3LEAA

Crystal structure of the catalytic domain of tace with isoindolinone-biphenyl-hydantoin inhibitor
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
258
structure length
258
Chain Sequence
DPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTAWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYGGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSQCSKQSIYKTIESKAQECFQERS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Disintegrin and metalloproteinase domain-containing protein
publication title Biaryl substituted hydantoin compounds as TACE inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 84
structure length 258
sequence length 258
chains with identical sequence B
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2010-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13688 Reprolysin_5 Metallo-peptidase family M12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3leaA00
1ZS0A 4XBHA 5I43A 4GR3A 3EDZA 1KUFA 1XFXA 1SLMA 1Y93A 2SRTA 2X3CA 3WV3A 1PWPA 1GE6A 2OVZA 1CGFA 1UTZA 3RTTA 4JA1A 1BSWA 2OVXA 2W13A 1JANA 2WOAA 3L0VA 2OW0A 3B8ZA 1ZTQA 1BKCA 5I12A 4H1QA 4PKTA 2D1OA 1Y0VA 1QIBA 1R54A 4J4MA 3N2VA 1PWUA 3LUNA 3TS4A 3LJGA 4I35A 5LABA 4PKWA 1SATA 3OHOA 1GO7P 3KMCA 3LEAA 3RTSA 3LMCA 4A7BA 3DPFA 3F18A 1D7XA 3Q2GA 2EROA 1Z3JA 2X7MA 3HDBA 1PWWA 4FXQA 3EWJA 1QJJA 2KRJA 3UVCA 1K7IA 1USNA 5I3MA 1B8YA 2J0TA 1YCMA 1BQQM 5CZMA 2X3AA 3ZVSA 3EHYA 1IABA 1OS2A 4H76A 1RM8A 1KBCA 3WV2A 4PKUA 1XFWA 3E8RA 4XM6A 1BKCE 2JT6A 1ZXVA 3F17A 4WKEA 3KEJA 3K7NA 1JAQA 3LJTA 3I7IA 1A86A 4PKSA 4DF9A 3SHIA 1MMBA 3LK8A 830CA 2Y6DA 4DD8A 4G9LA 4H2EA 2USNA 1FLSA 2RJPA 3O64A 2CLTA 3DPEA 1JIWP 3BA0A 5D1UA 1HY7A 2X3BA 1ROSA 1YQYA 2XS4A 1G4KA 2V4BA 3LUMA 2J83A 4WZVA 1OM7A 2OI0A 1JKYA 1UEAA 2FV9A 1G49A 4L6TA 1D8FA 1ASTA 2ERQA 1OS9A 3NX7A 1IACA 1MMQA 1XUCA 3HDAP 3DSLA 1XUDA 4GR0A 2O36A 1PWVA 4XCTA 1MNCA 5I0LA 1WNIA 5JMYA 3K7LA 5D3CA 3I7GA 4DV8A 1GE5A 3LILA 4HX3A 4JIJA 4G0DA 1K7QA 2K9CA 2L0RA 5BOYA 2POJA 5B5PA 2W15A 5I2ZA 5B5OA 2MLSA 3DL1A 2DDFA 3LIKA 1I73A 2MZEA 3G42A 2WO9A 1R1JA 4IJOA 4PKQA 1CAQA 4XM7A 1QIAA 3LGPA 1SU3A 1S4BP 3HYGA 1HFSA 1J7NA 1HTDA 2JSDA 1G12A 1H71P 2QPJA 3L0TA 4L19A 5L79A 5CXAA 2DDYA 1UMSA 4AXQA 3LKAA 1CGEA 2OW9A 2HU6A 4DPEA 2OW2A 1AYKA 1JK3A 3KECA 1KUHA 2MZHA 4PKRA 1XFVA 3U1RA 3F15A 2D1NA 2JT5A 1A85A 2JNPA 4AUOA 1AKLA 2OXUA 1BM6A 4GQLA 1C7KA 1FBLA 1Y8JA 1I1IP 2DW2A 1SMPA 3B92A 1OMJA 1B3DA 2K2GA 4JP4A 3Q2HA 2W14A 1DTHA 3KEKA 4ON1A 5H8XA 4H49A 2OXWA 1CXVA 4GR8A 3MA2A 3EDHA 3P1VA 2DW0A 1XFYA 3P24A 1I76A 1GXDA 3G5CA 1BQOA 2AYKA 3USNA 3KHIA 1D5JA 1EAKA 2AIGP 4H3XA 3LE9A 3LJZA 1MMRA 2OY4A 4Q1LA 1XURA 1JJ9A 3EHXA 1ND1A 1QICA 2OY2A 2Y6CA 3V96B 3VTGA 5D2BA 3EDGA 4WF6A 2MZIA 4XM8A 1C3IA 4GWNA 4IUWA 1ZP5A 3HY7A 3TT4A 4QKZA 1CGLA 2N8RA 5BOTA 4FXYP 3TVCA 3N2UA 2E2DA 