3LK2A

Crystal structure of capz bound to the uncapping motif from carmil
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
270
structure length
270
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
source organism Gallus gallus
molecule tags Protein binding
molecule keywords F-actin-capping protein subunit alpha-1
total genus 80
structure length 270
sequence length 270
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk2A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk2A02
3AA0A 3AA6B 2KXPB 3AA6A 3AA0B 5ADXL 3LK42 5AFUL 5ADXK 3AA1A 1IZNB 3AA7B 3AA7A 3LK2B 3AAEB 3AAEA 3LK3B 3LK2A 3AAAB 2KZ7B 1IZNA 3AA1B 5AFUK 4AKRA 3AAAA 4AKRB 2KZ7A 2KXPA 3LK41 3LK3A
chains in the Genus database with same CATH superfamily
4IL6O 2LFUA 3SZDA 4AYID 2KXPB 4RLBA 5TISO 4LSFA 3T24A 4GCPA 5B5EO 3AA0B 2JMMA 2JQYA 2ES9A 2Y7SA 4FZMA 2ERVA 3SY7A 1OPFA 4K3CA 3A0BO 1IZNB 3AA7B 2R4LA 2LHFA 1Q9FA 2QTKA 4D65A 4PJ0O 4QQ1A 2O4VA 3UPGA 3HWBA 4O3YA 5G26A 2Q0TA 2PFXA 1ZHYA 3JTYA 3PF1A 2R4OA 3NJTA 4GF4A 4RJWA 5G38A 2J1NA 1Q9GA 4FESA 5DL8A 1MPFA 5KAFO 4FSPA 4C69X 2PRNA 3KZIO 4C4VA 1G90A 2WJRA 5DL7A 1LW1A 2IJCA 2XE1A 2AF7A 4FOZA 3WI5A 4G75A 3HOLA 3POUA 1GFPA 4JCHA 4PR7A 5DL6A 3VE1A 4AKRA 3A0HO 3NSGA 3BRYA 1HXXA 2KZ7A 2KXPA 1QJPA 1ME5A 3BRZA 3PGRA 3C5OA 5E79O 4E1SA 2N2MA 2Y0LA 4N75A 3PGUA 4KRAA 2WVPA 3PORA 5D5DA 2J4UP 2XTQA 4LSIA 2KDYA 4U9CA 5GTIO 3V8UA 3EMNX 1BH3A 1GFQA 3SZVA 2XE3A 4AFKA 3LK42 3RBHA 4D64A 8PRNA 4Z3TA 1ZHTA 5ADXK 5B66O 2OYOA 2KC0A 2MHLA 4C00A 4GCSA 2Y2XA 2WJQA 3PQSA 2PRRA 2N2LA 3DZMA 3VZTX 3PGSA 5T5FA 2M06A 4AKMA 5H2FO 2M07A 2R4PA 3FYXA 3K19A 4D5UA 3LK3B 3BEYA 3WU2O 2YPVA 2CWQA 1GFOA 2PORA 3SYBA 1P4TA 1ZHXA 1E54A 2IWVA 2MNHA 4FQEA 4XNLA 4AYDC 1IZNA 1QJ9A 2GE4A 4E1TA 2XTRA 1VKEA 2X27X 2JN8A 3DWOX 4LSHA 4FRTA 3AAAA 1PHOA 5G39A 3VZUX 4C4VB 2IWWA 3QRCA 4AKRB 2F1CX 3AA0A 2FGQX 3DA4A 1QJ8A 4G76A 1KNCA 4LSEA 5FVNA 5PRNA 3POQA 1GFMA 3SY9A 2XE5A 3VY8X 1BXWA 1S5LO 4FUVA 2QEUA 3BS0A 4K3BA 4O4XA 3VZWX 3G7GA 4N59A 5GV0A 5ADXL 2GMYA 3LVYA 4CTDA 2Y0KA 3GP6A 4AYMC 3AA1A 4O3WA 2YNKA 5JDPA 5DL5A 3D7IA 3HW9A 3AA7A 1ORMA 1T16A 3DWNA 4XNKA 4UB6O 3KVDD 3T0SA 