3M7PA

Fibronectin fragment
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
308
structure length
301
Chain Sequence
QPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Zinc Induces Structural Reorganization of Gelatin Binding Domain from Human Fibronectin and Affects Collagen Binding
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords FN1 protein
total genus 66
structure length 301
sequence length 308
ec nomenclature
pdb deposition date 2010-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00039 fn1 Fibronectin type I domain
A PF00040 fn2 Fibronectin type II domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3m7pA03
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 3m7pA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3m7pA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3m7pA04
4JHSA 4YNXA 1EAKA 1HCCA 2KMSA 1FBRA 2V5OA 2RLPA 3O8EB 1G4GA 1TPGA 2XWBF 3TVJA 1H8PA 4FXGG 2LOJA 2XRDA 3NFPI 1Z92B 5FO8C 3ZRZA 3OEDC 1TPMA 2EC3A 1VVDA 2CG7A 2IZ3A 1O9AA 1OK9A 1ELVA 1GKNA 3IX0A 1CK7A 1QUBA 1TPNA 2V8EA 2YBYA 1NWVA 1QO6A 3ZD1A 1GPZA 3OXUD 1GKGA 3KXVA 3RJ3D 5HZPB 4DJZA 2B5ID 1SS2A 1PDCA 1H2QP 3MQLA 4ONTD 2MCZA 2UWNA 4B2SA 3GOVA 1L6JA 3IU3I 2CKUA 3L89M 2CG6A 1KS0A 4B2RA 1PPQA 1J7MA 4C16A 4F4OC 4KKDA 4CSYA 3ZD2A 2W80A 1U5MA 1VVCA 1G4FA 4AYIA 1E5GA 1GHQB 1SRZA 1E88A 1OK3A 1E8BA 3KZJA 2RKYA 4IGDA 2EHFA 1OK1A 4ZH1D 3SW0X 2FN2A 1ZJKA 4J38B 2JRAA 5HYPA 2ERJA 1MD8A 1H03P 2IZ4A 1GXDA 3INBC 4LOTA 3EJHA 3T5OA 2XWJI 1C1ZA 4A5WB 2RKZA 1OJYA 2WIIC 1MD7A 2KRIA 2A55A 3ERBA 4AYEA 1H04P 3GXEA 1OJWA 1QGBA 4K12A 2QY0A 1UOTP 2BZMA 4WJG2 1OK2A 1LY2A 1HFHA 4MUCA 3M7PA 4LOSA 5HYUB 2JGWA 1HFIA 4AYMA 5HYTB 1CKLA 2W81A 3CALA 2G7IA 1OJVA 3R62A 2RL0A 5I0QB 1Q3XA 2YRAA 2O39C 2RLQA 1CXWA 2MCYA 4PZ5A 2XRBA 5JPMG 2XQWC 1H2PP 2JGXA 3OP8A 4AYDA
chains in the Genus database with same CATH superfamily