1KUIA 1QUAA 1ZXCA 4WKIA 3DNGA 1XFUA 1R55A 2PJTA 1BZSA 1BUVM 2OW1A 3AIGA 3HY9A 3LQBA 2FV5A 1HOVA 3EDIA 1AF0A 4ZR5A 1SRPA 2CKIA 3DWBA 1OM6A 3KMEA 4GUYA 4JPAA 1UMTA 1HV5A 3KRYA 4AIGA 1PWQA 1GO8P 2YIGA 4GF1A 1GKCA 4HMAA 2I47A 1GKDA 1EB6A 4IN9A 1KAPP 1CQRA 3F1AA 4I03A 1GE7A 1YP1A 3AYKA 1IAGA 2E3XA 2TCLA 5D1TA 3TSKA 1BIWA 2OZRA 1CK7A 1O0TA 3F16A 1BUDA 966CA 2W0DA 4A3WA 456CA 3LQ0A 1ZVXA 1CIZA 5I4OA 1JIZA 1C8TA 2OXZA 3ZUKA 1K7GA 2W12A 3F19A 1IAEA 1R1HA 2MLRA 2JIHA 1OO9A 1KUGA 2Z2DA 1DMTA 1KUKA 4EFSA 1MMPA 4R3VA 3KWVC 3B2ZA 2O3EA 5BPAA 1EUBA 5D1SA 3LIRA 4FVLA 1HFCA 1BKCI 3VI1A 1D8MA 1JAPA 2A8HA 1QJIA 5L7FA 1G05A 3ELMA 2YB9A 3HBUP 2ERPA 3AYUA 1L6JA 4H30A 1RMZA 1O0QA 1Q3AA 1JAOA 5D7WA 2XS3A 4H84A 3WV1A 4WK7A 3ZXHA 4JQGA 1YOUA 4CTHA 1UTTA 4H82A 1IAAA 1SLNA 3HBVP 4ILWD 3CKIA 4GWMA 4AYKA 1IADA 1R1IA 1ATLA 5CUHA 4PKVA 3O2XA 4L63A 2RJQA 4FU4A 1XFZA 3GBOA 1G9KA 1OM8A 3HB2P 1JH1A 2DW1A 2WO8A 1FM1A 3OHLA
chains in the Genus database with same CATH superfamily
1ZS0A 4XBHA 5I43A 3DTKA 4GR3A 3EDZA 1KUFA 1XFXA 1SLMA 1Y93A 2SRTA 2X3CA 3WV3A 1PWPA 1GE6A 2OVZA 1CGFA 1UTZA 3RTTA 4JA1A 1BSWA 2OVXA 2W13A 1JANA 2WOAA 3L0VA 2OW0A 3B8ZA 1ZTQA 1BKCA 5I12A 4H1QA 4PKTA 2D1OA 1Y0VA 1QIBA 1R54A 4J4MA 3N2VA 1PWUA 3LUNA 3TS4A 3LJGA 4I35A 5LABA 4PKWA 1SATA 3OHOA 1GO7P 3KMCA 3LEAA 3RTSA 3LMCA 4A7BA 3DPFA 3F18A 1D7XA 3Q2GA 2EROA 1Z3JA 2X7MA 3HDBA 1PWWA 4FXQA 3EWJA 1QJJA 2KRJA 3UVCA 1K7IA 1USNA 5I3MA 1B8YA 2J0TA 1YCMA 1BQQM 5CZMA 2X3AA 3ZVSA 3EHYA 1IABA 1OS2A 4H76A 1RM8A 1KBCA 3WV2A 4PKUA 3DTIA 1XFWA 3E8RA 4XM6A 1BKCE 2JT6A 1ZXVA 3F17A 4WKEA 3KEJA 3K7NA 1JAQA 3LJTA 3I7IA 1A86A 4PKSA 4DF9A 3SHIA 1XM5A 1MMBA 3LK8A 830CA 2Y6DA 4DD8A 4G9LA 4H2EA 2USNA 1FLSA 2RJPA 3O64A 2CLTA 3DPEA 1JIWP 3BA0A 5D1UA 1HY7A 2X3BA 1ROSA 1YQYA 2XS4A 1G4KA 2V4BA 3LUMA 2J83A 4WZVA 1OM7A 2OI0A 1JKYA 1UEAA 2FV9A 1G49A 4L6TA 1D8FA 1ASTA 2ERQA 1OS9A 3NX7A 1IACA 1MMQA 1XUCA 3HDAP 3DSLA 1XUDA 4GR0A 2O36A 1PWVA 4XCTA 1MNCA 5I0LA 1WNIA 5JMYA 3K7LA 5D3CA 3I7GA 4DV8A 1GE5A 3LILA 4HX3A 4JIJA 4G0DA 1K7QA 2K9CA 2L0RA 5BOYA 2POJA 5B5PA 2W15A 5I2ZA 5B5OA 2MLSA 3DL1A 2DDFA 3LIKA 1I73A 2MZEA 3G42A 2WO9A 1R1JA 4IJOA 4PKQA 1CAQA 4XM7A 1QIAA 3LGPA 1SU3A 1S4BP 3HYGA 1HFSA 1J7NA 1HTDA 2JSDA 1G12A 1OZ9A 1H71P 2QPJA 3L0TA 4L19A 5L79A 5CXAA 2DDYA 1UMSA 4AXQA 3LKAA 1CGEA 2OW9A 2HU6A 4DPEA 2OW2A 1AYKA 1JK3A 3KECA 3DTEA 1KUHA 2MZHA 4PKRA 1XFVA 3U1RA 3F15A 2D1NA 2JT5A 1A85A 2JNPA 4AUOA 1AKLA 2OXUA 1BM6A 4GQLA 1C7KA 1FBLA 1Y8JA 1I1IP 2DW2A 1SMPA 3B92A 1OMJA 1B3DA 2K2GA 4JP4A 3Q2HA 2W14A 1DTHA 3KEKA 4ON1A 5H8XA 4H49A 2OXWA 1CXVA 4GR8A 3MA2A 3EDHA 3P1VA 1XAXA 2DW0A 1XFYA 3P24A 1I76A 1GXDA 3G5CA 1BQOA 2AYKA 3USNA 3KHIA 1D5JA 1EAKA 2AIGP 4H3XA 3LE9A 3LJZA 1MMRA 2OY4A 4Q1LA 1XURA 1JJ9A 3EHXA 1ND1A 1QICA 2OY2A 2Y6CA 3V96B 3VTGA 5D2BA 1TVIA 3EDGA 4WF6A 2MZIA 4XM8A 1C3IA 