3NZDA

Structural analysis of pneumocystis carinii and human dhfr complexes with nadph and a series of five 5-(omega-carboxy(alkyloxy(pyrido[2,3-d]pyrimidine derivatives
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-([omega]-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
total genus 59
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3nzdA00
4DP3A 1DRHA 2BL9A 3FY9X 4H98A 1RA3A 1DR5A 4KJJA 2DRCA 3DAUA 3JW3A 3KGYA 4GH8A 4M7VA 4QI9A 5HT4A 4NX6A 5E8QA 3UM5A 2D0KA 3KFYA 2W9HA 1DR1A 4X5IA 1DG5A 2OBCA 3DG8A 3GHWA 1J3JA 3TQBA 1IA1A 3QYOA 3HBBA 5HVEA 4Q67A 4G8ZX 4FGHA 1OHKA 2W3AA 3JWFA 4I13A 3QLYA 3NZBX 1PD9A 4PTHA 4KAKA 1RX7A 2CIGA 3DRCA 3SH2A 2QK8A 3FRBX 3QL3A 2C2SA 1U72A 1DISA 3SR5X 4DFRA 1M7AA 1DG7A 2G6VA 3CL9A 2ITHA 1VDRA 1DRBA 4XT4A 1SEJA 3NXRA 4KY4A 1VJ3A 4EIZA 1RD7A 3GHCA 1RX3A 3L3RA 2AZNA 1RX5A 3S3VA 4ECKA 1AO8A 3FQCA 4LEKX 1S3VA 3UM6A 4X5GA 4M6LA 3JSUA 2L28A 1DR3A 4P66A 1DDRA 3F0XX 1CZ3A 3K45A 1E26A 4LAGX 5HSRA 3DGAA 3CD2A 1QZFA 3QL0A 1J3IA 2DHFA 3M08A 4X5HA 1DHJA 3RG9A 4DPDA 2ZZAA 4M6KA 1S3UA 4RGCA 4OSGA 1CD2A 3I3RA 3NRRA 1MVSA 5ECXA 2O7PA 4QJZD 1DYRA 4H95A 1DAJA 5U26A 4IXED 2P4GA 1HFPA 3FL8A 3FQ0A 3ROAA 4QLFA 4ELBA 4PSTA 3FRAX 3NXXA 5HT5A 3QG2A 3E0BA 1DIUA 3LG4A 3NXVA 4KM0A 1M78A 1YHOA 3D80A 4HA9A 3FY8X 3SRQX 5CCCA 3EEJA 4XE6X 3F0SX 4QLEA 2ANOA 3EIGA 1IA3A 1S3WA 3NZ6X 3DL6A 3K74A 1KMVA 3FREX 1RA2A 3QFXA 1DYJA 3QLZA 4ELGA 2GD9A 1TDRA 3QLSA 1DRAA 3SAIA 4HOEA 3SGYA 3S7AA 3TQAA 4EIGA 5EAJA 1JUVA 2W9SA 3EEKA 3OCHA 4XECX 3DATA 8DFRA 3F0BX 1RX4A 1RC4A 4XT7A 3QYLA 4HOGA 3CSEA 4XT6A 5JG0X 1RA8A 4ELHA 1MVTA 3NTZA 3FS6A 4OR7A 1KLKA 1RB3A 2OIPA 2CD2A 6DFRA 3QGTA 1ZDRA 3FQZA 3IA4A 2D5NA 4P68A 3FQVA 1DLRA 4KM2A 1DR4A 3TQ9A 1DYHA 3JWKA 3EX8A 3IROA 1DLSA 4KL9A 5DXVA 3K47A 4KEBA 2W9TA 3FRFX 3IRNA 3R33A 5HVBA 3NZ9X 3FQOA 3F0VX 4QHVA 3F8YA 1AI9A 4Q6AA 3VCOA 5U27A 3TD8A 1M79A 4FHBA 5HI6A 1U71A 1DHFA 4TU5X 1DG8A 3FYVX 3F0QX 3NZDA 4KNEA 3ZPGA 5HQZA 1JOLA 1RX8A 3INVA 4X5FA 1DHIA 4I1NA 2BLCA 1AOEA 4H96A 4QJCA 2W3MA 4HA7A 5HUIA 1RA9A 3NXOA 4KJLA 2C2TA 3GYFA 5DFRA 1DR2A 4H97A 2W3VA 4ELEA 1PDBA 3ZPCA 4EILA 3NZCX 1DDSA 3SA1A 3QLWA 3Q1HA 3IRMA 4KLXA 3UM8A 3EEMA 3IX9A 1D1GA 3K2HA 5HPBA 3M09A 4KD7A 2LF1A 1HFRA 3FYWX 4KBNA 3N0HA 3F0UX 3F91A 4NX7A 3JTWA 4Q0DA 2BLAA 4EJ1A 3CLBA 1DRFA 4G95A 2XW7A 4ELFA 2FZJA 1RA1A 3JWMA 4DDRA 1OHJA 3NXTA 5HF2X 3NZAX 1IA4A 1PD8A 4Q0EA 4KYAA 3JW5A 4LAEX 3IA5A 3KJSA 3KY8A 4CD2A 5ECCA 2HXVA 2ANQA 1DREA 3I8AX 3JWCA 3GI2A 4PTJA 3SRSX 3S9UA 7DFRA 4HOFA 3NXYA 2HM9A 3F8ZA 5HQYA 1RB2A 4FGGA 2FZIA 2JYBA 1HFQA 4LAHX 3QLRA 4DPHA 3GHVA 1RX6A 4XRBA 3TQ8A 1RX1A 1RX2A 