3MR1A

Crystal structure of methionine aminopeptidase from rickettsia prowazekii
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
249
structure length
249
Chain Sequence
SMIKIHTEKDFIKMRAAGKLAAETLDFITDHVKPNVTTNSLNDLCHNFITSHNAIPAPLNYKGFPKSICTSINHVVCHGIPNDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQVTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIGRVFHDKPSILNYGRNGTGLTLKEGMFFTVEPMINAGNYDTILSKLDGWTVTTRDKSLSAQFEHTIGVTKDGFEIFTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
source organism Rickettsia prowazekii
molecule tags Hydrolase
total genus 79
structure length 249
sequence length 249
chains with identical sequence B, C, D
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3mr1A00
5D6FA 1C22A 2GG7A 2GTXA 2BHCA 1YJ3A 2BWVA 5CNXA 4IU6A 4U6ZA 2BHDA 2EVCA 1YVMA 4FLLA 2ZSGA 4RZYA 2P99A 5JI6A 2GG9A 2B3LA 3IU8A 2GU5A 3RVAA 4ZWUA 3TB5A 4U71A 4IKUA 2OKNA 5E5BA 2BB7A 1XGNA 4ZWPA 1B6AA 1O0XA 2GGCA 2GU4A 4RZZA 1KQ9A 1WY2A 2GZ5A 3TAVA 3PKBA 2EVOA 2GU7A 4RGZ1 1R58A 1N51A 4FLIA 1M35A 1XGOA 1YW9A 4FLKA 2GG2A 4PV4A 1QXWA 4HXXA 5FCHA 3FM3A 4FO8A 4S2RP 4A6VA 2BWYA 4U1BA 3PKAA 1C27A 1C21A 3MATA 4PNCA 4U6EA 2BWSA 1CHMA 2MATA 4FKCA 5CDLA 1KP0A 4U69A 4U6WA 2G6PA 4OOKA 3CTZA 2V3ZA 4QR8A 4A6WA 3IU9A 4U70A 3CB5A 2BWWA 2IW2A 3PKDA 2BWXA 1QZYA 1KQ0A 1PV9A 1WN1A 1Y1NA 4IPAA 1WBQA 1QXYA 2GGBA 3FMRA 5CIKA 1XNZA 3RORA 5JHUA 2Q95A 1YW8A 2BHBA 2Q94A 3D27A 4B28A 2V6CA 3BITA 3MX6A 1BOAA 3PKEA 3IU7A 4IKSA 4ZNGA 4MATA 2EA2A 4IDYA 1WL6A 3PKCA 2Q96A 2GA2A 3BIPA 2BWTA 4U75A 1W2MA 5JFRA 1W7VA 1C24A 1QXZA 2BN7A 4Z7MA 1B59A 1WL9A 4R60A 2Q8KA 2OAZA 3Q6DA 1WLRA 4U76A 5CLSA 4S2TP 4S01A 2GG0A 5CE6A 3S6BA 3IG4A 2P9AA 4IKTA 2NQ6A 2Q93A 4IKRA 2B3KA 2GG5A 3L24A 2P98A 2BWUA 2GG3A 2EVMA 2BHAA 2V3YA 4S00A 3L7GA 1XGMA 1WKMA 1BN5A 5CDVA 2GG8A 4KM3A 1R5GA 2NQ7A 4U6JA 4ZWOA 2DFIA 2B3HA 3MR1A 5D6EA 3BIQA 2HOWA 4U73A 1MATA 1XGSA 1A16A 2EA4A 1JAWA 1R5HA 4IF7A 4EGEA 1YW7A 5CDEA 2Q92A 4IECA 2ADUA 4JUQA 4FLJA 2BH3A 3CB6A 1C23A 4FUKA 2V3XA 4U6CA 3FMQA 2GU6A 4FO7A 5FCFA
chains in the Genus database with same CATH superfamily
