3KECA

Crystal structure of human mmp-13 complexed with a phenyl-2h-tetrazole compound
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
167
structure length
167
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
pubmed doi rcsb
molecule keywords Collagenase 3
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 43
structure length 167
sequence length 167
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-10-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kecA00
3LUMA 2JSDA 2DW0A 3TVCA 5I12A 3VTGA 1AKLA 1OM7A 1QJJA 2X7MA 4GUYA 3LIKA 1A85A 5L79A 1UEAA 4ILWD 1R54A 3HBUP 3EDZA 1SLNA 3AYKA 2OW9A 3LKAA 1FM1A 5B5OA 1OM6A 1PWVA 2W15A 1PWWA 2V4BA 4GR8A 2MLRA 1IADA 1MNCA 4WF6A 3G42A 2MZIA 3HYGA 1SRPA 1EB6A 3HDAP 1BKCI 4PKUA 2PJTA 1Y93A 1MMBA 1Y0VA 1XFUA 1KAPP 1IAAA 1BQOA 5B5PA 1JAPA 1JIZA 5CUHA 1O0TA 2K9CA 1JAQA 1BKCA 1BUVM 3LQBA 1JANA 4FU4A 1AYKA 1G05A 4H84A 1HFCA 1O0QA 1XURA 4PKTA 1ZXCA 1G12A 2FV9A 1ZS0A 3KMCA 4L63A 1XFXA 1GE5A 1KUHA 1QIBA 2JT6A 2MZEA 2X3AA 830CA 3NX7A 4XM8A 5D1TA 3HDBA 3EDIA 3L0TA 1C7KA 4PKVA 4H82A 2YB9A 4WKIA 2J0TA 1HY7A 1JAOA 2MLSA 3LILA 1UTZA 1GO8P 4IUWA 4DPEA 1G49A 3KEJA 3AIGA 1I73A 3N2VA 2SRTA 1GE6A 3N2UA 1D7XA 1SLMA 2W0DA 2OI0A 5BOYA 3V96B 3DPEA 3LIRA 2OW1A 2CKIA 2OY4A 1QJIA 1GKCA 5D7WA 1BSWA 3BA0A 1YQYA 1D5JA 2Z2DA 3K7NA 4AIGA 5H8XA 3O64A 5L7FA 4XM7A 2OVXA 3USNA 4ON1A 4J4MA 3DSLA 1ZVXA 1I76A 2RJQA 1KUKA 4ZR5A 3TT4A 2DW1A 2USNA 4JA1A 2OXUA 1CGFA 2YIGA 1JKYA 4WKEA 2Y6CA 3AYUA 4JIJA 3HB2P 1XFZA 3KECA 4JP4A 4H30A 2QPJA 3EDHA 2OXZA 4QKZA 3I7IA 4G9LA 5JMYA 1MMPA 3G5CA 3OHOA 4I35A 1ND1A 2N8RA 2E3XA 3TS4A 1HFSA 1XFWA 1YCMA 1Z3JA 966CA 4PKQA 1PWPA 3GBOA 1BZSA 1QIAA 2KRJA 3F19A 4GQLA 2WO9A 4CTHA 3LK8A 3KMEA 3HBVP 4WK7A 1BKCE 2K2GA 4GWNA 3WV1A 1KUIA 3B2ZA 3B8ZA 4AYKA 5I0LA 1H71P 1BQQM 1C8TA 5I3MA 2TCLA 1BM6A 2OW2A 4L6TA 3LUNA 3E8RA 4DD8A 1G4KA 1RMZA 1GE7A 3VI1A 1SU3A 1CGLA 2POJA 2WOAA 4H3XA 4GR0A 4IJOA 2D1NA 4XM6A 1UTTA 4PKRA 4AXQA 2FV5A 3EDGA 3LEAA 3CKIA 3I7GA 1JH1A 1YP1A 3F1AA 1YOUA 4H49A 4XCTA 3SHIA 2DDFA 2OVZA 1MMQA 1R55A 4DF9A 2OZRA 5D1UA 4GF1A 1R1IA 1ZXVA 3ZUKA 1WNIA 3EHYA 3EWJA 1DMTA 5LABA 5I43A 2I47A 5D2BA 3RTSA 3LJTA 1OS2A 3OHLA 1J7NA 1R1JA 3Q2GA 4FXQA 2X3CA 3P1VA 4Q1LA 4L19A 3UVCA 2E2DA 1B3DA 4FVLA 1KUFA 1G9KA 1KUGA 4HX3A 1Q3AA 4AUOA 3U1RA 4H76A 1GO7P 1RM8A 3K7LA 3F18A 1D8MA 5D1SA 3TSKA 4GR3A 4A7BA 1IAEA 1Y8JA 4JPAA 4H1QA 3KEKA 5BOTA 1C3IA 1CXVA 4DV8A 3DL1A 2J83A 1ASTA 1B8YA 1ATLA 1HV5A 1HTDA 1CIZA 3MA2A 2OXWA 1SMPA 1DTHA 3WV3A 5I2ZA 2OW0A 2W12A 4G0DA 1CGEA 4H2EA 3WV2A 1MMRA 1CAQA 3KHIA 5I4OA 4R3VA 4WZVA 3KRYA 1CQRA 3DNGA 3O2XA 4EFSA 3ZXHA 3ELMA 2W13A 2ERPA 1S4BP 5CZMA 1XFYA 5CXAA 1XUDA 4I03A 3P24A 1IAGA 1HOVA 1ZTQA 3RTTA 1K7GA 1GXDA 2AIGP 3LMCA 3DPFA 1I1IP 2MZHA 4HMAA 3F16A 2XS4A 