4IXGX 1LUDA 1RF7A 5HSUA 2H2QA 1RH3A 3D84X 3DFRA 3FL9A 3HJ3A 3DL5A 4P3RA 2FZHA 3RO9A 2KGKA 4KFJA 1BZFA 3FRDX 5HF0X 3SRRX 4M6JA 5JA3A 2W9GA 1J3KA 4PSYA 1RG7A 1LY3A 3SA2A 4X5JA 1JOMA 3QLXA 4QLGA 3SQYX 5CC9A 4PSSA 3FQFA 1DF7A 4M7UA 4P3QA 1DYIA 1IA2A 4XT8A 3JVXA 2W3BA 4XT5A 4M2XA 2INQA 3SRWX 3EELA 1U70A 2HQPA 1DR6A 5FDAA 3OAFA 1BOZA 1S3YA 4KY8A 2B3ZA 3KJRA 2W3WA 1RE7A 4KJKA 4PDJA 3NU0A 1KMSA 1LY4A 4IXFX 2BLBA 1DR7A 1RX9A 4G3MA 3SRUX
chains in the Genus database with same CATH superfamily
4DP3A 1DRHA 2BL9A 3FY9X 4H98A 1RA3A 1DR5A 4KJJA 2DRCA 3DAUA 3JW3A 3KGYA 4GH8A 4M7VA 4QI9A 5HT4A 4NX6A 5E8QA 3UM5A 2D0KA 3KFYA 2W9HA 1DR1A 4X5IA 1DG5A 2OBCA 3DG8A 3GHWA 1J3JA 3TQBA 1IA1A 3QYOA 3HBBA 5HVEA 4Q67A 4G8ZX 4FGHA 1OHKA 2W3AA 3JWFA 4I13A 3QLYA 3NZBX 1PD9A 4PTHA 4KAKA 1RX7A 2CIGA 3DRCA 3SH2A 2QK8A 3FRBX 3QL3A 2C2SA 1U72A 1DISA 3SR5X 4DFRA 1M7AA 1DG7A 2G6VA 3CL9A 2ITHA 1VDRA 1DRBA 4XT4A 1SEJA 3NXRA 4KY4A 1VJ3A 4EIZA 1RD7A 3GHCA 1RX3A 3L3RA 2AZNA 1RX5A 3S3VA 4ECKA 1AO8A 3FQCA 4LEKX 1S3VA 3UM6A 4X5GA 4M6LA 3JSUA 2L28A 1DR3A 4P66A 1DDRA 3F0XX 1CZ3A 3K45A 1E26A 4LAGX 5HSRA 3DGAA 3CD2A 1QZFA 3QL0A 1J3IA 2DHFA 3M08A 4X5HA 1DHJA 3RG9A 4DPDA 2ZZAA 4M6KA 1S3UA 4RGCA 4OSGA 1CD2A 3I3RA 3NRRA 1MVSA 5ECXA 2O7PA 4QJZD 1DYRA 4H95A 1DAJA 5U26A 4IXED 2P4GA 1HFPA 3FL8A 3FQ0A 3ROAA 4QLFA 4ELBA 4PSTA 3FRAX 3NXXA 5HT5A 3QG2A 3E0BA 1DIUA 3LG4A 3NXVA 4KM0A 1M78A 1YHOA 3D80A 4HA9A 3FY8X 3SRQX 5CCCA 3EEJA 4XE6X 3F0SX 4QLEA 2ANOA 3EIGA 1IA3A 1S3WA 3NZ6X 3DL6A 3K74A 1KMVA 3FREX 1RA2A 3QFXA 1DYJA 3QLZA 4ELGA 2GD9A 1TDRA 3QLSA 1DRAA 3SAIA 4HOEA 3SGYA 3S7AA 3TQAA 4EIGA 5EAJA 1JUVA 2W9SA 3EEKA 3OCHA 4XECX 3DATA 8DFRA 3F0BX 1RX4A 1RC4A 4XT7A 3QYLA 4HOGA 3CSEA 4XT6A 5JG0X 1RA8A 4ELHA 1MVTA 3NTZA 3FS6A 4OR7A 1KLKA 1RB3A 2OIPA 2CD2A 6DFRA 3QGTA 1ZDRA 3FQZA 3IA4A 2D5NA 4P68A 3FQVA 1DLRA 4KM2A 1DR4A 3TQ9A 1DYHA 3JWKA 3EX8A 3IROA 1DLSA 4KL9A 5DXVA 3K47A 4KEBA 2W9TA 3FRFX 3IRNA 3R33A 5HVBA 3NZ9X 3FQOA 3F0VX 4QHVA 3F8YA 1AI9A 4Q6AA 3VCOA 5U27A 3TD8A 1M79A 4FHBA 5HI6A 1U71A 1DHFA 4TU5X 1DG8A 3FYVX 3F0QX 3NZDA 4KNEA 3ZPGA 5HQZA 1JOLA 1RX8A 3INVA 4X5FA 1DHIA 4I1NA 2BLCA 1AOEA 4H96A 4QJCA 2W3MA 4HA7A 5HUIA 1RA9A 3NXOA 4KJLA 2C2TA 3GYFA 5DFRA 1DR2A 4H97A 2W3VA 4ELEA 1PDBA 3ZPCA 4EILA 3NZCX 1DDSA 3SA1A 3QLWA 3Q1HA 3IRMA 4KLXA 3UM8A 3EEMA 3IX9A 1D1GA 3K2HA 5HPBA 3M09A 4KD7A 2LF1A 1HFRA 3FYWX 4KBNA 3N0HA 3F0UX 3F91A 4NX7A 3JTWA 4Q0DA 2BLAA 4EJ1A 3CLBA 1DRFA 4G95A 2XW7A 4ELFA 2FZJA 1RA1A 3JWMA 4DDRA 1OHJA 3NXTA 5HF2X 3NZAX 1IA4A 1PD8A 4Q0EA 4KYAA 3JW5A 4LAEX 3IA5A 3KJSA 3KY8A 4CD2A 5ECCA 2HXVA 2ANQA 1DREA 3I8AX 3JWCA 3GI2A 4PTJA 3SRSX 