4GWNA 2YUFA 4IUWA 1ZP5A 3HY7A 3TT4A 4QKZA 1CGLA 2N8RA 5BOTA 4FXYP 3TVCA 3N2UA 2E2DA 1KUIA 1QUAA 1ZXCA 4WKIA 3DNGA 1XFUA 1R55A 2PJTA 1BZSA 1BUVM 2OW1A 3AIGA 3HY9A 3LQBA 2FV5A 1HOVA 3EDIA 1AF0A 4ZR5A 1SRPA 2CKIA 3DWBA 1OM6A 3KMEA 4GUYA 4JPAA 1UMTA 1HV5A 3KRYA 4AIGA 1PWQA 1GO8P 2YIGA 4GF1A 1GKCA 4HMAA 2I47A 1GKDA 1EB6A 4IN9A 1KAPP 1CQRA 3F1AA 4I03A 1GE7A 1YP1A 3AYKA 1IAGA 2E3XA 2TCLA 5D1TA 3TSKA 1BIWA 2OZRA 1CK7A 1O0TA 3F16A 1BUDA 966CA 2W0DA 4A3WA 4L7AA 456CA 3LQ0A 1ZVXA 1CIZA 5I4OA 1JIZA 1C8TA 2OXZA 3ZUKA 1K7GA 2W12A 3F19A 1IAEA 1R1HA 2MLRA 2JIHA 1OO9A 1KUGA 2Z2DA 1DMTA 1KUKA 4EFSA 1MMPA 4R3VA 3KWVC 3B2ZA 2O3EA 5BPAA 1EUBA 5D1SA 3LIRA 4FVLA 1HFCA 1BKCI 3VI1A 1D8MA 1JAPA 2A8HA 1QJIA 5L7FA 1G05A 3ELMA 2YB9A 3HBUP 2ERPA 3AYUA 1L6JA 4H30A 1RMZA 1O0QA 1Q3AA 1JAOA 5D7WA 2XS3A 4H84A 3WV1A 4WK7A 3ZXHA 4JQGA 1YOUA 4CTHA 1UTTA 4H82A 1IAAA 1SLNA 3HBVP 4ILWD 3CKIA 4GWMA 4AYKA 1IADA 1R1IA 1ATLA 5CUHA 4PKVA 3O2XA 4L63A 2RJQA 4FU4A 1XFZA 3GBOA 1G9KA 1OM8A 3HB2P 1JH1A 2DW1A 2WO8A 1FM1A 3OHLA
chains in the Genus database with same CATH topology
1ZS0A 4XBHA 5I43A 3DTKA 4GR3A 3EDZA 1KUFA 1XFXA 1SLMA 1Y93A 2SRTA 2X3CA 3WV3A 1PWPA 1GE6A 2OVZA 1CGFA 1UTZA 3RTTA 4JA1A 1BSWA 2OVXA 2W13A 1JANA 2WOAA 3L0VA 2OW0A 3B8ZA 1ZTQA 1BKCA 5I12A 4H1QA 4PKTA 2D1OA 1Y0VA 1QIBA 1R54A 4J4MA 3N2VA 1PWUA 3LUNA 3TS4A 3LJGA 4I35A 5LABA 4PKWA 1SATA 3OHOA 1GO7P 3KMCA 3LEAA 3RTSA 3LMCA 4A7BA 3DPFA 3F18A 1D7XA 3Q2GA 2EROA 1Z3JA 2X7MA 3HDBA 1PWWA 4FXQA 3EWJA 1QJJA 2KRJA 3UVCA 1K7IA 1USNA 5I3MA 1B8YA 2J0TA 1YCMA 1BQQM 5CZMA 2X3AA 3ZVSA 3EHYA 1IABA 1OS2A 4H76A 1RM8A 1KBCA 3WV2A 4PKUA 3DTIA 1XFWA 3E8RA 4XM6A 1BKCE 2JT6A 1ZXVA 3F17A 4WKEA 3KEJA 3K7NA 1JAQA 3LJTA 3I7IA 1A86A 4PKSA 4DF9A 3SHIA 1MMBA 3LK8A 830CA 2Y6DA 4DD8A 4G9LA 4H2EA 2USNA 1FLSA 2RJPA 3O64A 2CLTA 3DPEA 1JIWP 3BA0A 5D1UA 1HY7A 2X3BA 1ROSA 1YQYA 2XS4A 1G4KA 2V4BA 3LUMA 2J83A 4WZVA 1OM7A 2OI0A 1JKYA 1UEAA 2FV9A 1G49A 4L6TA 1D8FA 1ASTA 2ERQA 1OS9A 3NX7A 1IACA 1MMQA 1XUCA 3HDAP 3DSLA 1XUDA 4GR0A 2O36A 1PWVA 4XCTA 1MNCA 5I0LA 1WNIA 5JMYA 3K7LA 5D3CA 3I7GA 4DV8A 1GE5A 3LILA 4HX3A 4JIJA 4G0DA 1K7QA 2K9CA 2L0RA 5BOYA 2POJA 5B5PA 2W15A 5I2ZA 5B5OA 2MLSA 3DL1A 2DDFA 3LIKA 1I73A 2MZEA 3G42A 2WO9A 1R1JA 4IJOA 4PKQA 1CAQA 4XM7A 1QIAA 3LGPA 1SU3A 1S4BP 3HYGA 1HFSA 1J7NA 1HTDA 2JSDA 1G12A 1H71P 2QPJA 3L0TA 4L19A 5L79A 5CXAA 2DDYA 1UMSA 4AXQA 3LKAA 1CGEA 2OW9A 2HU6A 4DPEA 2OW2A 1AYKA 1JK3A 3KECA 3DTEA 1KUHA 2MZHA 4PKRA 1XFVA 3U1RA 3F15A 2D1NA 2JT5A 1A85A 2JNPA 4AUOA 1AKLA 2OXUA 1BM6A 4GQLA 1C7KA 1FBLA 1Y8JA 1I1IP 2DW2A 1SMPA 3B92A 1OMJA 1B3DA 2K2GA 4JP4A 3Q2HA 2W14A 1DTHA 3KEKA 4ON1A 5H8XA 4H49A 2OXWA 1CXVA 4GR8A 3MA2A 3EDHA 3P1VA 2DW0A 1XFYA 3P24A 1I76A 1GXDA 3G5CA 1BQOA 2AYKA 3USNA 3KHIA 1D5JA 1EAKA 2AIGP 4H3XA 3LE9A 3LJZA 1MMRA 2OY4A 4Q1LA 1XURA 1JJ9A 3EHXA 1ND1A 