3KQDL

Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one
Total Genus 10
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
52
structure length
52
Chain Sequence
KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phenyltriazolinones as potent factor Xa inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords factor Xa heavy chain
total genus 10
structure length 52
sequence length 52
ec nomenclature ec 3.4.21.6: Coagulation factor Xa.
pdb deposition date 2009-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.25.10 Mainly Beta Ribbon Laminin Laminin 3kqdL00
4ISHL 1EGFA 1AUTL 1G1RA 1XKBA 3LN0A 3TGFA 2NPRA 4X8UL 1APQA 1ATEA 3ASIA 3OLTA 1FFMA 1XKAL 4CUEA 2J38B 2I9BA 2P26A 2VWOL 1PRHA 2Y81B 2Y7XB 4O1ZA 1ZAQA 2P16L 2XBWL 4Y6DB 3ZYIB 1KLIL 2BQWA 2FZZL 4D0FA 3NJPC 1HT5A 1KSNB 3HS7A 3N8WB 2GD4A 2KL7A 2WYJB 1Z6EL 1CCVA 3KQBL 3HO3A 1OB1C 2UWLB 4Y79B 5JBCE 5FDQA 2PR3B 2J4IB 4RRXA 1APOA 2H9EL 3F6UL 1EPJA 3LTFB 3CENL 1HRFA 3NT1A 2WPHE 3GCXE 2PHBB 2WG3C 3Q3KB 2YGPA 1UZKA 5L30L 1FAXL 1G1QA 2WPLE 4MMZB 2K2TA 2FLBL 1HT8A 4BTUA 5JVZA 5KN5C 1IOXA 4RRWA 3SOQA 1U67A 4PH9A 1RFNB 4NA9L 2BMGA 3HO5A 3M36L 3V65B 4Z0LA 1UZPA 1HAFA 2W2NE 3U73A 1V3XB 1SZBA 4JZDL 2FLGA 3CA7A 4X8VL 4Z0KB 1PXXA 2UWOB 2XC5L 4M11A 5IKQA 2RA0L 2ADXA 3TK5B 4BXWA 4ZXXL 5JW1A 1XFEA 3R05A 5E8DA 2P3UA 2WG4B 4CUDA 2FD6A 1NFWB 5I46L 4AQTA 2VVVL 1QFKL 2MHPA 2OYEP 1EAIC 3MQEA 1IQML 2M74A 1P9JA 1BF9A 4XLWA 1FSBA 2UWPB 3TBDA 1G1TA 1K37A 1KLJL 1P0SL 1JV2B 5CKQA 1NFYB 2BO2A 2CJIB 1LQDA 2TGFA 1NFUB 2BOUA 1Q4GA 3KQDL 1M1XB 2Y82B 2W3IB 4M10A 2VH0B 1W8BL 2G00L 1L5GB 3NTGA 1ATAA 5COXA 1IQNL 2VVUL 1F0SB 4FM5A 3BT1A 2BOXA 1IJQA 1EMOA 4BTIA 3V64C 1IQKL 5JBAE 2WYGB 1CVWL 4JZEL 3BPSE 1B9WA 2WFTA 5IKTA 3LN1A 4LORA 2WPME 2J94B 4G1MB 2KB9A 1WHFA 1FE2A 4C16A 1N7DA 1A3PA 3CFWA 1HJ7A 3N8YA 3QMOA 2J34B 2W26B 4D90A 2VWNL 1IP0A 1EPHA 3RR3A 1CVUA 3KRKA 1DQBA 2XBVL 1YUKB 2I9AA 1HX2A 1F7EA 1IQFL 1IVOC 5CISA 2P3FN 1NT0A 1NPEB 2XC4L 4ZXYL 1HAEA 3QH0A 3ZYGA 1F0RB 2P3FL 1EBVA 3IITB 3KQCL 1ATDA 2XBXL 2P94L 3M37L 1UZQA 3HS6A 4ZHAB 3N8ZA 4ZH8B 2YGOA 2MGPA 3N8XA 2EI6B 1FJSL 3PGHA 1IQIL 1HCGB 1LPKA 1PFXL 1N1IA 1PTHA 1HREA 4TGFA 2W2QE 3KK6A 1FAKL 2WFXB 2EI8B 4LMFA 4MMYB 4JYUL 2VH6B 2Q1JB 1MQ5L 1J9CL 2J2UB 1CX2A 1YUFA 4COXA 4YT7L 4RRYA 2BOKL 1KIGL 3P5BL 1URKA 4RUTA 4MMXB 3F1SB 3POYA 1LMJA 2P93L 3GCWE 2D1JB 3Q7DA 3FFGL 3EGFA 2OYUP 3KQEL 1EPIA 1GK5A 1U8CB 2VWMK 3N8WA 2BQ7A 5CKNA 2XBYL 1DVAL 4NGAL 2BQ6A 1YO8A 2WPJE 2BOHA 4CUFA 4NG9L 5JVYA 2EI7B 3SOBB 1NQLB 1NFXB 4Y7AB 3TZIA 1G2LB 1UZJA 5KIRA 2P3TA 4Y71B 1TLEA 1ATBA 3N8YB 5JB9E 1XDTR 1FF7A 2MGRA 2WPKE 2WPIE 2AYLA 1F7MA 2P95L 5IKRA 3FBYA 4X8SL 1NZIA 2W2ME 3LTGD 1CEJA 4BDXA 3ELAL 2Y38A 3GISX 5F19A 2Y5GL 4JZFL 3OLUA 3LAQA 2RHPA 3HPTA 4Y76B 4OTJA 1EZQB 2PUQL 5F1AA 1DIYA 1LPGA 2F9BL 1W7XL 3SOVA 1EPGA 2B7DL 2Y7ZB 4X8TL 1COUA 1WHEA 1DX5I 1DDXA 3TH3L 2Y80B 4D0EA 5CKMA 1YUGA 5EGMB 2W2OE 3HO4A 1EQGA 4RS0A 1YGCL 2Y5HL 