3LWVB

Structure of h/aca rnp bound to a substrate rna containing 2'-deoxyuridine
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
53
structure length
53
Chain Sequence
FRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase .
pubmed doi rcsb
molecule keywords Pseudouridine synthase Cbf5
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
total genus 7
structure length 53
sequence length 53
ec nomenclature
pdb deposition date 2010-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF04135 Nop10p Nucleolar RNA-binding protein, Nop10p family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.40 Mainly Beta Single Sheet Rubrerythrin, domain 2 H/ACA ribonucleoprotein complex, subunit Nop10 3lwvB00
2AQCA 2APOB 3MQKB 3HJYB 3LWOB 3HAXC 3LWVB 2AUSB 2EY4E 3HJWB 3LWRB 2RFKB 2HVYC 3LWPB 3LWQB
chains in the Genus database with same CATH superfamily
1IROA 1QQTA 1PZXA 3H99A 3S17L 1IW7D 4A3ML 4YWMA 5C4JL 2PPTA 3CQZL 5GAGc 5C3EL 2A6ED 1BFYA 4JADA 1DVBA 2R92L 5DM61 3HOXL 3GTKL 4A3FL 4AYBP 2AYJA 3KYYA 1T9QA 1VZGA 1YUXA 4K9FA 5GAEc 4AR5A 3HOVL 2PYAA 3PZAA 2YU9L 1NXEA 2HR5A 3LPEB 4POFA 3P8BA 3H97A 5AN9H 4C2M1 4Y7NL 2MS3A 1SMMA 4C3JL 1S30A 3GTQL 3LNLA 1F4LA 1B2JA 1FHHA 2WAQP 1ZRPA 3FKIL 4BBSL 3I4NL 1VZIA 4YWLA 4C3IL 3S1QL 1PFWA 5C44L 1I50L 1BQ9A 5M5XL 3QVDA 2XJSA 2PMZP 2GMGA 1R0FA 4AHYA 5EINC 3RZ6A 1IU5A 2AQCA 3HOZL 1RB9A 2E2IL 4BY1L 5IY0A 4ZN3B 5MFPA 3S1RL 3K35A 4AR4A 2A6HD 3HKZP 4AI0A 5MFZA 1C09A 8RXNA 2RFKB 4X6AL 2APOB 1RWDA 4AI2A 2XJUA 2CKCA 5IYDL 2JA7L 1NNQA 4G6BA 1SMUA 5JVH1 5IYCL 3ZG6A 3PWFA 3HJYB 3S1NL 6RXNA 2K2DA 5M3FL 2PVEA 2RDVA 1OWBA 2JI2A 3H9BA 4E6YA 3KYXA 5M3ML 1ODHA 1TWHL 3S2DL 4A3BL 2R7ZL 3GTGL 1LKPA 1NXGA 3LWOB 4AR6A 2ZIXA 1YUZA 1R0GA 2XJTA 2M6OA 1S24A 3WWNB 4AHWA 4A3KL 4TPUA 3HOYL 5JVG1 3PL5A 4POGA 3FDJA 4QIWP 2XJPA 2KN9A 2KKDA 3H3VM 3B08B 4A3JL 4A93L 4A3DL 2QL0A 1CAAA 1CADA 1RDGA 1PFUA 2AUSB 3LWRB 3KYVA 3WWLA 4XGHA 5H1Sc 2JI1A 4BXXL 2NVYL 3S15L 1LKOA 2ERSA 2NVXL 2L0ZA 4C3HL 2JA6L 2WB1P 1SMWA 3PKIA 1S2ZA 5GADc 2VUML 3S2HL 1R0HA 2JA8L 2Y0SP 3QQCE 1DX8A 3HJWB 2XJRA 4AI3A 5FJ8L 3GTLL 5DM71 1IU6A 2PVXA 2H12A 1LKMA 1Z92B 4UY81 1YK4A 4WFN1 2XJVA 4V196 5EIOC 2PSMC 4JAGA 3MQKB 3RYGA 2A69D 4LHNA 2LCQA 3KYUA 1T9OA 2A68D 2B63L 1TWFL 1B71A 1YK5A 1R9TL 3JR7A 2E2JL 1BRFA 1T9PA 2NYDA 2M6PA 1BQ8A 2BE5D 1R0JA 1FHMA 2CR8A 4AR3A 2V0EA 3GTPL 5M5WL 5AI2A 3KYWA 1I3QL 1WCML 3A44A 5K2ME 3HAXC 4LHLA 1LTLA 3H9CA 3M4OL 