3LLLA

Crystal structure of mouse pacsin2 f-bar domain
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
287
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCGDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLEVKASLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKTIYRELEQSIKAADAVEDLRWFRANHGPGMAMNWPQFE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title A hinge in the distal end of the PACSIN 2 F-BAR domain may contribute to membrane-curvature sensing.
pubmed doi rcsb
source organism Mus musculus
molecule tags Endocytosis
total genus 105
structure length 287
sequence length 287
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3lllA01
3HAJA 1X04A 2D1LA 4ATMA 2RAJA 2EFLA 3ACOA 4AKVA 1I49A 1URUA 2V0OA 3QE6A 5C5BA 3G9GA 3ABHA 3Q84A 3QNIA 3QWEA 2YKTA 4H8SA 3HAHA 4AVMA 2Q12A 4DCNC 4DYLA 3HAIA 2Z0OA 2Z0NA 3M3WA 2RAKA 2C08A 2X3XA 1ZWWA 2ELBA 4NSWA 3I2WA 3LLLA 3OK8A 4BNEA 3PLTA 4NQIA 1Y2OA 2Z0VA 3Q0KA 2X3WA 2Q13A 2EFKA 3SOGA 2D4CA 2RAIA 2FICA 4FZSA 1I4TA 1WDZA 3CAZA 3DYTA 5C5BB 1I4LA 3SYVA 4WPCA 4WPEA 4I1QA 1I4DA 2X3VA 1X03A
chains in the Genus database with same CATH superfamily
2F1AA 4AKVA 4E3CA 4AZHA 2WYHA 4JL9A 4DCNC 2Q12A 3CKDA 4AZGA 4KIKA 2OBLA 1TQVA 2WYIA 4AZBA 2RAKA 4EZUA 4H6IA 1OA1A 2X5CA 4R5IA 3DX0A 3DPOA 3RV1A 2PY6A 4FZPA 3CV5A 3ABHA 3B51X 1R33A 1GN9A 3DDFA 4AZ7A 1GNLA 3D50A 2OO2A 4UDYX 1UPXA 4JWEA 3CAZA 4HY9A 3UITA 4EZSA 3OHXM 3O3NB 3QWEA 4AZIA 4DYLA 5FIGA 4EZPA 5FLEX 4M0MA 1TQWA 1GNTA 1QWNA 3BUQA 4FZSA 4AZ6A 3SYVA 1X04A 2YI8A 2V0OA 1HXKA 3D51A 4EZQA 2EWFA 2GAFD 4R5KA 4UDXX 4R5JA 3KAVA 2RT6A 3BVTA 4ATMA 4IW0A 4F01A 3T48A 4EZRA 4E81A 5C5BA 4IM2A 4D8JA 2F7QA 4H6HA 3C7NA 3EJTA 2OZNB 3CZSA 2YIAA 3EJQA 1I4LA 3LMFA 1SU7A 1OAOA 1DKZA 2N3KA 3LLLA 3RPMA 3DX4A 4IWPA 1I49A 1U00A 4H8SA 3VKHA 2NCZA 3EJUA 3VEAA 2X3WA 3D2FA 2F18A 4R5LA 2YLLA 4WPCA 1DKYA 1YWMA 3DX1A 4AZ5A 3VEBA 1HTYA 4EZOA 1PS3A 1SU8A 3M3WA 1ZYLA 3EJPA 4NSWA 3OK8A 2OBMA 2Z8YA 1E9VA 2YL6A 4EZWA 3DPQA 3BUIA 3ZEDA 1R5EA 2F7RA 3I2WA 4BNEA 2Q13A 3BVWA 2RAIA 4IWOA 5KBPA 2FYVA 2YL5A 4R5GA 3I04A 1X03A 4AZCB 2YIVX 5TKYA 3DPPA 3D4ZA 3LVTA 4HR1B 4JWCA 2MI7A 2Z0OA 3DX3A 4IWQA 3D4YA 3BUPA 1WDZA 2WINM 3D52A 2OW7A 2EFLA 1QX1A 2F1BA 3GI7A 3B52X 2YL8A 1DKXA 3FD9A 2C08A 4JWDA 3BVVA 2PMRA 2QFFA 2ZXQA 1LQ7A 2JNSA 4JNFA 4NPHA 3ACOA 4EZTA 3KDRA 3I39X 2YIBA 2GF4A 4FZOA 4IM3A 2Z0NA 3DDGA 2X3XA 2ELBA 2KHOA 2YL9A 3QNJA 3ER8C 2EFKA 4EZVA 2YLAA 1TQUA 1SUFA 2YI9A 3CVRA 1O7DB 3T46A 5E84A 4EZYA 4HYBA 2ND1A 3G9GA 3Q84A 3QNIA 2QXLA 4AVMA 4IM0A 1E2UA 4EZXA 3O3MB 1Y2OA 3EJSA 1O7DC 1QWUA 2EX3B 4KIKB 3DX2A 2RAJA 3CZNA 3EJRA 3BVUA 1URUA 2O0I1 3RV0A 3HAHA 4EZZA 