1QICA 2OY2A 2Y6CA 3V96B 3VTGA 5D2BA 3EDGA 4WF6A 2MZIA 4XM8A 1C3IA 4GWNA 2YUFA 4IUWA 1ZP5A 3HY7A 3TT4A 4QKZA 1CGLA 2N8RA 5BOTA 4FXYP 3TVCA 3N2UA 2E2DA 1KUIA 1QUAA 1ZXCA 4WKIA 3DNGA 1XFUA 1R55A 2PJTA 1BZSA 1BUVM 2OW1A 3AIGA 3HY9A 3LQBA 2FV5A 1HOVA 3EDIA 1AF0A 4ZR5A 1SRPA 2CKIA 3DWBA 1OM6A 3KMEA 4GUYA 4JPAA 1UMTA 1HV5A 3KRYA 4AIGA 1PWQA 1GO8P 2YIGA 4GF1A 1GKCA 4HMAA 2I47A 1GKDA 1EB6A 4IN9A 1KAPP 1CQRA 3F1AA 4I03A 1GE7A 1YP1A 3AYKA 1IAGA 2E3XA 2TCLA 5D1TA 3TSKA 1BIWA 2OZRA 1CK7A 1O0TA 3F16A 1BUDA 966CA 2W0DA 4A3WA 4L7AA 456CA 3LQ0A 1ZVXA 1CIZA 5I4OA 1JIZA 1C8TA 2OXZA 3ZUKA 1K7GA 2W12A 3F19A 1IAEA 1R1HA 2MLRA 2JIHA 1OO9A 1KUGA 2Z2DA 1DMTA 1KUKA 4EFSA 1MMPA 4R3VA 3KWVC 3B2ZA 2O3EA 5BPAA 1EUBA 5D1SA 3LIRA 4FVLA 1HFCA 1BKCI 3VI1A 1D8MA 1JAPA 2A8HA 1QJIA 5L7FA 1G05A 3ELMA 2YB9A 3HBUP 2ERPA 3AYUA 1L6JA 4H30A 1RMZA 1O0QA 1Q3AA 1JAOA 5D7WA 2XS3A 4H84A 3WV1A 4WK7A 3ZXHA 4JQGA 1YOUA 4CTHA 1UTTA 4H82A 1IAAA 1SLNA 3HBVP 4ILWD 3CKIA 4GWMA 4AYKA 1IADA 1R1IA 1ATLA 5CUHA 4PKVA 3O2XA 4L63A 2RJQA 4FU4A 1XFZA 3GBOA 1G9KA 1OM8A 3HB2P 1JH1A 2DW1A 2WO8A 1FM1A 3OHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZS0 A;  4XBH A;  5I43 A;  4GR3 A;  3EDZ A;  1KUF A;  1XFX A;  1SLM A;  1Y93 A;  2SRT A;  2X3C A;  3WV3 A;  1PWP A;  1GE6 A;  2OVZ A;  1CGF A;  1UTZ A;  3RTT A;  4JA1 A;  1BSW A;  2OVX A;  2W13 A;  1JAN A;  2WOA A;  3L0V A;  2OW0 A;  3B8Z A;  1ZTQ A;  1BKC A;  5I12 A;  4H1Q A;  4PKT A;  2D1O A;  1Y0V A;  1QIB A;  1R54 A;  4J4M A;  3N2V A;  1PWU A;  3LUN A;  3TS4 A;  3LJG A;  4I35 A;  5LAB A;  4PKW A;  1SAT A;  3OHO A;  1GO7 P;  3KMC A;  3LEA A;  3RTS A;  3LMC A;  4A7B A;  3DPF A;  3F18 A;  1D7X A;  3Q2G A;  2ERO A;  1Z3J A;  2X7M A;  3HDB A;  1PWW A;  4FXQ A;  3EWJ A;  1QJJ A;  2KRJ A;  3UVC A;  1K7I A;  1USN A;  5I3M A;  1B8Y A;  2J0T A;  1YCM A;  1BQQ M;  5CZM A;  2X3A A;  3ZVS A;  3EHY A;  1IAB A;  1OS2 A;  4H76 A;  1RM8 A;  1KBC A;  3WV2 A;  4PKU A;  1XFW A;  3E8R A;  4XM6 A;  1BKC E;  2JT6 A;  1ZXV A;  3F17 A;  4WKE A;  3KEJ A;  3K7N A;  1JAQ A;  3LJT A;  3I7I A;  1A86 A;  4PKS A;  4DF9 A;  3SHI A;  1MMB A;  3LK8 A;  830C A;  2Y6D A;  4DD8 A;  4G9L A;  4H2E A;  2USN A;  1FLS A;  2RJP A;  3O64 A;  2CLT A;  3DPE A;  1JIW P;  3BA0 A;  5D1U A;  1HY7 A;  2X3B A;  1ROS A;  1YQY A;  2XS4 A;  1G4K A;  2V4B A;  3LUM A;  2J83 A;  4WZV A;  1OM7 A;  2OI0 A;  1JKY A;  1UEA A;  2FV9 A;  1G49 A;  4L6T A;  1D8F A;  1AST A;  2ERQ A;  1OS9 A;  3NX7 A;  1IAC A;  1MMQ A;  1XUC A;  3HDA P;  3DSL A;  1XUD A;  4GR0 A;  2O36 A;  1PWV A;  4XCT A;  1MNC A;  5I0L A;  1WNI A;  5JMY A;  3K7L A;  5D3C A;  3I7G A;  4DV8 A;  1GE5 A;  3LIL A;  4HX3 A;  4JIJ A;  4G0D A;  1K7Q A;  2K9C A;  2L0R A;  5BOY A;  2POJ A;  5B5P A;  2W15 A;  5I2Z A;  5B5O A;  2MLS A;  3DL1 A;  2DDF A;  3LIK A;  1I73 A;  2MZE A;  3G42 