3ORGA

Crystal structure of a eukaryotic clc transporter
Total Genus 170
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
623
structure length
534
Chain Sequence
SLMYLLRLVCFLTLLGVTAALFIFAVDLAVHGLEELRMKISRLAGRFAGYILYVVSGVALCLLSTFWCAVLSTEAEGSGLPQMKSILSGFYDKMRSALELRVLFAKALGLICAIGGGLPVGWEGPNVHIACIIAHQFYRLGVFKELCTDRALRLQTLAAACAVGLASSFGAPLGGVLYSIETIASFYLVQAFWKGVLSALSGAIVYELDVSRTQTLLYAILGALMGVLGALFIRCVRSIYELRMRHYPGTNRYFLVGVVALFASALQYPFPRATINDLFKAVTELILMPIIKFILVALSIGLPLPAGVFVPSFLIGAGFGRLYGELMRVVFGNAIVPGSYAVVGAAAFTAGVTRALSCAVIIFEVTGQIRHLVPVLISVLLAVIVGNAFNRSLYETLVLMKHLPYMPILRRDRSPEMTAREIMHPIEGEPHLFPDSEPQHIKGILEKFPNRLVFPVIDANGYLLGAISRKEIVDRLQHVVVPCDVSPIVVTSYSLVRQLHFLFVMLMPSMIYVTERGKLVGIVEREDVAYGYSN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
pubmed doi rcsb
molecule keywords CmCLC
molecule tags Transport protein
source organism Cyanidioschyzon merolae
total genus 170
structure length 534
sequence length 623
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-09-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 3orgA01
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 3orgA02
4GQVA 3LQNA 3OCOA 2EXWA 2HLFA 3EJZA 3PC2A 4L28A 2EMQA 1OTUA 2UV6A 4FRYA 4ESYA 4L0DA 4GQWA 2HTLA 3Q17A 4KK5A 4MQXA 3FHMA 2R9HA 4ESYB 2OOXE 2QREE 2RIFA 3FV6A 5LXQA 1KPLA 2UV7A 4KK8A 2QRCE 4KKAA 3TDHC 2FEDA 4P1GA 2NYCA 2QRDE 2HT4A 3HF7A 5K24C 2OOYE 2QH1A 4FXSA 4DQWA 2O16A 2YVYA 3ORGA 4FG6A 4KJPA 4KJQA 2UV4A 2FECA 3KPDA 2QR1E 4IY3A 2EF7A 4HG0A 3FNAA 2HT3A 2EXYA 2RC3A 2PFIA 3I8NA 4ENEA 3L2BA 4KKBA 3EJYA 1PVMA 4KK9A 3LV9A 3TE5C 3KPCA 4COOA 5MMZA 3FWRA 4KJWA 3ND0A 4O9KA 3OCMA 4UUUA 2D4ZA 2RIHA 4FTPA 3KXRA 2YVZA 3SL7A 4KK6A 3FWSA 2HTKA 1OTSA 3NMOA 3GBYA 4KKLA 4GQYA 3PC4A 4IY0A 1YAVA 2H2PA 2YZIA 3LHHA 2H2SA 4NOCA 2FEEA 1KPKA 2EZ0A 2OUXA 1OTTA 4IYSA 2NYEA 4IY2A 3PC3A 2YZQA 1XKFA 3T4NC 5HD8A 5IIPA 4PCUA 1PBJA 1Y5HA 5KS7A 3KPBA 3L31A 2UV5A 3DETA 4P1OA 2HT2A 3OI8A 3K6EA 3DDJA 4KKCA 3LFZA 2YVXA 2P9MA 4L3VA 4L27A 5K25C 1O50A 2ZY9A 3K2VA 4IY4A 3KH5A 4LOUA 5K22B 5K23C 2QLVC