1O6IA 1E6RA 4JHSA 4HMDA 4YNXA 1EAKA 1HCCA 4IJEA 2KMSA 1FBRA 2V5OA 2RLPA 5DN5A 2IOUA 2I2LA 3N3FA 4TX8A 4OJLA 3WD3A 3O8EB 1G4GA 3WD4A 1W1YA 4Z2KA 1TPGA 1GOIA 4NZ4A 2XWBF 4Z2HA 3TVJA 3NJAA 4NZ5A 1H8PA 4HMCA 4FXGG 2LOJA 2XRDA 3NFPI 4BWCA 3WSYA 3F6KA 1Z92B 5FO8C 2Y2PA 3ZRZA 3OEDC 4OJOA 1TPMA 2Y8TA 2EC3A 1VVDA 2CG7A 2IZ3A 3FGTA 1O9AA 1OK9A 4IBKA 4Z2IA 3L29A 3WD2A 2Y2OA 1YU3A 3CI0J 2X2ZA 1ELVA 1GKNA 3IX0A 1CK7A 1QUBA 4NZ1A 1TPNA 4LG2A 3KS8A 1ED7A 2V8EA 1E6PA 2YBYA 1NWVA 1QO6A 1E15A 3ZD1A 1GPZA 2Y2LA 3OXUD 1H0IA 4OJ5A 1GKGA 3L2AA 2Y2NA 3KXVA 1UR9A 3RJ3D 5HZPB 1YU4A 4DJZA 2B5ID 4HMEA 1SS2A 1PDCA 4GHLA 3L26A 2XD5A 3MQLA 4IBBA 3L27A 1H2QP 1H0GA 4IJFA 2MCZA 2UWNA 4ONTD 2BG1A 1E6NA 4B2SA 3GOVA 2D49A 1L6JA 3IU3I 5DN4A 2UWXA 3HONA 4QNLA 2Y2KA 2CKUA 1RLHA 2CG6A 3FGRA 3K3TA 3L89M 1KS0A 4B2RA 1PPQA 1J7MA 4C16A 4F4OC 4KKDA 4CSYA 2Y8RA 1OGGA 3ZD2A 2Y2QA 1U5MA 1VVCA 2W80A 4OJPA 2FFFB 4AYIA 1E5GA 1G4FA 1GHQB 1SRZA 1E88A 1OK3A 1E6ZA 3WD0A 4GHAA 1E8BA 3KZJA 2RKYA 4IGDA 2EHFA 1OK1A 4ZH1D 3SW0X 2FN2A 1ZJKA 1YUEA 4J38B 2JRAA 5HYPA 2ERJA 4NYYA 1MD8A 1H03P 2IZ4A 4IBDA 1GXDA 3INBC 1AIWA 4YIZA 4LOTA 1YU0A 3EJHA 2Y8SA 1OGBA 1YU1A 3L28A 2Y2GA 4N7EA 2XWJI 3T5OA 4NZ3A 1C1ZA 2JE5A 4PO7A 2RKZA 3WSXA 4A5WB 3WX7A 4Z2GA 1OJYA 2WIIC 1UR8A 1MD7A 2KRIA 3ZLDA 2Y2IA 2A55A 3ERBA 4AYEA 1H04P 4IBCA 4Z2JA 3GXEA 1OJWA 4GH9A 1QGBA 2Y2HA 4IBGA 4K12A 2QY0A 2JCHA 5BPVA 1UOTP 2BZMA 4WJG2 3HSHA 1OK2A 4OUIA 1LY2A 1GPFA 1HFHA 4IBEA 4MSLA 4MUCA 3M7PA 4LOSA 3ZLEA 2JGWA 5HYUB 1W1PA 3FKEA 2RTSA 4IBFA 4MB5A 1HFIA 4NYUA 1CKLA 4AYMA 2W81A 2ZYCA 5HYTB 3CALA 2G7IA 1OJVA 3R62A 4Z2LA 3VWOA 2XD1A 4MB3A 2RL0A 5I0QB 1W1VA 1YU2A 1Q3XA 4IBJA 1W1TA 4OJ6A 3KS4A 2O39C 2RLQA 2YRAA 2Y2MA 1CXWA 4NY2A 2MCYA 2Y2JA 4PZ5A 4APLA 2XRBA 3L25A 5JPMG 2XQWC 1H2PP 2JGXA 4IBIA 3OP8A 3WD1A 4AYDA 4MB4A
chains in the Genus database with same CATH topology
4JHSA 4YNXA 1EAKA 1HCCA 2KMSA 1FBRA 2V5OA 2RLPA 3O8EB 1G4GA 1TPGA 2XWBF 3TVJA 1H8PA 4FXGG 2LOJA 2XRDA 3NFPI 1Z92B 5FO8C 3ZRZA 3OEDC 1TPMA 2EC3A 1VVDA 2CG7A 2IZ3A 1O9AA 1OK9A 1ELVA 1GKNA 3IX0A 1CK7A 1QUBA 1TPNA 2V8EA 2YBYA 1NWVA 1QO6A 3ZD1A 1GPZA 3OXUD 1GKGA 3KXVA 3RJ3D 5HZPB 4DJZA 2B5ID 1SS2A 1PDCA 1H2QP 3MQLA 4ONTD 2MCZA 2UWNA 4B2SA 3GOVA 1L6JA 3IU3I 2CKUA 3L89M 2CG6A 1KS0A 4B2RA 1PPQA 1J7MA 4C16A 4F4OC 4KKDA 4CSYA 3ZD2A 2W80A 1U5MA 1VVCA 1G4FA 4AYIA 1E5GA 1GHQB 1SRZA 1E88A 