5D6FA 1C22A 2GG7A 2GTXA 2BHCA 1YJ3A 2BWVA 5CNXA 4IU6A 4U6ZA 2BHDA 2EVCA 1YVMA 4FLLA 2ZSGA 4RZYA 2P99A 5JI6A 2GG9A 2B3LA 3IU8A 2GU5A 3RVAA 4ZWUA 3TB5A 4U71A 4IKUA 2OKNA 5E5BA 2BB7A 1XGNA 4ZWPA 1B6AA 1O0XA 2GGCA 2GU4A 4RZZA 1KQ9A 1WY2A 2GZ5A 3TAVA 3PKBA 2EVOA 2GU7A 4RGZ1 1R58A 1N51A 4FLIA 1M35A 1XGOA 1YW9A 4FLKA 2GG2A 4PV4A 1QXWA 4HXXA 5FCHA 3FM3A 4FO8A 4S2RP 4A6VA 2BWYA 4U1BA 3PKAA 1C27A 1C21A 3MATA 4PNCA 4U6EA 2BWSA 1CHMA 2MATA 4FKCA 5CDLA 1KP0A 4U69A 4U6WA 2G6PA 4OOKA 3CTZA 2V3ZA 4QR8A 4A6WA 3IU9A 4U70A 3CB5A 2BWWA 2IW2A 3PKDA 2BWXA 1QZYA 1KQ0A 1PV9A 1WN1A 1Y1NA 4IPAA 1WBQA 1QXYA 2GGBA 3FMRA 5CIKA 1XNZA 3RORA 5JHUA 2Q95A 1YW8A 2BHBA 2Q94A 3D27A 4B28A 2V6CA 3BITA 3MX6A 1BOAA 3PKEA 3IU7A 4IKSA 4ZNGA 4MATA 2EA2A 4IDYA 1WL6A 3PKCA 2Q96A 2GA2A 3BIPA 2BWTA 4U75A 1W2MA 5JFRA 1W7VA 1C24A 1QXZA 2BN7A 4Z7MA 1B59A 1WL9A 4R60A 2Q8KA 2OAZA 3Q6DA 1WLRA 4U76A 5CLSA 4S2TP 4S01A 2GG0A 5CE6A 3S6BA 3IG4A 2P9AA 4IKTA 2NQ6A 2Q93A 4IKRA 2B3KA 2GG5A 3L24A 2P98A 2BWUA 2GG3A 2EVMA 2BHAA 2V3YA 4S00A 3L7GA 1XGMA 1WKMA 1BN5A 5CDVA 2GG8A 4KM3A 1R5GA 2NQ7A 4U6JA 4ZWOA 2DFIA 2B3HA 3MR1A 5D6EA 3BIQA 2HOWA 4U73A 1MATA 1XGSA 1A16A 2EA4A 1JAWA 1R5HA 4IF7A 4EGEA 1YW7A 5CDEA 2Q92A 4IECA 2ADUA 4JUQA 4FLJA 2BH3A 3CB6A 1C23A 4FUKA 2V3XA 4U6CA 3FMQA 2GU6A 4FO7A 5FCFA
chains in the Genus database with same CATH topology
5D6FA 1C22A 2GG7A 2GTXA 2BHCA 1YJ3A 2BWVA 5CNXA 4IU6A 4U6ZA 2BHDA 2EVCA 1YVMA 4FLLA 2ZSGA 4RZYA 2P99A 5JI6A 2GG9A 2B3LA 3IU8A 2GU5A 3RVAA 4ZWUA 3TB5A 4U71A 4IKUA 2OKNA 5E5BA 2BB7A 1XGNA 4ZWPA 1B6AA 1O0XA 2GGCA 2GU4A 4RZZA 1KQ9A 1WY2A 2GZ5A 3TAVA 3PKBA 2EVOA 2GU7A 4RGZ1 1R58A 1N51A 4FLIA 1M35A 1XGOA 1YW9A 4FLKA 2GG2A 4PV4A 1QXWA 4HXXA 5FCHA 3FM3A 4FO8A 4S2RP 4A6VA 2BWYA 4U1BA 3PKAA 1C27A 1C21A 3MATA 4PNCA 4U6EA 2BWSA 1CHMA 2MATA 4FKCA 5CDLA 1KP0A 4U69A 4U6WA 2G6PA 4OOKA 3CTZA 2V3ZA 4QR8A 4A6WA 3IU9A 4U70A 3CB5A 2BWWA 2IW2A 3PKDA 2BWXA 1QZYA 1KQ0A 1PV9A 1WN1A 1Y1NA 4IPAA 1WBQA 1QXYA 2GGBA 3FMRA 5CIKA 1XNZA 3RORA 5JHUA 2Q95A 1YW8A 2BHBA 2Q94A 3D27A 4B28A 2V6CA 3BITA 3MX6A 1BOAA 3PKEA 3IU7A 4IKSA 4ZNGA 4MATA 2EA2A 4IDYA 1WL6A 3PKCA 2Q96A 2GA2A 3BIPA 2BWTA 4U75A 1W2MA 5JFRA 1W7VA 1C24A 1QXZA 2BN7A 4Z7MA 1B59A 1WL9A 4R60A 2Q8KA 2OAZA 3Q6DA 1WLRA 4U76A 