3MATA

E.coli methionine aminopeptidase transition-state inhibitor complex
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
264
structure length
264
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 86
structure length 264
sequence length 264
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3matA00
4U6EA 3BIQA 2V3XA 1PV9A 3L24A 4FLLA 5D6FA 4Z7MA 4MATA 2GU7A 1XNZA 2BWUA 1YVMA 5FCFA 2NQ6A 1QZYA 5E5BA 1B59A 2BHCA 2BWTA 2Q93A 2Q96A 1YJ3A 3MR1A 2BWWA 1XGNA 3IU7A 4IKRA 1MATA 4U6JA 4U6WA 4IU6A 2IW2A 2BHAA 2B3HA 4IKSA 5CE6A 1R58A 4IKUA 4RZZA 4U6CA 1W2MA 3D27A 1A16A 2G6PA 1C21A 2ADUA 3MX6A 4OOKA 2MATA 4ZWPA 2EVMA 2GGCA 3S6BA 4FO8A 4FUKA 2BWXA 1XGSA 5CNXA 2BB7A 3FMQA 3MATA 2B3LA 2GU5A 4JUQA 2BN7A 2DFIA 3PKEA 3CTZA 2OAZA 4PNCA 2V3ZA 1QXWA 1N51A 1W7VA 4IPAA 4IKTA 2BWVA 4FKCA 4S2TP 4U69A 4QR8A 1WKMA 3BIPA 1KP0A 4PV4A 4S01A 5JHUA 3IG4A 5CDEA 1QXYA 3TAVA 5JI6A 2GG3A 1WN1A 2P98A 4U71A 4S2RP 2Q94A 1WL6A 4ZWUA 5FCHA 2GG0A 2Q95A 1WLRA 1WY2A 3PKCA 2EA2A 1C24A 2BHBA 4FLKA 5CDVA 1KQ9A 2GZ5A 1YW8A 2V6CA 3BITA 3PKDA 1YW9A 4HXXA 4KM3A 2GG9A 2GG2A 2BWYA 5CDLA 1XGOA 1Y1NA 4FLJA 3RORA 1O0XA 4U6ZA 2GGBA 2GG5A 2GTXA 4EGEA 4U76A 4R60A 4RZYA 1YW7A 3IU9A 4FO7A 1BN5A 3CB5A 1M35A 2ZSGA 1QXZA 2OKNA 2P9AA 1XGMA 2GG8A 3CB6A 2GU4A 5CLSA 2V3YA 1JAWA 2BWSA 5D6EA 1C23A 1BOAA 3PKAA 4U70A 1WL9A 4A6VA 3L7GA 4B28A 2GG7A 3FMRA 3FM3A 2NQ7A 3TB5A 1B6AA 2HOWA 4S00A 4U73A 1C27A 2EVOA 4IECA 2GA2A 4IDYA 3PKBA 4FLIA 4RGZ1 2BH3A 2GU6A 4ZNGA 2EA4A 1C22A 4ZWOA 1KQ0A 2EVCA 1WBQA 4U75A 5JFRA 3IU8A 4U1BA 1R5HA 2Q8KA 4IF7A 2BHDA 2Q92A 3RVAA 3Q6DA 5CIKA 1CHMA 4A6WA 2B3KA 2P99A 1R5GA
chains in the Genus database with same CATH superfamily
4U6EA 3BIQA 2V3XA 1PV9A 3L24A 4FLLA 5D6FA 4Z7MA 4MATA 2GU7A 1XNZA 2BWUA 1YVMA 5FCFA 2NQ6A 1QZYA 5E5BA 1B59A 2BHCA 2BWTA 2Q93A 2Q96A 1YJ3A 3MR1A 2BWWA 1XGNA 3IU7A 4IKRA 1MATA 4U6JA 4U6WA 4IU6A 2IW2A 2BHAA 2B3HA 4IKSA 5CE6A 1R58A 4IKUA 4RZZA 4U6CA 1W2MA 3D27A 1A16A 2G6PA 1C21A 2ADUA 3MX6A 4OOKA 2MATA 4ZWPA 2EVMA 2GGCA 3S6BA 4FO8A 4FUKA 2BWXA 1XGSA 5CNXA 2BB7A 3FMQA 3MATA 2B3LA 2GU5A 4JUQA 