3S9UA 7DFRA 4HOFA 3NXYA 2HM9A 3F8ZA 5HQYA 1RB2A 4FGGA 2FZIA 2JYBA 1HFQA 4LAHX 3QLRA 4DPHA 3GHVA 1RX6A 4XRBA 3TQ8A 1RX1A 1RX2A 4IXGX 1LUDA 1RF7A 5HSUA 2H2QA 1RH3A 3D84X 3DFRA 3FL9A 3HJ3A 3DL5A 4P3RA 2FZHA 3RO9A 2KGKA 4KFJA 1BZFA 3FRDX 5HF0X 3SRRX 4M6JA 5JA3A 2W9GA 1J3KA 4PSYA 1RG7A 1LY3A 3SA2A 4X5JA 1JOMA 3QLXA 4QLGA 3SQYX 5CC9A 4PSSA 3FQFA 1DF7A 4M7UA 4P3QA 1DYIA 1IA2A 4XT8A 3JVXA 2W3BA 4XT5A 4M2XA 2INQA 3SRWX 3EELA 1U70A 2HQPA 1DR6A 5FDAA 3OAFA 1BOZA 1S3YA 4KY8A 2B3ZA 3KJRA 2W3WA 1RE7A 4KJKA 4PDJA 3NU0A 1KMSA 1LY4A 4IXFX 2BLBA 1DR7A 1RX9A 4G3MA 3SRUX
chains in the Genus database with same CATH topology
4DP3A 1DRHA 2BL9A 3FY9X 4H98A 1RA3A 1DR5A 4KJJA 2DRCA 3DAUA 3JW3A 3KGYA 4GH8A 4M7VA 4QI9A 5HT4A 4NX6A 5E8QA 3UM5A 2D0KA 3KFYA 2W9HA 1DR1A 4X5IA 1DG5A 2OBCA 3DG8A 3GHWA 1J3JA 3TQBA 1IA1A 3QYOA 3HBBA 5HVEA 4Q67A 4G8ZX 4FGHA 1OHKA 2W3AA 3JWFA 4I13A 3QLYA 3NZBX 1PD9A 4PTHA 4KAKA 1RX7A 2CIGA 3DRCA 3SH2A 2QK8A 3FRBX 3QL3A 2C2SA 1U72A 1DISA 3SR5X 4DFRA 1M7AA 1DG7A 2G6VA 3CL9A 2ITHA 1VDRA 1DRBA 4XT4A 1SEJA 3NXRA 4KY4A 1VJ3A 4EIZA 1RD7A 3GHCA 1RX3A 3L3RA 2AZNA 1RX5A 3S3VA 4ECKA 1AO8A 3FQCA 4LEKX 1S3VA 3UM6A 4X5GA 4M6LA 3JSUA 2L28A 1DR3A 4P66A 1DDRA 3F0XX 1CZ3A 3K45A 1E26A 4LAGX 5HSRA 3DGAA 3CD2A 1QZFA 3QL0A 1J3IA 2DHFA 3M08A 4X5HA 1DHJA 3RG9A 4DPDA 2ZZAA 4M6KA 1S3UA 4RGCA 4OSGA 1CD2A 3I3RA 3NRRA 1MVSA 5ECXA 2O7PA 4QJZD 1DYRA 4H95A 1DAJA 5U26A 4IXED 2P4GA 1HFPA 3FL8A 3FQ0A 3ROAA 4QLFA 4ELBA 4PSTA 3FRAX 3NXXA 5HT5A 3QG2A 3E0BA 1DIUA 3LG4A 3NXVA 4KM0A 1M78A 1YHOA 3D80A 4HA9A 3FY8X 3SRQX 5CCCA 3EEJA 4XE6X 3F0SX 4QLEA 2ANOA 3EIGA 1IA3A 1S3WA 3NZ6X 3DL6A 3K74A 1KMVA 3FREX 1RA2A 3QFXA 1DYJA 3QLZA 4ELGA 2GD9A 1TDRA 3QLSA 1DRAA 3SAIA 4HOEA 3SGYA 3S7AA 3TQAA 4EIGA 5EAJA 1JUVA 2W9SA 3EEKA 3OCHA 4XECX 3DATA 8DFRA 3F0BX 1RX4A 1RC4A 4XT7A 3QYLA 4HOGA 3CSEA 4XT6A 5JG0X 1RA8A 4ELHA 1MVTA 3NTZA 3FS6A 4OR7A 1KLKA 1RB3A 2OIPA 2CD2A 6DFRA 3QGTA 1ZDRA 3FQZA 3IA4A 2D5NA 4P68A 3FQVA 1DLRA 4KM2A 1DR4A 3TQ9A 1DYHA 3JWKA 3EX8A 3IROA 1DLSA 4KL9A 5DXVA 3K47A 4KEBA 2W9TA 3FRFX 3IRNA 3R33A 5HVBA 3NZ9X 3FQOA 3F0VX 4QHVA 3F8YA 1AI9A 4Q6AA 3VCOA 5U27A 3TD8A 1M79A 4FHBA 5HI6A 1U71A 1DHFA 4TU5X 1DG8A 3FYVX 3F0QX 3NZDA 4KNEA 3ZPGA 5HQZA 1JOLA 1RX8A 3INVA 4X5FA 1DHIA 4I1NA 2BLCA 1AOEA 4H96A 4QJCA 2W3MA 4HA7A 5HUIA 1RA9A 3NXOA 4KJLA 2C2TA 3GYFA 5DFRA 1DR2A 4H97A 2W3VA 4ELEA 1PDBA 3ZPCA 4EILA 3NZCX 1DDSA 3SA1A 3QLWA 3Q1HA 3IRMA 4KLXA 3UM8A 3EEMA 3IX9A 1D1GA 3K2HA 5HPBA 3M09A 4KD7A 2LF1A 1HFRA 3FYWX 4KBNA 3N0HA 3F0UX 3F91A 4NX7A 3JTWA 4Q0DA 2BLAA 4EJ1A 3CLBA 1DRFA 4G95A 2XW7A 4ELFA 2FZJA 1RA1A 3JWMA 4DDRA 1OHJA 3NXTA 5HF2X 