3OL0A

Crystal structure of monofoil-4p homo-trimer: de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
43
structure length
43
Chain Sequence
HHHPVLLKSTETGQYLRINPDGTVDGTRDRSDPHIQFQISPEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
pubmed doi rcsb
molecule keywords de novo designed monomer trefoil-fold sub-domain which forms
molecule tags De novo protein
source organism Synthetic construct
total genus 5
structure length 43
sequence length 43
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-08-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.260 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 3ol0A00
3OL0A
chains in the Genus database with same CATH superfamily
2SGQI 2FNFX 3D00A 1LR8A 1X74A 1LR7A 4WP4A 2ROWA 1PTRA 1HEVA 2VRWB 3HH2C 3CXLA 2OD1A 2RIJA 2A20A 2UZ3A 3OXGA 2DKVA 2KCXA 1MJAA 1M8CA 2JXDA 1H0ZA 1N13A 5E3PA 2F3CI 1BMOA 3TO7A 2OVOA 1UUCA 2DIPA 1S20A 2NU3I 2W0TA 3QWPA 5FUYA 2J9RA 5JHWC 1ULNA 3R5CA 4MPIA 4E1RA 1TBRR 4L9MA 2GIVA 2NU0I 2WVJA 2GKRI 2SGDI 2ELIA 1MJ9A 1Y1CA 2UVOA 3RU0A 2JW6A 2OU2A 2E73A 1V1IA 1FAQA 1TURA 1CE3A 1OYVI 1YU6C 2YUUA 1OMUA 4HGUA 2Y0MA 1XX6A 3UEJA 2ORWA 2V1CA 1TBNA 1CT4I 1UHAA 1BUSA 3FSXA 1P9ZA 1VDDA 3OXLA 1SGQI 1XBTA 1IY5A 3OXFA 1W3SA 2N52A 2NU4I 4GI3C 3QAHA 3R5BA 1WGCA 2ORVA 2X3TA 4OVOA 5E3QA 2KMOA 5HI7A 9WGAA 2CWFA 5HQ8A 2ERWA 1IY6A 1NXUA 1TIHA 2SGPI 3OL0A 1V1HA 1R79A 3TOBA 2JA1A 2N1AB 1PPFI 3UFFA 2QQDA 1AN1I 3TO9A 3UGLA 1PJUA 2E5RA 1CGJI 1Y1BA 4UXIA 2CWHA 4SGBI 1YTPA 3VDUA 2JZMA 1DS2I 1OVOA 1UVFA 1X4SA 7WGAA 3QTLD 2NU1I 5EX3A 1WTJA 1HPTA 5FUXA 1WKXA 1ULKA 1TBOA 2GKTI 2QQ0A 1CT0I 3UOEA 1TOTA 5EX0A 3SGBI 1IW4A 1ULMA 2J87A 3KY9A 5FUWA 2YQPA 4UXHA 4AMLA 1SGRI 2B0UC 3B4VC 1U5KA 1UVGA 2V53A 1CHOI 3TOAA 1MJBA 2SGEI 1XA6A 1TGSI 2M5XA 2OZUA 4A24A 1FARA 5CCMA 1TUSA 3E59A 2B8TA 2QQEA 1CT2I 4FKDA 1NUBA 1CGII 3UGDA 2LUYA 3R5DA 5J8FA 1K7UA 4JCVE 2DB6A 1CSOI 2BUSA 1SGPI 2V1CC 3SEKC 1KBFA 2GVIA 3GOXA 1RFHA 1M8BA 3MEKA 2ODDA 1R0RI 1DS3I 2KMQA 1Q9BA 2ENNA 1SGEI 2CJSC 2K9HA 2WCYA 2L8EA 3PDNA 4UXJA 4B6DA 2N17A 2N71A 2ENZA 1FY7A 1SGYI 3E2IA 1PTQA 2JYYA 5CCLA 4DNCA 1KMAA 1SGDI 1TBQR 2LB7A 1Y8FA 1Z7KB 2CWGA 2KMPA 2P6AC 1HJAI 2KMRA 1HDLA 2X52A 3BJIA 1LR9A 2SGFI 2ARPF 2LEOA 5E3RA 2QPOA 2L7XA 2WGCA 3R5AA 2PQ8A 2RC4A 3SGQI 1MT1A 3TJQA 1K7VA 2GKVA 3VDPA 2NU2I 5J8CA 3FC3A 3FSYA 5FUVA 1K7TA 4E1PA 3UEYA 1PCEA 1Z2IA 1FYBA 1OMTA 1KBEA 5DAEA 1SGNI 1W4RA 1WGTA 3OVOA 2XRCA 3VE5A 3TO6A 3UGIA 1P9GA 2QQCA
