3L0VA

Crystal structure of catalytic domain of tace with the first hydantoin inhibitor occupying the s1' pocket
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
255
Chain Sequence
ADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Discovery and SAR of hydantoin TACE inhibitors.
pubmed doi rcsb
molecule keywords Disintegrin and metalloproteinase domain-containing protein
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 83
structure length 255
sequence length 259
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2009-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3l0vA00
3F17A 4GUYA 1JK3A 1JIWP 1BKCE 2YB9A 5BOTA 2D1NA 5H8XA 2OVXA 5D3CA 2D1OA 3LUNA 1ND1A 2OW2A 4GR8A 2EROA 3KEKA 1JAPA 2K2GA 1JANA 1BZSA 4JQGA 3G42A 2E2DA 2MZHA 4AYKA 3EDZA 3EHYA 3HY7A 2I47A 2PJTA 1EB6A 1IACA 4G9LA 4JP4A 2OW9A 3TSKA 1DTHA 4H2EA 1G49A 1BUDA 1IAAA 2WO9A 4WKEA 4PKVA 3F19A 1I73A 2V4BA 2ERQA 4HMAA 3HDAP 5CXAA 3DPFA 3N2UA 3EDGA 4WZVA 1PWVA 3I7GA 1CGFA 1C8TA 1XUCA 3LILA 3K7LA 3LK8A 5LABA 3KECA 1KAPP 456CA 1CXVA 4ILWD 3LQ0A 2X3CA 3B2ZA 1GO7P 1YQYA 1IABA 3HBVP 1XFUA 3LUMA 1Y93A 1RMZA 3WV3A 1HFCA 3O2XA 1XFYA 3O64A 3VTGA 1R55A 1G05A 1OO9A 4G0DA 1UMSA 1ZTQA 2MLRA 2RJPA 1MMQA 5D1SA 5B5PA 830CA 1CK7A 1MMBA 2WO8A 1FBLA 3K7NA 2J0TA 3EDIA 4DPEA 1ROSA 2W12A 1FM1A 4AXQA 1DMTA 3HY9A 2W14A 5D1UA 1L6JA 1IADA 1ZP5A 2SRTA 4L19A 1B8YA 2OXWA 1SLNA 4H82A 2J83A 3Q2HA 1QJIA 5I12A 3B92A 4H49A 1ZXCA 3ZVSA 1UTTA 2DW0A 4PKSA 1GKCA 2YIGA 3LJZA 1KUFA 2OXUA 1R1IA 1H71P 4XCTA 1HFSA 1QUAA 3AIGA 2O3EA 1K7IA 1QIBA 2JT6A 1KUKA 1G12A 3LKAA 1ZVXA 2AYKA 3Q2GA 2DW1A 4GWMA 1GO8P 4IJOA 4IUWA 1CGEA 1G9KA 2X3BA 3L0VA 3ZUKA 1XFVA 4GWNA 1JIZA 4AUOA 2ERPA 4XM6A 1CIZA 1GE7A 1BUVM 1QIAA 3ELMA 2WOAA 1OM8A 1A85A 3P24A 1XFXA 1AF0A 1ZS0A 3LIKA 1OM7A 2N8RA 1R54A 1XFWA 3LIRA 1I76A 2XS4A 5D1TA 2JNPA 4L6TA 1HTDA 4CTHA 4JA1A 4H1QA 1BQOA 4EFSA 4WKIA 966CA 1GXDA 4FXQA 3HDBA 1FLSA 3I7IA 2X7MA 1ASTA 4PKQA 2MLSA 1O0QA 1Q3AA 3AYKA 4JIJA 2JIHA 1Y0VA 5I0LA 1A86A 1CGLA 3LJTA 4A7BA 1SMPA 3LQBA 4PKWA 3RTSA 2RJQA 3KMCA 4XM7A 2USNA 4A3WA 1OMJA 1PWUA 3MA2A 1XURA 4DD8A 1USNA 5D7WA 3KEJA 3DPEA 1CQRA 4JPAA 2OY2A 1PWWA 1MMPA 3RTTA 1PWQA 2CLTA 3HYGA 1HV5A 3P1VA 3EWJA 4PKRA 3TVCA 1K7GA 1OS9A 1JAOA 2O36A 2E3XA 3F15A 3LE9A 3V96B 1OM6A 3EDHA 3DNGA 5JMYA 5CUHA 3GBOA 4R3VA 1RM8A 3L0TA 1I1IP 3HBUP 2OVZA 1HOVA 4H3XA 1IAEA 3N2VA 1D7XA 1YOUA 3DSLA 4GR0A 3TT4A 2OZRA 2AIGP 5L79A 3AYUA 4WF6A 1GE6A 1R1HA 3TS4A 1Y8JA 3DL1A 5L7FA 4XBHA 2OW1A 3F18A 1JKYA 2L0RA 2KRJA 2Y6DA 3OHLA 2FV5A 2FV9A 4AIGA 1QICA 5I3MA 1BQQM 1MNCA 3BA0A 4ON1A 1HY7A 3NX7A 3EHXA 1D8MA 1YP1A 5B5OA 2Y6CA 1G4KA 3KWVC 1SATA 4HX3A 1SLMA 1AKLA 1BSWA 1GKDA 4QKZA 3KRYA 4FU4A 4L63A 1ATLA 5D2BA 1UEAA 2OI0A 3F16A 1SRPA 4H76A 1JAQA 2POJA 1YCMA 5I43A 5BOYA 1IAGA 