4BDWA 3FCSB 1LPZA 2Y5FL 1IOEL 2VVCK 3TK6B 1IQEL 1CCFA 1MQ6L 4YZUB 3LC3B 3KL6B 2W86A 1JBUL 2J95B 4BTTA 5JB8E 4Z6AL 1MOXC 1WU1B 2DDUA 4ZAEB 6COXA 1HZ8A 3U7UG 3MDLA 3LIWB 5L2ZL 4OTYA 4XL1A 2VJ3A 1IGXA 2KV4A 3SW2A 1Z6CA 2P28B 1KLOA 1PGEA 3IJEB 1IQGL 4ISIL 1IQLL 1EMNA 1G1SA 1L3YA 4Y7BB 1IQHL 1I0UA 4O02B 3ENSA 1K36A 5L2YL 1CQEA 1O5DL 3LC5B 2K2SB 3DEMA 4YT6L 1IGZA 5IKVA 2VWLL 3NTBA 4JYVL 3QCWA 1C5MF 3ZYJB 1TOZA 3H5CB 3K9XA 1G2MB 4XBMA 4BXSA 5JBBE 1ADXA 1EQHA 4A7IA 2FLRL 2BZ6L 2RNLA 2W3KB 4CSYA 3BT2A 1X7AL 3HS5A 2XC0L 1JL9A 1TPGA 2W2PE 4RRZA 4E1GA 3CS7L 3C9AC 3N8VA 3KCGL 1IQJL 5K0HB 2JKHL
chains in the Genus database with same CATH superfamily
4ISHL 1EGFA 1AUTL 1G1RA 1XKBA 3LN0A 3TGFA 2NPRA 4X8UL 1APQA 1ATEA 3ASIA 3OLTA 1FFMA 1XKAL 4CUEA 2J38B 2I9BA 2P26A 2VWOL 1PRHA 2Y81B 2Y7XB 4O1ZA 1ZAQA 2P16L 2XBWL 4Y6DB 3ZYIB 1KLIL 2BQWA 2KNIA 2FZZL 4D0FA 3NJPC 1HT5A 1V1HA 1KSNB 2YGQA 3HS7A 3N8WB 2GD4A 2KL7A 2WYJB 1Z6EL 1CCVA 3KQBL 3HO3A 1OB1C 2UWLB 4Y79B 5JBCE 5FDQA 2PR3B 2J4IB 4RRXA 1APOA 2H9EL 3F6UL 1EPJA 3LTFB 3CENL 1HRFA 3NT1A 2WPHE 3GCXE 2PHBB 2WG3C 3Q3KB 2YGPA 1UZKA 5L30L 1FAXL 1G1QA 2WPLE 2H9EC 4MMZB 2K2TA 2FLBL 1HT8A 4BTUA 5JVZA 5KN5C 1IOXA 4RRWA 3SOQA 1U67A 4PH9A 2WZPP 1RFNB 4NA9L 2BMGA 3HO5A 3M36L 3V65B 4Z0LA 1UZPA 1HAFA 2W2NE 3U73A 1LK9A 1V3XB 1SZBA 4JZDL 2FLGA 3CA7A 4X8VL 4Z0KB 1PXXA 2UWOB 2XC5L 4M11A 5IKQA 2RA0L 2ADXA 3TK5B 4BXWA 4ZXXL 5JW1A 1LMMA 1KKEA 1XFEA 3R05A 5E8DA 2P3UA 2WG4B 4CUDA 2FD6A 1NFWB 5I46L 4AQTA 2VVVL 1QFKL 2MHPA 2OYEP 2JJLA 1EAIC 2VRSA 3MQEA 1IQML 2M74A 1P9JA 1BF9A 4XLWA 1FSBA 2UWPB 3TBDA 1G1TA 1K37A 1KLJL 1P0SL 1JV2B 5CKQA 1NFYB 2BO2A 2CJIB 1LQDA 2TGFA 1NFUB 2BOUA 1Q4GA 3KQDL 1M1XB 2Y82B 2W3IB 4M10A 2VH0B 1W8BL 2G00L 1L5GB 3NTGA 1ATAA 5COXA 1IQNL 2VVUL 1F0SB 4FM5A 3BT1A 2BOXA 1IJQA 1EMOA 4BTIA 3V64C 1IQKL 5JBAE 2WYGB 1CVWL 4JZEL 3BPSE 1B9WA 2WFTA 5IKTA 3LN1A 4LORA 2WPME 2J94B 4G1MB 2KB9A 1WHFA 1FE2A 4C16A 1N7DA 1A3PA 3CFWA 1HJ7A 3N8YA 3QMOA 2J34B 2W26B 4D90A 2VWNL 1IP0A 1EPHA 3RR3A 1CVUA 3KRKA 1DQBA 2XBVL 1YUKB 2I9AA 1HX2A 1F7EA 1IQFL 1IVOC 5CISA 2P3FN 1NT0A 2HOXA 1NPEB 2XC4L 4ZXYL 1HAEA 3QH0A 3ZYGA 1F0RB 2P3FL 1EBVA 3IITB 3KQCL 1ATDA 2XBXL 2P94L 3M37L 1QIUA 1UZQA 3HS6A 4ZHAB 3N8ZA 4ZH8B 2YGOA 2MGPA 3N8XA 2EI6B 1FJSL 3PGHA 1IQIL 1HCGB 1LPKA 1PFXL 1N1IA 1PTHA 1HREA 4TGFA 2W2QE 3KK6A 1FAKL 2WFXB 2EI8B 4LMFA 4MMYB 4JYUL 2VH6B 2Q1JB 1MQ5L 1J9CL 2J2UB 1CX2A 1YUFA 4COXA 4YT7L 4RRYA 2BOKL 1KIGL 3P5BL 1URKA 4RUTA 4MMXB 3F1SB 3POYA 1LMJA 2P93L 3GCWE 2D1JB 3Q7DA 3FFGL 3EGFA 2OYUP 3KQEL 1EPIA 1GK5A 1U8CB 2VWMK 3N8WA 2BQ7A 5CKNA 2XBYL 1DVAL 4NGAL 2BQ6A 1YO8A 2WPJE 2BOHA 4CUFA 4NG9L 5JVYA 2EI7B 3SOBB 1NQLB 1NFXB 4Y7AB 3TZIA 1G2LB 1UZJA 5KIRA 4GU3A 2P3TA 4Y71B 1TLEA 1ATBA 3N8YB 5JB9E 1XDTR 1FF7A 2MGRA 2WPKE 2WPIE 2AYLA 1F7MA 2P95L 5IKRA 3FBYA 4X8SL 1NZIA 2W2ME 3LTGD 1CEJA 4BDXA 3ELAL 2Y38A 3GISX 5F19A 2Y5GL 4JZFL 2BT7A 3OLUA 3LAQA 2RHPA 4GU4A 3HPTA 4Y76B 4OTJA 1EZQB 1V1IA 2PUQL 