3KRYA

Crystal structure of mmp-13 in complex with sc-78080
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
164
structure length
164
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Collagenase 3
publication title Orally-active MMP-1 sparing alpha-tetrahydropyranyl and alpha-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 46
structure length 164
sequence length 164
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3kryA00
1GKCA 1YOUA 1UEAA 4H1QA 4H2EA 2X7MA 1BUDA 1ZTQA 1BUVM 4QKZA 2OW1A 2DW1A 2XS3A 1HY7A 1Y93A 1BSWA 1CGFA 1GKDA 1B8YA 3USNA 4J4MA 1R1JA 2W13A 5BOYA 1WNIA 3SHIA 3F1AA 3AYUA 4AUOA 4FXYP 1MMBA 1DTHA 1BM6A 1KUKA 1PWPA 1ND1A 3O64A 3GBOA 4WKEA 1QUAA 3I7GA 3ELMA 4HMAA 1BKCA 2OXWA 2X3BA 1JAPA 1JIWP 1UMTA 5D1SA 1FLSA 1HFCA 3WV1A 2W12A 1BQOA 4XBHA 2MLRA 1L6JA 4GR8A 1XFUA 3F15A 4AIGA 2OZRA 1ZXCA 3LJTA 2JIHA 1G49A 4WKIA 3BA0A 3OHLA 3DNGA 3HDAP 1D5JA 1Z3JA 2D1OA 1SRPA 3RTTA 4A7BA 1QIAA 3KHIA 4H49A 2O36A 1XUDA 4IJOA 5BOTA 3LK8A 4HX3A 2RJQA 4JA1A 4ILWD 3F16A 2DDYA 4PKQA 2D1NA 1EUBA 1JANA 1CGEA 1ASTA 1G12A 4PKSA 1JJ9A 1KUFA 3L0VA 5D2BA 1SLMA 1OM6A 2OXZA 1UTZA 3EHYA 2RJPA 5JMYA 1XFVA 5CXAA 830CA 5LABA 3KRYA 3LGPA 5D7WA 3EDGA 3LEAA 1G05A 1K7QA 2WO8A 3TS4A 2JNPA 1BKCE 1IAAA 3LUNA 3B8ZA 1D8MA 4H3XA 1O0TA 4GWMA 5I12A 1FM1A 2O3EA 5H8XA 1GE7A 3OHOA 1SU3A 2WOAA 2OY4A 3LJZA 5BPAA 2OI0A 1R55A 2CKIA 2PJTA 5CZMA 1BIWA 1AYKA 1JAOA 1CIZA 5CUHA 3HYGA 2OY2A 1I76A 3N2UA 4EFSA 1IAEA 2OXUA 3NX7A 4Q1LA 3HBUP 1C7KA 1HFSA 1JAQA 4PKUA 2KRJA 3B2ZA 2Z2DA 5I3MA 1KAPP 3EHXA 4FVLA 4GF1A 4XM6A 1HTDA 3EDZA 1KUGA 3WV3A 2K9CA 1OMJA 1S4BP 1HOVA 4G9LA 1C3IA 3DWBA 4H76A 1UMSA 3VI1A 1CAQA 1QJJA 4JPAA 2Y6DA 1I73A 1H71P 3LMCA 3AIGA 2DW2A 2W15A 3TT4A 2ERQA 1Q3AA 3L0TA 1C8TA 2J83A 4I03A 3K7NA 1GE6A 1GE5A 1IACA 1JH1A 2AIGP 4JP4A 1J7NA 1XFWA 2J0TA 1QICA 1MMQA 4GUYA 3CKIA 4JQGA 3P1VA 3TSKA 1SLNA 2HU6A 3LKAA 456CA 4DV8A 3K7LA 2MZEA 3AYKA 3KWVC 2YIGA 1PWWA 3UVCA 1XFZA 2YB9A 1MMRA 1GXDA 1OS9A 4DF9A 1O0QA 3LIRA 2E2DA 1KBCA 2X3CA 4XM8A 1JK3A 2L0RA 1GO8P 5B5OA 1XFYA 3RTSA 2OVZA 3LUMA 1USNA 3F18A 1OM8A 2USNA 3HY9A 4WF6A 4ZR5A 1OM7A 4XM7A 2ERPA 1RM8A 966CA 4GR3A 4IUWA 3DL1A 1DMTA 1B3DA 3DPFA 2Y6CA 1PWQA 3G42A 4DPEA 1KUHA 2POJA 1GO7P 3KEKA 2QPJA 1G9KA 4R3VA 4ON1A 1R1IA 5L7FA 1BQQM 3G5CA 2V4BA 1R1HA 4JIJA 4L63A 2XS4A 1K7GA 2W0DA 1RMZA 3KEJA 1OO9A 5I43A 4PKVA 1ATLA 2W14A 4H82A 4A3WA 3F17A 1CK7A 2X3AA 3LE9A 3U1RA 1I1IP 3HB2P 1BZSA 1YP1A 2MZHA 2OW9A 4L19A 3LILA 1JIZA 3I7IA 2AYKA 1XUCA 1YQYA 1A86A 1ZVXA 3ZVSA 5I0LA 1CQRA 3DSLA 1XURA 1BKCI 1CGLA 4PKTA 4H30A 1QJIA 4FXQA 1SATA 5B5PA 2K2GA 1HV5A 1IAGA 4I35A 2A8HA 1XFXA 3V96B 1MMPA 1Y8JA 2E3XA 3WV2A 1QIBA 3E8RA 5D1TA 1MNCA 1ZP5A 5D1UA 3P24A 2DW0A 3KMEA 4XCTA 3DPEA 4PKWA 2MZIA 4FU4A 1IABA 2OVXA 3ZXHA 