1EUBA 4FVLA 3SHIA 1UTZA 3E8RA 3KHIA 3KMEA 5I4OA 4PKTA 3G5CA 4J4MA 3B8ZA 4GF1A 3VI1A 4FXYP 1KBCA 1BKCI 4GQLA 1ZXVA 2HU6A 1O0TA 1J7NA 2OY4A 1EAKA 3HB2P 4PKUA 2W0DA 3LGPA 4Q1LA 4I03A 3UVCA 2CKIA 4XM8A 2W15A 2QPJA 3WV1A 3OHOA 4H30A 1S4BP 1OS2A 1JH1A 2MZEA 3ZXHA 1KUHA 2JSDA 2TCLA 3WV2A 1D5JA 4DV8A 1PWPA 2A8HA 2JT5A 1JJ9A 2K9CA 4IN9A 1KUGA 1BKCA 1K7QA 2W13A 1WNIA 2OXZA 1R1JA 4WK7A 2DW2A 1CAQA 1QJJA 5BPAA 4H84A 2XS3A 4GR3A 1C3IA 1BIWA 3LJGA 1UMTA 5I2ZA 3U1RA 3CKIA 1GE5A 1XUDA 3DWBA 2OW0A 3LMCA 4ZR5A 3LEAA 1SU3A 3USNA 2X3AA 2Z2DA 4DF9A 1C7KA 2MZIA 1MMRA 1KUIA 1Z3JA 1BM6A 3F1AA 1XFZA 1AYKA 4I35A 2DDYA 1B3DA 5CZMA 1D8FA 2DDFA
chains in the Genus database with same CATH superfamily
3F17A 4GUYA 1JK3A 1JIWP 1BKCE 2YB9A 5BOTA 2D1NA 2YUFA 5H8XA 2OVXA 5D3CA 2D1OA 3LUNA 1ND1A 2OW2A 4GR8A 2EROA 3KEKA 1JAPA 2K2GA 1JANA 1BZSA 4JQGA 3G42A 2E2DA 2MZHA 4AYKA 3EDZA 3EHYA 3HY7A 2I47A 2PJTA 1EB6A 1IACA 4G9LA 4JP4A 2OW9A 3TSKA 1DTHA 3DTIA 4H2EA 1G49A 1BUDA 1IAAA 2WO9A 4WKEA 4PKVA 3F19A 1I73A 2V4BA 2ERQA 4HMAA 3HDAP 5CXAA 3DPFA 3N2UA 3EDGA 4WZVA 1PWVA 3I7GA 1CGFA 1C8TA 1XUCA 3LILA 3K7LA 3LK8A 5LABA 3KECA 1KAPP 456CA 1CXVA 4ILWD 3LQ0A 2X3CA 3B2ZA 1GO7P 1YQYA 1IABA 3HBVP 1XFUA 3LUMA 1Y93A 1XM5A 1RMZA 3WV3A 1HFCA 3O2XA 1XFYA 3O64A 3VTGA 1R55A 1G05A 1OO9A 4G0DA 1UMSA 1ZTQA 2MLRA 2RJPA 1MMQA 5D1SA 5B5PA 830CA 1CK7A 1MMBA 2WO8A 1FBLA 3K7NA 2J0TA 3EDIA 4DPEA 1ROSA 2W12A 1FM1A 4AXQA 1DMTA 3HY9A 2W14A 5D1UA 1L6JA 1IADA 1ZP5A 2SRTA 4L19A 1B8YA 2OXWA 1SLNA 4H82A 2J83A 3Q2HA 1QJIA 5I12A 3B92A 4H49A 1ZXCA 3ZVSA 1UTTA 2DW0A 4PKSA 1GKCA 2YIGA 3LJZA 1KUFA 2OXUA 1R1IA 1H71P 4XCTA 1HFSA 1QUAA 3AIGA 2O3EA 1K7IA 1QIBA 2JT6A 1KUKA 1G12A 3LKAA 1ZVXA 2AYKA 1TVIA 3Q2GA 2DW1A 4GWMA 1GO8P 4IJOA 4IUWA 1CGEA 1G9KA 2X3BA 3L0VA 3ZUKA 1XFVA 4GWNA 1JIZA 4AUOA 2ERPA 4XM6A 1CIZA 1GE7A 1BUVM 1QIAA 3ELMA 2WOAA 1OM8A 1A85A 3P24A 1XFXA 1AF0A 1ZS0A 3LIKA 1OM7A 2N8RA 1R54A 1XFWA 3LIRA 1I76A 2XS4A 5D1TA 2JNPA 4L6TA 1HTDA 4CTHA 4JA1A 4H1QA 1BQOA 4EFSA 4WKIA 4L7AA 966CA 1GXDA 4FXQA 3HDBA 1FLSA 3I7IA 2X7MA 1ASTA 4PKQA 2MLSA 1O0QA 1Q3AA 3AYKA 4JIJA 2JIHA 1Y0VA 5I0LA 1A86A 1CGLA 3LJTA 4A7BA 1SMPA 3LQBA 4PKWA 3RTSA 2RJQA 3KMCA 4XM7A 2USNA 4A3WA 1OMJA 1PWUA 3MA2A 1XURA 4DD8A 1USNA 5D7WA 3KEJA 3DPEA 1CQRA 4JPAA 2OY2A 1PWWA 1MMPA 3RTTA 1PWQA 2CLTA 3HYGA 1HV5A 3P1VA 3EWJA 4PKRA 3TVCA 1K7GA 1OS9A 1JAOA 2O36A 2E3XA 3F15A 3LE9A 3V96B 1OM6A 3EDHA 3DNGA 5JMYA 5CUHA 3GBOA 4R3VA 1RM8A 3L0TA 1I1IP 3HBUP 2OVZA 1HOVA 4H3XA 1IAEA 3N2VA 1D7XA 1YOUA 3DSLA 4GR0A 3TT4A 2OZRA 2AIGP 5L79A 3AYUA 4WF6A 1GE6A 1R1HA 3TS4A 1Y8JA 3DL1A 5L7FA 4XBHA 2OW1A 3F18A 1JKYA 2L0RA 2KRJA 2Y6DA 3OHLA 2FV5A 2FV9A 4AIGA 1QICA 5I3MA 1BQQM 1MNCA 3BA0A 4ON1A 1HY7A 3NX7A 3EHXA 1D8MA 1YP1A 5B5OA 2Y6CA 1G4KA 3KWVC 1SATA 4HX3A 1SLMA 1AKLA 1BSWA 1GKDA 