3K7WC

Protein phosphatase 2a core complex bound to dinophysistoxin-2
Total Genus 108
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
288
structure length
288
Chain Sequence
FTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A structural basis for the reduced toxicity of dinophysistoxin-2.
pubmed doi rcsb
molecule keywords Serine/threonine-protein phosphatase 2A 65 kDa regulatory su
source organism Homo sapiens
molecule tags Signaling protein/hydrolase
total genus 108
structure length 288
sequence length 288
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2009-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 3k7wC00
2ZBMA 4KBPA 2DFJA 2IE4C 3AV0A 4NZVA 1OIEA 4YKEA 4G9JA 4DHLA 2NYLC 5JPEA 3THOB 5F3WA 3CK2A 4V0WA 1IT6A 2CV9A 1QHWA 4V0VA 3H68A 2Z1AA 1W24A 4H1SA 3K7VC 3H69A 1S95A 2AHDA 4O24A 3IVEA 3QFKA 5DNYA 4DSYA 4B2OA 5INBA 1Z2XA 4IYPC 3C9FA 1TCOA 2HYOA 1HO5A 3DSCA 3RL5A 4FBWA 3QFNA 4HD0A 3H64A 3DSDA 1XM7A 3ZTVA 3P71C 3THNA 1S3MA 1NNWA 1S70A 3IVDA 3E7BA 3C5WC 3N5UA 2GJUA 4FBQA 4O4KA 1USHA 2Z06A 2BCDA 4UT3B 1Z2WA 4H2GA 2KKNA 3QFMA 4FCXA 4Q7FA 1II7A 3ICFA 1HPUA 2BQ8X 3IB7A 2WDEA 4XPNA 1MF8A 1WAO1 4O5GA 4OR9A 4ZX2A 3ZU0A 4TUGA 2XMOA 1G5BA 1OI8A 2USHA 2QFPA 4H1YP 4LACC 5C1VA 5JJTA 4UWQA 2O8GA 4I5LC 4UT3A 2O8AA 3H60A 4I5NC 2YVTA 3IB8A 3H63A 4MOYA 1KBPA 1OIDA 1U32A 4M0VA 4DT2A 4ORCA 3LL8A 3RL4A 2WDFA 2WDCA 1T70A 2P6BA 1WARA 4MP0A 2R17A 5HPEA 5IOHA 4V0XA 4F0ZA 3QFOA 3PSNA 4LU9A 1XZWA 1JK7A 2IE3C 4ZVZA 5B8IA 2HYPA 5JPFA 4JA7A 3AUZA 1UTEA 3PSOA 2NPPC 4H2IA 1T71A 2QFRA 3TGHA 3JYFA 1QFCA 4ORBA 3GVEA 3K7WC 1HP1A 4J6OA 4ORAA 2WDDA 3H62B 1AUIA 2NYMC 1V73A 4LTYA 1SU1A 3DW8C 3FGAC 2NXFA 3KBPA 5EQVA 3H67A 4FBKA 4H2BA 1FJMA 4O43A 4MOVA 3RQZA 5GTUA 3T1IA 2JOGA 3RL3A 4KKZA 2Z72A 3EGGA 1S8EA 3HVQA 4UT2A 2HY1A 4H2FA 3V4YA 3EGHA 2Q8UA 4WWLA 3QG5C 2A22A 4JA9A 1S3LA 1UF3A 3E7AA 5J28A 4TUIA 2BDXA 4IL1A 1S3NA 3H66A 1M63A 2IAEC 3H61A 2QJCA
chains in the Genus database with same CATH superfamily
