3NYHA

Crystal structure of lactoperoxidase complexed simultaneously with thiocyanate ion, iodide ion, bromide ion, chloride ion through the substrate diffusion channel reveals a preferential queue of the inorganic substrates towards the distal heme cavity
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of lactoperoxidase complexed simultaneously with thiocyanate ion, iodide ion, bromide ion, chloride ion through the substrate diffusion channel reveals a preferential queue of the inorganic substrates towards the distal heme cavity
rcsb
molecule keywords Lactoperoxidase
molecule tags Oxidoreductase
total genus 194
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2010-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 3nyhA00
1DDXA 1PGEA 1HT5A 3OLUA 4PH9A 3N8ZA 3ERHA 1CVUA 3PY4A 3QF1A 3N8VA 2PUMA 2Z5ZA 5COXA 3Q7DA 4QJQA 1MHLC 3RR3A 1PRHA 3LN1A 1EBVA 1EQHA 1CQEA 3NTBA 2IPSA 1EQGA 4E1GA 4N7AA 3OLTA 2EFBA 3TGYA 3GC1A 5F19A 2OJVA 3TZIA 4NJBA 3N8YA 1FE2A 3N8XA 3NAKA 1CX2A 5IKRA 4M11A 4C1MC 5JVZA 4PNXA 4IG5A 3R5QA 1PTHA 5GLSA 2GJMA 3KRQA 3N8FA 2QRBA 5IKTA 6COXA 3S4FA 5IKVA 1IGZA 3HS6A 5JVYA 3N8YB 2R5LA 4RRXA 2EHAA 3HS5A 1U67A 1CXPC 1D2VC 1PXXA 1MYPC 3GCKA 2OYEP 4RUTA 3MDLA 4OTJA 4Y55A 3NIUA 1DNUC 3NT1A 5IKQA 4KVJA 4GM7A 2QQTA 4MSFA 4RRYA 5FIWC 4GN6A 4RS0A 1DNWC 3FNLA 3F9PC 2E9EA 1Q4GA 3FAQA 5FDQA 4QYQA 4OEKA 3BXIA 3R4XA 3Q9KA 1D5LC 4LJJA 4OTYA 4M10A 3QMOA 4HHSA 1IGXA 4KVKA 4NT3A 4KSZA 3QH0A 3RKEA 3SXVA 4COXA 1D7WC 2QPKA 3N8WA 2OYUP 3GCLA 5JW1A 4KVLA 2IKCA 2NQXA 5KIRA 3MQEA 3UBAA 3NTGA 5B72A 3KK6A 3V6QA 4O1ZA 3GCJA 3R55A 3N8WB 2AYLA 3HS7A 2PT3A 5FF1A 5HPWA 1DIYA 3ERIA 5GH0A 4HHRA 4FM5A 2O86A 3ZS0C 3NYHA 1HT8A 4RRZA 3LN0A 3R5OA 3PGHA 4RRWA 5F1AA 3KRKA 3QL6A 3OGWA 3ZS1C 4Z0LA 4DL1C 3I6NA
chains in the Genus database with same CATH superfamily
1DDXA 1PGEA 1HT5A 3OLUA 4PH9A 3N8ZA 3ERHA 1CVUA 3PY4A 3QF1A 3N8VA 2PUMA 2Z5ZA 5COXA 3Q7DA 4QJQA 1MHLC 3RR3A 1PRHA 3LN1A 1EBVA 1EQHA 1CQEA 3NTBA 2IPSA 1EQGA 4E1GA 4N7AA 3OLTA 2EFBA 3TGYA 3GC1A 5F19A 2OJVA 3TZIA 4NJBA 3N8YA 1FE2A 3N8XA 3NAKA 1CX2A 5IKRA 4M11A 4C1MC 5JVZA 4PNXA 4IG5A 3R5QA 1PTHA 5GLSA 2GJMA 3KRQA 3N8FA 2QRBA 