5CLSA 4S2TP 4S01A 2GG0A 5CE6A 3S6BA 3IG4A 2P9AA 4IKTA 2NQ6A 2Q93A 4IKRA 2B3KA 2GG5A 3L24A 2P98A 2BWUA 2GG3A 2EVMA 2BHAA 2V3YA 4S00A 3L7GA 1XGMA 1WKMA 1BN5A 5CDVA 2GG8A 4KM3A 1R5GA 2NQ7A 4U6JA 4ZWOA 2DFIA 2B3HA 3MR1A 5D6EA 3BIQA 2HOWA 4U73A 1MATA 1XGSA 1A16A 2EA4A 1JAWA 1R5HA 4IF7A 4EGEA 1YW7A 5CDEA 2Q92A 4IECA 2ADUA 4JUQA 4FLJA 2BH3A 3CB6A 1C23A 4FUKA 2V3XA 4U6CA 3FMQA 2GU6A 4FO7A 5FCFA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5D6F A;  1C22 A;  2GG7 A;  2GTX A;  2BHC A;  1YJ3 A;  2BWV A;  5CNX A;  4IU6 A;  4U6Z A;  2BHD A;  2EVC A;  1YVM A;  4FLL A;  2ZSG A;  4RZY A;  2P99 A;  5JI6 A;  2GG9 A;  2B3L A;  3IU8 A;  2GU5 A;  3RVA A;  4ZWU A;  3TB5 A;  4U71 A;  4IKU A;  2OKN A;  5E5B A;  2BB7 A;  1XGN A;  4ZWP A;  1B6A A;  1O0X A;  2GGC A;  2GU4 A;  4RZZ A;  1KQ9 A;  1WY2 A;  2GZ5 A;  3TAV A;  3PKB A;  2EVO A;  2GU7 A;  4RGZ 1;  1R58 A;  1N51 A;  4FLI A;  1M35 A;  1XGO A;  1YW9 A;  4FLK A;  2GG2 A;  4PV4 A;  1QXW A;  4HXX A;  5FCH A;  3FM3 A;  4FO8 A;  4S2R P;  4A6V A;  2BWY A;  4U1B A;  3PKA A;  1C27 A;  1C21 A;  3MAT A;  4PNC A;  4U6E A;  2BWS A;  1CHM A;  2MAT A;  4FKC A;  5CDL A;  1KP0 A;  4U69 A;  4U6W A;  2G6P A;  4OOK A;  3CTZ A;  2V3Z A;  4QR8 A;  4A6W A;  3IU9 A;  4U70 A;  3CB5 A;  2BWW A;  2IW2 A;  3PKD A;  2BWX A;  1QZY A;  1KQ0 A;  1PV9 A;  1WN1 A;  1Y1N A;  4IPA A;  1WBQ A;  1QXY A;  2GGB A;  3FMR A;  5CIK A;  1XNZ A;  3ROR A;  5JHU A;  2Q95 A;  1YW8 A;  2BHB A;  2Q94 A;  3D27 A;  4B28 A;  2V6C A;  3BIT A;  3MX6 A;  1BOA A;  3PKE A;  3IU7 A;  4IKS A;  4ZNG A;  4MAT A;  2EA2 A;  4IDY A;  1WL6 A;  3PKC A;  2Q96 A;  2GA2 A;  3BIP A;  2BWT A;  4U75 A;  1W2M A;  5JFR A;  1W7V A;  1C24 A;  1QXZ A;  2BN7 A;  4Z7M A;  1B59 A;  1WL9 A;  4R60 A;  2Q8K A;  2OAZ A;  3Q6D A;  1WLR A;  4U76 A;  5CLS A;  4S2T P;  4S01 A;  2GG0 A;  5CE6 A;  3S6B A;  3IG4 A;  2P9A A;  4IKT A;  2NQ6 A;  2Q93 A;  4IKR A;  2B3K A;  2GG5 A;  3L24 A;  2P98 A;  2BWU A;  2GG3 A;  2EVM A;  2BHA A;  2V3Y A;  4S00 A;  3L7G A;  1XGM A;  1WKM A;  1BN5 A;  5CDV A;  2GG8 A;  4KM3 A;  1R5G A;  2NQ7 A;  4U6J A;  4ZWO A;  2DFI A;  2B3H A;  3MR1 A;  5D6E A;  3BIQ A;  2HOW A;  4U73 A;  1MAT A;  1XGS A;  1A16 A;  2EA4 A;  1JAW A;  1R5H A;  4IF7 A;  4EGE A;  1YW7 A;  5CDE A;  2Q92 A;  4IEC A;  2ADU A;  4JUQ A;  4FLJ A;  2BH3 A;  3CB6 A;  1C23 A;  4FUK A;  2V3X A;  4U6C A;  3FMQ A;  2GU6 A;  4FO7 A;  5FCF A; 