1AF0A 1BUDA 2W14A 1IACA 1FBLA 1GKDA 2Y6DA 1XFVA 3LJZA 3F15A 1PWUA 1OS9A 1QUAA 2HU6A 2JIHA 1QICA 2D1OA 3Q2HA 3LGPA 2WO8A 1A86A 1KBCA 1USNA 2L0RA 4PKSA 1JK3A 3LQ0A 3B92A 3DWBA 1L6JA 1CK7A 2A8HA 1OM8A 2DW2A 3HY7A 2JNPA 4IN9A 3EHXA 4JQGA 1JJ9A 1PWQA 1SATA 1D8FA 1K7IA 1JIWP 3LJGA 2DDYA 4PKWA 2RJPA 1K7QA 4XBHA 1EAKA 4GWMA 3LE9A 2EROA 2XS3A 3L0VA 1IABA 1XUCA 2CLTA 1BIWA 2ERQA 1EUBA 5D3CA 2AYKA 456CA 3KWVC 5BPAA 2O36A 4FXYP 1OMJA 2X3BA 2OY2A 2O3EA 1OO9A 3HY9A 1UMSA 1UMTA 1ROSA 3ZVSA 4A3WA 1ZP5A 1R1HA 1FLSA 3F17A 2JT5A
chains in the Genus database with same CATH superfamily
3LUMA 2JSDA 2DW0A 3TVCA 5I12A 3VTGA 1AKLA 1OM7A 1QJJA 2X7MA 4GUYA 3LIKA 1A85A 5L79A 1UEAA 4ILWD 1R54A 3HBUP 3EDZA 1SLNA 3AYKA 2OW9A 3LKAA 1FM1A 5B5OA 1OM6A 1PWVA 2W15A 1PWWA 2V4BA 4GR8A 2MLRA 1IADA 1MNCA 4WF6A 3G42A 2MZIA 3HYGA 1SRPA 1EB6A 3HDAP 1BKCI 4PKUA 2PJTA 1Y93A 1MMBA 1Y0VA 1XFUA 1KAPP 1IAAA 1BQOA 5B5PA 1JAPA 1JIZA 5CUHA 1O0TA 2K9CA 1JAQA 1BKCA 1BUVM 3LQBA 1JANA 4FU4A 1AYKA 1G05A 4H84A 1HFCA 1O0QA 1XURA 4PKTA 1ZXCA 1G12A 2FV9A 1ZS0A 3KMCA 4L63A 1XFXA 1GE5A 1KUHA 1QIBA 2JT6A 2MZEA 2X3AA 830CA 3NX7A 4XM8A 5D1TA 3HDBA 3EDIA 3L0TA 1C7KA 4PKVA 4H82A 2YB9A 4WKIA 2J0TA 1HY7A 1JAOA 2MLSA 3LILA 1UTZA 1GO8P 4IUWA 4DPEA 1G49A 3KEJA 3AIGA 1I73A 3N2VA 2SRTA 1GE6A 3N2UA 1D7XA 1SLMA 2W0DA 2OI0A 5BOYA 3V96B 3DPEA 3LIRA 2OW1A 2CKIA 2OY4A 1QJIA 1GKCA 5D7WA 1BSWA 3BA0A 1YQYA 1D5JA 2Z2DA 3K7NA 4AIGA 5H8XA 3O64A 5L7FA 4XM7A 2OVXA 3USNA 4ON1A 4J4MA 3DSLA 1ZVXA 1I76A 2RJQA 1KUKA 4ZR5A 3TT4A 2DW1A 2USNA 4JA1A 2OXUA 1CGFA 2YIGA 1JKYA 4WKEA 2Y6CA 3AYUA 4JIJA 3HB2P 1XFZA 3KECA 4JP4A 4H30A 2QPJA 3EDHA 2OXZA 4QKZA 3I7IA 4G9LA 5JMYA 1MMPA 3G5CA 3OHOA 4I35A 1ND1A 2N8RA 2E3XA 3TS4A 1HFSA 1XFWA 1YCMA 1Z3JA 966CA 4PKQA 1PWPA 3GBOA 1BZSA 1QIAA 2KRJA 3F19A 4GQLA 2WO9A 4CTHA 3LK8A 3KMEA 3HBVP 4WK7A 1BKCE 2K2GA 4GWNA 3WV1A 1KUIA 3B2ZA 3B8ZA 4AYKA 5I0LA 1H71P 1BQQM 1C8TA 5I3MA 2TCLA 1BM6A 2OW2A 4L6TA 3LUNA 3E8RA 4DD8A 1G4KA 1RMZA 1GE7A 3VI1A 1SU3A 1CGLA 2POJA 2WOAA 4H3XA 4GR0A 4IJOA 2D1NA 4XM6A 1UTTA 4PKRA 4AXQA 2FV5A 3EDGA 3LEAA 3CKIA 3I7GA 1JH1A 1YP1A 3F1AA 1YOUA 4H49A 4XCTA 3SHIA 2DDFA 2OVZA 1MMQA 1R55A 4DF9A 2OZRA 5D1UA 1XM5A 4GF1A 1R1IA 1ZXVA 3ZUKA 1WNIA 3EHYA 3EWJA 1DMTA 5LABA 5I43A 2I47A 5D2BA 3RTSA 3LJTA 1OS2A 3OHLA 1J7NA 1R1JA 3Q2GA 4FXQA 2X3CA 3P1VA 4Q1LA 4L19A 3UVCA 2E2DA 1B3DA 4FVLA 1KUFA 1G9KA 1KUGA 4HX3A 1Q3AA 4AUOA 3U1RA 4H76A 1GO7P 1RM8A 3K7LA 3F18A 1D8MA 5D1SA 3TSKA 4GR3A 4A7BA 1IAEA 1Y8JA 4JPAA 4H1QA 3KEKA 5BOTA 1C3IA 1CXVA 4DV8A 3DL1A 2J83A 1ASTA 1B8YA 1ATLA 1HV5A 1HTDA 3DTIA 1CIZA 3DTEA 3MA2A 2OXWA 1SMPA 3DTKA 1DTHA 3WV3A 5I2ZA 2OW0A 2W12A 4G0DA 1CGEA 4H2EA 3WV2A 1MMRA 1CAQA 3KHIA 5I4OA 4R3VA 4WZVA 3KRYA 1CQRA 3DNGA 3O2XA 4EFSA 3ZXHA 3ELMA 2W13A 2ERPA 1S4BP 