5I2ZA 2CLTA 4PKRA 4DD8A 1ZXVA 3Q2HA 3N2VA 3HY7A 1EAKA 4WK7A 1UTTA 4WZVA 4AXQA 4H84A 3EDIA 4G0DA 1A85A 2JT5A 5D3CA 1AKLA 1PWUA 1Y0VA 2OW2A 3TVCA 2EROA 5I4OA 1SMPA 1EB6A 1YCMA 3LIKA 1IADA 2TCLA 1ROSA 4GWNA 1R54A 1AF0A 2FV9A 2N8RA 4L6TA 1FBLA 1PWVA 3HDBA 5L79A 2JT6A 3F19A 3KECA 2DDFA 4GR0A 3EWJA 2SRTA 3Q2GA 3KMCA 3LQ0A 1JKYA 3VTGA 1OS2A 1D7XA 3B92A 2FV5A 3LJGA 1K7IA 3HBVP 3MA2A 3LQBA 4AYKA 4GQLA 3O2XA 2I47A 3ZUKA 1CXVA 4CTHA 3EDHA 1ZS0A 1KUIA 2OW0A 1G4KA 2JSDA 2WO9A 1D8FA 2MLSA 4IN9A
chains in the Genus database with same CATH superfamily
1GKCA 1YOUA 1UEAA 4H1QA 4H2EA 2X7MA 1BUDA 1ZTQA 1BUVM 4QKZA 2OW1A 2DW1A 2XS3A 1HY7A 1Y93A 1BSWA 1CGFA 1GKDA 1B8YA 3USNA 4J4MA 1R1JA 2W13A 5BOYA 1WNIA 3SHIA 3F1AA 3AYUA 4AUOA 4FXYP 1MMBA 1DTHA 1BM6A 1KUKA 1PWPA 1ND1A 3O64A 3GBOA 4WKEA 1QUAA 3I7GA 3ELMA 4HMAA 1BKCA 2OXWA 2X3BA 1JAPA 1JIWP 1UMTA 5D1SA 1FLSA 1HFCA 3WV1A 2W12A 1BQOA 4XBHA 2MLRA 1L6JA 4GR8A 1XFUA 3F15A 4AIGA 2OZRA 1ZXCA 3LJTA 2JIHA 1G49A 4WKIA 3BA0A 3OHLA 3DNGA 3HDAP 1D5JA 1Z3JA 2D1OA 1SRPA 3RTTA 4A7BA 1QIAA 3KHIA 4H49A 2O36A 1XUDA 4IJOA 5BOTA 3LK8A 4HX3A 2RJQA 4JA1A 4ILWD 3F16A 2DDYA 4PKQA 2D1NA 1EUBA 1JANA 1CGEA 1ASTA 1G12A 4PKSA 1JJ9A 1KUFA 3L0VA 5D2BA 1SLMA 1OM6A 4L7AA 2OXZA 1UTZA 3EHYA 2RJPA 5JMYA 1XFVA 5CXAA 830CA 5LABA 3KRYA 3LGPA 5D7WA 3EDGA 3LEAA 1G05A 1K7QA 2WO8A 3TS4A 2JNPA 1BKCE 1IAAA 3LUNA 3B8ZA 1D8MA 4H3XA 1O0TA 4GWMA 5I12A 1FM1A 2O3EA 5H8XA 1GE7A 3OHOA 1SU3A 2WOAA 2OY4A 3LJZA 5BPAA 2OI0A 1R55A 2CKIA 2PJTA 5CZMA 1BIWA 1AYKA 1JAOA 1CIZA 1XAXA 5CUHA 3HYGA 1TVIA 2OY2A 1I76A 3N2UA 4EFSA 1IAEA 2OXUA 3NX7A 4Q1LA 3HBUP 1C7KA 1HFSA 1JAQA 4PKUA 2KRJA 3B2ZA 2Z2DA 5I3MA 1KAPP 3EHXA 4FVLA 4GF1A 4XM6A 1HTDA 3EDZA 1KUGA 3WV3A 2K9CA 1OMJA 1S4BP 1HOVA 4G9LA 1C3IA 3DWBA 4H76A 1UMSA 3VI1A 1CAQA 1QJJA 4JPAA 2Y6DA 1I73A 1H71P 3LMCA 3AIGA 2DW2A 2W15A 3TT4A 2ERQA 1Q3AA 3L0TA 1C8TA 2J83A 4I03A 3K7NA 1GE6A 1GE5A 1IACA 1JH1A 2AIGP 4JP4A 1J7NA 1XFWA 2J0TA 3DTEA 3DTIA 1QICA 1MMQA 4GUYA 3CKIA 4JQGA 3P1VA 3TSKA 1SLNA 2HU6A 3LKAA 456CA 4DV8A 3K7LA 2MZEA 3AYKA 3KWVC 2YIGA 1PWWA 3UVCA 1XFZA 2YB9A 1MMRA 1GXDA 1OS9A 4DF9A 1O0QA 3LIRA 2E2DA 1KBCA 2X3CA 4XM8A 1JK3A 2L0RA 1GO8P 5B5OA 1XFYA 3RTSA 2OVZA 3LUMA 1USNA 3F18A 1OM8A 2USNA 3HY9A 4WF6A 4ZR5A 1OM7A 4XM7A 2ERPA 1RM8A 966CA 4GR3A 4IUWA 3DL1A 1DMTA 1B3DA 3DPFA 2Y6CA 1PWQA 3G42A 4DPEA 1KUHA 2POJA 1GO7P 3KEKA 2QPJA 1G9KA 4R3VA 4ON1A 1R1IA 5L7FA 1BQQM 3G5CA 2V4BA 1R1HA 4JIJA 4L63A 2XS4A 1K7GA 2W0DA 1RMZA 3KEJA 1OO9A 5I43A 4PKVA 1ATLA 2W14A 4H82A 4A3WA 3F17A 1CK7A 2X3AA 3LE9A 3U1RA 1I1IP 3HB2P 1BZSA 1YP1A 2MZHA 2OW9A 4L19A 3LILA 1JIZA 3I7IA 2AYKA 1XUCA 1YQYA 1A86A 1ZVXA 3ZVSA 5I0LA 1CQRA 3DSLA 1XURA 1BKCI 1CGLA 4PKTA 4H30A 1QJIA 4FXQA 1SATA 5B5PA 2K2GA 1HV5A 1IAGA 4I35A 2A8HA 1XFXA 3V96B 