2ZBMA 4KBPA 2DFJA 2IE4C 3AV0A 2DXNA 4NZVA 1OIEA 4YKEA 4G9JA 4DHLA 2NYLC 2ZOAA 5JPEA 3THOB 5F3WA 3CK2A 4V0WA 1IT6A 2CV9A 1QHWA 4V0VA 3H68A 2Z1AA 1W24A 4H1SA 3K7VC 3H69A 1S95A 2AHDA 4O24A 3IVEA 3QFKA 5DNYA 4DSYA 4B2OA 5INBA 1Z2XA 4IYPC 3C9FA 1TCOA 2HYOA 1HO5A 3FLOA 3DSCA 3RL5A 4FBWA 3QFNA 4HD0A 3H64A 3DSDA 1XM7A 3ZTVA 3P71C 3THNA 1S3MA 1NNWA 1S70A 3IVDA 3E7BA 3C5WC 3N5UA 2GJUA 4FBQA 4O4KA 1USHA 2Z06A 2BCDA 4UT3B 1Z2WA 4H2GA 2KKNA 3QFMA 4FCXA 4Q7FA 1II7A 3ICFA 1HPUA 2BQ8X 3IB7A 2WDEA 2ZO9B 4XPNA 1MF8A 1WAO1 4O5GA 4OR9A 4ZX2A 3ZU0A 4TUGA 2XMOA 1G5BA 1OI8A 2USHA 2QFPA 4H1YP 4LACC 5C1VA 5JJTA 4UWQA 2O8GA 4I5LC 4UT3A 2O8AA 3H60A 4I5NC 2YVTA 3IB8A 3H63A 4MOYA 1KBPA 1OIDA 1U32A 4M0VA 4DT2A 4ORCA 3LL8A 3RL4A 2WDFA 2WDCA 1T70A 2P6BA 1WARA 4MP0A 2R17A 5HPEA 5IOHA 4V0XA 4F0ZA 3E0JA 3QFOA 3PSNA 4LU9A 1XZWA 1JK7A 2IE3C 4ZVZA 5B8IA 2HYPA 5JPFA 4JA7A 3D03A 3AUZA 1UTEA 3PSOA 2NPPC 4H2IA 1T71A 2QFRA 3TGHA 3JYFA 1QFCA 4ORBA 3GVEA 3K7WC 1HP1A 4J6OA 4ORAA 2WDDA 3H62B 1AUIA 2NYMC 1V73A 4LTYA 1SU1A 3DW8C 3FGAC 2NXFA 3KBPA 5EQVA 3H67A 4FBKA 4H2BA 1FJMA 4O43A 4MOVA 3RQZA 5GTUA 3T1IA 2JOGA 3RL3A 4KKZA 2Z72A 3EGGA 1S8EA 3HVQA 4UT2A 2HY1A 4H2FA 3V4YA 2DXLA 2Q8UA 3EGHA 4WWLA 3QG5C 2A22A 4JA9A 1S3LA 1UF3A 3E7AA 5J28A 4TUIA 2BDXA 2YEQA 4IL1A 1S3NA 3H66A 1M63A 2IAEC 3H61A 2QJCA
chains in the Genus database with same CATH topology
2ZBMA 4KBPA 2DFJA 2IE4C 3AV0A 2DXNA 4NZVA 1OIEA 4YKEA 4G9JA 4DHLA 2NYLC 2ZOAA 5JPEA 3THOB 5F3WA 3CK2A 4V0WA 1IT6A 2CV9A 1QHWA 4V0VA 3H68A 2Z1AA 1W24A 4H1SA 3K7VC 3H69A 1S95A 2AHDA 4O24A 3IVEA 3QFKA 5DNYA 4DSYA 4B2OA 5INBA 1Z2XA 4IYPC 3C9FA 1TCOA 2HYOA 1HO5A 3FLOA 3DSCA 3RL5A 4FBWA 3QFNA 4HD0A 3H64A 3DSDA 1XM7A 3ZTVA 3P71C 3THNA 1S3MA 1NNWA 1S70A 3IVDA 3E7BA 3C5WC 3N5UA 2GJUA 4FBQA 4O4KA 1USHA 2Z06A 2BCDA 4UT3B 1Z2WA 4H2GA 2KKNA 3QFMA 4FCXA 4Q7FA 1II7A 3ICFA 1HPUA 2BQ8X 3IB7A 2WDEA 2ZO9B 4XPNA 1MF8A 1WAO1 4O5GA 4OR9A 4ZX2A 3ZU0A 4TUGA 2XMOA 1G5BA 1OI8A 2USHA 2QFPA 4H1YP 4LACC 5C1VA 5JJTA 4UWQA 2O8GA 4I5LC 4UT3A 2O8AA 3H60A 4I5NC 2YVTA 3IB8A 3H63A 4MOYA 1KBPA 1OIDA 1U32A 4M0VA 4DT2A 4ORCA 3LL8A 3RL4A 2WDFA 2WDCA 1T70A 2P6BA 1WARA 4MP0A 2R17A 5HPEA 5IOHA 4V0XA 4F0ZA 3E0JA 3QFOA 3PSNA 4LU9A 1XZWA 1JK7A 2IE3C 4ZVZA 5B8IA 2HYPA 5JPFA 4JA7A 3D03A 3AUZA 1UTEA 3PSOA 2NPPC 4H2IA 1T71A 2QFRA 3TGHA 