5CZMA 1XFYA 5CXAA 1XUDA 4I03A 3P24A 1IAGA 1HOVA 1ZTQA 3RTTA 1K7GA 1GXDA 2AIGP 3LMCA 3DPFA 1I1IP 2MZHA 4HMAA 3F16A 2XS4A 1AF0A 1BUDA 2W14A 1IACA 1FBLA 1GKDA 2Y6DA 1XFVA 3LJZA 3F15A 1PWUA 1OS9A 1QUAA 2HU6A 2JIHA 1QICA 2D1OA 3Q2HA 3LGPA 2WO8A 1A86A 1TVIA 1KBCA 1USNA 2L0RA 4PKSA 1JK3A 3LQ0A 3B92A 3DWBA 1L6JA 1CK7A 2A8HA 1OM8A 2DW2A 1OZ9A 3HY7A 2JNPA 4IN9A 3EHXA 4JQGA 1JJ9A 1PWQA 1SATA 1D8FA 1XAXA 1K7IA 1JIWP 3LJGA 2DDYA 4PKWA 2RJPA 1K7QA 4XBHA 1EAKA 4GWMA 3LE9A 2EROA 4L7AA 2XS3A 3L0VA 1IABA 1XUCA 2CLTA 1BIWA 2ERQA 1EUBA 5D3CA 2AYKA 456CA 3KWVC 5BPAA 2O36A 4FXYP 1OMJA 2X3BA 2OY2A 2O3EA 1OO9A 3HY9A 1UMSA 2YUFA 1UMTA 1ROSA 3ZVSA 4A3WA 1ZP5A 1R1HA 1FLSA 3F17A 2JT5A
chains in the Genus database with same CATH topology
3LUMA 2JSDA 2DW0A 3TVCA 5I12A 3VTGA 1AKLA 1OM7A 1QJJA 2X7MA 4GUYA 3LIKA 1A85A 5L79A 1UEAA 4ILWD 1R54A 3HBUP 3EDZA 1SLNA 3AYKA 2OW9A 3LKAA 1FM1A 5B5OA 1OM6A 1PWVA 2W15A 1PWWA 2V4BA 4GR8A 2MLRA 1IADA 1MNCA 4WF6A 3G42A 2MZIA 3HYGA 1SRPA 1EB6A 3HDAP 1BKCI 4PKUA 2PJTA 1Y93A 1MMBA 1Y0VA 1XFUA 1KAPP 1IAAA 1BQOA 5B5PA 1JAPA 1JIZA 5CUHA 1O0TA 2K9CA 1JAQA 1BKCA 1BUVM 3LQBA 1JANA 4FU4A 1AYKA 1G05A 4H84A 1HFCA 1O0QA 1XURA 4PKTA 1ZXCA 1G12A 2FV9A 1ZS0A 3KMCA 4L63A 1XFXA 1GE5A 1KUHA 1QIBA 2JT6A 2MZEA 2X3AA 830CA 3NX7A 4XM8A 5D1TA 3HDBA 3EDIA 3L0TA 1C7KA 4PKVA 4H82A 2YB9A 4WKIA 2J0TA 1HY7A 1JAOA 2MLSA 3LILA 1UTZA 1GO8P 4IUWA 4DPEA 1G49A 3KEJA 3AIGA 1I73A 3N2VA 2SRTA 1GE6A 3N2UA 1D7XA 1SLMA 2W0DA 2OI0A 5BOYA 3V96B 3DPEA 3LIRA 2OW1A 2CKIA 2OY4A 1QJIA 1GKCA 5D7WA 1BSWA 3BA0A 1YQYA 1D5JA 2Z2DA 3K7NA 4AIGA 5H8XA 3O64A 5L7FA 4XM7A 2OVXA 3USNA 4ON1A 4J4MA 3DSLA 1ZVXA 1I76A 2RJQA 1KUKA 4ZR5A 3TT4A 2DW1A 2USNA 4JA1A 2OXUA 1CGFA 2YIGA 1JKYA 4WKEA 2Y6CA 3AYUA 4JIJA 3HB2P 1XFZA 3KECA 4JP4A 4H30A 2QPJA 3EDHA 2OXZA 4QKZA 3I7IA 4G9LA 5JMYA 1MMPA 3G5CA 3OHOA 4I35A 1ND1A 2N8RA 2E3XA 3TS4A 1HFSA 1XFWA 1YCMA 1Z3JA 966CA 4PKQA 1PWPA 3GBOA 1BZSA 1QIAA 2KRJA 3F19A 4GQLA 2WO9A 4CTHA 3LK8A 3KMEA 3HBVP 4WK7A 1BKCE 2K2GA 4GWNA 3WV1A 1KUIA 3B2ZA 3B8ZA 4AYKA 5I0LA 1H71P 1BQQM 1C8TA 5I3MA 2TCLA 1BM6A 2OW2A 4L6TA 3LUNA 3E8RA 4DD8A 1G4KA 1RMZA 1GE7A 3VI1A 1SU3A 1CGLA 2POJA 2WOAA 4H3XA 4GR0A 4IJOA 2D1NA 4XM6A 1UTTA 4PKRA 4AXQA 2FV5A 3EDGA 3LEAA 3CKIA 3I7GA 1JH1A 1YP1A 3F1AA 1YOUA 4H49A 4XCTA 3SHIA 2DDFA 2OVZA 1MMQA 1R55A 4DF9A 2OZRA 5D1UA 4GF1A 1R1IA 1ZXVA 3ZUKA 1WNIA 3EHYA 3EWJA 1DMTA 5LABA 5I43A 2I47A 5D2BA 3RTSA 3LJTA 1OS2A 3OHLA 1J7NA 1R1JA 3Q2GA 4FXQA 2X3CA 3P1VA 4Q1LA 4L19A 3UVCA 2E2DA 1B3DA 4FVLA 1KUFA 1G9KA 1KUGA 4HX3A 1Q3AA 4AUOA 3U1RA 4H76A 1GO7P 1RM8A 3K7LA 3F18A 1D8MA 5D1SA 3TSKA 4GR3A 4A7BA 1IAEA 1Y8JA 4JPAA 4H1QA 3KEKA 5BOTA 1C3IA 1CXVA 4DV8A 3DL1A 2J83A 1ASTA 1B8YA 1ATLA 1HV5A 1HTDA 3DTIA 1CIZA 3DTEA 3MA2A 2OXWA 1SMPA 3DTKA 1DTHA 3WV3A 5I2ZA 