3L50A

The crystal structure of human glia maturation factor, gamma (gmfg)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
136
structure length
136
Chain Sequence
SMVCEVDPELTEKLRKFRFRKETDNAAIIMKVDKDRQMVVLEEEFQNISPEELKMELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRTTDDLTEAWLQEKLSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human Glia Maturation Factor, Gamma (GMFG)
rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords Glia maturation factor gamma
total genus 35
structure length 136
sequence length 136
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3l50A00
1D4XG 1RGIG 2HD7A 1P8ZG 3EGXA 2FH2A 2VILA 3A5MS 2NUPB 4CBXG 2VIKA 2KVKA 1EQYS 2VACA 1AK7A 3A5NS 1TVJA 1Q8GA 2I2QA 3FFNA 1PD0A 1WFSA 3FG7A 1VFQA 1WM4A 1C0FS 2L72A 4CBWG 5KYWA 1COFA 5HVKB 5KYYB 1V6FA 2NUTA 3DAWB 5KYUA 2FH1A 3EGXB 1YAGG 4PKIG 3CJCG 2LJ8A 2FF3A 1NLVG 1SVYA 4CBUG 1QPVA 2XF1A 3FG6A 2D8BA 3Q2BA 2MV2A 2FF6G 3L50A 3A5OS 5KYWB 3CIPG 3EH2A 3CJBG 3EG9A 2NUTB 1DEJS 4PKGG 3FFKA 1M2VA 5KYUB 4BEX1 1PCXA 1T3XA 5FAFA 4S10C 1M4JA 1AK6A 1NM1G 3EFOA 1JHWA 1C0GS 5HVKD 1H1VG 1CFYA 4JD2H 1NMDG 1X67A 4LIZA 4KEDA 3EG9B 1UDMA 1P8XA 1M2VB 2MOTA 1F7SA 4KEEA 1M2OA 5FAEA 2W0IA 4PKHB 3A5LS 2MP4A 5KYXA 3EGDA 2FH4A 1SVQA 5KYNA 5L6WC 3EFOB 1T2LA 1VKKA 3EH1A 5A1MA 4Z94G 2FGHA 3CI5G 1SVRA 1KCQA 5DD2A 1T3YA 2FH3A 1PD1A 1WNJA 1T44G 1MDUA 2QTVA 1J72A 1ESVS 2LXXA 5KYXB 4KEFA 1NPHA 2NUPA 3EGDB 3TU5B 1YVNG 2LLFA 1Q8XA 1TMWA 1AHQA 1D0NA 1HQZ1 1CNUA 5IVUA 2XFAA 5KYYA
chains in the Genus database with same CATH superfamily
1D4XG 1RGIG 2HD7A 1P8ZG 3EGXA 2FH2A 2VILA 3A5MS 2NUPB 4CBXG 2VIKA 2KVKA 1EQYS 2VACA 1AK7A 3A5NS 1TVJA 1Q8GA 2I2QA 3FFNA 1PD0A 1WFSA 3FG7A 1VFQA 1WM4A 1C0FS 2L72A 4CBWG 5KYWA 1COFA 5HVKB 5KYYB 1V6FA 2NUTA 3DAWB 5KYUA 2FH1A 3EGXB 1YAGG 4PKIG 3CJCG 3DA7A 2LJ8A 2FF3A 1NLVG 1SVYA 4CBUG 1QPVA 2XF1A 3FG6A 2D8BA 3Q2BA 2MV2A 2FF6G 3L50A 3A5OS 5KYWB 3CIPG 3EH2A 3CJBG 3EG9A 2NUTB 1DEJS 4PKGG 3FFKA 1M2VA 5KYUB 4BEX1 1PCXA 1T3XA 5FAFA 4S10C 1M4JA 1AK6A 1NM1G 3EFOA 1JHWA 1C0GS 5HVKD 1H1VG 1CFYA 4JD2H 1NMDG 1X67A 4LIZA 4KEDA 3EG9B 1UDMA 1P8XA 1M2VB 2MOTA 1F7SA 4KEEA 1M2OA 5FAEA 2W0IA 4PKHB 3A5LS 2MP4A 5KYXA 3EGDA 2FH4A 1SVQA 5KYNA 5L6WC 3EFOB 1T2LA 1VKKA 3EH1A 5A1MA 4Z94G 2FGHA 3CI5G 1SVRA 1KCQA 5DD2A 1T3YA 2FH3A 1PD1A 1WNJA 1T44G 1MDUA 2QTVA 1J72A 1ESVS 2LXXA 5KYXB 4KEFA 1NPHA 2NUPA 3EGDB 3TU5B 1YVNG 2LLFA 1Q8XA 1TMWA 1AHQA 1D0NA 1HQZ1 1CNUA 5IVUA 2XFAA 5KYYA
chains in the Genus database with same CATH topology