3NZAX 1IA4A 1PD8A 4Q0EA 4KYAA 3JW5A 4LAEX 3IA5A 3KJSA 3KY8A 4CD2A 5ECCA 2HXVA 2ANQA 1DREA 3I8AX 3JWCA 3GI2A 4PTJA 3SRSX 3S9UA 7DFRA 4HOFA 3NXYA 2HM9A 3F8ZA 5HQYA 1RB2A 4FGGA 2FZIA 2JYBA 1HFQA 4LAHX 3QLRA 4DPHA 3GHVA 1RX6A 4XRBA 3TQ8A 1RX1A 1RX2A 4IXGX 1LUDA 1RF7A 5HSUA 2H2QA 1RH3A 3D84X 3DFRA 3FL9A 3HJ3A 3DL5A 4P3RA 2FZHA 3RO9A 2KGKA 4KFJA 1BZFA 3FRDX 5HF0X 3SRRX 4M6JA 5JA3A 2W9GA 1J3KA 4PSYA 1RG7A 1LY3A 3SA2A 4X5JA 1JOMA 3QLXA 4QLGA 3SQYX 5CC9A 4PSSA 3FQFA 1DF7A 4M7UA 4P3QA 1DYIA 1IA2A 4XT8A 3JVXA 2W3BA 4XT5A 4M2XA 2INQA 3SRWX 3EELA 1U70A 2HQPA 1DR6A 5FDAA 3OAFA 1BOZA 1S3YA 4KY8A 2B3ZA 3KJRA 2W3WA 1RE7A 4KJKA 4PDJA 3NU0A 1KMSA 1LY4A 4IXFX 2BLBA 1DR7A 1RX9A 4G3MA 3SRUX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DP3 A;  1DRH A;  2BL9 A;  3FY9 X;  4H98 A;  1RA3 A;  1DR5 A;  4KJJ A;  2DRC A;  3DAU A;  3JW3 A;  3KGY A;  4GH8 A;  4M7V A;  4QI9 A;  5HT4 A;  4NX6 A;  5E8Q A;  3UM5 A;  2D0K A;  3KFY A;  2W9H A;  1DR1 A;  4X5I A;  1DG5 A;  2OBC A;  3DG8 A;  3GHW A;  1J3J A;  3TQB A;  1IA1 A;  3QYO A;  3HBB A;  5HVE A;  4Q67 A;  4G8Z X;  4FGH A;  1OHK A;  2W3A A;  3JWF A;  4I13 A;  3QLY A;  3NZB X;  1PD9 A;  4PTH A;  4KAK A;  1RX7 A;  2CIG A;  3DRC A;  3SH2 A;  2QK8 A;  3FRB X;  3QL3 A;  2C2S A;  1U72 A;  1DIS A;  3SR5 X;  4DFR A;  1M7A A;  1DG7 A;  2G6V A;  3CL9 A;  2ITH A;  1VDR A;  1DRB A;  4XT4 A;  1SEJ A;  3NXR A;  4KY4 A;  1VJ3 A;  4EIZ A;  1RD7 A;  3GHC A;  1RX3 A;  3L3R A;  2AZN A;  1RX5 A;  3S3V A;  4ECK A;  1AO8 A;  3FQC A;  4LEK X;  1S3V A;  3UM6 A;  4X5G A;  4M6L A;  3JSU A;  2L28 A;  1DR3 A;  4P66 A;  1DDR A;  3F0X X;  1CZ3 A;  3K45 A;  1E26 A;  4LAG X;  5HSR A;  3DGA A;  3CD2 A;  1QZF A;  3QL0 A;  1J3I A;  2DHF A;  3M08 A;  4X5H A;  1DHJ A;  3RG9 A;  4DPD A;  2ZZA A;  4M6K A;  1S3U A;  4RGC A;  4OSG A;  1CD2 A;  3I3R A;  3NRR A;  1MVS A;  5ECX A;  2O7P A;  4QJZ D;  1DYR A;  4H95 A;  1DAJ A;  5U26 A;  4IXE D;  2P4G A;  1HFP A;  3FL8 A;  3FQ0 A;  3ROA A;  4QLF A;  4ELB A;  4PST A;  3FRA X;  3NXX A;  5HT5 A;  3QG2 A;  3E0B A;  1DIU A;  3LG4 A;  3NXV A;  4KM0 A;  1M78 A;  1YHO A;  3D80 A;  4HA9 A;  3FY8 X;  3SRQ X;  5CCC A;  3EEJ A;  4XE6 X;  3F0S X;  4QLE A;  2ANO A;  3EIG A;  1IA3 A;  1S3W A;  3NZ6 X;  3DL6 A;  3K74 A;  1KMV A;  3FRE X;  1RA2 A;  3QFX A;  1DYJ A;  3QLZ A;  4ELG A;  2GD9 A;  1TDR A;  3QLS A;  1DRA A;  3SAI A;  4HOE A;  3SGY A;  3S7A A;  3TQA A;  4EIG A;  5EAJ A;  1JUV A;  2W9S A;  3EEK A;  3OCH A;  4XEC X;  3DAT A;  8DFR A;  3F0B X;  1RX4 A;  1RC4 A;  4XT7 A;  3QYL A;  4HOG A;  3CSE A;  4XT6 A;  5JG0 X;  1RA8 A;  4ELH A;  1MVT A;  3NTZ A;  