3KMCA

Crystal structure of catalytic domain of tace with tartrate-based inhibitor
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
255
Chain Sequence
PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPNSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TNF-alpha-converting enzyme
publication title The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 81
structure length 255
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kmcA00
5D1TA 1RM8A 3HY9A 3LIRA 1HTDA 1EB6A 1ZXCA 1J7NA 1SU3A 3USNA 1GKCA 3N2VA 3HYGA 1XUCA 4PKSA 1ZS0A 1JIWP 3KRYA 3V96B 1K7QA 4PKQA 1Q3AA 2O3EA 5I4OA 1UMSA 2HU6A 3RTSA 3KEKA 3HDAP 1C3IA 1KUGA 4FXQA 4HMAA 2W13A 4ILWD 1SLNA 2JNPA 4XM8A 1UTZA 1C8TA 1ZTQA 1OM6A 4Q1LA 5D1UA 1XUDA 4JP4A 2WOAA 1XFWA 2DDFA 1G4KA 1ROSA 3LJTA 3F19A 2YIGA 2ERQA 2OW1A 4JIJA 1KBCA 1YQYA 1BSWA 2OY2A 4GWMA 5BPAA 5I2ZA 5D7WA 3ZUKA 1UEAA 1MNCA 4H76A 1D7XA 1QJIA 1SLMA 3K7LA 2OXZA 2D1OA 2DW1A 1BQQM 1BKCA 1B8YA 1SMPA 830CA 3EHXA 4GR3A 1BKCE 3O2XA 1OMJA 1YP1A 1XFYA 2OXUA 5B5OA 1UMTA 2WO9A 3TVCA 3EWJA 1CGEA 1GKDA 4FXYP 1FLSA 3DL1A 2JT6A 4H1QA 4EFSA 1CIZA 1SATA 1K7GA 3UVCA 2OI0A 4I35A 1FM1A 2N8RA 1BZSA 3U1RA 1I73A 1MMRA 1XURA 2OW0A 3F1AA 1XFVA 1SRPA 4FVLA 1KUKA 4GF1A 4DV8A 3DWBA 4H2EA 4XBHA 2YB9A 1BKCI 5CZMA 5I0LA 3EHYA 1BM6A 3EDHA 3KECA 1IACA 2AIGP 3ZXHA 1QICA 2X7MA 3B8ZA 1ZVXA 3K7NA 3DPEA 3HB2P 1C7KA 2CLTA 1JANA 3F18A 4GQLA 4H82A 2SRTA 4XM7A 5BOYA 5L7FA 3HBUP 4WKIA 3O64A 2Y6CA 3P1VA 3LE9A 3WV1A 4GR8A 1R1HA 2W0DA 1ATLA 1AKLA 1JAOA 1QUAA 3EDIA 4XM6A 1HOVA 3CKIA 3KMEA 1CGFA 2A8HA 1ZP5A 1R1JA 2Y6DA 3WV3A 1KAPP 3Q2GA 4WKEA 1IAAA 4AYKA 1HFSA 3EDGA 4H49A 2V4BA 2QPJA 1ND1A 2OY4A 3LMCA 2MZIA 3N2UA 1CXVA 3KWVC 1I1IP 3AYUA 2E2DA 2E3XA 3LK8A 1KUFA 1JJ9A 2X3CA 3LIKA 4PKWA 4L6TA 4AIGA 1H71P 2DDYA 1GE7A 4GWNA 4QKZA 3LQ0A 3NX7A 1Y8JA 4R3VA 1KUIA 5D1SA 4L19A 5B5PA 1Y0VA 4PKTA 2XS3A 3LJZA 2DW2A 2JT5A 1IADA 1IAEA 3AYKA 4DD8A 3P24A 3LILA 1ASTA 1AF0A 3DNGA 5L79A 2PJTA 3KEJA 1O0TA 4PKRA 2J83A 1D8MA 3B2ZA 966CA 1EUBA 1G05A 1BQOA 4H84A 1PWWA 1Y93A 1JAPA 1S4BP 3OHLA 1D8FA 4G9LA 2AYKA 4ON1A 3VI1A 3LJGA 3TT4A 3Q2HA 3B92A 1XFZA 3BA0A 4J4MA 2TCLA 2KRJA 2OW2A 1CGLA 1K7IA 2W12A 3F17A 3F16A 1JK3A 5D2BA 4AUOA 1G49A 1XFUA 2EROA 2MLRA 1FBLA 3KHIA 4H3XA 456CA 2X3AA 2XS4A 3HDBA 4JQGA 1HFCA 4IUWA 1MMBA 1PWQA 1XFXA 3HY7A 4GR0A 1D5JA 1IAGA 3L0TA 4FU4A 2OVXA 3LEAA 5H8XA 4WZVA 1PWUA 1B3DA 3SHIA 1OM8A 1JIZA 2D1NA 1YCMA 4CTHA 2RJQA 4A3WA 1GE5A 4DF9A 1A85A 2W14A 1JH1A 4IJOA 3EDZA 1R54A 3OHOA 3RTTA 2OZRA 1OM7A 3LQBA 1BIWA 5JMYA 1Z3JA 3GBOA 4PKVA 2L0RA 1I76A 3MA2A 1CAQA 3WV2A 3AIGA 5I43A 3LUNA 1UTTA 1PWPA 1QIAA 4H30A 1BUDA 1MMPA 5BOTA 1CQRA 1GO7P 1GXDA 3KMCA 2J0TA 4ZR5A 5D3CA 1YOUA 2POJA 2Z2DA 3I7GA 3E8RA 5CXAA 1A86A 2RJPA 2OW9A 2CKIA 3L0VA 4I03A 1AYKA 