3JC63

Structure of the eukaryotic replicative cmg helicase and pumpjack motion
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
313
structure length
269
Chain Sequence
DAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
pubmed doi rcsb
molecule tags Replication
source organism Saccharomyces cerevisiae
molecule keywords DNA replication licensing factor MCM2
total genus 45
structure length 269
sequence length 313
ec nomenclature ec 3.6.4.12: DNA helicase.
pdb deposition date 2015-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
3 PF00493 MCM MCM P-loop domain
3 PF17207 MCM_OB MCM OB domain
3 PF17855 MCM_lid MCM AAA-lid domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1640.10 Alpha Beta 2-Layer Sandwich mini-chromosome maintenance (MCM) complex, chain A, domain 1 mini-chromosome maintenance (MCM) complex, chain A, domain 1 3jc6301
5IY0A 4ME3A 4YWMA 4POFA 4POGA 1LTLA 4YWKA 4YWLA 2VL6A 3JC62 3JC63 3JC66
chains in the Genus database with same CATH superfamily
5IY0A 4ME3A 4YWMA 4POFA 4POGA 1LTLA 4YWKA 4YWLA 2VL6A 3JC62 3JC63 3JC66 3F8TA
chains in the Genus database with same CATH topology
5IY0A 4ME3A 4YWMA 4POFA 4POGA 1LTLA 4YWKA 4YWLA 2VL6A 3JC62 3JC63 3JC66 3F8TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IY0 A;  4ME3 A;  4YWM A;  4POF A;  4POG A;  1LTL A;  4YWK A;  4YWL A;  2VL6 A;  3JC6 2;  3JC6 3;  3JC6 6; 
#chains in the Genus database with same CATH topology
 5IY0 A;  4ME3 A;  4YWM A;  4POF A;  4POG A;  1LTL A;  4YWK A;  4YWL A;  2VL6 A;  3JC6 2;  3JC6 3;  3JC6 6;  3F8T A; 
#chains in the Genus database with same CATH homology
 5IY0 A;  4ME3 A;  4YWM A;  4POF A;  4POG A;  1LTL A;  4YWK A;  4YWL A;  2VL6 A;  3JC6 2;  3JC6 3;  3JC6 6;  3F8T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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