3FS6 A;  4OR7 A;  1KLK A;  1RB3 A;  2OIP A;  2CD2 A;  6DFR A;  3QGT A;  1ZDR A;  3FQZ A;  3IA4 A;  2D5N A;  4P68 A;  3FQV A;  1DLR A;  4KM2 A;  1DR4 A;  3TQ9 A;  1DYH A;  3JWK A;  3EX8 A;  3IRO A;  1DLS A;  4KL9 A;  5DXV A;  3K47 A;  4KEB A;  2W9T A;  3FRF X;  3IRN A;  3R33 A;  5HVB A;  3NZ9 X;  3FQO A;  3F0V X;  4QHV A;  3F8Y A;  1AI9 A;  4Q6A A;  3VCO A;  5U27 A;  3TD8 A;  1M79 A;  4FHB A;  5HI6 A;  1U71 A;  1DHF A;  4TU5 X;  1DG8 A;  3FYV X;  3F0Q X;  3NZD A;  4KNE A;  3ZPG A;  5HQZ A;  1JOL A;  1RX8 A;  3INV A;  4X5F A;  1DHI A;  4I1N A;  2BLC A;  1AOE A;  4H96 A;  4QJC A;  2W3M A;  4HA7 A;  5HUI A;  1RA9 A;  3NXO A;  4KJL A;  2C2T A;  3GYF A;  5DFR A;  1DR2 A;  4H97 A;  2W3V A;  4ELE A;  1PDB A;  3ZPC A;  4EIL A;  3NZC X;  1DDS A;  3SA1 A;  3QLW A;  3Q1H A;  3IRM A;  4KLX A;  3UM8 A;  3EEM A;  3IX9 A;  1D1G A;  3K2H A;  5HPB A;  3M09 A;  4KD7 A;  2LF1 A;  1HFR A;  3FYW X;  4KBN A;  3N0H A;  3F0U X;  3F91 A;  4NX7 A;  3JTW A;  4Q0D A;  2BLA A;  4EJ1 A;  3CLB A;  1DRF A;  4G95 A;  2XW7 A;  4ELF A;  2FZJ A;  1RA1 A;  3JWM A;  4DDR A;  1OHJ A;  3NXT A;  5HF2 X;  3NZA X;  1IA4 A;  1PD8 A;  4Q0E A;  4KYA A;  3JW5 A;  4LAE X;  3IA5 A;  3KJS A;  3KY8 A;  4CD2 A;  5ECC A;  2HXV A;  2ANQ A;  1DRE A;  3I8A X;  3JWC A;  3GI2 A;  4PTJ A;  3SRS X;  3S9U A;  7DFR A;  4HOF A;  3NXY A;  2HM9 A;  3F8Z A;  5HQY A;  1RB2 A;  4FGG A;  2FZI A;  2JYB A;  1HFQ A;  4LAH X;  3QLR A;  4DPH A;  3GHV A;  1RX6 A;  4XRB A;  3TQ8 A;  1RX1 A;  1RX2 A;  4IXG X;  1LUD A;  1RF7 A;  5HSU A;  2H2Q A;  1RH3 A;  3D84 X;  3DFR A;  3FL9 A;  3HJ3 A;  3DL5 A;  4P3R A;  2FZH A;  3RO9 A;  2KGK A;  4KFJ A;  1BZF A;  3FRD X;  5HF0 X;  3SRR X;  4M6J A;  5JA3 A;  2W9G A;  1J3K A;  4PSY A;  1RG7 A;  1LY3 A;  3SA2 A;  4X5J A;  1JOM A;  3QLX A;  4QLG A;  3SQY X;  5CC9 A;  4PSS A;  3FQF A;  1DF7 A;  4M7U A;  4P3Q A;  1DYI A;  1IA2 A;  4XT8 A;  3JVX A;  2W3B A;  4XT5 A;  4M2X A;  2INQ A;  3SRW X;  3EEL A;  1U70 A;  2HQP A;  1DR6 A;  5FDA A;  3OAF A;  1BOZ A;  1S3Y A;  4KY8 A;  2B3Z A;  3KJR A;  2W3W A;  1RE7 A;  4KJK A;  4PDJ A;  3NU0 A;  1KMS A;  1LY4 A;  4IXF X;  2BLB A;  1DR7 A;  1RX9 A;  4G3M A;  3SRU X; 
#chains in the Genus database with same CATH topology
