3OIJA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 2 molecules of cognate rna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
Knots found
sequence length
225
structure length
211
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule keywords Essential for mitotic growth 1
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
total genus 62
structure length 211
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oijA01
3IEFA 4YQBA 1X7PA 4YQ5A 4YQCA 2I6DA 1K3RA 4RG1A 1MXIA 4IG6A 4X3LA 4YQQA 4YQ0A 4MCDA 4H3YA 4YQ8A 4MCCA 5GMCA 4YQ4A 1UAKA 2Z0YA 4JAKA 4YQSA 1UAMA 1GZ0A 3NK6A 4YQ2A 4YQPA 4YQTA 3N4KA 3GYQA 3KW2A 4YVKA 3E5YA 1VH0A 4KGNA 4YQJA 1ZJRA 3N4JA 4YPZA 2CX8A 5FAIA 5GMBA 1J85A 2EGVA 3AXZA 2EGWA 4CNEA 4YQIA 1V6ZA 4X3MA 4H3ZA 3OINA 3KNUA 1OY5A 3DCMX 1TO0A 3L8UA 4CNDA 4MCBA 1UAJA 4YQKA 2YY8A 1VHKA 4YQRA 4E8BA 4YQDA 3BBEA 4YQ9A 3NK7A 2QMMA 4CNGA 3BBDA 3AIAA 1O6DA 5GM8A 4YVGA 2HA8A 3ILKA 4J3CA 4YQLA 1NS5A 1V2XA 4YPWA 2O3AA 4YPXA 4FAKA 3IC6A 3BBHA 4YQ6A 1VHYA 4PZKA 3O7BA 4YQOA 4YVIA 3OIIA 1IPAA 4YVHA 5D9FA 1P9PA 1NXZA 1UALA 4JALA 4YQNA 4YPYA 2V3JA 1X7OA 2QWVA 4KDZA 4YQGA 4CNFA 3AI9X 4YQ1A 2V3KA 3KY7A 3QUVA 4YQ7A 4YQ3A 4L69A 4YVJA 3ONPA 1Z85A 3KTYA 4XBOA 5CO4A 4YQAA 3OIJA
chains in the Genus database with same CATH superfamily
3IEFA 4YQBA 1X7PA 4YQ5A 4YQCA 2I6DA 1K3RA 4RG1A 1MXIA 4IG6A 4X3LA 4FMWA 4YQQA 4YQ0A 4MCDA 4H3YA 4YQ8A 4MCCA 5GMCA 4YQ4A 1UAKA 2Z0YA 4JAKA 4YQSA 1UAMA 1GZ0A 3NK6A 4YQ2A 4YQPA 4YQTA 3N4KA 3GYQA 3KW2A 4YVKA 3E5YA 1VH0A 4KGNA 4YQJA 1ZJRA 3N4JA 4JWGA 4YPZA 2CX8A 5FAIA 5GMBA 1J85A 2EGVA 3AXZA 4JWHA 2EGWA 4CNEA 4YQIA 1V6ZA 4X3MA 4H3ZA 3OINA 3KNUA 1OY5A 3DCMX 1TO0A 3L8UA 4CNDA 4MCBA 1UAJA 4YQKA 2YY8A 1VHKA 4YQRA 4E8BA 4YQDA 3BBEA 4YQ9A 3NK7A 2QMMA 4CNGA 3BBDA 3AIAA 1O6DA 5GM8A 4YVGA 2HA8A 3ILKA 4J3CA 4YQLA 1NS5A 1V2XA 4YPWA 2O3AA 4YPXA 4FAKA 3IC6A 3BBHA 4YQ6A 1VHYA 4PZKA 4JWJA 3O7BA 4YQOA 4YVIA 3OIIA 1IPAA 4YVHA 5D9FA 1P9PA 1NXZA 1UALA 4JALA 4YQNA 4YPYA 2V3JA 1X7OA 2QWVA 4KDZA 4YQGA 4CNFA 3AI9X 4YQ1A 2V3KA 3KY7A 3QUVA 4YQ7A 4YQ3A 4L69A 4YVJA 3ONPA 4JWFA 1Z85A 3KTYA 4XBOA 5CO4A 4YQAA 3OIJA
chains in the Genus database with same CATH topology