2OW0A 2W12A 4G0DA 1CGEA 4H2EA 3WV2A 1MMRA 1CAQA 3KHIA 5I4OA 4R3VA 4WZVA 3KRYA 1CQRA 3DNGA 3O2XA 4EFSA 3ZXHA 3ELMA 2W13A 2ERPA 1S4BP 5CZMA 1XFYA 5CXAA 1XUDA 4I03A 3P24A 1IAGA 1HOVA 1ZTQA 3RTTA 1K7GA 1GXDA 2AIGP 3LMCA 3DPFA 1I1IP 2MZHA 4HMAA 3F16A 2XS4A 1AF0A 1BUDA 2W14A 1IACA 1FBLA 1GKDA 2Y6DA 1XFVA 3LJZA 3F15A 1PWUA 1OS9A 1QUAA 2HU6A 2JIHA 1QICA 2D1OA 3Q2HA 3LGPA 2WO8A 1A86A 1KBCA 1USNA 2L0RA 4PKSA 1JK3A 3LQ0A 3B92A 3DWBA 1L6JA 1CK7A 2A8HA 1OM8A 2DW2A 3HY7A 2JNPA 4IN9A 3EHXA 4JQGA 1JJ9A 1PWQA 1SATA 1D8FA 1K7IA 1JIWP 3LJGA 2DDYA 4PKWA 2RJPA 1K7QA 4XBHA 1EAKA 4GWMA 3LE9A 2EROA 4L7AA 2XS3A 3L0VA 1IABA 1XUCA 2CLTA 1BIWA 2ERQA 1EUBA 5D3CA 2AYKA 456CA 3KWVC 5BPAA 2O36A 4FXYP 1OMJA 2X3BA 2OY2A 2O3EA 1OO9A 3HY9A 1UMSA 2YUFA 1UMTA 1ROSA 3ZVSA 4A3WA 1ZP5A 1R1HA 1FLSA 3F17A 2JT5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LUM A;  2JSD A;  2DW0 A;  3TVC A;  5I12 A;  3VTG A;  1AKL A;  1OM7 A;  1QJJ A;  2X7M A;  4GUY A;  3LIK A;  1A85 A;  5L79 A;  1UEA A;  4ILW D;  1R54 A;  3HBU P;  3EDZ A;  1SLN A;  3AYK A;  2OW9 A;  3LKA A;  1FM1 A;  5B5O A;  1OM6 A;  1PWV A;  2W15 A;  1PWW A;  2V4B A;  4GR8 A;  2MLR A;  1IAD A;  1MNC A;  4WF6 A;  3G42 A;  2MZI A;  3HYG A;  1SRP A;  1EB6 A;  3HDA P;  1BKC I;  4PKU A;  2PJT A;  1Y93 A;  1MMB A;  1Y0V A;  1XFU A;  1KAP P;  1IAA A;  1BQO A;  5B5P A;  1JAP A;  1JIZ A;  5CUH A;  1O0T A;  2K9C A;  1JAQ A;  1BKC A;  1BUV M;  3LQB A;  1JAN A;  4FU4 A;  1AYK A;  1G05 A;  4H84 A;  1HFC A;  1O0Q A;  1XUR A;  4PKT A;  1ZXC A;  1G12 A;  2FV9 A;  1ZS0 A;  3KMC A;  4L63 A;  1XFX A;  1GE5 A;  1KUH A;  1QIB A;  2JT6 A;  2MZE A;  2X3A A;  830C A;  3NX7 A;  4XM8 A;  5D1T A;  3HDB A;  3EDI A;  3L0T A;  1C7K A;  4PKV A;  4H82 A;  2YB9 A;  4WKI A;  2J0T A;  1HY7 A;  1JAO A;  2MLS A;  3LIL A;  1UTZ A;  1GO8 P;  4IUW A;  4DPE A;  1G49 A;  3KEJ A;  3AIG A;  1I73 A;  3N2V A;  2SRT A;  1GE6 A;  3N2U A;  1D7X A;  1SLM A;  2W0D A;  2OI0 A;  5BOY A;  3V96 B;  3DPE A;  3LIR A;  2OW1 A;  2CKI A;  2OY4 A;  1QJI A;  1GKC A;  5D7W A;  1BSW A;  3BA0 A;  1YQY A;  1D5J A;  2Z2D A;  3K7N A;  4AIG A;  5H8X A;  3O64 A;  5L7F A;  4XM7 A;  2OVX A;  3USN A;  4ON1 A;  4J4M A;  3DSL A;  1ZVX A;  1I76 A;  2RJQ A;  1KUK A;  4ZR5 A;  3TT4 A;  2DW1 A;  2USN A;  4JA1 A;  2OXU A;  1CGF A;  2YIG A;  1JKY A;  4WKE A;  2Y6C A;  3AYU A;  4JIJ A;  3HB2 P;  1XFZ A;  3KEC A;  4JP4 A;  4H30 A;  2QPJ A;  3EDH A;  2OXZ A;  4QKZ A;  3I7I A;  4G9L A;  5JMY A;  1MMP A;  3G5C A;  3OHO A;  4I35 A;  1ND1 A;  2N8R A;  2E3X A;  3TS4 A;  1HFS A;  1XFW A;  1YCM A;  1Z3J A;  966C A;  4PKQ A;  1PWP A;  3GBO A;  1BZS A;  1QIA A;  2KRJ A;  3F19 A;  4GQL A;  2WO9 A;  4CTH A;  3LK8 A;  3KME A;  3HBV P;  4WK7 A;  1BKC E;  2K2G A;  4GWN A;  3WV1 A;  1KUI A;  