2BN7A 2DFIA 3PKEA 3CTZA 2OAZA 4PNCA 2V3ZA 1QXWA 1N51A 1W7VA 4IPAA 4IKTA 2BWVA 4FKCA 4S2TP 4U69A 4QR8A 1WKMA 3BIPA 1KP0A 4PV4A 4S01A 5JHUA 3IG4A 5CDEA 1QXYA 3TAVA 5JI6A 2GG3A 1WN1A 2P98A 4U71A 4S2RP 2Q94A 1WL6A 4ZWUA 5FCHA 2GG0A 2Q95A 1WLRA 1WY2A 3PKCA 2EA2A 1C24A 2BHBA 4FLKA 5CDVA 1KQ9A 2GZ5A 1YW8A 2V6CA 3BITA 3PKDA 1YW9A 4HXXA 4KM3A 2GG9A 2GG2A 2BWYA 5CDLA 1XGOA 1Y1NA 4FLJA 3RORA 1O0XA 4U6ZA 2GGBA 2GG5A 2GTXA 4EGEA 4U76A 4R60A 4RZYA 1YW7A 3IU9A 4FO7A 1BN5A 3CB5A 1M35A 2ZSGA 1QXZA 2OKNA 2P9AA 1XGMA 2GG8A 3CB6A 2GU4A 5CLSA 2V3YA 1JAWA 2BWSA 5D6EA 1C23A 1BOAA 3PKAA 4U70A 1WL9A 4A6VA 3L7GA 4B28A 2GG7A 3FMRA 3FM3A 2NQ7A 3TB5A 1B6AA 2HOWA 4S00A 4U73A 1C27A 2EVOA 4IECA 2GA2A 4IDYA 3PKBA 4FLIA 4RGZ1 2BH3A 2GU6A 4ZNGA 2EA4A 1C22A 4ZWOA 1KQ0A 2EVCA 1WBQA 4U75A 5JFRA 3IU8A 4U1BA 1R5HA 2Q8KA 4IF7A 2BHDA 2Q92A 3RVAA 3Q6DA 5CIKA 1CHMA 4A6WA 2B3KA 2P99A 1R5GA
chains in the Genus database with same CATH topology
4U6EA 3BIQA 2V3XA 1PV9A 3L24A 4FLLA 5D6FA 4Z7MA 4MATA 2GU7A 1XNZA 2BWUA 1YVMA 5FCFA 2NQ6A 1QZYA 5E5BA 1B59A 2BHCA 2BWTA 2Q93A 2Q96A 1YJ3A 3MR1A 2BWWA 1XGNA 3IU7A 4IKRA 1MATA 4U6JA 4U6WA 4IU6A 2IW2A 2BHAA 2B3HA 4IKSA 5CE6A 1R58A 4IKUA 4RZZA 4U6CA 1W2MA 3D27A 1A16A 2G6PA 1C21A 2ADUA 3MX6A 4OOKA 2MATA 4ZWPA 2EVMA 2GGCA 3S6BA 4FO8A 4FUKA 2BWXA 1XGSA 5CNXA 2BB7A 3FMQA 3MATA 2B3LA 2GU5A 4JUQA 2BN7A 2DFIA 3PKEA 3CTZA 2OAZA 4PNCA 2V3ZA 1QXWA 1N51A 1W7VA 4IPAA 4IKTA 2BWVA 4FKCA 4S2TP 4U69A 4QR8A 1WKMA 3BIPA 1KP0A 4PV4A 4S01A 5JHUA 3IG4A 5CDEA 1QXYA 3TAVA 5JI6A 2GG3A 1WN1A 2P98A 4U71A 4S2RP 2Q94A 1WL6A 4ZWUA 5FCHA 2GG0A 2Q95A 1WLRA 1WY2A 3PKCA 2EA2A 1C24A 2BHBA 4FLKA 5CDVA 1KQ9A 2GZ5A 1YW8A 2V6CA 3BITA 3PKDA 1YW9A 4HXXA 4KM3A 2GG9A 2GG2A 2BWYA 5CDLA 1XGOA 1Y1NA 4FLJA 3RORA 1O0XA 4U6ZA 2GGBA 2GG5A 2GTXA 4EGEA 4U76A 4R60A 4RZYA 1YW7A 3IU9A 4FO7A 1BN5A 3CB5A 1M35A 2ZSGA 1QXZA 2OKNA 2P9AA 1XGMA 2GG8A 3CB6A 2GU4A 5CLSA 2V3YA 1JAWA 2BWSA 5D6EA 1C23A 1BOAA 3PKAA 4U70A 1WL9A 4A6VA 3L7GA 4B28A 2GG7A 3FMRA 3FM3A 2NQ7A 3TB5A 1B6AA 2HOWA 4S00A 4U73A 1C27A 2EVOA 4IECA 2GA2A 4IDYA 3PKBA 4FLIA 4RGZ1 2BH3A 