1MMPA 1Y8JA 2E3XA 3WV2A 1QIBA 3E8RA 5D1TA 1MNCA 1ZP5A 5D1UA 3P24A 2DW0A 3KMEA 4XCTA 3DPEA 4PKWA 2MZIA 4FU4A 1IABA 2OVXA 3ZXHA 5I2ZA 2CLTA 4PKRA 4DD8A 1ZXVA 3Q2HA 3N2VA 3HY7A 1EAKA 4WK7A 1UTTA 4WZVA 1OZ9A 4AXQA 4H84A 3EDIA 4G0DA 1A85A 2JT5A 5D3CA 1AKLA 1PWUA 1Y0VA 2OW2A 3TVCA 2EROA 5I4OA 1SMPA 1EB6A 1YCMA 3LIKA 1IADA 2TCLA 1ROSA 4GWNA 1R54A 1AF0A 2FV9A 2N8RA 4L6TA 1FBLA 1PWVA 3DTKA 3HDBA 5L79A 2JT6A 3F19A 3KECA 2DDFA 4GR0A 3EWJA 2SRTA 3Q2GA 3KMCA 1XM5A 3LQ0A 1JKYA 3VTGA 1OS2A 1D7XA 3B92A 2FV5A 3LJGA 1K7IA 3HBVP 3MA2A 3LQBA 4AYKA 4GQLA 2YUFA 2I47A 3O2XA 3ZUKA 1CXVA 4CTHA 3EDHA 1ZS0A 1KUIA 2OW0A 1G4KA 2JSDA 2WO9A 1D8FA 2MLSA 4IN9A
chains in the Genus database with same CATH topology
1GKCA 1YOUA 1UEAA 4H1QA 4H2EA 2X7MA 1BUDA 1ZTQA 1BUVM 4QKZA 2OW1A 2DW1A 2XS3A 1HY7A 1Y93A 1BSWA 1CGFA 1GKDA 1B8YA 3USNA 4J4MA 1R1JA 2W13A 5BOYA 1WNIA 3SHIA 3F1AA 3AYUA 4AUOA 4FXYP 1MMBA 1DTHA 1BM6A 1KUKA 1PWPA 1ND1A 3O64A 3GBOA 4WKEA 1QUAA 3I7GA 3ELMA 4HMAA 1BKCA 2OXWA 2X3BA 1JAPA 1JIWP 1UMTA 5D1SA 1FLSA 1HFCA 3WV1A 2W12A 1BQOA 4XBHA 2MLRA 1L6JA 4GR8A 1XFUA 3F15A 4AIGA 2OZRA 1ZXCA 3LJTA 2JIHA 1G49A 4WKIA 3BA0A 3OHLA 3DNGA 3HDAP 1D5JA 1Z3JA 2D1OA 1SRPA 3RTTA 4A7BA 1QIAA 3KHIA 4H49A 2O36A 1XUDA 4IJOA 5BOTA 3LK8A 4HX3A 2RJQA 4JA1A 4ILWD 3F16A 2DDYA 4PKQA 2D1NA 1EUBA 1JANA 1CGEA 1ASTA 1G12A 4PKSA 1JJ9A 1KUFA 3L0VA 5D2BA 1SLMA 1OM6A 4L7AA 2OXZA 1UTZA 3EHYA 2RJPA 5JMYA 1XFVA 5CXAA 830CA 5LABA 3KRYA 3LGPA 5D7WA 3EDGA 3LEAA 1G05A 1K7QA 2WO8A 3TS4A 2JNPA 1BKCE 1IAAA 3LUNA 3B8ZA 1D8MA 4H3XA 1O0TA 4GWMA 5I12A 1FM1A 2O3EA 5H8XA 1GE7A 3OHOA 1SU3A 2WOAA 2OY4A 3LJZA 5BPAA 2OI0A 1R55A 2CKIA 2PJTA 5CZMA 1BIWA 1AYKA 1JAOA 1CIZA 5CUHA 3HYGA 2OY2A 1I76A 3N2UA 4EFSA 1IAEA 2OXUA 3NX7A 4Q1LA 3HBUP 1C7KA 1HFSA 1JAQA 4PKUA 2KRJA 3B2ZA 2Z2DA 5I3MA 1KAPP 3EHXA 4FVLA 4GF1A 4XM6A 1HTDA 3EDZA 1KUGA 3WV3A 2K9CA 1OMJA 1S4BP 1HOVA 4G9LA 1C3IA 3DWBA 4H76A 1UMSA 3VI1A 1CAQA 1QJJA 4JPAA 2Y6DA 1I73A 1H71P 3LMCA 3AIGA 2DW2A 2W15A 3TT4A 2ERQA 1Q3AA 3L0TA 1C8TA 2J83A 4I03A 3K7NA 1GE6A 1GE5A 1IACA 1JH1A 2AIGP 4JP4A 1J7NA 1XFWA 2J0TA 3DTEA 3DTIA 1QICA 1MMQA 4GUYA 3CKIA 4JQGA 3P1VA 3TSKA 1SLNA 2HU6A 3LKAA 456CA 4DV8A 3K7LA 2MZEA 3AYKA 3KWVC 2YIGA 1PWWA 3UVCA 1XFZA 2YB9A 1MMRA 1GXDA 1OS9A 4DF9A 1O0QA 3LIRA 2E2DA 1KBCA 2X3CA 4XM8A 1JK3A 2L0RA 1GO8P 5B5OA 1XFYA 3RTSA 2OVZA 3LUMA 1USNA 3F18A 1OM8A 2USNA 3HY9A 4WF6A 4ZR5A 1OM7A 4XM7A 2ERPA 1RM8A 966CA 4GR3A 4IUWA 3DL1A 1DMTA 1B3DA 3DPFA 2Y6CA 1PWQA 3G42A 4DPEA 1KUHA 2POJA 1GO7P 3KEKA 2QPJA 1G9KA 4R3VA 4ON1A 1R1IA 5L7FA 1BQQM 3G5CA 2V4BA 1R1HA 4JIJA 4L63A 2XS4A 1K7GA 2W0DA 1RMZA 3KEJA 1OO9A 5I43A 4PKVA 1ATLA 2W14A 4H82A 4A3WA 3F17A 1CK7A 2X3AA 3LE9A 3U1RA 1I1IP 3HB2P 1BZSA 1YP1A 2MZHA 2OW9A 4L19A 3LILA 1JIZA 3I7IA 2AYKA 1XUCA 