5F1AA 1DIYA 1LPGA 2F9BL 1W7XL 3SOVA 1EPGA 2B7DL 2Y7ZB 4X8TL 1COUA 1WHEA 1DX5I 1DDXA 3TH3L 2Y80B 4D0EA 5CKMA 1YUGA 5EGMB 2W2OE 3HO4A 1EQGA 4RS0A 1YGCL 2Y5HL 4BDWA 3FCSB 1LPZA 2HORA 2Y5FL 1IOEL 2VVCK 3TK6B 1IQEL 1CCFA 1MQ6L 4YZUB 3LC3B 3KL6B 2W86A 1JBUL 2J95B 4BTTA 5JB8E 4Z6AL 1MOXC 1WU1B 2DDUA 4ZAEB 6COXA 1HZ8A 3U7UG 3MDLA 3LIWB 5L2ZL 4OTYA 4XL1A 2VJ3A 1IGXA 2KV4A 3SW2A 1Z6CA 2P28B 1KLOA 1PGEA 3IJEB 1IQGL 2BSFA 1IQLL 4ISIL 1EMNA 1G1SA 1L3YA 4Y7BB 1IQHL 1I0UA 4O02B 3ENSA 1K36A 5L2YL 1CQEA 1O5DL 3LC5B 4A94C 2K2SB 3DEMA 4YT6L 1IGZA 5IKVA 2VWLL 3NTBA 4JYVL 3QCWA 1C5MF 3S6XA 3ZYJB 1TOZA 2BT8A 3H5CB 3K9XA 1G2MB 4XBMA 4BXSA 5JBBE 1ADXA 1EQHA 4A7IA 2FLRL 2BZ6L 2RNLA 2W3KB 4CSYA 3BT2A 1X7AL 3HS5A 2XC0L 1JL9A 1TPGA 2W2PE 4RRZA 4E1GA 3CS7L 3C9AC 3N8VA 3KCGL 1IQJL 5K0HB 2JKHL
chains in the Genus database with same CATH topology
4ISHL 1EGFA 1AUTL 1G1RA 1XKBA 3LN0A 3TGFA 2NPRA 4X8UL 1APQA 1ATEA 3ASIA 3OLTA 1FFMA 1XKAL 4CUEA 2J38B 2I9BA 2P26A 2VWOL 1PRHA 2Y81B 2Y7XB 4O1ZA 1ZAQA 2P16L 2XBWL 4Y6DB 3ZYIB 1KLIL 2BQWA 2KNIA 2FZZL 4D0FA 3NJPC 1HT5A 1KSNB 2YGQA 3HS7A 3N8WB 2GD4A 2KL7A 2WYJB 1Z6EL 1CCVA 3KQBL 3HO3A 1OB1C 2UWLB 4Y79B 5JBCE 5FDQA 2PR3B 2J4IB 4RRXA 1APOA 2H9EL 3F6UL 1EPJA 3LTFB 3CENL 1HRFA 3NT1A 2WPHE 3GCXE 2PHBB 2WG3C 3Q3KB 2YGPA 1UZKA 5L30L 1FAXL 1G1QA 2WPLE 2H9EC 4MMZB 2K2TA 2FLBL 1HT8A 4BTUA 5JVZA 5KN5C 1IOXA 4RRWA 3SOQA 1U67A 4PH9A 2WZPP 1RFNB 4NA9L 2BMGA 3HO5A 3M36L 3V65B 4Z0LA 1UZPA 1HAFA 2W2NE 3U73A 1V3XB 1SZBA 4JZDL 2FLGA 3CA7A 4X8VL 4Z0KB 1PXXA 2UWOB 2XC5L 4M11A 5IKQA 2RA0L 2ADXA 3TK5B 4BXWA 4ZXXL 5JW1A 1LMMA 1XFEA 3R05A 5E8DA 2P3UA 2WG4B 4CUDA 2FD6A 1NFWB 5I46L 4AQTA 2VVVL 1QFKL 2MHPA 2OYEP 1EAIC 3MQEA 1IQML 2M74A 1P9JA 1BF9A 4XLWA 1FSBA 2UWPB 3TBDA 1G1TA 1K37A 1KLJL 1P0SL 1JV2B 5CKQA 1NFYB 2BO2A 2CJIB 1LQDA 2TGFA 1NFUB 2BOUA 1Q4GA 3KQDL 1M1XB 2Y82B 2W3IB 4M10A 2VH0B 1W8BL 2G00L 1L5GB 3NTGA 1ATAA 5COXA 1IQNL 2VVUL 1F0SB 4FM5A 3BT1A 2BOXA 1IJQA 1EMOA 4BTIA 3V64C 1IQKL 5JBAE 2WYGB 1CVWL 4JZEL 3BPSE 1B9WA 2WFTA 5IKTA 3LN1A 4LORA 2WPME 2J94B 4G1MB 2KB9A 1WHFA 1FE2A 4C16A 1N7DA 1A3PA 3CFWA 1HJ7A 3N8YA 3QMOA 2J34B 2W26B 4D90A 2VWNL 1IP0A 1EPHA 3RR3A 1CVUA 3KRKA 1DQBA 2XBVL 1YUKB 2I9AA 1HX2A 1F7EA 1IQFL 1IVOC 5CISA 2P3FN 1NT0A 1NPEB 2XC4L 4ZXYL 1HAEA 3QH0A 3ZYGA 1F0RB 2P3FL 1EBVA 3IITB 3KQCL 1ATDA 2XBXL 2P94L 3M37L 1UZQA 3HS6A 4ZHAB 3N8ZA 4ZH8B 2YGOA 2MGPA 3N8XA 2EI6B 1FJSL 3PGHA 1IQIL 1HCGB 1LPKA 1PFXL 1N1IA 1PTHA 1HREA 4TGFA 2W2QE 3KK6A 1FAKL 2WFXB 2EI8B 4LMFA 4MMYB 4JYUL 2VH6B 2Q1JB 1MQ5L 1J9CL 2J2UB 1CX2A 1YUFA 4COXA 4YT7L 4RRYA 2BOKL 1KIGL 3P5BL 1URKA 4RUTA 4MMXB 3F1SB 3POYA 1LMJA 2P93L 3GCWE 2D1JB 3Q7DA 3FFGL 3EGFA 2OYUP 3KQEL 1EPIA 1GK5A 1U8CB 2VWMK 3N8WA 2BQ7A 5CKNA 2XBYL 1DVAL 4NGAL 2BQ6A 1YO8A 2WPJE 2BOHA 4CUFA 4NG9L 5JVYA 2EI7B 3SOBB 1NQLB 1NFXB 4Y7AB 3TZIA 1G2LB 1UZJA 5KIRA 2P3TA 4Y71B 1TLEA 1ATBA 3N8YB 5JB9E 1XDTR 1FF7A 2MGRA 2WPKE 2WPIE 2AYLA 1F7MA 2P95L 5IKRA 3FBYA 