3LPQA

Human mitoneet with 2fe-2s coordinating ligand his 87 replaced with cys
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
75
structure length
75
Chain Sequence
RFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGACTKHNEETGDNVGPLIIKKKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords CDGSH iron sulfur domain-containing protein 1
total genus 12
structure length 75
sequence length 75
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09360 zf-CDGSH Iron-binding zinc finger CDGSH type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.5.90 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L9; domain 1 Ribosomal Protein L9; domain 1 3lpqA00
3REEA 2QH7A 4EZFA 3S2QA 4OOAA 4F1EA 3TBNA 4F2CA 2QD0A 3FNVA 2R13A 4OO7A 3LPQA 3S2RA 3TBOA 4F28A 3EW0A
chains in the Genus database with same CATH superfamily
4EZFA 3S2QA 4FSDA 2X49A 3FNDA 4UY8H 2QD0A 3ANWA 2HVFA 3J7ZH 5EG5A 2E9XD 1CQUA 2Q9QA 2EHOC 5GHRB 3CO4A 4F1EA 4FR0A 4FS8A 2LSMA 3FNVA 2R13A 3LPQA 5GHSC 2QH7A 2OUTA 4OOAA 4RSRA 2HJQA 3TBNA 3S2RA 3TBOA 4F28A 3EW0A 3REEA 4F2CA 4KW7A 1DIVA 4OO7A 2E9XB 2HBAA 2X4AA 2Q9QB 2HBBA
chains in the Genus database with same CATH topology
4EZFA 3S2QA 4FSDA 2X49A 2QD0A 3ANWA 5EG5A 2E9XD 2Q9QA 2EHOC 5GHRB 4F1EA 4FR0A 4FS8A 2LSMA 3FNVA 2R13A 3LPQA 5GHSC 2QH7A 2OUTA 4OOAA 4RSRA 3TBNA 3S2RA 3TBOA 4F28A 3REEA 4F2CA 4KW7A 4OO7A 2E9XB 3EW0A 2X4AA 2Q9QB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3REE A;  2QH7 A;  4EZF A;  3S2Q A;  4OOA A;  4F1E A;  3TBN A;  4F2C A;  2QD0 A;  3FNV A;  2R13 A;  4OO7 A;  3LPQ A;  3S2R A;  3TBO A;  4F28 A;  3EW0 A; 
#chains in the Genus database with same CATH topology
 4EZF A;  3S2Q A;  4FSD A;  2X49 A;  3FND A;  4UY8 H;  2QD0 A;  3ANW A;  2HVF A;  3J7Z H;  5EG5 A;  2E9X D;  1CQU A;  2Q9Q A;  2EHO C;  5GHR B;  3CO4 A;  4F1E A;  4FR0 A;  4FS8 A;  2LSM A;  3FNV A;  2R13 A;  3LPQ A;  5GHS C;  2QH7 A;  2OUT A;  4OOA A;  4RSR A;  2HJQ A;  3TBN A;  3S2R A;  3TBO A;  4F28 A;  3EW0 A;  3REE A;  4F2C A;  4KW7 A;  1DIV A;  4OO7 A;  2E9X B;  2HBA A;  2X4A A;  2Q9Q B;  2HBB A; 
#chains in the Genus database with same CATH homology
 4EZF A;  3S2Q A;  4FSD A;  2X49 A;  2QD0 A;  3ANW A;  5EG5 A;  2E9X D;  2Q9Q A;  2EHO C;  5GHR B;  4F1E A;  4FR0 A;  4FS8 A;  2LSM A;  3FNV A;  2R13 A;  3LPQ A;  5GHS C;  2QH7 A;  2OUT A;  4OOA A;  4RSR A;  3TBN A;  3S2R A;  3TBO A;  4F28 A;  3REE A;  4F2C A;  4KW7 A;  4OO7 A;  2E9X B;  3EW0 A;  2X4A A;  2Q9Q B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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