K2R A;  5BVR A;  3FER A;  1AOA A;  1MB8 A;  2QJZ A;  1UEG A;  3HOC A;  1SH5 A;  4EDL A;  4EDN A;  1P5S A;  1BKR A;  5A4B A;  4TXK A;  1WYO A;  2WFN A;  1QAG A;  1WKU A;  4TXI A;  1WYQ A;  5A37 A;  1WYP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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