2MLSA 3I7IA 2FV5A 2MZEA 1L6JA 1R1IA 4WK7A 3LGPA 5I3MA 5I12A 3TS4A 1OS9A 3LKAA 5LABA 3VTGA 1GO8P 1JKYA 4L63A 4GUYA 1EAKA 1GE6A 2JSDA 1MMQA 1DMTA 2JIHA 1QIBA 4WF6A 1KUHA 3LUMA 2WO8A 2OXWA 1HV5A 2O36A 2FV9A 1PWVA 4HX3A 3HBVP 4PKUA 1IABA 4JA1A 2OVZA 3ELMA 4IN9A 3TSKA 1DTHA 3F15A 1QJJA 2X3BA 3G5CA 2W15A 4AXQA 3DPFA 1JAQA 2MZHA 1HY7A 2K2GA 3G42A 1G9KA 1ZXVA 2K9CA 1O0QA 4G0DA 5CUHA 1RMZA 4DPEA 1CK7A 1WNIA 1USNA 2DW0A 1R55A 4XCTA 1G12A 1OO9A 1BUVM 4A7BA 1OS2A 2I47A 2USNA 3ZVSA 2ERPA 4JPAA 3DSLA
chains in the Genus database with same CATH superfamily
5D1TA 1RM8A 3HY9A 3LIRA 1HTDA 1EB6A 1ZXCA 1J7NA 1SU3A 3USNA 1GKCA 3N2VA 3HYGA 1XUCA 4PKSA 1ZS0A 1JIWP 3KRYA 3V96B 1K7QA 4PKQA 1Q3AA 2O3EA 5I4OA 1UMSA 2HU6A 3RTSA 1XAXA 3KEKA 3HDAP 1C3IA 1KUGA 1TVIA 4FXQA 4HMAA 2W13A 4ILWD 1SLNA 3DTIA 2JNPA 4XM8A 1UTZA 1C8TA 1ZTQA 1OM6A 4Q1LA 5D1UA 1XUDA 4JP4A 2WOAA 1XFWA 2DDFA 1G4KA 1ROSA 3LJTA 3F19A 2YIGA 2ERQA 2OW1A 4JIJA 1KBCA 1YQYA 1BSWA 2OY2A 4GWMA 5BPAA 5I2ZA 5D7WA 3ZUKA 1UEAA 1MNCA 4H76A 1D7XA 1QJIA 1SLMA 3K7LA 2OXZA 2D1OA 2DW1A 1BQQM 1BKCA 1B8YA 1SMPA 3DTKA 830CA 3EHXA 4GR3A 1BKCE 3O2XA 1OMJA 1YP1A 1XFYA 2OXUA 5B5OA 1UMTA 2WO9A 3TVCA 3EWJA 1CGEA 1GKDA 4FXYP 1FLSA 3DL1A 2JT6A 4H1QA 4EFSA 1CIZA 1SATA 1K7GA 3UVCA 2OI0A 4I35A 1FM1A 2N8RA 1BZSA 3U1RA 1I73A 1MMRA 1XURA 2OW0A 3F1AA 1XFVA 1SRPA 4FVLA 1KUKA 4GF1A 4DV8A 3DWBA 4H2EA 4XBHA 2YB9A 1BKCI 5CZMA 5I0LA 3EHYA 1BM6A 3EDHA 3KECA 1IACA 2AIGP 3ZXHA 1QICA 2X7MA 3B8ZA 1ZVXA 3K7NA 3DPEA 3HB2P 1C7KA 2CLTA 1JANA 3F18A 4GQLA 4H82A 2SRTA 4XM7A 5BOYA 5L7FA 3HBUP 4WKIA 3O64A 2Y6CA 3P1VA 3LE9A 3WV1A 4GR8A 1R1HA 2W0DA 1ATLA 1AKLA 1JAOA 1QUAA 3EDIA 4XM6A 1HOVA 3CKIA 3KMEA 1CGFA 2A8HA 1ZP5A 1R1JA 2Y6DA 3WV3A 1KAPP 3Q2GA 4WKEA 1IAAA 4AYKA 1HFSA 3EDGA 4H49A 2V4BA 2QPJA 1ND1A 2OY4A 3LMCA 2MZIA 3N2UA 1CXVA 3KWVC 1I1IP 3AYUA 2E2DA 2E3XA 3LK8A 1KUFA 1JJ9A 2X3CA 3LIKA 4PKWA 4L6TA 1XM5A 4AIGA 1H71P 3DTEA 2DDYA 1GE7A 4GWNA 4QKZA 3LQ0A 3NX7A 1Y8JA 4R3VA 1KUIA 5D1SA 4L19A 5B5PA 1Y0VA 4PKTA 2XS3A 3LJZA 2DW2A 2JT5A 1IADA 1IAEA 3AYKA 4DD8A 3P24A 4L7AA 3LILA 1ASTA 1AF0A 3DNGA 5L79A 2PJTA 3KEJA 1O0TA 4PKRA 2J83A 1D8MA 3B2ZA 966CA 1EUBA 1G05A 1BQOA 4H84A 1PWWA 1Y93A 1JAPA 1S4BP 3OHLA 1D8FA 4G9LA 2AYKA 4ON1A 3VI1A 3LJGA 3TT4A 3Q2HA 3B92A 1XFZA 3BA0A 4J4MA 2TCLA 2KRJA 2OW2A 1CGLA 1K7IA 2W12A 3F17A 3F16A 1JK3A 5D2BA 4AUOA 1G49A 1XFUA 2EROA 2MLRA 1FBLA 3KHIA 4H3XA 456CA 2X3AA 2XS4A 3HDBA 4JQGA 1HFCA 4IUWA 1MMBA 1PWQA 1XFXA 3HY7A 4GR0A 1D5JA 1IAGA 3L0TA 4FU4A 2OVXA 3LEAA 5H8XA 4WZVA 1PWUA 1B3DA 3SHIA 1OM8A 1JIZA 2D1NA 1YCMA 4CTHA 2RJQA 4A3WA 1GE5A 4DF9A 1A85A 2W14A 1JH1A 4IJOA 3EDZA 1R54A 3OHOA 3RTTA 2OZRA 1OM7A 3LQBA 1BIWA 5JMYA 1Z3JA 3GBOA 4PKVA 2L0RA 1I76A 3MA2A 1CAQA 3WV2A 3AIGA 5I43A 3LUNA 1UTTA 1PWPA 1QIAA 4H30A 