3KRXG

Human grk2 in complex with gbetgamma subunits and balanol (co-crystal)
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
60
structure length
60
Chain Sequence
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 13
structure length 60
sequence length 60
ec nomenclature
pdb deposition date 2009-11-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 3krxG00
2PBIA 1B9XB 3PVUG 5TDHG 1GP2G 5HE1G 1GG2G 1OMWG 5KDOG 2TRCG 3PSCG 3SN6G 1XHMB 5HE0G 5HE3G 5HE2G 3V5WG 1GOTG 3KRWG 4PNKG 4MK0G 2BCJG 1A0RG 3CIKG 3AH8G 3KRXG 1TBGE 1B9YB 3PVWG 4KFMG
chains in the Genus database with same CATH superfamily
2PBIA 1B9XB 3PVUG 5TDHG 1GP2G 5HE1G 1GG2G 1OMWG 5KDOG 2TRCG 1HFES 3PSCG 3SN6G 1XHMB 5HE0G 5HE3G 5HE2G 3V5WG 1GOTG 3KRWG 4PNKG 4MK0G 2BCJG 1A0RG 1IOJA 3CIKG 3AH8G 3KRXG 1TBGE 1B9YB 3PVWG 4KFMG
chains in the Genus database with same CATH topology
2PBIA 1B9XB 3PVUG 5TDHG 1GP2G 5HE1G 1GG2G 1OMWG 5KDOG 2TRCG 3PSCG 3SN6G 1XHMB 5HE0G 5HE3G 5HE2G 3V5WG 1GOTG 3KRWG 4PNKG 4MK0G 2BCJG 1A0RG 3CIKG 3AH8G 3KRXG 1TBGE 1B9YB 3PVWG 4KFMG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PBI A;  1B9X B;  3PVU G;  5TDH G;  1GP2 G;  5HE1 G;  1GG2 G;  1OMW G;  5KDO G;  2TRC G;  3PSC G;  3SN6 G;  1XHM B;  5HE0 G;  5HE3 G;  5HE2 G;  3V5W G;  1GOT G;  3KRW G;  4PNK G;  4MK0 G;  2BCJ G;  1A0R G;  3CIK G;  3AH8 G;  3KRX G;  1TBG E;  1B9Y B;  3PVW G;  4KFM G; 
#chains in the Genus database with same CATH topology
 2PBI A;  1B9X B;  3PVU G;  5TDH G;  1GP2 G;  5HE1 G;  1GG2 G;  1OMW G;  5KDO G;  2TRC G;  1HFE S;  3PSC G;  3SN6 G;  1XHM B;  5HE0 G;  5HE3 G;  5HE2 G;  3V5W G;  1GOT G;  3KRW G;  4PNK G;  4MK0 G;  2BCJ G;  1A0R G;  1IOJ A;  3CIK G;  3AH8 G;  3KRX G;  1TBG E;  1B9Y B;  3PVW G;  4KFM G; 
#chains in the Genus database with same CATH homology
 2PBI A;  1B9X B;  3PVU G;  5TDH G;  1GP2 G;  5HE1 G;  1GG2 G;  1OMW G;  5KDO G;  2TRC G;  3PSC G;  3SN6 G;  1XHM B;  5HE0 G;  5HE3 G;  5HE2 G;  3V5W G;  1GOT G;  3KRW G;  4PNK G;  4MK0 G;  2BCJ G;  1A0R G;  3CIK G;  3AH8 G;  3KRX G;  1TBG E;  1B9Y B;  3PVW G;  4KFM G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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