chains in the Genus database with same CATH topology
2SGQI 2FNFX 3D00A 1LR8A 1X74A 1LR7A 2ROWA 1PTRA 2VRWB 3HH2C 3CXLA 2OD1A 2UZ3A 2A20A 3OXGA 2KCXA 1M8CA 2JXDA 1H0ZA 1N13A 2F3CI 1BMOA 2OVOA 1UUCA 2DIPA 2NU3I 3QWPA 2W0TA 5FUYA 2J9RA 5JHWC 4E1RA 1TBRR 4L9MA 2NU0I 2WVJA 2GKRI 2SGDI 2ELIA 1Y1CA 3RU0A 2JW6A 2E73A 1V1IA 1FAQA 1TURA 1CE3A 1OYVI 1YU6C 2YUUA 1OMUA 4HGUA 3UEJA 1XX6A 2ORWA 2V1CA 1TBNA 1CT4I 1BUSA 1VDDA 3OXLA 1SGQI 1XBTA 1IY5A 3OXFA 1W3SA 2N52A 2NU4I 4GI3C 2ORVA 4OVOA 5HQ8A 5HI7A 1IY6A 2KMOA 2ERWA 1TIHA 2SGPI 3OL0A 1V1HA 1R79A 2JA1A 2N1AB 1PPFI 3UFFA 2QQDA 1AN1I 3UGLA 1PJUA 2E5RA 1CGJI 4UXIA 4SGBI 1YTPA 3VDUA 2JZMA 1DS2I 1OVOA 1UVFA 1X4SA 3QTLD 2NU1I 5EX3A 1HPTA 5FUXA 2QQ0A 1TBOA 2GKTI 1CT0I 1TOTA 5EX0A 3SGBI 1IW4A 2J87A 3KY9A 5FUWA 2YQPA 4UXHA 1SGRI 2B0UC 3B4VC 1U5KA 1UVGA 2V53A 1CHOI 4A24A 2SGEI 1XA6A 1TGSI 2M5XA 5CCMA 1FARA 1TUSA 3E59A 2B8TA 2QQEA 1CT2I 4FKDA 1NUBA 1CGII 3UGDA 2LUYA 4JCVE 2DB6A 1CSOI 2BUSA 1SGPI 2V1CC 3SEKC 1KBFA 2GVIA 3GOXA 1RFHA 1M8BA 3MEKA 2ODDA 1R0RI 1DS3I 2KMQA 2ENNA 1SGEI 2CJSC 2K9HA 2WCYA 2L8EA 3PDNA 4UXJA 4B6DA 2N17A 2N71A 2ENZA 1SGYI 3E2IA 1PTQA 2JYYA 5CCLA 1KMAA 1SGDI 1TBQR 1Y8FA 1Z7KB 2KMPA 1HDLA 2P6AC 1HJAI 2KMRA 3BJIA 1LR9A 2SGFI 2ARPF 2LEOA 2QPOA 2L7XA 3SGQI 1MT1A 3TJQA 2GKVA 3VDPA 2NU2I 3FC3A 5FUVA 4E1PA 3UEYA 1PCEA 1FYBA 1OMTA 1KBEA 5DAEA 1SGNI 1W4RA 3OVOA 2XRCA 3VE5A 3UGIA 1Y1BA 2QQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OL0 A; 
#chains in the Genus database with same CATH topology
 2SGQ I;  2FNF X;  3D00 A;  1LR8 A;  1X74 A;  1LR7 A;  4WP4 A;  2ROW A;  1PTR A;  1HEV A;  2VRW B;  3HH2 C;  3CXL A;  2OD1 A;  2RIJ A;  2A20 A;  2UZ3 A;  3OXG A;  2DKV A;  2KCX A;  1MJA A;  1M8C A;  2JXD A;  1H0Z A;  1N13 A;  5E3P A;  2F3C I;  1BMO A;  3TO7 A;  2OVO A;  1UUC A;  2DIP A;  1S20 A;  2NU3 I;  2W0T A;  3QWP A;  5FUY A;  2J9R A;  5JHW C;  1ULN A;  3R5C A;  4MPI A;  4E1R A;  