3IEFA 4YQBA 1X7PA 4YQ5A 4YQCA 2I6DA 1K3RA 4RG1A 1MXIA 4IG6A 4X3LA 4FMWA 4YQQA 4YQ0A 4MCDA 4H3YA 4YQ8A 4MCCA 5GMCA 4YQ4A 1UAKA 2Z0YA 4JAKA 4YQSA 1UAMA 1GZ0A 3NK6A 4YQ2A 4YQPA 4YQTA 3N4KA 3GYQA 3KW2A 4YVKA 3E5YA 1VH0A 4KGNA 4YQJA 1ZJRA 3N4JA 4JWGA 4YPZA 2CX8A 5FAIA 5GMBA 1J85A 2EGVA 3AXZA 4JWHA 2EGWA 4CNEA 4YQIA 1V6ZA 4X3MA 4H3ZA 3OINA 3KNUA 1OY5A 3DCMX 1TO0A 3L8UA 4CNDA 4MCBA 1UAJA 4YQKA 2YY8A 1VHKA 4YQRA 4E8BA 4YQDA 3BBEA 4YQ9A 3NK7A 2QMMA 4CNGA 3BBDA 3AIAA 1O6DA 5GM8A 4YVGA 2HA8A 3ILKA 4J3CA 4YQLA 1NS5A 1V2XA 4YPWA 2O3AA 4YPXA 4FAKA 3IC6A 3BBHA 4YQ6A 1VHYA 4PZKA 4JWJA 3O7BA 4YQOA 4YVIA 3OIIA 1IPAA 4YVHA 5D9FA 1P9PA 1NXZA 1UALA 4JALA 4YQNA 4YPYA 2V3JA 1X7OA 2QWVA 4KDZA 4YQGA 4CNFA 3AI9X 4YQ1A 2V3KA 3KY7A 3QUVA 4YQ7A 4YQ3A 4L69A 4YVJA 3ONPA 4JWFA 1Z85A 3KTYA 4XBOA 5CO4A 4YQAA 3OIJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IEF A;  4YQB A;  1X7P A;  4YQ5 A;  4YQC A;  2I6D A;  1K3R A;  4RG1 A;  1MXI A;  4IG6 A;  4X3L A;  4YQQ A;  4YQ0 A;  4MCD A;  4H3Y A;  4YQ8 A;  4MCC A;  5GMC A;  4YQ4 A;  1UAK A;  2Z0Y A;  4JAK A;  4YQS A;  1UAM A;  1GZ0 A;  3NK6 A;  4YQ2 A;  4YQP A;  4YQT A;  3N4K A;  3GYQ A;  3KW2 A;  4YVK A;  3E5Y A;  1VH0 A;  4KGN A;  4YQJ A;  1ZJR A;  3N4J A;  4YPZ A;  2CX8 A;  5FAI A;  5GMB A;  1J85 A;  2EGV A;  3AXZ A;  2EGW A;  4CNE A;  4YQI A;  1V6Z A;  4X3M A;  4H3Z A;  3OIN A;  3KNU A;  1OY5 A;  3DCM X;  1TO0 A;  3L8U A;  4CND A;  4MCB A;  1UAJ A;  4YQK A;  2YY8 A;  1VHK A;  4YQR A;  4E8B A;  4YQD A;  3BBE A;  4YQ9 A;  3NK7 A;  2QMM A;  4CNG A;  3BBD A;  3AIA A;  1O6D A;  5GM8 A;  4YVG A;  2HA8 A;  3ILK A;  4J3C A;  4YQL A;  1NS5 A;  1V2X A;  4YPW A;  2O3A A;  4YPX A;  4FAK A;  3IC6 A;  3BBH A;  4YQ6 A;  1VHY A;  4PZK A;  3O7B A;  4YQO A;  4YVI A;  3OII A;  1IPA A;  4YVH A;  5D9F A;  1P9P A;  1NXZ A;  1UAL A;  4JAL A;  4YQN A;  4YPY A;  2V3J A;  1X7O A;  2QWV A;  4KDZ A;  4YQG A;  4CNF A;  3AI9 X;  4YQ1 A;  2V3K A;  3KY7 A;  3QUV A;  4YQ7 A;  4YQ3 A;  4L69 A;  4YVJ A;  3ONP A;  1Z85 A;  3KTY A;  4XBO A;  5CO4 A;  4YQA A;  3OIJ A; 
#chains in the Genus database with same CATH topology