1BUDA 1MMPA 5BOTA 1CQRA 1GO7P 1GXDA 3KMCA 2J0TA 4ZR5A 5D3CA 1YOUA 2POJA 2Z2DA 2YUFA 3I7GA 3E8RA 5CXAA 1A86A 2RJPA 2OW9A 2CKIA 3L0VA 4I03A 1AYKA 1OZ9A 2MLSA 3I7IA 2FV5A 2MZEA 1L6JA 1R1IA 4WK7A 3LGPA 5I3MA 5I12A 3TS4A 1OS9A 3LKAA 5LABA 3VTGA 1GO8P 1JKYA 4L63A 4GUYA 1EAKA 1GE6A 2JSDA 1MMQA 1DMTA 2JIHA 1QIBA 4WF6A 1KUHA 3LUMA 2WO8A 2OXWA 1HV5A 2O36A 2FV9A 1PWVA 4HX3A 3HBVP 4PKUA 1IABA 4JA1A 2OVZA 3ELMA 4IN9A 3TSKA 1DTHA 3F15A 1QJJA 2X3BA 3G5CA 2W15A 4AXQA 3DPFA 1JAQA 2MZHA 1HY7A 2K2GA 3G42A 1G9KA 1ZXVA 2K9CA 1O0QA 4G0DA 5CUHA 1RMZA 4DPEA 1CK7A 1WNIA 1USNA 2DW0A 1R55A 4XCTA 1G12A 1OO9A 1BUVM 4A7BA 1OS2A 2I47A 2USNA 3ZVSA 2ERPA 4JPAA 3DSLA
chains in the Genus database with same CATH topology
5D1TA 1RM8A 3HY9A 3LIRA 1HTDA 1EB6A 1ZXCA 1J7NA 1SU3A 3USNA 1GKCA 3N2VA 3HYGA 1XUCA 4PKSA 1ZS0A 1JIWP 3KRYA 3V96B 1K7QA 4PKQA 1Q3AA 2O3EA 5I4OA 1UMSA 2HU6A 3RTSA 3KEKA 3HDAP 1C3IA 1KUGA 4FXQA 4HMAA 2W13A 4ILWD 1SLNA 3DTIA 2JNPA 4XM8A 1UTZA 1C8TA 1ZTQA 1OM6A 4Q1LA 5D1UA 1XUDA 4JP4A 2WOAA 1XFWA 2DDFA 1G4KA 1ROSA 3LJTA 3F19A 2YIGA 2ERQA 2OW1A 4JIJA 1KBCA 1YQYA 1BSWA 2OY2A 4GWMA 5BPAA 5I2ZA 5D7WA 3ZUKA 1UEAA 1MNCA 4H76A 1D7XA 1QJIA 1SLMA 3K7LA 2OXZA 2D1OA 2DW1A 1BQQM 1BKCA 1B8YA 1SMPA 3DTKA 830CA 3EHXA 4GR3A 1BKCE 3O2XA 1OMJA 1YP1A 1XFYA 2OXUA 5B5OA 1UMTA 2WO9A 3TVCA 3EWJA 1CGEA 1GKDA 4FXYP 1FLSA 3DL1A 2JT6A 4H1QA 4EFSA 1CIZA 1SATA 1K7GA 3UVCA 2OI0A 4I35A 1FM1A 2N8RA 1BZSA 3U1RA 1I73A 1MMRA 1XURA 2OW0A 3F1AA 1XFVA 1SRPA 4FVLA 1KUKA 4GF1A 4DV8A 3DWBA 4H2EA 4XBHA 2YB9A 1BKCI 5CZMA 5I0LA 3EHYA 1BM6A 3EDHA 3KECA 1IACA 2AIGP 3ZXHA 1QICA 2X7MA 3B8ZA 1ZVXA 3K7NA 3DPEA 3HB2P 1C7KA 2CLTA 1JANA 3F18A 4GQLA 4H82A 2SRTA 4XM7A 5BOYA 5L7FA 3HBUP 4WKIA 3O64A 2Y6CA 3P1VA 3LE9A 3WV1A 4GR8A 1R1HA 2W0DA 1ATLA 1AKLA 1JAOA 1QUAA 3EDIA 4XM6A 1HOVA 3CKIA 3KMEA 1CGFA 2A8HA 1ZP5A 1R1JA 2Y6DA 3WV3A 1KAPP 3Q2GA 4WKEA 1IAAA 4AYKA 1HFSA 3EDGA 4H49A 2V4BA 2QPJA 1ND1A 2OY4A 3LMCA 2MZIA 3N2UA 1CXVA 3KWVC 1I1IP 3AYUA 2E2DA 2E3XA 3LK8A 1KUFA 1JJ9A 2X3CA 3LIKA 4PKWA 4L6TA 4AIGA 1H71P 3DTEA 2DDYA 1GE7A 4GWNA 4QKZA 3LQ0A 3NX7A 1Y8JA 4R3VA 1KUIA 5D1SA 4L19A 5B5PA 1Y0VA 4PKTA 2XS3A 3LJZA 2DW2A 2JT5A 1IADA 1IAEA 3AYKA 4DD8A 3P24A 4L7AA 3LILA 1ASTA 1AF0A 3DNGA 5L79A 2PJTA 3KEJA 1O0TA 4PKRA 2J83A 1D8MA 3B2ZA 966CA 1EUBA 1G05A 1BQOA 4H84A 1PWWA 1Y93A 1JAPA 1S4BP 3OHLA 1D8FA 4G9LA 2AYKA 4ON1A 3VI1A 3LJGA 3TT4A 3Q2HA 3B92A 1XFZA 3BA0A 4J4MA 2TCLA 2KRJA 2OW2A 1CGLA 1K7IA 2W12A 3F17A 3F16A 1JK3A 5D2BA 4AUOA 1G49A 1XFUA 2EROA 2MLRA 1FBLA 3KHIA 4H3XA 456CA 2X3AA 2XS4A 3HDBA 4JQGA 1HFCA 4IUWA 1MMBA 1PWQA 1XFXA 3HY7A 4GR0A 1D5JA 1IAGA 3L0TA 4FU4A 2OVXA 3LEAA 5H8XA 4WZVA 1PWUA 1B3DA 3SHIA 1OM8A 1JIZA 2D1NA 1YCMA 4CTHA 2RJQA 4A3WA 1GE5A 4DF9A 1A85A 2W14A 1JH1A 4IJOA 3EDZA 1R54A 3OHOA 