3KG6A

Dehydratase domain from curf module of curacin polyketide synthase
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
283
structure length
274
Chain Sequence
NAHPLLGEKINLAGIEDQHRFQSYIGAESPGYLNHHQVFGKVLFPSTGYLEIAASAGKSLFTSQEQVVVSDVDILQSLVIPETEIKTVQTVVSFAENNSYKFEIFSPSPQWVLHAQGKIYTEPTRNSQAKIDLEKYQAECSQAIEIEEHYREYRSKGIDYGSSFQGIKQLWKGQGKALGEMAFPEELTAQLADYQLHPALLDAAFQIVSYAIPETDKIYLPVGVEKFKLYRQTISQVWAIAEIRQTNLTANIFLVDNQGTVLVELEGLRVKVTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway.
pubmed doi rcsb
molecule tags Lyase
source organism Lyngbya majuscula
molecule keywords CurF
total genus 70
structure length 274
sequence length 283
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.61: Transferred entry: 4.2.1.59.
pdb deposition date 2009-10-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 3kg6A00
4OOCA 5KKUA 3KG9A 3HRRA 4LN9A 3EL6A 3KG7A 2VZ9A 3KG6A 5E1VA 5BP3A 4KC5A 3HRQA 4U3VA 2VZ8A 5BP2A
chains in the Genus database with same CATH superfamily
4RLTA 1Q4TA 2PZHA 2F3XA 4FFUA 3CJYA 4B0IA 3R35A 4HZOA 3ED0A 4K4BA 5SZZA 1VH9A 3TEAA 4A0YA 2O6BA 3KUVA 5BYUA 1IQ6A 1OHFA 3B7JA 3F1TA 2O6UA 3D6LA 1C8UA 3EL6A 5SZVA 5T02A 4ZV3A 3HMJG 4QFWA 3E29A 3KX8A 5BP2A 1VI8A 4I82A 4K02A 5BUWA 5BUYA 3R3BA 2QQPA 4K49A 5EP5A 2F0XA 3R34A 4AE8A 3E8PA 3LBEA 3IR3A 3HRQA 3LZ7A 3HM0A 2PIMA 2UV8G 4I83A 1SH8A 4M20A 4WNBB 1J1YA 1PSUA 4QDBA 3U0AA 5EGLA 1LO7A 3KVZA 3B7KA 2HX5A 2GF6A 2PFCA 4I4JA 3CF9A 2H4UA 4R9ZA 2EGIA 5HZ4A 3R3FA 4W78B 1NJKA 3ZH7B 1Q4SA 2EGRA 3SPSA 4K4AA 4E3EA 4MOCA 3DP3A 3P2RA 3AZ9A 4ZRFA 2EGJA 4MOBA 2W3XA 1LO9A 5DIOA 5T06A 3KVIA 5HWFA 1VH5A 4RLJB 4XY6A 3S6PA 4XY5A 4NCPA 4B0BA 2B6EA 4K00A 1YLIA 2OIWA 1BVQA 3KV8A 5E1VA 2F41A 4CL6A 3ZH6A 4MZQA 2OWNA 3R32A 5HMBA 3Q62A 2B3MA 3KG8A 3FRNA 3KV7A 3B18A 1Z6BA 2HBOA 3LBBA 4GAKA 1SBKA 3KG7A 3LMBA 3KW1A 4YBVA 5T07A 1Q4UA 1ZHGA 4KC5A 1YOCA 3ZH5A 3DP0A 4A12A 5SZUA 3KUWA 3R3AA 5DM5A 3HDUA 2V1OA 3OMLA 3P2QA 2GLPA 3DOZA 3BBJA 3RD7A 5BP3A 1WLVA 4QD8A 4RMMA 3P3IA 4WNBA 2C2IA 3KG9A 4RLUB 4RV2B 5HMCA 1U1ZA 3DOYA 4K4CA 2OAFA 4A0ZA 2FS2A 2FUJA 3P2SA 4OOBA 4RLTB 4RLUA 3R37A 4RV2A 3LW3A 2O6TA 1TBUA 2EISA 4W78A 3ZH7A 5BUXA 1VPMA 2OKIA 1WLUA 1WN3A 4I45A 4RLWB 2HLJA 3LWGA 1LO8A 1T82A 3KVUA 4U3VA 2VZ8A 4ZRBA 3WEWA 2QWZA 4ORDA 3CF8A 