3BLBA 1SU6A 4AZCA 3QA8A 3BUDA 3Q0KA 4HR1A 2QKWA 1I4TA 1E1DA 3ERCC 2ND0A 1W9MA 2F7OA 2D1LA 3OWGA 3B53X 4JNEA 1HWWA 3F7WA 4JN4A 2OW6A 4EZNA 1ZWWA 4B9QA 4G6QA 3T4AG 2Z0VA 3O3OB 2FICA 3ER9B 4WPEA 2X3VA 3KAWA 2ALWA 4JWIA 1OA0A 3BUBA 1MJGA 3I01A 1TQTA 3A98A 2LXYA 2LM0A 3L3OM 3PLTA 4NQIA 3SOGA 2D4CA 1R34A 3DYTA 3T49A 4I1QA 1I4DA 3HAJA 3L3PA 4JLCA 3QE6A 2YKTA 2F7PA 2JNKA 4PO2A 2GA9D 3T47A 3BVXA 5C5BB 3D2EA 4F00A 1TQSA 4FM3A 1JQKA 3HAIA
chains in the Genus database with same CATH topology
3HAJA 1X04A 2D1LA 4ATMA 2RAJA 2EFLA 3ACOA 4AKVA 1I49A 1URUA 2V0OA 3QE6A 5C5BA 3G9GA 3ABHA 3Q84A 3QNIA 3QWEA 2YKTA 4H8SA 3HAHA 4AVMA 2Q12A 4DCNC 4DYLA 3HAIA 2Z0OA 2Z0NA 3M3WA 2RAKA 2C08A 2X3XA 1ZWWA 2ELBA 4NSWA 3I2WA 3LLLA 3OK8A 4BNEA 3PLTA 4NQIA 1Y2OA 2Z0VA 3Q0KA 2X3WA 2Q13A 2EFKA 3SOGA 2D4CA 2RAIA 2FICA 4FZSA 1I4TA 1WDZA 3CAZA 3DYTA 5C5BB 1I4LA 3SYVA 4WPCA 4WPEA 4I1QA 1I4DA 2X3VA 1X03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HAJ A;  1X04 A;  2D1L A;  4ATM A;  2RAJ A;  2EFL A;  3ACO A;  4AKV A;  1I49 A;  1URU A;  2V0O A;  3QE6 A;  5C5B A;  3G9G A;  3ABH A;  3Q84 A;  3QNI A;  3QWE A;  2YKT A;  4H8S A;  3HAH A;  4AVM A;  2Q12 A;  4DCN C;  4DYL A;  3HAI A;  2Z0O A;  2Z0N A;  3M3W A;  2RAK A;  2C08 A;  2X3X A;  1ZWW A;  2ELB A;  4NSW A;  3I2W A;  3LLL A;  3OK8 A;  4BNE A;  3PLT A;  4NQI A;  1Y2O A;  2Z0V A;  3Q0K A;  2X3W A;  2Q13 A;  2EFK A;  3SOG A;  2D4C A;  2RAI A;  2FIC A;  4FZS A;  1I4T A;  1WDZ A;  3CAZ A;  3DYT A;  5C5B B;  1I4L A;  3SYV A;  4WPC A;  4WPE A;  4I1Q A;  1I4D A;  2X3V A;  1X03 A; 
#chains in the Genus database with same CATH topology
 2F1A A;  4AKV A;  4E3C A;  4AZH A;  2WYH A;  4JL9 A;  4DCN C;  2Q12 A;  3CKD A;  4AZG A;  4KIK A;  2OBL A;  1TQV A;  2WYI A;  4AZB A;  2RAK A;  4EZU A;  4H6I A;  1OA1 A;  2X5C A;  4R5I A;  3DX0 A;  3DPO A;  3RV1 A;  2PY6 A;  4FZP A;  3CV5 A;  3ABH A;  3B51 X;  1R33 A;  1GN9 A;  3DDF A;  4AZ7 A;  1GNL A;  3D50 A;  2OO2 A;  4UDY X;  1UPX A;  4JWE A;  3CAZ A;  4HY9 A;  3UIT A;  4EZS A;  3OHX M;  3O3N B;  3QWE A;  4AZI A;  4DYL A;  5FIG A;  4EZP A;  5FLE X;  4M0M A;  1TQW A;  1GNT A;  1QWN A;  3BUQ A;  4FZS A;  4AZ6 A;  3SYV A;  1X04 A;  2YI8 A;  2V0O A;  1HXK A;  3D51 A;  4EZQ A;  2EWF A;  2GAF D;  4R5K A;  4UDX X;  4R5J A;  3KAV A;  2RT6 A;  3BVT A;  4ATM A;  4IW0 A;  4F01 A;  3T48 A;  4EZR A;  4E81 A;  5C5B A;  4IM2 A;  4D8J A;  2F7Q A;  4H6H A;  3C7N A;  3EJT A;  2OZN B;  3CZS A;  2YIA A;  3EJQ A;  1I4L A;  3LMF A;  1SU7 A;  1OAO A;  1DKZ A;  2N3K A;  3LLL A;  3RPM A;  3DX4 A;  4IWP A;  1I49 A;  1U00 A;  4H8S A;  3VKH A;  2NCZ A;  3EJU A;  3VEA A;  2X3W A;  3D2F A;  2F18 A;  