chains in the Genus database with same CATH superfamily
4GQVA 3LQNA 3OCOA 2EXWA 2HLFA 3EJZA 3PC2A 4L28A 2EMQA 1OTUA 2UV6A 4FRYA 4ESYA 4L0DA 4GQWA 2HTLA 3Q17A 4KK5A 4MQXA 3FHMA 2R9HA 4ESYB 2OOXE 2QREE 2RIFA 3FV6A 5LXQA 1KPLA 2UV7A 4KK8A 2QRCE 4KKAA 3TDHC 2FEDA 4P1GA 2NYCA 2QRDE 2HT4A 3HF7A 5K24C 2OOYE 2QH1A 4FXSA 4DQWA 2O16A 2YVYA 3ORGA 4FG6A 2J9LA 4KJPA 4KJQA 2UV4A 2FECA 3KPDA 2QR1E 2JA3A 4IY3A 2EF7A 4HG0A 3FNAA 2HT3A 2EXYA 2RC3A 2PFIA 3I8NA 4ENEA 3L2BA 4KKBA 3EJYA 1PVMA 4KK9A 3LV9A 3TE5C 3KPCA 4COOA 5MMZA 3FWRA 4KJWA 3ND0A 4O9KA 3OCMA 4UUUA 2D4ZA 2RIHA 4FTPA 3KXRA 2YVZA 3SL7A 4KK6A 3FWSA 2HTKA 1OTSA 3NMOA 3GBYA 4KKLA 4GQYA 3PC4A 4IY0A 1YAVA 2H2PA 2YZIA 3LHHA 2H2SA 4NOCA 2FEEA 1KPKA 2EZ0A 2OUXA 1OTTA 4IYSA 2NYEA 4IY2A 3PC3A 2YZQA 1XKFA 3T4NC 5HD8A 5IIPA 4PCUA 1PBJA 1Y5HA 5KS7A 3KPBA 3L31A 2UV5A 3DETA 4P1OA 2HT2A 3OI8A 3K6EA 3DDJA 4KKCA 3LFZA 2YVXA 2P9MA 4L3VA 4L27A 5K25C 1O50A 2ZY9A 3K2VA 4IY4A 3KH5A 4LOUA 5K22B 5K23C 2QLVC
chains in the Genus database with same CATH topology
4GQVA 3LQNA 3OCOA 2EXWA 2HLFA 3EJZA 3PC2A 4L28A 2EMQA 1OTUA 2UV6A 4FRYA 4ESYA 4L0DA 4GQWA 2HTLA 3Q17A 4KK5A 4MQXA 3FHMA 2R9HA 4ESYB 2OOXE 2QREE 2RIFA 3FV6A 5LXQA 1KPLA 2UV7A 4KK8A 2QRCE 4KKAA 3TDHC 2FEDA 4P1GA 2NYCA 2QRDE 2HT4A 3HF7A 5K24C 2OOYE 2QH1A 4FXSA 4DQWA 2O16A 2YVYA 3ORGA 4FG6A 2J9LA 4KJPA 4KJQA 2UV4A 2FECA 3KPDA 2QR1E 2JA3A 4IY3A 2EF7A 4HG0A 3FNAA 2HT3A 2EXYA 2RC3A 2PFIA 3I8NA 4ENEA 3L2BA 4KKBA 3EJYA 1PVMA 4KK9A 3LV9A 3TE5C 3KPCA 4COOA 5MMZA 3FWRA 4KJWA 3ND0A 4O9KA 3OCMA 4UUUA 2D4ZA 2RIHA 4FTPA 3KXRA 2YVZA 3SL7A 4KK6A 3FWSA 2HTKA 1OTSA 3NMOA 3GBYA 4KKLA 4GQYA 3PC4A 4IY0A 1YAVA 2H2PA 2YZIA 3LHHA 2H2SA 4NOCA 2FEEA 1KPKA 2EZ0A 2OUXA 1OTTA 4IYSA 2NYEA 4IY2A 3PC3A 2YZQA 1XKFA 3T4NC 5HD8A 5IIPA 4PCUA 1PBJA 1Y5HA 5KS7A 3KPBA 3L31A 2UV5A 3DETA 4P1OA 2HT2A 3OI8A 3K6EA 3DDJA 4KKCA 3LFZA 2YVXA 2P9MA 4L3VA 4L27A 5K25C 1O50A 2ZY9A 3K2VA 4IY4A 3KH5A 4LOUA 5K22B 5K23C 