3N9VA

Crystal structure of inpp5b
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
303
structure length
300
Chain Sequence
MIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Type II inositol-1,4,5-trisphosphate 5-phosphatase
total genus 90
structure length 300
sequence length 303
chains with identical sequence B
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2010-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 3n9vA00
5A7IA 3W2YA 3FZIA 4B5JA 4FPVA 3G38A 4LNDA 5J3SA 4A9CA 3CJCD 3I5VA 3G8VA 4F1HB 1VYBA 5INOA 4B5IA 3I41A 4L1YA 1E9NA 2A42B 4F1IA 4PUQA 3NGOA 3I48A 3W2XA 2F1NA 5J42A 4CMLA 4GYZA 3G0AA 3NR8A 4JG3A 3G1KA 5J8NA 2A40B 1SI6X 2EI9A 3W3DB 4RUWA 4C1RA 2A3ZB 3DNIA 1BIXA 2JC5A 2D1KB 1I9ZA 5DG0A 3G6SA 4QHEA 1ZWXA 1ATND 5INMA 2V0RA 3L1WA 4AWNA 2UYRX 5J3ZA 1DE9A 4L1ZA 3I46A 4GZ0A 3G4TA 1SR4B 2IMQX 2ISIA 3NGNA 5CFEA 3G0RA 3G3CA 4B5FA 3GA6A 2DNJA 4F1RA 4B5GA 2V0SA 2O3CA 3N9VA 5DV2A 4QHDA 3G00A 5INNA 2J63A 1DE8A 4FVAA 2A41B 2XSWA 5INPA 2VOAA 4CMNA 1I9YA 4K6LF 1WDUA 1Y21A 2O3HA 5A7JA 4IEMA 5INKA 3G2CA 3MTCA 5DFJA 4F1HA 3G3YA 5J3PA 2DDSA 2DDRA 4L20A 2F2FB 2DDTA 4GZ1A 3WCXA 4GZ2A 1DEWA 4B5HA 3G2DA 5CFGA 3TEBA 5INLA 1YJHA 1AKOA 3MPRA 1HD7A 3K55A 4GEWA 5DFFA 3NGQA 5HT2A 4L21A 5DFIA 1DNKA 5EWTA 4B5MA 3U8UA 3G91A 5DV4A 5DFHA 4QH9A 5INQA 1NTFA 2JC4A
chains in the Genus database with same CATH superfamily
5A7IA 3W2YA 3FZIA 4B5JA 4FPVA 3G38A 4LNDA 5J3SA 4A9CA 3CJCD 3I5VA 3G8VA 4F1HB 1VYBA 5INOA 4B5IA 3I41A 4L1YA 1E9NA 2A42B 4F1IA 4PUQA 3NGOA 3I48A 3W2XA 2F1NA 5J42A 4CMLA 4GYZA 3G0AA 3NR8A 4JG3A 3G1KA 5J8NA 2A40B 1SI6X 2EI9A 3W3DB 4RUWA 4C1RA 2A3ZB 3DNIA 1BIXA 2JC5A 2D1KB 1I9ZA 5DG0A 3G6SA 4QHEA 1ZWXA 1ATND 5INMA 2V0RA 3L1WA 4AWNA 2UYRX 5J3ZA 1DE9A 4L1ZA 3I46A 4GZ0A 3G4TA 1SR4B 2IMQX 2ISIA 3NGNA 5CFEA 3G0RA 3G3CA 4B5FA 3GA6A 2DNJA 4F1RA 4B5GA 2V0SA 2O3CA 3N9VA 5DV2A 4QHDA 3G00A 5INNA 2J63A 1DE8A 4FVAA 2A41B 2XSWA 5INPA 2VOAA 4CMNA 1I9YA 4K6LF 1WDUA 1Y21A 2O3HA 5A7JA 4IEMA 5INKA 3G2CA 3MTCA 5DFJA 4F1HA 3G3YA 5J3PA 2DDSA 2DDRA 4L20A 2F2FB 2DDTA 4GZ1A 3WCXA 4GZ2A 1DEWA 4B5HA 3G2DA 5CFGA 3TEBA 5INLA 1YJHA 1AKOA 3MPRA 1HD7A 3K55A 4GEWA 5DFFA 3NGQA 5HT2A 4L21A 5DFIA 1DNKA 5EWTA 4B5MA 3U8UA 3G91A 5DV4A 5DFHA 4QH9A 5INQA 1NTFA 2JC4A
chains in the Genus database with same CATH topology