5IKTA 6COXA 3S4FA 5IKVA 1IGZA 3HS6A 5JVYA 3N8YB 2R5LA 4RRXA 2EHAA 3HS5A 1U67A 1CXPC 1D2VC 1PXXA 1MYPC 3GCKA 2OYEP 4RUTA 3MDLA 4OTJA 4Y55A 3NIUA 1DNUC 3NT1A 5IKQA 4KVJA 4GM7A 2QQTA 4MSFA 4RRYA 5FIWC 4GN6A 4RS0A 1DNWC 3FNLA 3F9PC 2E9EA 1Q4GA 3FAQA 5FDQA 4QYQA 4OEKA 3BXIA 3R4XA 3Q9KA 1D5LC 4LJJA 4OTYA 4M10A 3QMOA 4HHSA 1IGXA 4KVKA 4NT3A 4KSZA 3QH0A 3RKEA 3SXVA 4COXA 1D7WC 2QPKA 3N8WA 2OYUP 3GCLA 5JW1A 4KVLA 2IKCA 2NQXA 5KIRA 3MQEA 3UBAA 3NTGA 5B72A 3KK6A 3V6QA 4O1ZA 3GCJA 3R55A 3N8WB 2AYLA 3HS7A 2PT3A 5FF1A 5HPWA 1DIYA 3ERIA 5GH0A 4HHRA 4FM5A 2O86A 3ZS0C 3NYHA 1HT8A 4RRZA 3LN0A 3R5OA 3PGHA 4RRWA 5F1AA 3KRKA 3QL6A 3OGWA 3ZS1C 4Z0LA 4DL1C 3I6NA
chains in the Genus database with same CATH topology
1DDXA 1PGEA 1HT5A 3OLUA 4PH9A 3N8ZA 3ERHA 1CVUA 3PY4A 3QF1A 3N8VA 2PUMA 2Z5ZA 5COXA 3Q7DA 4QJQA 1MHLC 3RR3A 1PRHA 3LN1A 1EBVA 1EQHA 1CQEA 3NTBA 2IPSA 1EQGA 4E1GA 4N7AA 3OLTA 2EFBA 3TGYA 3GC1A 5F19A 2OJVA 3TZIA 4NJBA 3N8YA 1FE2A 3N8XA 3NAKA 1CX2A 5IKRA 4M11A 4C1MC 5JVZA 4PNXA 4IG5A 3R5QA 1PTHA 5GLSA 2GJMA 3KRQA 3N8FA 2QRBA 5IKTA 6COXA 3S4FA 5IKVA 1IGZA 3HS6A 5JVYA 3N8YB 2R5LA 4RRXA 2EHAA 3HS5A 1U67A 1CXPC 1D2VC 1PXXA 1MYPC 3GCKA 2OYEP 4RUTA 3MDLA 4OTJA 4Y55A 3NIUA 1DNUC 3NT1A 5IKQA 4KVJA 4GM7A 2QQTA 4MSFA 4RRYA 5FIWC 4GN6A 4RS0A 1DNWC 3FNLA 3F9PC 2E9EA 1Q4GA 3FAQA 5FDQA 4QYQA 4OEKA 3BXIA 3R4XA 3Q9KA 1D5LC 4LJJA 4OTYA 4M10A 3QMOA 4HHSA 1IGXA 4KVKA 4NT3A 4KSZA 3QH0A 3RKEA 3SXVA 4COXA 1D7WC 2QPKA 3N8WA 2OYUP 3GCLA 5JW1A 4KVLA 2IKCA 2NQXA 5KIRA 3MQEA 3UBAA 3NTGA 5B72A 3KK6A 3V6QA 4O1ZA 3GCJA 3R55A 3N8WB 2AYLA 3HS7A 2PT3A 5FF1A 5HPWA 1DIYA 3ERIA 5GH0A 4HHRA 4FM5A 2O86A 3ZS0C 3NYHA 1HT8A 4RRZA 3LN0A 3R5OA 3PGHA 4RRWA 5F1AA 3KRKA 3QL6A 3OGWA 3ZS1C 4Z0LA 4DL1C 3I6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DDX A;  1PGE A;  1HT5 A;  3OLU A;  4PH9 A;  3N8Z A;  3ERH A;  1CVU A;  3PY4 A;  3QF1 A;  3N8V A;  2PUM A;  2Z5Z A;  5COX A;  3Q7D A;  4QJQ A;  1MHL C;  3RR3 A;  1PRH A;  3LN1 A;  1EBV A;  1EQH A;  1CQE A;  3NTB A;  2IPS A;  1EQG A;  4E1G A;  4N7A A;  3OLT A;  2EFB A;  3TGY A;  3GC1 A;  5F19 A;  2OJV A;  3TZI A;  4NJB A;  3N8Y A;  1FE2 A;  3N8X A;  3NAK A;  1CX2 A;  5IKR A;  4M11 