3LIRA

Human mmp12 in complex with non-zinc chelating inhibitor
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2010-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 3lirA00
1IAGA 4AYKA 1ZS0A 4FXQA 1JKYA 2X3AA 3TT4A 1AYKA 3TVCA 1KUGA 4H84A 1GE7A 4PKWA 1R55A 2JIHA 2HU6A 1GE6A 4GR3A 5I0LA 1KBCA 3LKAA 2RJQA 1OM7A 1BKCA 2MLRA 4EFSA 4H82A 2V4BA 1JIZA 2TCLA 1XFXA 1KUIA 4H3XA 1BIWA 2YIGA 3LILA 1XFVA 1PWUA 1PWVA 1JIWP 4GUYA 4GWMA 1UMSA 3LGPA 1R54A 1KUFA 1A85A 1YOUA 5L79A 3LJTA 3LK8A 3LE9A 3TS4A 1C3IA 2DW2A 2I47A 1JAOA 1YCMA 3K7NA 3HBVP 2XS4A 1CIZA 1SLMA 5JMYA 1XFUA 4G0DA 1BQQM 3ZUKA 3WV1A 2OY2A 2OW2A 1XUCA 3AYKA 2OVXA 5B5PA 1OS2A 1IACA 3F15A 3LQBA 2JSDA 2X3BA 1PWWA 3WV3A 4G9LA 5L7FA 1HV5A 2YB9A 3G5CA 1ZP5A 2E3XA 3NX7A 2CLTA 4H30A 2K9CA 1O0QA 1AF0A 3DSLA 3LJGA 4AIGA 1GKDA 3HB2P 3F1AA 2ERQA 1UMTA 1QJIA 1XURA 3P1VA 1OMJA 3EDIA 1RM8A 4A7BA 4H1QA 2OY4A 4QKZA 3KWVC 1KUHA 1ROSA 3U1RA 3L0TA 4Q1LA 1KUKA 1WNIA 2O36A 1C8TA 4DF9A 3SHIA 4FVLA 4JPAA 3E8RA 1EAKA 2DW1A 4ZR5A 3I7GA 1D8FA 3GBOA 1BUDA 3I7IA 4I35A 3CKIA 3P24A 1XFYA 3AIGA 3ZXHA 1I73A 3B92A 1A86A 3OHOA 4GR0A 4ILWD 2USNA 5B5OA 1EB6A 1PWQA 4I03A 3USNA 1CXVA 4WK7A 1I76A 1EUBA 2DDFA 1JAQA 1SMPA 2JNPA 1C7KA 1HTDA 2XS3A 1ND1A 3EWJA 2OW1A 2ERPA 3DNGA 1CQRA 3HY7A 1H71P 1OS9A 4DV8A 1CAQA 4H2EA 5BOYA 1QIAA 1HOVA 3DPEA 3KEKA 1GKCA 1XFZA 3EDGA 4JQGA 1OO9A 1Y93A 3UVCA 4PKSA 1QJJA 1YP1A 1IADA 1B3DA 3AYUA 3Q2GA 2JT6A 4CTHA 1MMRA 1BQOA 4GF1A 1OM6A 3HBUP 4IUWA 1G9KA 1Y0VA 1UEAA 1BSWA 3K7LA 2OW0A 3O64A 1ZVXA 2Y6DA 2W0DA 4XCTA 3BA0A 2CKIA 1FLSA 5I3MA 3KHIA 3LUMA 1USNA 3O2XA 1ASTA 3F19A 2DDYA 2RJPA 5BPAA 1AKLA 1G05A 2O3EA 1MMPA 1JK3A 4XM8A 3RTTA 3KMEA 4HMAA 1Z3JA 5BOTA 2OZRA 5I12A 3EDHA 3LIRA 966CA 3HY9A 4IN9A 4GWNA 3HYGA 2AYKA 4PKTA 1D7XA 4J4MA 4JIJA 1DTHA 1GO8P 2W12A 1BKCE 456CA 2OI0A 1KAPP 4PKUA 1D8MA 3EHYA 4PKVA 4A3WA 2E2DA 1ZXCA 1SRPA 3LJZA 1R1IA 1CK7A 4ON1A 1G49A 1MMQA 1OM8A 1FBLA 3V96B 2MZEA 1SU3A 2OVZA 5I4OA 1MMBA 4PKRA 3VTGA 5H8XA 5CXAA 2J83A 1Q3AA 1MNCA 1GO7P 3N2UA 4WKIA 1IAEA 2WOAA 3HDAP 2AIGP 1CGFA 1RMZA 2OXWA 1O0TA 1IABA 1K7QA 3F17A 1BZSA 4GQLA 1FM1A 4DPEA 2W13A 3WV2A 3DL1A 1CGLA 1UTTA 3G42A 5D3CA 1BUVM 4AUOA 1BM6A 3MA2A 2PJTA 3B8ZA 2A8HA 1BKCI 3EHXA 4FU4A 1G12A 4FXYP 1SATA 4H49A 3TSKA 3LQ0A 4WKEA 3OHLA 1J7NA 1R1JA 2FV9A 3KEJA 4H76A 3LEAA 4XBHA 1K7IA 3EDZA 4JA1A 5CUHA 2K2GA 2X7MA 5I43A 2MZIA 3KECA 5D1TA 4DD8A 3KRYA 3LMCA 2OW9A 2X3CA 1ZTQA 1QICA 2OXZA 3KMCA 1SLNA 2J0TA 4XM7A 1IAAA 2W15A 1HFCA 2N8RA 5D7WA 2MZHA 1QUAA 830CA 5I2ZA 1B8YA 4WZVA 3DWBA 2EROA 1JJ9A 2QPJA 4WF6A 2FV5A 1GE5A 2L0RA 3LIKA 1K7GA 1PWPA 1XUDA 4GR8A 2MLSA 1JAPA 3VI1A 5LABA 3ELMA 2POJA 5D1SA 4AXQA 4XM6A 2WO8A 3L0VA 5D2BA 1DMTA 2D1OA 2SRTA 1D5JA 5D1UA 3B2ZA 3HDBA 2OXUA 1Y8JA 2Z2DA 4L19A 2W14A 4JP4A 1HFSA 1ZXVA 1UTZA 3N2VA 2JT5A 2WO9A 2DW0A 3Q2HA 1JH1A 2D1NA 2Y6CA 3F18A 1ATLA 4L63A 1R1HA 1G4KA 1CGEA 5CZMA 4L6TA 1S4BP 4R3VA 1QIBA 1YQYA 4IJOA 1I1IP 4PKQA 3LUNA 3RTSA 3F16A 1GXDA 1L6JA 1XFWA 3ZVSA 4HX3A 2KRJA 3DPFA 1JANA 1HY7A