2GU6A 4ZNGA 2EA4A 1C22A 4ZWOA 1KQ0A 2EVCA 1WBQA 4U75A 5JFRA 3IU8A 4U1BA 1R5HA 2Q8KA 4IF7A 2BHDA 2Q92A 3RVAA 3Q6DA 5CIKA 1CHMA 4A6WA 2B3KA 2P99A 1R5GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6E A;  3BIQ A;  2V3X A;  1PV9 A;  3L24 A;  4FLL A;  5D6F A;  4Z7M A;  4MAT A;  2GU7 A;  1XNZ A;  2BWU A;  1YVM A;  5FCF A;  2NQ6 A;  1QZY A;  5E5B A;  1B59 A;  2BHC A;  2BWT A;  2Q93 A;  2Q96 A;  1YJ3 A;  3MR1 A;  2BWW A;  1XGN A;  3IU7 A;  4IKR A;  1MAT A;  4U6J A;  4U6W A;  4IU6 A;  2IW2 A;  2BHA A;  2B3H A;  4IKS A;  5CE6 A;  1R58 A;  4IKU A;  4RZZ A;  4U6C A;  1W2M A;  3D27 A;  1A16 A;  2G6P A;  1C21 A;  2ADU A;  3MX6 A;  4OOK A;  2MAT A;  4ZWP A;  2EVM A;  2GGC A;  3S6B A;  4FO8 A;  4FUK A;  2BWX A;  1XGS A;  5CNX A;  2BB7 A;  3FMQ A;  3MAT A;  2B3L A;  2GU5 A;  4JUQ A;  2BN7 A;  2DFI A;  3PKE A;  3CTZ A;  2OAZ A;  4PNC A;  2V3Z A;  1QXW A;  1N51 A;  1W7V A;  4IPA A;  4IKT A;  2BWV A;  4FKC A;  4S2T P;  4U69 A;  4QR8 A;  1WKM A;  3BIP A;  1KP0 A;  4PV4 A;  4S01 A;  5JHU A;  3IG4 A;  5CDE A;  1QXY A;  3TAV A;  5JI6 A;  2GG3 A;  1WN1 A;  2P98 A;  4U71 A;  4S2R P;  2Q94 A;  1WL6 A;  4ZWU A;  5FCH A;  2GG0 A;  2Q95 A;  1WLR A;  1WY2 A;  3PKC A;  2EA2 A;  1C24 A;  2BHB A;  4FLK A;  5CDV A;  1KQ9 A;  2GZ5 A;  1YW8 A;  2V6C A;  3BIT A;  3PKD A;  1YW9 A;  4HXX A;  4KM3 A;  2GG9 A;  2GG2 A;  2BWY A;  5CDL A;  1XGO A;  1Y1N A;  4FLJ A;  3ROR A;  1O0X A;  4U6Z A;  2GGB A;  2GG5 A;  2GTX A;  4EGE A;  4U76 A;  4R60 A;  4RZY A;  1YW7 A;  3IU9 A;  4FO7 A;  1BN5 A;  3CB5 A;  1M35 A;  2ZSG A;  1QXZ A;  2OKN A;  2P9A A;  1XGM A;  2GG8 A;  3CB6 A;  2GU4 A;  5CLS A;  2V3Y A;  1JAW A;  2BWS A;  5D6E A;  1C23 A;  1BOA A;  3PKA A;  4U70 A;  1WL9 A;  4A6V A;  3L7G A;  4B28 A;  2GG7 A;  3FMR A;  3FM3 A;  2NQ7 A;  3TB5 A;  1B6A A;  2HOW A;  4S00 A;  4U73 A;  1C27 A;  2EVO A;  4IEC A;  2GA2 A;  4IDY A;  3PKB A;  4FLI A;  4RGZ 1;  2BH3 A;  2GU6 A;  4ZNG A;  2EA4 A;  1C22 A;  4ZWO A;  1KQ0 A;  2EVC A;  1WBQ A;  4U75 A;  5JFR A;  3IU8 A;  4U1B A;  1R5H A;  2Q8K A;  4IF7 A;  2BHD A;  2Q92 A;  3RVA A;  3Q6D A;  5CIK A;  1CHM A;  4A6W A;  2B3K A;  2P99 A;  1R5G A; 