3B2Z A;  3B8Z A;  4AYK A;  5I0L A;  1H71 P;  1BQQ M;  1C8T A;  5I3M A;  2TCL A;  1BM6 A;  2OW2 A;  4L6T A;  3LUN A;  3E8R A;  4DD8 A;  1G4K A;  1RMZ A;  1GE7 A;  3VI1 A;  1SU3 A;  1CGL A;  2POJ A;  2WOA A;  4H3X A;  4GR0 A;  4IJO A;  2D1N A;  4XM6 A;  1UTT A;  4PKR A;  4AXQ A;  2FV5 A;  3EDG A;  3LEA A;  3CKI A;  3I7G A;  1JH1 A;  1YP1 A;  3F1A A;  1YOU A;  4H49 A;  4XCT A;  3SHI A;  2DDF A;  2OVZ A;  1MMQ A;  1R55 A;  4DF9 A;  2OZR A;  5D1U A;  4GF1 A;  1R1I A;  1ZXV A;  3ZUK A;  1WNI A;  3EHY A;  3EWJ A;  1DMT A;  5LAB A;  5I43 A;  2I47 A;  5D2B A;  3RTS A;  3LJT A;  1OS2 A;  3OHL A;  1J7N A;  1R1J A;  3Q2G A;  4FXQ A;  2X3C A;  3P1V A;  4Q1L A;  4L19 A;  3UVC A;  2E2D A;  1B3D A;  4FVL A;  1KUF A;  1G9K A;  1KUG A;  4HX3 A;  1Q3A A;  4AUO A;  3U1R A;  4H76 A;  1GO7 P;  1RM8 A;  3K7L A;  3F18 A;  1D8M A;  5D1S A;  3TSK A;  4GR3 A;  4A7B A;  1IAE A;  1Y8J A;  4JPA A;  4H1Q A;  3KEK A;  5BOT A;  1C3I A;  1CXV A;  4DV8 A;  3DL1 A;  2J83 A;  1AST A;  1B8Y A;  1ATL A;  1HV5 A;  1HTD A;  1CIZ A;  3MA2 A;  2OXW A;  1SMP A;  1DTH A;  3WV3 A;  5I2Z A;  2OW0 A;  2W12 A;  4G0D A;  1CGE A;  4H2E A;  3WV2 A;  1MMR A;  1CAQ A;  3KHI A;  5I4O A;  4R3V A;  4WZV A;  3KRY A;  1CQR A;  3DNG A;  3O2X A;  4EFS A;  3ZXH A;  3ELM A;  2W13 A;  2ERP A;  1S4B P;  5CZM A;  1XFY A;  5CXA A;  1XUD A;  4I03 A;  3P24 A;  1IAG A;  1HOV A;  1ZTQ A;  3RTT A;  1K7G A;  1GXD A;  2AIG P;  3LMC A;  3DPF A;  1I1I P;  2MZH A;  4HMA A;  3F16 A;  2XS4 A;  1AF0 A;  1BUD A;  2W14 A;  1IAC A;  1FBL A;  1GKD A;  2Y6D A;  1XFV A;  3LJZ A;  3F15 A;  1PWU A;  1OS9 A;  1QUA A;  2HU6 A;  2JIH A;  1QIC A;  2D1O A;  3Q2H A;  3LGP A;  2WO8 A;  1A86 A;  1KBC A;  1USN A;  2L0R A;  4PKS A;  1JK3 A;  3LQ0 A;  3B92 A;  3DWB A;  1L6J A;  1CK7 A;  2A8H A;  1OM8 A;  2DW2 A;  3HY7 A;  2JNP A;  4IN9 A;  3EHX A;  4JQG A;  1JJ9 A;  1PWQ A;  1SAT A;  1D8F A;  1K7I A;  1JIW P;  3LJG A;  2DDY A;  4PKW A;  2RJP A;  1K7Q A;  4XBH A;  1EAK A;  4GWM A;  3LE9 A;  2ERO A;  2XS3 A;  3L0V A;  1IAB A;  1XUC A;  2CLT A;  1BIW A;  2ERQ A;  1EUB A;  5D3C A;  2AYK A;  456C A;  3KWV C;  5BPA A;  2O36 A;  4FXY P;  1OMJ A;  2X3B A;  2OY2 A;  2O3E A;  1OO9 A;  3HY9 A;  1UMS A;  1UMT A;  1ROS A;  3ZVS A;  4A3W A;  1ZP5 A;  1R1H A;  1FLS A;  3F17 A;  2JT5 A; 
#chains in the Genus database with same CATH topology