3RTTA 2OZRA 1OM7A 3LQBA 1BIWA 5JMYA 1Z3JA 3GBOA 4PKVA 2L0RA 1I76A 3MA2A 1CAQA 3WV2A 3AIGA 5I43A 3LUNA 1UTTA 1PWPA 1QIAA 4H30A 1BUDA 1MMPA 5BOTA 1CQRA 1GO7P 1GXDA 3KMCA 2J0TA 4ZR5A 5D3CA 1YOUA 2POJA 2Z2DA 2YUFA 3I7GA 3E8RA 5CXAA 1A86A 2RJPA 2OW9A 2CKIA 3L0VA 4I03A 1AYKA 2MLSA 3I7IA 2FV5A 2MZEA 1L6JA 1R1IA 4WK7A 3LGPA 5I3MA 5I12A 3TS4A 1OS9A 3LKAA 5LABA 3VTGA 1GO8P 1JKYA 4L63A 4GUYA 1EAKA 1GE6A 2JSDA 1MMQA 1DMTA 2JIHA 1QIBA 4WF6A 1KUHA 3LUMA 2WO8A 2OXWA 1HV5A 2O36A 2FV9A 1PWVA 4HX3A 3HBVP 4PKUA 1IABA 4JA1A 2OVZA 3ELMA 4IN9A 3TSKA 1DTHA 3F15A 1QJJA 2X3BA 3G5CA 2W15A 4AXQA 3DPFA 1JAQA 2MZHA 1HY7A 2K2GA 3G42A 1G9KA 1ZXVA 2K9CA 1O0QA 4G0DA 5CUHA 1RMZA 4DPEA 1CK7A 1WNIA 1USNA 2DW0A 1R55A 4XCTA 1G12A 1OO9A 1BUVM 4A7BA 1OS2A 2I47A 2USNA 3ZVSA 2ERPA 4JPAA 3DSLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D1T A;  1RM8 A;  3HY9 A;  3LIR A;  1HTD A;  1EB6 A;  1ZXC A;  1J7N A;  1SU3 A;  3USN A;  1GKC A;  3N2V A;  3HYG A;  1XUC A;  4PKS A;  1ZS0 A;  1JIW P;  3KRY A;  3V96 B;  1K7Q A;  4PKQ A;  1Q3A A;  2O3E A;  5I4O A;  1UMS A;  2HU6 A;  3RTS A;  3KEK A;  3HDA P;  1C3I A;  1KUG A;  4FXQ A;  4HMA A;  2W13 A;  4ILW D;  1SLN A;  2JNP A;  4XM8 A;  1UTZ A;  1C8T A;  1ZTQ A;  1OM6 A;  4Q1L A;  5D1U A;  1XUD A;  4JP4 A;  2WOA A;  1XFW A;  2DDF A;  1G4K A;  1ROS A;  3LJT A;  3F19 A;  2YIG A;  2ERQ A;  2OW1 A;  4JIJ A;  1KBC A;  1YQY A;  1BSW A;  2OY2 A;  4GWM A;  5BPA A;  5I2Z A;  5D7W A;  3ZUK A;  1UEA A;  1MNC A;  4H76 A;  1D7X A;  1QJI A;  1SLM A;  3K7L A;  2OXZ A;  2D1O A;  2DW1 A;  1BQQ M;  1BKC A;  1B8Y A;  1SMP A;  830C A;  3EHX A;  4GR3 A;  1BKC E;  3O2X A;  1OMJ A;  1YP1 A;  1XFY A;  2OXU A;  5B5O A;  1UMT A;  2WO9 A;  3TVC A;  3EWJ A;  1CGE A;  1GKD A;  4FXY P;  1FLS A;  3DL1 A;  2JT6 A;  4H1Q A;  4EFS A;  1CIZ A;  1SAT A;  1K7G A;  3UVC A;  2OI0 A;  4I35 A;  1FM1 A;  2N8R A;  1BZS A;  3U1R A;  1I73 A;  1MMR A;  1XUR A;  2OW0 A;  3F1A A;  1XFV A;  1SRP A;  4FVL A;  1KUK A;  4GF1 A;  4DV8 A;  3DWB A;  4H2E A;  4XBH A;  2YB9 A;  1BKC I;  5CZM A;  5I0L A;  3EHY A;  1BM6 A;  3EDH A;  3KEC A;  1IAC A;  2AIG P;  3ZXH A;  1QIC A;  2X7M A;  3B8Z A;  1ZVX A;  3K7N A;  3DPE A;  3HB2 P;  1C7K A;  2CLT A;  1JAN A;  3F18 A;  4GQL A;  4H82 A;  2SRT A;  4XM7 A;  5BOY A;  5L7F A;  3HBU P;  4WKI A;  3O64 A;  2Y6C A;  3P1V A;  3LE9 A;  3WV1 A;  4GR8 A;  1R1H A;  2W0D A;  1ATL A;  1AKL A;  1JAO A;  1QUA A;  3EDI A;  4XM6 A;  1HOV A;  3CKI A;  3KME A;  1CGF A;  2A8H A;  1ZP5 A;  1R1J A;  2Y6D A;  3WV3 A;  1KAP P;  3Q2G A;  4WKE A;  1IAA A;  4AYK A;  1HFS A;  3EDG A;  4H49 A;  2V4B A;  2QPJ A;  1ND1 A;  2OY4 A;  3LMC A;  2MZI A;  3N2U A;  1CXV A;  3KWV C;  1I1I P;  3AYU A;  2E2D A;  2E3X A;  3LK8 A;  1KUF A;  1JJ9 A;  2X3C A;  3LIK