3JYFA 1QFCA 4ORBA 3GVEA 3K7WC 1HP1A 4J6OA 4ORAA 2WDDA 3H62B 1AUIA 2NYMC 1V73A 4LTYA 1SU1A 3DW8C 3FGAC 2NXFA 3KBPA 5EQVA 3H67A 4FBKA 4H2BA 1FJMA 4O43A 4MOVA 3RQZA 5GTUA 3T1IA 2JOGA 3RL3A 4KKZA 2Z72A 3EGGA 1S8EA 3HVQA 4UT2A 2HY1A 4H2FA 3V4YA 2DXLA 2Q8UA 3EGHA 4WWLA 3QG5C 2A22A 4JA9A 1S3LA 1UF3A 3E7AA 5J28A 4TUIA 2BDXA 2YEQA 4IL1A 1S3NA 3H66A 1M63A 2IAEC 3H61A 2QJCA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2ZBM A;  4KBP A;  2DFJ A;  2IE4 C;  3AV0 A;  4NZV A;  1OIE A;  4YKE A;  4G9J A;  4DHL A;  2NYL C;  5JPE A;  3THO B;  5F3W A;  3CK2 A;  4V0W A;  1IT6 A;  2CV9 A;  1QHW A;  4V0V A;  3H68 A;  2Z1A A;  1W24 A;  4H1S A;  3K7V C;  3H69 A;  1S95 A;  2AHD A;  4O24 A;  3IVE A;  3QFK A;  5DNY A;  4DSY A;  4B2O A;  5INB A;  1Z2X A;  4IYP C;  3C9F A;  1TCO A;  2HYO A;  1HO5 A;  3DSC A;  3RL5 A;  4FBW A;  3QFN A;  4HD0 A;  3H64 A;  3DSD A;  1XM7 A;  3ZTV A;  3P71 C;  3THN A;  1S3M A;  1NNW A;  1S70 A;  3IVD A;  3E7B A;  3C5W C;  3N5U A;  2GJU A;  4FBQ A;  4O4K A;  1USH A;  2Z06 A;  2BCD A;  4UT3 B;  1Z2W A;  4H2G A;  2KKN A;  3QFM A;  4FCX A;  4Q7F A;  1II7 A;  3ICF A;  1HPU A;  2BQ8 X;  3IB7 A;  2WDE A;  4XPN A;  1MF8 A;  1WAO 1;  4O5G A;  4OR9 A;  4ZX2 A;  3ZU0 A;  4TUG A;  2XMO A;  1G5B A;  1OI8 A;  2USH A;  2QFP A;  4H1Y P;  4LAC C;  5C1V A;  5JJT A;  4UWQ A;  2O8G A;  4I5L C;  4UT3 A;  2O8A A;  3H60 A;  4I5N C;  2YVT A;  3IB8 A;  3H63 A;  4MOY A;  1KBP A;  1OID A;  1U32 A;  4M0V A;  4DT2 A;  4ORC A;  3LL8 A;  3RL4 A;  2WDF A;  2WDC A;  1T70 A;  2P6B A;  1WAR A;  4MP0 A;  2R17 A;  5HPE A;  5IOH A;  4V0X A;  4F0Z A;  3QFO A;  3PSN A;  4LU9 A;  1XZW A;  1JK7 A;  2IE3 C;  4ZVZ A;  5B8I A;  2HYP A;  5JPF A;  4JA7 A;  3AUZ A;  1UTE A;  3PSO A;  2NPP C;  4H2I A;  1T71 A;  2QFR A;  3TGH A;  3JYF A;  1QFC A;  4ORB A;  3GVE A;  3K7W C;  1HP1 A;  4J6O A;  4ORA A;  2WDD A;  3H62 B;  1AUI A;  2NYM C;  1V73 A;  4LTY A;  1SU1 A;  3DW8 C;  3FGA C;  2NXF A;  3KBP A;  5EQV A;  3H67 A;  4FBK A;  4H2B A;  1FJM A;  4O43 A;  4MOV A;  3RQZ A;  5GTU A;  3T1I A;  2JOG A;  3RL3 A;  4KKZ A;  2Z72 A;  3EGG A;  1S8E A;  3HVQ A;  4UT2 A;  2HY1 A;  4H2F A;  3V4Y A;  3EGH A;  2Q8U A;  4WWL A;  3QG5 C;  2A22 A;  4JA9 A;  1S3L A;  1UF3 A;  3E7A A;  5J28 A;  4TUI A;  2BDX A;  4IL1 A;  1S3N A;  3H66 A;  1M63 A;  2IAE C;  3H61 A;  2QJC A; 