chains in the Genus database with same CATH superfamily
1IAGA 4AYKA 1ZS0A 4FXQA 1JKYA 2X3AA 3TT4A 1AYKA 3TVCA 1KUGA 4H84A 1GE7A 4PKWA 1R55A 2JIHA 3DTIA 2HU6A 1GE6A 4GR3A 5I0LA 1KBCA 3LKAA 2RJQA 1OM7A 1BKCA 2MLRA 4EFSA 4H82A 1TVIA 2V4BA 1JIZA 2TCLA 1XFXA 1KUIA 4H3XA 1BIWA 2YIGA 3LILA 1XFVA 1PWUA 1PWVA 1JIWP 4GUYA 4GWMA 1UMSA 3LGPA 1R54A 1KUFA 1A85A 1YOUA 5L79A 3LJTA 3LK8A 3LE9A 3TS4A 1C3IA 2DW2A 2I47A 1JAOA 1YCMA 3K7NA 3HBVP 2XS4A 1CIZA 1SLMA 5JMYA 1XFUA 4G0DA 1BQQM 3ZUKA 3WV1A 2OY2A 2OW2A 1XUCA 3AYKA 2OVXA 5B5PA 1OS2A 1IACA 1OZ9A 3F15A 3LQBA 2JSDA 2X3BA 1PWWA 3WV3A 4G9LA 5L7FA 1HV5A 2YB9A 3G5CA 1ZP5A 2E3XA 3NX7A 2CLTA 4H30A 2K9CA 1O0QA 1AF0A 3DSLA 3LJGA 4AIGA 1GKDA 3HB2P 3F1AA 2ERQA 1UMTA 1QJIA 1XURA 3P1VA 1OMJA 3EDIA 1RM8A 4A7BA 4H1QA 2OY4A 4QKZA 3KWVC 1KUHA 1ROSA 3U1RA 3L0TA 4Q1LA 1KUKA 1WNIA 2O36A 1C8TA 4DF9A 3SHIA 4FVLA 4JPAA 3E8RA 1EAKA 2DW1A 4ZR5A 3I7GA 1D8FA 3GBOA 1BUDA 3I7IA 4I35A 3CKIA 3P24A 1XFYA 3AIGA 3ZXHA 1I73A 3B92A 1A86A 3OHOA 4GR0A 4ILWD 2USNA 5B5OA 1EB6A 1PWQA 4I03A 3USNA 1CXVA 4WK7A 1I76A 3DTKA 1EUBA 2DDFA 1JAQA 1SMPA 2JNPA 1C7KA 1HTDA 2XS3A 1ND1A 3EWJA 2OW1A 2ERPA 3DNGA 1CQRA 3HY7A 1H71P 1OS9A 4DV8A 1CAQA 4H2EA 5BOYA 1QIAA 1HOVA 3DPEA 3KEKA 1GKCA 1XFZA 3EDGA 4JQGA 1OO9A 1Y93A 3UVCA 4PKSA 1QJJA 1YP1A 1IADA 1B3DA 3AYUA 3Q2GA 2JT6A 4CTHA 1MMRA 1BQOA 4GF1A 1OM6A 3HBUP 4IUWA 1G9KA 1Y0VA 1UEAA 1BSWA 3K7LA 2OW0A 3O64A 1ZVXA 2Y6DA 2W0DA 4XCTA 3BA0A 2CKIA 1FLSA 5I3MA 3KHIA 3LUMA 1XAXA 1USNA 3O2XA 1ASTA 3F19A 2DDYA 2RJPA 5BPAA 1AKLA 1G05A 3DTEA 2O3EA 1MMPA 1JK3A 4XM8A 3RTTA 3KMEA 4HMAA 1Z3JA 5BOTA 2OZRA 5I12A 3EDHA 3LIRA 966CA 3HY9A 4IN9A 4GWNA 3HYGA 2AYKA 4PKTA 1D7XA 4J4MA 4JIJA 1DTHA 1GO8P 2W12A 1BKCE 456CA 2OI0A 1KAPP 4PKUA 1D8MA 3EHYA 4PKVA 4A3WA 2E2DA 1ZXCA 1SRPA 3LJZA 1R1IA 1CK7A 4ON1A 1G49A 1MMQA 1OM8A 1FBLA 3V96B 2MZEA 1SU3A 2OVZA 5I4OA 1MMBA 4PKRA 3VTGA 5H8XA 5CXAA 2J83A 1Q3AA 1MNCA 1GO7P 3N2UA 4WKIA 1IAEA 2WOAA 3HDAP 2AIGP 1CGFA 1RMZA 2OXWA 1O0TA 1IABA 1K7QA 3F17A 1BZSA 4GQLA 1FM1A 4DPEA 2W13A 3WV2A 3DL1A 1CGLA 1UTTA 3G42A 5D3CA 1BUVM 4AUOA 1BM6A 3MA2A 2PJTA 3B8ZA 2A8HA 1BKCI 3EHXA 4FU4A 1G12A 4FXYP 1SATA 4H49A 3TSKA 3LQ0A 4WKEA 3OHLA 1J7NA 4L7AA 1R1JA 2FV9A 3KEJA 4H76A 3LEAA 4XBHA 1K7IA 3EDZA 4JA1A 5CUHA 2K2GA 2X7MA 5I43A 2MZIA 3KECA 5D1TA 4DD8A 3KRYA 3LMCA 2OW9A 2YUFA 2X3CA 1ZTQA 1QICA 2OXZA 3KMCA 1SLNA 2J0TA 4XM7A 1IAAA 2W15A 1HFCA 2N8RA 5D7WA 2MZHA 1QUAA 830CA 5I2ZA 1B8YA 4WZVA 3DWBA 2EROA 1JJ9A 2QPJA 