#chains in the Genus database with same CATH topology
 4U6E A;  3BIQ A;  2V3X A;  1PV9 A;  3L24 A;  4FLL A;  5D6F A;  4Z7M A;  4MAT A;  2GU7 A;  1XNZ A;  2BWU A;  1YVM A;  5FCF A;  2NQ6 A;  1QZY A;  5E5B A;  1B59 A;  2BHC A;  2BWT A;  2Q93 A;  2Q96 A;  1YJ3 A;  3MR1 A;  2BWW A;  1XGN A;  3IU7 A;  4IKR A;  1MAT A;  4U6J A;  4U6W A;  4IU6 A;  2IW2 A;  2BHA A;  2B3H A;  4IKS A;  5CE6 A;  1R58 A;  4IKU A;  4RZZ A;  4U6C A;  1W2M A;  3D27 A;  1A16 A;  2G6P A;  1C21 A;  2ADU A;  3MX6 A;  4OOK A;  2MAT A;  4ZWP A;  2EVM A;  2GGC A;  3S6B A;  4FO8 A;  4FUK A;  2BWX A;  1XGS A;  5CNX A;  2BB7 A;  3FMQ A;  3MAT A;  2B3L A;  2GU5 A;  4JUQ A;  2BN7 A;  2DFI A;  3PKE A;  3CTZ A;  2OAZ A;  4PNC A;  2V3Z A;  1QXW A;  1N51 A;  1W7V A;  4IPA A;  4IKT A;  2BWV A;  4FKC A;  4S2T P;  4U69 A;  4QR8 A;  1WKM A;  3BIP A;  1KP0 A;  4PV4 A;  4S01 A;  5JHU A;  3IG4 A;  5CDE A;  1QXY A;  3TAV A;  5JI6 A;  2GG3 A;  1WN1 A;  2P98 A;  4U71 A;  4S2R P;  2Q94 A;  1WL6 A;  4ZWU A;  5FCH A;  2GG0 A;  2Q95 A;  1WLR A;  1WY2 A;  3PKC A;  2EA2 A;  1C24 A;  2BHB A;  4FLK A;  5CDV A;  1KQ9 A;  2GZ5 A;  1YW8 A;  2V6C A;  3BIT A;  3PKD A;  1YW9 A;  4HXX A;  4KM3 A;  2GG9 A;  2GG2 A;  2BWY A;  5CDL A;  1XGO A;  1Y1N A;  4FLJ A;  3ROR A;  1O0X A;  4U6Z A;  2GGB A;  2GG5 A;  2GTX A;  4EGE A;  4U76 A;  4R60 A;  4RZY A;  1YW7 A;  3IU9 A;  4FO7 A;  1BN5 A;  3CB5 A;  1M35 A;  2ZSG A;  1QXZ A;  2OKN A;  2P9A A;  1XGM A;  2GG8 A;  3CB6 A;  2GU4 A;  5CLS A;  2V3Y A;  1JAW A;  2BWS A;  5D6E A;  1C23 A;  1BOA A;  3PKA A;  4U70 A;  1WL9 A;  4A6V A;  3L7G A;  4B28 A;  2GG7 A;  3FMR A;  3FM3 A;  2NQ7 A;  3TB5 A;  1B6A A;  2HOW A;  4S00 A;  4U73 A;  1C27 A;  2EVO A;  4IEC A;  2GA2 A;  4IDY A;  3PKB A;  4FLI A;  4RGZ 1;  2BH3 A;  2GU6 A;  4ZNG A;  2EA4 A;  1C22 A;  4ZWO A;  1KQ0 A;  2EVC A;  1WBQ A;  4U75 A;  5JFR A;  3IU8 A;  4U1B A;  1R5H A;  2Q8K A;  4IF7 A;  2BHD A;  2Q92 A;  3RVA A;  3Q6D A;  5CIK A;  1CHM A;  4A6W A;  2B3K A;  2P99 A;  1R5G A; 
