3LWQB

Structure of h/aca rnp bound to a substrate rna containing 3mu
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
51
structure length
51
Chain Sequence
RIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 5
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwqB00
3MQKB 2HVYC 3LWOB 2AQCA 3LWVB 3LWRB 2EY4E 3LWQB 3HAXC 3HJWB 2RFKB 3HJYB 2AUSB 3LWPB 2APOB
chains in the Genus database with same CATH superfamily
3HOVL 5M3FL 1F4LA 2J9UB 1PFWA 2JA6L 5AI2A 5IYDL 2Z3RB 3LNLA 4AI2A 1SMWA 4ME3A 4POFA 5H1Sc 3JR7A 5DM71 2VUML 3S1RL 4AYBP 2JI1A 3KYYA 4BBSL 4AR3A 2R93L 4A3ML 2WB1P 1R0FA 3HOXL 2XJRA 2XJUA 1H7VA 1RYQA 2JI2A 3H97A 1BFYA 3LWRB 1VZGA 2XJSA 1DX8A 1DVBA 4C3JL 1OWBA 3I4ML 3LWVB 2GMGA 4C3HL 4TVMA 5DM61 3S1QL 2PYAA 3HAXC 4QIWP 2V0FA 4AR6A 2RFKB 3GTQL 2E2HL 2NVYL 1R0GA 3H0GL 2A68D 2BE5D 2RDVA 3J7Y1 3K35A 2MS3A 2A6ED 3WWLA 2XJTA 4A3LL 3M3YL 4BXXL 2AUSB 2ERJA 1B2OA 3FDJA 2YU9L 3LPEB 2CKAA 4AHWA 3NFPI 1PFUA 1SMMA 1S2ZA 2AYJA 1OWCA 3PWFA 4XGHA 1NXGA 1NNQA 3GTGL 1RDGA 3S1NL 3S2DL 5GAEc 3RZOL 3RZTA 4C2M1 1TWFL 1YV1A 6RXNA 1CAAA 1B2JA 3HOYL 4BY7L 1LKMA 4A3KL 5K2ME 4AI1A 1BRFA 4ZN1B 2R92L 2PSMC 1LKPA 4TPUA 2CR8A 1I50L 2O5JD 2JI3A 2XJPA 4C3IL 4YWLA 1QYBA 2NVTL 1I3QL 4X6AL 2NYDA 1RWDA 3RZ6A 2R7ZL 1TWCL 3GTOL 3QQCE 1P7PA 3PO2L 4AHYA 2V3BB 2B63L 4B8CD 5FJ8L 5M5XL 4G6BA 2JA5L 5C4JL 2ZIXA 1R0JA 3S14L 1WJVA 1Y1VL 5IYBL 3HJWB 1IU5A 2Y0SP 1ODHA 4AI0A 4A3IL 2CKCA 1Z92B 1QCVA 1JYBA 2APOB 3MSUA 3LWOB 5IP7L 1PFYA 4U671 3PKJA 3KYVA 1K83L 2PVXA 3HOZL 5M5WL 3HOUL 1S24A 5IYCL 3PKIA 5MGNA 4LHLA 2PVEA 1RB9A 2LCQA 2M6OA 2V0EA 5JVG1 4BY1L 2JA8L 4AR4A 5C44L 1IROA 5C4XL 4Y7NL 2A6HD 8RXNA 2E2IL 1C09A 2PMZP 4AR5A 2C6AA 3H9CA 4A3FL 4JAFA 1CADA 4A93L 2VL6A 3VPBE 3PL5A 3MPSA 4A3BL 5JVH1 3PZAA 1WCML 3P2AA 3KYUA 1TWHL 5MFZA 5GAGc 3RZDL 2WAQP 1PZXA 4V196 1PFVA 3GTML 1T9OA 4A3JL 3B0AB 5M3ML 2L0ZA 3KYWA 1S30A 1NXEA 2E2JL 1YK4A 5M5YL 2NVXL 4E6YA 2NVQL 1QQTA 4BBRL 2HVYC 3H99A 3GTPL 3H9BA 1BE7A 5MF6A 4ZN3B 1YK5A 2KKDA 2QL0A 1YUZA 4AI3A 3S2HL 1R9TL 1ZRPA 1RYTA 1LTLA 3QVDA 3HJYB 2AQCA 1BQ8A 2M4VA 1TWAL 2C6BA 3HOWL 2B5ID 3PO3L 1IRNA 1VZHA 4POGA 2K2DA 4LHNA 1E8JA 5GADc 4AHXA 3H3VM 2DSXA 1VCXA 4RXNA 3GTJL 5FLML 2XJVA 3WWNB 2KN9A 5GAHc 2Z3QB 3FKIL 2HR5A 1YUXA 2A69D 5MLC3 3S1ML 2XJQA 1T9PA 5RXNA 5AI3A 3GTLL 4A3DL 5MFPA 3CQZL 3PIP1 3I4NL 2JA7L 3MQKB 5C3EL 2EY4E 4A3CL 1BQ9A 3J7Z1 1B71A 1RDVA 4A3GL 3HKZP 4UY81 1B13A 3P8BA 3PIO1 4JADA 3GTKL 4WFN1 5EINC 2H12A 2M4YA 3LWQB 2M6PA 1LKOA 3K7AL 4JAEA 2PPTA 1I6HL 4XXBB 7RXNA 3M4OL 4Y52L 4JAGA 4K9FA 1FHHA 3S17L 1SMUA 5AN9H 3B08B 1TWGL 3ZG6A 5IY0A 4A3EL 4GS7D 3KYXA 3A44A 1FHMA 1VZIA 5EIOC 3S16L 3LWPB 5IP9L 1IU6A 4YWMA 3IU3I 1R0HA 4AHZA 1IW7D 1SFOL 1Y1WL 2ERSA 1R0IA 3RYGA 3S15L 1T9QA 3SS2A
chains in the Genus database with same CATH topology
3MQKB 2HVYC 3LWOB 2AQCA 3LWVB 3LWRB 2EY4E 3LWQB 3HAXC 3HJWB 2RFKB 3HJYB 2AUSB 3LWPB 2APOB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MQK B;  2HVY C;  3LWO B;  2AQC A;  3LWV B;  3LWR B;  2EY4 E;  3LWQ B;  3HAX C;  3HJW B;  2RFK B;  3HJY B;  2AUS B;  3LWP B;  2APO B; 
#chains in the Genus database with same CATH topology
 3HOV L;  5M3F L;  1F4L A;  2J9U B;  1PFW A;  2JA6 L;  5AI2 A;  5IYD L;  2Z3R B;  3LNL A;  4AI2 A;  1SMW A;  4ME3 A;  4POF A;  5H1S c;  3JR7 A;  5DM7 1;  2VUM L;  3S1R L;  4AYB P;  2JI1 A;  3KYY A;  4BBS L;  4AR3 A;  2R93 L;  4A3M L;  2WB1 P;  1R0F A;  3HOX L;  2XJR A;  2XJU A;  1H7V A;  1RYQ A;  2JI2 A;  3H97 A;  1BFY A;  3LWR B;  1VZG A;  2XJS A;  1DX8 A;  1DVB A;  4C3J L;  1OWB A;  3I4M L;  3LWV B;  2GMG A;  4C3H L;  4TVM A;  5DM6 1;  3S1Q L;  2PYA A;  3HAX C;  4QIW P;  2V0F A;  4AR6 A;  2RFK B;  3GTQ L;  2E2H L;  2NVY L;  1R0G A;  3H0G L;  2A68 D;  2BE5 D;  2RDV A;  3J7Y 1;  3K35 A;  2MS3 A;  2A6E D;  3WWL A;  2XJT A;  4A3L L;  3M3Y L;  4BXX L;  2AUS B;  2ERJ A;  1B2O A;  3FDJ A;  2YU9 L;  3LPE B;  2CKA A;  4AHW A;  3NFP I;  1PFU A;  1SMM A;  1S2Z A;  2AYJ A;  1OWC A;  3PWF A;  4XGH A;  1NXG A;  1NNQ A;  3GTG L;  1RDG A;  3S1N L;  3S2D L;  5GAE c;  3RZO L;  3RZT A;  4C2M 1;  1TWF L;  1YV1 A;  6RXN A;  1CAA A;  1B2J A;  3HOY L;  4BY7 L;  1LKM A;  4A3K L;  5K2M E;  4AI1 A;  1BRF A;  4ZN1 B;  2R92 L;  2PSM C;  1LKP A;  4TPU A;  2CR8 A;  1I50 L;  2O5J D;  2JI3 A;  2XJP A;  4C3I L;  4YWL A;  1QYB A;  2NVT L;  1I3Q L;  4X6A L;  2NYD A;  1RWD A;  3RZ6 A;  2R7Z L;  1TWC L;  3GTO L;  3QQC E;  1P7P A;  3PO2 L;  4AHY A;  2V3B B;  2B63 L;  4B8C D;  5FJ8 L;  5M5X L;  4G6B A;  2JA5 L;  5C4J L;  2ZIX A;  1R0J A;  3S14 L;  1WJV A;  1Y1V L;  5IYB L;  3HJW B;  1IU5 A;  2Y0S P;  1ODH A;  