 3LUM A;  2JSD A;  2DW0 A;  3TVC A;  5I12 A;  3VTG A;  1AKL A;  1OM7 A;  1QJJ A;  2X7M A;  4GUY A;  3LIK A;  1A85 A;  5L79 A;  1UEA A;  4ILW D;  1R54 A;  3HBU P;  3EDZ A;  1SLN A;  3AYK A;  2OW9 A;  3LKA A;  1FM1 A;  5B5O A;  1OM6 A;  1PWV A;  2W15 A;  1PWW A;  2V4B A;  4GR8 A;  2MLR A;  1IAD A;  1MNC A;  4WF6 A;  3G42 A;  2MZI A;  3HYG A;  1SRP A;  1EB6 A;  3HDA P;  1BKC I;  4PKU A;  2PJT A;  1Y93 A;  1MMB A;  1Y0V A;  1XFU A;  1KAP P;  1IAA A;  1BQO A;  5B5P A;  1JAP A;  1JIZ A;  5CUH A;  1O0T A;  2K9C A;  1JAQ A;  1BKC A;  1BUV M;  3LQB A;  1JAN A;  4FU4 A;  1AYK A;  1G05 A;  4H84 A;  1HFC A;  1O0Q A;  1XUR A;  4PKT A;  1ZXC A;  1G12 A;  2FV9 A;  1ZS0 A;  3KMC A;  4L63 A;  1XFX A;  1GE5 A;  1KUH A;  1QIB A;  2JT6 A;  2MZE A;  2X3A A;  830C A;  3NX7 A;  4XM8 A;  5D1T A;  3HDB A;  3EDI A;  3L0T A;  1C7K A;  4PKV A;  4H82 A;  2YB9 A;  4WKI A;  2J0T A;  1HY7 A;  1JAO A;  2MLS A;  3LIL A;  1UTZ A;  1GO8 P;  4IUW A;  4DPE A;  1G49 A;  3KEJ A;  3AIG A;  1I73 A;  3N2V A;  2SRT A;  1GE6 A;  3N2U A;  1D7X A;  1SLM A;  2W0D A;  2OI0 A;  5BOY A;  3V96 B;  3DPE A;  3LIR A;  2OW1 A;  2CKI A;  2OY4 A;  1QJI A;  1GKC A;  5D7W A;  1BSW A;  3BA0 A;  1YQY A;  1D5J A;  2Z2D A;  3K7N A;  4AIG A;  5H8X A;  3O64 A;  5L7F A;  4XM7 A;  2OVX A;  3USN A;  4ON1 A;  4J4M A;  3DSL A;  1ZVX A;  1I76 A;  2RJQ A;  1KUK A;  4ZR5 A;  3TT4 A;  2DW1 A;  2USN A;  4JA1 A;  2OXU A;  1CGF A;  2YIG A;  1JKY A;  4WKE A;  2Y6C A;  3AYU A;  4JIJ A;  3HB2 P;  1XFZ A;  3KEC A;  4JP4 A;  4H30 A;  2QPJ A;  3EDH A;  2OXZ A;  4QKZ A;  3I7I A;  4G9L A;  5JMY A;  1MMP A;  3G5C A;  3OHO A;  4I35 A;  1ND1 A;  2N8R A;  2E3X A;  3TS4 A;  1HFS A;  1XFW A;  1YCM A;  1Z3J A;  966C A;  4PKQ A;  1PWP A;  3GBO A;  1BZS A;  1QIA A;  2KRJ A;  3F19 A;  4GQL A;  2WO9 A;  4CTH A;  3LK8 A;  3KME A;  3HBV P;  4WK7 A;  1BKC E;  2K2G A;  4GWN A;  3WV1 A;  1KUI A;  3B2Z A;  3B8Z A;  4AYK A;  5I0L A;  1H71 P;  1BQQ M;  1C8T A;  5I3M A;  2TCL A;  1BM6 A;  2OW2 A;  4L6T A;  3LUN A;  3E8R A;  4DD8 A;  1G4K A;  1RMZ A;  1GE7 A;  3VI1 A;  1SU3 A;  1CGL A;  2POJ A;  2WOA A;  4H3X A;  4GR0 A;  4IJO A;  2D1N A;  4XM6 A;  1UTT A;  4PKR A;  4AXQ A;  2FV5 A;  3EDG A;  3LEA A;  3CKI A;  3I7G A;  1JH1 A;  1YP1 A;  3F1A A;  1YOU A;  4H49 A;  4XCT A;  3SHI A;  2DDF A;  2OVZ A;  1MMQ A;  1R55 A;  4DF9 A;  2OZR A;  5D1U A;  1XM5 A;  4GF1 A;  1R1I A;  1ZXV A;  3ZUK A;  1WNI A;  3EHY A;  3EWJ A;  1DMT A;  5LAB A;  5I43 A;  2I47 A;  5D2B A;  3RTS A;  3LJT A;  1OS2 A;  3OHL A;  1J7N A;  1R1J A;  3Q2G A;  4FXQ A;  2X3C A;  3P1V A;  4Q1L A;  4L19 A;  3UVC A;  2E2D A;  1B3D A;  4FVL A;  1KUF A;  1G9K A;  1KUG A;  4HX3 A;  1Q3A A;  4AUO A;  3U1R A;  4H76 A;  1GO7 P;  1RM8 A;  3K7L A;  3F18 A;  1D8M A;  5D1S A;  3TSK A;  4GR3 A;  4A7B A;  1IAE A;  1Y8J A;  4JPA A;  4H1Q A;  3KEK A;  5BOT A;  1C3I A;  1CXV A;  4DV8 A;  3DL1 A;  2J83 A;  1AST A;  1B8Y A;  1ATL A;  1HV5 A;  1HTD A;  3DTI A;  1CIZ A;  3DTE A;  3MA2 A;  2OXW A;  1SMP A;  3DTK A;  1DTH A;  3WV3 A;  5I2Z A;  2OW0 A;  2W12 A;  4G0D A;  1CGE A;  4H2E A;  3WV2 A;  1MMR A;  1CAQ A;  3KHI A;  5I4O A;  4R3V A;  4WZV A;  3KRY A;  1CQR