3K43A

Crystal structure of scd-mpr mutant e19q/k137m ph 6.5
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
152
structure length
141
Chain Sequence
EKTCDLVGESEKQLALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSECFYLFEMDSSLACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein transport, sugar binding protein
molecule keywords Cation-dependent mannose-6-phosphate receptor
publication title Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.
pubmed doi rcsb
source organism Bos taurus
total genus 36
structure length 141
sequence length 152
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 3k43A00
2RL8A 1E6FA 2KVAA 3K42A 3CY4A 3K41A 2L2AA 1KEOA 2M68A 2V5NA 3AIHA 2RL9A 1Q25A 1GP0A 3K43A 2LLAA 2LVXA 2L21A 1M6PA 2L29A 2M6TA 1GQBA 2KVBA 4XQMA 2N1HA 1SYOA 2RLBA 1C39A 5IEIA 1GP3A 2L2GA 2RL7A 2V5OA 2CNJD 1SZ0A
chains in the Genus database with same CATH superfamily
2RL8A 1E6FA 2KVAA 3K42A 3CY4A 3K41A 2L2AA 1KEOA 2M68A 2V5NA 3AIHA 2RL9A 1Q25A 1GP0A 3K43A 2LLAA 2LVXA 2L21A 1M6PA 2L29A 2M6TA 1GQBA 2KVBA 4XQMA 2N1HA 1SYOA 2RLBA 1C39A 5IEIA 1GP3A 2L2GA 2RL7A 2V5OA 2CNJD 1SZ0A
chains in the Genus database with same CATH topology
2RL8A 1E6FA 2KVAA 3K42A 3CY4A 3K41A 2L2AA 1KEOA 2M68A 2V5NA 3AIHA 2RL9A 1Q25A 1GP0A 3K43A 2LLAA 2LVXA 2L21A 1M6PA 2L29A 2M6TA 1GQBA 2KVBA 4XQMA 2N1HA 1SYOA 2RLBA 1C39A 5IEIA 1GP3A 2L2GA 2RL7A 2V5OA 2CNJD 1SZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RL8 A;  1E6F A;  2KVA A;  3K42 A;  3CY4 A;  3K41 A;  2L2A A;  1KEO A;  2M68 A;  2V5N A;  3AIH A;  2RL9 A;  1Q25 A;  1GP0 A;  3K43 A;  2LLA A;  2LVX A;  2L21 A;  1M6P A;  2L29 A;  2M6T A;  1GQB A;  2KVB A;  4XQM A;  2N1H A;  1SYO A;  2RLB A;  1C39 A;  5IEI A;  1GP3 A;  2L2G A;  2RL7 A;  2V5O A;  2CNJ D;  1SZ0 A; 
#chains in the Genus database with same CATH topology
 2RL8 A;  1E6F A;  2KVA A;  3K42 A;  3CY4 A;  3K41 A;  2L2A A;  1KEO A;  2M68 A;  2V5N A;  3AIH A;  2RL9 A;  1Q25 A;  1GP0 A;  3K43 A;  2LLA A;  2LVX A;  2L21 A;  1M6P A;  2L29 A;  2M6T A;  1GQB A;  2KVB A;  4XQM A;  2N1H A;  1SYO A;  2RLB A;  1C39 A;  5IEI A;  1GP3 A;  2L2G A;  2RL7 A;  2V5O A;  2CNJ D;  1SZ0 A; 
#chains in the Genus database with same CATH homology
 2RL8 A;  1E6F A;  2KVA A;  3K42 A;  3CY4 A;  3K41 A;  2L2A A;  1KEO A;  2M68 A;  2V5N A;  3AIH A;  2RL9 A;  1Q25 A;  1GP0 A;  3K43 A;  2LLA A;  2LVX A;  2L21 A;  1M6P A;  2L29 A;  2M6T A;  1GQB A;  2KVB A;  4XQM A;  2N1H A;  1SYO A;  2RLB A;  1C39 A;  5IEI A;  1GP3 A;  2L2G A;  2RL7 A;  2V5O A;  2CNJ D;  1SZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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