4QKZA 3KRYA 4FU4A 4L63A 1ATLA 5D2BA 1UEAA 2OI0A 3F16A 1SRPA 4H76A 1JAQA 2POJA 1YCMA 5I43A 5BOYA 1IAGA 1EUBA 4FVLA 3SHIA 1UTZA 3E8RA 1XAXA 3KHIA 3KMEA 5I4OA 4PKTA 3G5CA 4J4MA 3B8ZA 4GF1A 3VI1A 4FXYP 1KBCA 1OZ9A 1BKCI 4GQLA 1ZXVA 2HU6A 1O0TA 1J7NA 2OY4A 1EAKA 3HB2P 4PKUA 2W0DA 3LGPA 4Q1LA 4I03A 3UVCA 2CKIA 4XM8A 2W15A 2QPJA 3WV1A 3OHOA 4H30A 1S4BP 1OS2A 1JH1A 2MZEA 3ZXHA 1KUHA 2JSDA 2TCLA 3WV2A 1D5JA 4DV8A 1PWPA 3DTKA 2A8HA 2JT5A 1JJ9A 2K9CA 4IN9A 1KUGA 1BKCA 1K7QA 2W13A 1WNIA 2OXZA 1R1JA 4WK7A 2DW2A 1CAQA 1QJJA 5BPAA 4H84A 2XS3A 4GR3A 1C3IA 1BIWA 3LJGA 1UMTA 5I2ZA 3U1RA 3CKIA 1GE5A 1XUDA 3DWBA 2OW0A 3LMCA 4ZR5A 3LEAA 1SU3A 3USNA 2X3AA 2Z2DA 4DF9A 1C7KA 2MZIA 1MMRA 3DTEA 1KUIA 1Z3JA 1BM6A 3F1AA 1XFZA 1AYKA 4I35A 2DDYA 1B3DA 5CZMA 1D8FA 2DDFA
chains in the Genus database with same CATH topology
3F17A 4GUYA 1JK3A 1JIWP 1BKCE 2YB9A 5BOTA 2D1NA 2YUFA 5H8XA 2OVXA 5D3CA 2D1OA 3LUNA 1ND1A 2OW2A 4GR8A 2EROA 3KEKA 1JAPA 2K2GA 1JANA 1BZSA 4JQGA 3G42A 2E2DA 2MZHA 4AYKA 3EDZA 3EHYA 3HY7A 2I47A 2PJTA 1EB6A 1IACA 4G9LA 4JP4A 2OW9A 3TSKA 1DTHA 3DTIA 4H2EA 1G49A 1BUDA 1IAAA 2WO9A 4WKEA 4PKVA 3F19A 1I73A 2V4BA 2ERQA 4HMAA 3HDAP 5CXAA 3DPFA 3N2UA 3EDGA 4WZVA 1PWVA 3I7GA 1CGFA 1C8TA 1XUCA 3LILA 3K7LA 3LK8A 5LABA 3KECA 1KAPP 456CA 1CXVA 4ILWD 3LQ0A 2X3CA 3B2ZA 1GO7P 1YQYA 1IABA 3HBVP 1XFUA 3LUMA 1Y93A 1RMZA 3WV3A 1HFCA 3O2XA 1XFYA 3O64A 3VTGA 1R55A 1G05A 1OO9A 4G0DA 1UMSA 1ZTQA 2MLRA 2RJPA 1MMQA 5D1SA 5B5PA 830CA 1CK7A 1MMBA 2WO8A 1FBLA 3K7NA 2J0TA 3EDIA 4DPEA 1ROSA 2W12A 1FM1A 4AXQA 1DMTA 3HY9A 2W14A 5D1UA 1L6JA 1IADA 1ZP5A 2SRTA 4L19A 1B8YA 2OXWA 1SLNA 4H82A 2J83A 3Q2HA 1QJIA 5I12A 3B92A 4H49A 1ZXCA 3ZVSA 1UTTA 2DW0A 4PKSA 1GKCA 2YIGA 3LJZA 1KUFA 2OXUA 1R1IA 1H71P 4XCTA 1HFSA 1QUAA 3AIGA 2O3EA 1K7IA 1QIBA 2JT6A 1KUKA 1G12A 3LKAA 1ZVXA 2AYKA 3Q2GA 2DW1A 4GWMA 1GO8P 4IJOA 4IUWA 1CGEA 1G9KA 2X3BA 3L0VA 3ZUKA 1XFVA 4GWNA 1JIZA 4AUOA 2ERPA 4XM6A 1CIZA 1GE7A 1BUVM 1QIAA 3ELMA 2WOAA 1OM8A 1A85A 3P24A 1XFXA 1AF0A 1ZS0A 3LIKA 1OM7A 2N8RA 1R54A 1XFWA 3LIRA 1I76A 2XS4A 5D1TA 2JNPA 4L6TA 1HTDA 4CTHA 4JA1A 4H1QA 1BQOA 4EFSA 4WKIA 4L7AA 966CA 1GXDA 4FXQA 3HDBA 1FLSA 3I7IA 2X7MA 1ASTA 4PKQA 2MLSA 1O0QA 1Q3AA 3AYKA 4JIJA 2JIHA 1Y0VA 5I0LA 1A86A 1CGLA 3LJTA 4A7BA 1SMPA 3LQBA 4PKWA 3RTSA 2RJQA 3KMCA 4XM7A 2USNA 4A3WA 1OMJA 1PWUA 3MA2A 1XURA 4DD8A 1USNA 5D7WA 3KEJA 3DPEA 1CQRA 4JPAA 2OY2A 1PWWA 1MMPA 3RTTA 1PWQA 2CLTA 3HYGA 1HV5A 3P1VA 3EWJA 4PKRA 3TVCA 1K7GA 1OS9A 1JAOA 2O36A 2E3XA 3F15A 3LE9A 3V96B 1OM6A 3EDHA 3DNGA 5JMYA 5CUHA 3GBOA 4R3VA 1RM8A 3L0TA 1I1IP 3HBUP 2OVZA 1HOVA 4H3XA 1IAEA 3N2VA 1D7XA 1YOUA 3DSLA 4GR0A 3TT4A 2OZRA 2AIGP 5L79A 3AYUA 4WF6A 1GE6A 1R1HA 3TS4A 1Y8JA 3DL1A 5L7FA 4XBHA 2OW1A 3F18A 1JKYA 2L0RA 2KRJA 2Y6DA 3OHLA 2FV5A 2FV9A 4AIGA 1QICA 