1YQYA 1A86A 1ZVXA 3ZVSA 5I0LA 1CQRA 3DSLA 1XURA 1BKCI 1CGLA 4PKTA 4H30A 1QJIA 4FXQA 1SATA 5B5PA 2K2GA 1HV5A 1IAGA 4I35A 2A8HA 1XFXA 3V96B 1MMPA 1Y8JA 2E3XA 3WV2A 1QIBA 3E8RA 5D1TA 1MNCA 1ZP5A 5D1UA 3P24A 2DW0A 3KMEA 4XCTA 3DPEA 4PKWA 2MZIA 4FU4A 1IABA 2OVXA 3ZXHA 5I2ZA 2CLTA 4PKRA 4DD8A 1ZXVA 3Q2HA 3N2VA 3HY7A 1EAKA 4WK7A 1UTTA 4WZVA 4AXQA 4H84A 3EDIA 4G0DA 1A85A 2JT5A 5D3CA 1AKLA 1PWUA 1Y0VA 2OW2A 3TVCA 2EROA 5I4OA 1SMPA 1EB6A 1YCMA 3LIKA 1IADA 2TCLA 1ROSA 4GWNA 1R54A 1AF0A 2FV9A 2N8RA 4L6TA 1FBLA 1PWVA 3DTKA 3HDBA 5L79A 2JT6A 3F19A 3KECA 2DDFA 4GR0A 3EWJA 2SRTA 3Q2GA 3KMCA 3LQ0A 1JKYA 3VTGA 1OS2A 1D7XA 3B92A 2FV5A 3LJGA 1K7IA 3HBVP 3MA2A 3LQBA 4AYKA 4GQLA 2YUFA 2I47A 3O2XA 3ZUKA 1CXVA 4CTHA 3EDHA 1ZS0A 1KUIA 2OW0A 1G4KA 2JSDA 2WO9A 1D8FA 2MLSA 4IN9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKC A;  1YOU A;  1UEA A;  4H1Q A;  4H2E A;  2X7M A;  1BUD A;  1ZTQ A;  1BUV M;  4QKZ A;  2OW1 A;  2DW1 A;  2XS3 A;  1HY7 A;  1Y93 A;  1BSW A;  1CGF A;  1GKD A;  1B8Y A;  3USN A;  4J4M A;  1R1J A;  2W13 A;  5BOY A;  1WNI A;  3SHI A;  3F1A A;  3AYU A;  4AUO A;  4FXY P;  1MMB A;  1DTH A;  1BM6 A;  1KUK A;  1PWP A;  1ND1 A;  3O64 A;  3GBO A;  4WKE A;  1QUA A;  3I7G A;  3ELM A;  4HMA A;  1BKC A;  2OXW A;  2X3B A;  1JAP A;  1JIW P;  1UMT A;  5D1S A;  1FLS A;  1HFC A;  3WV1 A;  2W12 A;  1BQO A;  4XBH A;  2MLR A;  1L6J A;  4GR8 A;  1XFU A;  3F15 A;  4AIG A;  2OZR A;  1ZXC A;  3LJT A;  2JIH A;  1G49 A;  4WKI A;  3BA0 A;  3OHL A;  3DNG A;  3HDA P;  1D5J A;  1Z3J A;  2D1O A;  1SRP A;  3RTT A;  4A7B A;  1QIA A;  3KHI A;  4H49 A;  2O36 A;  1XUD A;  4IJO A;  5BOT A;  3LK8 A;  4HX3 A;  2RJQ A;  4JA1 A;  4ILW D;  3F16 A;  2DDY A;  4PKQ A;  2D1N A;  1EUB A;  1JAN A;  1CGE A;  1AST A;  1G12 A;  4PKS A;  1JJ9 A;  1KUF A;  3L0V A;  5D2B A;  1SLM A;  1OM6 A;  2OXZ A;  1UTZ A;  3EHY A;  2RJP A;  5JMY A;  1XFV A;  5CXA A;  830C A;  5LAB A;  3KRY A;  3LGP A;  5D7W A;  3EDG A;  3LEA A;  1G05 A;  1K7Q A;  2WO8 A;  3TS4 A;  2JNP A;  1BKC E;  1IAA A;  3LUN A;  3B8Z A;  1D8M A;  4H3X A;  1O0T A;  4GWM A;  5I12 A;  1FM1 A;  2O3E A;  5H8X A;  1GE7 A;  3OHO A;  1SU3 A;  2WOA A;  2OY4 A;  3LJZ A;  5BPA A;  2OI0 A;  1R55 A;  2CKI A;  2PJT A;  5CZM A;  1BIW A;  1AYK A;  1JAO A;  1CIZ A;  5CUH A;  3HYG A;  2OY2 A;  1I76 A;  3N2U A;  4EFS A;  1IAE A;  2OXU A;  3NX7 A;  4Q1L A;  3HBU P;  1C7K A;  1HFS A;  1JAQ A;  4PKU A;  2KRJ A;  3B2Z A;  2Z2D A;  5I3M A;  1KAP P;  3EHX A;  4FVL A;  4GF1 A;  4XM6 A;  1HTD A;  3EDZ A;  1KUG A;  3WV3 A;  2K9C A;  1OMJ A;  1S4B P;  1HOV A;  4G9L A;  1C3I A;  3DWB A;  4H76 A;  1UMS A;  3VI1 A;  1CAQ A;  1QJJ A;  4JPA A;  2Y6D A;  1I73 A;  1H71 P;  3LMC A;  3AIG A;  2DW2 A;  2W15 A;  3TT4 A;  2ERQ A;  1Q3A A;  3L0T A;  