A;  2WO9 A;  1R1J A;  4IJO A;  4PKQ A;  1CAQ A;  4XM7 A;  1QIA A;  3LGP A;  1SU3 A;  1S4B P;  3HYG A;  1HFS A;  1J7N A;  1HTD A;  2JSD A;  1G12 A;  1H71 P;  2QPJ A;  3L0T A;  4L19 A;  5L79 A;  5CXA A;  2DDY A;  1UMS A;  4AXQ A;  3LKA A;  1CGE A;  2OW9 A;  2HU6 A;  4DPE A;  2OW2 A;  1AYK A;  1JK3 A;  3KEC A;  1KUH A;  2MZH A;  4PKR A;  1XFV A;  3U1R A;  3F15 A;  2D1N A;  2JT5 A;  1A85 A;  2JNP A;  4AUO A;  1AKL A;  2OXU A;  1BM6 A;  4GQL A;  1C7K A;  1FBL A;  1Y8J A;  1I1I P;  2DW2 A;  1SMP A;  3B92 A;  1OMJ A;  1B3D A;  2K2G A;  4JP4 A;  3Q2H A;  2W14 A;  1DTH A;  3KEK A;  4ON1 A;  5H8X A;  4H49 A;  2OXW A;  1CXV A;  4GR8 A;  3MA2 A;  3EDH A;  3P1V A;  2DW0 A;  1XFY A;  3P24 A;  1I76 A;  1GXD A;  3G5C A;  1BQO A;  2AYK A;  3USN A;  3KHI A;  1D5J A;  1EAK A;  2AIG P;  4H3X A;  3LE9 A;  3LJZ A;  1MMR A;  2OY4 A;  4Q1L A;  1XUR A;  1JJ9 A;  3EHX A;  1ND1 A;  1QIC A;  2OY2 A;  2Y6C A;  3V96 B;  3VTG A;  5D2B A;  3EDG A;  4WF6 A;  2MZI A;  4XM8 A;  1C3I A;  4GWN A;  4IUW A;  1ZP5 A;  3HY7 A;  3TT4 A;  4QKZ A;  1CGL A;  2N8R A;  5BOT A;  4FXY P;  3TVC A;  3N2U A;  2E2D A;  1KUI A;  1QUA A;  1ZXC A;  4WKI A;  3DNG A;  1XFU A;  1R55 A;  2PJT A;  1BZS A;  1BUV M;  2OW1 A;  3AIG A;  3HY9 A;  3LQB A;  2FV5 A;  1HOV A;  3EDI A;  1AF0 A;  4ZR5 A;  1SRP A;  2CKI A;  3DWB A;  1OM6 A;  3KME A;  4GUY A;  4JPA A;  1UMT A;  1HV5 A;  3KRY A;  4AIG A;  1PWQ A;  1GO8 P;  2YIG A;  4GF1 A;  1GKC A;  4HMA A;  2I47 A;  1GKD A;  1EB6 A;  4IN9 A;  1KAP P;  1CQR A;  3F1A A;  4I03 A;  1GE7 A;  1YP1 A;  3AYK A;  1IAG A;  2E3X A;  2TCL A;  5D1T A;  3TSK A;  1BIW A;  2OZR A;  1CK7 A;  1O0T A;  3F16 A;  1BUD A;  966C A;  2W0D A;  4A3W A;  456C A;  3LQ0 A;  1ZVX A;  1CIZ A;  5I4O A;  1JIZ A;  1C8T A;  2OXZ A;  3ZUK A;  1K7G A;  2W12 A;  3F19 A;  1IAE A;  1R1H A;  2MLR A;  2JIH A;  1OO9 A;  1KUG A;  2Z2D A;  1DMT A;  1KUK A;  4EFS A;  1MMP A;  4R3V A;  3KWV C;  3B2Z A;  2O3E A;  5BPA A;  1EUB A;  5D1S A;  3LIR A;  4FVL A;  1HFC A;  1BKC I;  3VI1 A;  1D8M A;  1JAP A;  2A8H A;  1QJI A;  5L7F A;  1G05 A;  3ELM A;  2YB9 A;  3HBU P;  2ERP A;  3AYU A;  1L6J A;  4H30 A;  1RMZ A;  1O0Q A;  1Q3A A;  1JAO A;  5D7W A;  2XS3 A;  4H84 A;  3WV1 A;  4WK7 A;  3ZXH A;  4JQG A;  1YOU A;  4CTH A;  1UTT A;  4H82 A;  1IAA A;  1SLN A;  3HBV P;  4ILW D;  3CKI A;  4GWM A;  4AYK A;  1IAD A;  1R1I A;  1ATL A;  5CUH A;  4PKV A;  3O2X A;  4L63 A;  2RJQ A;  4FU4 A;  1XFZ A;  3GBO A;  1G9K A;  1OM8 A;  3HB2 P;  1JH1 A;  2DW1 A;  2WO8 A;  1FM1 A;  3OHL A; 
#chains in the Genus database with same CATH topology