5I3MA 1BQQM 1MNCA 3BA0A 4ON1A 1HY7A 3NX7A 3EHXA 1D8MA 1YP1A 5B5OA 2Y6CA 1G4KA 3KWVC 1SATA 4HX3A 1SLMA 1AKLA 1BSWA 1GKDA 4QKZA 3KRYA 4FU4A 4L63A 1ATLA 5D2BA 1UEAA 2OI0A 3F16A 1SRPA 4H76A 1JAQA 2POJA 1YCMA 5I43A 5BOYA 1IAGA 1EUBA 4FVLA 3SHIA 1UTZA 3E8RA 3KHIA 3KMEA 5I4OA 4PKTA 3G5CA 4J4MA 3B8ZA 4GF1A 3VI1A 4FXYP 1KBCA 1BKCI 4GQLA 1ZXVA 2HU6A 1O0TA 1J7NA 2OY4A 1EAKA 3HB2P 4PKUA 2W0DA 3LGPA 4Q1LA 4I03A 3UVCA 2CKIA 4XM8A 2W15A 2QPJA 3WV1A 3OHOA 4H30A 1S4BP 1OS2A 1JH1A 2MZEA 3ZXHA 1KUHA 2JSDA 2TCLA 3WV2A 1D5JA 4DV8A 1PWPA 3DTKA 2A8HA 2JT5A 1JJ9A 2K9CA 4IN9A 1KUGA 1BKCA 1K7QA 2W13A 1WNIA 2OXZA 1R1JA 4WK7A 2DW2A 1CAQA 1QJJA 5BPAA 4H84A 2XS3A 4GR3A 1C3IA 1BIWA 3LJGA 1UMTA 5I2ZA 3U1RA 3CKIA 1GE5A 1XUDA 3DWBA 2OW0A 3LMCA 4ZR5A 3LEAA 1SU3A 3USNA 2X3AA 2Z2DA 4DF9A 1C7KA 2MZIA 1MMRA 3DTEA 1KUIA 1Z3JA 1BM6A 3F1AA 1XFZA 1AYKA 4I35A 2DDYA 1B3DA 5CZMA 1D8FA 2DDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F17 A;  4GUY A;  1JK3 A;  1JIW P;  1BKC E;  2YB9 A;  5BOT A;  2D1N A;  5H8X A;  2OVX A;  5D3C A;  2D1O A;  3LUN A;  1ND1 A;  2OW2 A;  4GR8 A;  2ERO A;  3KEK A;  1JAP A;  2K2G A;  1JAN A;  1BZS A;  4JQG A;  3G42 A;  2E2D A;  2MZH A;  4AYK A;  3EDZ A;  3EHY A;  3HY7 A;  2I47 A;  2PJT A;  1EB6 A;  1IAC A;  4G9L A;  4JP4 A;  2OW9 A;  3TSK A;  1DTH A;  4H2E A;  1G49 A;  1BUD A;  1IAA A;  2WO9 A;  4WKE A;  4PKV A;  3F19 A;  1I73 A;  2V4B A;  2ERQ A;  4HMA A;  3HDA P;  5CXA A;  3DPF A;  3N2U A;  3EDG A;  4WZV A;  1PWV A;  3I7G A;  1CGF A;  1C8T A;  1XUC A;  3LIL A;  3K7L A;  3LK8 A;  5LAB A;  3KEC A;  1KAP P;  456C A;  1CXV A;  4ILW D;  3LQ0 A;  2X3C A;  3B2Z A;  1GO7 P;  1YQY A;  1IAB A;  3HBV P;  1XFU A;  3LUM A;  1Y93 A;  1RMZ A;  3WV3 A;  1HFC A;  3O2X A;  1XFY A;  3O64 A;  3VTG A;  1R55 A;  1G05 A;  1OO9 A;  4G0D A;  1UMS A;  1ZTQ A;  2MLR A;  2RJP A;  1MMQ A;  5D1S A;  5B5P A;  830C A;  1CK7 A;  1MMB A;  2WO8 A;  1FBL A;  3K7N A;  2J0T A;  3EDI A;  4DPE A;  1ROS A;  2W12 A;  1FM1 A;  4AXQ A;  1DMT A;  3HY9 A;  2W14 A;  5D1U A;  1L6J A;  1IAD A;  1ZP5 A;  2SRT A;  4L19 A;  1B8Y A;  2OXW A;  1SLN A;  4H82 A;  2J83 A;  3Q2H A;  1QJI A;  5I12 A;  3B92 A;  4H49 A;  1ZXC A;  3ZVS A;  1UTT A;  2DW0 A;  4PKS A;  1GKC A;  2YIG A;  3LJZ A;  1KUF A;  2OXU A;  1R1I A;  1H71 P;  4XCT A;  1HFS A;  1QUA A;  3AIG A;  2O3E A;  1K7I A;  1QIB A;  2JT6 A;  1KUK A;  1G12 A;  3LKA A;  1ZVX A;  2AYK A;  3Q2G A;  2DW1 A;  4GWM A;  1GO8 P;  4IJO A;  4IUW A;  1CGE A;  1G9K A;  2X3B A;  3L0V A;  3ZUK A;  1XFV A;  4GWN A;  1JIZ A;  4AUO A;  2ERP A;  4XM6 A;  1CIZ A;  1GE7 A;  1BUV M;  1QIA A;  3ELM A;  2WOA A;  1OM8 A;  1A85 A;  3P24 A;  1XFX A;  1AF0 A;  1ZS0 A;  3LIK A;  1OM7 A;  2N8R A;  1R54 A;  1XFW A;  3LIR A;  1I76 A;  2XS4 A;  5D1T A;  2JNP A;  4L6T A;  1HTD