1OK3A 1E8BA 3KZJA 2RKYA 4IGDA 2EHFA 1OK1A 4ZH1D 3SW0X 2FN2A 1ZJKA 4J38B 2JRAA 5HYPA 2ERJA 1MD8A 1H03P 2IZ4A 1GXDA 3INBC 4LOTA 3EJHA 3T5OA 2XWJI 1C1ZA 4A5WB 2RKZA 1OJYA 2WIIC 1MD7A 2KRIA 2A55A 3ERBA 4AYEA 1H04P 3GXEA 1OJWA 1QGBA 4K12A 2QY0A 1UOTP 2BZMA 4WJG2 1OK2A 1LY2A 1HFHA 4MUCA 3M7PA 4LOSA 5HYUB 2JGWA 1HFIA 4AYMA 5HYTB 1CKLA 2W81A 3CALA 2G7IA 1OJVA 3R62A 2RL0A 5I0QB 1Q3XA 2YRAA 2O39C 2RLQA 1CXWA 2MCYA 4PZ5A 2XRBA 5JPMG 2XQWC 1H2PP 2JGXA 3OP8A 4AYDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JHS A;  4YNX A;  1EAK A;  1HCC A;  2KMS A;  1FBR A;  2V5O A;  2RLP A;  3O8E B;  1G4G A;  1TPG A;  2XWB F;  3TVJ A;  1H8P A;  4FXG G;  2LOJ A;  2XRD A;  3NFP I;  1Z92 B;  5FO8 C;  3ZRZ A;  3OED C;  1TPM A;  2EC3 A;  1VVD A;  2CG7 A;  2IZ3 A;  1O9A A;  1OK9 A;  1ELV A;  1GKN A;  3IX0 A;  1CK7 A;  1QUB A;  1TPN A;  2V8E A;  2YBY A;  1NWV A;  1QO6 A;  3ZD1 A;  1GPZ A;  3OXU D;  1GKG A;  3KXV A;  3RJ3 D;  5HZP B;  4DJZ A;  2B5I D;  1SS2 A;  1PDC A;  1H2Q P;  3MQL A;  4ONT D;  2MCZ A;  2UWN A;  4B2S A;  3GOV A;  1L6J A;  3IU3 I;  2CKU A;  3L89 M;  2CG6 A;  1KS0 A;  4B2R A;  1PPQ A;  1J7M A;  4C16 A;  4F4O C;  4KKD A;  4CSY A;  3ZD2 A;  2W80 A;  1U5M A;  1VVC A;  1G4F A;  4AYI A;  1E5G A;  1GHQ B;  1SRZ A;  1E88 A;  1OK3 A;  1E8B A;  3KZJ A;  2RKY A;  4IGD A;  2EHF A;  1OK1 A;  4ZH1 D;  3SW0 X;  2FN2 A;  1ZJK A;  4J38 B;  2JRA A;  5HYP A;  2ERJ A;  1MD8 A;  1H03 P;  2IZ4 A;  1GXD A;  3INB C;  4LOT A;  3EJH A;  3T5O A;  2XWJ I;  1C1Z A;  4A5W B;  2RKZ A;  1OJY A;  2WII C;  1MD7 A;  2KRI A;  2A55 A;  3ERB A;  4AYE A;  1H04 P;  3GXE A;  1OJW A;  1QGB A;  4K12 A;  2QY0 A;  1UOT P;  2BZM A;  4WJG 2;  1OK2 A;  1LY2 A;  1HFH A;  4MUC A;  3M7P A;  4LOS A;  5HYU B;  2JGW A;  1HFI A;  4AYM A;  5HYT B;  1CKL A;  2W81 A;  3CAL A;  2G7I A;  1OJV A;  3R62 A;  2RL0 A;  5I0Q B;  1Q3X A;  2YRA A;  2O39 C;  2RLQ A;  1CXW A;  2MCY A;  4PZ5 A;  2XRB A;  5JPM G;  2XQW C;  1H2P P;  2JGX A;  3OP8 A;  4AYD A; 
#chains in the Genus database with same CATH topology