4WF6A 2FV5A 1GE5A 2L0RA 3LIKA 1K7GA 1PWPA 1XUDA 4GR8A 2MLSA 1JAPA 3VI1A 5LABA 3ELMA 2POJA 5D1SA 4AXQA 4XM6A 2WO8A 3L0VA 5D2BA 1DMTA 2D1OA 2SRTA 1D5JA 5D1UA 3B2ZA 3HDBA 2OXUA 1Y8JA 2Z2DA 4L19A 2W14A 4JP4A 1HFSA 1ZXVA 1UTZA 3N2VA 2JT5A 2WO9A 1XM5A 2DW0A 3Q2HA 1JH1A 2D1NA 2Y6CA 3F18A 1ATLA 4L63A 1R1HA 1G4KA 1CGEA 5CZMA 4L6TA 1S4BP 4R3VA 1QIBA 1YQYA 4IJOA 1I1IP 4PKQA 3LUNA 3RTSA 3F16A 1GXDA 1L6JA 1XFWA 3ZVSA 4HX3A 2KRJA 3DPFA 1JANA 1HY7A
chains in the Genus database with same CATH topology
1IAGA 4AYKA 1ZS0A 4FXQA 1JKYA 2X3AA 3TT4A 1AYKA 3TVCA 1KUGA 4H84A 1GE7A 4PKWA 1R55A 2JIHA 3DTIA 2HU6A 1GE6A 4GR3A 5I0LA 1KBCA 3LKAA 2RJQA 1OM7A 1BKCA 2MLRA 4EFSA 4H82A 2V4BA 1JIZA 2TCLA 1XFXA 1KUIA 4H3XA 1BIWA 2YIGA 3LILA 1XFVA 1PWUA 1PWVA 1JIWP 4GUYA 4GWMA 1UMSA 3LGPA 1R54A 1KUFA 1A85A 1YOUA 5L79A 3LJTA 3LK8A 3LE9A 3TS4A 1C3IA 2DW2A 2I47A 1JAOA 1YCMA 3K7NA 3HBVP 2XS4A 1CIZA 1SLMA 5JMYA 1XFUA 4G0DA 1BQQM 3ZUKA 3WV1A 2OY2A 2OW2A 1XUCA 3AYKA 2OVXA 5B5PA 1OS2A 1IACA 3F15A 3LQBA 2JSDA 2X3BA 1PWWA 3WV3A 4G9LA 5L7FA 1HV5A 2YB9A 3G5CA 1ZP5A 2E3XA 3NX7A 2CLTA 4H30A 2K9CA 1O0QA 1AF0A 3DSLA 3LJGA 4AIGA 1GKDA 3HB2P 3F1AA 2ERQA 1UMTA 1QJIA 1XURA 3P1VA 1OMJA 3EDIA 1RM8A 4A7BA 4H1QA 2OY4A 4QKZA 3KWVC 1KUHA 1ROSA 3U1RA 3L0TA 4Q1LA 1KUKA 1WNIA 2O36A 1C8TA 4DF9A 3SHIA 4FVLA 4JPAA 3E8RA 1EAKA 2DW1A 4ZR5A 3I7GA 1D8FA 3GBOA 1BUDA 3I7IA 4I35A 3CKIA 3P24A 1XFYA 3AIGA 3ZXHA 1I73A 3B92A 1A86A 3OHOA 4GR0A 4ILWD 2USNA 5B5OA 1EB6A 1PWQA 4I03A 3USNA 1CXVA 4WK7A 1I76A 3DTKA 1EUBA 2DDFA 1JAQA 1SMPA 2JNPA 1C7KA 1HTDA 2XS3A 1ND1A 3EWJA 2OW1A 2ERPA 3DNGA 1CQRA 3HY7A 1H71P 1OS9A 4DV8A 1CAQA 4H2EA 5BOYA 1QIAA 1HOVA 3DPEA 3KEKA 1GKCA 1XFZA 3EDGA 4JQGA 1OO9A 1Y93A 3UVCA 4PKSA 1QJJA 1YP1A 1IADA 1B3DA 3AYUA 3Q2GA 2JT6A 4CTHA 1MMRA 1BQOA 4GF1A 1OM6A 3HBUP 4IUWA 1G9KA 1Y0VA 1UEAA 1BSWA 3K7LA 2OW0A 3O64A 1ZVXA 2Y6DA 2W0DA 4XCTA 3BA0A 2CKIA 1FLSA 5I3MA 3KHIA 3LUMA 1USNA 3O2XA 1ASTA 3F19A 2DDYA 2RJPA 5BPAA 1AKLA 1G05A 3DTEA 2O3EA 1MMPA 1JK3A 4XM8A 3RTTA 3KMEA 4HMAA 1Z3JA 5BOTA 2OZRA 5I12A 3EDHA 3LIRA 966CA 3HY9A 4IN9A 4GWNA 3HYGA 2AYKA 4PKTA 1D7XA 4J4MA 4JIJA 1DTHA 1GO8P 2W12A 1BKCE 456CA 2OI0A 1KAPP 4PKUA 1D8MA 3EHYA 4PKVA 4A3WA 2E2DA 1ZXCA 1SRPA 3LJZA 1R1IA 1CK7A 4ON1A 1G49A 1MMQA 1OM8A 1FBLA 3V96B 2MZEA 1SU3A 2OVZA 5I4OA 1MMBA 4PKRA 3VTGA 5H8XA 5CXAA 2J83A 1Q3AA 1MNCA 1GO7P 3N2UA 4WKIA 1IAEA 2WOAA 3HDAP 2AIGP 1CGFA 1RMZA 2OXWA 1O0TA 1IABA 1K7QA 3F17A 1BZSA 4GQLA 1FM1A 4DPEA 2W13A 3WV2A 3DL1A 1CGLA 1UTTA 3G42A 5D3CA 1BUVM 4AUOA 1BM6A 3MA2A 2PJTA 3B8ZA 2A8HA 1BKCI 3EHXA 4FU4A 1G12A 4FXYP 1SATA 4H49A 3TSKA 3LQ0A 4WKEA 3OHLA 1J7NA 4L7AA 1R1JA 2FV9A 3KEJA 4H76A 3LEAA 4XBHA 1K7IA 3EDZA 4JA1A 5CUHA 2K2GA 2X7MA 5I43A 2MZIA 3KECA 5D1TA 4DD8A 