A;  4PKW A;  4L6T A;  4AIG A;  1H71 P;  2DDY A;  1GE7 A;  4GWN A;  4QKZ A;  3LQ0 A;  3NX7 A;  1Y8J A;  4R3V A;  1KUI A;  5D1S A;  4L19 A;  5B5P A;  1Y0V A;  4PKT A;  2XS3 A;  3LJZ A;  2DW2 A;  2JT5 A;  1IAD A;  1IAE A;  3AYK A;  4DD8 A;  3P24 A;  3LIL A;  1AST A;  1AF0 A;  3DNG A;  5L79 A;  2PJT A;  3KEJ A;  1O0T A;  4PKR A;  2J83 A;  1D8M A;  3B2Z A;  966C A;  1EUB A;  1G05 A;  1BQO A;  4H84 A;  1PWW A;  1Y93 A;  1JAP A;  1S4B P;  3OHL A;  1D8F A;  4G9L A;  2AYK A;  4ON1 A;  3VI1 A;  3LJG A;  3TT4 A;  3Q2H A;  3B92 A;  1XFZ A;  3BA0 A;  4J4M A;  2TCL A;  2KRJ A;  2OW2 A;  1CGL A;  1K7I A;  2W12 A;  3F17 A;  3F16 A;  1JK3 A;  5D2B A;  4AUO A;  1G49 A;  1XFU A;  2ERO A;  2MLR A;  1FBL A;  3KHI A;  4H3X A;  456C A;  2X3A A;  2XS4 A;  3HDB A;  4JQG A;  1HFC A;  4IUW A;  1MMB A;  1PWQ A;  1XFX A;  3HY7 A;  4GR0 A;  1D5J A;  1IAG A;  3L0T A;  4FU4 A;  2OVX A;  3LEA A;  5H8X A;  4WZV A;  1PWU A;  1B3D A;  3SHI A;  1OM8 A;  1JIZ A;  2D1N A;  1YCM A;  4CTH A;  2RJQ A;  4A3W A;  1GE5 A;  4DF9 A;  1A85 A;  2W14 A;  1JH1 A;  4IJO A;  3EDZ A;  1R54 A;  3OHO A;  3RTT A;  2OZR A;  1OM7 A;  3LQB A;  1BIW A;  5JMY A;  1Z3J A;  3GBO A;  4PKV A;  2L0R A;  1I76 A;  3MA2 A;  1CAQ A;  3WV2 A;  3AIG A;  5I43 A;  3LUN A;  1UTT A;  1PWP A;  1QIA A;  4H30 A;  1BUD A;  1MMP A;  5BOT A;  1CQR A;  1GO7 P;  1GXD A;  3KMC A;  2J0T A;  4ZR5 A;  5D3C A;  1YOU A;  2POJ A;  2Z2D A;  3I7G A;  3E8R A;  5CXA A;  1A86 A;  2RJP A;  2OW9 A;  2CKI A;  3L0V A;  4I03 A;  1AYK A;  2MLS A;  3I7I A;  2FV5 A;  2MZE A;  1L6J A;  1R1I A;  4WK7 A;  3LGP A;  5I3M A;  5I12 A;  3TS4 A;  1OS9 A;  3LKA A;  5LAB A;  3VTG A;  1GO8 P;  1JKY A;  4L63 A;  4GUY A;  1EAK A;  1GE6 A;  2JSD A;  1MMQ A;  1DMT A;  2JIH A;  1QIB A;  4WF6 A;  1KUH A;  3LUM A;  2WO8 A;  2OXW A;  1HV5 A;  2O36 A;  2FV9 A;  1PWV A;  4HX3 A;  3HBV P;  4PKU A;  1IAB A;  4JA1 A;  2OVZ A;  3ELM A;  4IN9 A;  3TSK A;  1DTH A;  3F15 A;  1QJJ A;  2X3B A;  3G5C A;  2W15 A;  4AXQ A;  3DPF A;  1JAQ A;  2MZH A;  1HY7 A;  2K2G A;  3G42 A;  1G9K A;  1ZXV A;  2K9C A;  1O0Q A;  4G0D A;  5CUH A;  1RMZ A;  4DPE A;  1CK7 A;  1WNI A;  1USN A;  2DW0 A;  1R55 A;  4XCT A;  1G12 A;  1OO9 A;  1BUV M;  4A7B A;  1OS2 A;  2I47 A;  2USN A;  3ZVS A;  2ERP A;  4JPA A;  3DSL A; 
#chains in the Genus database with same CATH topology
 5D1T A;  1RM8 A;  3HY9 A;  3LIR A;  1HTD A;  1EB6 A;  1ZXC A;  1J7N A;  1SU3 A;  3USN A;  1GKC A;  3N2V A;  3HYG A;  1XUC A;  4PKS A;  1ZS0 A;  1JIW P;  3KRY A;  3V96 B;  1K7Q A;  4PKQ A;  1Q3A A;  2O3E A;  5I4O A;  1UMS A;  2HU6 A;  3RTS A;  1XAX A;  3KEK A;  3HDA P;  1C3I A;  1KUG A;  1TVI A;  4FXQ A;  4HMA A;  2W13 A;  4ILW D;  1SLN A;  3DTI A;  2JNP A;  4XM8 A;  1UTZ A;  1C8T A;  1ZTQ A;  1OM6 