1D4XG 1RGIG 2HD7A 1P8ZG 3EGXA 2FH2A 2VILA 3A5MS 2NUPB 4CBXG 2VIKA 2KVKA 1EQYS 2VACA 1AK7A 3A5NS 1TVJA 1Q8GA 2I2QA 3FFNA 1PD0A 1WFSA 3FG7A 1VFQA 1WM4A 1C0FS 2L72A 4CBWG 5KYWA 1COFA 5HVKB 5KYYB 1V6FA 2NUTA 3DAWB 5KYUA 2FH1A 3EGXB 1YAGG 4PKIG 3CJCG 3DA7A 2LJ8A 2FF3A 1NLVG 1SVYA 4CBUG 1QPVA 2XF1A 3FG6A 2D8BA 3Q2BA 2MV2A 2FF6G 3L50A 3A5OS 5KYWB 3CIPG 3EH2A 3CJBG 3EG9A 2NUTB 1DEJS 4PKGG 3FFKA 1M2VA 5KYUB 4BEX1 1PCXA 1T3XA 5FAFA 4S10C 1M4JA 1AK6A 1NM1G 3EFOA 1JHWA 1C0GS 5HVKD 1H1VG 1CFYA 4JD2H 1NMDG 1X67A 4LIZA 4KEDA 3EG9B 1UDMA 1P8XA 1M2VB 2MOTA 1F7SA 4KEEA 1M2OA 5FAEA 2W0IA 4PKHB 3A5LS 2MP4A 5KYXA 3EGDA 2FH4A 1SVQA 5KYNA 5L6WC 3EFOB 1T2LA 1VKKA 3EH1A 5A1MA 4Z94G 2FGHA 3CI5G 1SVRA 1KCQA 5DD2A 1T3YA 2FH3A 1PD1A 1WNJA 1T44G 1MDUA 2QTVA 1J72A 1ESVS 2LXXA 5KYXB 4KEFA 1NPHA 2NUPA 3EGDB 3TU5B 1YVNG 2LLFA 1Q8XA 1TMWA 1AHQA 1D0NA 1HQZ1 1CNUA 5IVUA 2XFAA 5KYYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D4X G;  1RGI G;  2HD7 A;  1P8Z G;  3EGX A;  2FH2 A;  2VIL A;  3A5M S;  2NUP B;  4CBX G;  2VIK A;  2KVK A;  1EQY S;  2VAC A;  1AK7 A;  3A5N S;  1TVJ A;  1Q8G A;  2I2Q A;  3FFN A;  1PD0 A;  1WFS A;  3FG7 A;  1VFQ A;  1WM4 A;  1C0F S;  2L72 A;  4CBW G;  5KYW A;  1COF A;  5HVK B;  5KYY B;  1V6F A;  2NUT A;  3DAW B;  5KYU A;  2FH1 A;  3EGX B;  1YAG G;  4PKI G;  3CJC G;  2LJ8 A;  2FF3 A;  1NLV G;  1SVY A;  4CBU G;  1QPV A;  2XF1 A;  3FG6 A;  2D8B A;  3Q2B A;  2MV2 A;  2FF6 G;  3L50 A;  3A5O S;  5KYW B;  3CIP G;  3EH2 A;  3CJB G;  3EG9 A;  2NUT B;  1DEJ S;  4PKG G;  3FFK A;  1M2V A;  5KYU B;  4BEX 1;  1PCX A;  1T3X A;  5FAF A;  4S10 C;  1M4J A;  1AK6 A;  1NM1 G;  3EFO A;  1JHW A;  1C0G S;  5HVK D;  1H1V G;  1CFY A;  4JD2 H;  1NMD G;  1X67 A;  4LIZ A;  4KED A;  3EG9 B;  1UDM A;  1P8X A;  1M2V B;  2MOT A;  1F7S A;  4KEE A;  1M2O A;  5FAE A;  2W0I A;  4PKH B;  3A5L S;  2MP4 A;  5KYX A;  3EGD A;  2FH4 A;  1SVQ A;  5KYN A;  5L6W C;  3EFO B;  1T2L A;  1VKK A;  3EH1 A;  5A1M A;  4Z94 G;  2FGH A;  3CI5 G;  1SVR A;  1KCQ A;  5DD2 A;  1T3Y A;  2FH3 A;  1PD1 A;  1WNJ A;  1T44 G;  1MDU A;  2QTV A;  1J72 A;  1ESV S;  2LXX A;  5KYX B;  4KEF A;  1NPH A;  2NUP A;  3EGD B;  3TU5 B;  1YVN G;  2LLF A;  1Q8X A;  1TMW A;  1AHQ A;  1D0N A;  1HQZ 1;  1CNU A;  5IVU A;  2XFA A;  5KYY A; 
#chains in the Genus database with same CATH topology