1C8T A;  2J83 A;  4I03 A;  3K7N A;  1GE6 A;  1GE5 A;  1IAC A;  1JH1 A;  2AIG P;  4JP4 A;  1J7N A;  1XFW A;  2J0T A;  1QIC A;  1MMQ A;  4GUY A;  3CKI A;  4JQG A;  3P1V A;  3TSK A;  1SLN A;  2HU6 A;  3LKA A;  456C A;  4DV8 A;  3K7L A;  2MZE A;  3AYK A;  3KWV C;  2YIG A;  1PWW A;  3UVC A;  1XFZ A;  2YB9 A;  1MMR A;  1GXD A;  1OS9 A;  4DF9 A;  1O0Q A;  3LIR A;  2E2D A;  1KBC A;  2X3C A;  4XM8 A;  1JK3 A;  2L0R A;  1GO8 P;  5B5O A;  1XFY A;  3RTS A;  2OVZ A;  3LUM A;  1USN A;  3F18 A;  1OM8 A;  2USN A;  3HY9 A;  4WF6 A;  4ZR5 A;  1OM7 A;  4XM7 A;  2ERP A;  1RM8 A;  966C A;  4GR3 A;  4IUW A;  3DL1 A;  1DMT A;  1B3D A;  3DPF A;  2Y6C A;  1PWQ A;  3G42 A;  4DPE A;  1KUH A;  2POJ A;  1GO7 P;  3KEK A;  2QPJ A;  1G9K A;  4R3V A;  4ON1 A;  1R1I A;  5L7F A;  1BQQ M;  3G5C A;  2V4B A;  1R1H A;  4JIJ A;  4L63 A;  2XS4 A;  1K7G A;  2W0D A;  1RMZ A;  3KEJ A;  1OO9 A;  5I43 A;  4PKV A;  1ATL A;  2W14 A;  4H82 A;  4A3W A;  3F17 A;  1CK7 A;  2X3A A;  3LE9 A;  3U1R A;  1I1I P;  3HB2 P;  1BZS A;  1YP1 A;  2MZH A;  2OW9 A;  4L19 A;  3LIL A;  1JIZ A;  3I7I A;  2AYK A;  1XUC A;  1YQY A;  1A86 A;  1ZVX A;  3ZVS A;  5I0L A;  1CQR A;  3DSL A;  1XUR A;  1BKC I;  1CGL A;  4PKT A;  4H30 A;  1QJI A;  4FXQ A;  1SAT A;  5B5P A;  2K2G A;  1HV5 A;  1IAG A;  4I35 A;  2A8H A;  1XFX A;  3V96 B;  1MMP A;  1Y8J A;  2E3X A;  3WV2 A;  1QIB A;  3E8R A;  5D1T A;  1MNC A;  1ZP5 A;  5D1U A;  3P24 A;  2DW0 A;  3KME A;  4XCT A;  3DPE A;  4PKW A;  2MZI A;  4FU4 A;  1IAB A;  2OVX A;  3ZXH A;  5I2Z A;  2CLT A;  4PKR A;  4DD8 A;  1ZXV A;  3Q2H A;  3N2V A;  3HY7 A;  1EAK A;  4WK7 A;  1UTT A;  4WZV A;  4AXQ A;  4H84 A;  3EDI A;  4G0D A;  1A85 A;  2JT5 A;  5D3C A;  1AKL A;  1PWU A;  1Y0V A;  2OW2 A;  3TVC A;  2ERO A;  5I4O A;  1SMP A;  1EB6 A;  1YCM A;  3LIK A;  1IAD A;  2TCL A;  1ROS A;  4GWN A;  1R54 A;  1AF0 A;  2FV9 A;  2N8R A;  4L6T A;  1FBL A;  1PWV A;  3HDB A;  5L79 A;  2JT6 A;  3F19 A;  3KEC A;  2DDF A;  4GR0 A;  3EWJ A;  2SRT A;  3Q2G A;  3KMC A;  3LQ0 A;  1JKY A;  3VTG A;  1OS2 A;  1D7X A;  3B92 A;  2FV5 A;  3LJG A;  1K7I A;  3HBV P;  3MA2 A;  3LQB A;  4AYK A;  4GQL A;  3O2X A;  2I47 A;  3ZUK A;  1CXV A;  4CTH A;  3EDH A;  1ZS0 A;  1KUI A;  2OW0 A;  1G4K A;  2JSD A;  2WO9 A;  1D8F A;  2MLS A;  4IN9 A; 
#chains in the Genus database with same CATH topology
 1GKC A;  1YOU A;  1UEA A;  4H1Q A;  4H2E A;  2X7M A;  1BUD A;  1ZTQ A;  1BUV M;  4QKZ A;  2OW1 A;  2DW1 A;  2XS3 A;  1HY7 A;  1Y93 A;  1BSW A;  1CGF A;  1GKD A;  1B8Y A;  3USN A;  4J4M A;  1R1J A;  2W13 A;  5BOY A;  1WNI A;  3SHI A;  3F1A A;  3AYU A;  4AUO A;  4FXY P;  1MMB A;  1DTH A;  1BM6 A;  1KUK A;  1PWP A;  1ND1 A;  3O64 A;  3GBO A;  4WKE A;  1QUA A;  3I7G A;  3ELM A;  4HMA A;  1BKC A;  2OXW A;  