3LRIA

Solution structure and backbone dynamics of long-[arg(3)]insulin-like growth factor-i
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
83
structure length
83
Chain Sequence
MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRACQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords PROTEIN (INSULIN-LIKE GROWTH FACTOR I)
publication title Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I
pubmed doi rcsb
source organism Homo sapiens
total genus 7
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 1999-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 3lriA00
1BQTA 1GZYB 2KJIA 2L29B 1TGRA 4XSSB 1H59A 1H02B 1EFEA 1IMXA 1IGLA 2LWZA 2GF1A 5L3MA 2DSQC 5L3LA 3GF1A 1GZZB 3LRIA 1PMXA 3KR3D 1WQJI 6INSE 2KQPA 5L3NA 1SJUA 1ZEIA 1GZRB 2DSPI 2DSRI 2JZQA 1B9GA
chains in the Genus database with same CATH superfamily
1BQTA 1GZYB 2KJIA 2L29B 1TGRA 4XSSB 1H59A 2L14B 1H02B 1EFEA 1IMXA 1IGLA 2LWZA 2GF1A 5L3MA 2DSQC 5L3LA 3GF1A 1GZZB 3LRIA 3F2BA 3F2CA 1PMXA 3KR3D 1WQJI 6INSE 2KQPA 5L3NA 1SJUA 1ZEIA 1GZRB 2DSPI 2DSRI 3F2DA 2JZQA 1B9GA
chains in the Genus database with same CATH topology
1BQTA 1GZYB 2KJIA 2L29B 1TGRA 4XSSB 1H59A 1H02B 1EFEA 1IMXA 1IGLA 2LWZA 2GF1A 5L3MA 2DSQC 5L3LA 3GF1A 1GZZB 3LRIA 1PMXA 3KR3D 1WQJI 6INSE 2KQPA 5L3NA 1SJUA 1ZEIA 1GZRB 2DSPI 2DSRI 2JZQA 1B9GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BQT A;  1GZY B;  2KJI A;  2L29 B;  1TGR A;  4XSS B;  1H59 A;  1H02 B;  1EFE A;  1IMX A;  1IGL A;  2LWZ A;  2GF1 A;  5L3M A;  2DSQ C;  5L3L A;  3GF1 A;  1GZZ B;  3LRI A;  1PMX A;  3KR3 D;  1WQJ I;  6INS E;  2KQP A;  5L3N A;  1SJU A;  1ZEI A;  1GZR B;  2DSP I;  2DSR I;  2JZQ A;  1B9G A; 
#chains in the Genus database with same CATH topology
 1BQT A;  1GZY B;  2KJI A;  2L29 B;  1TGR A;  4XSS B;  1H59 A;  2L14 B;  1H02 B;  1EFE A;  1IMX A;  1IGL A;  2LWZ A;  2GF1 A;  5L3M A;  2DSQ C;  5L3L A;  3GF1 A;  1GZZ B;  3LRI A;  3F2B A;  3F2C A;  1PMX A;  3KR3 D;  1WQJ I;  6INS E;  2KQP A;  5L3N A;  1SJU A;  1ZEI A;  1GZR B;  2DSP I;  2DSR I;  3F2D A;  2JZQ A;  1B9G A; 
#chains in the Genus database with same CATH homology
 1BQT A;  1GZY B;  2KJI A;  2L29 B;  1TGR A;  4XSS B;  1H59 A;  1H02 B;  1EFE A;  1IMX A;  1IGL A;  2LWZ A;  2GF1 A;  5L3M A;  2DSQ C;  5L3L A;  3GF1 A;  1GZZ B;  3LRI A;  1PMX A;  3KR3 D;  1WQJ I;  6INS E;  2KQP A;  5L3N A;  1SJU A;  1ZEI A;  1GZR B;  2DSP I;  2DSR I;  2JZQ A;  1B9G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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