#chains in the Genus database with same CATH topology
 5D6F A;  1C22 A;  2GG7 A;  2GTX A;  2BHC A;  1YJ3 A;  2BWV A;  5CNX A;  4IU6 A;  4U6Z A;  2BHD A;  2EVC A;  1YVM A;  4FLL A;  2ZSG A;  4RZY A;  2P99 A;  5JI6 A;  2GG9 A;  2B3L A;  3IU8 A;  2GU5 A;  3RVA A;  4ZWU A;  3TB5 A;  4U71 A;  4IKU A;  2OKN A;  5E5B A;  2BB7 A;  1XGN A;  4ZWP A;  1B6A A;  1O0X A;  2GGC A;  2GU4 A;  4RZZ A;  1KQ9 A;  1WY2 A;  2GZ5 A;  3TAV A;  3PKB A;  2EVO A;  2GU7 A;  4RGZ 1;  1R58 A;  1N51 A;  4FLI A;  1M35 A;  1XGO A;  1YW9 A;  4FLK A;  2GG2 A;  4PV4 A;  1QXW A;  4HXX A;  5FCH A;  3FM3 A;  4FO8 A;  4S2R P;  4A6V A;  2BWY A;  4U1B A;  3PKA A;  1C27 A;  1C21 A;  3MAT A;  4PNC A;  4U6E A;  2BWS A;  1CHM A;  2MAT A;  4FKC A;  5CDL A;  1KP0 A;  4U69 A;  4U6W A;  2G6P A;  4OOK A;  3CTZ A;  2V3Z A;  4QR8 A;  4A6W A;  3IU9 A;  4U70 A;  3CB5 A;  2BWW A;  2IW2 A;  3PKD A;  2BWX A;  1QZY A;  1KQ0 A;  1PV9 A;  1WN1 A;  1Y1N A;  4IPA A;  1WBQ A;  1QXY A;  2GGB A;  3FMR A;  5CIK A;  1XNZ A;  3ROR A;  5JHU A;  2Q95 A;  1YW8 A;  2BHB A;  2Q94 A;  3D27 A;  4B28 A;  2V6C A;  3BIT A;  3MX6 A;  1BOA A;  3PKE A;  3IU7 A;  4IKS A;  4ZNG A;  4MAT A;  2EA2 A;  4IDY A;  1WL6 A;  3PKC A;  2Q96 A;  2GA2 A;  3BIP A;  2BWT A;  4U75 A;  1W2M A;  5JFR A;  1W7V A;  1C24 A;  1QXZ A;  2BN7 A;  4Z7M A;  1B59 A;  1WL9 A;  4R60 A;  2Q8K A;  2OAZ A;  3Q6D A;  1WLR A;  4U76 A;  5CLS A;  4S2T P;  4S01 A;  2GG0 A;  5CE6 A;  3S6B A;  3IG4 A;  2P9A A;  4IKT A;  2NQ6 A;  2Q93 A;  4IKR A;  2B3K A;  2GG5 A;  3L24 A;  2P98 A;  2BWU A;  2GG3 A;  2EVM A;  2BHA A;  2V3Y A;  4S00 A;  3L7G A;  1XGM A;  1WKM A;  1BN5 A;  5CDV A;  2GG8 A;  4KM3 A;  1R5G A;  2NQ7 A;  4U6J A;  4ZWO A;  2DFI A;  2B3H A;  3MR1 A;  5D6E A;  3BIQ A;  2HOW A;  4U73 A;  1MAT A;  1XGS A;  1A16 A;  2EA4 A;  1JAW A;  1R5H A;  4IF7 A;  4EGE A;  1YW7 A;  5CDE A;  2Q92 A;  4IEC A;  2ADU A;  4JUQ A;  4FLJ A;  2BH3 A;  3CB6 A;  1C23 A;  4FUK A;  2V3X A;  4U6C A;  3FMQ A;  2GU6 A;  4FO7 A;  5FCF A; 