 3IEF A;  4YQB A;  1X7P A;  4YQ5 A;  4YQC A;  2I6D A;  1K3R A;  4RG1 A;  1MXI A;  4IG6 A;  4X3L A;  4FMW A;  4YQQ A;  4YQ0 A;  4MCD A;  4H3Y A;  4YQ8 A;  4MCC A;  5GMC A;  4YQ4 A;  1UAK A;  2Z0Y A;  4JAK A;  4YQS A;  1UAM A;  1GZ0 A;  3NK6 A;  4YQ2 A;  4YQP A;  4YQT A;  3N4K A;  3GYQ A;  3KW2 A;  4YVK A;  3E5Y A;  1VH0 A;  4KGN A;  4YQJ A;  1ZJR A;  3N4J A;  4JWG A;  4YPZ A;  2CX8 A;  5FAI A;  5GMB A;  1J85 A;  2EGV A;  3AXZ A;  4JWH A;  2EGW A;  4CNE A;  4YQI A;  1V6Z A;  4X3M A;  4H3Z A;  3OIN A;  3KNU A;  1OY5 A;  3DCM X;  1TO0 A;  3L8U A;  4CND A;  4MCB A;  1UAJ A;  4YQK A;  2YY8 A;  1VHK A;  4YQR A;  4E8B A;  4YQD A;  3BBE A;  4YQ9 A;  3NK7 A;  2QMM A;  4CNG A;  3BBD A;  3AIA A;  1O6D A;  5GM8 A;  4YVG A;  2HA8 A;  3ILK A;  4J3C A;  4YQL A;  1NS5 A;  1V2X A;  4YPW A;  2O3A A;  4YPX A;  4FAK A;  3IC6 A;  3BBH A;  4YQ6 A;  1VHY A;  4PZK A;  4JWJ A;  3O7B A;  4YQO A;  4YVI A;  3OII A;  1IPA A;  4YVH A;  5D9F A;  1P9P A;  1NXZ A;  1UAL A;  4JAL A;  4YQN A;  4YPY A;  2V3J A;  1X7O A;  2QWV A;  4KDZ A;  4YQG A;  4CNF A;  3AI9 X;  4YQ1 A;  2V3K A;  3KY7 A;  3QUV A;  4YQ7 A;  4YQ3 A;  4L69 A;  4YVJ A;  3ONP A;  4JWF A;  1Z85 A;  3KTY A;  4XBO A;  5CO4 A;  4YQA A;  3OIJ A; 
#chains in the Genus database with same CATH homology
 3IEF A;  4YQB A;  1X7P A;  4YQ5 A;  4YQC A;  2I6D A;  1K3R A;  4RG1 A;  1MXI A;  4IG6 A;  4X3L A;  4FMW A;  4YQQ A;  4YQ0 A;  4MCD A;  4H3Y A;  4YQ8 A;  4MCC A;  5GMC A;  4YQ4 A;  1UAK A;  2Z0Y A;  4JAK A;  4YQS A;  1UAM A;  1GZ0 A;  3NK6 A;  4YQ2 A;  4YQP A;  4YQT A;  3N4K A;  3GYQ A;  3KW2 A;  4YVK A;  3E5Y A;  1VH0 A;  4KGN A;  4YQJ A;  1ZJR A;  3N4J A;  4JWG A;  4YPZ A;  2CX8 A;  5FAI A;  5GMB A;  1J85 A;  2EGV A;  3AXZ A;  4JWH A;  2EGW A;  4CNE A;  4YQI A;  1V6Z A;  4X3M A;  4H3Z A;  3OIN A;  3KNU A;  1OY5 A;  3DCM X;  1TO0 A;  3L8U A;  4CND A;  4MCB A;  1UAJ A;  4YQK A;  2YY8 A;  1VHK A;  4YQR A;  4E8B A;  4YQD A;  3BBE A;  4YQ9 A;  3NK7 A;  2QMM A;  4CNG A;  3BBD A;  3AIA A;  1O6D A;  5GM8 A;  4YVG A;  2HA8 A;  3ILK A;  4J3C A;  4YQL A;  1NS5 A;  1V2X A;  4YPW A;  2O3A A;  4YPX A;  4FAK A;  3IC6 A;  3BBH A;  4YQ6 A;  1VHY A;  4PZK A;  4JWJ A;  3O7B A;  4YQO A;  4YVI A;  3OII A;  1IPA A;  4YVH A;  5D9F A;  1P9P A;  1NXZ A;  1UAL A;  4JAL A;  4YQN A;  4YPY A;  2V3J A;  1X7O A;  2QWV A;  4KDZ A;  4YQG A;  4CNF A;  3AI9 X;  4YQ1 A;  2V3K A;  3KY7 A;  3QUV A;  4YQ7 A;  4YQ3 A;  4L69 A;  4YVJ A;  3ONP A;  4JWF A;  1Z85 A;  3KTY A;  4XBO A;  5CO4 A;  4YQA A;  3OIJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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