 4DP3 A;  1DRH A;  2BL9 A;  3FY9 X;  4H98 A;  1RA3 A;  1DR5 A;  4KJJ A;  2DRC A;  3DAU A;  3JW3 A;  3KGY A;  4GH8 A;  4M7V A;  4QI9 A;  5HT4 A;  4NX6 A;  5E8Q A;  3UM5 A;  2D0K A;  3KFY A;  2W9H A;  1DR1 A;  4X5I A;  1DG5 A;  2OBC A;  3DG8 A;  3GHW A;  1J3J A;  3TQB A;  1IA1 A;  3QYO A;  3HBB A;  5HVE A;  4Q67 A;  4G8Z X;  4FGH A;  1OHK A;  2W3A A;  3JWF A;  4I13 A;  3QLY A;  3NZB X;  1PD9 A;  4PTH A;  4KAK A;  1RX7 A;  2CIG A;  3DRC A;  3SH2 A;  2QK8 A;  3FRB X;  3QL3 A;  2C2S A;  1U72 A;  1DIS A;  3SR5 X;  4DFR A;  1M7A A;  1DG7 A;  2G6V A;  3CL9 A;  2ITH A;  1VDR A;  1DRB A;  4XT4 A;  1SEJ A;  3NXR A;  4KY4 A;  1VJ3 A;  4EIZ A;  1RD7 A;  3GHC A;  1RX3 A;  3L3R A;  2AZN A;  1RX5 A;  3S3V A;  4ECK A;  1AO8 A;  3FQC A;  4LEK X;  1S3V A;  3UM6 A;  4X5G A;  4M6L A;  3JSU A;  2L28 A;  1DR3 A;  4P66 A;  1DDR A;  3F0X X;  1CZ3 A;  3K45 A;  1E26 A;  4LAG X;  5HSR A;  3DGA A;  3CD2 A;  1QZF A;  3QL0 A;  1J3I A;  2DHF A;  3M08 A;  4X5H A;  1DHJ A;  3RG9 A;  4DPD A;  2ZZA A;  4M6K A;  1S3U A;  4RGC A;  4OSG A;  1CD2 A;  3I3R A;  3NRR A;  1MVS A;  5ECX A;  2O7P A;  4QJZ D;  1DYR A;  4H95 A;  1DAJ A;  5U26 A;  4IXE D;  2P4G A;  1HFP A;  3FL8 A;  3FQ0 A;  3ROA A;  4QLF A;  4ELB A;  4PST A;  3FRA X;  3NXX A;  5HT5 A;  3QG2 A;  3E0B A;  1DIU A;  3LG4 A;  3NXV A;  4KM0 A;  1M78 A;  1YHO A;  3D80 A;  4HA9 A;  3FY8 X;  3SRQ X;  5CCC A;  3EEJ A;  4XE6 X;  3F0S X;  4QLE A;  2ANO A;  3EIG A;  1IA3 A;  1S3W A;  3NZ6 X;  3DL6 A;  3K74 A;  1KMV A;  3FRE X;  1RA2 A;  3QFX A;  1DYJ A;  3QLZ A;  4ELG A;  2GD9 A;  1TDR A;  3QLS A;  1DRA A;  3SAI A;  4HOE A;  3SGY A;  3S7A A;  3TQA A;  4EIG A;  5EAJ A;  1JUV A;  2W9S A;  3EEK A;  3OCH A;  4XEC X;  3DAT A;  8DFR A;  3F0B X;  1RX4 A;  1RC4 A;  4XT7 A;  3QYL A;  4HOG A;  3CSE A;  4XT6 A;  5JG0 X;  1RA8 A;  4ELH A;  1MVT A;  3NTZ A;  3FS6 A;  4OR7 A;  1KLK A;  1RB3 A;  2OIP A;  2CD2 A;  6DFR A;  3QGT A;  1ZDR A;  3FQZ A;  3IA4 A;  2D5N A;  4P68 A;  3FQV A;  1DLR A;  4KM2 A;  1DR4 A;  3TQ9 A;  1DYH A;  3JWK A;  3EX8 A;  3IRO A;  1DLS A;  4KL9 A;  5DXV A;  3K47 A;  4KEB A;  2W9T A;  3FRF X;  3IRN A;  3R33 A;  5HVB A;  3NZ9 X;  3FQO A;  3F0V X;  4QHV A;  3F8Y A;  1AI9 A;  4Q6A A;  3VCO A;  5U27 A;  3TD8 A;  1M79 A;  4FHB A;  5HI6 A;  1U71 A;  1DHF A;  4TU5 X;  1DG8 A;  3FYV X;  3F0Q X;  3NZD A;  4KNE A;  3ZPG A;  5HQZ A;  1JOL A;  1RX8 A;  3INV A;  4X5F A;  1DHI A;  4I1N A;  2BLC A;  1AOE A;  4H96 A;  4QJC A;  2W3M A;  4HA7 A;  5HUI A;  1RA9 A;  3NXO A;  4KJL A;  2C2T A;  3GYF A;  5DFR A;  1DR2 A;  4H97 A;  2W3V A;  4ELE A;  1PDB A;  3ZPC A;  4EIL A;  3NZC X;  1DDS A;  3SA1 A;  3QLW A;  3Q1H A;  3IRM A;  4KLX A;  3UM8 A;  3EEM A;  3IX9 A;  1D1G A;  3K2H A;  5HPB A;  3M09 A;  4KD7 A;  2LF1 A;  1HFR A;  3FYW X;  4KBN A;  3N0H A;  3F0U X;  3F91 A;  4NX7 A;  3JTW A;  4Q0D A;  2BLA A;  4EJ1 A;  3CLB A;  1DRF A;  4G95 A;  2XW7 A;  4ELF A;  2FZJ A;  1RA1 A;  3JWM A;  4DDR A;  1OHJ A;  3NXT A;  5HF2 X;  3NZA X;  1IA4 A;  1PD8 