4AI0 A;  4A3I L;  2CKC A;  1Z92 B;  1QCV A;  1JYB A;  2APO B;  3MSU A;  3LWO B;  5IP7 L;  1PFY A;  4U67 1;  3PKJ A;  3KYV A;  1K83 L;  2PVX A;  3HOZ L;  5M5W L;  3HOU L;  1S24 A;  5IYC L;  3PKI A;  5MGN A;  4LHL A;  2PVE A;  1RB9 A;  2LCQ A;  2M6O A;  2V0E A;  5JVG 1;  4BY1 L;  2JA8 L;  4AR4 A;  5C44 L;  1IRO A;  5C4X L;  4Y7N L;  2A6H D;  8RXN A;  2E2I L;  1C09 A;  2PMZ P;  4AR5 A;  2C6A A;  3H9C A;  4A3F L;  4JAF A;  1CAD A;  4A93 L;  2VL6 A;  3VPB E;  3PL5 A;  3MPS A;  4A3B L;  5JVH 1;  3PZA A;  1WCM L;  3P2A A;  3KYU A;  1TWH L;  5MFZ A;  5GAG c;  3RZD L;  2WAQ P;  1PZX A;  4V19 6;  1PFV A;  3GTM L;  1T9O A;  4A3J L;  3B0A B;  5M3M L;  2L0Z A;  3KYW A;  1S30 A;  1NXE A;  2E2J L;  1YK4 A;  5M5Y L;  2NVX L;  4E6Y A;  2NVQ L;  1QQT A;  4BBR L;  2HVY C;  3H99 A;  3GTP L;  3H9B A;  1BE7 A;  5MF6 A;  4ZN3 B;  1YK5 A;  2KKD A;  2QL0 A;  1YUZ A;  4AI3 A;  3S2H L;  1R9T L;  1ZRP A;  1RYT A;  1LTL A;  3QVD A;  3HJY B;  2AQC A;  1BQ8 A;  2M4V A;  1TWA L;  2C6B A;  3HOW L;  2B5I D;  3PO3 L;  1IRN A;  1VZH A;  4POG A;  2K2D A;  4LHN A;  1E8J A;  5GAD c;  4AHX A;  3H3V M;  2DSX A;  1VCX A;  4RXN A;  3GTJ L;  5FLM L;  2XJV A;  3WWN B;  2KN9 A;  5GAH c;  2Z3Q B;  3FKI L;  2HR5 A;  1YUX A;  2A69 D;  5MLC 3;  3S1M L;  2XJQ A;  1T9P A;  5RXN A;  5AI3 A;  3GTL L;  4A3D L;  5MFP A;  3CQZ L;  3PIP 1;  3I4N L;  2JA7 L;  3MQK B;  5C3E L;  2EY4 E;  4A3C L;  1BQ9 A;  3J7Z 1;  1B71 A;  1RDV A;  4A3G L;  3HKZ P;  4UY8 1;  1B13 A;  3P8B A;  3PIO 1;  4JAD A;  3GTK L;  4WFN 1;  5EIN C;  2H12 A;  2M4Y A;  3LWQ B;  2M6P A;  1LKO A;  3K7A L;  4JAE A;  2PPT A;  1I6H L;  4XXB B;  7RXN A;  3M4O L;  4Y52 L;  4JAG A;  4K9F A;  1FHH A;  3S17 L;  1SMU A;  5AN9 H;  3B08 B;  1TWG L;  3ZG6 A;  5IY0 A;  4A3E L;  4GS7 D;  3KYX A;  3A44 A;  1FHM A;  1VZI A;  5EIO C;  3S16 L;  3LWP B;  5IP9 L;  1IU6 A;  4YWM A;  3IU3 I;  1R0H A;  4AHZ A;  1IW7 D;  1SFO L;  1Y1W L;  2ERS A;  1R0I A;  3RYG A;  3S15 L;  1T9Q A;  3SS2 A; 
#chains in the Genus database with same CATH homology
 3MQK B;  2HVY C;  3LWO B;  2AQC A;  3LWV B;  3LWR B;  2EY4 E;  3LWQ B;  3HAX C;  3HJW B;  2RFK B;  3HJY B;  2AUS B;  3LWP B;  2APO B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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