A;  4Q1L A;  5D1U A;  1XUD A;  4JP4 A;  2WOA A;  1XFW A;  2DDF A;  1G4K A;  1ROS A;  3LJT A;  3F19 A;  2YIG A;  2ERQ A;  2OW1 A;  4JIJ A;  1KBC A;  1YQY A;  1BSW A;  2OY2 A;  4GWM A;  5BPA A;  5I2Z A;  5D7W A;  3ZUK A;  1UEA A;  1MNC A;  4H76 A;  1D7X A;  1QJI A;  1SLM A;  3K7L A;  2OXZ A;  2D1O A;  2DW1 A;  1BQQ M;  1BKC A;  1B8Y A;  1SMP A;  3DTK A;  830C A;  3EHX A;  4GR3 A;  1BKC E;  3O2X A;  1OMJ A;  1YP1 A;  1XFY A;  2OXU A;  5B5O A;  1UMT A;  2WO9 A;  3TVC A;  3EWJ A;  1CGE A;  1GKD A;  4FXY P;  1FLS A;  3DL1 A;  2JT6 A;  4H1Q A;  4EFS A;  1CIZ A;  1SAT A;  1K7G A;  3UVC A;  2OI0 A;  4I35 A;  1FM1 A;  2N8R A;  1BZS A;  3U1R A;  1I73 A;  1MMR A;  1XUR A;  2OW0 A;  3F1A A;  1XFV A;  1SRP A;  4FVL A;  1KUK A;  4GF1 A;  4DV8 A;  3DWB A;  4H2E A;  4XBH A;  2YB9 A;  1BKC I;  5CZM A;  5I0L A;  3EHY A;  1BM6 A;  3EDH A;  3KEC A;  1IAC A;  2AIG P;  3ZXH A;  1QIC A;  2X7M A;  3B8Z A;  1ZVX A;  3K7N A;  3DPE A;  3HB2 P;  1C7K A;  2CLT A;  1JAN A;  3F18 A;  4GQL A;  4H82 A;  2SRT A;  4XM7 A;  5BOY A;  5L7F A;  3HBU P;  4WKI A;  3O64 A;  2Y6C A;  3P1V A;  3LE9 A;  3WV1 A;  4GR8 A;  1R1H A;  2W0D A;  1ATL A;  1AKL A;  1JAO A;  1QUA A;  3EDI A;  4XM6 A;  1HOV A;  3CKI A;  3KME A;  1CGF A;  2A8H A;  1ZP5 A;  1R1J A;  2Y6D A;  3WV3 A;  1KAP P;  3Q2G A;  4WKE A;  1IAA A;  4AYK A;  1HFS A;  3EDG A;  4H49 A;  2V4B A;  2QPJ A;  1ND1 A;  2OY4 A;  3LMC A;  2MZI A;  3N2U A;  1CXV A;  3KWV C;  1I1I P;  3AYU A;  2E2D A;  2E3X A;  3LK8 A;  1KUF A;  1JJ9 A;  2X3C A;  3LIK A;  4PKW A;  4L6T A;  1XM5 A;  4AIG A;  1H71 P;  3DTE A;  2DDY A;  1GE7 A;  4GWN A;  4QKZ A;  3LQ0 A;  3NX7 A;  1Y8J A;  4R3V A;  1KUI A;  5D1S A;  4L19 A;  5B5P A;  1Y0V A;  4PKT A;  2XS3 A;  3LJZ A;  2DW2 A;  2JT5 A;  1IAD A;  1IAE A;  3AYK A;  4DD8 A;  3P24 A;  4L7A A;  3LIL A;  1AST A;  1AF0 A;  3DNG A;  5L79 A;  2PJT A;  3KEJ A;  1O0T A;  4PKR A;  2J83 A;  1D8M A;  3B2Z A;  966C A;  1EUB A;  1G05 A;  1BQO A;  4H84 A;  1PWW A;  1Y93 A;  1JAP A;  1S4B P;  3OHL A;  1D8F A;  4G9L A;  2AYK A;  4ON1 A;  3VI1 A;  3LJG A;  3TT4 A;  3Q2H A;  3B92 A;  1XFZ A;  3BA0 A;  4J4M A;  2TCL A;  2KRJ A;  2OW2 A;  1CGL A;  1K7I A;  2W12 A;  3F17 A;  3F16 A;  1JK3 A;  5D2B A;  4AUO A;  1G49 A;  1XFU A;  2ERO A;  2MLR A;  1FBL A;  3KHI A;  4H3X A;  456C A;  2X3A A;  2XS4 A;  3HDB A;  4JQG A;  1HFC A;  4IUW A;  1MMB A;  1PWQ A;  1XFX A;  3HY7 A;  4GR0 A;  1D5J A;  1IAG A;  3L0T A;  4FU4 A;  2OVX A;  3LEA A;  5H8X A;  4WZV A;  1PWU A;  1B3D A;  3SHI A;  1OM8 A;  1JIZ A;  2D1N A;  1YCM A;  4CTH A;  2RJQ A;  4A3W A;  1GE5 A;  4DF9 A;  1A85 A;  2W14 A;  1JH1 A;  4IJO A;  3EDZ A;  1R54 A;  3OHO A;  3RTT A;  2OZR A;  1OM7 A;  3LQB A;  1BIW A;  5JMY A;  1Z3J A;  3GBO A;  4PKV A;  2L0R