4R5L A;  2YLL A;  4WPC A;  1DKY A;  1YWM A;  3DX1 A;  4AZ5 A;  3VEB A;  1HTY A;  4EZO A;  1PS3 A;  1SU8 A;  3M3W A;  1ZYL A;  3EJP A;  4NSW A;  3OK8 A;  2OBM A;  2Z8Y A;  1E9V A;  2YL6 A;  4EZW A;  3DPQ A;  3BUI A;  3ZED A;  1R5E A;  2F7R A;  3I2W A;  4BNE A;  2Q13 A;  3BVW A;  2RAI A;  4IWO A;  5KBP A;  2FYV A;  2YL5 A;  4R5G A;  3I04 A;  1X03 A;  4AZC B;  2YIV X;  5TKY A;  3DPP A;  3D4Z A;  3LVT A;  4HR1 B;  4JWC A;  2MI7 A;  2Z0O A;  3DX3 A;  4IWQ A;  3D4Y A;  3BUP A;  1WDZ A;  2WIN M;  3D52 A;  2OW7 A;  2EFL A;  1QX1 A;  2F1B A;  3GI7 A;  3B52 X;  2YL8 A;  1DKX A;  3FD9 A;  2C08 A;  4JWD A;  3BVV A;  2PMR A;  2QFF A;  2ZXQ A;  1LQ7 A;  2JNS A;  4JNF A;  4NPH A;  3ACO A;  4EZT A;  3KDR A;  3I39 X;  2YIB A;  2GF4 A;  4FZO A;  4IM3 A;  2Z0N A;  3DDG A;  2X3X A;  2ELB A;  2KHO A;  2YL9 A;  3QNJ A;  3ER8 C;  2EFK A;  4EZV A;  2YLA A;  1TQU A;  1SUF A;  2YI9 A;  3CVR A;  1O7D B;  3T46 A;  5E84 A;  4EZY A;  4HYB A;  2ND1 A;  3G9G A;  3Q84 A;  3QNI A;  2QXL A;  4AVM A;  4IM0 A;  1E2U A;  4EZX A;  3O3M B;  1Y2O A;  3EJS A;  1O7D C;  1QWU A;  2EX3 B;  4KIK B;  3DX2 A;  2RAJ A;  3CZN A;  3EJR A;  3BVU A;  1URU A;  2O0I 1;  3RV0 A;  3HAH A;  4EZZ A;  3BLB A;  1SU6 A;  4AZC A;  3QA8 A;  3BUD A;  3Q0K A;  4HR1 A;  2QKW A;  1I4T A;  1E1D A;  3ERC C;  2ND0 A;  1W9M A;  2F7O A;  2D1L A;  3OWG A;  3B53 X;  4JNE A;  1HWW A;  3F7W A;  4JN4 A;  2OW6 A;  4EZN A;  1ZWW A;  4B9Q A;  4G6Q A;  3T4A G;  2Z0V A;  3O3O B;  2FIC A;  3ER9 B;  4WPE A;  2X3V A;  3KAW A;  2ALW A;  4JWI A;  1OA0 A;  3BUB A;  1MJG A;  3I01 A;  1TQT A;  3A98 A;  2LXY A;  2LM0 A;  3L3O M;  3PLT A;  4NQI A;  3SOG A;  2D4C A;  1R34 A;  3DYT A;  3T49 A;  4I1Q A;  1I4D A;  3HAJ A;  3L3P A;  4JLC A;  3QE6 A;  2YKT A;  2F7P A;  2JNK A;  4PO2 A;  2GA9 D;  3T47 A;  3BVX A;  5C5B B;  3D2E A;  4F00 A;  1TQS A;  4FM3 A;  1JQK A;  3HAI A; 
#chains in the Genus database with same CATH homology
 3HAJ A;  1X04 A;  2D1L A;  4ATM A;  2RAJ A;  2EFL A;  3ACO A;  4AKV A;  1I49 A;  1URU A;  2V0O A;  3QE6 A;  5C5B A;  3G9G A;  3ABH A;  3Q84 A;  3QNI A;  3QWE A;  2YKT A;  4H8S A;  3HAH A;  4AVM A;  2Q12 A;  4DCN C;  4DYL A;  3HAI A;  2Z0O A;  2Z0N A;  3M3W A;  2RAK A;  2C08 A;  2X3X A;  1ZWW A;  2ELB A;  4NSW A;  3I2W A;  3LLL A;  3OK8 A;  4BNE A;  3PLT A;  4NQI A;  1Y2O A;  2Z0V A;  3Q0K A;  2X3W A;  2Q13 A;  2EFK A;  3SOG A;  2D4C A;  2RAI A;  2FIC A;  4FZS A;  1I4T A;  1WDZ A;  3CAZ A;  3DYT A;  5C5B B;  1I4L A;  3SYV A;  4WPC A;  4WPE A;  4I1Q A;  1I4D A;  2X3V A;  1X03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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