2ODJA 5IYUA 2F1TA 2K0LA 2R4NA 4RJXA 4N58A 4RLCA 2W81C 4GCQA 3JCUO 1MM5A 5DIPA 2K4TA 3QRAA 3LK2A 2O4DA 1ZHWA 3O0EA 4PUXA 2Y0HA 3AAAB 4FZNA 6PRNA 3A2SX 2ZLDA 4RL9A 1HXTA 2OUWA 3PQUA 2W80C 5AFUL 3VE2A 7PRNA 3LK3A 4UB8O 3UU2A 3AA6B 4BUMX 1MM4A 3SYSA 4B61A 1T1LA 2OMFA 2R89A 2ZFGA 4FMSA 3POXA 3C1LA 1YS5A 4N74A 1GU9A 4G9QA 2XG6A 3AA6A 4GHBA 1OSMA 2R88A 4KR4A 4FRXA 5DIKA 4FZLA 2XE2A 5EE2A 5KAIO 4O3ZA 3WI4A 2AXTO 5G3AA 4O3XB 4KR8A 2XMXA 4O49A 3TZGA 4AUIA 2FGRA 1GFNA 4FSOA 4AYNA 3T20A 1P8CA 3LK2B 3VY9X 2R8AA 3AAEB 1H6S1 3AAEA 3PRNA 3DA3A 1PRNA 3UAQA 4F4BA 1THQA 4FT6A 1ZHZA 2KZ7B 3HOEA 2F1VA 3AA1B 2X9KA 4O4UA 4AYEC 4JFBA 5GTHO 5AFUK 4AZLA 1HXUA 1BT9A 3LK41
chains in the Genus database with same CATH topology
2LFUA 3SZDA 4AYID 2KXPB 4RLBA 3T24A 4LSFA 4GCPA 3AA0B 2JMMA 2ES9A 2Y7SA 4FZMA 2ERVA 3SY7A 1OPFA 3AA7B 1IZNB 2LHFA 1Q9FA 2QTKA 4D65A 4QQ1A 2O4VA 3UPGA 3HWBA 4O3YA 5G26A 2Q0TA 2PFXA 1ZHYA 3JTYA 4GF4A 4RJWA 2J1NA 1Q9GA 4FESA 5DL8A 1MPFA 4FSPA 4C69X 2PRNA 1G90A 5DL7A 1LW1A 2IJCA 2XE1A 2AF7A 4FOZA 3WI5A 4G75A 3HOLA 3POUA 1GFPA 4JCHA 5DL6A 3VE1A 4AKRA 3NSGA 1HXXA 2KZ7A 2KXPA 1QJPA 1ME5A 3C5OA 4E1SA 2N2MA 2Y0LA 4KRAA 3PORA 2J4UP 5D5DA 2XTQA 4LSIA 2KDYA 4U9CA 3V8UA 8PRNA 3EMNX 1BH3A 1GFQA 3SZVA 2XE3A 4AFKA 3LK42 3RBHA 4D64A 4Z3TA 1ZHTA 5ADXK 2OYOA 2KC0A 2MHLA 4GCSA 2Y2XA 3PQSA 2PRRA 2N2LA 3VZTX 5T5FA 2M06A 4AKMA 2M07A 3FYXA 4D5UA 3K19A 3LK3B 3BEYA 2YPVA 2CWQA 1GFOA 2PORA 3SYBA 1P4TA 1ZHXA 1E54A 2MNHA 4XNLA 4AYDC 1IZNA 1QJ9A 2GE4A 4E1TA 2XTRA 1VKEA 2X27X 2JN8A 4LSHA 4FRTA 3AAAA 1PHOA 3VZUX 3QRCA 4AKRB 3AA0A 2FGQX 3DA4A 1QJ8A 4G76A 1KNCA 4LSEA 5FVNA 5PRNA 3POQA 1GFMA 3SY9A 2XE5A 3VY8X 1BXWA 4FUVA 2QEUA 4O4XA 5GV0A 3VZWX 3G7GA 4N59A 5ADXL 2GMYA 3LVYA 2Y0KA 3GP6A 4AYMC 3AA1A 4O3WA 2YNKA 5JDPA 5DL5A 3D7IA 3HW9A 3AA7A 1ORMA 4XNKA 5IYUA 3KVDD 3T0SA 2ODJA 2F1TA 2K0LA 4RJXA 4N58A 4RLCA 2W81C 4GCQA 1MM5A 5DIPA 2K4TA 3QRAA 3LK2A 2O4DA 1ZHWA 3O0EA 4PUXA 2Y0HA 3AAAB 4FZNA 6PRNA 3A2SX 2ZLDA 4RL9A 1HXTA 2OUWA 3PQUA 2W80C 5AFUL 3VE2A 7PRNA 3LK3A 3UU2A 3AA6B 4BUMX 1MM4A 3SYSA 4B61A 4O4UA 2OMFA 2ZFGA 4FMSA 3POXA 3C1LA 1YS5A 1GU9A 4G9QA 2XG6A 3AA6A 4GHBA 1OSMA 4KR4A 5EE2A 4FRXA 5DIKA 4FZLA 2XE2A 4O3ZA 3WI4A 4O3XB 4KR8A 2XMXA 4O49A 3TZGA 4AUIA 2FGRA 1GFNA 4FSOA 4AYNA 3T20A 1P8CA 3LK2B 3VY9X 3AAEB 1H6S1 3AAEA 3PRNA 3DA3A 1PRNA 3UAQA 4F4BA 1THQA 4FT6A 1ZHZA 2KZ7B 3HOEA 2F1VA 3AA1B 4AYEC 4JFBA 5AFUK 4AZLA 1HXUA 1BT9A 3LK41
