The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
86
|
sequence length |
276
|
structure length |
271
|
Chain Sequence |
SSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLVEECAPNTGQCHLCLPPSEPWDQTLGVVN
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Hydrolase
|
| molecule keywords |
A/G-specific adenine DNA glycosylase
|
| publication title |
A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions.
pubmed doi rcsb |
| source organism |
Homo sapiens
|
| total genus |
86
|
| structure length |
271
|
| sequence length |
276
|
| chains with identical sequence |
Y
|
| ec nomenclature |
ec
3.2.2.31: Adenine glycosylase. |
| pdb deposition date | 2010-05-25 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| X | PF00633 | HHH | Helix-hairpin-helix motif |
| X | PF00730 | HhH-GPD | HhH-GPD superfamily base excision DNA repair protein |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Endonuclease III; domain 1 | Hypothetical protein; domain 2 | ||
| Mainly Alpha | Orthogonal Bundle | Endonuclease Iii, domain 2 | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) |
#chains in the Genus database with same CATH superfamily 1EBM A; 4AI4 A; 1LWW A; 3KTU A; 1ORP A; 3CW7 A; 1WEG A; 1WEF A; 1RRS A; 4B22 A; 1LMZ A; 3FHG A; 4EJY A; 4UNF A; 1N39 A; 4EA4 A; 3OGD A; 1P59 A; 2NOL A; 1YQM A; 4E9F A; 1KG3 A; 1ORN A; 4OFH A; 4EW4 A; 2ABK A; 4EA5 A; 3FSP A; 1M3Q A; 4B21 A; 3I0X A; 1PU8 A; 2XHI A; 2NOH A; 2NOI A; 2OFK A; 1KO9 A; 2NOZ A; 1MUN A; 4OFA A; 4B23 A; 1KQJ A; 1M3H A; 1YQK A; 4YPH A; 1NGN A; 1XQO A; 3FHF A; 4E9H A; 1XQP A; 3CWS A; 1KG5 A; 1N3A A; 1MUD A; 1YQR A; 1P7M A; 3CVT A; 4EVV A; 5DPK A; 2JHN A; 3OH6 A; 1XG7 A; 3N5N X; 4HSB A; 3IH7 A; 3CWA A; 4PII A; 1DIZ A; 1PVS A; 1KG4 A; 1LWV A; 1KG2 A; 3OH9 A; 3KNT A; 1LWY A; 1KEA A; 1PU6 A; 4YPR A; 1KG7 A; 5AN4 A; 4OFE A; 2NOE A; 3D4V A; 4UOB A; 3CVS A; 3S6I A; 1N3C A; 2JHJ A; 4B24 A; 1FN7 A; 4YOQ A; 3G0Q A; 1PU7 A; 1WEI A; 1NKU A; 1RRQ A; 2I5W A; 4EW0 A; 5CHZ A; 2NOB A; 3IHO A; 2YG8 A; 4DK9 A; 3F0Z A; 3N0U A; 1YQL A; 2NOF A; 4EJZ A; 1HU0 A; 2JG6 A; 3CWU A; 5KN9 A; 3CWT A; 3F10 A; 4AI5 A; 2OFI A; 1KG6 A; 4E9E A; 1VRL A; 4AIA A; 1MPG A; 3I0W A; 1MUY A; 4E9G A; 5KN8 A; 2YG9 A; 2H56 A; #chains in the Genus database with same CATH topology 3OYC A; 1EBM A; 3S3M A; 4AI4 A; 3OYE A; 3KTU A; 1ORP A; 4ZTF A; 1LWW A; 3CW7 A; 4E7I A; 1WEG A; 1WEF A; 1RRS A; 4B22 A; 1LMZ A; 3OYJ A; 3OYI A; 3FHG A; 4EJY A; 4UNF