3KRYA 3LMCA 2OW9A 2YUFA 2X3CA 1ZTQA 1QICA 2OXZA 3KMCA 1SLNA 2J0TA 4XM7A 1IAAA 2W15A 1HFCA 2N8RA 5D7WA 2MZHA 1QUAA 830CA 5I2ZA 1B8YA 4WZVA 3DWBA 2EROA 1JJ9A 2QPJA 4WF6A 2FV5A 1GE5A 2L0RA 3LIKA 1K7GA 1PWPA 1XUDA 4GR8A 2MLSA 1JAPA 3VI1A 5LABA 3ELMA 2POJA 5D1SA 4AXQA 4XM6A 2WO8A 3L0VA 5D2BA 1DMTA 2D1OA 2SRTA 1D5JA 5D1UA 3B2ZA 3HDBA 2OXUA 1Y8JA 2Z2DA 4L19A 2W14A 4JP4A 1HFSA 1ZXVA 1UTZA 3N2VA 2JT5A 2WO9A 2DW0A 3Q2HA 1JH1A 2D1NA 2Y6CA 3F18A 1ATLA 4L63A 1R1HA 1G4KA 1CGEA 5CZMA 4L6TA 1S4BP 4R3VA 1QIBA 1YQYA 4IJOA 1I1IP 4PKQA 3LUNA 3RTSA 3F16A 1GXDA 1L6JA 1XFWA 3ZVSA 4HX3A 2KRJA 3DPFA 1JANA 1HY7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IAG A;  4AYK A;  1ZS0 A;  4FXQ A;  1JKY A;  2X3A A;  3TT4 A;  1AYK A;  3TVC A;  1KUG A;  4H84 A;  1GE7 A;  4PKW A;  1R55 A;  2JIH A;  2HU6 A;  1GE6 A;  4GR3 A;  5I0L A;  1KBC A;  3LKA A;  2RJQ A;  1OM7 A;  1BKC A;  2MLR A;  4EFS A;  4H82 A;  2V4B A;  1JIZ A;  2TCL A;  1XFX A;  1KUI A;  4H3X A;  1BIW A;  2YIG A;  3LIL A;  1XFV A;  1PWU A;  1PWV A;  1JIW P;  4GUY A;  4GWM A;  1UMS A;  3LGP A;  1R54 A;  1KUF A;  1A85 A;  1YOU A;  5L79 A;  3LJT A;  3LK8 A;  3LE9 A;  3TS4 A;  1C3I A;  2DW2 A;  2I47 A;  1JAO A;  1YCM A;  3K7N A;  3HBV P;  2XS4 A;  1CIZ A;  1SLM A;  5JMY A;  1XFU A;  4G0D A;  1BQQ M;  3ZUK A;  3WV1 A;  2OY2 A;  2OW2 A;  1XUC A;  3AYK A;  2OVX A;  5B5P A;  1OS2 A;  1IAC A;  3F15 A;  3LQB A;  2JSD A;  2X3B A;  1PWW A;  3WV3 A;  4G9L A;  5L7F A;  1HV5 A;  2YB9 A;  3G5C A;  1ZP5 A;  2E3X A;  3NX7 A;  2CLT A;  4H30 A;  2K9C A;  1O0Q A;  1AF0 A;  3DSL A;  3LJG A;  4AIG A;  1GKD A;  3HB2 P;  3F1A A;  2ERQ A;  1UMT A;  1QJI A;  1XUR A;  3P1V A;  1OMJ A;  3EDI A;  1RM8 A;  4A7B A;  4H1Q A;  2OY4 A;  4QKZ A;  3KWV C;  1KUH A;  1ROS A;  3U1R A;  3L0T A;  4Q1L A;  1KUK A;  1WNI A;  2O36 A;  1C8T A;  4DF9 A;  3SHI A;  4FVL A;  4JPA A;  3E8R A;  1EAK A;  2DW1 A;  4ZR5 A;  3I7G A;  1D8F A;  3GBO A;  1BUD A;  3I7I A;  4I35 A;  3CKI A;  3P24 A;  1XFY A;  3AIG A;  3ZXH A;  1I73 A;  3B92 A;  1A86 A;  3OHO A;  4GR0 A;  4ILW D;  2USN A;  5B5O A;  1EB6 A;  1PWQ A;  4I03 A;  3USN A;  1CXV A;  4WK7 A;  1I76 A;  1EUB A;  2DDF A;  1JAQ A;  1SMP A;  2JNP A;  1C7K A;  1HTD A;  2XS3 A;  1ND1 A;  3EWJ A;  2OW1 A;  2ERP A;  3DNG A;  1CQR A;  3HY7 A;  1H71 P;  1OS9 A;  4DV8 A;  1CAQ A;  4H2E A;  5BOY A;  1QIA A;  1HOV A;  3DPE A;  3KEK A;  1GKC A;  1XFZ A;  3EDG A;  4JQG A;  1OO9 A;  1Y93 A;  3UVC A;  4PKS A;  1QJJ A;  1YP1 A;  1IAD A;  1B3D A;  3AYU A;  3Q2G A;  2JT6 A;  4CTH A;  1MMR A;  1BQO A;  4GF1 A;  1OM6 A;  3HBU P;  4IUW A;  1G9K A;  1Y0V A;  1UEA A;  1BSW A;  3K7L A;  2OW0 A;  3O64 A;  1ZVX A;  2Y6D A;  2W0D A;  4XCT A;  3BA0 A;  2CKI A;  1FLS A;  5I3M