A;  4CTH A;  4JA1 A;  4H1Q A;  1BQO A;  4EFS A;  4WKI A;  966C A;  1GXD A;  4FXQ A;  3HDB A;  1FLS A;  3I7I A;  2X7M A;  1AST A;  4PKQ A;  2MLS A;  1O0Q A;  1Q3A A;  3AYK A;  4JIJ A;  2JIH A;  1Y0V A;  5I0L A;  1A86 A;  1CGL A;  3LJT A;  4A7B A;  1SMP A;  3LQB A;  4PKW A;  3RTS A;  2RJQ A;  3KMC A;  4XM7 A;  2USN A;  4A3W A;  1OMJ A;  1PWU A;  3MA2 A;  1XUR A;  4DD8 A;  1USN A;  5D7W A;  3KEJ A;  3DPE A;  1CQR A;  4JPA A;  2OY2 A;  1PWW A;  1MMP A;  3RTT A;  1PWQ A;  2CLT A;  3HYG A;  1HV5 A;  3P1V A;  3EWJ A;  4PKR A;  3TVC A;  1K7G A;  1OS9 A;  1JAO A;  2O36 A;  2E3X A;  3F15 A;  3LE9 A;  3V96 B;  1OM6 A;  3EDH A;  3DNG A;  5JMY A;  5CUH A;  3GBO A;  4R3V A;  1RM8 A;  3L0T A;  1I1I P;  3HBU P;  2OVZ A;  1HOV A;  4H3X A;  1IAE A;  3N2V A;  1D7X A;  1YOU A;  3DSL A;  4GR0 A;  3TT4 A;  2OZR A;  2AIG P;  5L79 A;  3AYU A;  4WF6 A;  1GE6 A;  1R1H A;  3TS4 A;  1Y8J A;  3DL1 A;  5L7F A;  4XBH A;  2OW1 A;  3F18 A;  1JKY A;  2L0R A;  2KRJ A;  2Y6D A;  3OHL A;  2FV5 A;  2FV9 A;  4AIG A;  1QIC A;  5I3M A;  1BQQ M;  1MNC A;  3BA0 A;  4ON1 A;  1HY7 A;  3NX7 A;  3EHX A;  1D8M A;  1YP1 A;  5B5O A;  2Y6C A;  1G4K A;  3KWV C;  1SAT A;  4HX3 A;  1SLM A;  1AKL A;  1BSW A;  1GKD A;  4QKZ A;  3KRY A;  4FU4 A;  4L63 A;  1ATL A;  5D2B A;  1UEA A;  2OI0 A;  3F16 A;  1SRP A;  4H76 A;  1JAQ A;  2POJ A;  1YCM A;  5I43 A;  5BOY A;  1IAG A;  1EUB A;  4FVL A;  3SHI A;  1UTZ A;  3E8R A;  3KHI A;  3KME A;  5I4O A;  4PKT A;  3G5C A;  4J4M A;  3B8Z A;  4GF1 A;  3VI1 A;  4FXY P;  1KBC A;  1BKC I;  4GQL A;  1ZXV A;  2HU6 A;  1O0T A;  1J7N A;  2OY4 A;  1EAK A;  3HB2 P;  4PKU A;  2W0D A;  3LGP A;  4Q1L A;  4I03 A;  3UVC A;  2CKI A;  4XM8 A;  2W15 A;  2QPJ A;  3WV1 A;  3OHO A;  4H30 A;  1S4B P;  1OS2 A;  1JH1 A;  2MZE A;  3ZXH A;  1KUH A;  2JSD A;  2TCL A;  3WV2 A;  1D5J A;  4DV8 A;  1PWP A;  2A8H A;  2JT5 A;  1JJ9 A;  2K9C A;  4IN9 A;  1KUG A;  1BKC A;  1K7Q A;  2W13 A;  1WNI A;  2OXZ A;  1R1J A;  4WK7 A;  2DW2 A;  1CAQ A;  1QJJ A;  5BPA A;  4H84 A;  2XS3 A;  4GR3 A;  1C3I A;  1BIW A;  3LJG A;  1UMT A;  5I2Z A;  3U1R A;  3CKI A;  1GE5 A;  1XUD A;  3DWB A;  2OW0 A;  3LMC A;  4ZR5 A;  3LEA A;  1SU3 A;  3USN A;  2X3A A;  2Z2D A;  4DF9 A;  1C7K A;  2MZI A;  1MMR A;  1KUI A;  1Z3J A;  1BM6 A;  3F1A A;  1XFZ A;  1AYK A;  4I35 A;  2DDY A;  1B3D A;  5CZM A;  1D8F A;  2DDF A; 
#chains in the Genus database with same CATH topology
