3NVVC

Crystal structure of bovine xanthine oxidase in complex with arsenite
Total Genus 260
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
260
sequence length
755
structure length
755
Chain Sequence
b'DTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNC'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xanthine dehydrogenase/oxidase
publication title X-ray Crystal Structure of Arsenite-Inhibited Xanthine Oxidase: Mu-Sulfido,Mu-Oxo Double Bridge between Molybdenum and Arsenic in the Active Site.
pubmed doi rcsb
molecule tags Oxidoreductase
total genus 260
structure length 755
sequence length 755
chains with identical sequence L
ec nomenclature ec 1.17.1.4: Xanthine dehydrogenase.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01315 Ald_Xan_dh_C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
C PF02738 Ald_Xan_dh_C2 Molybdopterin-binding domain of aldehyde dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvvC02
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvvC05
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvvC04
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvvC03
3.90.1170.50 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead 3nvvC01
3HRDA 2W55B 3NS1C 3AMZA 1N62B 1JROB 3NVWC 2E3TA 4US9A 1N61B 4USAA 1SIJA 3HRDB 3AM9A 3NVVC 4US8A 1N63B 3ETRC 3NVZC 1SB3A 1DGJA 2W3SB 1JRPB 1N5XA 1N60B 3NVYC 3SR6C 1FIQC 3EUB4 1FFUB 4ZOHA 2W3RB 3NRZC 4C7ZA 3AN1A 1RM6A 3B9JC 3FC4A 1FO4A 1FFVB 4C7YA 3FAHA 1WYGA 1V97A 1N5WB 2W54B 1VDVA 1VLBA 3L4PA 4C80A 1ZXIB
chains in the Genus database with same CATH superfamily
5DM6J 3C2EA 3I55H 1FMAE 3DLLJ 3AMZA 1N62B 5JVHJ 3NVWC 3WO1A 1Q82J 1VQMH 3HRDB 1YIJH 1AZYA 5HL7J 1QVGH 1UOUA 2W3SB 5AN9F 2OTJH 2QEXH 3WO0A 3NVYC 2WK5A 1VQ7H 3PAJA 3EUB4 4GA4A 1YJ9H 3C2VA 4YYYA 1Q86J 4C7ZA 1VQ9H 1BRWA 1K9MJ 1VQLH 4KWVA 1YJWH 5GAEN 5EP8A 2W54B 5H1SO 3GNNA 1YITH 1VQ6H 3TQVA 2W55B 3NS1C 2QIEA 1QPNA 3C2FA 1QAPA 4WFBJ 1NVJA 5GAHN 5DM7J 3CMEH 5EY3A 1NJIJ 2ZJPJ 4US8A 3G71H 1N63B 5AYXA 4WFAJ 1JRPB 1N8RJ 1K73J 3L0GA 2B7NA 1WKIA 4IOCJ 2I1OA 1VQ4H 3CCUH 4X46A 5MPOC 3C2RA 3CCEH 5JVGJ 1M90J 1VQPH 1YTEA 1QVFH 4IOAJ 3NRZC 2B7PA 3AN1A 1VQ8H 3FC4A 3B9JC 3BIIE 1FFVB 4C7YA 4LHMA 2I14A 5MLCO 1VDVA 