A;  1I76 A;  3MA2 A;  1CAQ A;  3WV2 A;  3AIG A;  5I43 A;  3LUN A;  1UTT A;  1PWP A;  1QIA A;  4H30 A;  1BUD A;  1MMP A;  5BOT A;  1CQR A;  1GO7 P;  1GXD A;  3KMC A;  2J0T A;  4ZR5 A;  5D3C A;  1YOU A;  2POJ A;  2Z2D A;  2YUF A;  3I7G A;  3E8R A;  5CXA A;  1A86 A;  2RJP A;  2OW9 A;  2CKI A;  3L0V A;  4I03 A;  1AYK A;  1OZ9 A;  2MLS A;  3I7I A;  2FV5 A;  2MZE A;  1L6J A;  1R1I A;  4WK7 A;  3LGP A;  5I3M A;  5I12 A;  3TS4 A;  1OS9 A;  3LKA A;  5LAB A;  3VTG A;  1GO8 P;  1JKY A;  4L63 A;  4GUY A;  1EAK A;  1GE6 A;  2JSD A;  1MMQ A;  1DMT A;  2JIH A;  1QIB A;  4WF6 A;  1KUH A;  3LUM A;  2WO8 A;  2OXW A;  1HV5 A;  2O36 A;  2FV9 A;  1PWV A;  4HX3 A;  3HBV P;  4PKU A;  1IAB A;  4JA1 A;  2OVZ A;  3ELM A;  4IN9 A;  3TSK A;  1DTH A;  3F15 A;  1QJJ A;  2X3B A;  3G5C A;  2W15 A;  4AXQ A;  3DPF A;  1JAQ A;  2MZH A;  1HY7 A;  2K2G A;  3G42 A;  1G9K A;  1ZXV A;  2K9C A;  1O0Q A;  4G0D A;  5CUH A;  1RMZ A;  4DPE A;  1CK7 A;  1WNI A;  1USN A;  2DW0 A;  1R55 A;  4XCT A;  1G12 A;  1OO9 A;  1BUV M;  4A7B A;  1OS2 A;  2I47 A;  2USN A;  3ZVS A;  2ERP A;  4JPA A;  3DSL A; 
#chains in the Genus database with same CATH homology
 5D1T A;  1RM8 A;  3HY9 A;  3LIR A;  1HTD A;  1EB6 A;  1ZXC A;  1J7N A;  1SU3 A;  3USN A;  1GKC A;  3N2V A;  3HYG A;  1XUC A;  4PKS A;  1ZS0 A;  1JIW P;  3KRY A;  3V96 B;  1K7Q A;  4PKQ A;  1Q3A A;  2O3E A;  5I4O A;  1UMS A;  2HU6 A;  3RTS A;  3KEK A;  3HDA P;  1C3I A;  1KUG A;  4FXQ A;  4HMA A;  2W13 A;  4ILW D;  1SLN A;  3DTI A;  2JNP A;  4XM8 A;  1UTZ A;  1C8T A;  1ZTQ A;  1OM6 A;  4Q1L A;  5D1U A;  1XUD A;  4JP4 A;  2WOA A;  1XFW A;  2DDF A;  1G4K A;  1ROS A;  3LJT A;  3F19 A;  2YIG A;  2ERQ A;  2OW1 A;  4JIJ A;  1KBC A;  1YQY A;  1BSW A;  2OY2 A;  4GWM A;  5BPA A;  5I2Z A;  5D7W A;  3ZUK A;  1UEA A;  1MNC A;  4H76 A;  1D7X A;  1QJI A;  1SLM A;  3K7L A;  2OXZ A;  2D1O A;  2DW1 A;  1BQQ M;  1BKC A;  1B8Y A;  1SMP A;  3DTK A;  830C A;  3EHX A;  4GR3 A;  1BKC E;  3O2X A;  1OMJ A;  1YP1 A;  1XFY A;  2OXU A;  5B5O A;  1UMT A;  2WO9 A;  3TVC A;  3EWJ A;  1CGE A;  1GKD A;  4FXY P;  1FLS A;  3DL1 A;  2JT6 A;  4H1Q A;  4EFS A;  1CIZ A;  1SAT A;  1K7G A;  3UVC A;  2OI0 A;  4I35 A;  1FM1 A;  2N8R A;  1BZS A;  3U1R A;  1I73 A;  1MMR A;  1XUR A;  2OW0 A;  3F1A A;  1XFV A;  1SRP A;  4FVL A;  1KUK A;  4GF1 A;  4DV8 A;  3DWB A;  4H2E A;  4XBH A;  2YB9 A;  1BKC I;  5CZM A;  5I0L A;  3EHY A;  1BM6 A;  3EDH A;  3KEC A;  1IAC A;  2AIG P;  3ZXH A;  1QIC A;  2X7M A;  3B8Z A;  1ZVX A;  3K7N A;  3DPE A;  3HB2 P;  1C7K A;  2CLT A;  1JAN A;  3F18 A;  4GQL A;  4H82 A;  2SRT A;  4XM7 A;  5BOY A;  5L7F A;  3HBU P;  4WKI A;  3O64 A;  2Y6C A;  3P1V A;  3LE9 A;  3WV1 A;  4GR8 A;  1R1H A;  2W0D A;  1ATL A;  1AKL A;  1JAO A;  1QUA A;  