4X8SL 1NZIA 2W2ME 3LTGD 1CEJA 4BDXA 3ELAL 2Y38A 3GISX 5F19A 2Y5GL 4JZFL 3OLUA 3LAQA 2RHPA 3HPTA 4Y76B 4OTJA 1EZQB 2PUQL 5F1AA 1DIYA 1LPGA 2F9BL 1W7XL 3SOVA 1EPGA 2B7DL 2Y7ZB 4X8TL 1COUA 1WHEA 1DX5I 1DDXA 3TH3L 2Y80B 4D0EA 5CKMA 1YUGA 5EGMB 2W2OE 3HO4A 1EQGA 4RS0A 1YGCL 2Y5HL 4BDWA 3FCSB 1LPZA 2Y5FL 1IOEL 2VVCK 3TK6B 1IQEL 1CCFA 1MQ6L 4YZUB 3LC3B 3KL6B 2W86A 1JBUL 2J95B 4BTTA 5JB8E 4Z6AL 1MOXC 1WU1B 2DDUA 4ZAEB 6COXA 1HZ8A 3U7UG 3MDLA 3LIWB 5L2ZL 4OTYA 4XL1A 2VJ3A 1IGXA 2KV4A 3SW2A 1Z6CA 2P28B 1KLOA 1PGEA 3IJEB 1IQGL 4ISIL 1IQLL 1EMNA 1G1SA 1L3YA 4Y7BB 1IQHL 1I0UA 4O02B 3ENSA 1K36A 5L2YL 1CQEA 1O5DL 3LC5B 4A94C 2K2SB 3DEMA 4YT6L 1IGZA 5IKVA 2VWLL 3NTBA 4JYVL 3QCWA 1C5MF 3S6XA 3ZYJB 1TOZA 3H5CB 3K9XA 1G2MB 4XBMA 4BXSA 5JBBE 1ADXA 1EQHA 4A7IA 2FLRL 2BZ6L 2RNLA 2W3KB 4CSYA 3BT2A 1X7AL 3HS5A 2XC0L 1JL9A 1TPGA 2W2PE 4RRZA 4E1GA 3CS7L 3C9AC 3N8VA 3KCGL 1IQJL 5K0HB 2JKHL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ISH L;  1EGF A;  1AUT L;  1G1R A;  1XKB A;  3LN0 A;  3TGF A;  2NPR A;  4X8U L;  1APQ A;  1ATE A;  3ASI A;  3OLT A;  1FFM A;  1XKA L;  4CUE A;  2J38 B;  2I9B A;  2P26 A;  2VWO L;  1PRH A;  2Y81 B;  2Y7X B;  4O1Z A;  1ZAQ A;  2P16 L;  2XBW L;  4Y6D B;  3ZYI B;  1KLI L;  2BQW A;  2FZZ L;  4D0F A;  3NJP C;  1HT5 A;  1KSN B;  3HS7 A;  3N8W B;  2GD4 A;  2KL7 A;  2WYJ B;  1Z6E L;  1CCV A;  3KQB L;  3HO3 A;  1OB1 C;  2UWL B;  4Y79 B;  5JBC E;  5FDQ A;  2PR3 B;  2J4I B;  4RRX A;  1APO A;  2H9E L;  3F6U L;  1EPJ A;  3LTF B;  3CEN L;  1HRF A;  3NT1 A;  2WPH E;  3GCX E;  2PHB B;  2WG3 C;  3Q3K B;  2YGP A;  1UZK A;  5L30 L;  1FAX L;  1G1Q A;  2WPL E;  4MMZ B;  2K2T A;  2FLB L;  1HT8 A;  4BTU A;  5JVZ A;  5KN5 C;  1IOX A;  4RRW A;  3SOQ A;  1U67 A;  4PH9 A;  1RFN B;  4NA9 L;  2BMG A;  3HO5 A;  3M36 L;  3V65 B;  4Z0L A;  1UZP A;  1HAF A;  2W2N E;  3U73 A;  1V3X B;  1SZB A;  4JZD L;  2FLG A;  3CA7 A;  4X8V L;  4Z0K B;  1PXX A;  2UWO B;  2XC5 L;  4M11 A;  5IKQ A;  2RA0 L;  2ADX A;  3TK5 B;  4BXW A;  4ZXX L;  5JW1 A;  1XFE A;  3R05 A;  5E8D A;  2P3U A;  2WG4 B;  4CUD A;  2FD6 A;  1NFW B;  5I46 L;  4AQT A;  2VVV L;  1QFK L;  2MHP A;  2OYE P;  1EAI C;  3MQE A;  1IQM L;  2M74 A;  1P9J A;  1BF9 A;  4XLW A;  1FSB A;  2UWP B;  3TBD A;  1G1T A;  1K37 A;  1KLJ L;  1P0S L;  1JV2 B;  5CKQ A;  1NFY B;  2BO2 A;  2CJI B;  1LQD A;  2TGF A;  1NFU B;  2BOU A;  1Q4G A;  3KQD L;  1M1X B;  2Y82 B;  2W3I B;  4M10 A;  2VH0 B;  1W8B L;  2G00 L;  1L5G B;  3NTG A;  1ATA A;  5COX A;  1IQN L;  2VVU L;  1F0S B;  4FM5 A;  3BT1 A;  2BOX A;  1IJQ A;  1EMO A;  4BTI A;  3V64 C;  1IQK L;  5JBA E;  2WYG B;  1CVW L;  4JZE L;  3BPS E;  1B9W A;  2WFT A;  5IKT A;  3LN1 A;  4LOR A;  2WPM E;  2J94 B;  4G1M B;  2KB9 A;  1WHF A;  1FE2 A;  4C16 A;  1N7D A;  1A3P A;  3CFW A;  1HJ7 A;  3N8Y A;  3QMO A;  2J34 B;  2W26 B;  4D90 A;  2VWN L;  1IP0 A;  1EPH A;  3RR3 A;  1CVU A;  3KRK A;  1DQB A;  2XBV L;  1YUK B;  2I9A A;  1HX2 A;  1F7E