A;  4C1M C;  5JVZ A;  4PNX A;  4IG5 A;  3R5Q A;  1PTH A;  5GLS A;  2GJM A;  3KRQ A;  3N8F A;  2QRB A;  5IKT A;  6COX A;  3S4F A;  5IKV A;  1IGZ A;  3HS6 A;  5JVY A;  3N8Y B;  2R5L A;  4RRX A;  2EHA A;  3HS5 A;  1U67 A;  1CXP C;  1D2V C;  1PXX A;  1MYP C;  3GCK A;  2OYE P;  4RUT A;  3MDL A;  4OTJ A;  4Y55 A;  3NIU A;  1DNU C;  3NT1 A;  5IKQ A;  4KVJ A;  4GM7 A;  2QQT A;  4MSF A;  4RRY A;  5FIW C;  4GN6 A;  4RS0 A;  1DNW C;  3FNL A;  3F9P C;  2E9E A;  1Q4G A;  3FAQ A;  5FDQ A;  4QYQ A;  4OEK A;  3BXI A;  3R4X A;  3Q9K A;  1D5L C;  4LJJ A;  4OTY A;  4M10 A;  3QMO A;  4HHS A;  1IGX A;  4KVK A;  4NT3 A;  4KSZ A;  3QH0 A;  3RKE A;  3SXV A;  4COX A;  1D7W C;  2QPK A;  3N8W A;  2OYU P;  3GCL A;  5JW1 A;  4KVL A;  2IKC A;  2NQX A;  5KIR A;  3MQE A;  3UBA A;  3NTG A;  5B72 A;  3KK6 A;  3V6Q A;  4O1Z A;  3GCJ A;  3R55 A;  3N8W B;  2AYL A;  3HS7 A;  2PT3 A;  5FF1 A;  5HPW A;  1DIY A;  3ERI A;  5GH0 A;  4HHR A;  4FM5 A;  2O86 A;  3ZS0 C;  3NYH A;  1HT8 A;  4RRZ A;  3LN0 A;  3R5O A;  3PGH A;  4RRW A;  5F1A A;  3KRK A;  3QL6 A;  3OGW A;  3ZS1 C;  4Z0L A;  4DL1 C;  3I6N A; 
#chains in the Genus database with same CATH topology
 1DDX A;  1PGE A;  1HT5 A;  3OLU A;  4PH9 A;  3N8Z A;  3ERH A;  1CVU A;  3PY4 A;  3QF1 A;  3N8V A;  2PUM A;  2Z5Z A;  5COX A;  3Q7D A;  4QJQ A;  1MHL C;  3RR3 A;  1PRH A;  3LN1 A;  1EBV A;  1EQH A;  1CQE A;  3NTB A;  2IPS A;  1EQG A;  4E1G A;  4N7A A;  3OLT A;  2EFB A;  3TGY A;  3GC1 A;  5F19 A;  2OJV A;  3TZI A;  4NJB A;  3N8Y A;  1FE2 A;  3N8X A;  3NAK A;  1CX2 A;  5IKR A;  4M11 A;  4C1M C;  5JVZ A;  4PNX A;  4IG5 A;  3R5Q A;  1PTH A;  5GLS A;  2GJM A;  3KRQ A;  3N8F A;  2QRB A;  5IKT A;  6COX A;  3S4F A;  5IKV A;  1IGZ A;  3HS6 A;  5JVY A;  3N8Y B;  2R5L A;  4RRX A;  2EHA A;  3HS5 A;  1U67 A;  1CXP C;  1D2V C;  1PXX A;  1MYP C;  3GCK A;  2OYE P;  4RUT A;  3MDL A;  4OTJ A;  4Y55 A;  3NIU A;  1DNU C;  3NT1 A;  5IKQ A;  4KVJ A;  4GM7 A;  2QQT A;  4MSF A;  4RRY A;  5FIW C;  4GN6 A;  4RS0 A;  1DNW C;  3FNL A;  3F9P C;  2E9E A;  1Q4G A;  3FAQ A;  5FDQ A;  4QYQ A;  4OEK A;  3BXI A;  3R4X A;  3Q9K A;  1D5L C;  4LJJ A;  4OTY A;  4M10 A;  3QMO A;  4HHS A;  1IGX