A;  3KHI A;  3LUM A;  1USN A;  3O2X A;  1AST A;  3F19 A;  2DDY A;  2RJP A;  5BPA A;  1AKL A;  1G05 A;  2O3E A;  1MMP A;  1JK3 A;  4XM8 A;  3RTT A;  3KME A;  4HMA A;  1Z3J A;  5BOT A;  2OZR A;  5I12 A;  3EDH A;  3LIR A;  966C A;  3HY9 A;  4IN9 A;  4GWN A;  3HYG A;  2AYK A;  4PKT A;  1D7X A;  4J4M A;  4JIJ A;  1DTH A;  1GO8 P;  2W12 A;  1BKC E;  456C A;  2OI0 A;  1KAP P;  4PKU A;  1D8M A;  3EHY A;  4PKV A;  4A3W A;  2E2D A;  1ZXC A;  1SRP A;  3LJZ A;  1R1I A;  1CK7 A;  4ON1 A;  1G49 A;  1MMQ A;  1OM8 A;  1FBL A;  3V96 B;  2MZE A;  1SU3 A;  2OVZ A;  5I4O A;  1MMB A;  4PKR A;  3VTG A;  5H8X A;  5CXA A;  2J83 A;  1Q3A A;  1MNC A;  1GO7 P;  3N2U A;  4WKI A;  1IAE A;  2WOA A;  3HDA P;  2AIG P;  1CGF A;  1RMZ A;  2OXW A;  1O0T A;  1IAB A;  1K7Q A;  3F17 A;  1BZS A;  4GQL A;  1FM1 A;  4DPE A;  2W13 A;  3WV2 A;  3DL1 A;  1CGL A;  1UTT A;  3G42 A;  5D3C A;  1BUV M;  4AUO A;  1BM6 A;  3MA2 A;  2PJT A;  3B8Z A;  2A8H A;  1BKC I;  3EHX A;  4FU4 A;  1G12 A;  4FXY P;  1SAT A;  4H49 A;  3TSK A;  3LQ0 A;  4WKE A;  3OHL A;  1J7N A;  1R1J A;  2FV9 A;  3KEJ A;  4H76 A;  3LEA A;  4XBH A;  1K7I A;  3EDZ A;  4JA1 A;  5CUH A;  2K2G A;  2X7M A;  5I43 A;  2MZI A;  3KEC A;  5D1T A;  4DD8 A;  3KRY A;  3LMC A;  2OW9 A;  2X3C A;  1ZTQ A;  1QIC A;  2OXZ A;  3KMC A;  1SLN A;  2J0T A;  4XM7 A;  1IAA A;  2W15 A;  1HFC A;  2N8R A;  5D7W A;  2MZH A;  1QUA A;  830C A;  5I2Z A;  1B8Y A;  4WZV A;  3DWB A;  2ERO A;  1JJ9 A;  2QPJ A;  4WF6 A;  2FV5 A;  1GE5 A;  2L0R A;  3LIK A;  1K7G A;  1PWP A;  1XUD A;  4GR8 A;  2MLS A;  1JAP A;  3VI1 A;  5LAB A;  3ELM A;  2POJ A;  5D1S A;  4AXQ A;  4XM6 A;  2WO8 A;  3L0V A;  5D2B A;  1DMT A;  2D1O A;  2SRT A;  1D5J A;  5D1U A;  3B2Z A;  3HDB A;  2OXU A;  1Y8J A;  2Z2D A;  4L19 A;  2W14 A;  4JP4 A;  1HFS A;  1ZXV A;  1UTZ A;  3N2V A;  2JT5 A;  2WO9 A;  2DW0 A;  3Q2H A;  1JH1 A;  2D1N A;  2Y6C A;  3F18 A;  1ATL A;  4L63 A;  1R1H A;  1G4K A;  1CGE A;  5CZM A;  4L6T A;  1S4B P;  4R3V A;  1QIB A;  1YQY A;  4IJO A;  1I1I P;  4PKQ A;  3LUN A;  3RTS A;  3F16 A;  1GXD A;  1L6J A;  1XFW A;  3ZVS A;  4HX3 A;  2KRJ A;  3DPF A;  1JAN A;  1HY7 A; 
#chains in the Genus database with same CATH topology
 1IAG A;  4AYK A;  1ZS0 A;  4FXQ A;  1JKY A;  2X3A A;  3TT4 A;  1AYK A;  3TVC A;  1KUG A;  4H84 A;  1GE7 A;  4PKW A;  1R55 A;  2JIH A;  3DTI A;  2HU6 A;  1GE6 A;  4GR3 A;  5I0L A;  1KBC A;  3LKA A;  2RJQ A;  1OM7 A;  1BKC A;  2MLR A;  4EFS A;  4H82 A;  1TVI A;  2V4B A;  1JIZ A;  2TCL A;  1XFX A;  1KUI A;  4H3X A;  1BIW A;  2YIG A;  3LIL A;  1XFV A;  1PWU A;  1PWV A;  1JIW P;  4GUY A;  4GWM A;  1UMS A;  3LGP A;  1R54 A;  1KUF A;  1A85 A;  1YOU A;  5L79 A;  3LJT A;  3LK8 A;  3LE9 A;  3TS4 A;  1C3I