A;  1IQF L;  1IVO C;  5CIS A;  2P3F N;  1NT0 A;  1NPE B;  2XC4 L;  4ZXY L;  1HAE A;  3QH0 A;  3ZYG A;  1F0R B;  2P3F L;  1EBV A;  3IIT B;  3KQC L;  1ATD A;  2XBX L;  2P94 L;  3M37 L;  1UZQ A;  3HS6 A;  4ZHA B;  3N8Z A;  4ZH8 B;  2YGO A;  2MGP A;  3N8X A;  2EI6 B;  1FJS L;  3PGH A;  1IQI L;  1HCG B;  1LPK A;  1PFX L;  1N1I A;  1PTH A;  1HRE A;  4TGF A;  2W2Q E;  3KK6 A;  1FAK L;  2WFX B;  2EI8 B;  4LMF A;  4MMY B;  4JYU L;  2VH6 B;  2Q1J B;  1MQ5 L;  1J9C L;  2J2U B;  1CX2 A;  1YUF A;  4COX A;  4YT7 L;  4RRY A;  2BOK L;  1KIG L;  3P5B L;  1URK A;  4RUT A;  4MMX B;  3F1S B;  3POY A;  1LMJ A;  2P93 L;  3GCW E;  2D1J B;  3Q7D A;  3FFG L;  3EGF A;  2OYU P;  3KQE L;  1EPI A;  1GK5 A;  1U8C B;  2VWM K;  3N8W A;  2BQ7 A;  5CKN A;  2XBY L;  1DVA L;  4NGA L;  2BQ6 A;  1YO8 A;  2WPJ E;  2BOH A;  4CUF A;  4NG9 L;  5JVY A;  2EI7 B;  3SOB B;  1NQL B;  1NFX B;  4Y7A B;  3TZI A;  1G2L B;  1UZJ A;  5KIR A;  2P3T A;  4Y71 B;  1TLE A;  1ATB A;  3N8Y B;  5JB9 E;  1XDT R;  1FF7 A;  2MGR A;  2WPK E;  2WPI E;  2AYL A;  1F7M A;  2P95 L;  5IKR A;  3FBY A;  4X8S L;  1NZI A;  2W2M E;  3LTG D;  1CEJ A;  4BDX A;  3ELA L;  2Y38 A;  3GIS X;  5F19 A;  2Y5G L;  4JZF L;  3OLU A;  3LAQ A;  2RHP A;  3HPT A;  4Y76 B;  4OTJ A;  1EZQ B;  2PUQ L;  5F1A A;  1DIY A;  1LPG A;  2F9B L;  1W7X L;  3SOV A;  1EPG A;  2B7D L;  2Y7Z B;  4X8T L;  1COU A;  1WHE A;  1DX5 I;  1DDX A;  3TH3 L;  2Y80 B;  4D0E A;  5CKM A;  1YUG A;  5EGM B;  2W2O E;  3HO4 A;  1EQG A;  4RS0 A;  1YGC L;  2Y5H L;  4BDW A;  3FCS B;  1LPZ A;  2Y5F L;  1IOE L;  2VVC K;  3TK6 B;  1IQE L;  1CCF A;  1MQ6 L;  4YZU B;  3LC3 B;  3KL6 B;  2W86 A;  1JBU L;  2J95 B;  4BTT A;  5JB8 E;  4Z6A L;  1MOX C;  1WU1 B;  2DDU A;  4ZAE B;  6COX A;  1HZ8 A;  3U7U G;  3MDL A;  3LIW B;  5L2Z L;  4OTY A;  4XL1 A;  2VJ3 A;  1IGX A;  2KV4 A;  3SW2 A;  1Z6C A;  2P28 B;  1KLO A;  1PGE A;  3IJE B;  1IQG L;  4ISI L;  1IQL L;  1EMN A;  1G1S A;  1L3Y A;  4Y7B B;  1IQH L;  1I0U A;  4O02 B;  3ENS A;  1K36 A;  5L2Y L;  1CQE A;  1O5D L;  3LC5 B;  2K2S B;  3DEM A;  4YT6 L;  1IGZ A;  5IKV A;  2VWL L;  3NTB A;  4JYV L;  3QCW A;  1C5M F;  3ZYJ B;  1TOZ A;  3H5C B;  3K9X A;  1G2M B;  4XBM A;  4BXS A;  5JBB E;  1ADX A;  1EQH A;  4A7I A;  2FLR L;  2BZ6 L;  2RNL A;  2W3K B;  4CSY A;  3BT2 A;  1X7A L;  3HS5 A;  2XC0 L;  1JL9 A;  1TPG A;  2W2P E;  4RRZ A;  4E1G A;  3CS7 L;  3C9A C;  3N8V A;  3KCG L;  1IQJ L;  5K0H B;  2JKH L; 
#chains in the Genus database with same CATH topology
 4ISH L;  1EGF A;  1AUT L;  1G1R A;  1XKB A;  3LN0 A;  3TGF A;  2NPR A;  4X8U L;  1APQ A;  1ATE A;  3ASI A;  3OLT A;  1FFM A;  1XKA L;  4CUE A;  2J38 B;  2I9B A;  2P26 A;  2VWO L;  1PRH A;  2Y81 B;  2Y7X B;  4O1Z A;  1ZAQ A;  2P16 L;  2XBW L;  4Y6D B;  3ZYI B;  1KLI L;  2BQW A;  2KNI A;  2FZZ L;  4D0F A;  3NJP C;  1HT5 A;  1V1H A;  1KSN B;  2YGQ A;  3HS7 A;  3N8W B;  2GD4 A;  2KL7 A;  2WYJ B;  1Z6E L;  1CCV A;  3KQB L;  3HO3 