1TBR R;  4L9M A;  2GIV A;  2NU0 I;  2WVJ A;  2GKR I;  2SGD I;  2ELI A;  1MJ9 A;  1Y1C A;  2UVO A;  3RU0 A;  2JW6 A;  2OU2 A;  2E73 A;  1V1I A;  1FAQ A;  1TUR A;  1CE3 A;  1OYV I;  1YU6 C;  2YUU A;  1OMU A;  4HGU A;  2Y0M A;  1XX6 A;  3UEJ A;  2ORW A;  2V1C A;  1TBN A;  1CT4 I;  1UHA A;  1BUS A;  3FSX A;  1P9Z A;  1VDD A;  3OXL A;  1SGQ I;  1XBT A;  1IY5 A;  3OXF A;  1W3S A;  2N52 A;  2NU4 I;  4GI3 C;  3QAH A;  3R5B A;  1WGC A;  2ORV A;  2X3T A;  4OVO A;  5E3Q A;  2KMO A;  5HI7 A;  9WGA A;  2CWF A;  5HQ8 A;  2ERW A;  1IY6 A;  1NXU A;  1TIH A;  2SGP I;  3OL0 A;  1V1H A;  1R79 A;  3TOB A;  2JA1 A;  2N1A B;  1PPF I;  3UFF A;  2QQD A;  1AN1 I;  3TO9 A;  3UGL A;  1PJU A;  2E5R A;  1CGJ I;  1Y1B A;  4UXI A;  2CWH A;  4SGB I;  1YTP A;  3VDU A;  2JZM A;  1DS2 I;  1OVO A;  1UVF A;  1X4S A;  7WGA A;  3QTL D;  2NU1 I;  5EX3 A;  1WTJ A;  1HPT A;  5FUX A;  1WKX A;  1ULK A;  1TBO A;  2GKT I;  2QQ0 A;  1CT0 I;  3UOE A;  1TOT A;  5EX0 A;  3SGB I;  1IW4 A;  1ULM A;  2J87 A;  3KY9 A;  5FUW A;  2YQP A;  4UXH A;  4AML A;  1SGR I;  2B0U C;  3B4V C;  1U5K A;  1UVG A;  2V53 A;  1CHO I;  3TOA A;  1MJB A;  2SGE I;  1XA6 A;  1TGS I;  2M5X A;  2OZU A;  4A24 A;  1FAR A;  5CCM A;  1TUS A;  3E59 A;  2B8T A;  2QQE A;  1CT2 I;  4FKD A;  1NUB A;  1CGI I;  3UGD A;  2LUY A;  3R5D A;  5J8F A;  1K7U A;  4JCV E;  2DB6 A;  1CSO I;  2BUS A;  1SGP I;  2V1C C;  3SEK C;  1KBF A;  2GVI A;  3GOX A;  1RFH A;  1M8B A;  3MEK A;  2ODD A;  1R0R I;  1DS3 I;  2KMQ A;  1Q9B A;  2ENN A;  1SGE I;  2CJS C;  2K9H A;  2WCY A;  2L8E A;  3PDN A;  4UXJ A;  4B6D A;  2N17 A;  2N71 A;  2ENZ A;  1FY7 A;  1SGY I;  3E2I A;  1PTQ A;  2JYY A;  5CCL A;  4DNC A;  1KMA A;  1SGD I;  1TBQ R;  2LB7 A;  1Y8F A;  1Z7K B;  2CWG A;  2KMP A;  2P6A C;  1HJA I;  2KMR A;  1HDL A;  2X52 A;  3BJI A;  1LR9 A;  2SGF I;  2ARP F;  2LEO A;  5E3R A;  2QPO A;  2L7X A;  2WGC A;  3R5A A;  2PQ8 A;  2RC4 A;  3SGQ I;  1MT1 A;  3TJQ A;  1K7V A;  2GKV A;  3VDP A;  2NU2 I;  5J8C A;  3FC3 A;  3FSY A;  5FUV A;  1K7T A;  4E1P A;  3UEY A;  1PCE A;  1Z2I A;  1FYB A;  1OMT A;  1KBE A;  5DAE A;  1SGN I;  1W4R A;  1WGT A;  3OVO A;  2XRC A;  3VE5 A;  3TO6 A;  3UGI A;  1P9G A;  2QQC A; 