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AA0 A;  3AA6 B;  2KXP B;  3AA6 A;  3AA0 B;  5ADX L;  3LK4 2;  5AFU L;  5ADX K;  3AA1 A;  1IZN B;  3AA7 B;  3AA7 A;  3LK2 B;  3AAE B;  3AAE A;  3LK3 B;  3LK2 A;  3AAA B;  2KZ7 B;  1IZN A;  3AA1 B;  5AFU K;  4AKR A;  3AAA A;  4AKR B;  2KZ7 A;  2KXP A;  3LK4 1;  3LK3 A; 
#chains in the Genus database with same CATH topology
 4IL6 O;  2LFU A;  3SZD A;  4AYI D;  2KXP B;  4RLB A;  5TIS O;  4LSF A;  3T24 A;  4GCP A;  5B5E O;  3AA0 B;  2JMM A;  2JQY A;  2ES9 A;  2Y7S A;  4FZM A;  2ERV A;  3SY7 A;  1OPF A;  4K3C A;  3A0B O;  1IZN B;  3AA7 B;  2R4L A;  2LHF A;  1Q9F A;  2QTK A;  4D65 A;  4PJ0 O;  4QQ1 A;  2O4V A;  3UPG A;  3HWB A;  4O3Y A;  5G26 A;  2Q0T A;  2PFX A;  1ZHY A;  3JTY A;  3PF1 A;  2R4O A;  3NJT A;  4GF4 A;  4RJW A;  5G38 A;  2J1N A;  1Q9G A;  4FES A;  5DL8 A;  1MPF A;  5KAF O;  4FSP A;  4C69 X;  2PRN A;  3KZI O;  4C4V A;  1G90 A;  2WJR A;  5DL7 A;  1LW1 A;  2IJC A;  2XE1 A;  2AF7 A;  4FOZ A;  3WI5 A;  4G75 A;  3HOL A;  3POU A;  1GFP A;  4JCH A;  4PR7 A;  5DL6 A;  3VE1 A;  4AKR A;  3A0H O;  3NSG A;  3BRY A;  1HXX A;  2KZ7 A;  2KXP A;  1QJP A;  1ME5 A;  3BRZ A;  3PGR A;  3C5O A;  5E79 O;  4E1S A;  2N2M A;  2Y0L A;  4N75 A;  3PGU A;  4KRA A;  2WVP A;  3POR A;  5D5D A;  2J4U P;  2XTQ A;  4LSI A;  2KDY A;  4U9C A;  5GTI O;  3V8U A;  3EMN X;  1BH3 A;  1GFQ A;  3SZV A;  2XE3 A;  4AFK A;  3LK4 2;  3RBH A;  4D64 A;  8PRN A;  4Z3T A;  1ZHT A;  5ADX K;  5B66 O;  2OYO A;  2KC0 A;  2MHL A;  4C00 A;  4GCS A;  2Y2X A;  2WJQ A;  3PQS A;  2PRR A;  2N2L A;  3DZM A;  3VZT X;  3PGS A;  5T5F A;  2M06 A;  4AKM A;  5H2F O;  2M07 A;  2R4P A;  3FYX A;  3K19 A;  4D5U A;  3LK3 B;  3BEY A;  3WU2 O;  2YPV A;  2CWQ A;  1GFO A;  2POR A;  3SYB A;  1P4T A;  1ZHX A;  1E54 A;  2IWV A;  2MNH A;  4FQE A;  4XNL A;  4AYD C;  1IZN A;  1QJ9 A;  2GE4 A;  4E1T A;  