3KMEA

Crystal structure of catalytic domain of tace with phenyl-pyrrolidinyl-tartrate inhibitor
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
257
structure length
253
Chain Sequence
b'PDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TNF-alpha-converting enzyme
publication title The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 80
structure length 253
sequence length 257
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kmeA00
1JKYA 5H8XA 4PKRA 1GE6A 3F15A 3G5CA 3EHXA 5I43A 3TT4A 4XM6A 3HDAP 1OMJA 1OS9A 1MMPA 1XURA 2DW0A 3LIRA 2W13A 4HX3A 1R55A 1R1HA 1UMTA 4H49A 3KRYA 4FVLA 1PWUA 1IAAA 3DSLA 4PKSA 1HFSA 1HY7A 5I0LA 1BSWA 3LUMA 1XFYA 4GF1A 1K7GA 3CKIA 2RJQA 1JAPA 4GUYA 3EDHA 2J83A 2JT6A 2OW1A 4GR8A 4I03A 4DPEA 2FV9A 2MZHA 1R1JA 1JK3A 1GKCA 3BA0A 3E8RA 4XM7A 1QJIA 2FV5A 2QPJA 1G9KA 1S4BP 3USNA 3LK8A 1AKLA 3KMEA 1SRPA 3VTGA 1ASTA 2OXZA 1OS2A 1HTDA 1ND1A 1JANA 3I7GA 2X3AA 1BUDA 2D1OA 2E2DA 4IN9A 5CXAA 4H76A 5I12A 3WV3A 3AYKA 1ROSA 4PKUA 3HY9A 3O64A 1Y93A 4A7BA 2USNA 3MA2A 1ZVXA 4XBHA 3RTSA 1C8TA 1GE7A 4QKZA 1Q3AA 2DW1A 2X3BA 1IABA 3EDIA 2X3CA 1EB6A 4DV8A 3GBOA 3LQBA 3LJTA 1KUFA 456CA 1SLNA 1JJ9A 1MMBA 1WNIA 2A8HA 4WF6A 4ZR5A 2MZIA 1BQOA 1C3IA 1J7NA 2XS3A 3F17A 3WV2A 1K7QA 1DTHA 2SRTA 3DWBA 4FXQA 3LMCA 1IAEA 5I2ZA 4IJOA 4ILWD 1CIZA 2OW2A 1XFWA 1A86A 2OI0A 5L7FA 4H30A 2E3XA 5CUHA 4JIJA 3LJZA 2XS4A 2Y6CA 3OHOA 1B3DA 1XFUA 1FM1A 4L19A 1CXVA 4JQGA 1PWVA 3DPEA 4JP4A 1Y8JA 5CZMA 3P1VA 5I3MA 5BPAA 4DD8A 1AYKA 1ATLA 1SLMA 4IUWA 4PKWA 3AYUA 3HB2P 1CQRA 3Q2HA 1CK7A 1ZXCA 3KWVC 2DDFA 1Z3JA 2MZEA 1G05A 1IACA 2JSDA 3EWJA 3TVCA 4AIGA 2OW0A 2OVZA 1H71P 1HOVA 4Q1LA 2CLTA 2OVXA 1BQQM 4EFSA 5D7WA 830CA 3B8ZA 3HBVP 3I7IA 5I4OA 2CKIA 4ON1A 2O36A 3EHYA 1HFCA 1D8FA 2DDYA 3L0TA 4AXQA 3TS4A 1QUAA 3U1RA 3B2ZA 5BOYA 1UTZA 1XUCA 1KUGA 1CAQA 3UVCA 1RMZA 3OHLA 3O2XA 2JT5A 2RJPA 3F16A 1OO9A 1QIAA 2J0TA 1KUKA 5B5PA 5L79A 4GR0A 3F19A 1YCMA 1OM8A 2D1NA 4GWNA 1IAGA 4GQLA 5B5OA 1DMTA 3HBUP 3DL1A 1B8YA 1KUIA 5BOTA 1I1IP 1BKCE 1KBCA 1A85A 1OM7A 4WKIA 4FXYP 4DF9A 1JIWP 1FLSA 1JAQA 1MMQA 1GO8P 4GWMA 3F18A 1D8MA 2MLRA 5D1UA 1BKCA 4WKEA 4G0DA 2X7MA 1UTTA 4L6TA 1R1IA 3N2VA 3L0VA 2OXUA 5D1SA 4H1QA 1XFZA 1L6JA 1R54A 1GE5A 4WK7A 1G4KA 1I73A 1JAOA 2Y6DA 3B92A 1D5JA 1ZP5A 1I76A 3DNGA 2KRJA 3ELMA 4L63A 3LEAA 2OY2A 1SU3A 1YP1A 1GXDA 1BUVM 1BZSA 2O3EA 3ZXHA 2OY4A 1QICA 2OW9A 3NX7A 3V96B 1JIZA 3DPFA 1EAKA 1YOUA 1ZTQA 1USNA 1XFVA 2ERPA 1IADA 3VI1A 1OM6A 1QIBA 2POJA 1RM8A 1PWPA 2AIGP 3SHIA 3EDZA 3WV1A 3KECA 1ZXVA 3LQ0A 4AUOA 3P24A 2HU6A 966CA 3K7LA 1XUDA 4PKQA 2L0RA 2PJTA 4H2EA 2WOAA 1AF0A 1D7XA 2TCLA 3HY7A 3LGPA 1PWQA 2JIHA 1BIWA 4AYKA 2N8RA 1EUBA 3LIKA 4PKVA 2W15A 2OXWA 2W0DA 3KHIA 3HDBA 2I47A 1KAPP 1SMPA 3HYGA 2OZRA 3TSKA 1BKCI 2DW2A 1CGFA 