A; 1N39 A; 4BE2 A; 4EA4 A; 3OGD A; 1P59 A; 2NOL A; 1YQM A; 4E9F A; 1KG3 A; 1ORN A; 3L2U A; 4E7K A; 3OYD A; 4OFH A; 4EW4 A; 2ABK A; 4EA5 A; 3FSP A; 1M3Q A; 3NNQ A; 4B21 A; 3I0X A; 1PU8 A; 5FRM A; 2XHI A; 2NOH A; 2NOI A; 5FRO A; 2OFK A; 4ZTJ A; 4BAC A; 3OYF A; 1KO9 A; 2NOZ A; 1MUN A; 2JPS A; 4OFA A; 3OYH A; 4B23 A; 1KQJ A; 4BDZ A; 1M3H A; 1YQK A; 4YPH A; 1NGN A; 3L2Q A; 3OS2 A; 1XQO A; 3OYA A; 3FHF A; 4E9H A; 3L2W A; 1XQP A; 3CWS A; 3OYN A; 1KG5 A; 4BE1 A; 1N3A A; 3VW4 A; 1MUD A; 1YQR A; 3R2X C; 1P7M A; 3OYB A; 3OYG A; 3CVT A; 4EVV A; 5DPK A; 2JHN A; 4NZG A; 3LCN A; 5FRN A; 4E7J A; 3OH6 A; 1XG7 A; 3N5N X; 4HSB A; 3IH7 A; 3CWA A; 4PII A; 1DIZ A; 3OY9 A; 1PVS A; 1KG4 A; 1LWV A; 3OS0 A; 1KG2 A; 3OH9 A; 3KNT A; 1LWY A; 1KEA A; 1PU6 A; 4YPR A; 1KG7 A; 4IKF A; 4BE0 A; 5AN4 A; 4OFE A; 4E7L A; 2NOE A; 3D4V A; 4BDY A; 4UOB A; 3CVS A; 3S6I A; 1N3C A; 2JHJ A; 4B24 A; 3OYM A; 4YOQ A; 3OS1 A; 3G0Q A; 1FN7 A; 3OYK A; 1PU7 A; 1U84 A; 1NKU A; 1WEI A; 1RRQ A; 2I5W A; 4EW0 A; 5CHZ A; 2NOB A; 3IHO A; 3L2R A; 2YG8 A; 4DK9 A; 3F0Z A; 3N0U A; 3OYL A; 2V75 A; 1YQL A; 2NOF A; 4EJZ A; 1HU0 A; 2JG6 A; 4E7H A; 3CWU A; 5KN9 A; 3CWT A; 3F10 A; 2W03 A; 4AI5 A; 2W04 A; 2OFI A; 1KG6 A; 4E9E A; 1VRL A; 4AIA A; 1MPG A; 3I0W A; 1MUY A; 4E9G A; 3S3N A; 3L2V A; 3S3O A; 5KN8 A; 2YG9 A; 2H56 A; #chains in the Genus database with same CATH homology 1EBM A; 4AI4 A; 1LWW A; 3KTU A; 1ORP A; 3CW7 A; 1WEG A; 1WEF A; 1RRS A; 4B22 A; 1LMZ A; 3FHG A; 4EJY A; 4UNF A; 1N39 A; 4EA4 A; 3OGD A; 1P59 A; 2NOL A; 1YQM A; 4E9F A; 1KG3 A; 1ORN A; 4OFH A; 4EW4 A; 2ABK A; 4EA5 A; 3FSP A; 1M3Q A; 4B21 A; 3I0X A; 1PU8 A; 2XHI A; 2NOH A; 2NOI A; 2OFK A; 1KO9 A; 2NOZ A; 1MUN A; 4OFA A; 4B23 A; 1KQJ A; 1M3H A; 1YQK A; 4YPH A; 1NGN A; 1XQO A; 3FHF A; 4E9H A; 1XQP A; 3CWS A; 1KG5 A; 1N3A A; 1MUD A; 1YQR A; 1P7M A; 3CVT A; 4EVV A; 5DPK A; 2JHN A; 3OH6 A; 1XG7 A; 3N5N X; 4HSB A; 3IH7 A; 3CWA A; 4PII A; 1DIZ A; 1PVS A; 1KG4 A; 1LWV A; 1KG2 A; 3OH9 A; 3KNT A; 1LWY A; 1KEA A; 1PU6 A; 4YPR A; 1KG7 A; 5AN4 A; 4OFE A; 2NOE A; 3D4V A; 4UOB A; 3CVS A; 3S6I A; 1N3C A; 2JHJ A; 4B24 A; 1FN7 A; 4YOQ A; 3G0Q A; 1PU7 A; 1WEI A; 1NKU A; 1RRQ A; 2I5W A; 4EW0 A; 5CHZ A; 2NOB A; 3IHO A; 2YG8 A; 4DK9 A; 3F0Z A; 3N0U A; 1YQL A; 2NOF A; 4EJZ A; 1HU0 A; 2JG6 A; 3CWU A; 5KN9 A; 3CWT A; 3F10 A; 4AI5 A; 2OFI A; 1KG6 A; 4E9E A; 1VRL A; 4AIA A; 1MPG A; 3I0W A; 1MUY A; 4E9G A; 5KN8 A; 2YG9 A; 2H56 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