#chains in the Genus database with same CATH homology
 4U6E A;  3BIQ A;  2V3X A;  1PV9 A;  3L24 A;  4FLL A;  5D6F A;  4Z7M A;  4MAT A;  2GU7 A;  1XNZ A;  2BWU A;  1YVM A;  5FCF A;  2NQ6 A;  1QZY A;  5E5B A;  1B59 A;  2BHC A;  2BWT A;  2Q93 A;  2Q96 A;  1YJ3 A;  3MR1 A;  2BWW A;  1XGN A;  3IU7 A;  4IKR A;  1MAT A;  4U6J A;  4U6W A;  4IU6 A;  2IW2 A;  2BHA A;  2B3H A;  4IKS A;  5CE6 A;  1R58 A;  4IKU A;  4RZZ A;  4U6C A;  1W2M A;  3D27 A;  1A16 A;  2G6P A;  1C21 A;  2ADU A;  3MX6 A;  4OOK A;  2MAT A;  4ZWP A;  2EVM A;  2GGC A;  3S6B A;  4FO8 A;  4FUK A;  2BWX A;  1XGS A;  5CNX A;  2BB7 A;  3FMQ A;  3MAT A;  2B3L A;  2GU5 A;  4JUQ A;  2BN7 A;  2DFI A;  3PKE A;  3CTZ A;  2OAZ A;  4PNC A;  2V3Z A;  1QXW A;  1N51 A;  1W7V A;  4IPA A;  4IKT A;  2BWV A;  4FKC A;  4S2T P;  4U69 A;  4QR8 A;  1WKM A;  3BIP A;  1KP0 A;  4PV4 A;  4S01 A;  5JHU A;  3IG4 A;  5CDE A;  1QXY A;  3TAV A;  5JI6 A;  2GG3 A;  1WN1 A;  2P98 A;  4U71 A;  4S2R P;  2Q94 A;  1WL6 A;  4ZWU A;  5FCH A;  2GG0 A;  2Q95 A;  1WLR A;  1WY2 A;  3PKC A;  2EA2 A;  1C24 A;  2BHB A;  4FLK A;  5CDV A;  1KQ9 A;  2GZ5 A;  1YW8 A;  2V6C A;  3BIT A;  3PKD A;  1YW9 A;  4HXX A;  4KM3 A;  2GG9 A;  2GG2 A;  2BWY A;  5CDL A;  1XGO A;  1Y1N A;  4FLJ A;  3ROR A;  1O0X A;  4U6Z A;  2GGB A;  2GG5 A;  2GTX A;  4EGE A;  4U76 A;  4R60 A;  4RZY A;  1YW7 A;  3IU9 A;  4FO7 A;  1BN5 A;  3CB5 A;  1M35 A;  2ZSG A;  1QXZ A;  2OKN A;  2P9A A;  1XGM A;  2GG8 A;  3CB6 A;  2GU4 A;  5CLS A;  2V3Y A;  1JAW A;  2BWS A;  5D6E A;  1C23 A;  1BOA A;  3PKA A;  4U70 A;  1WL9 A;  4A6V A;  3L7G A;  4B28 A;  2GG7 A;  3FMR A;  3FM3 A;  2NQ7 A;  3TB5 A;  1B6A A;  2HOW A;  4S00 A;  4U73 A;  1C27 A;  2EVO A;  4IEC A;  2GA2 A;  4IDY A;  3PKB A;  4FLI A;  4RGZ 1;  2BH3 A;  2GU6 A;  4ZNG A;  2EA4 A;  1C22 A;  4ZWO A;  1KQ0 A;  2EVC A;  1WBQ A;  4U75 A;  5JFR A;  3IU8 A;  4U1B A;  1R5H A;  2Q8K A;  4IF7 A;  2BHD A;  2Q92 A;  3RVA A;  3Q6D A;  5CIK A;  1CHM A;  4A6W A;  2B3K A;  2P99 A;  1R5G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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