1NVIE 1T3QB 3CMAH 1YTKA 2PA2A 1N61B 3CCSH 4USAA 3PIOJ 2JBMA 3WNZA 1VQKH 4WF9J 3ETRC 3CCVH 2OTLH 1SB3A 1Y69K 3J7ZM 1YHQH 1Q81J 3G4SH 2QA4H 1QPQA 1JJ2H 1FM0E 3CD6H 3CCMH 1VQNH 2DSJA 2OMDA 1KD1J 4GA5A 4GA6A 1X1OA 3CC4H 1FFUB 1S72H 5GAGN 3CPWH 3CC2H 1KC8J 2TPTA 3H5QA 4XR5A 5AYZA 3RPFA 3PIPJ 1WYGA 2B7QA 1V97A 1W2BH 3CC7H 4I9AA 3CF5J 5GADN 4EADA 3CCJH 4ZOHA 4C80A 1ZXIB 1QPOA 3HRDA 3C2OA 1YJNH 3OW2H 4YEKA 5HUPA 1JROB 4US9A 2E3TA 3VMMA 2WP4A 2J0FA 1SIJA 3NVVC 3AM9A 1QPRA 3G6EH 3NVZC 3CCQH 1K8AJ 1VQOH 4KWWA 1DGJA 4IO9J 1YTDA 1VQ5H 2ZJRJ 1N5XA 1N60B 4EAFA 3SR6C 5HUOA 1OTPA 1FIQC 4WFNJ 3I56H 3CCRH 2WK6A 2ZJQJ 4WCEJ 1M1KJ 5HULA 1O4UA 2W3RB 1RM6A 1YI2H 3CXCH 3CCLH 1FO4A 1Q7YJ 4AP8A 3FAHA 1KQSH 1N5WB 4U67J 5AYYA 1VLBA 3L4PA 4UY8M 2Q5WE
chains in the Genus database with same CATH topology
3HRDA 2W55B 3NS1C 3AMZA 1N62B 1JROB 3NVWC 2E3TA 4US9A 1N61B 4USAA 1SIJA 3HRDB 3AM9A 3NVVC 4US8A 1N63B 3ETRC 3NVZC 1SB3A 1DGJA 2W3SB 1JRPB 1N5XA 1N60B 3NVYC 3SR6C 1FIQC 3EUB4 1FFUB 4ZOHA 2W3RB 3NRZC 4C7ZA 3AN1A 1RM6A 3B9JC 3FC4A 1FO4A 1FFVB 4C7YA 3FAHA 1WYGA 1V97A 1N5WB 2W54B 1VDVA 1VLBA 3L4PA 4C80A 1ZXIB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HRD A;  2W55 B;  3NS1 C;  3AMZ A;  1N62 B;  1JRO B;  3NVW C;  2E3T A;  4US9 A;  1N61 B;  4USA A;  1SIJ A;  3HRD B;  3AM9 A;  3NVV C;  4US8 A;  1N63 B;  3ETR C;  3NVZ C;  1SB3 A;  1DGJ A;  2W3S B;  1JRP B;  1N5X A;  1N60 B;  3NVY C;  3SR6 C;  1FIQ C;  3EUB 4;  1FFU B;  4ZOH A;  2W3R B;  3NRZ C;  4C7Z A;  3AN1 A;  1RM6 A;  3B9J C;  3FC4 A;  1FO4 A;  1FFV B;  4C7Y A;  3FAH A;  1WYG A;  1V97 A;  1N5W B;  2W54 B;  1VDV A;  1VLB A;  3L4P A;  4C80 A;  1ZXI B; 
#chains in the Genus database with same CATH topology
 5DM6 J;  3C2E A;  3I55 H;  1FMA E;  3DLL J;  3AMZ A;  1N62 B;  5JVH J;  3NVW C;  3WO1 A;  1Q82 J;  1VQM H;  3HRD B;  1YIJ H;  1AZY A;  5HL7 J;  1QVG H;  1UOU A;  2W3S B;  5AN9 F;  2OTJ H;  2QEX H;  3WO0 A;  3NVY C;  2WK5 A;  1VQ7 H;  3PAJ A;  3EUB 4;  4GA4 A;  1YJ9 H;  3C2V A;  4YYY A;  1Q86 J;  4C7Z A;  1VQ9 H;  1BRW A;  1K9M J;  1VQL H;  4KWV A;  1YJW H;  5GAE N;  5EP8 A;  2W54 B;  5H1S O;  3GNN A;  1YIT H;  1VQ6 H;  3TQV A;  2W55 B;  3NS1 C;  2QIE A;  1QPN A;  3C2F A;  1QAP A;  4WFB J;  1NVJ A;  5GAH N;  