5A7IA 3W2YA 3FZIA 4B5JA 4FPVA 3G38A 4LNDA 5J3SA 4A9CA 3CJCD 3I5VA 3G8VA 4F1HB 1VYBA 5INOA 4B5IA 3I41A 4L1YA 1E9NA 2A42B 4F1IA 4PUQA 3NGOA 3I48A 3W2XA 2F1NA 5J42A 4CMLA 4GYZA 3G0AA 3NR8A 4JG3A 3G1KA 5J8NA 2A40B 1SI6X 2EI9A 3W3DB 4RUWA 4C1RA 2A3ZB 3DNIA 1BIXA 2JC5A 2D1KB 1I9ZA 5DG0A 3G6SA 4QHEA 1ZWXA 1ATND 5INMA 2V0RA 3L1WA 4AWNA 2UYRX 5J3ZA 1DE9A 4L1ZA 3I46A 4GZ0A 3G4TA 1SR4B 2IMQX 2ISIA 3NGNA 5CFEA 3G0RA 3G3CA 4B5FA 3GA6A 2DNJA 4F1RA 4B5GA 2V0SA 2O3CA 3N9VA 5DV2A 4QHDA 3G00A 5INNA 2J63A 1DE8A 4FVAA 2A41B 2XSWA 5INPA 2VOAA 4CMNA 1I9YA 4K6LF 1WDUA 1Y21A 2O3HA 5A7JA 4IEMA 5INKA 3G2CA 3MTCA 5DFJA 4F1HA 3G3YA 5J3PA 2DDSA 2DDRA 4L20A 2F2FB 2DDTA 4GZ1A 3WCXA 4GZ2A 1DEWA 4B5HA 3G2DA 5CFGA 3TEBA 5INLA 1YJHA 1AKOA 3MPRA 1HD7A 3K55A 4GEWA 5DFFA 3NGQA 5HT2A 4L21A 5DFIA 1DNKA 5EWTA 4B5MA 3U8UA 3G91A 5DV4A 5DFHA 4QH9A 5INQA 1NTFA 2JC4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A7I A;  3W2Y A;  3FZI A;  4B5J A;  4FPV A;  3G38 A;  4LND A;  5J3S A;  4A9C A;  3CJC D;  3I5V A;  3G8V A;  4F1H B;  1VYB A;  5INO A;  4B5I A;  3I41 A;  4L1Y A;  1E9N A;  2A42 B;  4F1I A;  4PUQ A;  3NGO A;  3I48 A;  3W2X A;  2F1N A;  5J42 A;  4CML A;  4GYZ A;  3G0A A;  3NR8 A;  4JG3 A;  3G1K A;  5J8N A;  2A40 B;  1SI6 X;  2EI9 A;  3W3D B;  4RUW A;  4C1R A;  2A3Z B;  3DNI A;  1BIX A;  2JC5 A;  2D1K B;  1I9Z A;  5DG0 A;  3G6S A;  4QHE A;  1ZWX A;  1ATN D;  5INM A;  2V0R A;  3L1W A;  4AWN A;  2UYR X;  5J3Z A;  1DE9 A;  4L1Z A;  3I46 A;  4GZ0 A;  3G4T A;  1SR4 B;  2IMQ X;  2ISI A;  3NGN A;  5CFE A;  3G0R A;  3G3C A;  4B5F A;  3GA6 A;  2DNJ A;  4F1R A;  4B5G A;  2V0S A;  2O3C A;  3N9V A;  5DV2 A;  4QHD A;  3G00 A;  5INN A;  2J63 A;  1DE8 A;  4FVA A;  2A41 B;  2XSW A;  5INP A;  2VOA A;  4CMN A;  1I9Y A;  4K6L F;  1WDU A;  1Y21 A;  2O3H A;  5A7J A;  4IEM A;  5INK A;  3G2C A;  3MTC A;  5DFJ A;  4F1H A;  3G3Y A;  5J3P A;  2DDS A;  2DDR A;  4L20 A;  2F2F B;  2DDT A;  4GZ1 A;  3WCX A;  4GZ2 A;  1DEW A;  4B5H A;  3G2D A;  5CFG A;  3TEB A;  5INL A;  1YJH A;  1AKO A;  3MPR A;  1HD7 A;  3K55 A;  4GEW A;  5DFF A;  3NGQ A;  5HT2 A;  4L21 A;  5DFI A;  1DNK A;  5EWT A;  4B5M A;  3U8U A;  3G91 A;  5DV4 A;  5DFH A;  4QH9 A;  5INQ A;  1NTF A;  2JC4 A; 
#chains in the Genus database with same CATH topology