A;  2DW2 A;  2I47 A;  1JAO A;  1YCM A;  3K7N A;  3HBV P;  2XS4 A;  1CIZ A;  1SLM A;  5JMY A;  1XFU A;  4G0D A;  1BQQ M;  3ZUK A;  3WV1 A;  2OY2 A;  2OW2 A;  1XUC A;  3AYK A;  2OVX A;  5B5P A;  1OS2 A;  1IAC A;  1OZ9 A;  3F15 A;  3LQB A;  2JSD A;  2X3B A;  1PWW A;  3WV3 A;  4G9L A;  5L7F A;  1HV5 A;  2YB9 A;  3G5C A;  1ZP5 A;  2E3X A;  3NX7 A;  2CLT A;  4H30 A;  2K9C A;  1O0Q A;  1AF0 A;  3DSL A;  3LJG A;  4AIG A;  1GKD A;  3HB2 P;  3F1A A;  2ERQ A;  1UMT A;  1QJI A;  1XUR A;  3P1V A;  1OMJ A;  3EDI A;  1RM8 A;  4A7B A;  4H1Q A;  2OY4 A;  4QKZ A;  3KWV C;  1KUH A;  1ROS A;  3U1R A;  3L0T A;  4Q1L A;  1KUK A;  1WNI A;  2O36 A;  1C8T A;  4DF9 A;  3SHI A;  4FVL A;  4JPA A;  3E8R A;  1EAK A;  2DW1 A;  4ZR5 A;  3I7G A;  1D8F A;  3GBO A;  1BUD A;  3I7I A;  4I35 A;  3CKI A;  3P24 A;  1XFY A;  3AIG A;  3ZXH A;  1I73 A;  3B92 A;  1A86 A;  3OHO A;  4GR0 A;  4ILW D;  2USN A;  5B5O A;  1EB6 A;  1PWQ A;  4I03 A;  3USN A;  1CXV A;  4WK7 A;  1I76 A;  3DTK A;  1EUB A;  2DDF A;  1JAQ A;  1SMP A;  2JNP A;  1C7K A;  1HTD A;  2XS3 A;  1ND1 A;  3EWJ A;  2OW1 A;  2ERP A;  3DNG A;  1CQR A;  3HY7 A;  1H71 P;  1OS9 A;  4DV8 A;  1CAQ A;  4H2E A;  5BOY A;  1QIA A;  1HOV A;  3DPE A;  3KEK A;  1GKC A;  1XFZ A;  3EDG A;  4JQG A;  1OO9 A;  1Y93 A;  3UVC A;  4PKS A;  1QJJ A;  1YP1 A;  1IAD A;  1B3D A;  3AYU A;  3Q2G A;  2JT6 A;  4CTH A;  1MMR A;  1BQO A;  4GF1 A;  1OM6 A;  3HBU P;  4IUW A;  1G9K A;  1Y0V A;  1UEA A;  1BSW A;  3K7L A;  2OW0 A;  3O64 A;  1ZVX A;  2Y6D A;  2W0D A;  4XCT A;  3BA0 A;  2CKI A;  1FLS A;  5I3M A;  3KHI A;  3LUM A;  1XAX A;  1USN A;  3O2X A;  1AST A;  3F19 A;  2DDY A;  2RJP A;  5BPA A;  1AKL A;  1G05 A;  3DTE A;  2O3E A;  1MMP A;  1JK3 A;  4XM8 A;  3RTT A;  3KME A;  4HMA A;  1Z3J A;  5BOT A;  2OZR A;  5I12 A;  3EDH A;  3LIR A;  966C A;  3HY9 A;  4IN9 A;  4GWN A;  3HYG A;  2AYK A;  4PKT A;  1D7X A;  4J4M A;  4JIJ A;  1DTH A;  1GO8 P;  2W12 A;  1BKC E;  456C A;  2OI0 A;  1KAP P;  4PKU A;  1D8M A;  3EHY A;  4PKV A;  4A3W A;  2E2D A;  1ZXC A;  1SRP A;  3LJZ A;  1R1I A;  1CK7 A;  4ON1 A;  1G49 A;  1MMQ A;  1OM8 A;  1FBL A;  3V96 B;  2MZE A;  1SU3 A;  2OVZ A;  5I4O A;  1MMB A;  4PKR A;  3VTG A;  5H8X A;  5CXA A;  2J83 A;  1Q3A A;  1MNC A;  1GO7 P;  3N2U A;  4WKI A;  1IAE A;  2WOA A;  3HDA P;  2AIG P;  1CGF A;  1RMZ A;  2OXW A;  1O0T A;  1IAB A;  1K7Q A;  3F17 A;  1BZS A;  4GQL A;  1FM1 A;  4DPE A;  2W13 A;  3WV2 A;  3DL1 A;  1CGL A;  1UTT A;  3G42 A;  5D3C A;  1BUV M;  4AUO A;  1BM6 A;  3MA2 A;  2PJT A;  3B8Z A;  2A8H A;  1BKC I;  3EHX A;  4FU4 A;  1G12 A;  4FXY P;  1SAT A;  4H49 A;  3TSK A;  3LQ0 A;  4WKE A;  3OHL A;  1J7N A;  4L7A A;  1R1J A;  2FV9 A;  3KEJ A;  4H76 A;  3LEA A;  4XBH A;  