 1D4X G;  1RGI G;  2HD7 A;  1P8Z G;  3EGX A;  2FH2 A;  2VIL A;  3A5M S;  2NUP B;  4CBX G;  2VIK A;  2KVK A;  1EQY S;  2VAC A;  1AK7 A;  3A5N S;  1TVJ A;  1Q8G A;  2I2Q A;  3FFN A;  1PD0 A;  1WFS A;  3FG7 A;  1VFQ A;  1WM4 A;  1C0F S;  2L72 A;  4CBW G;  5KYW A;  1COF A;  5HVK B;  5KYY B;  1V6F A;  2NUT A;  3DAW B;  5KYU A;  2FH1 A;  3EGX B;  1YAG G;  4PKI G;  3CJC G;  3DA7 A;  2LJ8 A;  2FF3 A;  1NLV G;  1SVY A;  4CBU G;  1QPV A;  2XF1 A;  3FG6 A;  2D8B A;  3Q2B A;  2MV2 A;  2FF6 G;  3L50 A;  3A5O S;  5KYW B;  3CIP G;  3EH2 A;  3CJB G;  3EG9 A;  2NUT B;  1DEJ S;  4PKG G;  3FFK A;  1M2V A;  5KYU B;  4BEX 1;  1PCX A;  1T3X A;  5FAF A;  4S10 C;  1M4J A;  1AK6 A;  1NM1 G;  3EFO A;  1JHW A;  1C0G S;  5HVK D;  1H1V G;  1CFY A;  4JD2 H;  1NMD G;  1X67 A;  4LIZ A;  4KED A;  3EG9 B;  1UDM A;  1P8X A;  1M2V B;  2MOT A;  1F7S A;  4KEE A;  1M2O A;  5FAE A;  2W0I A;  4PKH B;  3A5L S;  2MP4 A;  5KYX A;  3EGD A;  2FH4 A;  1SVQ A;  5KYN A;  5L6W C;  3EFO B;  1T2L A;  1VKK A;  3EH1 A;  5A1M A;  4Z94 G;  2FGH A;  3CI5 G;  1SVR A;  1KCQ A;  5DD2 A;  1T3Y A;  2FH3 A;  1PD1 A;  1WNJ A;  1T44 G;  1MDU A;  2QTV A;  1J72 A;  1ESV S;  2LXX A;  5KYX B;  4KEF A;  1NPH A;  2NUP A;  3EGD B;  3TU5 B;  1YVN G;  2LLF A;  1Q8X A;  1TMW A;  1AHQ A;  1D0N A;  1HQZ 1;  1CNU A;  5IVU A;  2XFA A;  5KYY A; 
#chains in the Genus database with same CATH homology
 1D4X G;  1RGI G;  2HD7 A;  1P8Z G;  3EGX A;  2FH2 A;  2VIL A;  3A5M S;  2NUP B;  4CBX G;  2VIK A;  2KVK A;  1EQY S;  2VAC A;  1AK7 A;  3A5N S;  1TVJ A;  1Q8G A;  2I2Q A;  3FFN A;  1PD0 A;  1WFS A;  3FG7 A;  1VFQ A;  1WM4 A;  1C0F S;  2L72 A;  4CBW G;  5KYW A;  1COF A;  5HVK B;  5KYY B;  1V6F A;  2NUT A;  3DAW B;  5KYU A;  2FH1 A;  3EGX B;  1YAG G;  4PKI G;  3CJC G;  3DA7 A;  2LJ8 A;  2FF3 A;  1NLV G;  1SVY A;  4CBU G;  1QPV A;  2XF1 A;  3FG6 A;  2D8B A;  3Q2B A;  2MV2 A;  2FF6 G;  3L50 A;  3A5O S;  5KYW B;  3CIP G;  3EH2 A;  3CJB G;  3EG9 A;  2NUT B;  1DEJ S;  4PKG G;  3FFK A;  1M2V A;  5KYU B;  4BEX 1;  1PCX A;  1T3X A;  5FAF A;  4S10 C;  1M4J A;  1AK6 A;  1NM1 G;  3EFO A;  1JHW A;  1C0G S;  5HVK D;  1H1V G;  1CFY A;  4JD2 H;  1NMD G;  1X67 A;  4LIZ A;  4KED A;  3EG9 B;  1UDM A;  1P8X A;  1M2V B;  2MOT A;  1F7S A;  4KEE A;  1M2O A;  5FAE A;  2W0I A;  4PKH B;  3A5L S;  2MP4 A;  5KYX A;  3EGD A;  2FH4 A;  1SVQ A;  5KYN A;  5L6W C;  3EFO B;  1T2L A;  1VKK A;  3EH1 A;  5A1M A;  4Z94 G;  2FGH A;  3CI5 G;  1SVR A;  1KCQ A;  5DD2 A;  1T3Y A;  2FH3 A;  1PD1 A;  1WNJ A;  1T44 G;  1MDU A;  2QTV A;  1J72 A;  1ESV S;  2LXX A;  5KYX B;  4KEF A;  1NPH A;  2NUP A;  3EGD B;  3TU5 B;  1YVN G;  2LLF A;  1Q8X A;  1TMW A;  1AHQ A;  1D0N A;  1HQZ 1;  1CNU A;  5IVU A;  2XFA A;  5KYY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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