#chains in the Genus database with same CATH homology
 5D6F A;  1C22 A;  2GG7 A;  2GTX A;  2BHC A;  1YJ3 A;  2BWV A;  5CNX A;  4IU6 A;  4U6Z A;  2BHD A;  2EVC A;  1YVM A;  4FLL A;  2ZSG A;  4RZY A;  2P99 A;  5JI6 A;  2GG9 A;  2B3L A;  3IU8 A;  2GU5 A;  3RVA A;  4ZWU A;  3TB5 A;  4U71 A;  4IKU A;  2OKN A;  5E5B A;  2BB7 A;  1XGN A;  4ZWP A;  1B6A A;  1O0X A;  2GGC A;  2GU4 A;  4RZZ A;  1KQ9 A;  1WY2 A;  2GZ5 A;  3TAV A;  3PKB A;  2EVO A;  2GU7 A;  4RGZ 1;  1R58 A;  1N51 A;  4FLI A;  1M35 A;  1XGO A;  1YW9 A;  4FLK A;  2GG2 A;  4PV4 A;  1QXW A;  4HXX A;  5FCH A;  3FM3 A;  4FO8 A;  4S2R P;  4A6V A;  2BWY A;  4U1B A;  3PKA A;  1C27 A;  1C21 A;  3MAT A;  4PNC A;  4U6E A;  2BWS A;  1CHM A;  2MAT A;  4FKC A;  5CDL A;  1KP0 A;  4U69 A;  4U6W A;  2G6P A;  4OOK A;  3CTZ A;  2V3Z A;  4QR8 A;  4A6W A;  3IU9 A;  4U70 A;  3CB5 A;  2BWW A;  2IW2 A;  3PKD A;  2BWX A;  1QZY A;  1KQ0 A;  1PV9 A;  1WN1 A;  1Y1N A;  4IPA A;  1WBQ A;  1QXY A;  2GGB A;  3FMR A;  5CIK A;  1XNZ A;  3ROR A;  5JHU A;  2Q95 A;  1YW8 A;  2BHB A;  2Q94 A;  3D27 A;  4B28 A;  2V6C A;  3BIT A;  3MX6 A;  1BOA A;  3PKE A;  3IU7 A;  4IKS A;  4ZNG A;  4MAT A;  2EA2 A;  4IDY A;  1WL6 A;  3PKC A;  2Q96 A;  2GA2 A;  3BIP A;  2BWT A;  4U75 A;  1W2M A;  5JFR A;  1W7V A;  1C24 A;  1QXZ A;  2BN7 A;  4Z7M A;  1B59 A;  1WL9 A;  4R60 A;  2Q8K A;  2OAZ A;  3Q6D A;  1WLR A;  4U76 A;  5CLS A;  4S2T P;  4S01 A;  2GG0 A;  5CE6 A;  3S6B A;  3IG4 A;  2P9A A;  4IKT A;  2NQ6 A;  2Q93 A;  4IKR A;  2B3K A;  2GG5 A;  3L24 A;  2P98 A;  2BWU A;  2GG3 A;  2EVM A;  2BHA A;  2V3Y A;  4S00 A;  3L7G A;  1XGM A;  1WKM A;  1BN5 A;  5CDV A;  2GG8 A;  4KM3 A;  1R5G A;  2NQ7 A;  4U6J A;  4ZWO A;  2DFI A;  2B3H A;  3MR1 A;  5D6E A;  3BIQ A;  2HOW A;  4U73 A;  1MAT A;  1XGS A;  1A16 A;  2EA4 A;  1JAW A;  1R5H A;  4IF7 A;  4EGE A;  1YW7 A;  5CDE A;  2Q92 A;  4IEC A;  2ADU A;  4JUQ A;  4FLJ A;  2BH3 A;  3CB6 A;  1C23 A;  4FUK A;  2V3X A;  4U6C A;  3FMQ A;  2GU6 A;  4FO7 A;  5FCF A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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