1MMRA 1G49A 2W14A 1MNCA 1CGEA 3LKAA 1C7KA 1GKDA 4R3VA 4HMAA 1G12A 2WO9A 3LUNA 1JH1A 1KUHA 3Q2GA 4CTHA 2JNPA 1GO7P 4I35A 3RTTA 5LABA 1BM6A 3LJGA 2YIGA 1SATA 1QJJA 2K2GA 4H3XA 1ZS0A 2W12A 3LE9A 3K7NA 5D3CA 4J4MA 4WZVA 4FU4A 1O0TA 4JPAA 4JA1A 2YB9A 3AIGA 1HV5A 1FBLA 4H84A 4PKTA 3KMCA 3EDGA 4G9LA 1K7IA 3F1AA 4XM8A 3ZVSA 1UMSA 3ZUKA 3KEJA 2EROA 3KEKA 3G42A 5D1TA 5D2BA 2MLSA 2WO8A 1Y0VA 2V4BA 2Z2DA 2AYKA 2K9CA 4XCTA 4H82A 1CGLA 1O0QA 5JMYA 3LILA 1UEAA 3N2UA 1PWWA 1XFXA 4A3WA 2ERQA 4GR3A 1YQYA
chains in the Genus database with same CATH superfamily
3DTKA 1JKYA 5H8XA 4PKRA 1GE6A 3F15A 3G5CA 3EHXA 5I43A 3TT4A 4XM6A 3HDAP 1OMJA 1OS9A 1MMPA 1XURA 2DW0A 3LIRA 2W13A 4HX3A 1R55A 1R1HA 1UMTA 4H49A 3KRYA 4FVLA 1PWUA 1IAAA 3DSLA 4PKSA 1HFSA 1HY7A 5I0LA 1BSWA 3LUMA 1XFYA 4GF1A 1K7GA 3CKIA 2RJQA 1JAPA 4GUYA 3EDHA 2J83A 2JT6A 2OW1A 4GR8A 4I03A 4DPEA 2FV9A 2MZHA 1TVIA 1R1JA 1JK3A 1GKCA 3BA0A 3E8RA 4XM7A 1QJIA 2FV5A 2QPJA 1G9KA 1S4BP 3USNA 3LK8A 1AKLA 3KMEA 1SRPA 3VTGA 1ASTA 2OXZA 1OS2A 1HTDA 1ND1A 1JANA 3I7GA 2X3AA 1BUDA 2D1OA 2E2DA 4IN9A 5CXAA 4H76A 5I12A 3WV3A 3AYKA 1ROSA 4PKUA 3HY9A 3O64A 1Y93A 4A7BA 2USNA 3MA2A 1ZVXA 4XBHA 3RTSA 1C8TA 1GE7A 4QKZA 1Q3AA 2DW1A 2X3BA 1IABA 3EDIA 2X3CA 1EB6A 4DV8A 3GBOA 3LQBA 3LJTA 1KUFA 456CA 1SLNA 1JJ9A 1MMBA 1WNIA 2A8HA 4WF6A 4ZR5A 2MZIA 1BQOA 1C3IA 1J7NA 2XS3A 3F17A 3WV2A 1K7QA 1DTHA 2SRTA 4L7AA 3DWBA 4FXQA 3LMCA 1IAEA 5I2ZA 4IJOA 4ILWD 1CIZA 2OW2A 1XFWA 1A86A 2OI0A 5L7FA 4H30A 2E3XA 5CUHA 1OZ9A 4JIJA 3LJZA 2XS4A 2Y6CA 3OHOA 1B3DA 1XFUA 1FM1A 4L19A 1CXVA 4JQGA 1PWVA 3DPEA 4JP4A 1Y8JA 5CZMA 3P1VA 5I3MA 5BPAA 4DD8A 1AYKA 1ATLA 1SLMA 4IUWA 4PKWA 3AYUA 3HB2P 1CQRA 3Q2HA 1CK7A 1ZXCA 3KWVC 2DDFA 1Z3JA 2MZEA 1G05A 1IACA 2JSDA 3EWJA 3TVCA 4AIGA 2OW0A 2OVZA 1H71P 2YUFA 1HOVA 4Q1LA 2CLTA 2OVXA 1BQQM 4EFSA 5D7WA 830CA 3B8ZA 3HBVP 3I7IA 5I4OA 2CKIA 4ON1A 2O36A 3EHYA 1HFCA 1D8FA 2DDYA 3L0TA 4AXQA 3TS4A 1QUAA 3U1RA 3B2ZA 5BOYA 1UTZA 1XUCA 1KUGA 1CAQA 3UVCA 1RMZA 3OHLA 3O2XA 2JT5A 2RJPA 3F16A 1OO9A 1QIAA 2J0TA 1KUKA 1XM5A 5B5PA 5L79A 4GR0A 3F19A 1YCMA 1OM8A 2D1NA 4GWNA 1IAGA 4GQLA 5B5OA 1DMTA 3HBUP 3DL1A 1B8YA 1KUIA 5BOTA 1I1IP 1BKCE 1KBCA 1A85A 1OM7A 4WKIA 4FXYP 4DF9A 1JIWP 1FLSA 1JAQA 1MMQA 1GO8P 4GWMA 3F18A 1D8MA 2MLRA 5D1UA 1BKCA 4WKEA 4G0DA 2X7MA 1UTTA 4L6TA 1R1IA 3N2VA 3L0VA 2OXUA 5D1SA 4H1QA 1XFZA 1L6JA 1R54A 1GE5A 4WK7A 1G4KA 1I73A 1JAOA 2Y6DA 3B92A 1D5JA 1ZP5A 1I76A 3DNGA 2KRJA 3ELMA 4L63A 3LEAA 2OY2A 1SU3A 1YP1A 1GXDA 1BUVM 1BZSA 2O3EA 3ZXHA 2OY4A 1QICA 2OW9A 3NX7A 3V96B 1JIZA 3DPFA 1EAKA 1YOUA 1ZTQA 1USNA 1XFVA 2ERPA 1IADA 3VI1A 1OM6A 1QIBA 2POJA 1RM8A 1PWPA 2AIGP 3SHIA 3EDZA 3WV1A 3KECA 1ZXVA 3LQ0A 4AUOA 3P24A 2HU6A 966CA 3K7LA 1XUDA 4PKQA 2L0RA 2PJTA 4H2EA 2WOAA 1AF0A 1D7XA 2TCLA 3HY7A 3LGPA 1PWQA 2JIHA 1BIWA 4AYKA 2N8RA 1EUBA 3LIKA 4PKVA 2W15A 2OXWA 2W0DA 1XAXA 3KHIA 3HDBA 2I47A 1KAPP 1SMPA 3HYGA 2OZRA 3TSKA 1BKCI 2DW2A 1CGFA 1MMRA 1G49A 2W14A 1MNCA 1CGEA 3LKAA 1C7KA 1GKDA 4R3VA 4HMAA 1G12A 2WO9A 3LUNA 1JH1A 1KUHA 3Q2GA 4CTHA 2JNPA 1GO7P 4I35A 3RTTA 5LABA 1BM6A 3LJGA 2YIGA 1SATA 1QJJA 2K2GA 4H3XA 1ZS0A 2W12A 3LE9A 3K7NA 5D3CA 4J4MA 4WZVA 4FU4A 1O0TA 4JPAA 4JA1A 2YB9A 3AIGA 1HV5A 1FBLA 4H84A 4PKTA 3KMCA 3EDGA 4G9LA 1K7IA 3F1AA 4XM8A 3ZVSA 1UMSA 3ZUKA 3KEJA 2EROA 3KEKA 3G42A 5D1TA 5D2BA 2MLSA 2WO8A 1Y0VA 2V4BA 2Z2DA 2AYKA 2K9CA 4XCTA 4H82A 1CGLA 1O0QA 5JMYA 3LILA 3DTEA 1UEAA 3N2UA 1PWWA 1XFXA 4A3WA 2ERQA 4GR3A 1YQYA 3DTIA
chains in the Genus database with same CATH topology
3DTKA 1JKYA 5H8XA 4PKRA 1GE6A 3F15A 3G5CA 3EHXA 5I43A 3TT4A 4XM6A 3HDAP 1OMJA 1OS9A 1MMPA 1XURA 2DW0A 3LIRA 2W13A 4HX3A 1R55A 1R1HA 1UMTA 4H49A 3KRYA 4FVLA 1PWUA 1IAAA 3DSLA 4PKSA 1HFSA 1HY7A 5I0LA 1BSWA 3LUMA 1XFYA 4GF1A 1K7GA 3CKIA 2RJQA 1JAPA 4GUYA 3EDHA 2J83A 2JT6A 2OW1A 4GR8A 4I03A 4DPEA 2FV9A 2MZHA 1R1JA 1JK3A 1GKCA 3BA0A 3E8RA 4XM7A 1QJIA 2FV5A 2QPJA 1G9KA 1S4BP 3USNA 3LK8A 1AKLA 3KMEA 1SRPA 3VTGA 1ASTA 2OXZA 1OS2A 1HTDA 1ND1A 1JANA 3I7GA 2X3AA 1BUDA 2D1OA 2E2DA 4IN9A 5CXAA 4H76A 5I12A 3WV3A 3AYKA 1ROSA 4PKUA 3HY9A 3O64A 1Y93A 4A7BA 2USNA 3MA2A 1ZVXA 4XBHA 3RTSA 1C8TA 1GE7A 4QKZA 1Q3AA 2DW1A 2X3BA 1IABA 3EDIA 2X3CA 1EB6A 4DV8A 3GBOA 3LQBA 3LJTA 1KUFA 456CA 1SLNA 1JJ9A 1MMBA 1WNIA 2A8HA 4WF6A 4ZR5A 2MZIA 1BQOA 1C3IA 1J7NA 2XS3A 3F17A 3WV2A 1K7QA 1DTHA 2SRTA 4L7AA 3DWBA 4FXQA 3LMCA 1IAEA 5I2ZA 4IJOA 4ILWD 1CIZA 2OW2A 1XFWA 1A86A 2OI0A 5L7FA 4H30A 2E3XA 5CUHA 4JIJA 3LJZA 2XS4A 2Y6CA 3OHOA 1B3DA 1XFUA 1FM1A 4L19A 1CXVA 4JQGA 1PWVA 3DPEA 4JP4A 1Y8JA 5CZMA 3P1VA 5I3MA 5BPAA 4DD8A 1AYKA 1ATLA 1SLMA 4IUWA 4PKWA 3AYUA 3HB2P 1CQRA 3Q2HA 1CK7A 1ZXCA 3KWVC 2DDFA 1Z3JA 2MZEA 1G05A 1IACA 2JSDA 3EWJA 3TVCA 4AIGA 2OW0A 2OVZA 1H71P 2YUFA 1HOVA 4Q1LA 2CLTA 2OVXA 1BQQM 4EFSA 5D7WA 830CA 3B8ZA 3HBVP 3I7IA 5I4OA 2CKIA 4ON1A 2O36A 3EHYA 1HFCA 1D8FA 2DDYA 3L0TA 4AXQA 3TS4A 1QUAA 3U1RA 3B2ZA 5BOYA 1UTZA 1XUCA 1KUGA 1CAQA 3UVCA 1RMZA 3OHLA 3O2XA 2JT5A 2RJPA 3F16A 1OO9A 1QIAA 2J0TA 1KUKA 5B5PA 5L79A 4GR0A 3F19A 1YCMA 1OM8A 2D1NA 4GWNA 1IAGA 4GQLA 5B5OA 1DMTA 3HBUP 3DL1A 1B8YA 1KUIA 5BOTA 1I1IP 1BKCE 1KBCA 1A85A 1OM7A 4WKIA 4FXYP 4DF9A 1JIWP 1FLSA 1JAQA 1MMQA 1GO8P 4GWMA 3F18A 1D8MA 2MLRA 5D1UA 1BKCA 4WKEA 4G0DA 2X7MA 1UTTA 4L6TA 1R1IA 3N2VA 3L0VA 2OXUA 5D1SA 4H1QA 1XFZA 1L6JA 1R54A 1GE5A 4WK7A 1G4KA 1I73A 1JAOA 2Y6DA 3B92A 1D5JA 1ZP5A 1I76A 3DNGA 2KRJA 3ELMA 4L63A 3LEAA 2OY2A 1SU3A 1YP1A 1GXDA 1BUVM 1BZSA 2O3EA 3ZXHA 2OY4A 1QICA 2OW9A 3NX7A 3V96B 1JIZA 3DPFA 1EAKA 1YOUA 1ZTQA 1USNA 1XFVA 2ERPA 1IADA 3VI1A 1OM6A 1QIBA 2POJA 1RM8A 1PWPA 2AIGP 3SHIA 3EDZA 3WV1A 3KECA 1ZXVA 3LQ0A 4AUOA 3P24A 2HU6A 966CA 3K7LA 1XUDA 4PKQA 2L0RA 2PJTA 4H2EA 2WOAA 1AF0A 1D7XA 2TCLA 3HY7A 3LGPA 1PWQA 2JIHA 1BIWA 4AYKA 2N8RA 1EUBA 3LIKA 4PKVA 2W15A 2OXWA 2W0DA 3KHIA 3HDBA 2I47A 1KAPP 1SMPA 3HYGA 2OZRA 3TSKA 1BKCI 2DW2A 1CGFA 1MMRA 1G49A 2W14A 1MNCA 1CGEA 3LKAA 1C7KA 1GKDA 4R3VA 4HMAA 1G12A 2WO9A 3LUNA 1JH1A 1KUHA 3Q2GA 4CTHA 2JNPA 1GO7P 4I35A 3RTTA 5LABA 1BM6A 3LJGA 2YIGA 1SATA 1QJJA 2K2GA 4H3XA 1ZS0A 2W12A 3LE9A 3K7NA 5D3CA 4J4MA 4WZVA 4FU4A 1O0TA 4JPAA 4JA1A 2YB9A 3AIGA 1HV5A 1FBLA 4H84A 4PKTA 3KMCA 3EDGA 4G9LA 1K7IA 3F1AA 4XM8A 3ZVSA 1UMSA 3ZUKA 3KEJA 2EROA 3KEKA 3G42A 5D1TA 5D2BA 2MLSA 2WO8A 1Y0VA 2V4BA 2Z2DA 2AYKA 2K9CA 4XCTA 4H82A 1CGLA 1O0QA 5JMYA 3LILA 3DTEA 1UEAA 3N2UA 1PWWA 1XFXA 4A3WA 2ERQA 4GR3A 1YQYA 3DTIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JKY A;  5H8X A;  4PKR A;  1GE6 A;  3F15 A;  3G5C A;  3EHX A;  5I43 A;  3TT4 A;  4XM6 A;  3HDA P;  1OMJ A;  1OS9 A;  1MMP A;  1XUR A;  2DW0 A;  3LIR A;  2W13 A;  4HX3 A;  1R55 A;  1R1H A;  1UMT A;  4H49 A;  3KRY A;  4FVL A;  1PWU A;  1IAA A;  3DSL A;  4PKS A;  1HFS A;  1HY7 A;  5I0L A;  1BSW A;  3LUM A;  1XFY A;  4GF1 A;  1K7G A;  3CKI A;  2RJQ A;  1JAP A;  4GUY A;  3EDH A;  2J83 A;  2JT6 A;  2OW1 A;  4GR8 A;  4I03 A;  4DPE A;  2FV9 A;  2MZH A;  1R1J A;  1JK3 A;  1GKC A;  3BA0 A;  3E8R A;  4XM7 A;  1QJI A;  2FV5 A;  2QPJ A;  1G9K A;  1S4B P;  3USN A;  3LK8 A;  1AKL A;  3KME A;  1SRP A;  3VTG A;  1AST A;  2OXZ A;  1OS2 A;  1HTD A;  1ND1 A;  1JAN A;  3I7G A;  2X3A A;  1BUD A;  2D1O A;  2E2D A;  4IN9 A;  5CXA A;  4H76 A;  5I12 A;  3WV3 A;  3AYK A;  1ROS A;  4PKU A;  3HY9 A;  3O64 A;  1Y93 A;  4A7B A;  2USN A;  3MA2 A;  1ZVX A;  4XBH A;  3RTS A;  1C8T A;  1GE7 A;  4QKZ A;  1Q3A A;  2DW1 A;  2X3B A;  1IAB A;  3EDI A;  2X3C A;  1EB6 A;  4DV8 A;  3GBO A;  3LQB A;  3LJT A;  1KUF A;  456C A;  1SLN A;  1JJ9 A;  1MMB A;  1WNI A;  2A8H A;  4WF6 A;  4ZR5 A;  2MZI A;  1BQO A;  1C3I A;  1J7N A;  2XS3 A;  3F17 A;  3WV2 A;  1K7Q A;  1DTH A;  2SRT A;  3DWB A;  4FXQ A;  3LMC A;  1IAE A;  5I2Z A;  4IJO A;  4ILW D;  1CIZ A;  2OW2 A;  1XFW A;  1A86 A;  2OI0 A;  5L7F A;  4H30 A;  2E3X A;  5CUH A;  4JIJ A;  3LJZ A;  2XS4 A;  2Y6C A;  3OHO A;  1B3D A;  1XFU A;  1FM1 A;  4L19 A;  1CXV A;  4JQG A;  1PWV A;  3DPE A;  4JP4 A;  1Y8J A;  5CZM A;  3P1V A;  5I3M A;  5BPA A;  4DD8 A;  1AYK A;  1ATL A;  1SLM A;  4IUW A;  4PKW A;  3AYU A;  3HB2 P;  1CQR A;  3Q2H A;  1CK7 A;  1ZXC A;  3KWV C;  2DDF A;  1Z3J A;  2MZE A;  1G05 A;  1IAC A;  2JSD A;  3EWJ A;  3TVC A;  4AIG A;  2OW0 A;  2OVZ A;  1H71 P;  1HOV A;  4Q1L A;  2CLT A;  2OVX A;  1BQQ M;  4EFS A;  5D7W A;  830C A;  3B8Z A;  3HBV P;  3I7I A;  5I4O A;  2CKI A;  4ON1 A;  2O36 A;  3EHY A;  1HFC A;  1D8F A;  2DDY A;  3L0T A;  4AXQ A;  3TS4 A;  1QUA A;  3U1R A;  3B2Z A;  5BOY A;  1UTZ A;  1XUC A;  1KUG A;  1CAQ A;  3UVC A;  1RMZ A;  3OHL A;  3O2X A;  2JT5 A;  2RJP A;  3F16 A;  1OO9 A;  1QIA A;  2J0T A;  1KUK A;  5B5P A;  5L79 A;  4GR0 A;  3F19 A;  1YCM A;  1OM8 A;  2D1N A;  4GWN A;  1IAG A;  4GQL A;  5B5O A;  1DMT A;  3HBU P;  3DL1 A;  1B8Y A;  1KUI A;  5BOT A;  1I1I P;  1BKC E;  1KBC A;  1A85 A;  1OM7 A;  4WKI A;  4FXY P;  4DF9 A;  1JIW P;  1FLS A;  1JAQ A;  1MMQ A;  1GO8 P;  4GWM A;  3F18 A;  1D8M A;  2MLR A;  5D1U A;  1BKC A;  4WKE A;  4G0D A;  2X7M A;  1UTT A;  4L6T A;  1R1I A;  3N2V A;  3L0V A;  2OXU A;  5D1S A;  4H1Q A;  1XFZ A;  1L6J A;  1R54 A;  1GE5 A;  4WK7 A;  1G4K A;  1I73 A;  1JAO A;  2Y6D A;  3B92 A;  1D5J A;  1ZP5 A;  1I76 A;  3DNG A;  2KRJ A;  3ELM A;  4L63 A;  3LEA A;  2OY2 A;  1SU3 A;  1YP1 A;  1GXD A;  1BUV M;  1BZS A;  2O3E A;  3ZXH A;  2OY4 A;  1QIC A;  2OW9 A;  3NX7 A;  3V96 B;  1JIZ A;  3DPF A;  1EAK A;  1YOU A;  1ZTQ A;  1USN A;  1XFV A;  2ERP A;  1IAD A;  3VI1 A;  1OM6 A;  1QIB A;  2POJ A;  1RM8 A;  1PWP A;  2AIG P;  3SHI A;  3EDZ A;  3WV1 A;  3KEC A;  1ZXV A;  3LQ0 A;  4AUO A;  3P24 A;  2HU6 A;  966C A;  3K7L A;  1XUD A;  4PKQ A;  2L0R A;  2PJT A;  4H2E A;  2WOA A;  1AF0 A;  1D7X A;  2TCL A;  3HY7 A;  3LGP A;  1PWQ A;  2JIH A;  1BIW A;  4AYK A;  2N8R A;  1EUB A;  3LIK A;  4PKV A;  2W15 A;  2OXW A;  2W0D A;  3KHI A;  3HDB A;  2I47 A;  1KAP P;  1SMP A;  3HYG A;  2OZR A;  3TSK A;  1BKC I;  2DW2 A;  1CGF A;  1MMR A;  1G49 A;  2W14 A;  1MNC A;  1CGE A;  3LKA A;  1C7K A;  1GKD A;  4R3V A;  4HMA A;  1G12 A;  2WO9 A;  3LUN A;  1JH1 A;  1KUH A;  3Q2G A;  4CTH A;  2JNP A;  1GO7 P;  4I35 A;  3RTT A;  5LAB A;  1BM6 A;  3LJG A;  2YIG A;  1SAT A;  1QJJ A;  2K2G A;  4H3X A;  1ZS0 A;  2W12 A;  3LE9 A;  3K7N A;  5D3C A;  4J4M A;  4WZV A;  4FU4 A;  1O0T A;  4JPA A;  4JA1 A;  2YB9 A;  3AIG A;  1HV5 A;  1FBL A;  4H84 A;  4PKT A;  3KMC A;  3EDG A;  4G9L A;  1K7I A;  3F1A A;  4XM8 A;  3ZVS A;  1UMS A;  3ZUK A;  3KEJ A;  2ERO A;  3KEK A;  3G42 A;  5D1T A;  5D2B A;  2MLS A;  2WO8 A;  1Y0V A;  2V4B A;  2Z2D A;  2AYK A;  2K9C A;  4XCT A;  4H82 A;  1CGL A;  1O0Q A;  5JMY A;  3LIL A;  1UEA A;  3N2U A;  1PWW A;  1XFX A;  4A3W A;  2ERQ A;  4GR3 A;  1YQY A; 
#chains in the Genus database with same CATH topology
 3DTK A;  1JKY A;  5H8X A;  4PKR A;  1GE6 A;  3F15 A;  3G5C A;  3EHX A;  5I43 A;  3TT4 A;  4XM6 A;  3HDA P;  1OMJ A;  1OS9 A;  1MMP A;  1XUR A;  2DW0 A;  3LIR A;  2W13 A;  4HX3 A;  1R55 A;  1R1H A;  1UMT A;  4H49 A;  3KRY A;  4FVL A;  1PWU A;  1IAA A;  3DSL A;  4PKS A;  1HFS A;  1HY7 A;  5I0L A;  1BSW A;  3LUM A;  1XFY A;  4GF1 A;  1K7G A;  3CKI A;  2RJQ A;  1JAP A;  4GUY A;  3EDH A;  2J83 A;  2JT6 A;  2OW1 A;  4GR8 A;  4I03 A;  4DPE A;  2FV9 A;  2MZH A;  1TVI A;  1R1J A;  1JK3 A;  1GKC A;  3BA0 A;  3E8R A;  4XM7 A;  1QJI A;  2FV5 A;  2QPJ A;  1G9K A;  1S4B P;  3USN A;  3LK8 A;  1AKL A;  3KME A;  1SRP A;  3VTG A;  1AST A;  2OXZ A;  1OS2 A;  1HTD A;  1ND1 A;  1JAN A;  3I7G A;  2X3A A;  1BUD A;  2D1O A;  2E2D A;  4IN9 A;  5CXA A;  4H76 A;  5I12 A;  3WV3 A;  3AYK A;  1ROS A;  4PKU A;  3HY9 A;  3O64 A;  1Y93 A;  4A7B A;  2USN A;  3MA2 A;  1ZVX A;  4XBH A;  3RTS A;  1C8T A;  1GE7 A;  4QKZ A;  1Q3A A;  2DW1 A;  2X3B A;  1IAB A;  3EDI A;  2X3C A;  1EB6 A;  4DV8 A;  3GBO A;  3LQB A;  3LJT A;  1KUF A;  456C A;  1SLN A;  1JJ9 A;  1MMB A;  1WNI A;  2A8H A;  4WF6 A;  4ZR5 A;  2MZI A;  1BQO A;  1C3I A;  1J7N A;  2XS3 A;  3F17 A;  3WV2 A;  1K7Q A;  1DTH A;  2SRT A;  4L7A A;  3DWB A;  4FXQ A;  3LMC A;  1IAE A;  5I2Z A;  4IJO A;  4ILW D;  1CIZ A;  2OW2 A;  1XFW A;  1A86 A;  2OI0 A;  5L7F A;  4H30 A;  2E3X A;  5CUH A;  1OZ9 A;  4JIJ A;  3LJZ A;  2XS4 A;  2Y6C A;  3OHO A;  1B3D A;  1XFU A;  1FM1 A;  4L19 A;  1CXV A;  4JQG A;  1PWV A;  3DPE A;  4JP4 A;  1Y8J A;  5CZM A;  3P1V A;  5I3M A;  5BPA A;  4DD8 A;  1AYK A;  1ATL A;  1SLM A;  4IUW A;  4PKW A;  3AYU A;  3HB2 P;  1CQR A;  3Q2H A;  1CK7 A;  1ZXC A;  3KWV C;  2DDF A;  1Z3J A;  2MZE A;  1G05 A;  1IAC A;  2JSD A;  3EWJ A;  3TVC A;  4AIG A;  2OW0 A;  2OVZ A;  1H71 P;  2YUF A;  1HOV A;  4Q1L A;  2CLT A;  2OVX A;  1BQQ M;  4EFS A;  5D7W A;  830C A;  3B8Z A;  3HBV P;  3I7I A;  5I4O A;  2CKI A;  4ON1 A;  2O36 A;  3EHY A;  1HFC A;  1D8F A;  2DDY A;  3L0T A;  4AXQ A;  3TS4 A;  1QUA A;  3U1R A;  3B2Z A;  5BOY A;  1UTZ A;  1XUC A;  1KUG A;  1CAQ A;  3UVC A;  1RMZ A;  3OHL A;  3O2X A;  2JT5 A;  2RJP A;  3F16 A;  1OO9 A;  1QIA A;  2J0T A;  1KUK A;  1XM5 A;  5B5P A;  5L79 A;  4GR0 A;  3F19 A;  1YCM A;  1OM8 A;  2D1N A;  4GWN A;  1IAG A;  4GQL A;  5B5O A;  1DMT A;  3HBU P;  3DL1 A;  1B8Y A;  1KUI A;  5BOT A;  1I1I P;  1BKC E;  1KBC A;  1A85 A;  1OM7 A;  4WKI A;  4FXY P;  4DF9 A;  1JIW P;  1FLS A;  1JAQ A;  1MMQ A;  1GO8 P;  4GWM A;  3F18 A;  1D8M A;  2MLR A;  5D1U A;  1BKC A;  4WKE A;  4G0D A;  2X7M A;  1UTT A;  4L6T A;  1R1I A;  3N2V A;  3L0V A;  2OXU A;  5D1S A;  4H1Q A;  1XFZ A;  1L6J A;  1R54 A;  1GE5 A;  4WK7 A;  1G4K A;  1I73 A;  1JAO A;  2Y6D A;  3B92 A;  1D5J A;  1ZP5 A;  1I76 A;  3DNG A;  2KRJ A;  3ELM A;  4L63 A;  3LEA A;  2OY2 A;  1SU3 A;  1YP1 A;  1GXD A;  1BUV M;  1BZS A;  2O3E A;  3ZXH A;  2OY4 A;  1QIC A;  2OW9 A;  3NX7 A;  3V96 B;  1JIZ A;  3DPF A;  1EAK A;  1YOU A;  1ZTQ A;  1USN A;  1XFV A;  2ERP A;  1IAD A;  3VI1 A;  1OM6 A;  1QIB A;  2POJ A;  1RM8 A;  1PWP A;  2AIG P;  3SHI A;  3EDZ A;  3WV1 A;  3KEC A;  1ZXV A;  3LQ0 A;  4AUO A;  3P24 A;  2HU6 A;  966C A;  3K7L A;  1XUD A;  4PKQ A;  2L0R A;  2PJT A;  4H2E A;  2WOA A;  1AF0 A;  1D7X A;  2TCL A;  3HY7 A;  3LGP A;  1PWQ A;  2JIH A;  1BIW A;  4AYK A;  2N8R A;  1EUB A;  3LIK A;  4PKV A;  2W15 A;  2OXW A;  2W0D A;  1XAX A;  3KHI A;  3HDB A;  2I47 A;  1KAP P;  1SMP A;  3HYG A;  2OZR A;  3TSK A;  1BKC I;  2DW2 A;  1CGF A;  1MMR A;  1G49 A;  2W14 A;  1MNC A;  1CGE A;  3LKA A;  1C7K A;  1GKD A;  4R3V A;  4HMA A;  1G12 A;  2WO9 A;  3LUN A;  1JH1 A;  1KUH A;  3Q2G A;  4CTH A;  2JNP A;  1GO7 P;  4I35 A;  3RTT A;  5LAB A;  1BM6 A;  3LJG A;  2YIG A;  1SAT A;  1QJJ A;  2K2G A;  4H3X A;  1ZS0 A;  2W12 A;  3LE9 A;  3K7N A;  5D3C A;  4J4M A;  4WZV A;  4FU4 A;  1O0T A;  4JPA A;  4JA1 A;  2YB9 A;  3AIG A;  1HV5 A;  1FBL A;  4H84 A;  4PKT A;  3KMC A;  3EDG A;  4G9L A;  1K7I A;  3F1A A;  4XM8 A;  3ZVS A;  1UMS A;  3ZUK A;  3KEJ A;  2ERO A;  3KEK A;  3G42 A;  5D1T A;  5D2B A;  2MLS A;  2WO8 A;  1Y0V A;  2V4B A;  2Z2D A;  2AYK A;  2K9C A;  4XCT A;  4H82 A;  1CGL A;  1O0Q A;  5JMY A;  3LIL A;  3DTE A;  1UEA A;  3N2U A;  1PWW A;  1XFX A;  4A3W A;  2ERQ A;  4GR3 A;  1YQY A;  3DTI A; 
#chains in the Genus database with same CATH homology
 3DTK A;  1JKY A;  5H8X A;  4PKR A;  1GE6 A;  3F15 A;  3G5C A;  3EHX A;  5I43 A;  3TT4 A;  4XM6 A;  3HDA P;  1OMJ A;  1OS9 A;  1MMP A;  1XUR A;  2DW0 A;  3LIR A;  2W13 A;  4HX3 A;  1R55 A;  1R1H A;  1UMT A;  4H49 A;  3KRY A;  4FVL A;  1PWU A;  1IAA A;  3DSL A;  4PKS A;  1HFS A;  1HY7 A;  5I0L A;  1BSW A;  3LUM A;  1XFY A;  4GF1 A;  1K7G A;  3CKI A;  2RJQ A;  1JAP A;  4GUY A;  3EDH A;  2J83 A;  2JT6 A;  2OW1 A;  4GR8 A;  4I03 A;  4DPE A;  2FV9 A;  2MZH A;  1R1J A;  1JK3 A;  1GKC A;  3BA0 A;  3E8R A;  4XM7 A;  1QJI A;  2FV5 A;  2QPJ A;  1G9K A;  1S4B P;  3USN A;  3LK8 A;  1AKL A;  3KME A;  1SRP A;  3VTG A;  1AST A;  2OXZ A;  1OS2 A;  1HTD A;  1ND1 A;  1JAN A;  3I7G A;  2X3A A;  1BUD A;  2D1O A;  2E2D A;  4IN9 A;  5CXA A;  4H76 A;  5I12 A;  3WV3 A;  3AYK A;  1ROS A;  4PKU A;  3HY9 A;  3O64 A;  1Y93 A;  4A7B A;  2USN A;  3MA2 A;  1ZVX A;  4XBH A;  3RTS A;  1C8T A;  1GE7 A;  4QKZ A;  1Q3A A;  2DW1 A;  2X3B A;  1IAB A;  3EDI A;  2X3C A;  1EB6 A;  4DV8 A;  3GBO A;  3LQB A;  3LJT A;  1KUF A;  456C A;  1SLN A;  1JJ9 A;  1MMB A;  1WNI A;  2A8H A;  4WF6 A;  4ZR5 A;  2MZI A;  1BQO A;  1C3I A;  1J7N A;  2XS3 A;  3F17 A;  3WV2 A;  1K7Q A;  1DTH A;  2SRT A;  4L7A A;  3DWB A;  4FXQ A;  3LMC A;  1IAE A;  5I2Z A;  4IJO A;  4ILW D;  1CIZ A;  2OW2 A;  1XFW A;  1A86 A;  2OI0 A;  5L7F A;  4H30 A;  2E3X A;  5CUH A;  4JIJ A;  3LJZ A;  2XS4 A;  2Y6C A;  3OHO A;  1B3D A;  1XFU A;  1FM1 A;  4L19 A;  1CXV A;  4JQG A;  1PWV A;  3DPE A;  4JP4 A;  1Y8J A;  5CZM A;  3P1V A;  5I3M A;  5BPA A;  4DD8 A;  1AYK A;  1ATL A;  1SLM A;  4IUW A;  