A;  1OB1 C;  2UWL B;  4Y79 B;  5JBC E;  5FDQ A;  2PR3 B;  2J4I B;  4RRX A;  1APO A;  2H9E L;  3F6U L;  1EPJ A;  3LTF B;  3CEN L;  1HRF A;  3NT1 A;  2WPH E;  3GCX E;  2PHB B;  2WG3 C;  3Q3K B;  2YGP A;  1UZK A;  5L30 L;  1FAX L;  1G1Q A;  2WPL E;  2H9E C;  4MMZ B;  2K2T A;  2FLB L;  1HT8 A;  4BTU A;  5JVZ A;  5KN5 C;  1IOX A;  4RRW A;  3SOQ A;  1U67 A;  4PH9 A;  2WZP P;  1RFN B;  4NA9 L;  2BMG A;  3HO5 A;  3M36 L;  3V65 B;  4Z0L A;  1UZP A;  1HAF A;  2W2N E;  3U73 A;  1LK9 A;  1V3X B;  1SZB A;  4JZD L;  2FLG A;  3CA7 A;  4X8V L;  4Z0K B;  1PXX A;  2UWO B;  2XC5 L;  4M11 A;  5IKQ A;  2RA0 L;  2ADX A;  3TK5 B;  4BXW A;  4ZXX L;  5JW1 A;  1LMM A;  1KKE A;  1XFE A;  3R05 A;  5E8D A;  2P3U A;  2WG4 B;  4CUD A;  2FD6 A;  1NFW B;  5I46 L;  4AQT A;  2VVV L;  1QFK L;  2MHP A;  2OYE P;  2JJL A;  1EAI C;  2VRS A;  3MQE A;  1IQM L;  2M74 A;  1P9J A;  1BF9 A;  4XLW A;  1FSB A;  2UWP B;  3TBD A;  1G1T A;  1K37 A;  1KLJ L;  1P0S L;  1JV2 B;  5CKQ A;  1NFY B;  2BO2 A;  2CJI B;  1LQD A;  2TGF A;  1NFU B;  2BOU A;  1Q4G A;  3KQD L;  1M1X B;  2Y82 B;  2W3I B;  4M10 A;  2VH0 B;  1W8B L;  2G00 L;  1L5G B;  3NTG A;  1ATA A;  5COX A;  1IQN L;  2VVU L;  1F0S B;  4FM5 A;  3BT1 A;  2BOX A;  1IJQ A;  1EMO A;  4BTI A;  3V64 C;  1IQK L;  5JBA E;  2WYG B;  1CVW L;  4JZE L;  3BPS E;  1B9W A;  2WFT A;  5IKT A;  3LN1 A;  4LOR A;  2WPM E;  2J94 B;  4G1M B;  2KB9 A;  1WHF A;  1FE2 A;  4C16 A;  1N7D A;  1A3P A;  3CFW A;  1HJ7 A;  3N8Y A;  3QMO A;  2J34 B;  2W26 B;  4D90 A;  2VWN L;  1IP0 A;  1EPH A;  3RR3 A;  1CVU A;  3KRK A;  1DQB A;  2XBV L;  1YUK B;  2I9A A;  1HX2 A;  1F7E A;  1IQF L;  1IVO C;  5CIS A;  2P3F N;  1NT0 A;  2HOX A;  1NPE B;  2XC4 L;  4ZXY L;  1HAE A;  3QH0 A;  3ZYG A;  1F0R B;  2P3F L;  1EBV A;  3IIT B;  3KQC L;  1ATD A;  2XBX L;  2P94 L;  3M37 L;  1QIU A;  1UZQ A;  3HS6 A;  4ZHA B;  3N8Z A;  4ZH8 B;  2YGO A;  2MGP A;  3N8X A;  2EI6 B;  1FJS L;  3PGH A;  1IQI L;  1HCG B;  1LPK A;  1PFX L;  1N1I A;  1PTH A;  1HRE A;  4TGF A;  2W2Q E;  3KK6 A;  1FAK L;  2WFX B;  2EI8 B;  4LMF A;  4MMY B;  4JYU L;  2VH6 B;  2Q1J B;  1MQ5 L;  1J9C L;  2J2U B;  1CX2 A;  1YUF A;  4COX A;  4YT7 L;  4RRY A;  2BOK L;  1KIG L;  3P5B L;  1URK A;  4RUT A;  4MMX B;  3F1S B;  3POY A;  1LMJ A;  2P93 L;  3GCW E;  2D1J B;  3Q7D A;  3FFG L;  3EGF A;  2OYU P;  3KQE L;  1EPI A;  1GK5 A;  1U8C B;  2VWM K;  3N8W A;  2BQ7 A;  5CKN A;  2XBY L;  1DVA L;  4NGA L;  2BQ6 A;  1YO8 A;  2WPJ E;  2BOH A;  4CUF A;  4NG9 L;  5JVY A;  2EI7 B;  3SOB B;  1NQL B;  1NFX B;  4Y7A B;  3TZI A;  1G2L B;  1UZJ A;  5KIR A;  4GU3 A;  2P3T A;  4Y71 B;  1TLE A;  1ATB A;  3N8Y B;  5JB9 E;  1XDT R;  1FF7 A;  2MGR A;  2WPK E;  2WPI E;  2AYL A;  1F7M A;  2P95 L;  5IKR A;  3FBY A;  4X8S L;  1NZI A;  2W2M E;  3LTG D;  1CEJ A;  4BDX A;  3ELA L;  2Y38 A;  3GIS X;  5F19 A;  2Y5G L;  4JZF L;  2BT7 A;  3OLU A;  3LAQ A;  2RHP A;  4GU4 A;  3HPT A;  4Y76 B;  4OTJ A;  1EZQ B;  1V1I A;  2PUQ L;  5F1A A;  1DIY A;  1LPG A;  2F9B L;  1W7X L;  3SOV A;  1EPG A;  2B7D L;  2Y7Z B;  4X8T L;  1COU A;  1WHE A;  1DX5 I;  1DDX A;  3TH3 L;  2Y80 B;  4D0E A;  5CKM A;  1YUG A;  5EGM B;  2W2O E;  3HO4 A;  1EQG A;  4RS0 A;  1YGC L;  2Y5H L;  4BDW A;  3FCS B;  1LPZ A;  2HOR A;  2Y5F L;  1IOE L;  2VVC K;  3TK6 B;  1IQE L;  1CCF A;  1MQ6 L;  4YZU B;  3LC3 B;  3KL6 B;  2W86 A;  1JBU L;  2J95 B;  4BTT A;  5JB8 E;  4Z6A L;  1MOX C;  1WU1 B;  2DDU A;  4ZAE B;  6COX A;  1HZ8 A;  3U7U G;  3MDL A;  3LIW B;  5L2Z L;  4OTY A;  4XL1 A;  2VJ3 A;  1IGX A;  2KV4 A;  3SW2 A;  1Z6C A;  2P28 B;  1KLO A;  1PGE A;  3IJE B;  1IQG L;  2BSF A;  1IQL L;  4ISI L;  1EMN A;  1G1S A;  1L3Y A;  4Y7B B;  1IQH L;  1I0U A;  4O02 B;  3ENS A;  1K36 A;  5L2Y L;  1CQE A;  1O5D L;  3LC5 B;  4A94 C;  2K2S B;  3DEM A;  4YT6 L;  1IGZ A;  5IKV A;  2VWL L;  3NTB A;  4JYV L;  3QCW A;  1C5M F;  3S6X A;  3ZYJ B;  1TOZ A;  2BT8 A;  3H5C B;  3K9X A;  1G2M B;  4XBM A;  4BXS A;  5JBB E;  1ADX A;  1EQH A;  4A7I A;  2FLR L;  2BZ6 L;  2RNL A;  2W3K B;  4CSY A;  3BT2 A;  1X7A L;  3HS5 A;  2XC0 L;  1JL9 A;  1TPG A;  2W2P E;  4RRZ A;  4E1G A;  3CS7 L;  3C9A C;  3N8V A;  3KCG L;  1IQJ L;  5K0H B;  2JKH L; 
#chains in the Genus database with same CATH homology
 4ISH L;  1EGF A;  1AUT L;  1G1R A;  1XKB A;  3LN0 A;  3TGF A;  2NPR A;  4X8U L;  1APQ A;  1ATE A;  3ASI A;  3OLT A;  1FFM A;  1XKA L;  4CUE A;  2J38 B;  2I9B A;  2P26 A;  2VWO L;  1PRH A;  2Y81 B;  2Y7X B;  4O1Z A;  1ZAQ A;  2P16 L;  2XBW L;  4Y6D B;  3ZYI B;  1KLI L;  2BQW A;  2KNI A;  2FZZ L;  4D0F A;  3NJP C;  1HT5 A;  1KSN B;  2YGQ A;  3HS7 A;  3N8W B;  2GD4 A;  2KL7 A;  2WYJ B;  1Z6E L;  1CCV A;  3KQB L;  3HO3 A;  1OB1 C;  2UWL B;  4Y79 B;  5JBC E;  5FDQ A;  2PR3 B;  2J4I B;  4RRX A;  1APO A;  2H9E L;  3F6U L;  1EPJ A;  3LTF B;  3CEN L;  1HRF A;  3NT1 A;  2WPH E;  3GCX E;  2PHB B;  2WG3 C;  3Q3K B;  2YGP A;  1UZK A;  5L30 L;  1FAX L;  1G1Q A;  2WPL E;  2H9E C;  4MMZ B;  2K2T A;  2FLB L;  1HT8 A;  4BTU A;  5JVZ A;  5KN5 C;  1IOX A;  4RRW A;  3SOQ A;  1U67 A;  4PH9 A;  2WZP P;  1RFN B;  4NA9 L;  2BMG A;  3HO5 A;  3M36 L;  3V65 B;  4Z0L A;  1UZP A;  1HAF A;  2W2N E;  3U73 A;  1V3X B;  1SZB A;  4JZD L;  2FLG A;  3CA7 A;  4X8V L;  4Z0K B;  1PXX A;  2UWO B;  2XC5 L;  4M11 A;  5IKQ A;  2RA0 L;  2ADX A;  3TK5 B;  4BXW A;  4ZXX L;  5JW1 A;  1LMM A;  1XFE A;  3R05 A;  5E8D A;  2P3U A;  2WG4 B;  4CUD A;  2FD6 A;  1NFW B;  5I46 L;  4AQT A;  2VVV L;  1QFK L;  2MHP A;  2OYE P;  1EAI C;  3MQE A;  1IQM L;  2M74 A;  1P9J A;  1BF9 A;  4XLW A;  1FSB A;  2UWP B;  3TBD A;  1G1T A;  1K37 A;  1KLJ L;  1P0S L;  1JV2 B;  5CKQ A;  1NFY B;  2BO2 A;  2CJI B;  1LQD A;  2TGF A;  1NFU B;  2BOU A;  1Q4G A;  3KQD L;  1M1X B;  2Y82 B;  2W3I B;  4M10 A;  2VH0 B;  1W8B L;  2G00 L;  1L5G B;  3NTG A;  1ATA A;  5COX A;  1IQN L;  2VVU L;  1F0S B;  4FM5 A;  3BT1 A;  2BOX A;  1IJQ A;  1EMO A;  4BTI