 1ZS0 A;  4XBH A;  5I43 A;  3DTK A;  4GR3 A;  3EDZ A;  1KUF A;  1XFX A;  1SLM A;  1Y93 A;  2SRT A;  2X3C A;  3WV3 A;  1PWP A;  1GE6 A;  2OVZ A;  1CGF A;  1UTZ A;  3RTT A;  4JA1 A;  1BSW A;  2OVX A;  2W13 A;  1JAN A;  2WOA A;  3L0V A;  2OW0 A;  3B8Z A;  1ZTQ A;  1BKC A;  5I12 A;  4H1Q A;  4PKT A;  2D1O A;  1Y0V A;  1QIB A;  1R54 A;  4J4M A;  3N2V A;  1PWU A;  3LUN A;  3TS4 A;  3LJG A;  4I35 A;  5LAB A;  4PKW A;  1SAT A;  3OHO A;  1GO7 P;  3KMC A;  3LEA A;  3RTS A;  3LMC A;  4A7B A;  3DPF A;  3F18 A;  1D7X A;  3Q2G A;  2ERO A;  1Z3J A;  2X7M A;  3HDB A;  1PWW A;  4FXQ A;  3EWJ A;  1QJJ A;  2KRJ A;  3UVC A;  1K7I A;  1USN A;  5I3M A;  1B8Y A;  2J0T A;  1YCM A;  1BQQ M;  5CZM A;  2X3A A;  3ZVS A;  3EHY A;  1IAB A;  1OS2 A;  4H76 A;  1RM8 A;  1KBC A;  3WV2 A;  4PKU A;  3DTI A;  1XFW A;  3E8R A;  4XM6 A;  1BKC E;  2JT6 A;  1ZXV A;  3F17 A;  4WKE A;  3KEJ A;  3K7N A;  1JAQ A;  3LJT A;  3I7I A;  1A86 A;  4PKS A;  4DF9 A;  3SHI A;  1XM5 A;  1MMB A;  3LK8 A;  830C A;  2Y6D A;  4DD8 A;  4G9L A;  4H2E A;  2USN A;  1FLS A;  2RJP A;  3O64 A;  2CLT A;  3DPE A;  1JIW P;  3BA0 A;  5D1U A;  1HY7 A;  2X3B A;  1ROS A;  1YQY A;  2XS4 A;  1G4K A;  2V4B A;  3LUM A;  2J83 A;  4WZV A;  1OM7 A;  2OI0 A;  1JKY A;  1UEA A;  2FV9 A;  1G49 A;  4L6T A;  1D8F A;  1AST A;  2ERQ A;  1OS9 A;  3NX7 A;  1IAC A;  1MMQ A;  1XUC A;  3HDA P;  3DSL A;  1XUD A;  4GR0 A;  2O36 A;  1PWV A;  4XCT A;  1MNC A;  5I0L A;  1WNI A;  5JMY A;  3K7L A;  5D3C A;  3I7G A;  4DV8 A;  1GE5 A;  3LIL A;  4HX3 A;  4JIJ A;  4G0D A;  1K7Q A;  2K9C A;  2L0R A;  5BOY A;  2POJ A;  5B5P A;  2W15 A;  5I2Z A;  5B5O A;  2MLS A;  3DL1 A;  2DDF A;  3LIK A;  1I73 A;  2MZE A;  3G42 A;  2WO9 A;  1R1J A;  4IJO A;  4PKQ A;  1CAQ A;  4XM7 A;  1QIA A;  3LGP A;  1SU3 A;  1S4B P;  3HYG A;  1HFS A;  1J7N A;  1HTD A;  2JSD A;  1G12 A;  1OZ9 A;  1H71 P;  2QPJ A;  3L0T A;  4L19 A;  5L79 A;  5CXA A;  2DDY A;  1UMS A;  4AXQ A;  3LKA A;  1CGE A;  2OW9 A;  2HU6 A;  4DPE A;  2OW2 A;  1AYK A;  1JK3 A;  3KEC A;  3DTE A;  1KUH A;  2MZH A;  4PKR A;  1XFV A;  3U1R A;  3F15 A;  2D1N A;  2JT5 A;  1A85 A;  2JNP A;  4AUO A;  1AKL A;  2OXU A;  1BM6 A;  4GQL A;  1C7K A;  1FBL A;  1Y8J A;  1I1I P;  2DW2 A;  1SMP A;  3B92 A;  1OMJ A;  1B3D A;  2K2G A;  4JP4 A;  3Q2H A;  2W14 A;  1DTH A;  3KEK A;  4ON1 A;  5H8X A;  4H49 A;  2OXW A;  1CXV A;  4GR8 A;  3MA2 A;  3EDH A;  3P1V A;  1XAX A;  2DW0 A;  1XFY A;  3P24 A;  1I76 A;  1GXD A;  3G5C A;  1BQO A;  2AYK A;  3USN A;  3KHI A;  1D5J A;  1EAK A;  2AIG P;  4H3X A;  3LE9 A;  3LJZ A;  1MMR A;  2OY4 A;  4Q1L A;  1XUR A;  1JJ9 A;  3EHX A;  1ND1 A;  1QIC A;  2OY2 A;  2Y6C A;  3V96 B;  3VTG A;  5D2B A;  1TVI A;  3EDG A;  4WF6 A;  2MZI A;  4XM8 A;  1C3I A;  4GWN A;  2YUF A;  4IUW A;  1ZP5 A;  3HY7 A;  3TT4 A;  4QKZ A;  1CGL A;  2N8R A;  5BOT A;  4FXY P;  3TVC A;  3N2U A;  2E2D A;  1KUI A;  1QUA A;  1ZXC A;  4WKI A;  3DNG A;  1XFU A;  1R55 A;  2PJT A;  1BZS A;  1BUV M;  2OW1 A;  3AIG A;  3HY9 A;  3LQB A;  2FV5 A;  1HOV A;  3EDI A;  1AF0 A;  4ZR5 A;  1SRP