2XTR A;  1VKE A;  2X27 X;  2JN8 A;  3DWO X;  4LSH A;  4FRT A;  3AAA A;  1PHO A;  5G39 A;  3VZU X;  4C4V B;  2IWW A;  3QRC A;  4AKR B;  2F1C X;  3AA0 A;  2FGQ X;  3DA4 A;  1QJ8 A;  4G76 A;  1KNC A;  4LSE A;  5FVN A;  5PRN A;  3POQ A;  1GFM A;  3SY9 A;  2XE5 A;  3VY8 X;  1BXW A;  1S5L O;  4FUV A;  2QEU A;  3BS0 A;  4K3B A;  4O4X A;  3VZW X;  3G7G A;  4N59 A;  5GV0 A;  5ADX L;  2GMY A;  3LVY A;  4CTD A;  2Y0K A;  3GP6 A;  4AYM C;  3AA1 A;  4O3W A;  2YNK A;  5JDP A;  5DL5 A;  3D7I A;  3HW9 A;  3AA7 A;  1ORM A;  1T16 A;  3DWN A;  4XNK A;  4UB6 O;  3KVD D;  3T0S A;  2ODJ A;  5IYU A;  2F1T A;  2K0L A;  2R4N A;  4RJX A;  4N58 A;  4RLC A;  2W81 C;  4GCQ A;  3JCU O;  1MM5 A;  5DIP A;  2K4T A;  3QRA A;  3LK2 A;  2O4D A;  1ZHW A;  3O0E A;  4PUX A;  2Y0H A;  3AAA B;  4FZN A;  6PRN A;  3A2S X;  2ZLD A;  4RL9 A;  1HXT A;  2OUW A;  3PQU A;  2W80 C;  5AFU L;  3VE2 A;  7PRN A;  3LK3 A;  4UB8 O;  3UU2 A;  3AA6 B;  4BUM X;  1MM4 A;  3SYS A;  4B61 A;  1T1L A;  2OMF A;  2R89 A;  2ZFG A;  4FMS A;  3POX A;  3C1L A;  1YS5 A;  4N74 A;  1GU9 A;  4G9Q A;  2XG6 A;  3AA6 A;  4GHB A;  1OSM A;  2R88 A;  4KR4 A;  4FRX A;  5DIK A;  4FZL A;  2XE2 A;  5EE2 A;  5KAI O;  4O3Z A;  3WI4 A;  2AXT O;  5G3A A;  4O3X B;  4KR8 A;  2XMX A;  4O49 A;  3TZG A;  4AUI A;  2FGR A;  1GFN A;  4FSO A;  4AYN A;  3T20 A;  1P8C A;  3LK2 B;  3VY9 X;  2R8A A;  3AAE B;  1H6S 1;  3AAE A;  3PRN A;  3DA3 A;  1PRN A;  3UAQ A;  4F4B A;  1THQ A;  4FT6 A;  1ZHZ A;  2KZ7 B;  3HOE A;  2F1V A;  3AA1 B;  2X9K A;  4O4U A;  4AYE C;  4JFB A;  5GTH O;  5AFU K;  4AZL A;  1HXU A;  1BT9 A;  3LK4 1; 
#chains in the Genus database with same CATH homology
 2LFU A;  3SZD A;  4AYI D;  2KXP B;  4RLB A;  3T24 A;  4LSF A;  4GCP A;  3AA0 B;  2JMM A;  2ES9 A;  2Y7S A;  4FZM A;  2ERV A;  3SY7 A;  1OPF A;  3AA7 B;  1IZN B;  2LHF A;  1Q9F A;  2QTK A;  4D65 A;  4QQ1 A;  2O4V A;  3UPG A;  3HWB A;  4O3Y A;  5G26 A;  2Q0T A;  2PFX A;  1ZHY A;  3JTY A;  4GF4 A;  4RJW A;  2J1N A;  1Q9G A;  4FES A;  5DL8 A;  1MPF A;  4FSP A;  4C69 X;  2PRN A;  1G90 A;  5DL7 A;  1LW1 A;  2IJC A;  2XE1 A;  2AF7 A;  4FOZ A;  3WI5 A;  4G75 A;  3HOL