3M4EA

Crystal structure of the m113n mutant of alpha-hemolysin bound to beta-cyclodextrin
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYNSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Alpha-hemolysin
publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 57
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m4eA00
4IZLA 3B07A 3M3RA 3M4EA 4IYTA 4P1XA 3M2LA 4TW1A 2YGTA 3M4DA 3B07B 4P24A 4IYCA 4P1XB 4P1YA 5K59C 5K59A 2QK7A 3LKFA 4Q7GA 2LKFA 4TW1B 4YHDA 3ROHA 4J0OA 4P1YB 3O44A 2QK7B 7AHLA 4H56A 4IYAA 1LKFA 4U6VA 1T5RA 4IDJA 4I0NA 3ANZA 1PVLA
chains in the Genus database with same CATH superfamily
4IZLA 3B07A 3M3RA 3M4EA 4IYTA 4P1XA 3M2LA 4TW1A 2YGTA 3M4DA 3B07B 4P24A 4IYCA 4P1XB 4P1YA 5K59C 5K59A 2QK7A 3LKFA 4Q7GA 2LKFA 4TW1B 4YHDA 1XEZA 3ROHA 4J0OA 4P1YB 3O44A 2QK7B 7AHLA 4H56A 4IYAA 1LKFA 4U6VA 1T5RA 4IDJA 4I0NA 3ANZA 1PVLA
chains in the Genus database with same CATH topology
4IZLA 3B07A 3M3RA 3M4EA 4IYTA 4P1XA 3M2LA 4TW1A 2YGTA 3M4DA 3B07B 4P24A 4IYCA 4P1XB 4P1YA 5K59C 5K59A 2QK7A 3LKFA 4Q7GA 2LKFA 4TW1B 4YHDA 3ROHA 4J0OA 4P1YB 3O44A 2QK7B 7AHLA 4H56A 4IYAA 1LKFA 4U6VA 1T5RA 4IDJA 4I0NA 3ANZA 1PVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IZL A;  3B07 A;  3M3R A;  3M4E A;  4IYT A;  4P1X A;  3M2L A;  4TW1 A;  2YGT A;  3M4D A;  3B07 B;  4P24 A;  4IYC A;  4P1X B;  4P1Y A;  5K59 C;  5K59 A;  2QK7 A;  3LKF A;  4Q7G A;  2LKF A;  4TW1 B;  4YHD A;  3ROH A;  4J0O A;  4P1Y B;  3O44 A;  2QK7 B;  7AHL A;  4H56 A;  4IYA A;  1LKF A;  4U6V A;  1T5R A;  4IDJ A;  4I0N A;  3ANZ A;  1PVL A; 
#chains in the Genus database with same CATH topology
 4IZL A;  3B07 A;  3M3R A;  3M4E A;  4IYT A;  4P1X A;  3M2L A;  4TW1 A;  2YGT A;  3M4D A;  3B07 B;  4P24 A;  4IYC A;  4P1X B;  4P1Y A;  5K59 C;  5K59 A;  2QK7 A;  3LKF A;  4Q7G A;  2LKF A;  4TW1 B;  4YHD A;  1XEZ A;  3ROH A;  4J0O A;  4P1Y B;  3O44 A;  2QK7 B;  7AHL A;  4H56 A;  4IYA A;  1LKF A;  4U6V A;  1T5R A;  4IDJ A;  4I0N A;  3ANZ A;  1PVL A; 
#chains in the Genus database with same CATH homology
 4IZL A;  3B07 A;  3M3R A;  3M4E A;  4IYT A;  4P1X A;  3M2L A;  4TW1 A;  2YGT A;  3M4D A;  3B07 B;  4P24 A;  4IYC A;  4P1X B;  4P1Y A;  5K59 C;  5K59 A;  2QK7 A;  3LKF A;  4Q7G A;  2LKF A;  4TW1 B;  4YHD A;  3ROH A;  4J0O A;  4P1Y B;  3O44 A;  2QK7 B;  7AHL A;  4H56 A;  4IYA A;  1LKF A;  4U6V A;  1T5R A;  4IDJ A;  4I0N A;  3ANZ A;  1PVL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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