A;  3DNG A;  3O2X A;  4EFS A;  3ZXH A;  3ELM A;  2W13 A;  2ERP A;  1S4B P;  5CZM A;  1XFY A;  5CXA A;  1XUD A;  4I03 A;  3P24 A;  1IAG A;  1HOV A;  1ZTQ A;  3RTT A;  1K7G A;  1GXD A;  2AIG P;  3LMC A;  3DPF A;  1I1I P;  2MZH A;  4HMA A;  3F16 A;  2XS4 A;  1AF0 A;  1BUD A;  2W14 A;  1IAC A;  1FBL A;  1GKD A;  2Y6D A;  1XFV A;  3LJZ A;  3F15 A;  1PWU A;  1OS9 A;  1QUA A;  2HU6 A;  2JIH A;  1QIC A;  2D1O A;  3Q2H A;  3LGP A;  2WO8 A;  1A86 A;  1TVI A;  1KBC A;  1USN A;  2L0R A;  4PKS A;  1JK3 A;  3LQ0 A;  3B92 A;  3DWB A;  1L6J A;  1CK7 A;  2A8H A;  1OM8 A;  2DW2 A;  1OZ9 A;  3HY7 A;  2JNP A;  4IN9 A;  3EHX A;  4JQG A;  1JJ9 A;  1PWQ A;  1SAT A;  1D8F A;  1XAX A;  1K7I A;  1JIW P;  3LJG A;  2DDY A;  4PKW A;  2RJP A;  1K7Q A;  4XBH A;  1EAK A;  4GWM A;  3LE9 A;  2ERO A;  4L7A A;  2XS3 A;  3L0V A;  1IAB A;  1XUC A;  2CLT A;  1BIW A;  2ERQ A;  1EUB A;  5D3C A;  2AYK A;  456C A;  3KWV C;  5BPA A;  2O36 A;  4FXY P;  1OMJ A;  2X3B A;  2OY2 A;  2O3E A;  1OO9 A;  3HY9 A;  1UMS A;  2YUF A;  1UMT A;  1ROS A;  3ZVS A;  4A3W A;  1ZP5 A;  1R1H A;  1FLS A;  3F17 A;  2JT5 A; 
#chains in the Genus database with same CATH homology
 3LUM A;  2JSD A;  2DW0 A;  3TVC A;  5I12 A;  3VTG A;  1AKL A;  1OM7 A;  1QJJ A;  2X7M A;  4GUY A;  3LIK A;  1A85 A;  5L79 A;  1UEA A;  4ILW D;  1R54 A;  3HBU P;  3EDZ A;  1SLN A;  3AYK A;  2OW9 A;  3LKA A;  1FM1 A;  5B5O A;  1OM6 A;  1PWV A;  2W15 A;  1PWW A;  2V4B A;  4GR8 A;  2MLR A;  1IAD A;  1MNC A;  4WF6 A;  3G42 A;  2MZI A;  3HYG A;  1SRP A;  1EB6 A;  3HDA P;  1BKC I;  4PKU A;  2PJT A;  1Y93 A;  1MMB A;  1Y0V A;  1XFU A;  1KAP P;  1IAA A;  1BQO A;  5B5P A;  1JAP A;  1JIZ A;  5CUH A;  1O0T A;  2K9C A;  1JAQ A;  1BKC A;  1BUV M;  3LQB A;  1JAN A;  4FU4 A;  1AYK A;  1G05 A;  4H84 A;  1HFC A;  1O0Q A;  1XUR A;  4PKT A;  1ZXC A;  1G12 A;  2FV9 A;  1ZS0 A;  3KMC A;  4L63 A;  1XFX A;  1GE5 A;  1KUH A;  1QIB A;  2JT6 A;  2MZE A;  2X3A A;  830C A;  3NX7 A;  4XM8 A;  5D1T A;  3HDB A;  3EDI A;  3L0T A;  1C7K A;  4PKV A;  4H82 A;  2YB9 A;  4WKI A;  2J0T A;  1HY7 A;  1JAO A;  2MLS A;  3LIL A;  1UTZ A;  1GO8 P;  4IUW A;  4DPE A;  1G49 A;  3KEJ A;  3AIG A;  1I73 A;  3N2V A;  2SRT A;  1GE6 A;  3N2U A;  1D7X A;  1SLM A;  2W0D A;  2OI0 A;  5BOY A;  3V96 B;  3DPE A;  3LIR A;  2OW1 A;  2CKI A;  2OY4 A;  1QJI A;  1GKC A;  5D7W A;  1BSW A;  3BA0 A;  1YQY A;  1D5J A;  2Z2D A;  3K7N A;  4AIG A;  5H8X A;  3O64 A;  5L7F A;  4XM7 A;  2OVX A;  3USN A;  4ON1 A;  4J4M A;  3DSL A;  1ZVX A;  1I76 A;  2RJQ A;  1KUK A;  4ZR5 A;  3TT4 A;  2DW1 A;  2USN A;  4JA1 A;  2OXU A;  1CGF A;  2YIG A;  1JKY A;  4WKE A;  2Y6C A;  3AYU A;  4JIJ A;  3HB2 P;  1XFZ A;  3KEC A;  4JP4 A;  4H30 A;  2QPJ A;  3EDH A;  2OXZ A;  4QKZ A;  3I7I A;  4G9L A;  