1K7I A;  3EDZ A;  4JA1 A;  5CUH A;  2K2G A;  2X7M A;  5I43 A;  2MZI A;  3KEC A;  5D1T A;  4DD8 A;  3KRY A;  3LMC A;  2OW9 A;  2YUF A;  2X3C A;  1ZTQ A;  1QIC A;  2OXZ A;  3KMC A;  1SLN A;  2J0T A;  4XM7 A;  1IAA A;  2W15 A;  1HFC A;  2N8R A;  5D7W A;  2MZH A;  1QUA A;  830C A;  5I2Z A;  1B8Y A;  4WZV A;  3DWB A;  2ERO A;  1JJ9 A;  2QPJ A;  4WF6 A;  2FV5 A;  1GE5 A;  2L0R A;  3LIK A;  1K7G A;  1PWP A;  1XUD A;  4GR8 A;  2MLS A;  1JAP A;  3VI1 A;  5LAB A;  3ELM A;  2POJ A;  5D1S A;  4AXQ A;  4XM6 A;  2WO8 A;  3L0V A;  5D2B A;  1DMT A;  2D1O A;  2SRT A;  1D5J A;  5D1U A;  3B2Z A;  3HDB A;  2OXU A;  1Y8J A;  2Z2D A;  4L19 A;  2W14 A;  4JP4 A;  1HFS A;  1ZXV A;  1UTZ A;  3N2V A;  2JT5 A;  2WO9 A;  1XM5 A;  2DW0 A;  3Q2H A;  1JH1 A;  2D1N A;  2Y6C A;  3F18 A;  1ATL A;  4L63 A;  1R1H A;  1G4K A;  1CGE A;  5CZM A;  4L6T A;  1S4B P;  4R3V A;  1QIB A;  1YQY A;  4IJO A;  1I1I P;  4PKQ A;  3LUN A;  3RTS A;  3F16 A;  1GXD A;  1L6J A;  1XFW A;  3ZVS A;  4HX3 A;  2KRJ A;  3DPF A;  1JAN A;  1HY7 A; 
#chains in the Genus database with same CATH homology
 1IAG A;  4AYK A;  1ZS0 A;  4FXQ A;  1JKY A;  2X3A A;  3TT4 A;  1AYK A;  3TVC A;  1KUG A;  4H84 A;  1GE7 A;  4PKW A;  1R55 A;  2JIH A;  3DTI A;  2HU6 A;  1GE6 A;  4GR3 A;  5I0L A;  1KBC A;  3LKA A;  2RJQ A;  1OM7 A;  1BKC A;  2MLR A;  4EFS A;  4H82 A;  2V4B A;  1JIZ A;  2TCL A;  1XFX A;  1KUI A;  4H3X A;  1BIW A;  2YIG A;  3LIL A;  1XFV A;  1PWU A;  1PWV A;  1JIW P;  4GUY A;  4GWM A;  1UMS A;  3LGP A;  1R54 A;  1KUF A;  1A85 A;  1YOU A;  5L79 A;  3LJT A;  3LK8 A;  3LE9 A;  3TS4 A;  1C3I A;  2DW2 A;  2I47 A;  1JAO A;  1YCM A;  3K7N A;  3HBV P;  2XS4 A;  1CIZ A;  1SLM A;  5JMY A;  1XFU A;  4G0D A;  1BQQ M;  3ZUK A;  3WV1 A;  2OY2 A;  2OW2 A;  1XUC A;  3AYK A;  2OVX A;  5B5P A;  1OS2 A;  1IAC A;  3F15 A;  3LQB A;  2JSD A;  2X3B A;  1PWW A;  3WV3 A;  4G9L A;  5L7F A;  1HV5 A;  2YB9 A;  3G5C A;  1ZP5 A;  2E3X A;  3NX7 A;  2CLT A;  4H30 A;  2K9C A;  1O0Q A;  1AF0 A;  3DSL A;  3LJG A;  4AIG A;  1GKD A;  3HB2 P;  3F1A A;  2ERQ A;  1UMT A;  1QJI A;  1XUR A;  3P1V A;  1OMJ A;  3EDI A;  1RM8 A;  4A7B A;  4H1Q A;  2OY4 A;  4QKZ A;  3KWV C;  1KUH A;  1ROS A;  3U1R A;  3L0T A;  4Q1L A;  1KUK A;  1WNI A;  2O36 A;  1C8T A;  4DF9 A;  3SHI A;  4FVL A;  4JPA A;  3E8R A;  1EAK A;  2DW1 A;  4ZR5 A;  3I7G A;  1D8F A;  3GBO A;  1BUD A;  3I7I A;  4I35 A;  3CKI A;  3P24 A;  1XFY A;  3AIG A;  3ZXH A;  1I73 A;  3B92 A;  1A86 A;  3OHO A;  4GR0 A;  4ILW D;  2USN A;  5B5O A;  1EB6 A;  1PWQ A;  4I03 A;  3USN A;  1CXV A;  4WK7 A;  1I76 A;  3DTK A;  1EUB A;  2DDF A;  1JAQ A;  1SMP A;  2JNP A;  1C7K A;  1HTD A;  2XS3 A;  1ND1 A;  3EWJ A;  2OW1 A;  2ERP A;  3DNG A;  1CQR A;  