5DM7 J;  3CME H;  5EY3 A;  1NJI J;  2ZJP J;  4US8 A;  3G71 H;  1N63 B;  5AYX A;  4WFA J;  1JRP B;  1N8R J;  1K73 J;  3L0G A;  2B7N A;  1WKI A;  4IOC J;  2I1O A;  1VQ4 H;  3CCU H;  4X46 A;  5MPO C;  3C2R A;  3CCE H;  5JVG J;  1M90 J;  1VQP H;  1YTE A;  1QVF H;  4IOA J;  3NRZ C;  2B7P A;  3AN1 A;  1VQ8 H;  3FC4 A;  3B9J C;  3BII E;  1FFV B;  4C7Y A;  4LHM A;  2I14 A;  5MLC O;  1VDV A;  1NVI E;  1T3Q B;  3CMA H;  1YTK A;  2PA2 A;  1N61 B;  3CCS H;  4USA A;  3PIO J;  2JBM A;  3WNZ A;  1VQK H;  4WF9 J;  3ETR C;  3CCV H;  2OTL H;  1SB3 A;  1Y69 K;  3J7Z M;  1YHQ H;  1Q81 J;  3G4S H;  2QA4 H;  1QPQ A;  1JJ2 H;  1FM0 E;  3CD6 H;  3CCM H;  1VQN H;  2DSJ A;  2OMD A;  1KD1 J;  4GA5 A;  4GA6 A;  1X1O A;  3CC4 H;  1FFU B;  1S72 H;  5GAG N;  3CPW H;  3CC2 H;  1KC8 J;  2TPT A;  3H5Q A;  4XR5 A;  5AYZ A;  3RPF A;  3PIP J;  1WYG A;  2B7Q A;  1V97 A;  1W2B H;  3CC7 H;  4I9A A;  3CF5 J;  5GAD N;  4EAD A;  3CCJ H;  4ZOH A;  4C80 A;  1ZXI B;  1QPO A;  3HRD A;  3C2O A;  1YJN H;  3OW2 H;  4YEK A;  5HUP A;  1JRO B;  4US9 A;  2E3T A;  3VMM A;  2WP4 A;  2J0F A;  1SIJ A;  3NVV C;  3AM9 A;  1QPR A;  3G6E H;  3NVZ C;  3CCQ H;  1K8A J;  1VQO H;  4KWW A;  1DGJ A;  4IO9 J;  1YTD A;  1VQ5 H;  2ZJR J;  1N5X A;  1N60 B;  4EAF A;  3SR6 C;  5HUO A;  1OTP A;  1FIQ C;  4WFN J;  3I56 H;  3CCR H;  2WK6 A;  2ZJQ J;  4WCE J;  1M1K J;  5HUL A;  1O4U A;  2W3R B;  1RM6 A;  1YI2 H;  3CXC H;  3CCL H;  1FO4 A;  1Q7Y J;  4AP8 A;  3FAH A;  1KQS H;  1N5W B;  4U67 J;  5AYY A;  1VLB A;  3L4P A;  4UY8 M;  2Q5W E; 
#chains in the Genus database with same CATH homology
 3HRD A;  2W55 B;  3NS1 C;  3AMZ A;  1N62 B;  1JRO B;  3NVW C;  2E3T A;  4US9 A;  1N61 B;  4USA A;  1SIJ A;  3HRD B;  3AM9 A;  3NVV C;  4US8 A;  1N63 B;  3ETR C;  3NVZ C;  1SB3 A;  1DGJ A;  2W3S B;  1JRP B;  1N5X A;  1N60 B;  3NVY C;  3SR6 C;  1FIQ C;  3EUB 4;  1FFU B;  4ZOH A;  2W3R B;  3NRZ C;  4C7Z A;  3AN1 A;  1RM6 A;  3B9J C;  3FC4 A;  1FO4 A;  1FFV B;  4C7Y A;  3FAH A;  1WYG A;  1V97 A;  1N5W B;  2W54 B;  1VDV A;  1VLB A;  3L4P A;  4C80 A;  1ZXI B; 
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similar chains in the pdb database (?% sequence similarity)

 
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