3LRRA

Crystal structure of human rig-i ctd bound to a 12 bp au rich 5' ppp dsrna
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 25
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3lrrA00
3LRNA 4A2XA 3NCUA 2RMJA 3ZD6A 3EQTA 3ZD7A 4A2VA 2W4RA 5F9FA 2QFDA 5E3HA 3OG8A 3GA3A 2QFBA 4BPBA 2RQAA 2RQBA 5F98A 4AY2A 5F9HA 2YKGA 3LRRA
chains in the Genus database with same CATH superfamily
2KZNA 4CI2B 3WX2A 4CI3B 3LRNA 4A2XA 3E0MA 3DJMA 3NCUA 2RMJA 2LVLA 3HCGA 5AMHA 4CI1B 1FWQA 3ZD6A 3EQTA 3ZD7A 4A2VA 3EBMA 4V31A 1YZ1A 2W4RA 4V30A 2FU5A 3P3KA 5F9FA 3CEZA 1HXRA 2HR9A 2LOYA 2QFDA 4V2YA 4TZUA 5E3HA 3OG8A 3GA3A 4TZCA 3FACA 2QFBA 3HCIA 3WX1A 4BPBA 2RQAA 2RQBA 2K8DA 5F98A 1H7YA 3E0OA 3MAOA 4TZ4C 1H6QA 3HCHA 4AY2A 2KV1A 5F9HA 3HCJA 3CXKA 2KWBA 1TXJA 1L1DA 4V2ZA 2YKGA 3LRRA
chains in the Genus database with same CATH topology
3LRNA 4A2XA 3DJMA 3NCUA 2RMJA 2LVLA 1FWQA 3ZD6A 3EQTA 3ZD7A 4A2VA 3EBMA 1YZ1A 2W4RA 2FU5A 3P3KA 5F9FA 1HXRA 2HR9A 2LOYA 2QFDA 5E3HA 3OG8A 3GA3A 3FACA 2QFBA 4BPBA 2RQAA 2RQBA 5F98A 1H7YA 1H6QA 4AY2A 5F9HA 2KWBA 1TXJA 2YKGA 3LRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LRN A;  4A2X A;  3NCU A;  2RMJ A;  3ZD6 A;  3EQT A;  3ZD7 A;  4A2V A;  2W4R A;  5F9F A;  2QFD A;  5E3H A;  3OG8 A;  3GA3 A;  2QFB A;  4BPB A;  2RQA A;  2RQB A;  5F98 A;  4AY2 A;  5F9H A;  2YKG A;  3LRR A; 
#chains in the Genus database with same CATH topology
 2KZN A;  4CI2 B;  3WX2 A;  4CI3 B;  3LRN A;  4A2X A;  3E0M A;  3DJM A;  3NCU A;  2RMJ A;  2LVL A;  3HCG A;  5AMH A;  4CI1 B;  1FWQ A;  3ZD6 A;  3EQT A;  3ZD7 A;  4A2V A;  3EBM A;  4V31 A;  1YZ1 A;  2W4R A;  4V30 A;  2FU5 A;  3P3K A;  5F9F A;  3CEZ A;  1HXR A;  2HR9 A;  2LOY A;  2QFD A;  4V2Y A;  4TZU A;  5E3H A;  3OG8 A;  3GA3 A;  4TZC A;  3FAC A;  2QFB A;  3HCI A;  3WX1 A;  4BPB A;  2RQA A;  2RQB A;  2K8D A;  5F98 A;  1H7Y A;  3E0O A;  3MAO A;  4TZ4 C;  1H6Q A;  3HCH A;  4AY2 A;  2KV1 A;  5F9H A;  3HCJ A;  3CXK A;  2KWB A;  1TXJ A;  1L1D A;  4V2Z A;  2YKG A;  3LRR A; 
#chains in the Genus database with same CATH homology
 3LRN A;  4A2X A;  3DJM A;  3NCU A;  2RMJ A;  2LVL A;  1FWQ A;  3ZD6 A;  3EQT A;  3ZD7 A;  4A2V A;  3EBM A;  1YZ1 A;  2W4R A;  2FU5 A;  3P3K A;  5F9F A;  1HXR A;  2HR9 A;  2LOY A;  2QFD A;  5E3H A;  3OG8 A;  3GA3 A;  3FAC A;  2QFB A;  4BPB A;  2RQA A;  2RQB A;  5F98 A;  1H7Y A;  1H6Q A;  4AY2 A;  5F9H A;  2KWB A;  1TXJ A;  2YKG A;  3LRR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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