3HY7 A;  1H71 P;  1OS9 A;  4DV8 A;  1CAQ A;  4H2E A;  5BOY A;  1QIA A;  1HOV A;  3DPE A;  3KEK A;  1GKC A;  1XFZ A;  3EDG A;  4JQG A;  1OO9 A;  1Y93 A;  3UVC A;  4PKS A;  1QJJ A;  1YP1 A;  1IAD A;  1B3D A;  3AYU A;  3Q2G A;  2JT6 A;  4CTH A;  1MMR A;  1BQO A;  4GF1 A;  1OM6 A;  3HBU P;  4IUW A;  1G9K A;  1Y0V A;  1UEA A;  1BSW A;  3K7L A;  2OW0 A;  3O64 A;  1ZVX A;  2Y6D A;  2W0D A;  4XCT A;  3BA0 A;  2CKI A;  1FLS A;  5I3M A;  3KHI A;  3LUM A;  1USN A;  3O2X A;  1AST A;  3F19 A;  2DDY A;  2RJP A;  5BPA A;  1AKL A;  1G05 A;  3DTE A;  2O3E A;  1MMP A;  1JK3 A;  4XM8 A;  3RTT A;  3KME A;  4HMA A;  1Z3J A;  5BOT A;  2OZR A;  5I12 A;  3EDH A;  3LIR A;  966C A;  3HY9 A;  4IN9 A;  4GWN A;  3HYG A;  2AYK A;  4PKT A;  1D7X A;  4J4M A;  4JIJ A;  1DTH A;  1GO8 P;  2W12 A;  1BKC E;  456C A;  2OI0 A;  1KAP P;  4PKU A;  1D8M A;  3EHY A;  4PKV A;  4A3W A;  2E2D A;  1ZXC A;  1SRP A;  3LJZ A;  1R1I A;  1CK7 A;  4ON1 A;  1G49 A;  1MMQ A;  1OM8 A;  1FBL A;  3V96 B;  2MZE A;  1SU3 A;  2OVZ A;  5I4O A;  1MMB A;  4PKR A;  3VTG A;  5H8X A;  5CXA A;  2J83 A;  1Q3A A;  1MNC A;  1GO7 P;  3N2U A;  4WKI A;  1IAE A;  2WOA A;  3HDA P;  2AIG P;  1CGF A;  1RMZ A;  2OXW A;  1O0T A;  1IAB A;  1K7Q A;  3F17 A;  1BZS A;  4GQL A;  1FM1 A;  4DPE A;  2W13 A;  3WV2 A;  3DL1 A;  1CGL A;  1UTT A;  3G42 A;  5D3C A;  1BUV M;  4AUO A;  1BM6 A;  3MA2 A;  2PJT A;  3B8Z A;  2A8H A;  1BKC I;  3EHX A;  4FU4 A;  1G12 A;  4FXY P;  1SAT A;  4H49 A;  3TSK A;  3LQ0 A;  4WKE A;  3OHL A;  1J7N A;  4L7A A;  1R1J A;  2FV9 A;  3KEJ A;  4H76 A;  3LEA A;  4XBH A;  1K7I A;  3EDZ A;  4JA1 A;  5CUH A;  2K2G A;  2X7M A;  5I43 A;  2MZI A;  3KEC A;  5D1T A;  4DD8 A;  3KRY A;  3LMC A;  2OW9 A;  2YUF A;  2X3C A;  1ZTQ A;  1QIC A;  2OXZ A;  3KMC A;  1SLN A;  2J0T A;  4XM7 A;  1IAA A;  2W15 A;  1HFC A;  2N8R A;  5D7W A;  2MZH A;  1QUA A;  830C A;  5I2Z A;  1B8Y A;  4WZV A;  3DWB A;  2ERO A;  1JJ9 A;  2QPJ A;  4WF6 A;  2FV5 A;  1GE5 A;  2L0R A;  3LIK A;  1K7G A;  1PWP A;  1XUD A;  4GR8 A;  2MLS A;  1JAP A;  3VI1 A;  5LAB A;  3ELM A;  2POJ A;  5D1S A;  4AXQ A;  4XM6 A;  2WO8 A;  3L0V A;  5D2B A;  1DMT A;  2D1O A;  2SRT A;  1D5J A;  5D1U A;  3B2Z A;  3HDB A;  2OXU A;  1Y8J A;  2Z2D A;  4L19 A;  2W14 A;  4JP4 A;  1HFS A;  1ZXV A;  1UTZ A;  3N2V A;  2JT5 A;  2WO9 A;  2DW0 A;  3Q2H A;  1JH1 A;  2D1N A;  2Y6C A;  3F18 A;  1ATL A;  4L63 A;  1R1H A;  1G4K A;  1CGE A;  5CZM A;  4L6T A;  1S4B P;  4R3V A;  1QIB A;  1YQY A;  4IJO A;  1I1I P;  4PKQ A;  3LUN A;  3RTS A;  3F16 A;  1GXD A;  1L6J A;  1XFW A;  3ZVS A;  4HX3 A;  2KRJ A;  3DPF A;  1JAN A;  1HY7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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