A;  4Q0E A;  4KYA A;  3JW5 A;  4LAE X;  3IA5 A;  3KJS A;  3KY8 A;  4CD2 A;  5ECC A;  2HXV A;  2ANQ A;  1DRE A;  3I8A X;  3JWC A;  3GI2 A;  4PTJ A;  3SRS X;  3S9U A;  7DFR A;  4HOF A;  3NXY A;  2HM9 A;  3F8Z A;  5HQY A;  1RB2 A;  4FGG A;  2FZI A;  2JYB A;  1HFQ A;  4LAH X;  3QLR A;  4DPH A;  3GHV A;  1RX6 A;  4XRB A;  3TQ8 A;  1RX1 A;  1RX2 A;  4IXG X;  1LUD A;  1RF7 A;  5HSU A;  2H2Q A;  1RH3 A;  3D84 X;  3DFR A;  3FL9 A;  3HJ3 A;  3DL5 A;  4P3R A;  2FZH A;  3RO9 A;  2KGK A;  4KFJ A;  1BZF A;  3FRD X;  5HF0 X;  3SRR X;  4M6J A;  5JA3 A;  2W9G A;  1J3K A;  4PSY A;  1RG7 A;  1LY3 A;  3SA2 A;  4X5J A;  1JOM A;  3QLX A;  4QLG A;  3SQY X;  5CC9 A;  4PSS A;  3FQF A;  1DF7 A;  4M7U A;  4P3Q A;  1DYI A;  1IA2 A;  4XT8 A;  3JVX A;  2W3B A;  4XT5 A;  4M2X A;  2INQ A;  3SRW X;  3EEL A;  1U70 A;  2HQP A;  1DR6 A;  5FDA A;  3OAF A;  1BOZ A;  1S3Y A;  4KY8 A;  2B3Z A;  3KJR A;  2W3W A;  1RE7 A;  4KJK A;  4PDJ A;  3NU0 A;  1KMS A;  1LY4 A;  4IXF X;  2BLB A;  1DR7 A;  1RX9 A;  4G3M A;  3SRU X; 
#chains in the Genus database with same CATH homology
 4DP3 A;  1DRH A;  2BL9 A;  3FY9 X;  4H98 A;  1RA3 A;  1DR5 A;  4KJJ A;  2DRC A;  3DAU A;  3JW3 A;  3KGY A;  4GH8 A;  4M7V A;  4QI9 A;  5HT4 A;  4NX6 A;  5E8Q A;  3UM5 A;  2D0K A;  3KFY A;  2W9H A;  1DR1 A;  4X5I A;  1DG5 A;  2OBC A;  3DG8 A;  3GHW A;  1J3J A;  3TQB A;  1IA1 A;  3QYO A;  3HBB A;  5HVE A;  4Q67 A;  4G8Z X;  4FGH A;  1OHK A;  2W3A A;  3JWF A;  4I13 A;  3QLY A;  3NZB X;  1PD9 A;  4PTH A;  4KAK A;  1RX7 A;  2CIG A;  3DRC A;  3SH2 A;  2QK8 A;  3FRB X;  3QL3 A;  2C2S A;  1U72 A;  1DIS A;  3SR5 X;  4DFR A;  1M7A A;  1DG7 A;  2G6V A;  3CL9 A;  2ITH A;  1VDR A;  1DRB A;  4XT4 A;  1SEJ A;  3NXR A;  4KY4 A;  1VJ3 A;  4EIZ A;  1RD7 A;  3GHC A;  1RX3 A;  3L3R A;  2AZN A;  1RX5 A;  3S3V A;  4ECK A;  1AO8 A;  3FQC A;  4LEK X;  1S3V A;  3UM6 A;  4X5G A;  4M6L A;  3JSU A;  2L28 A;  1DR3 A;  4P66 A;  1DDR A;  3F0X X;  1CZ3 A;  3K45 A;  1E26 A;  4LAG X;  5HSR A;  3DGA A;  3CD2 A;  1QZF A;  3QL0 A;  1J3I A;  2DHF A;  3M08 A;  4X5H A;  1DHJ A;  3RG9 A;  4DPD A;  2ZZA A;  4M6K A;  1S3U A;  4RGC A;  4OSG A;  1CD2 A;  3I3R A;  3NRR A;  1MVS A;  5ECX A;  2O7P A;  4QJZ D;  1DYR A;  4H95 A;  1DAJ A;  5U26 A;  4IXE D;  2P4G A;  1HFP A;  3FL8 A;  3FQ0 A;  3ROA A;  4QLF A;  4ELB A;  4PST A;  3FRA X;  3NXX A;  5HT5 A;  3QG2 A;  3E0B A;  1DIU A;  3LG4 A;  3NXV A;  4KM0 A;  1M78 A;  1YHO A;  3D80 A;  4HA9 A;  3FY8 X;  3SRQ X;  5CCC A;  3EEJ A;  4XE6 X;  3F0S X;  4QLE A;  2ANO A;  3EIG A;  1IA3 A;  1S3W A;  3NZ6 X;  3DL6 A;  3K74 A;  1KMV A;  3FRE X;  1RA2 A;  