A;  4KVK A;  4NT3 A;  4KSZ A;  3QH0 A;  3RKE A;  3SXV A;  4COX A;  1D7W C;  2QPK A;  3N8W A;  2OYU P;  3GCL A;  5JW1 A;  4KVL A;  2IKC A;  2NQX A;  5KIR A;  3MQE A;  3UBA A;  3NTG A;  5B72 A;  3KK6 A;  3V6Q A;  4O1Z A;  3GCJ A;  3R55 A;  3N8W B;  2AYL A;  3HS7 A;  2PT3 A;  5FF1 A;  5HPW A;  1DIY A;  3ERI A;  5GH0 A;  4HHR A;  4FM5 A;  2O86 A;  3ZS0 C;  3NYH A;  1HT8 A;  4RRZ A;  3LN0 A;  3R5O A;  3PGH A;  4RRW A;  5F1A A;  3KRK A;  3QL6 A;  3OGW A;  3ZS1 C;  4Z0L A;  4DL1 C;  3I6N A; 
#chains in the Genus database with same CATH homology
 1DDX A;  1PGE A;  1HT5 A;  3OLU A;  4PH9 A;  3N8Z A;  3ERH A;  1CVU A;  3PY4 A;  3QF1 A;  3N8V A;  2PUM A;  2Z5Z A;  5COX A;  3Q7D A;  4QJQ A;  1MHL C;  3RR3 A;  1PRH A;  3LN1 A;  1EBV A;  1EQH A;  1CQE A;  3NTB A;  2IPS A;  1EQG A;  4E1G A;  4N7A A;  3OLT A;  2EFB A;  3TGY A;  3GC1 A;  5F19 A;  2OJV A;  3TZI A;  4NJB A;  3N8Y A;  1FE2 A;  3N8X A;  3NAK A;  1CX2 A;  5IKR A;  4M11 A;  4C1M C;  5JVZ A;  4PNX A;  4IG5 A;  3R5Q A;  1PTH A;  5GLS A;  2GJM A;  3KRQ A;  3N8F A;  2QRB A;  5IKT A;  6COX A;  3S4F A;  5IKV A;  1IGZ A;  3HS6 A;  5JVY A;  3N8Y B;  2R5L A;  4RRX A;  2EHA A;  3HS5 A;  1U67 A;  1CXP C;  1D2V C;  1PXX A;  1MYP C;  3GCK A;  2OYE P;  4RUT A;  3MDL A;  4OTJ A;  4Y55 A;  3NIU A;  1DNU C;  3NT1 A;  5IKQ A;  4KVJ A;  4GM7 A;  2QQT A;  4MSF A;  4RRY A;  5FIW C;  4GN6 A;  4RS0 A;  1DNW C;  3FNL A;  3F9P C;  2E9E A;  1Q4G A;  3FAQ A;  5FDQ A;  4QYQ A;  4OEK A;  3BXI A;  3R4X A;  3Q9K A;  1D5L C;  4LJJ A;  4OTY A;  4M10 A;  3QMO A;  4HHS A;  1IGX A;  4KVK A;  4NT3 A;  4KSZ A;  3QH0 A;  3RKE A;  3SXV A;  4COX A;  1D7W C;  2QPK A;  3N8W A;  2OYU P;  3GCL A;  5JW1 A;  4KVL A;  2IKC A;  2NQX A;  5KIR A;  3MQE A;  3UBA A;  3NTG A;  5B72 A;  3KK6 A;  3V6Q A;  4O1Z A;  3GCJ A;  3R55 A;  3N8W B;  2AYL A;  3HS7 A;  2PT3 A;  5FF1 A;  5HPW A;  1DIY A;  3ERI A;  5GH0 A;  4HHR A;  4FM5 A;  2O86 A;  3ZS0 C;  3NYH A;  1HT8 A;  4RRZ A;  3LN0 A;  3R5O A;  3PGH A;  4RRW A;  5F1A A;  3KRK A;  3QL6 A;  3OGW A;  3ZS1 C;  4Z0L A;  4DL1 C;  3I6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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