5CPGA 4RLJA 2Q78A 3R3DA 4RLWA 2ESSA 4B0CA 1MKBA 4R4UA 3RQBA 2VKZG 4ZW0A 2CWZA 5KL9A 3AZBA 2CYEA 4ZJBA 5EO2A 4B0JA 5HD6A 1Y7UA 3EXZA 3S4KA 3DP2A 3BJKA 2NUJA 3E1EA 1WM6A 4B8UA 3R3CA 3DKZA 2GLVA 3KH8A 4AE7A 4HZNA 1S9CA 2GVHA 4KEHA 5SZYA 2XEMA 2CY9A 5KKUA 3AZAA 4LN9A 4MTUA 5EO4A 3KX7A 4K4DA 4IENA 5EGJA 1MKAA 3AZ8A 4A0XA 4OOCA 5EGKA 1PN4A 2DSLA 2AV9A 4QD9A 3D04A 3DP1A 2QQ2A 3R87A 1SC0A 2GLLA 4QDAA 4GAHA 3ESIA 3CK1A 2OV9A 3P3FA 3F5OA 4H4GA 1PN2A 2GLMA 3D6XA 2OKHA 3GEKA 3R36A 1Q6WA 2Q2BA 5F6RA 1IXLA 2BI0A 3HRRA 2PRXA 3KHPA 1S5UA 3K67A 2VZ9A 3NWZA 1Z54A 2O5UA 3KG6A 3QY3A 4QD7A 2XFLA 3QOOA 4FQ9A 4HZPA 1ZKIA 3BNVA
chains in the Genus database with same CATH topology
5KKUA 3KG9A 3ZH7B 4LN9A 3CJYA 1OHFA 3ZH7A 4OOCA 3S6PA 3EL6A 5E1VA 3HMJG 4QFWA 3ZH6A 4U3VA 2VZ8A 5BP2A 3KG8A 3FRNA 3RD7A 2QQPA 3B18A 3KG7A 4R4UA 4KC5A 3HRQA 3RQBA 3ZH5A 2VKZG 2UV8G 3HRRA 2VZ9A 3U0AA 3KG6A 5BP3A 3BBJA 2PFCA 4R9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OOC A;  5KKU A;  3KG9 A;  3HRR A;  4LN9 A;  3EL6 A;  3KG7 A;  2VZ9 A;  3KG6 A;  5E1V A;  5BP3 A;  4KC5 A;  3HRQ A;  4U3V A;  2VZ8 A;  5BP2 A; 
#chains in the Genus database with same CATH topology
 4RLT A;  1Q4T A;  2PZH A;  2F3X A;  4FFU A;  3CJY A;  4B0I A;  3R35 A;  4HZO A;  3ED0 A;  4K4B A;  5SZZ A;  1VH9 A;  3TEA A;  4A0Y A;  2O6B A;  3KUV A;  5BYU A;  1IQ6 A;  1OHF A;  3B7J A;  3F1T A;  2O6U A;  3D6L A;  1C8U A;  3EL6 A;  5SZV A;  5T02 A;  4ZV3 A;  3HMJ G;  4QFW A;  3E29 A;  3KX8 A;  5BP2 A;  1VI8 A;  4I82 A;  4K02 A;  5BUW A;  5BUY A;  3R3B A;  2QQP A;  4K49 A;  5EP5 A;  2F0X A;  3R34 A;  4AE8 A;  3E8P A;  3LBE A;  3IR3 A;  3HRQ A;  3LZ7 A;  3HM0 A;  2PIM A;  2UV8 G;  4I83 A;  1SH8 A;  4M20 A;  4WNB B;  1J1Y A;  1PSU A;  4QDB A;  3U0A A;  5EGL A;  1LO7 A;  3KVZ A;  3B7K A;  2HX5 A;  2GF6 A;  2PFC A;  4I4J A;  3CF9 A;  2H4U A;  4R9Z A;  2EGI A;  5HZ4 A;  3R3F A;  4W78 B;  1NJK A;  3ZH7 B;  1Q4S A;  2EGR A;  3SPS A;  4K4A A;  4E3E A;  4MOC A;  3DP3 A;  3P2R A;  3AZ9 A;  4ZRF A;  2EGJ A;  4MOB A;  2W3X A;  1LO9 A;  5DIO A;  5T06 A;  3KVI A;  5HWF A;  1VH5 A;  4RLJ B;  4XY6 A;  3S6P A;  4XY5 A;  4NCP A;  4B0B A;  2B6E A;  4K00 A;  1YLI A;  2OIW A;  1BVQ A;  3KV8 A;  5E1V A;  2F41 A;  4CL6 A;  3ZH6 A;  4MZQ A;  2OWN A;  