3KMWB

Crystal structure of the ilk/alpha-parvin core complex (mgatp)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
124
structure length
124
Chain Sequence
AFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Integrin-linked kinase
total genus 40
structure length 124
sequence length 124
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3kmwB00
5A4BA 1AA2A 4Q59A 2K3SA 3JARM 1MB8A 1WYNA 2WA7A 1SH5A 3FERA 2EYIA 2RR8A 2E9KA 1WKUA 2D87A 3JALM 2D89A 3I6XA 1BHDA 4Q57B 4TXKA 1WYMA 1RT8A 2YRNA 4EDMA 3HOCA 1WYRA 1BKRA 1WIXA 4EDNA 1UJOA 1WYQA 3KY9A 1SH6A 1PA7A 5A36A 3HORA 1P5SA 2WFNA 3F7PA 2D88A 1VKAA 1P2XA 2QJZA 2K2RA 1WJOA 4EDLA 5A37A 2VZCA 1AOAA 3KMUB 2VZDA 1H67A 2L3GA 3KMWB 3JAKM 2D86A 5A38A 1WYPA 2VZIB 5J8EA 2R8UA 4Q58A 2QJXA 3CO1A 1V5KA 2EYNA 1TJTA 1WYLA 1PXYA 4B7LA 2D85A 2JV9A 3HOPA 5BVRA 2VZGB 1UEGA 1DXXA 1WYOA 2R0OA 1QAGA 2DK9A 2EE7A 3REPB 5L0OA 4TXIA 2WA6A 2WA5A
chains in the Genus database with same CATH superfamily
5A4BA 1AA2A 2HL8A 4Q59A 4LVPA 2K3SA 5FMUA 3JARM 1MB8A 2HL9A 1WYNA 2WA7A 1SH5A 3FERA 2WE6A 2EYIA 2RR8A 2E9KA 1WKUA 2D87A 3JALM 2D89A 5FMTA 3I6XA 1BHDA 4Q57B 4TXKA 1WYMA 1RT8A 2YRNA 4EDMA 3HOCA 1WYRA 1BKRA 1WIXA 4EDNA 1UJOA 4LVRA 1WYQA 3KY9A 1SH6A 1PA7A 5A36A 3HORA 1P5SA 2WFNA 3F7PA 2D88A 4DDPA 1VKAA 1P2XA 2QJZA 2K2RA 2VE7A 1WJOA 3EAYA 4EDLA 5A37A 2VZCA 1AOAA 3KMUB 2VZDA 2WDTA 1H67A 2L3GA 3KMWB 3JAKM 2D86A 5A38A 1WYPA 2VZIB 5J8EA 2R8UA 4Q58A 2QJXA 3CO1A 1V5KA 2EYNA 1TJTA 2IGPA 3VP7A 1WYLA 1PXYA 4B7LA 2D85A 2JV9A 3HOPA 5BVRA 2VZGB 2VE7C 1UEGA 1DXXA 1WYOA 2R0OA 1EUVA 1QAGA 2DK9A 2EE7A 3REPB 5L0OA 2EQOA 4TXIA 2HKPA 2WA6A 2WA5A
chains in the Genus database with same CATH topology
5A4BA 1AA2A 4Q59A 2K3SA 3JARM 1MB8A 1WYNA 2WA7A 1SH5A 3FERA 2EYIA 2RR8A 2E9KA 1WKUA 2D87A 3JALM 2D89A 3I6XA 1BHDA 4Q57B 4TXKA 1WYMA 1RT8A 2YRNA 4EDMA 3HOCA 1WYRA 1BKRA 1WIXA 4EDNA 1UJOA 1WYQA 3KY9A 1SH6A 1PA7A 5A36A 3HORA 1P5SA 2WFNA 3F7PA 2D88A 1VKAA 1P2XA 2QJZA 2K2RA 1WJOA 4EDLA 5A37A 2VZCA 1AOAA 3KMUB 2VZDA 1H67A 2L3GA 3KMWB 3JAKM 2D86A 5A38A 1WYPA 2VZIB 5J8EA 2R8UA 4Q58A 2QJXA 3CO1A 1V5KA 2EYNA 1TJTA 1WYLA 1PXYA 4B7LA 2D85A 2JV9A 3HOPA 5BVRA 2VZGB 1UEGA 1DXXA 1WYOA 2R0OA 1QAGA 2DK9A 2EE7A 3REPB 5L0OA 4TXIA 2WA6A 2WA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A4B A;  1AA2 A;  4Q59 A;  2K3S A;  3JAR M;  1MB8 A;  1WYN A;  2WA7 A;  1SH5 A;  3FER A;  2EYI A;  2RR8 A;  2E9K A;  1WKU A;  2D87 A;  3JAL M;  2D89 A;  3I6X A;  1BHD A;  4Q57 B;  4TXK A;  1WYM A;  1RT8 A;  2YRN A;  4EDM A;  3HOC A;  1WYR A;  1BKR A;  1WIX A;  4EDN A;  