2X3B A;  1JAP A;  1JIW P;  1UMT A;  5D1S A;  1FLS A;  1HFC A;  3WV1 A;  2W12 A;  1BQO A;  4XBH A;  2MLR A;  1L6J A;  4GR8 A;  1XFU A;  3F15 A;  4AIG A;  2OZR A;  1ZXC A;  3LJT A;  2JIH A;  1G49 A;  4WKI A;  3BA0 A;  3OHL A;  3DNG A;  3HDA P;  1D5J A;  1Z3J A;  2D1O A;  1SRP A;  3RTT A;  4A7B A;  1QIA A;  3KHI A;  4H49 A;  2O36 A;  1XUD A;  4IJO A;  5BOT A;  3LK8 A;  4HX3 A;  2RJQ A;  4JA1 A;  4ILW D;  3F16 A;  2DDY A;  4PKQ A;  2D1N A;  1EUB A;  1JAN A;  1CGE A;  1AST A;  1G12 A;  4PKS A;  1JJ9 A;  1KUF A;  3L0V A;  5D2B A;  1SLM A;  1OM6 A;  4L7A A;  2OXZ A;  1UTZ A;  3EHY A;  2RJP A;  5JMY A;  1XFV A;  5CXA A;  830C A;  5LAB A;  3KRY A;  3LGP A;  5D7W A;  3EDG A;  3LEA A;  1G05 A;  1K7Q A;  2WO8 A;  3TS4 A;  2JNP A;  1BKC E;  1IAA A;  3LUN A;  3B8Z A;  1D8M A;  4H3X A;  1O0T A;  4GWM A;  5I12 A;  1FM1 A;  2O3E A;  5H8X A;  1GE7 A;  3OHO A;  1SU3 A;  2WOA A;  2OY4 A;  3LJZ A;  5BPA A;  2OI0 A;  1R55 A;  2CKI A;  2PJT A;  5CZM A;  1BIW A;  1AYK A;  1JAO A;  1CIZ A;  1XAX A;  5CUH A;  3HYG A;  1TVI A;  2OY2 A;  1I76 A;  3N2U A;  4EFS A;  1IAE A;  2OXU A;  3NX7 A;  4Q1L A;  3HBU P;  1C7K A;  1HFS A;  1JAQ A;  4PKU A;  2KRJ A;  3B2Z A;  2Z2D A;  5I3M A;  1KAP P;  3EHX A;  4FVL A;  4GF1 A;  4XM6 A;  1HTD A;  3EDZ A;  1KUG A;  3WV3 A;  2K9C A;  1OMJ A;  1S4B P;  1HOV A;  4G9L A;  1C3I A;  3DWB A;  4H76 A;  1UMS A;  3VI1 A;  1CAQ A;  1QJJ A;  4JPA A;  2Y6D A;  1I73 A;  1H71 P;  3LMC A;  3AIG A;  2DW2 A;  2W15 A;  3TT4 A;  2ERQ A;  1Q3A A;  3L0T A;  1C8T A;  2J83 A;  4I03 A;  3K7N A;  1GE6 A;  1GE5 A;  1IAC A;  1JH1 A;  2AIG P;  4JP4 A;  1J7N A;  1XFW A;  2J0T A;  3DTE A;  3DTI A;  1QIC A;  1MMQ A;  4GUY A;  3CKI A;  4JQG A;  3P1V A;  3TSK A;  1SLN A;  2HU6 A;  3LKA A;  456C A;  4DV8 A;  3K7L A;  2MZE A;  3AYK A;  3KWV C;  2YIG A;  1PWW A;  3UVC A;  1XFZ A;  2YB9 A;  1MMR A;  1GXD A;  1OS9 A;  4DF9 A;  1O0Q A;  3LIR A;  2E2D A;  1KBC A;  2X3C A;  4XM8 A;  1JK3 A;  2L0R A;  1GO8 P;  5B5O A;  1XFY A;  3RTS A;  2OVZ A;  3LUM A;  1USN A;  3F18 A;  1OM8 A;  2USN A;  3HY9 A;  4WF6 A;  4ZR5 A;  1OM7 A;  4XM7 A;  2ERP A;  1RM8 A;  966C A;  4GR3 A;  4IUW A;  3DL1 A;  1DMT A;  1B3D A;  3DPF A;  2Y6C A;  1PWQ A;  3G42 A;  4DPE A;  1KUH A;  2POJ A;  1GO7 P;  3KEK A;  2QPJ A;  1G9K A;  4R3V A;  4ON1 A;  1R1I A;  5L7F A;  1BQQ M;  3G5C A;  2V4B A;  1R1H A;  4JIJ A;  4L63 A;  2XS4 A;  1K7G A;  2W0D A;  1RMZ A;  3KEJ A;  1OO9 A;  5I43 A;  4PKV A;  1ATL A;  2W14 A;  4H82 A;  4A3W A;  3F17 A;  1CK7 A;  2X3A A;  3LE9 A;  3U1R A;  1I1I P;  3HB2 P;  1BZS A;  1YP1 A;  2MZH A;  2OW9 A;  4L19 A;  3LIL A;  1JIZ A;  3I7I A;  2AYK A;  1XUC A;  1YQY A;  1A86 A;  1ZVX A;  3ZVS A;  5I0L A;  1CQR A;  3DSL A;  1XUR A;  1BKC I;  1CGL A;  4PKT