#chains in the Genus database with same CATH topology
 2ZBM A;  4KBP A;  2DFJ A;  2IE4 C;  3AV0 A;  2DXN A;  4NZV A;  1OIE A;  4YKE A;  4G9J A;  4DHL A;  2NYL C;  2ZOA A;  5JPE A;  3THO B;  5F3W A;  3CK2 A;  4V0W A;  1IT6 A;  2CV9 A;  1QHW A;  4V0V A;  3H68 A;  2Z1A A;  1W24 A;  4H1S A;  3K7V C;  3H69 A;  1S95 A;  2AHD A;  4O24 A;  3IVE A;  3QFK A;  5DNY A;  4DSY A;  4B2O A;  5INB A;  1Z2X A;  4IYP C;  3C9F A;  1TCO A;  2HYO A;  1HO5 A;  3FLO A;  3DSC A;  3RL5 A;  4FBW A;  3QFN A;  4HD0 A;  3H64 A;  3DSD A;  1XM7 A;  3ZTV A;  3P71 C;  3THN A;  1S3M A;  1NNW A;  1S70 A;  3IVD A;  3E7B A;  3C5W C;  3N5U A;  2GJU A;  4FBQ A;  4O4K A;  1USH A;  2Z06 A;  2BCD A;  4UT3 B;  1Z2W A;  4H2G A;  2KKN A;  3QFM A;  4FCX A;  4Q7F A;  1II7 A;  3ICF A;  1HPU A;  2BQ8 X;  3IB7 A;  2WDE A;  2ZO9 B;  4XPN A;  1MF8 A;  1WAO 1;  4O5G A;  4OR9 A;  4ZX2 A;  3ZU0 A;  4TUG A;  2XMO A;  1G5B A;  1OI8 A;  2USH A;  2QFP A;  4H1Y P;  4LAC C;  5C1V A;  5JJT A;  4UWQ A;  2O8G A;  4I5L C;  4UT3 A;  2O8A A;  3H60 A;  4I5N C;  2YVT A;  3IB8 A;  3H63 A;  4MOY A;  1KBP A;  1OID A;  1U32 A;  4M0V A;  4DT2 A;  4ORC A;  3LL8 A;  3RL4 A;  2WDF A;  2WDC A;  1T70 A;  2P6B A;  1WAR A;  4MP0 A;  2R17 A;  5HPE A;  5IOH A;  4V0X A;  4F0Z A;  3E0J A;  3QFO A;  3PSN A;  4LU9 A;  1XZW A;  1JK7 A;  2IE3 C;  4ZVZ A;  5B8I A;  2HYP A;  5JPF A;  4JA7 A;  3D03 A;  3AUZ A;  1UTE A;  3PSO A;  2NPP C;  4H2I A;  1T71 A;  2QFR A;  3TGH A;  3JYF A;  1QFC A;  4ORB A;  3GVE A;  3K7W C;  1HP1 A;  4J6O A;  4ORA A;  2WDD A;  3H62 B;  1AUI A;  2NYM C;  1V73 A;  4LTY A;  1SU1 A;  3DW8 C;  3FGA C;  2NXF A;  3KBP A;  5EQV A;  3H67 A;  4FBK A;  4H2B A;  1FJM A;  4O43 A;  4MOV A;  3RQZ A;  5GTU A;  3T1I A;  2JOG A;  3RL3 A;  4KKZ A;  2Z72 A;  3EGG A;  1S8E A;  3HVQ A;  4UT2 A;  2HY1 A;  4H2F A;  3V4Y A;  2DXL A;  2Q8U A;  3EGH A;  4WWL A;  3QG5 C;  2A22 A;  4JA9 A;  1S3L A;  1UF3 A;  3E7A A;  5J28 A;  4TUI A;  2BDX A;  2YEQ A;  4IL1 A;  1S3N A;  3H66 A;  1M63 A;  2IAE C;  3H61 A;  2QJC A; 