1UJO A;  1WYQ A;  3KY9 A;  1SH6 A;  1PA7 A;  5A36 A;  3HOR A;  1P5S A;  2WFN A;  3F7P A;  2D88 A;  1VKA A;  1P2X A;  2QJZ A;  2K2R A;  1WJO A;  4EDL A;  5A37 A;  2VZC A;  1AOA A;  3KMU B;  2VZD A;  1H67 A;  2L3G A;  3KMW B;  3JAK M;  2D86 A;  5A38 A;  1WYP A;  2VZI B;  5J8E A;  2R8U A;  4Q58 A;  2QJX A;  3CO1 A;  1V5K A;  2EYN A;  1TJT A;  1WYL A;  1PXY A;  4B7L A;  2D85 A;  2JV9 A;  3HOP A;  5BVR A;  2VZG B;  1UEG A;  1DXX A;  1WYO A;  2R0O A;  1QAG A;  2DK9 A;  2EE7 A;  3REP B;  5L0O A;  4TXI A;  2WA6 A;  2WA5 A; 
#chains in the Genus database with same CATH topology
 5A4B A;  1AA2 A;  2HL8 A;  4Q59 A;  4LVP A;  2K3S A;  5FMU A;  3JAR M;  1MB8 A;  2HL9 A;  1WYN A;  2WA7 A;  1SH5 A;  3FER A;  2WE6 A;  2EYI A;  2RR8 A;  2E9K A;  1WKU A;  2D87 A;  3JAL M;  2D89 A;  5FMT A;  3I6X A;  1BHD A;  4Q57 B;  4TXK A;  1WYM A;  1RT8 A;  2YRN A;  4EDM A;  3HOC A;  1WYR A;  1BKR A;  1WIX A;  4EDN A;  1UJO A;  4LVR A;  1WYQ A;  3KY9 A;  1SH6 A;  1PA7 A;  5A36 A;  3HOR A;  1P5S A;  2WFN A;  3F7P A;  2D88 A;  4DDP A;  1VKA A;  1P2X A;  2QJZ A;  2K2R A;  2VE7 A;  1WJO A;  3EAY A;  4EDL A;  5A37 A;  2VZC A;  1AOA A;  3KMU B;  2VZD A;  2WDT A;  1H67 A;  2L3G A;  3KMW B;  3JAK M;  2D86 A;  5A38 A;  1WYP A;  2VZI B;  5J8E A;  2R8U A;  4Q58 A;  2QJX A;  3CO1 A;  1V5K A;  2EYN A;  1TJT A;  2IGP A;  3VP7 A;  1WYL A;  1PXY A;  4B7L A;  2D85 A;  2JV9 A;  3HOP A;  5BVR A;  2VZG B;  2VE7 C;  1UEG A;  1DXX A;  1WYO A;  2R0O A;  1EUV A;  1QAG A;  2DK9 A;  2EE7 A;  3REP B;  5L0O A;  2EQO A;  4TXI A;  2HKP A;  2WA6 A;  2WA5 A; 
#chains in the Genus database with same CATH homology
 5A4B A;  1AA2 A;  4Q59 A;  2K3S A;  3JAR M;  1MB8 A;  1WYN A;  2WA7 A;  1SH5 A;  3FER A;  2EYI A;  2RR8 A;  2E9K A;  1WKU A;  2D87 A;  3JAL M;  2D89 A;  3I6X A;  1BHD A;  4Q57 B;  4TXK A;  1WYM A;  1RT8 A;  2YRN A;  4EDM A;  3HOC A;  1WYR A;  1BKR A;  1WIX A;  4EDN A;  1UJO A;  1WYQ A;  3KY9 A;  1SH6 A;  1PA7 A;  5A36 A;  3HOR A;  1P5S A;  2WFN A;  3F7P A;  2D88 A;  1VKA A;  1P2X A;  2QJZ A;  2K2R A;  1WJO A;  4EDL A;  5A37 A;  2VZC A;  1AOA A;  3KMU B;  2VZD A;  1H67 A;  2L3G A;  3KMW B;  3JAK M;  2D86 A;  5A38 A;  1WYP A;  2VZI B;  5J8E A;  2R8U A;  4Q58 A;  2QJX A;  3CO1 A;  1V5K A;  2EYN A;  1TJT A;  1WYL A;  1PXY A;  4B7L A;  2D85 A;  2JV9 A;  3HOP A;  5BVR A;  2VZG B;  1UEG A;  1DXX A;  1WYO A;  2R0O A;  1QAG A;  2DK9 A;  2EE7 A;  3REP B;  5L0O A;  4TXI A;  2WA6 A;  2WA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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