3KG7A

Dehydratase domain from curh module of curacin polyketide synthase
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
286
structure length
286
Chain Sequence
VHRLLGNKLELASTGQTIYHQDINLNNHPWIGDHRVYDTPVIPGVSYIAMTLAAVGVPAAVEDINFQQPLFLAESNTTRETQLMLHTADNVGKQFVEVFSRDGAKQEEWQQHASMSVSENPPPPPTLSVDIPALCEQLRPLDTDTLTEIYASISLVYGPMLQAVRQAWIGEETSLLEIEVPKALAFQLAGEPIHPVLIDACTRLTPDLFDFSSDSGVFWAPWRVKEMTLSHPTPSRFYAYVEEPSRVNEQLQTRSYDIQLLDETGQAFGRINGFTVKRAPSQLFLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway.
pubmed doi rcsb
molecule tags Lyase
source organism Lyngbya majuscula
molecule keywords CurH
total genus 59
structure length 286
sequence length 286
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.61: Transferred entry: 4.2.1.59.
pdb deposition date 2009-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14765 PS-DH Polyketide synthase dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 3kg7A00
4LN9A 4OOCA 5KKUA 5E1VA 3HRRA 5BP2A 3KG7A 3KG9A 2VZ9A 3HRQA 5BP3A 4U3VA 4KC5A 3KG6A 2VZ8A 3EL6A
chains in the Genus database with same CATH superfamily
1IXLA 3KW1A 4ORDA 2OWNA 2GLLA 2HBOA 2O5UA 1U1ZA 3LBEA 4RLUA 4RV2B 4E3EA 3DOYA 1Q4TA 3ED0A 2Q78A 4RLUB 2AV9A 4A0ZA 2XEMA 4ZW0A 1S9CA 1C8UA 4ZV3A 1LO9A 1ZHGA 2EGRA 1MKBA 3DP2A 3HDUA 4K4DA 4YBVA 2OIWA 1LO7A 2OKIA 4I45A 1Y7UA 3WEWA 3DOZA 1VH9A 3ZH5A 2GLMA 4ZRFA 5BUWA 3R87A 3ESIA 4K4AA 4I83A 2H4UA 3LBBA 3R3BA 2BI0A 3HM0A 2B3MA 3Q62A 4XY6A 4B0CA 1YOCA 2W3XA 3AZBA 4I4JA 3HMJG 4OOCA 2OKHA 2UV8G 3R3DA 4WNBB 3TEAA 3RQBA 5BP2A 4B0JA 2PZHA 4GAKA 1NJKA 3LWGA 3R34A 4K4CA 2V1OA 4RLJA 3E29A 1TBUA 5EGLA 5EO4A 3R37A 4K00A 4W78B 1WM6A 2GLPA 5EGKA 3B7JA 3KVZA 3ZH7A 4AE7A 2NUJA 4MTUA 4RLTB 5BP3A 2OV9A 3BBJA 3KG8A 1ZKIA 3AZ8A 2F41A 3F1TA 4I82A 3K67A 5BUXA 3KVIA 4U3VA 5BUYA 4A12A 3AZ9A 3BNVA 4R4UA 3B18A 3P3FA 3LZ7A 1Z6BA 3KH8A 4H4GA 4FFUA 5F6RA 3IR3A 1VH5A 3KUVA 4KEHA 4MOCA 4QD9A 4WNBA 4ZJBA 4K02A 3E8PA 4LN9A 4B0IA 5HZ4A 3FRNA 3HRRA 3KV7A 4HZNA 3KVUA 3HRQA 3LMBA 4HZPA 4NCPA 1MKAA 4ZRBA 4W78A 3E1EA 5T07A 3D04A 3NWZA 2Q2BA 3R32A 4RV2A 3F5OA 4B8UA 2QQPA 4A0YA 3R3CA 4HZOA 2QQ2A 2FUJA 2CYEA 2PRXA 2B6EA 2EGJA 2HLJA 2O6BA 2PFCA 3AZAA 3DP0A 3KG6A 2HX5A 3KX7A 5SZVA 3SPSA 5BYUA 3R35A 5HMBA 5EGJA 4CL6A 1VI8A 1VPMA 3KG9A 3P2RA 4M20A 3OMLA 2O6UA 4OOBA 5KL9A 2EGIA 2O6TA 3DKZA 3EXZA 1Q4SA 1YLIA 2CWZA 4K49A 3D6LA 4FQ9A 1Q6WA 5HD6A 2CY9A 3DP1A 3KG7A 3KHPA 1PSUA 1SBKA 2VZ9A 5DIOA 4QD7A 1OHFA 4A0XA 4AE8A 3U0AA 3QOOA 4QFWA 1S5UA 3CK1A 4QDAA 4RLWB 5EP5A 3B7KA 2QWZA 3KUWA 1J1YA 1IQ6A 5SZZA 4MOBA 4GAHA 3ZH6A 4MZQA 3LW3A 5SZYA 4RLJB 1Z54A 3S4KA 2OAFA 5KKUA 4IENA 3KX8A 3QY3A 2GVHA 4RLTA 3BJKA 4K4BA 1Q4UA 2C2IA 1WN3A 4KC5A 3RD7A 1BVQA 3ZH7B 4B0BA 4QD8A 2DSLA 2GLVA 3D6XA 2XFLA 3CF9A 2GF6A 3R3AA 3DP3A 4QDBA 1LO8A 1SC0A 3CJYA 5CPGA 3P2QA 2VZ8A 2FS2A 3EL6A 5EO2A 1T82A 3P2SA 2VKZG 5E1VA 1WLUA 5HMCA 2ESSA 3R3FA 3S6PA 4R9ZA 5DM5A 2EISA 1PN4A 4RLWA 4XY5A 2F0XA 3CF8A 3R36A 5T02A 3P3IA 1WLVA 2PIMA 3GEKA 5SZUA 3KV8A 1PN2A 2F3XA 5T06A 4RMMA 5HWFA 1SH8A
chains in the Genus database with same CATH topology
5KKUA 3ZH7A 4KC5A 3U0AA 3KG6A 2QQPA 2PFCA 3RD7A 3ZH7B 3BBJA 3KG8A 3KG9A 4U3VA 3CJYA 2VZ8A 3ZH5A 3EL6A 4R4UA 3B18A 2VKZG 5E1VA 3KG7A 2VZ9A 3S6PA 4R9ZA 1OHFA 4LN9A 4QFWA 3HMJG 3FRNA 4OOCA 3HRRA 2UV8G 5BP2A 3HRQA 3RQBA 5BP3A 3ZH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LN9 A;  4OOC A;  5KKU A;  5E1V A;  3HRR A;  5BP2 A;  3KG7 A;  3KG9 A;  2VZ9 A;  3HRQ A;  5BP3 A;  4U3V A;  4KC5 A;  3KG6 A;  2VZ8 A;  3EL6 A; 
#chains in the Genus database with same CATH topology
 1IXL A;  3KW1 A;  4ORD A;  2OWN A;  2GLL A;  2HBO A;  2O5U A;  1U1Z A;  3LBE A;  4RLU A;  4RV2 B;  4E3E A;  3DOY A;  1Q4T A;  3ED0 A;  2Q78 A;  4RLU B;  2AV9 A;  4A0Z A;  2XEM A;  4ZW0 A;  1S9C A;  1C8U A;  4ZV3 A;  1LO9 A;  1ZHG A;  2EGR A;  1MKB A;  3DP2 A;  3HDU A;  4K4D A;  4YBV A;  2OIW A;  1LO7 A;  2OKI A;  4I45 A;  1Y7U A;  3WEW A;  3DOZ A;  1VH9 A;  3ZH5 A;  2GLM A;  4ZRF A;  5BUW A;  3R87 A;  3ESI A;  4K4A A;  4I83 A;  2H4U A;  3LBB A;  3R3B A;  2BI0 A;  3HM0 A;  2B3M A;  3Q62 A;  4XY6 A;  4B0C A;  1YOC A;  2W3X A;  3AZB A;  4I4J A;  3HMJ G;  4OOC A;  2OKH A;  2UV8 G;  3R3D A;  4WNB B;  3TEA A;  3RQB A;  5BP2 A;  4B0J A;  2PZH A;  4GAK A;  1NJK A;  3LWG A;  3R34 A;  4K4C A;  2V1O A;  4RLJ A;  3E29 A;  1TBU A;  5EGL A;  5EO4 A;  3R37 A;  4K00 A;  4W78 B;  1WM6 A;  2GLP A;  5EGK A;  3B7J A;  3KVZ A;  3ZH7 A;  4AE7 A;  2NUJ A;  4MTU A;  4RLT B;  5BP3 A;  2OV9 A;  3BBJ A;  3KG8 A;  1ZKI A;  3AZ8 A;  2F41 A;  3F1T A;  4I82 A;  3K67 A;  5BUX A;  3KVI A;  4U3V A;  5BUY A;  4A12 A;  3AZ9 A;  3BNV A;  4R4U A;  3B18 A;  3P3F A;  3LZ7 A;  1Z6B A;  3KH8 A;  4H4G A;  4FFU A;  5F6R A;  3IR3 A;  1VH5 A;  3KUV A;  4KEH A;  4MOC A;  4QD9 A;  4WNB A;  4ZJB A;  4K02 A;  3E8P A;  4LN9 A;  4B0I A;  5HZ4 A;  3FRN A;  3HRR A;  3KV7 A;  4HZN A;  3KVU A;  3HRQ A;  3LMB A;  4HZP A;  4NCP A;  1MKA A;  4ZRB A;  4W78 A;  3E1E A;  5T07 A;  3D04 A;  3NWZ A;  2Q2B A;  3R32 A;  4RV2 A;  3F5O A;  4B8U A;  2QQP A;  4A0Y A;  3R3C A;  4HZO A;  2QQ2 A;  2FUJ A;  2CYE A;  2PRX A;  2B6E A;  2EGJ A;  2HLJ A;  2O6B A;  2PFC A;  3AZA A;  3DP0 A;  3KG6 A;  2HX5 A;  3KX7 A;  5SZV A;  3SPS A;  5BYU A;  3R35 A;  5HMB A;  5EGJ A;  4CL6 A;  1VI8 A;  1VPM A;  3KG9 A;  3P2R A;  4M20 A;  3OML A;  2O6U A;  4OOB A;  5KL9 A;  2EGI A;  2O6T A;  3DKZ A;  3EXZ A;  1Q4S A;  1YLI A;  2CWZ A;  4K49 A;  3D6L A;  4FQ9 A;  1Q6W A;  5HD6 A;  2CY9 A;  3DP1 A;  3KG7 A;  3KHP A;  1PSU A;  1SBK A;  2VZ9 A;  5DIO A;  4QD7 A;  1OHF A;  4A0X A;  4AE8 A;  3U0A A;  3QOO A;  4QFW A;  1S5U A;  3CK1 A;  4QDA A;  4RLW B;  5EP5 A;  3B7K A;  2QWZ A;  3KUW A;  1J1Y A;  1IQ6 A;  5SZZ A;  4MOB A;  4GAH A;  3ZH6 A;  4MZQ A;  3LW3 A;  5SZY A;  4RLJ B;  1Z54 A;  3S4K A;  2OAF A;  5KKU A;  4IEN A;  3KX8 A;  3QY3 A;  2GVH A;  4RLT A;  3BJK A;  4K4B A;  1Q4U A;  2C2I A;  1WN3 A;  4KC5 A;  3RD7 A;  1BVQ A;  3ZH7 B;  4B0B A;  4QD8 A;  2DSL A;  2GLV A;  3D6X A;  2XFL A;  3CF9 A;  2GF6 A;  3R3A A;  3DP3 A;  4QDB A;  1LO8 A;  1SC0 A;  3CJY A;  5CPG A;  3P2Q A;  2VZ8 A;  2FS2 A;  3EL6 A;  5EO2 A;  1T82 A;  3P2S A;  2VKZ G;  5E1V A;  1WLU A;  5HMC A;  2ESS A;  3R3F A;  3S6P A;  4R9Z A;  5DM5 A;  2EIS A;  1PN4 A;  4RLW A;  4XY5 A;  2F0X A;  3CF8 A;  3R36 A;  5T02 A;  3P3I A;  1WLV A;  2PIM A;  3GEK A;  5SZU A;  3KV8 A;  1PN2 A;  2F3X A;  5T06 A;  4RMM A;  5HWF A;  1SH8 A; 
#chains in the Genus database with same CATH homology
 5KKU A;  3ZH7 A;  4KC5 A;  3U0A A;  3KG6 A;  2QQP A;  2PFC A;  3RD7 A;  3ZH7 B;  3BBJ A;  3KG8 A;  3KG9 A;  4U3V A;  3CJY A;  2VZ8 A;  3ZH5 A;  3EL6 A;  4R4U A;  3B18 A;  2VKZ G;  5E1V A;  3KG7 A;  2VZ9 A;  3S6P A;  4R9Z A;  1OHF A;  4LN9 A;  4QFW A;  3HMJ G;  3FRN A;  4OOC A;  3HRR A;  2UV8 G;  5BP2 A;  3HRQ A;  3RQB A;  5BP3 A;  3ZH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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