A;  3POU A;  1GFP A;  4JCH A;  5DL6 A;  3VE1 A;  4AKR A;  3NSG A;  1HXX A;  2KZ7 A;  2KXP A;  1QJP A;  1ME5 A;  3C5O A;  4E1S A;  2N2M A;  2Y0L A;  4KRA A;  3POR A;  2J4U P;  5D5D A;  2XTQ A;  4LSI A;  2KDY A;  4U9C A;  3V8U A;  8PRN A;  3EMN X;  1BH3 A;  1GFQ A;  3SZV A;  2XE3 A;  4AFK A;  3LK4 2;  3RBH A;  4D64 A;  4Z3T A;  1ZHT A;  5ADX K;  2OYO A;  2KC0 A;  2MHL A;  4GCS A;  2Y2X A;  3PQS A;  2PRR A;  2N2L A;  3VZT X;  5T5F A;  2M06 A;  4AKM A;  2M07 A;  3FYX A;  4D5U A;  3K19 A;  3LK3 B;  3BEY A;  2YPV A;  2CWQ A;  1GFO A;  2POR A;  3SYB A;  1P4T A;  1ZHX A;  1E54 A;  2MNH A;  4XNL A;  4AYD C;  1IZN A;  1QJ9 A;  2GE4 A;  4E1T A;  2XTR A;  1VKE A;  2X27 X;  2JN8 A;  4LSH A;  4FRT A;  3AAA A;  1PHO A;  3VZU X;  3QRC A;  4AKR B;  3AA0 A;  2FGQ X;  3DA4 A;  1QJ8 A;  4G76 A;  1KNC A;  4LSE A;  5FVN A;  5PRN A;  3POQ A;  1GFM A;  3SY9 A;  2XE5 A;  3VY8 X;  1BXW A;  4FUV A;  2QEU A;  4O4X A;  5GV0 A;  3VZW X;  3G7G A;  4N59 A;  5ADX L;  2GMY A;  3LVY A;  2Y0K A;  3GP6 A;  4AYM C;  3AA1 A;  4O3W A;  2YNK A;  5JDP A;  5DL5 A;  3D7I A;  3HW9 A;  3AA7 A;  1ORM A;  4XNK A;  5IYU A;  3KVD D;  3T0S A;  2ODJ A;  2F1T A;  2K0L A;  4RJX A;  4N58 A;  4RLC A;  2W81 C;  4GCQ A;  1MM5 A;  5DIP A;  2K4T A;  3QRA A;  3LK2 A;  2O4D A;  1ZHW A;  3O0E A;  4PUX A;  2Y0H A;  3AAA B;  4FZN A;  6PRN A;  3A2S X;  2ZLD A;  4RL9 A;  1HXT A;  2OUW A;  3PQU A;  2W80 C;  5AFU L;  3VE2 A;  7PRN A;  3LK3 A;  3UU2 A;  3AA6 B;  4BUM X;  1MM4 A;  3SYS A;  4B61 A;  4O4U A;  2OMF A;  2ZFG A;  4FMS A;  3POX A;  3C1L A;  1YS5 A;  1GU9 A;  4G9Q A;  2XG6 A;  3AA6 A;  4GHB A;  1OSM A;  4KR4 A;  5EE2 A;  4FRX A;  5DIK A;  4FZL A;  2XE2 A;  4O3Z A;  3WI4 A;  4O3X B;  4KR8 A;  2XMX A;  4O49 A;  3TZG A;  4AUI A;  2FGR A;  1GFN A;  4FSO A;  4AYN A;  3T20 A;  1P8C A;  3LK2 B;  3VY9 X;  3AAE B;  1H6S 1;  3AAE A;  3PRN A;  3DA3 A;  1PRN A;  3UAQ A;  4F4B A;  1THQ A;  4FT6 A;  1ZHZ A;  2KZ7 B;  3HOE A;  2F1V A;  3AA1 B;  4AYE C;  4JFB A;  5AFU K;  4AZL A;  1HXU A;  1BT9 A;  3LK4 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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