4PKW A;  3AYU A;  3HB2 P;  1CQR A;  3Q2H A;  1CK7 A;  1ZXC A;  3KWV C;  2DDF A;  1Z3J A;  2MZE A;  1G05 A;  1IAC A;  2JSD A;  3EWJ A;  3TVC A;  4AIG A;  2OW0 A;  2OVZ A;  1H71 P;  2YUF A;  1HOV A;  4Q1L A;  2CLT A;  2OVX A;  1BQQ M;  4EFS A;  5D7W A;  830C A;  3B8Z A;  3HBV P;  3I7I A;  5I4O A;  2CKI A;  4ON1 A;  2O36 A;  3EHY A;  1HFC A;  1D8F A;  2DDY A;  3L0T A;  4AXQ A;  3TS4 A;  1QUA A;  3U1R A;  3B2Z A;  5BOY A;  1UTZ A;  1XUC A;  1KUG A;  1CAQ A;  3UVC A;  1RMZ A;  3OHL A;  3O2X A;  2JT5 A;  2RJP A;  3F16 A;  1OO9 A;  1QIA A;  2J0T A;  1KUK A;  5B5P A;  5L79 A;  4GR0 A;  3F19 A;  1YCM A;  1OM8 A;  2D1N A;  4GWN A;  1IAG A;  4GQL A;  5B5O A;  1DMT A;  3HBU P;  3DL1 A;  1B8Y A;  1KUI A;  5BOT A;  1I1I P;  1BKC E;  1KBC A;  1A85 A;  1OM7 A;  4WKI A;  4FXY P;  4DF9 A;  1JIW P;  1FLS A;  1JAQ A;  1MMQ A;  1GO8 P;  4GWM A;  3F18 A;  1D8M A;  2MLR A;  5D1U A;  1BKC A;  4WKE A;  4G0D A;  2X7M A;  1UTT A;  4L6T A;  1R1I A;  3N2V A;  3L0V A;  2OXU A;  5D1S A;  4H1Q A;  1XFZ A;  1L6J A;  1R54 A;  1GE5 A;  4WK7 A;  1G4K A;  1I73 A;  1JAO A;  2Y6D A;  3B92 A;  1D5J A;  1ZP5 A;  1I76 A;  3DNG A;  2KRJ A;  3ELM A;  4L63 A;  3LEA A;  2OY2 A;  1SU3 A;  1YP1 A;  1GXD A;  1BUV M;  1BZS A;  2O3E A;  3ZXH A;  2OY4 A;  1QIC A;  2OW9 A;  3NX7 A;  3V96 B;  1JIZ A;  3DPF A;  1EAK A;  1YOU A;  1ZTQ A;  1USN A;  1XFV A;  2ERP A;  1IAD A;  3VI1 A;  1OM6 A;  1QIB A;  2POJ A;  1RM8 A;  1PWP A;  2AIG P;  3SHI A;  3EDZ A;  3WV1 A;  3KEC A;  1ZXV A;  3LQ0 A;  4AUO A;  3P24 A;  2HU6 A;  966C A;  3K7L A;  1XUD A;  4PKQ A;  2L0R A;  2PJT A;  4H2E A;  2WOA A;  1AF0 A;  1D7X A;  2TCL A;  3HY7 A;  3LGP A;  1PWQ A;  2JIH A;  1BIW A;  4AYK A;  2N8R A;  1EUB A;  3LIK A;  4PKV A;  2W15 A;  2OXW A;  2W0D A;  3KHI A;  3HDB A;  2I47 A;  1KAP P;  1SMP A;  3HYG A;  2OZR A;  3TSK A;  1BKC I;  2DW2 A;  1CGF A;  1MMR A;  1G49 A;  2W14 A;  1MNC A;  1CGE A;  3LKA A;  1C7K A;  1GKD A;  4R3V A;  4HMA A;  1G12 A;  2WO9 A;  3LUN A;  1JH1 A;  1KUH A;  3Q2G A;  4CTH A;  2JNP A;  1GO7 P;  4I35 A;  3RTT A;  5LAB A;  1BM6 A;  3LJG A;  2YIG A;  1SAT A;  1QJJ A;  2K2G A;  4H3X A;  1ZS0 A;  2W12 A;  3LE9 A;  3K7N A;  5D3C A;  4J4M A;  4WZV A;  4FU4 A;  1O0T A;  4JPA A;  4JA1 A;  2YB9 A;  3AIG A;  1HV5 A;  1FBL A;  4H84 A;  4PKT A;  3KMC A;  3EDG A;  4G9L A;  1K7I A;  3F1A A;  4XM8 A;  3ZVS A;  1UMS A;  3ZUK A;  3KEJ A;  2ERO A;  3KEK A;  3G42 A;  5D1T A;  5D2B A;  2MLS A;  2WO8 A;  1Y0V A;  2V4B A;  2Z2D A;  2AYK A;  2K9C A;  4XCT A;  4H82 A;  1CGL A;  1O0Q A;  5JMY A;  3LIL A;  3DTE A;  1UEA A;  3N2U A;  1PWW A;  1XFX A;  4A3W A;  2ERQ A;  4GR3 A;  1YQY A;  3DTI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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