A;  4H30 A;  1QJI A;  4FXQ A;  1SAT A;  5B5P A;  2K2G A;  1HV5 A;  1IAG A;  4I35 A;  2A8H A;  1XFX A;  3V96 B;  1MMP A;  1Y8J A;  2E3X A;  3WV2 A;  1QIB A;  3E8R A;  5D1T A;  1MNC A;  1ZP5 A;  5D1U A;  3P24 A;  2DW0 A;  3KME A;  4XCT A;  3DPE A;  4PKW A;  2MZI A;  4FU4 A;  1IAB A;  2OVX A;  3ZXH A;  5I2Z A;  2CLT A;  4PKR A;  4DD8 A;  1ZXV A;  3Q2H A;  3N2V A;  3HY7 A;  1EAK A;  4WK7 A;  1UTT A;  4WZV A;  1OZ9 A;  4AXQ A;  4H84 A;  3EDI A;  4G0D A;  1A85 A;  2JT5 A;  5D3C A;  1AKL A;  1PWU A;  1Y0V A;  2OW2 A;  3TVC A;  2ERO A;  5I4O A;  1SMP A;  1EB6 A;  1YCM A;  3LIK A;  1IAD A;  2TCL A;  1ROS A;  4GWN A;  1R54 A;  1AF0 A;  2FV9 A;  2N8R A;  4L6T A;  1FBL A;  1PWV A;  3DTK A;  3HDB A;  5L79 A;  2JT6 A;  3F19 A;  3KEC A;  2DDF A;  4GR0 A;  3EWJ A;  2SRT A;  3Q2G A;  3KMC A;  1XM5 A;  3LQ0 A;  1JKY A;  3VTG A;  1OS2 A;  1D7X A;  3B92 A;  2FV5 A;  3LJG A;  1K7I A;  3HBV P;  3MA2 A;  3LQB A;  4AYK A;  4GQL A;  2YUF A;  2I47 A;  3O2X A;  3ZUK A;  1CXV A;  4CTH A;  3EDH A;  1ZS0 A;  1KUI A;  2OW0 A;  1G4K A;  2JSD A;  2WO9 A;  1D8F A;  2MLS A;  4IN9 A; 
#chains in the Genus database with same CATH homology
 1GKC A;  1YOU A;  1UEA A;  4H1Q A;  4H2E A;  2X7M A;  1BUD A;  1ZTQ A;  1BUV M;  4QKZ A;  2OW1 A;  2DW1 A;  2XS3 A;  1HY7 A;  1Y93 A;  1BSW A;  1CGF A;  1GKD A;  1B8Y A;  3USN A;  4J4M A;  1R1J A;  2W13 A;  5BOY A;  1WNI A;  3SHI A;  3F1A A;  3AYU A;  4AUO A;  4FXY P;  1MMB A;  1DTH A;  1BM6 A;  1KUK A;  1PWP A;  1ND1 A;  3O64 A;  3GBO A;  4WKE A;  1QUA A;  3I7G A;  3ELM A;  4HMA A;  1BKC A;  2OXW A;  2X3B A;  1JAP A;  1JIW P;  1UMT A;  5D1S A;  1FLS A;  1HFC A;  3WV1 A;  2W12 A;  1BQO A;  4XBH A;  2MLR A;  1L6J A;  4GR8 A;  1XFU A;  3F15 A;  4AIG A;  2OZR A;  1ZXC A;  3LJT A;  2JIH A;  1G49 A;  4WKI A;  3BA0 A;  3OHL A;  3DNG A;  3HDA P;  1D5J A;  1Z3J A;  2D1O A;  1SRP A;  3RTT A;  4A7B A;  1QIA A;  3KHI A;  4H49 A;  2O36 A;  1XUD A;  4IJO A;  5BOT A;  3LK8 A;  4HX3 A;  2RJQ A;  4JA1 A;  4ILW D;  3F16 A;  2DDY A;  4PKQ A;  2D1N A;  1EUB A;  1JAN A;  1CGE A;  1AST A;  1G12 A;  4PKS A;  1JJ9 A;  1KUF A;  3L0V A;  5D2B A;  1SLM A;  1OM6 A;  4L7A A;  2OXZ A;  1UTZ A;  3EHY A;  2RJP A;  5JMY A;  1XFV A;  5CXA A;  830C A;  5LAB A;  3KRY A;  3LGP A;  5D7W A;  3EDG A;  3LEA A;  1G05 A;  1K7Q A;  2WO8 A;  3TS4 A;  2JNP A;  1BKC E;  1IAA A;  3LUN A;  3B8Z A;  1D8M A;  4H3X A;  1O0T A;  4GWM A;  5I12 A;  1FM1 A;  2O3E A;  5H8X A;  1GE7 A;  3OHO A;  1SU3 A;  2WOA A;  2OY4 A;  3LJZ A;  5BPA A;  2OI0 A;  1R55 A;  2CKI A;  2PJT A;  5CZM A;  1BIW A;  1AYK A;  1JAO A;  1CIZ A;  5CUH A;  3HYG A;  2OY2 A;  1I76 A;  3N2U A;  4EFS A;  1IAE A;  2OXU A;  3NX7 A;  4Q1L A;  3HBU P;  1C7K A;  1HFS A;  1JAQ A;  4PKU A;  2KRJ A;  3B2Z