5IP9L 1IRNA 3S14L 5M5YL 3SS2A 3M3YL 2V0FA 3GTJL 4AHXA 4ZN1B 4A3IL 1I6HL 1TWCL 3PO3L 4B8CD 1BE7A 2J9UB 4RXNA 3RZTA 3GTOL 3HOWL 4GS7D 5GAHc 3PO2L 3GTML 4U671 2JI3A 7RXNA 5IYBL 4A3LL 2Z3QB 1PFYA 3VPBE 2V3BB 4A3GL 5C4XL 1RDVA 1P7PA 3S16L 5MF6A 1PFVA 3IU3I 1RYTA 1VCXA 4JAFA 4BY7L 4A3EL 3S1ML 1WJVA 1E8JA 3NFPI 1OWCA 5IP7L 3PIP1 2JA5L 1H7VA 4BBRL 2CKAA 5AI3A 3PIO1 1QYBA 3J7Y1 2VL6A 2M4VA 2HVYC 1SFOL 1JYBA 3B0AB 2NVQL 1Y1VL 3PKJA 3MSUA 2O5JD 3LWPB 1RYQA 4Y52L 2C6AA 1YV1A 1TWGL 3RZOL 2EY4E 1VZHA 3I4ML 4TVMA 5MLC3 5MGNA 2Z3RB 1B2OA 4ME3A 2E2HL 2ERJA 4AHZA 2XJQA 3K7AL 1Y1WL 3RZDL 2NVTL 3MPSA 5FLML 2R93L 1K83L 4JAEA 5RXNA 2DSXA 4AI1A 1TWAL 2M4YA 3P2AA 3HOUL 2C6BA 4A3CL 1B13A 2B5ID 1R0IA 3LWQB 3LWVB 4XXBB 3H0GL 3J7Z1 1QCVA
chains in the Genus database with same CATH topology
2AQCA 2APOB 3MQKB 3HJYB 3LWOB 3HAXC 3LWVB 2AUSB 2EY4E 3HJWB 3LWRB 2RFKB 2HVYC 3LWPB 3LWQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AQC A;  2APO B;  3MQK B;  3HJY B;  3LWO B;  3HAX C;  3LWV B;  2AUS B;  2EY4 E;  3HJW B;  3LWR B;  2RFK B;  2HVY C;  3LWP B;  3LWQ B; 
#chains in the Genus database with same CATH topology
 1IRO A;  1QQT A;  1PZX A;  3H99 A;  3S17 L;  1IW7 D;  4A3M L;  4YWM A;  5C4J L;  2PPT A;  3CQZ L;  5GAG c;  5C3E L;  2A6E D;  1BFY A;  4JAD A;  1DVB A;  2R92 L;  5DM6 1;  3HOX L;  3GTK L;  4A3F L;  4AYB P;  2AYJ A;  3KYY A;  1T9Q A;  1VZG A;  1YUX A;  4K9F A;  5GAE c;  4AR5 A;  3HOV L;  2PYA A;  3PZA A;  2YU9 L;  1NXE A;  2HR5 A;  3LPE B;  4POF A;  3P8B A;  3H97 A;  5AN9 H;  4C2M 1;  4Y7N L;  2MS3 A;  1SMM A;  4C3J L;  1S30 A;  3GTQ L;  3LNL A;  1F4L A;  1B2J A;  1FHH A;  2WAQ P;  1ZRP A;  3FKI L;  4BBS L;  3I4N L;  1VZI A;  4YWL A;  4C3I L;  3S1Q L;  1PFW A;  5C44 L;  1I50 L;  1BQ9 A;  5M5X L;  3QVD A;  2XJS A;  2PMZ P;  2GMG A;  1R0F A;  4AHY A;  5EIN C;  3RZ6 A;  1IU5 A;  2AQC A;  3HOZ L;  1RB9 A;  2E2I L;  4BY1 L;  5IY0 A;  4ZN3 B;  5MFP A;  3S1R L;  3K35 A;  4AR4 A;  2A6H D;  3HKZ P;  4AI0 A;  5MFZ A;  1C09 A;  8RXN A;  2RFK B;  4X6A L;  2APO B;  1RWD A;  4AI2 A;  2XJU A;  2CKC A;  5IYD L;  2JA7 L;  1NNQ A;  4G6B A;  1SMU A;  5JVH 1;  5IYC L;  3ZG6 A;  3PWF A;  3HJY B;  3S1N L;  6RXN A;  2K2D A;  5M3F L;  2PVE A;  2RDV A;  1OWB A;  2JI2 A;  3H9B A;  4E6Y A;  3KYX A;  5M3M L;  1ODH A;  1TWH L;  3S2D L;  4A3B L;  2R7Z L;  3GTG L;  1LKP A;  1NXG A;  3LWO B;  4AR6 A;  2ZIX A;  1YUZ A;  1R0G A;  2XJT A;  2M6O A;  1S24 A;  3WWN