3KMUB

Crystal structure of the ilk/alpha-parvin core complex (apo)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
124
structure length
124
Chain Sequence
AFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Integrin-linked kinase
total genus 35
structure length 124
sequence length 124
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3kmuB00
1DXXA 3JALM 1SH6A 3KMWB 5L0OA 3HOPA 2WFNA 3JARM 1WKUA 2EYNA 1PXYA 2D87A 1WYNA 5A38A 1WYOA 3KMUB 4Q59A 4EDLA 2L3GA 2E9KA 1V5KA 2K3SA 2VZIB 1AA2A 2VZGB 4B7LA 2R8UA 3I6XA 1AOAA 4Q57B 1P2XA 1SH5A 4TXKA 2QJXA 5BVRA 1QAGA 3HOCA 1UJOA 2D89A 3CO1A 2WA7A 1H67A 2QJZA 5A4BA 3F7PA 2D88A 2RR8A 1BHDA 4EDNA 1WIXA 2DK9A 5J8EA 2D86A 1WYLA 2VZDA 3JAKM 1WJOA 3REPB 2D85A 1UEGA 1PA7A 3KY9A 2EE7A 1P5SA 1WYQA 1MB8A 2YRNA 2EYIA 1TJTA 1WYMA 1WYRA 4TXIA 4EDMA 2WA6A 1RT8A 2JV9A 3FERA 3HORA 1VKAA 5A36A 2K2RA 1BKRA 4Q58A 2VZCA 1WYPA 2R0OA 2WA5A 5A37A
chains in the Genus database with same CATH superfamily
1DXXA 3JALM 1SH6A 3KMWB 5L0OA 3HOPA 2WFNA 3JARM 2WDTA 1WKUA 2IGPA 2EYNA 1PXYA 2D87A 1WYNA 5A38A 1WYOA 3KMUB 4Q59A 4EDLA 2L3GA 2E9KA 4DDPA 1V5KA 2K3SA 2WE6A 2VZIB 1AA2A 2HKPA 1EUVA 2VZGB 4B7LA 2R8UA 3I6XA 1AOAA 4Q57B 3EAYA 1P2XA 1SH5A 4TXKA 2QJXA 5BVRA 4LVPA 1QAGA 5FMTA 3HOCA 1UJOA 2D89A 3CO1A 2WA7A 1H67A 2QJZA 2VE7C 5A4BA 3F7PA 2D88A 2RR8A 1BHDA 4EDNA 1WIXA 2DK9A 5J8EA 2D86A 1WYLA 2VZDA 2HL8A 3JAKM 1WJOA 3REPB 2D85A 1UEGA 1PA7A 3VP7A 3KY9A 2EE7A 1P5SA 1WYQA 1MB8A 4LVRA 2YRNA 2EYIA 1TJTA 2HL9A 1WYMA 1WYRA 4TXIA 4EDMA 2WA6A 1RT8A 2JV9A 3FERA 3HORA 1VKAA 5A36A 2K2RA 1BKRA 4Q58A 2VE7A 5FMUA 2VZCA 2EQOA 1WYPA 2R0OA 2WA5A 5A37A
chains in the Genus database with same CATH topology
1DXXA 3JALM 1SH6A 3KMWB 5L0OA 3HOPA 2WFNA 3JARM 1WKUA 2EYNA 1PXYA 2D87A 1WYNA 5A38A 1WYOA 3KMUB 4Q59A 4EDLA 2L3GA 2E9KA 1V5KA 2K3SA 2VZIB 1AA2A 2VZGB 4B7LA 2R8UA 3I6XA 1AOAA 4Q57B 1P2XA 1SH5A 4TXKA 2QJXA 5BVRA 1QAGA 3HOCA 1UJOA 2D89A 3CO1A 2WA7A 1H67A 2QJZA 5A4BA 3F7PA 2D88A 2RR8A 1BHDA 4EDNA 1WIXA 2DK9A 5J8EA 2D86A 1WYLA 2VZDA 3JAKM 1WJOA 3REPB 2D85A 1UEGA 1PA7A 3KY9A 2EE7A 1P5SA 1WYQA 1MB8A 2YRNA 2EYIA 1TJTA 1WYMA 1WYRA 4TXIA 4EDMA 2WA6A 1RT8A 2JV9A 3FERA 3HORA 1VKAA 5A36A 2K2RA 1BKRA 4Q58A 2VZCA 1WYPA 2R0OA 2WA5A 5A37A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DXX A;  3JAL M;  1SH6 A;  3KMW B;  5L0O A;  3HOP A;  2WFN A;  3JAR M;  1WKU A;  2EYN A;  1PXY A;  2D87 A;  1WYN A;  5A38 A;  1WYO A;  3KMU B;  4Q59 A;  4EDL A;  2L3G A;  2E9K A;  1V5K A;  2K3S A;  2VZI B;  1AA2 A;  2VZG B;  4B7L A;  2R8U A;  3I6X A;  1AOA A;  4Q57 B;  1P2X A;  1SH5 A;  4TXK A;  2QJX A;  5BVR A;  1QAG A;  3HOC A;  1UJO A;  2D89 A;  3CO1 A;  2WA7 A;  1H67 A;  2QJZ A;  5A4B A;  3F7P A;  2D88 A;  2RR8 A;  1BHD A;  4EDN A;  1WIX A;  2DK9 A;  5J8E A;  2D86 A;  1WYL A;  2VZD A;  3JAK M;  1WJO A;  3REP B;  2D85 A;  1UEG A;  1PA7 A;  3KY9 A;  2EE7 A;  1P5S A;  1WYQ A;  1MB8 A;  2YRN A;  2EYI A;  1TJT A;  1WYM A;  1WYR A;  4TXI A;  4EDM A;  2WA6 A;  1RT8 A;  2JV9 A;  3FER A;  3HOR A;  1VKA A;  5A36 A;  2K2R A;  1BKR A;  4Q58 A;  2VZC A;  1WYP A;  2R0O A;  2WA5 A;  5A37 A; 
#chains in the Genus database with same CATH topology
 1DXX A;  3JAL M;  1SH6 A;  3KMW B;  5L0O A;  3HOP A;  2WFN A;  3JAR M;  2WDT A;  1WKU A;  2IGP A;  2EYN A;  1PXY A;  2D87 A;  1WYN A;  5A38 A;  1WYO A;  3KMU B;  4Q59 A;  4EDL A;  2L3G A;  2E9K A;  4DDP A;  1V5K A;  2K3S A;  2WE6 A;  2VZI B;  1AA2 A;  2HKP A;  1EUV A;  2VZG B;  4B7L A;  2R8U A;  3I6X A;  1AOA A;  4Q57 B;  3EAY A;  1P2X A;  1SH5 A;  4TXK A;  2QJX A;  5BVR A;  4LVP A;  1QAG A;  5FMT A;  3HOC A;  1UJO A;  2D89 A;  3CO1 A;  2WA7 A;  1H67 A;  2QJZ A;  2VE7 C;  5A4B A;  3F7P A;  2D88 A;  2RR8 A;  1BHD A;  4EDN A;  1WIX A;  2DK9 A;  5J8E A;  2D86 A;  1WYL A;  2VZD A;  2HL8 A;  3JAK M;  1WJO A;  3REP B;  2D85 A;  1UEG A;  1PA7 A;  3VP7 A;  3KY9 A;  2EE7 A;  1P5S A;  1WYQ A;  1MB8 A;  4LVR A;  2YRN A;  2EYI A;  1TJT A;  2HL9 A;  1WYM A;  1WYR A;  4TXI A;  4EDM A;  2WA6 A;  1RT8 A;  2JV9 A;  3FER A;  3HOR A;  1VKA A;  5A36 A;  2K2R A;  1BKR A;  4Q58 A;  2VE7 A;  5FMU A;  2VZC A;  2EQO A;  1WYP A;  2R0O A;  2WA5 A;  5A37 A; 
#chains in the Genus database with same CATH homology
 1DXX A;  3JAL M;  1SH6 A;  3KMW B;  5L0O A;  3HOP A;  2WFN A;  3JAR M;  1WKU A;  2EYN A;  1PXY A;  2D87 A;  1WYN A;  5A38 A;  1WYO A;  3KMU B;  4Q59 A;  4EDL A;  2L3G A;  2E9K A;  1V5K A;  2K3S A;  2VZI B;  1AA2 A;  2VZG B;  4B7L A;  2R8U A;  3I6X A;  1AOA A;  4Q57 B;  1P2X A;  1SH5 A;  4TXK A;  2QJX A;  5BVR A;  1QAG A;  3HOC A;  1UJO A;  2D89 A;  3CO1 A;  2WA7 A;  1H67 A;  2QJZ A;  5A4B A;  3F7P A;  2D88 A;  2RR8 A;  1BHD A;  4EDN A;  1WIX A;  2DK9 A;  5J8E A;  2D86 A;  1WYL A;  2VZD A;  3JAK M;  1WJO A;  3REP B;  2D85 A;  1UEG A;  1PA7 A;  3KY9 A;  2EE7 A;  1P5S A;  1WYQ A;  1MB8 A;  2YRN A;  2EYI A;  1TJT A;  1WYM A;  1WYR A;  4TXI A;  4EDM A;  2WA6 A;  1RT8 A;  2JV9 A;  3FER A;  3HOR A;  1VKA A;  5A36 A;  2K2R A;  1BKR A;  4Q58 A;  2VZC A;  1WYP A;  2R0O A;  2WA5 A;  5A37 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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