 3F17 A;  4GUY A;  1JK3 A;  1JIW P;  1BKC E;  2YB9 A;  5BOT A;  2D1N A;  2YUF A;  5H8X A;  2OVX A;  5D3C A;  2D1O A;  3LUN A;  1ND1 A;  2OW2 A;  4GR8 A;  2ERO A;  3KEK A;  1JAP A;  2K2G A;  1JAN A;  1BZS A;  4JQG A;  3G42 A;  2E2D A;  2MZH A;  4AYK A;  3EDZ A;  3EHY A;  3HY7 A;  2I47 A;  2PJT A;  1EB6 A;  1IAC A;  4G9L A;  4JP4 A;  2OW9 A;  3TSK A;  1DTH A;  3DTI A;  4H2E A;  1G49 A;  1BUD A;  1IAA A;  2WO9 A;  4WKE A;  4PKV A;  3F19 A;  1I73 A;  2V4B A;  2ERQ A;  4HMA A;  3HDA P;  5CXA A;  3DPF A;  3N2U A;  3EDG A;  4WZV A;  1PWV A;  3I7G A;  1CGF A;  1C8T A;  1XUC A;  3LIL A;  3K7L A;  3LK8 A;  5LAB A;  3KEC A;  1KAP P;  456C A;  1CXV A;  4ILW D;  3LQ0 A;  2X3C A;  3B2Z A;  1GO7 P;  1YQY A;  1IAB A;  3HBV P;  1XFU A;  3LUM A;  1Y93 A;  1XM5 A;  1RMZ A;  3WV3 A;  1HFC A;  3O2X A;  1XFY A;  3O64 A;  3VTG A;  1R55 A;  1G05 A;  1OO9 A;  4G0D A;  1UMS A;  1ZTQ A;  2MLR A;  2RJP A;  1MMQ A;  5D1S A;  5B5P A;  830C A;  1CK7 A;  1MMB A;  2WO8 A;  1FBL A;  3K7N A;  2J0T A;  3EDI A;  4DPE A;  1ROS A;  2W12 A;  1FM1 A;  4AXQ A;  1DMT A;  3HY9 A;  2W14 A;  5D1U A;  1L6J A;  1IAD A;  1ZP5 A;  2SRT A;  4L19 A;  1B8Y A;  2OXW A;  1SLN A;  4H82 A;  2J83 A;  3Q2H A;  1QJI A;  5I12 A;  3B92 A;  4H49 A;  1ZXC A;  3ZVS A;  1UTT A;  2DW0 A;  4PKS A;  1GKC A;  2YIG A;  3LJZ A;  1KUF A;  2OXU A;  1R1I A;  1H71 P;  4XCT A;  1HFS A;  1QUA A;  3AIG A;  2O3E A;  1K7I A;  1QIB A;  2JT6 A;  1KUK A;  1G12 A;  3LKA A;  1ZVX A;  2AYK A;  1TVI A;  3Q2G A;  2DW1 A;  4GWM A;  1GO8 P;  4IJO A;  4IUW A;  1CGE A;  1G9K A;  2X3B A;  3L0V A;  3ZUK A;  1XFV A;  4GWN A;  1JIZ A;  4AUO A;  2ERP A;  4XM6 A;  1CIZ A;  1GE7 A;  1BUV M;  1QIA A;  3ELM A;  2WOA A;  1OM8 A;  1A85 A;  3P24 A;  1XFX A;  1AF0 A;  1ZS0 A;  3LIK A;  1OM7 A;  2N8R A;  1R54 A;  1XFW A;  3LIR A;  1I76 A;  2XS4 A;  5D1T A;  2JNP A;  4L6T A;  1HTD A;  4CTH A;  4JA1 A;  4H1Q A;  1BQO A;  4EFS A;  4WKI A;  4L7A A;  966C A;  1GXD A;  4FXQ A;  3HDB A;  1FLS A;  3I7I A;  2X7M A;  1AST A;  4PKQ A;  2MLS A;  1O0Q A;  1Q3A A;  3AYK A;  4JIJ A;  2JIH A;  1Y0V A;  5I0L A;  1A86 A;  1CGL A;  3LJT A;  4A7B A;  1SMP A;  3LQB A;  4PKW A;  3RTS A;  2RJQ A;  3KMC A;  4XM7 A;  2USN A;  4A3W A;  1OMJ A;  1PWU A;  3MA2 A;  1XUR A;  4DD8 A;  1USN A;  5D7W A;  3KEJ A;  3DPE A;  1CQR A;  4JPA A;  2OY2 A;  1PWW A;  1MMP A;  3RTT A;  1PWQ A;  2CLT A;  3HYG A;  1HV5 A;  3P1V A;  3EWJ A;  4PKR A;  3TVC A;  1K7G A;  1OS9 A;  1JAO A;  2O36 A;  2E3X A;  3F15 A;  3LE9 A;  3V96 B;  1OM6 A;  3EDH A;  3DNG A;  5JMY A;  5CUH A;  3GBO A;  4R3V A;  1RM8 A;  3L0T A;  1I1I P;  3HBU P;  2OVZ A;  1HOV A;  4H3X A;  1IAE A;  3N2V A;  1D7X A;  1YOU A;  3DSL A;  4GR0 A;  3TT4 A;  2OZR A;  2AIG P;  5L79 A;  3AYU A;  4WF6 A;  1GE6 A;  1R1H A;  3TS4 A;  1Y8J A;  3DL1 A;  5L7F A;  4XBH A;  2OW1 A;  3F18 A;  1JKY A;  2L0R A;  2KRJ A;  2Y6D A;  3OHL A;  2FV5 A;  2FV9 A;  4AIG A;  1QIC A;  5I3M A;  1BQQ M;  1MNC A;  3BA0 A;  4ON1 A;  1HY7 A;  3NX7 A;  3EHX A;  1D8M A;  1YP1 A;  5B5O A;  2Y6C A;  1G4K A;  3KWV C;  1SAT A;  4HX3 A;  1SLM A;  1AKL A;  1BSW A;  1GKD A;  4QKZ A;  3KRY A;  4FU4 