B;  4AHW A;  4A3K L;  4TPU A;  3HOY L;  5JVG 1;  3PL5 A;  4POG A;  3FDJ A;  4QIW P;  2XJP A;  2KN9 A;  2KKD A;  3H3V M;  3B08 B;  4A3J L;  4A93 L;  4A3D L;  2QL0 A;  1CAA A;  1CAD A;  1RDG A;  1PFU A;  2AUS B;  3LWR B;  3KYV A;  3WWL A;  4XGH A;  5H1S c;  2JI1 A;  4BXX L;  2NVY L;  3S15 L;  1LKO A;  2ERS A;  2NVX L;  2L0Z A;  4C3H L;  2JA6 L;  2WB1 P;  1SMW A;  3PKI A;  1S2Z A;  5GAD c;  2VUM L;  3S2H L;  1R0H A;  2JA8 L;  2Y0S P;  3QQC E;  1DX8 A;  3HJW B;  2XJR A;  4AI3 A;  5FJ8 L;  3GTL L;  5DM7 1;  1IU6 A;  2PVX A;  2H12 A;  1LKM A;  1Z92 B;  4UY8 1;  1YK4 A;  4WFN 1;  2XJV A;  4V19 6;  5EIO C;  2PSM C;  4JAG A;  3MQK B;  3RYG A;  2A69 D;  4LHN A;  2LCQ A;  3KYU A;  1T9O A;  2A68 D;  2B63 L;  1TWF L;  1B71 A;  1YK5 A;  1R9T L;  3JR7 A;  2E2J L;  1BRF A;  1T9P A;  2NYD A;  2M6P A;  1BQ8 A;  2BE5 D;  1R0J A;  1FHM A;  2CR8 A;  4AR3 A;  2V0E A;  3GTP L;  5M5W L;  5AI2 A;  3KYW A;  1I3Q L;  1WCM L;  3A44 A;  5K2M E;  3HAX C;  4LHL A;  1LTL A;  3H9C A;  3M4O L;  5IP9 L;  1IRN A;  3S14 L;  5M5Y L;  3SS2 A;  3M3Y L;  2V0F A;  3GTJ L;  4AHX A;  4ZN1 B;  4A3I L;  1I6H L;  1TWC L;  3PO3 L;  4B8C D;  1BE7 A;  2J9U B;  4RXN A;  3RZT A;  3GTO L;  3HOW L;  4GS7 D;  5GAH c;  3PO2 L;  3GTM L;  4U67 1;  2JI3 A;  7RXN A;  5IYB L;  4A3L L;  2Z3Q B;  1PFY A;  3VPB E;  2V3B B;  4A3G L;  5C4X L;  1RDV A;  1P7P A;  3S16 L;  5MF6 A;  1PFV A;  3IU3 I;  1RYT A;  1VCX A;  4JAF A;  4BY7 L;  4A3E L;  3S1M L;  1WJV A;  1E8J A;  3NFP I;  1OWC A;  5IP7 L;  3PIP 1;  2JA5 L;  1H7V A;  4BBR L;  2CKA A;  5AI3 A;  3PIO 1;  1QYB A;  3J7Y 1;  2VL6 A;  2M4V A;  2HVY C;  1SFO L;  1JYB A;  3B0A B;  2NVQ L;  1Y1V L;  3PKJ A;  3MSU A;  2O5J D;  3LWP B;  1RYQ A;  4Y52 L;  2C6A A;  1YV1 A;  1TWG L;  3RZO L;  2EY4 E;  1VZH A;  3I4M L;  4TVM A;  5MLC 3;  5MGN A;  2Z3R B;  1B2O A;  4ME3 A;  2E2H L;  2ERJ A;  4AHZ A;  2XJQ A;  3K7A L;  1Y1W L;  3RZD L;  2NVT L;  3MPS A;  5FLM L;  2R93 L;  1K83 L;  4JAE A;  5RXN A;  2DSX A;  4AI1 A;  1TWA L;  2M4Y A;  3P2A A;  3HOU L;  2C6B A;  4A3C L;  1B13 A;  2B5I D;  1R0I A;  3LWQ B;  3LWV B;  4XXB B;  3H0G L;  3J7Z 1;  1QCV A; 
#chains in the Genus database with same CATH homology
 2AQC A;  2APO B;  3MQK B;  3HJY B;  3LWO B;  3HAX C;  3LWV B;  2AUS B;  2EY4 E;  3HJW B;  3LWR B;  2RFK B;  2HVY C;  3LWP B;  3LWQ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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