#chains in the Genus database with same CATH homology
 2ZBM A;  4KBP A;  2DFJ A;  2IE4 C;  3AV0 A;  2DXN A;  4NZV A;  1OIE A;  4YKE A;  4G9J A;  4DHL A;  2NYL C;  2ZOA A;  5JPE A;  3THO B;  5F3W A;  3CK2 A;  4V0W A;  1IT6 A;  2CV9 A;  1QHW A;  4V0V A;  3H68 A;  2Z1A A;  1W24 A;  4H1S A;  3K7V C;  3H69 A;  1S95 A;  2AHD A;  4O24 A;  3IVE A;  3QFK A;  5DNY A;  4DSY A;  4B2O A;  5INB A;  1Z2X A;  4IYP C;  3C9F A;  1TCO A;  2HYO A;  1HO5 A;  3FLO A;  3DSC A;  3RL5 A;  4FBW A;  3QFN A;  4HD0 A;  3H64 A;  3DSD A;  1XM7 A;  3ZTV A;  3P71 C;  3THN A;  1S3M A;  1NNW A;  1S70 A;  3IVD A;  3E7B A;  3C5W C;  3N5U A;  2GJU A;  4FBQ A;  4O4K A;  1USH A;  2Z06 A;  2BCD A;  4UT3 B;  1Z2W A;  4H2G A;  2KKN A;  3QFM A;  4FCX A;  4Q7F A;  1II7 A;  3ICF A;  1HPU A;  2BQ8 X;  3IB7 A;  2WDE A;  2ZO9 B;  4XPN A;  1MF8 A;  1WAO 1;  4O5G A;  4OR9 A;  4ZX2 A;  3ZU0 A;  4TUG A;  2XMO A;  1G5B A;  1OI8 A;  2USH A;  2QFP A;  4H1Y P;  4LAC C;  5C1V A;  5JJT A;  4UWQ A;  2O8G A;  4I5L C;  4UT3 A;  2O8A A;  3H60 A;  4I5N C;  2YVT A;  3IB8 A;  3H63 A;  4MOY A;  1KBP A;  1OID A;  1U32 A;  4M0V A;  4DT2 A;  4ORC A;  3LL8 A;  3RL4 A;  2WDF A;  2WDC A;  1T70 A;  2P6B A;  1WAR A;  4MP0 A;  2R17 A;  5HPE A;  5IOH A;  4V0X A;  4F0Z A;  3E0J A;  3QFO A;  3PSN A;  4LU9 A;  1XZW A;  1JK7 A;  2IE3 C;  4ZVZ A;  5B8I A;  2HYP A;  5JPF A;  4JA7 A;  3D03 A;  3AUZ A;  1UTE A;  3PSO A;  2NPP C;  4H2I A;  1T71 A;  2QFR A;  3TGH A;  3JYF A;  1QFC A;  4ORB A;  3GVE A;  3K7W C;  1HP1 A;  4J6O A;  4ORA A;  2WDD A;  3H62 B;  1AUI A;  2NYM C;  1V73 A;  4LTY A;  1SU1 A;  3DW8 C;  3FGA C;  2NXF A;  3KBP A;  5EQV A;  3H67 A;  4FBK A;  4H2B A;  1FJM A;  4O43 A;  4MOV A;  3RQZ A;  5GTU A;  3T1I A;  2JOG A;  3RL3 A;  4KKZ A;  2Z72 A;  3EGG A;  1S8E A;  3HVQ A;  4UT2 A;  2HY1 A;  4H2F A;  3V4Y A;  2DXL A;  2Q8U A;  3EGH A;  4WWL A;  3QG5 C;  2A22 A;  4JA9 A;  1S3L A;  1UF3 A;  3E7A A;  5J28 A;  4TUI A;  2BDX A;  2YEQ A;  4IL1 A;  1S3N A;  3H66 A;  1M63 A;  2IAE C;  3H61 A;  2QJC A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite