3MK5A

Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from mycobacterium tuberculosis with sulfate and zinc at ph 4.00
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
207
structure length
191
Chain Sequence
HMTRLDSVERAVADIAAGKAVIVIDDEDEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 61
structure length 191
sequence length 207
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mk5A00
3LQUA 3MGZA 3MK5A 1PVWA 2RISA 1K7JA 3LRJA 4P6PA 4P6CA 1IEZA 2MX1A 1HRUA 4P8JA 4P6DA 1K4IA 2EQAA 3AJEA 1K49A 1K4LA 1TKSA 4P77A 1G57A 1G58A 2RIUA 4I14A 1KK9A 3LS6A 4P8EA 1PVYA 3H07A 3L7VA 3MIOA 4FFJA 1K4PA 1K4OA 4E1BA 1JCUA 1TKUA 1SNNA
chains in the Genus database with same CATH superfamily
3VTIA 3LQUA 3TTDA 3MGZA 3MK5A 1PVWA 2RISA 1K7JA 3LRJA 4P6PA 4P6CA 1IEZA 2MX1A 1HRUA 4P8JA 3TTFA 3VF4A 4P6DA 1K4IA 2EQAA 3AJEA 3VEXA 1K49A 3TSQA 1K4LA 3TSUA 3TTCA 3VERA 1TKSA 4P77A 1G57A 1G58A 2RIUA 4I14A 3VEZA 1KK9A 3LS6A 4P8EA 1PVYA 3H07A 3L7VA 3VTHA 3VESA 3VEOA 3VETA 3MIOA 4FFJA 1K4PA 3TSPA 1K4OA 3VEWA 3VENA 4E1BA 1JCUA 1TKUA 3VF2A 1SNNA
chains in the Genus database with same CATH topology
3VTIA 3LQUA 3TTDA 3MGZA 3MK5A 1PVWA 2RISA 1K7JA 3LRJA 4P6PA 4P6CA 1IEZA 2MX1A 1HRUA 4P8JA 3TTFA 3VF4A 4P6DA 1K4IA 2EQAA 3AJEA 3VEXA 1K49A 3TSQA 1K4LA 3TSUA 3TTCA 3VERA 1TKSA 4P77A 1G57A 1G58A 2RIUA 4I14A 3VEZA 1KK9A 3LS6A 4P8EA 1PVYA 3H07A 3L7VA 3VTHA 3VESA 3VEOA 3VETA 3MIOA 4FFJA 1K4PA 3TSPA 1K4OA 3VEWA 3VENA 4E1BA 1JCUA 1TKUA 3VF2A 1SNNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LQU A;  3MGZ A;  3MK5 A;  1PVW A;  2RIS A;  1K7J A;  3LRJ A;  4P6P A;  4P6C A;  1IEZ A;  2MX1 A;  1HRU A;  4P8J A;  4P6D A;  1K4I A;  2EQA A;  3AJE A;  1K49 A;  1K4L A;  1TKS A;  4P77 A;  1G57 A;  1G58 A;  2RIU A;  4I14 A;  1KK9 A;  3LS6 A;  4P8E A;  1PVY A;  3H07 A;  3L7V A;  3MIO A;  4FFJ A;  1K4P A;  1K4O A;  4E1B A;  1JCU A;  1TKU A;  1SNN A; 
#chains in the Genus database with same CATH topology
 3VTI A;  3LQU A;  3TTD A;  3MGZ A;  3MK5 A;  1PVW A;  2RIS A;  1K7J A;  3LRJ A;  4P6P A;  4P6C A;  1IEZ A;  2MX1 A;  1HRU A;  4P8J A;  3TTF A;  3VF4 A;  4P6D A;  1K4I A;  2EQA A;  3AJE A;  3VEX A;  1K49 A;  3TSQ A;  1K4L A;  3TSU A;  3TTC A;  3VER A;  1TKS A;  4P77 A;  1G57 A;  1G58 A;  2RIU A;  4I14 A;  3VEZ A;  1KK9 A;  3LS6 A;  4P8E A;  1PVY A;  3H07 A;  3L7V A;  3VTH A;  3VES A;  3VEO A;  3VET A;  3MIO A;  4FFJ A;  1K4P A;  3TSP A;  1K4O A;  3VEW A;  3VEN A;  4E1B A;  1JCU A;  1TKU A;  3VF2 A;  1SNN A; 
#chains in the Genus database with same CATH homology
 3VTI A;  3LQU A;  3TTD A;  3MGZ A;  3MK5 A;  1PVW A;  2RIS A;  1K7J A;  3LRJ A;  4P6P A;  4P6C A;  1IEZ A;  2MX1 A;  1HRU A;  4P8J A;  3TTF A;  3VF4 A;  4P6D A;  1K4I A;  2EQA A;  3AJE A;  3VEX A;  1K49 A;  3TSQ A;  1K4L A;  3TSU A;  3TTC A;  3VER A;  1TKS A;  4P77 A;  1G57 A;  1G58 A;  2RIU A;  4I14 A;  3VEZ A;  1KK9 A;  3LS6 A;  4P8E A;  1PVY A;  3H07 A;  3L7V A;  3VTH A;  3VES A;  3VEO A;  3VET A;  3MIO A;  4FFJ A;  1K4P A;  3TSP A;  1K4O A;  3VEW A;  3VEN A;  4E1B A;  1JCU A;  1TKU A;  3VF2 A;  1SNN A; 
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