 1O6I A;  1E6R A;  4JHS A;  4HMD A;  4YNX A;  1EAK A;  1HCC A;  4IJE A;  2KMS A;  1FBR A;  2V5O A;  2RLP A;  5DN5 A;  2IOU A;  2I2L A;  3N3F A;  4TX8 A;  4OJL A;  3WD3 A;  3O8E B;  1G4G A;  3WD4 A;  1W1Y A;  4Z2K A;  1TPG A;  1GOI A;  4NZ4 A;  2XWB F;  4Z2H A;  3TVJ A;  3NJA A;  4NZ5 A;  1H8P A;  4HMC A;  4FXG G;  2LOJ A;  2XRD A;  3NFP I;  4BWC A;  3WSY A;  3F6K A;  1Z92 B;  5FO8 C;  2Y2P A;  3ZRZ A;  3OED C;  4OJO A;  1TPM A;  2Y8T A;  2EC3 A;  1VVD A;  2CG7 A;  2IZ3 A;  3FGT A;  1O9A A;  1OK9 A;  4IBK A;  4Z2I A;  3L29 A;  3WD2 A;  2Y2O A;  1YU3 A;  3CI0 J;  2X2Z A;  1ELV A;  1GKN A;  3IX0 A;  1CK7 A;  1QUB A;  4NZ1 A;  1TPN A;  4LG2 A;  3KS8 A;  1ED7 A;  2V8E A;  1E6P A;  2YBY A;  1NWV A;  1QO6 A;  1E15 A;  3ZD1 A;  1GPZ A;  2Y2L A;  3OXU D;  1H0I A;  4OJ5 A;  1GKG A;  3L2A A;  2Y2N A;  3KXV A;  1UR9 A;  3RJ3 D;  5HZP B;  1YU4 A;  4DJZ A;  2B5I D;  4HME A;  1SS2 A;  1PDC A;  4GHL A;  3L26 A;  2XD5 A;  3MQL A;  4IBB A;  3L27 A;  1H2Q P;  1H0G A;  4IJF A;  2MCZ A;  2UWN A;  4ONT D;  2BG1 A;  1E6N A;  4B2S A;  3GOV A;  2D49 A;  1L6J A;  3IU3 I;  5DN4 A;  2UWX A;  3HON A;  4QNL A;  2Y2K A;  2CKU A;  1RLH A;  2CG6 A;  3FGR A;  3K3T A;  3L89 M;  1KS0 A;  4B2R A;  1PPQ A;  1J7M A;  4C16 A;  4F4O C;  4KKD A;  4CSY A;  2Y8R A;  1OGG A;  3ZD2 A;  2Y2Q A;  1U5M A;  1VVC A;  2W80 A;  4OJP A;  2FFF B;  4AYI A;  1E5G A;  1G4F A;  1GHQ B;  1SRZ A;  1E88 A;  1OK3 A;  1E6Z A;  3WD0 A;  4GHA A;  1E8B A;  3KZJ A;  2RKY A;  4IGD A;  2EHF A;  1OK1 A;  4ZH1 D;  3SW0 X;  2FN2 A;  1ZJK A;  1YUE A;  4J38 B;  2JRA A;  5HYP A;  2ERJ A;  4NYY A;  1MD8 A;  1H03 P;  2IZ4 A;  4IBD A;  1GXD A;  3INB C;  1AIW A;  4YIZ A;  4LOT A;  1YU0 A;  3EJH A;  2Y8S A;  1OGB A;  1YU1 A;  3L28 A;  2Y2G A;  4N7E A;  2XWJ I;  3T5O A;  4NZ3 A;  1C1Z A;  2JE5 A;  4PO7 A;  2RKZ A;  3WSX A;  4A5W B;  3WX7 A;  4Z2G A;  1OJY A;  2WII C;  1UR8 A;  1MD7 A;  2KRI A;  3ZLD A;  2Y2I A;  2A55 A;  3ERB A;  4AYE A;  1H04 P;  4IBC A;  4Z2J A;  3GXE A;  1OJW A;  4GH9 A;  1QGB A;  2Y2H A;  4IBG A;  4K12 A;  2QY0 A;  2JCH A;  5BPV A;  1UOT P;  2BZM A;  4WJG 2;  3HSH A;  1OK2 A;  4OUI A;  1LY2 A;  1GPF A;  1HFH A;  4IBE A;  4MSL A;  4MUC A;  3M7P A;  