3R32 A;  5HMB A;  3Q62 A;  2B3M A;  3KG8 A;  3FRN A;  3KV7 A;  3B18 A;  1Z6B A;  2HBO A;  3LBB A;  4GAK A;  1SBK A;  3KG7 A;  3LMB A;  3KW1 A;  4YBV A;  5T07 A;  1Q4U A;  1ZHG A;  4KC5 A;  1YOC A;  3ZH5 A;  3DP0 A;  4A12 A;  5SZU A;  3KUW A;  3R3A A;  5DM5 A;  3HDU A;  2V1O A;  3OML A;  3P2Q A;  2GLP A;  3DOZ A;  3BBJ A;  3RD7 A;  5BP3 A;  1WLV A;  4QD8 A;  4RMM A;  3P3I A;  4WNB A;  2C2I A;  3KG9 A;  4RLU B;  4RV2 B;  5HMC A;  1U1Z A;  3DOY A;  4K4C A;  2OAF A;  4A0Z A;  2FS2 A;  2FUJ A;  3P2S A;  4OOB A;  4RLT B;  4RLU A;  3R37 A;  4RV2 A;  3LW3 A;  2O6T A;  1TBU A;  2EIS A;  4W78 A;  3ZH7 A;  5BUX A;  1VPM A;  2OKI A;  1WLU A;  1WN3 A;  4I45 A;  4RLW B;  2HLJ A;  3LWG A;  1LO8 A;  1T82 A;  3KVU A;  4U3V A;  2VZ8 A;  4ZRB A;  3WEW A;  2QWZ A;  4ORD A;  3CF8 A;  5CPG A;  4RLJ A;  2Q78 A;  3R3D A;  4RLW A;  2ESS A;  4B0C A;  1MKB A;  4R4U A;  3RQB A;  2VKZ G;  4ZW0 A;  2CWZ A;  5KL9 A;  3AZB A;  2CYE A;  4ZJB A;  5EO2 A;  4B0J A;  5HD6 A;  1Y7U A;  3EXZ A;  3S4K A;  3DP2 A;  3BJK A;  2NUJ A;  3E1E A;  1WM6 A;  4B8U A;  3R3C A;  3DKZ A;  2GLV A;  3KH8 A;  4AE7 A;  4HZN A;  1S9C A;  2GVH A;  4KEH A;  5SZY A;  2XEM A;  2CY9 A;  5KKU A;  3AZA A;  4LN9 A;  4MTU A;  5EO4 A;  3KX7 A;  4K4D A;  4IEN A;  5EGJ A;  1MKA A;  3AZ8 A;  4A0X A;  4OOC A;  5EGK A;  1PN4 A;  2DSL A;  2AV9 A;  4QD9 A;  3D04 A;  3DP1 A;  2QQ2 A;  3R87 A;  1SC0 A;  2GLL A;  4QDA A;  4GAH A;  3ESI A;  3CK1 A;  2OV9 A;  3P3F A;  3F5O A;  4H4G A;  1PN2 A;  2GLM A;  3D6X A;  2OKH A;  3GEK A;  3R36 A;  1Q6W A;  2Q2B A;  5F6R A;  1IXL A;  2BI0 A;  3HRR A;  2PRX A;  3KHP A;  1S5U A;  3K67 A;  2VZ9 A;  3NWZ A;  1Z54 A;  2O5U A;  3KG6 A;  3QY3 A;  4QD7 A;  2XFL A;  3QOO A;  4FQ9 A;  4HZP A;  1ZKI A;  3BNV A; 
#chains in the Genus database with same CATH homology
 5KKU A;  3KG9 A;  3ZH7 B;  4LN9 A;  3CJY A;  1OHF A;  3ZH7 A;  4OOC A;  3S6P A;  3EL6 A;  5E1V A;  3HMJ G;  4QFW A;  3ZH6 A;  4U3V A;  2VZ8 A;  5BP2 A;  3KG8 A;  3FRN A;  3RD7 A;  2QQP A;  3B18 A;  3KG7 A;  4R4U A;  4KC5 A;  3HRQ A;  3RQB A;  3ZH5 A;  2VKZ G;  2UV8 G;  3HRR A;  2VZ9 A;  3U0A A;  3KG6 A;  5BP3 A;  3BBJ A;  2PFC A;  4R9Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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