A;  2Z2D A;  5I3M A;  1KAP P;  3EHX A;  4FVL A;  4GF1 A;  4XM6 A;  1HTD A;  3EDZ A;  1KUG A;  3WV3 A;  2K9C A;  1OMJ A;  1S4B P;  1HOV A;  4G9L A;  1C3I A;  3DWB A;  4H76 A;  1UMS A;  3VI1 A;  1CAQ A;  1QJJ A;  4JPA A;  2Y6D A;  1I73 A;  1H71 P;  3LMC A;  3AIG A;  2DW2 A;  2W15 A;  3TT4 A;  2ERQ A;  1Q3A A;  3L0T A;  1C8T A;  2J83 A;  4I03 A;  3K7N A;  1GE6 A;  1GE5 A;  1IAC A;  1JH1 A;  2AIG P;  4JP4 A;  1J7N A;  1XFW A;  2J0T A;  3DTE A;  3DTI A;  1QIC A;  1MMQ A;  4GUY A;  3CKI A;  4JQG A;  3P1V A;  3TSK A;  1SLN A;  2HU6 A;  3LKA A;  456C A;  4DV8 A;  3K7L A;  2MZE A;  3AYK A;  3KWV C;  2YIG A;  1PWW A;  3UVC A;  1XFZ A;  2YB9 A;  1MMR A;  1GXD A;  1OS9 A;  4DF9 A;  1O0Q A;  3LIR A;  2E2D A;  1KBC A;  2X3C A;  4XM8 A;  1JK3 A;  2L0R A;  1GO8 P;  5B5O A;  1XFY A;  3RTS A;  2OVZ A;  3LUM A;  1USN A;  3F18 A;  1OM8 A;  2USN A;  3HY9 A;  4WF6 A;  4ZR5 A;  1OM7 A;  4XM7 A;  2ERP A;  1RM8 A;  966C A;  4GR3 A;  4IUW A;  3DL1 A;  1DMT A;  1B3D A;  3DPF A;  2Y6C A;  1PWQ A;  3G42 A;  4DPE A;  1KUH A;  2POJ A;  1GO7 P;  3KEK A;  2QPJ A;  1G9K A;  4R3V A;  4ON1 A;  1R1I A;  5L7F A;  1BQQ M;  3G5C A;  2V4B A;  1R1H A;  4JIJ A;  4L63 A;  2XS4 A;  1K7G A;  2W0D A;  1RMZ A;  3KEJ A;  1OO9 A;  5I43 A;  4PKV A;  1ATL A;  2W14 A;  4H82 A;  4A3W A;  3F17 A;  1CK7 A;  2X3A A;  3LE9 A;  3U1R A;  1I1I P;  3HB2 P;  1BZS A;  1YP1 A;  2MZH A;  2OW9 A;  4L19 A;  3LIL A;  1JIZ A;  3I7I A;  2AYK A;  1XUC A;  1YQY A;  1A86 A;  1ZVX A;  3ZVS A;  5I0L A;  1CQR A;  3DSL A;  1XUR A;  1BKC I;  1CGL A;  4PKT A;  4H30 A;  1QJI A;  4FXQ A;  1SAT A;  5B5P A;  2K2G A;  1HV5 A;  1IAG A;  4I35 A;  2A8H A;  1XFX A;  3V96 B;  1MMP A;  1Y8J A;  2E3X A;  3WV2 A;  1QIB A;  3E8R A;  5D1T A;  1MNC A;  1ZP5 A;  5D1U A;  3P24 A;  2DW0 A;  3KME A;  4XCT A;  3DPE A;  4PKW A;  2MZI A;  4FU4 A;  1IAB A;  2OVX A;  3ZXH A;  5I2Z A;  2CLT A;  4PKR A;  4DD8 A;  1ZXV A;  3Q2H A;  3N2V A;  3HY7 A;  1EAK A;  4WK7 A;  1UTT A;  4WZV A;  4AXQ A;  4H84 A;  3EDI A;  4G0D A;  1A85 A;  2JT5 A;  5D3C A;  1AKL A;  1PWU A;  1Y0V A;  2OW2 A;  3TVC A;  2ERO A;  5I4O A;  1SMP A;  1EB6 A;  1YCM A;  3LIK A;  1IAD A;  2TCL A;  1ROS A;  4GWN A;  1R54 A;  1AF0 A;  2FV9 A;  2N8R A;  4L6T A;  1FBL A;  1PWV A;  3DTK A;  3HDB A;  5L79 A;  2JT6 A;  3F19 A;  3KEC A;  2DDF A;  4GR0 A;  3EWJ A;  2SRT A;  3Q2G A;  3KMC A;  3LQ0 A;  1JKY A;  3VTG A;  1OS2 A;  1D7X A;  3B92 A;  2FV5 A;  3LJG A;  1K7I A;  3HBV P;  3MA2 A;  3LQB A;  4AYK A;  4GQL A;  2YUF A;  2I47 A;  3O2X A;  3ZUK A;  1CXV A;  4CTH A;  3EDH A;  1ZS0 A;  1KUI A;  2OW0 A;  1G4K A;  2JSD A;  2WO9 A;  1D8F A;  2MLS A;  4IN9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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