3QFX A;  1DYJ A;  3QLZ A;  4ELG A;  2GD9 A;  1TDR A;  3QLS A;  1DRA A;  3SAI A;  4HOE A;  3SGY A;  3S7A A;  3TQA A;  4EIG A;  5EAJ A;  1JUV A;  2W9S A;  3EEK A;  3OCH A;  4XEC X;  3DAT A;  8DFR A;  3F0B X;  1RX4 A;  1RC4 A;  4XT7 A;  3QYL A;  4HOG A;  3CSE A;  4XT6 A;  5JG0 X;  1RA8 A;  4ELH A;  1MVT A;  3NTZ A;  3FS6 A;  4OR7 A;  1KLK A;  1RB3 A;  2OIP A;  2CD2 A;  6DFR A;  3QGT A;  1ZDR A;  3FQZ A;  3IA4 A;  2D5N A;  4P68 A;  3FQV A;  1DLR A;  4KM2 A;  1DR4 A;  3TQ9 A;  1DYH A;  3JWK A;  3EX8 A;  3IRO A;  1DLS A;  4KL9 A;  5DXV A;  3K47 A;  4KEB A;  2W9T A;  3FRF X;  3IRN A;  3R33 A;  5HVB A;  3NZ9 X;  3FQO A;  3F0V X;  4QHV A;  3F8Y A;  1AI9 A;  4Q6A A;  3VCO A;  5U27 A;  3TD8 A;  1M79 A;  4FHB A;  5HI6 A;  1U71 A;  1DHF A;  4TU5 X;  1DG8 A;  3FYV X;  3F0Q X;  3NZD A;  4KNE A;  3ZPG A;  5HQZ A;  1JOL A;  1RX8 A;  3INV A;  4X5F A;  1DHI A;  4I1N A;  2BLC A;  1AOE A;  4H96 A;  4QJC A;  2W3M A;  4HA7 A;  5HUI A;  1RA9 A;  3NXO A;  4KJL A;  2C2T A;  3GYF A;  5DFR A;  1DR2 A;  4H97 A;  2W3V A;  4ELE A;  1PDB A;  3ZPC A;  4EIL A;  3NZC X;  1DDS A;  3SA1 A;  3QLW A;  3Q1H A;  3IRM A;  4KLX A;  3UM8 A;  3EEM A;  3IX9 A;  1D1G A;  3K2H A;  5HPB A;  3M09 A;  4KD7 A;  2LF1 A;  1HFR A;  3FYW X;  4KBN A;  3N0H A;  3F0U X;  3F91 A;  4NX7 A;  3JTW A;  4Q0D A;  2BLA A;  4EJ1 A;  3CLB A;  1DRF A;  4G95 A;  2XW7 A;  4ELF A;  2FZJ A;  1RA1 A;  3JWM A;  4DDR A;  1OHJ A;  3NXT A;  5HF2 X;  3NZA X;  1IA4 A;  1PD8 A;  4Q0E A;  4KYA A;  3JW5 A;  4LAE X;  3IA5 A;  3KJS A;  3KY8 A;  4CD2 A;  5ECC A;  2HXV A;  2ANQ A;  1DRE A;  3I8A X;  3JWC A;  3GI2 A;  4PTJ A;  3SRS X;  3S9U A;  7DFR A;  4HOF A;  3NXY A;  2HM9 A;  3F8Z A;  5HQY A;  1RB2 A;  4FGG A;  2FZI A;  2JYB A;  1HFQ A;  4LAH X;  3QLR A;  4DPH A;  3GHV A;  1RX6 A;  4XRB A;  3TQ8 A;  1RX1 A;  1RX2 A;  4IXG X;  1LUD A;  1RF7 A;  5HSU A;  2H2Q A;  1RH3 A;  3D84 X;  3DFR A;  3FL9 A;  3HJ3 A;  3DL5 A;  4P3R A;  2FZH A;  3RO9 A;  2KGK A;  4KFJ A;  1BZF A;  3FRD X;  5HF0 X;  3SRR X;  4M6J A;  5JA3 A;  2W9G A;  1J3K A;  4PSY A;  1RG7 A;  1LY3 A;  3SA2 A;  4X5J A;  1JOM A;  3QLX A;  4QLG A;  3SQY X;  5CC9 A;  4PSS A;  3FQF A;  1DF7 A;  4M7U A;  4P3Q A;  1DYI A;  1IA2 A;  4XT8 A;  3JVX A;  2W3B A;  4XT5 A;  4M2X A;  2INQ A;  3SRW X;  3EEL A;  1U70 A;  2HQP A;  1DR6 A;  5FDA A;  3OAF A;  1BOZ A;  1S3Y A;  4KY8 A;  2B3Z A;  3KJR A;  2W3W A;  1RE7 A;  4KJK A;  4PDJ A;  3NU0 A;  1KMS A;  1LY4 A;  4IXF X;  2BLB A;  1DR7 A;  1RX9 A;  4G3M A;  3SRU X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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