5JMY A;  1MMP A;  3G5C A;  3OHO A;  4I35 A;  1ND1 A;  2N8R A;  2E3X A;  3TS4 A;  1HFS A;  1XFW A;  1YCM A;  1Z3J A;  966C A;  4PKQ A;  1PWP A;  3GBO A;  1BZS A;  1QIA A;  2KRJ A;  3F19 A;  4GQL A;  2WO9 A;  4CTH A;  3LK8 A;  3KME A;  3HBV P;  4WK7 A;  1BKC E;  2K2G A;  4GWN A;  3WV1 A;  1KUI A;  3B2Z A;  3B8Z A;  4AYK A;  5I0L A;  1H71 P;  1BQQ M;  1C8T A;  5I3M A;  2TCL A;  1BM6 A;  2OW2 A;  4L6T A;  3LUN A;  3E8R A;  4DD8 A;  1G4K A;  1RMZ A;  1GE7 A;  3VI1 A;  1SU3 A;  1CGL A;  2POJ A;  2WOA A;  4H3X A;  4GR0 A;  4IJO A;  2D1N A;  4XM6 A;  1UTT A;  4PKR A;  4AXQ A;  2FV5 A;  3EDG A;  3LEA A;  3CKI A;  3I7G A;  1JH1 A;  1YP1 A;  3F1A A;  1YOU A;  4H49 A;  4XCT A;  3SHI A;  2DDF A;  2OVZ A;  1MMQ A;  1R55 A;  4DF9 A;  2OZR A;  5D1U A;  4GF1 A;  1R1I A;  1ZXV A;  3ZUK A;  1WNI A;  3EHY A;  3EWJ A;  1DMT A;  5LAB A;  5I43 A;  2I47 A;  5D2B A;  3RTS A;  3LJT A;  1OS2 A;  3OHL A;  1J7N A;  1R1J A;  3Q2G A;  4FXQ A;  2X3C A;  3P1V A;  4Q1L A;  4L19 A;  3UVC A;  2E2D A;  1B3D A;  4FVL A;  1KUF A;  1G9K A;  1KUG A;  4HX3 A;  1Q3A A;  4AUO A;  3U1R A;  4H76 A;  1GO7 P;  1RM8 A;  3K7L A;  3F18 A;  1D8M A;  5D1S A;  3TSK A;  4GR3 A;  4A7B A;  1IAE A;  1Y8J A;  4JPA A;  4H1Q A;  3KEK A;  5BOT A;  1C3I A;  1CXV A;  4DV8 A;  3DL1 A;  2J83 A;  1AST A;  1B8Y A;  1ATL A;  1HV5 A;  1HTD A;  3DTI A;  1CIZ A;  3DTE A;  3MA2 A;  2OXW A;  1SMP A;  3DTK A;  1DTH A;  3WV3 A;  5I2Z A;  2OW0 A;  2W12 A;  4G0D A;  1CGE A;  4H2E A;  3WV2 A;  1MMR A;  1CAQ A;  3KHI A;  5I4O A;  4R3V A;  4WZV A;  3KRY A;  1CQR A;  3DNG A;  3O2X A;  4EFS A;  3ZXH A;  3ELM A;  2W13 A;  2ERP A;  1S4B P;  5CZM A;  1XFY A;  5CXA A;  1XUD A;  4I03 A;  3P24 A;  1IAG A;  1HOV A;  1ZTQ A;  3RTT A;  1K7G A;  1GXD A;  2AIG P;  3LMC A;  3DPF A;  1I1I P;  2MZH A;  4HMA A;  3F16 A;  2XS4 A;  1AF0 A;  1BUD A;  2W14 A;  1IAC A;  1FBL A;  1GKD A;  2Y6D A;  1XFV A;  3LJZ A;  3F15 A;  1PWU A;  1OS9 A;  1QUA A;  2HU6 A;  2JIH A;  1QIC A;  2D1O A;  3Q2H A;  3LGP A;  2WO8 A;  1A86 A;  1KBC A;  1USN A;  2L0R A;  4PKS A;  1JK3 A;  3LQ0 A;  3B92 A;  3DWB A;  1L6J A;  1CK7 A;  2A8H A;  1OM8 A;  2DW2 A;  3HY7 A;  2JNP A;  4IN9 A;  3EHX A;  4JQG A;  1JJ9 A;  1PWQ A;  1SAT A;  1D8F A;  1K7I A;  1JIW P;  3LJG A;  2DDY A;  4PKW A;  2RJP A;  1K7Q A;  4XBH A;  1EAK A;  4GWM A;  3LE9 A;  2ERO A;  4L7A A;  2XS3 A;  3L0V A;  1IAB A;  1XUC A;  2CLT A;  1BIW A;  2ERQ A;  1EUB A;  5D3C A;  2AYK A;  456C A;  3KWV C;  5BPA A;  2O36 A;  4FXY P;  1OMJ A;  2X3B A;  2OY2 A;  2O3E A;  1OO9 A;  3HY9 A;  1UMS A;  2YUF A;  1UMT A;  1ROS A;  3ZVS A;  4A3W A;  1ZP5 A;  1R1H A;  1FLS A;  3F17 A;  2JT5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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