A;  3V64 C;  1IQK L;  5JBA E;  2WYG B;  1CVW L;  4JZE L;  3BPS E;  1B9W A;  2WFT A;  5IKT A;  3LN1 A;  4LOR A;  2WPM E;  2J94 B;  4G1M B;  2KB9 A;  1WHF A;  1FE2 A;  4C16 A;  1N7D A;  1A3P A;  3CFW A;  1HJ7 A;  3N8Y A;  3QMO A;  2J34 B;  2W26 B;  4D90 A;  2VWN L;  1IP0 A;  1EPH A;  3RR3 A;  1CVU A;  3KRK A;  1DQB A;  2XBV L;  1YUK B;  2I9A A;  1HX2 A;  1F7E A;  1IQF L;  1IVO C;  5CIS A;  2P3F N;  1NT0 A;  1NPE B;  2XC4 L;  4ZXY L;  1HAE A;  3QH0 A;  3ZYG A;  1F0R B;  2P3F L;  1EBV A;  3IIT B;  3KQC L;  1ATD A;  2XBX L;  2P94 L;  3M37 L;  1UZQ A;  3HS6 A;  4ZHA B;  3N8Z A;  4ZH8 B;  2YGO A;  2MGP A;  3N8X A;  2EI6 B;  1FJS L;  3PGH A;  1IQI L;  1HCG B;  1LPK A;  1PFX L;  1N1I A;  1PTH A;  1HRE A;  4TGF A;  2W2Q E;  3KK6 A;  1FAK L;  2WFX B;  2EI8 B;  4LMF A;  4MMY B;  4JYU L;  2VH6 B;  2Q1J B;  1MQ5 L;  1J9C L;  2J2U B;  1CX2 A;  1YUF A;  4COX A;  4YT7 L;  4RRY A;  2BOK L;  1KIG L;  3P5B L;  1URK A;  4RUT A;  4MMX B;  3F1S B;  3POY A;  1LMJ A;  2P93 L;  3GCW E;  2D1J B;  3Q7D A;  3FFG L;  3EGF A;  2OYU P;  3KQE L;  1EPI A;  1GK5 A;  1U8C B;  2VWM K;  3N8W A;  2BQ7 A;  5CKN A;  2XBY L;  1DVA L;  4NGA L;  2BQ6 A;  1YO8 A;  2WPJ E;  2BOH A;  4CUF A;  4NG9 L;  5JVY A;  2EI7 B;  3SOB B;  1NQL B;  1NFX B;  4Y7A B;  3TZI A;  1G2L B;  1UZJ A;  5KIR A;  2P3T A;  4Y71 B;  1TLE A;  1ATB A;  3N8Y B;  5JB9 E;  1XDT R;  1FF7 A;  2MGR A;  2WPK E;  2WPI E;  2AYL A;  1F7M A;  2P95 L;  5IKR A;  3FBY A;  4X8S L;  1NZI A;  2W2M E;  3LTG D;  1CEJ A;  4BDX A;  3ELA L;  2Y38 A;  3GIS X;  5F19 A;  2Y5G L;  4JZF L;  3OLU A;  3LAQ A;  2RHP A;  3HPT A;  4Y76 B;  4OTJ A;  1EZQ B;  2PUQ L;  5F1A A;  1DIY A;  1LPG A;  2F9B L;  1W7X L;  3SOV A;  1EPG A;  2B7D L;  2Y7Z B;  4X8T L;  1COU A;  1WHE A;  1DX5 I;  1DDX A;  3TH3 L;  2Y80 B;  4D0E A;  5CKM A;  1YUG A;  5EGM B;  2W2O E;  3HO4 A;  1EQG A;  4RS0 A;  1YGC L;  2Y5H L;  4BDW A;  3FCS B;  1LPZ A;  2Y5F L;  1IOE L;  2VVC K;  3TK6 B;  1IQE L;  1CCF A;  1MQ6 L;  4YZU B;  3LC3 B;  3KL6 B;  2W86 A;  1JBU L;  2J95 B;  4BTT A;  5JB8 E;  4Z6A L;  1MOX C;  1WU1 B;  2DDU A;  4ZAE B;  6COX A;  1HZ8 A;  3U7U G;  3MDL A;  3LIW B;  5L2Z L;  4OTY A;  4XL1 A;  2VJ3 A;  1IGX A;  2KV4 A;  3SW2 A;  1Z6C A;  2P28 B;  1KLO A;  1PGE A;  3IJE B;  1IQG L;  4ISI L;  1IQL L;  1EMN A;  1G1S A;  1L3Y A;  4Y7B B;  1IQH L;  1I0U A;  4O02 B;  3ENS A;  1K36 A;  5L2Y L;  1CQE A;  1O5D L;  3LC5 B;  4A94 C;  2K2S B;  3DEM A;  4YT6 L;  1IGZ A;  5IKV A;  2VWL L;  3NTB A;  4JYV L;  3QCW A;  1C5M F;  3S6X A;  3ZYJ B;  1TOZ A;  3H5C B;  3K9X A;  1G2M B;  4XBM A;  4BXS A;  5JBB E;  1ADX A;  1EQH A;  4A7I A;  2FLR L;  2BZ6 L;  2RNL A;  2W3K B;  4CSY A;  3BT2 A;  1X7A L;  3HS5 A;  2XC0 L;  1JL9 A;  1TPG A;  2W2P E;  4RRZ A;  4E1G A;  3CS7 L;  3C9A C;  3N8V A;  3KCG L;  1IQJ L;  5K0H B;  2JKH L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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