A;  4L63 A;  1ATL A;  5D2B A;  1UEA A;  2OI0 A;  3F16 A;  1SRP A;  4H76 A;  1JAQ A;  2POJ A;  1YCM A;  5I43 A;  5BOY A;  1IAG A;  1EUB A;  4FVL A;  3SHI A;  1UTZ A;  3E8R A;  1XAX A;  3KHI A;  3KME A;  5I4O A;  4PKT A;  3G5C A;  4J4M A;  3B8Z A;  4GF1 A;  3VI1 A;  4FXY P;  1KBC A;  1OZ9 A;  1BKC I;  4GQL A;  1ZXV A;  2HU6 A;  1O0T A;  1J7N A;  2OY4 A;  1EAK A;  3HB2 P;  4PKU A;  2W0D A;  3LGP A;  4Q1L A;  4I03 A;  3UVC A;  2CKI A;  4XM8 A;  2W15 A;  2QPJ A;  3WV1 A;  3OHO A;  4H30 A;  1S4B P;  1OS2 A;  1JH1 A;  2MZE A;  3ZXH A;  1KUH A;  2JSD A;  2TCL A;  3WV2 A;  1D5J A;  4DV8 A;  1PWP A;  3DTK A;  2A8H A;  2JT5 A;  1JJ9 A;  2K9C A;  4IN9 A;  1KUG A;  1BKC A;  1K7Q A;  2W13 A;  1WNI A;  2OXZ A;  1R1J A;  4WK7 A;  2DW2 A;  1CAQ A;  1QJJ A;  5BPA A;  4H84 A;  2XS3 A;  4GR3 A;  1C3I A;  1BIW A;  3LJG A;  1UMT A;  5I2Z A;  3U1R A;  3CKI A;  1GE5 A;  1XUD A;  3DWB A;  2OW0 A;  3LMC A;  4ZR5 A;  3LEA A;  1SU3 A;  3USN A;  2X3A A;  2Z2D A;  4DF9 A;  1C7K A;  2MZI A;  1MMR A;  3DTE A;  1KUI A;  1Z3J A;  1BM6 A;  3F1A A;  1XFZ A;  1AYK A;  4I35 A;  2DDY A;  1B3D A;  5CZM A;  1D8F A;  2DDF A; 
#chains in the Genus database with same CATH homology
 3F17 A;  4GUY A;  1JK3 A;  1JIW P;  1BKC E;  2YB9 A;  5BOT A;  2D1N A;  2YUF A;  5H8X A;  2OVX A;  5D3C A;  2D1O A;  3LUN A;  1ND1 A;  2OW2 A;  4GR8 A;  2ERO A;  3KEK A;  1JAP A;  2K2G A;  1JAN A;  1BZS A;  4JQG A;  3G42 A;  2E2D A;  2MZH A;  4AYK A;  3EDZ A;  3EHY A;  3HY7 A;  2I47 A;  2PJT A;  1EB6 A;  1IAC A;  4G9L A;  4JP4 A;  2OW9 A;  3TSK A;  1DTH A;  3DTI A;  4H2E A;  1G49 A;  1BUD A;  1IAA A;  2WO9 A;  4WKE A;  4PKV A;  3F19 A;  1I73 A;  2V4B A;  2ERQ A;  4HMA A;  3HDA P;  5CXA A;  3DPF A;  3N2U A;  3EDG A;  4WZV A;  1PWV A;  3I7G A;  1CGF A;  1C8T A;  1XUC A;  3LIL A;  3K7L A;  3LK8 A;  5LAB A;  3KEC A;  1KAP P;  456C A;  1CXV A;  4ILW D;  3LQ0 A;  2X3C A;  3B2Z A;  1GO7 P;  1YQY A;  1IAB A;  3HBV P;  1XFU A;  3LUM A;  1Y93 A;  1RMZ A;  3WV3 A;  1HFC A;  3O2X A;  1XFY A;  3O64 A;  3VTG A;  1R55 A;  1G05 A;  1OO9 A;  4G0D A;  1UMS A;  1ZTQ A;  2MLR A;  2RJP A;  1MMQ A;  5D1S A;  5B5P A;  830C A;  1CK7 A;  1MMB A;  2WO8 A;  1FBL A;  3K7N A;  2J0T A;  3EDI A;  4DPE A;  1ROS A;  2W12 A;  1FM1 A;  4AXQ A;  1DMT A;  3HY9 A;  2W14 A;  5D1U A;  1L6J A;  1IAD A;  1ZP5 A;  2SRT A;  4L19 A;  1B8Y A;  2OXW A;  1SLN A;  4H82 A;  2J83 A;  3Q2H A;  1QJI A;  5I12 A;  3B92 A;  4H49 A;  1ZXC A;  3ZVS A;  1UTT A;  2DW0 A;  4PKS A;  1GKC A;  2YIG A;  3LJZ A;  1KUF A;  2OXU A;  1R1I A;  1H71 P;  4XCT A;  1HFS A;  1QUA A;  3AIG A;  2O3E A;  1K7I A;  1QIB A;  2JT6 A;  1KUK A;  1G12 A;  3LKA A;  1ZVX A;  2AYK A;  3Q2G A;  2DW1 A;  4GWM A;  1GO8 P;  4IJO A;  4IUW A;  1CGE A;  1G9K A;  2X3B A;  3L0V A;  