3EDI A;  4XM6 A;  1HOV A;  3CKI A;  3KME A;  1CGF A;  2A8H A;  1ZP5 A;  1R1J A;  2Y6D A;  3WV3 A;  1KAP P;  3Q2G A;  4WKE A;  1IAA A;  4AYK A;  1HFS A;  3EDG A;  4H49 A;  2V4B A;  2QPJ A;  1ND1 A;  2OY4 A;  3LMC A;  2MZI A;  3N2U A;  1CXV A;  3KWV C;  1I1I P;  3AYU A;  2E2D A;  2E3X A;  3LK8 A;  1KUF A;  1JJ9 A;  2X3C A;  3LIK A;  4PKW A;  4L6T A;  4AIG A;  1H71 P;  3DTE A;  2DDY A;  1GE7 A;  4GWN A;  4QKZ A;  3LQ0 A;  3NX7 A;  1Y8J A;  4R3V A;  1KUI A;  5D1S A;  4L19 A;  5B5P A;  1Y0V A;  4PKT A;  2XS3 A;  3LJZ A;  2DW2 A;  2JT5 A;  1IAD A;  1IAE A;  3AYK A;  4DD8 A;  3P24 A;  4L7A A;  3LIL A;  1AST A;  1AF0 A;  3DNG A;  5L79 A;  2PJT A;  3KEJ A;  1O0T A;  4PKR A;  2J83 A;  1D8M A;  3B2Z A;  966C A;  1EUB A;  1G05 A;  1BQO A;  4H84 A;  1PWW A;  1Y93 A;  1JAP A;  1S4B P;  3OHL A;  1D8F A;  4G9L A;  2AYK A;  4ON1 A;  3VI1 A;  3LJG A;  3TT4 A;  3Q2H A;  3B92 A;  1XFZ A;  3BA0 A;  4J4M A;  2TCL A;  2KRJ A;  2OW2 A;  1CGL A;  1K7I A;  2W12 A;  3F17 A;  3F16 A;  1JK3 A;  5D2B A;  4AUO A;  1G49 A;  1XFU A;  2ERO A;  2MLR A;  1FBL A;  3KHI A;  4H3X A;  456C A;  2X3A A;  2XS4 A;  3HDB A;  4JQG A;  1HFC A;  4IUW A;  1MMB A;  1PWQ A;  1XFX A;  3HY7 A;  4GR0 A;  1D5J A;  1IAG A;  3L0T A;  4FU4 A;  2OVX A;  3LEA A;  5H8X A;  4WZV A;  1PWU A;  1B3D A;  3SHI A;  1OM8 A;  1JIZ A;  2D1N A;  1YCM A;  4CTH A;  2RJQ A;  4A3W A;  1GE5 A;  4DF9 A;  1A85 A;  2W14 A;  1JH1 A;  4IJO A;  3EDZ A;  1R54 A;  3OHO A;  3RTT A;  2OZR A;  1OM7 A;  3LQB A;  1BIW A;  5JMY A;  1Z3J A;  3GBO A;  4PKV A;  2L0R A;  1I76 A;  3MA2 A;  1CAQ A;  3WV2 A;  3AIG A;  5I43 A;  3LUN A;  1UTT A;  1PWP A;  1QIA A;  4H30 A;  1BUD A;  1MMP A;  5BOT A;  1CQR A;  1GO7 P;  1GXD A;  3KMC A;  2J0T A;  4ZR5 A;  5D3C A;  1YOU A;  2POJ A;  2Z2D A;  2YUF A;  3I7G A;  3E8R A;  5CXA A;  1A86 A;  2RJP A;  2OW9 A;  2CKI A;  3L0V A;  4I03 A;  1AYK A;  2MLS A;  3I7I A;  2FV5 A;  2MZE A;  1L6J A;  1R1I A;  4WK7 A;  3LGP A;  5I3M A;  5I12 A;  3TS4 A;  1OS9 A;  3LKA A;  5LAB A;  3VTG A;  1GO8 P;  1JKY A;  4L63 A;  4GUY A;  1EAK A;  1GE6 A;  2JSD A;  1MMQ A;  1DMT A;  2JIH A;  1QIB A;  4WF6 A;  1KUH A;  3LUM A;  2WO8 A;  2OXW A;  1HV5 A;  2O36 A;  2FV9 A;  1PWV A;  4HX3 A;  3HBV P;  4PKU A;  1IAB A;  4JA1 A;  2OVZ A;  3ELM A;  4IN9 A;  3TSK A;  1DTH A;  3F15 A;  1QJJ A;  2X3B A;  3G5C A;  2W15 A;  4AXQ A;  3DPF A;  1JAQ A;  2MZH A;  1HY7 A;  2K2G A;  3G42 A;  1G9K A;  1ZXV A;  2K9C A;  1O0Q A;  4G0D A;  5CUH A;  1RMZ A;  4DPE A;  1CK7 A;  1WNI A;  1USN A;  2DW0 A;  1R55 A;  4XCT A;  1G12 A;  1OO9 A;  1BUV M;  4A7B A;  1OS2 A;  2I47 A;  2USN A;  3ZVS A;  2ERP A;  4JPA A;  3DSL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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