A;  2CKI A;  3DWB A;  1OM6 A;  3KME A;  4GUY A;  4JPA A;  1UMT A;  1HV5 A;  3KRY A;  4AIG A;  1PWQ A;  1GO8 P;  2YIG A;  4GF1 A;  1GKC A;  4HMA A;  2I47 A;  1GKD A;  1EB6 A;  4IN9 A;  1KAP P;  1CQR A;  3F1A A;  4I03 A;  1GE7 A;  1YP1 A;  3AYK A;  1IAG A;  2E3X A;  2TCL A;  5D1T A;  3TSK A;  1BIW A;  2OZR A;  1CK7 A;  1O0T A;  3F16 A;  1BUD A;  966C A;  2W0D A;  4A3W A;  4L7A A;  456C A;  3LQ0 A;  1ZVX A;  1CIZ A;  5I4O A;  1JIZ A;  1C8T A;  2OXZ A;  3ZUK A;  1K7G A;  2W12 A;  3F19 A;  1IAE A;  1R1H A;  2MLR A;  2JIH A;  1OO9 A;  1KUG A;  2Z2D A;  1DMT A;  1KUK A;  4EFS A;  1MMP A;  4R3V A;  3KWV C;  3B2Z A;  2O3E A;  5BPA A;  1EUB A;  5D1S A;  3LIR A;  4FVL A;  1HFC A;  1BKC I;  3VI1 A;  1D8M A;  1JAP A;  2A8H A;  1QJI A;  5L7F A;  1G05 A;  3ELM A;  2YB9 A;  3HBU P;  2ERP A;  3AYU A;  1L6J A;  4H30 A;  1RMZ A;  1O0Q A;  1Q3A A;  1JAO A;  5D7W A;  2XS3 A;  4H84 A;  3WV1 A;  4WK7 A;  3ZXH A;  4JQG A;  1YOU A;  4CTH A;  1UTT A;  4H82 A;  1IAA A;  1SLN A;  3HBV P;  4ILW D;  3CKI A;  4GWM A;  4AYK A;  1IAD A;  1R1I A;  1ATL A;  5CUH A;  4PKV A;  3O2X A;  4L63 A;  2RJQ A;  4FU4 A;  1XFZ A;  3GBO A;  1G9K A;  1OM8 A;  3HB2 P;  1JH1 A;  2DW1 A;  2WO8 A;  1FM1 A;  3OHL A; 
#chains in the Genus database with same CATH homology
 1ZS0 A;  4XBH A;  5I43 A;  3DTK A;  4GR3 A;  3EDZ A;  1KUF A;  1XFX A;  1SLM A;  1Y93 A;  2SRT A;  2X3C A;  3WV3 A;  1PWP A;  1GE6 A;  2OVZ A;  1CGF A;  1UTZ A;  3RTT A;  4JA1 A;  1BSW A;  2OVX A;  2W13 A;  1JAN A;  2WOA A;  3L0V A;  2OW0 A;  3B8Z A;  1ZTQ A;  1BKC A;  5I12 A;  4H1Q A;  4PKT A;  2D1O A;  1Y0V A;  1QIB A;  1R54 A;  4J4M A;  3N2V A;  1PWU A;  3LUN A;  3TS4 A;  3LJG A;  4I35 A;  5LAB A;  4PKW A;  1SAT A;  3OHO A;  1GO7 P;  3KMC A;  3LEA A;  3RTS A;  3LMC A;  4A7B A;  3DPF A;  3F18 A;  1D7X A;  3Q2G A;  2ERO A;  1Z3J A;  2X7M A;  3HDB A;  1PWW A;  4FXQ A;  3EWJ A;  1QJJ A;  2KRJ A;  3UVC A;  1K7I A;  1USN A;  5I3M A;  1B8Y A;  2J0T A;  1YCM A;  1BQQ M;  5CZM A;  2X3A A;  3ZVS A;  3EHY A;  1IAB A;  1OS2 A;  4H76 A;  1RM8 A;  1KBC A;  3WV2 A;  4PKU A;  3DTI A;  1XFW A;  3E8R A;  4XM6 A;  1BKC E;  2JT6 A;  1ZXV A;  3F17 A;  4WKE A;  3KEJ A;  3K7N A;  1JAQ A;  3LJT A;  3I7I A;  1A86 A;  4PKS A;  4DF9 A;  3SHI A;  1MMB A;  3LK8 A;  830C A;  2Y6D A;  4DD8 A;  4G9L A;  4H2E A;  2USN A;  1FLS A;  2RJP A;  3O64 A;  2CLT A;  3DPE A;  1JIW P;  3BA0 A;  5D1U A;  1HY7 A;  2X3B A;  1ROS A;  1YQY A;  2XS4 A;  1G4K A;  2V4B A;  3LUM A;  2J83 A;  4WZV A;  1OM7 A;  2OI0 A;  1JKY A;  1UEA A;  2FV9 A;  1G49 A;  4L6T A;  1D8F A;  1AST A;  2ERQ A;  1OS9 A;  3NX7 A;  1IAC A;  1MMQ A;  1XUC A;  3HDA P;  3DSL A;  1XUD A;  4GR0 A;  2O36 A;  1PWV A;  4XCT A;  1MNC A;  5I0L A;  1WNI A;  5JMY A;  3K7L A;  5D3C A;  3I7G A;  4DV8 A;  1GE5 A;  3LIL A;  4HX3 A;  4JIJ A;  4G0D A;  1K7Q A;  2K9C A;  2L0R A;  5BOY A;  2POJ A;  5B5P A;  2W15 A;  5I2Z A;  5B5O A;  2MLS A;  3DL1 A;  2DDF A;  3LIK A;  1I73 A;  2MZE A;  3G42 A;  2WO9 A;  1R1J A;  4IJO A;  4PKQ A;  1CAQ A;  4XM7 A;  1QIA A;  3LGP A;  1SU3 A;  1S4B P;  3HYG A;  1HFS A;  1J7N A;  1HTD A;  2JSD A;  1G12 A;  1H71 P;  2QPJ A;  3L0T A;  4L19 A;  5L79 A;  5CXA A;  2DDY A;  1UMS A;  4AXQ A;  3LKA A;  1CGE A;  2OW9 A;  2HU6 A;  4DPE A;  2OW2 A;  1AYK A;  1JK3 A;  3KEC A;  3DTE A;  1KUH A;  2MZH A;  4PKR A;  1XFV A;  3U1R A;  3F15 A;  2D1N A;  2JT5 A;  1A85 A;  2JNP A;  4AUO A;  1AKL A;  2OXU A;  1BM6 A;  4GQL A;  1C7K A;  1FBL A;  1Y8J A;  1I1I P;  2DW2 A;  1SMP A;  3B92 A;  1OMJ A;  1B3D A;  2K2G A;  4JP4 A;  3Q2H A;  2W14 A;  1DTH A;  3KEK A;  4ON1 A;  5H8X A;  4H49 A;  2OXW A;  1CXV A;  4GR8 A;  3MA2 A;  3EDH A;  3P1V A;  2DW0 A;  1XFY A;  3P24 A;  1I76 A;  1GXD A;  3G5C A;  1BQO A;  2AYK A;  3USN A;  3KHI A;  1D5J A;  1EAK A;  2AIG P;  4H3X A;  3LE9 A;  3LJZ A;  1MMR A;  2OY4 A;  4Q1L A;  1XUR A;  1JJ9 A;  3EHX A;  1ND1 A;  1QIC A;  2OY2 A;  2Y6C A;  3V96 B;  3VTG A;  5D2B A;  3EDG A;  4WF6 A;  2MZI A;  4XM8 A;  1C3I A;  4GWN A;  2YUF A;  4IUW A;  1ZP5 A;  3HY7 A;  3TT4 A;  4QKZ A;  1CGL A;  2N8R A;  5BOT A;  4FXY P;  3TVC A;  3N2U A;  2E2D A;  1KUI A;  1QUA A;  1ZXC A;  4WKI A;  3DNG A;  1XFU A;  1R55 A;  2PJT A;  1BZS A;  1BUV M;  2OW1 A;  3AIG A;  3HY9 A;  3LQB A;  2FV5 A;  1HOV A;  3EDI A;  1AF0 A;  4ZR5 A;  1SRP A;  2CKI A;  3DWB A;  1OM6 A;  3KME A;  4GUY A;  4JPA A;  1UMT A;  1HV5 A;  3KRY A;  4AIG A;  1PWQ A;  1GO8 P;  2YIG A;  4GF1 A;  1GKC A;  4HMA A;  2I47 A;  1GKD A;  1EB6 A;  4IN9 A;  1KAP P;  1CQR A;  3F1A A;  4I03 A;  1GE7 A;  1YP1 A;  3AYK A;  1IAG A;  2E3X A;  2TCL A;  5D1T A;  3TSK A;  1BIW A;  2OZR A;  1CK7 A;  1O0T A;  3F16 A;  1BUD A;  966C A;  2W0D A;  4A3W A;  4L7A A;  456C A;  3LQ0 A;  1ZVX A;  1CIZ A;  5I4O A;  1JIZ A;  1C8T A;  2OXZ A;  3ZUK A;  1K7G A;  2W12 A;  3F19 A;  1IAE A;  1R1H A;  2MLR A;  2JIH A;  1OO9 A;  1KUG A;  2Z2D A;  1DMT A;  1KUK A;  4EFS A;  1MMP A;  4R3V A;  3KWV C;  3B2Z A;  2O3E A;  5BPA A;  1EUB A;  5D1S A;  3LIR A;  4FVL A;  1HFC A;  1BKC I;  3VI1 A;  1D8M A;  1JAP A;  2A8H A;  1QJI A;  5L7F A;  1G05 A;  3ELM A;  2YB9 A;  3HBU P;  2ERP A;  3AYU A;  1L6J A;  4H30 A;  1RMZ A;  1O0Q A;  1Q3A A;  1JAO A;  5D7W A;  2XS3 A;  4H84 A;  3WV1 A;  4WK7 A;  3ZXH A;  4JQG A;  1YOU A;  4CTH A;  1UTT A;  4H82 A;  1IAA A;  1SLN A;  3HBV P;  4ILW D;  3CKI A;  4GWM A;  4AYK A;  1IAD A;  1R1I A;  1ATL A;  5CUH A;  4PKV A;  3O2X A;  4L63 A;  2RJQ A;  4FU4 A;  1XFZ A;  3GBO A;  1G9K A;  1OM8 A;  3HB2 P;  1JH1 A;  2DW1 A;  2WO8 A;  1FM1 A;  3OHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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