3ZUK A;  1XFV A;  4GWN A;  1JIZ A;  4AUO A;  2ERP A;  4XM6 A;  1CIZ A;  1GE7 A;  1BUV M;  1QIA A;  3ELM A;  2WOA A;  1OM8 A;  1A85 A;  3P24 A;  1XFX A;  1AF0 A;  1ZS0 A;  3LIK A;  1OM7 A;  2N8R A;  1R54 A;  1XFW A;  3LIR A;  1I76 A;  2XS4 A;  5D1T A;  2JNP A;  4L6T A;  1HTD A;  4CTH A;  4JA1 A;  4H1Q A;  1BQO A;  4EFS A;  4WKI A;  4L7A A;  966C A;  1GXD A;  4FXQ A;  3HDB A;  1FLS A;  3I7I A;  2X7M A;  1AST A;  4PKQ A;  2MLS A;  1O0Q A;  1Q3A A;  3AYK A;  4JIJ A;  2JIH A;  1Y0V A;  5I0L A;  1A86 A;  1CGL A;  3LJT A;  4A7B A;  1SMP A;  3LQB A;  4PKW A;  3RTS A;  2RJQ A;  3KMC A;  4XM7 A;  2USN A;  4A3W A;  1OMJ A;  1PWU A;  3MA2 A;  1XUR A;  4DD8 A;  1USN A;  5D7W A;  3KEJ A;  3DPE A;  1CQR A;  4JPA A;  2OY2 A;  1PWW A;  1MMP A;  3RTT A;  1PWQ A;  2CLT A;  3HYG A;  1HV5 A;  3P1V A;  3EWJ A;  4PKR A;  3TVC A;  1K7G A;  1OS9 A;  1JAO A;  2O36 A;  2E3X A;  3F15 A;  3LE9 A;  3V96 B;  1OM6 A;  3EDH A;  3DNG A;  5JMY A;  5CUH A;  3GBO A;  4R3V A;  1RM8 A;  3L0T A;  1I1I P;  3HBU P;  2OVZ A;  1HOV A;  4H3X A;  1IAE A;  3N2V A;  1D7X A;  1YOU A;  3DSL A;  4GR0 A;  3TT4 A;  2OZR A;  2AIG P;  5L79 A;  3AYU A;  4WF6 A;  1GE6 A;  1R1H A;  3TS4 A;  1Y8J A;  3DL1 A;  5L7F A;  4XBH A;  2OW1 A;  3F18 A;  1JKY A;  2L0R A;  2KRJ A;  2Y6D A;  3OHL A;  2FV5 A;  2FV9 A;  4AIG A;  1QIC A;  5I3M A;  1BQQ M;  1MNC A;  3BA0 A;  4ON1 A;  1HY7 A;  3NX7 A;  3EHX A;  1D8M A;  1YP1 A;  5B5O A;  2Y6C A;  1G4K A;  3KWV C;  1SAT A;  4HX3 A;  1SLM A;  1AKL A;  1BSW A;  1GKD A;  4QKZ A;  3KRY A;  4FU4 A;  4L63 A;  1ATL A;  5D2B A;  1UEA A;  2OI0 A;  3F16 A;  1SRP A;  4H76 A;  1JAQ A;  2POJ A;  1YCM A;  5I43 A;  5BOY A;  1IAG A;  1EUB A;  4FVL A;  3SHI A;  1UTZ A;  3E8R A;  3KHI A;  3KME A;  5I4O A;  4PKT A;  3G5C A;  4J4M A;  3B8Z A;  4GF1 A;  3VI1 A;  4FXY P;  1KBC A;  1BKC I;  4GQL A;  1ZXV A;  2HU6 A;  1O0T A;  1J7N A;  2OY4 A;  1EAK A;  3HB2 P;  4PKU A;  2W0D A;  3LGP A;  4Q1L A;  4I03 A;  3UVC A;  2CKI A;  4XM8 A;  2W15 A;  2QPJ A;  3WV1 A;  3OHO A;  4H30 A;  1S4B P;  1OS2 A;  1JH1 A;  2MZE A;  3ZXH A;  1KUH A;  2JSD A;  2TCL A;  3WV2 A;  1D5J A;  4DV8 A;  1PWP A;  3DTK A;  2A8H A;  2JT5 A;  1JJ9 A;  2K9C A;  4IN9 A;  1KUG A;  1BKC A;  1K7Q A;  2W13 A;  1WNI A;  2OXZ A;  1R1J A;  4WK7 A;  2DW2 A;  1CAQ A;  1QJJ A;  5BPA A;  4H84 A;  2XS3 A;  4GR3 A;  1C3I A;  1BIW A;  3LJG A;  1UMT A;  5I2Z A;  3U1R A;  3CKI A;  1GE5 A;  1XUD A;  3DWB A;  2OW0 A;  3LMC A;  4ZR5 A;  3LEA A;  1SU3 A;  3USN A;  2X3A A;  2Z2D A;  4DF9 A;  1C7K A;  2MZI A;  1MMR A;  3DTE A;  1KUI A;  1Z3J A;  1BM6 A;  3F1A A;  1XFZ A;  1AYK A;  4I35 A;  2DDY A;  1B3D A;  5CZM A;  1D8F A;  2DDF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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