 5A7I A;  3W2Y A;  3FZI A;  4B5J A;  4FPV A;  3G38 A;  4LND A;  5J3S A;  4A9C A;  3CJC D;  3I5V A;  3G8V A;  4F1H B;  1VYB A;  5INO A;  4B5I A;  3I41 A;  4L1Y A;  1E9N A;  2A42 B;  4F1I A;  4PUQ A;  3NGO A;  3I48 A;  3W2X A;  2F1N A;  5J42 A;  4CML A;  4GYZ A;  3G0A A;  3NR8 A;  4JG3 A;  3G1K A;  5J8N A;  2A40 B;  1SI6 X;  2EI9 A;  3W3D B;  4RUW A;  4C1R A;  2A3Z B;  3DNI A;  1BIX A;  2JC5 A;  2D1K B;  1I9Z A;  5DG0 A;  3G6S A;  4QHE A;  1ZWX A;  1ATN D;  5INM A;  2V0R A;  3L1W A;  4AWN A;  2UYR X;  5J3Z A;  1DE9 A;  4L1Z A;  3I46 A;  4GZ0 A;  3G4T A;  1SR4 B;  2IMQ X;  2ISI A;  3NGN A;  5CFE A;  3G0R A;  3G3C A;  4B5F A;  3GA6 A;  2DNJ A;  4F1R A;  4B5G A;  2V0S A;  2O3C A;  3N9V A;  5DV2 A;  4QHD A;  3G00 A;  5INN A;  2J63 A;  1DE8 A;  4FVA A;  2A41 B;  2XSW A;  5INP A;  2VOA A;  4CMN A;  1I9Y A;  4K6L F;  1WDU A;  1Y21 A;  2O3H A;  5A7J A;  4IEM A;  5INK A;  3G2C A;  3MTC A;  5DFJ A;  4F1H A;  3G3Y A;  5J3P A;  2DDS A;  2DDR A;  4L20 A;  2F2F B;  2DDT A;  4GZ1 A;  3WCX A;  4GZ2 A;  1DEW A;  4B5H A;  3G2D A;  5CFG A;  3TEB A;  5INL A;  1YJH A;  1AKO A;  3MPR A;  1HD7 A;  3K55 A;  4GEW A;  5DFF A;  3NGQ A;  5HT2 A;  4L21 A;  5DFI A;  1DNK A;  5EWT A;  4B5M A;  3U8U A;  3G91 A;  5DV4 A;  5DFH A;  4QH9 A;  5INQ A;  1NTF A;  2JC4 A; 
#chains in the Genus database with same CATH homology
 5A7I A;  3W2Y A;  3FZI A;  4B5J A;  4FPV A;  3G38 A;  4LND A;  5J3S A;  4A9C A;  3CJC D;  3I5V A;  3G8V A;  4F1H B;  1VYB A;  5INO A;  4B5I A;  3I41 A;  4L1Y A;  1E9N A;  2A42 B;  4F1I A;  4PUQ A;  3NGO A;  3I48 A;  3W2X A;  2F1N A;  5J42 A;  4CML A;  4GYZ A;  3G0A A;  3NR8 A;  4JG3 A;  3G1K A;  5J8N A;  2A40 B;  1SI6 X;  2EI9 A;  3W3D B;  4RUW A;  4C1R A;  2A3Z B;  3DNI A;  1BIX A;  2JC5 A;  2D1K B;  1I9Z A;  5DG0 A;  3G6S A;  4QHE A;  1ZWX A;  1ATN D;  5INM A;  2V0R A;  3L1W A;  4AWN A;  2UYR X;  5J3Z A;  1DE9 A;  4L1Z A;  3I46 A;  4GZ0 A;  3G4T A;  1SR4 B;  2IMQ X;  2ISI A;  3NGN A;  5CFE A;  3G0R A;  3G3C A;  4B5F A;  3GA6 A;  2DNJ A;  4F1R A;  4B5G A;  2V0S A;  2O3C A;  3N9V A;  5DV2 A;  4QHD A;  3G00 A;  5INN A;  2J63 A;  1DE8 A;  4FVA A;  2A41 B;  2XSW A;  5INP A;  2VOA A;  4CMN A;  1I9Y A;  4K6L F;  1WDU A;  1Y21 A;  2O3H A;  5A7J A;  4IEM A;  5INK A;  3G2C A;  3MTC A;  5DFJ A;  4F1H A;  3G3Y A;  5J3P A;  2DDS A;  2DDR A;  4L20 A;  2F2F B;  2DDT A;  4GZ1 A;  3WCX A;  4GZ2 A;  1DEW A;  4B5H A;  3G2D A;  5CFG A;  3TEB A;  5INL A;  1YJH A;  1AKO A;  3MPR A;  1HD7 A;  3K55 A;  4GEW A;  5DFF A;  3NGQ A;  5HT2 A;  4L21 A;  5DFI A;  1DNK A;  5EWT A;  4B5M A;  3U8U A;  3G91 A;  5DV4 A;  5DFH A;  4QH9 A;  5INQ A;  1NTF A;  2JC4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...