#chains in the Genus database with same CATH homology
 2SGQ I;  2FNF X;  3D00 A;  1LR8 A;  1X74 A;  1LR7 A;  2ROW A;  1PTR A;  2VRW B;  3HH2 C;  3CXL A;  2OD1 A;  2UZ3 A;  2A20 A;  3OXG A;  2KCX A;  1M8C A;  2JXD A;  1H0Z A;  1N13 A;  2F3C I;  1BMO A;  2OVO A;  1UUC A;  2DIP A;  2NU3 I;  3QWP A;  2W0T A;  5FUY A;  2J9R A;  5JHW C;  4E1R A;  1TBR R;  4L9M A;  2NU0 I;  2WVJ A;  2GKR I;  2SGD I;  2ELI A;  1Y1C A;  3RU0 A;  2JW6 A;  2E73 A;  1V1I A;  1FAQ A;  1TUR A;  1CE3 A;  1OYV I;  1YU6 C;  2YUU A;  1OMU A;  4HGU A;  3UEJ A;  1XX6 A;  2ORW A;  2V1C A;  1TBN A;  1CT4 I;  1BUS A;  1VDD A;  3OXL A;  1SGQ I;  1XBT A;  1IY5 A;  3OXF A;  1W3S A;  2N52 A;  2NU4 I;  4GI3 C;  2ORV A;  4OVO A;  5HQ8 A;  5HI7 A;  1IY6 A;  2KMO A;  2ERW A;  1TIH A;  2SGP I;  3OL0 A;  1V1H A;  1R79 A;  2JA1 A;  2N1A B;  1PPF I;  3UFF A;  2QQD A;  1AN1 I;  3UGL A;  1PJU A;  2E5R A;  1CGJ I;  4UXI A;  4SGB I;  1YTP A;  3VDU A;  2JZM A;  1DS2 I;  1OVO A;  1UVF A;  1X4S A;  3QTL D;  2NU1 I;  5EX3 A;  1HPT A;  5FUX A;  2QQ0 A;  1TBO A;  2GKT I;  1CT0 I;  1TOT A;  5EX0 A;  3SGB I;  1IW4 A;  2J87 A;  3KY9 A;  5FUW A;  2YQP A;  4UXH A;  1SGR I;  2B0U C;  3B4V C;  1U5K A;  1UVG A;  2V53 A;  1CHO I;  4A24 A;  2SGE I;  1XA6 A;  1TGS I;  2M5X A;  5CCM A;  1FAR A;  1TUS A;  3E59 A;  2B8T A;  2QQE A;  1CT2 I;  4FKD A;  1NUB A;  1CGI I;  3UGD A;  2LUY A;  4JCV E;  2DB6 A;  1CSO I;  2BUS A;  1SGP I;  2V1C C;  3SEK C;  1KBF A;  2GVI A;  3GOX A;  1RFH A;  1M8B A;  3MEK A;  2ODD A;  1R0R I;  1DS3 I;  2KMQ A;  2ENN A;  1SGE I;  2CJS C;  2K9H A;  2WCY A;  2L8E A;  3PDN A;  4UXJ A;  4B6D A;  2N17 A;  2N71 A;  2ENZ A;  1SGY I;  3E2I A;  1PTQ A;  2JYY A;  5CCL A;  1KMA A;  1SGD I;  1TBQ R;  1Y8F A;  1Z7K B;  2KMP A;  1HDL A;  2P6A C;  1HJA I;  2KMR A;  3BJI A;  1LR9 A;  2SGF I;  2ARP F;  2LEO A;  2QPO A;  2L7X A;  3SGQ I;  1MT1 A;  3TJQ A;  2GKV A;  3VDP A;  2NU2 I;  3FC3 A;  5FUV A;  4E1P A;  3UEY A;  1PCE A;  1FYB A;  1OMT A;  1KBE A;  5DAE A;  1SGN I;  1W4R A;  3OVO A;  2XRC A;  3VE5 A;  3UGI A;  1Y1B A;  2QQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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