4LOS A;  3ZLE A;  2JGW A;  5HYU B;  1W1P A;  3FKE A;  2RTS A;  4IBF A;  4MB5 A;  1HFI A;  4NYU A;  1CKL A;  4AYM A;  2W81 A;  2ZYC A;  5HYT B;  3CAL A;  2G7I A;  1OJV A;  3R62 A;  4Z2L A;  3VWO A;  2XD1 A;  4MB3 A;  2RL0 A;  5I0Q B;  1W1V A;  1YU2 A;  1Q3X A;  4IBJ A;  1W1T A;  4OJ6 A;  3KS4 A;  2O39 C;  2RLQ A;  2YRA A;  2Y2M A;  1CXW A;  4NY2 A;  2MCY A;  2Y2J A;  4PZ5 A;  4APL A;  2XRB A;  3L25 A;  5JPM G;  2XQW C;  1H2P P;  2JGX A;  4IBI A;  3OP8 A;  3WD1 A;  4AYD A;  4MB4 A; 
#chains in the Genus database with same CATH homology
 4JHS A;  4YNX A;  1EAK A;  1HCC A;  2KMS A;  1FBR A;  2V5O A;  2RLP A;  3O8E B;  1G4G A;  1TPG A;  2XWB F;  3TVJ A;  1H8P A;  4FXG G;  2LOJ A;  2XRD A;  3NFP I;  1Z92 B;  5FO8 C;  3ZRZ A;  3OED C;  1TPM A;  2EC3 A;  1VVD A;  2CG7 A;  2IZ3 A;  1O9A A;  1OK9 A;  1ELV A;  1GKN A;  3IX0 A;  1CK7 A;  1QUB A;  1TPN A;  2V8E A;  2YBY A;  1NWV A;  1QO6 A;  3ZD1 A;  1GPZ A;  3OXU D;  1GKG A;  3KXV A;  3RJ3 D;  5HZP B;  4DJZ A;  2B5I D;  1SS2 A;  1PDC A;  1H2Q P;  3MQL A;  4ONT D;  2MCZ A;  2UWN A;  4B2S A;  3GOV A;  1L6J A;  3IU3 I;  2CKU A;  3L89 M;  2CG6 A;  1KS0 A;  4B2R A;  1PPQ A;  1J7M A;  4C16 A;  4F4O C;  4KKD A;  4CSY A;  3ZD2 A;  2W80 A;  1U5M A;  1VVC A;  1G4F A;  4AYI A;  1E5G A;  1GHQ B;  1SRZ A;  1E88 A;  1OK3 A;  1E8B A;  3KZJ A;  2RKY A;  4IGD A;  2EHF A;  1OK1 A;  4ZH1 D;  3SW0 X;  2FN2 A;  1ZJK A;  4J38 B;  2JRA A;  5HYP A;  2ERJ A;  1MD8 A;  1H03 P;  2IZ4 A;  1GXD A;  3INB C;  4LOT A;  3EJH A;  3T5O A;  2XWJ I;  1C1Z A;  4A5W B;  2RKZ A;  1OJY A;  2WII C;  1MD7 A;  2KRI A;  2A55 A;  3ERB A;  4AYE A;  1H04 P;  3GXE A;  1OJW A;  1QGB A;  4K12 A;  2QY0 A;  1UOT P;  2BZM A;  4WJG 2;  1OK2 A;  1LY2 A;  1HFH A;  4MUC A;  3M7P A;  4LOS A;  5HYU B;  2JGW A;  1HFI A;  4AYM A;  5HYT B;  1CKL A;  2W81 A;  3CAL A;  2G7I A;  1OJV A;  3R62 A;  2RL0 A;  5I0Q B;  1Q3X A;  2YRA A;  2O39 C;  2RLQ A;  1CXW A;  2MCY A;  4PZ5 A;  2XRB A;  5JPM G;  2XQW C;  1H2P P;  2JGX A;  3OP8 A;  4AYD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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