2QLVC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GQV A;  3LQN A;  3OCO A;  2EXW A;  2HLF A;  3EJZ A;  3PC2 A;  4L28 A;  2EMQ A;  1OTU A;  2UV6 A;  4FRY A;  4ESY A;  4L0D A;  4GQW A;  2HTL A;  3Q17 A;  4KK5 A;  4MQX A;  3FHM A;  2R9H A;  4ESY B;  2OOX E;  2QRE E;  2RIF A;  3FV6 A;  5LXQ A;  1KPL A;  2UV7 A;  4KK8 A;  2QRC E;  4KKA A;  3TDH C;  2FED A;  4P1G A;  2NYC A;  2QRD E;  2HT4 A;  3HF7 A;  5K24 C;  2OOY E;  2QH1 A;  4FXS A;  4DQW A;  2O16 A;  2YVY A;  3ORG A;  4FG6 A;  4KJP A;  4KJQ A;  2UV4 A;  2FEC A;  3KPD A;  2QR1 E;  4IY3 A;  2EF7 A;  4HG0 A;  3FNA A;  2HT3 A;  2EXY A;  2RC3 A;  2PFI A;  3I8N A;  4ENE A;  3L2B A;  4KKB A;  3EJY A;  1PVM A;  4KK9 A;  3LV9 A;  3TE5 C;  3KPC A;  4COO A;  5MMZ A;  3FWR A;  4KJW A;  3ND0 A;  4O9K A;  3OCM A;  4UUU A;  2D4Z A;  2RIH A;  4FTP A;  3KXR A;  2YVZ A;  3SL7 A;  4KK6 A;  3FWS A;  2HTK A;  1OTS A;  3NMO A;  3GBY A;  4KKL A;  4GQY A;  3PC4 A;  4IY0 A;  1YAV A;  2H2P A;  2YZI A;  3LHH A;  2H2S A;  4NOC A;  2FEE A;  1KPK A;  2EZ0 A;  2OUX A;  1OTT A;  4IYS A;  2NYE A;  4IY2 A;  3PC3 A;  2YZQ A;  1XKF A;  3T4N C;  5HD8 A;  5IIP A;  4PCU A;  1PBJ A;  1Y5H A;  5KS7 A;  3KPB A;  3L31 A;  2UV5 A;  3DET A;  4P1O A;  2HT2 A;  3OI8 A;  3K6E A;  3DDJ A;  4KKC A;  3LFZ A;  2YVX A;  2P9M A;  4L3V A;  4L27 A;  5K25 C;  1O50 A;  2ZY9 A;  3K2V A;  4IY4 A;  3KH5 A;  4LOU A;  5K22 B;  5K23 C;  2QLV C; 
#chains in the Genus database with same CATH topology
 4GQV A;  3LQN A;  3OCO A;  2EXW A;  2HLF A;  3EJZ A;  3PC2 A;  4L28 A;  2EMQ A;  1OTU A;  2UV6 A;  4FRY A;  4ESY A;  4L0D A;  4GQW A;  2HTL A;  3Q17 A;  4KK5 A;  4MQX A;  3FHM A;  2R9H A;  4ESY B;  2OOX E;  2QRE E;  2RIF A;  3FV6 A;  5LXQ A;  1KPL A;  2UV7 A;  4KK8 A;  2QRC E;  4KKA A;  3TDH C;  2FED A;  4P1G A;  2NYC A;  2QRD E;  2HT4 A;  3HF7 A;  5K24 C;  2OOY E;  2QH1 A;  4FXS A;  4DQW A;  2O16 A;  2YVY A;  3ORG A;  4FG6 A;  2J9L A;  4KJP A;  4KJQ A;  2UV4 A;  2FEC A;  3KPD A;  2QR1 E;  2JA3 A;  4IY3 A;  2EF7 A;  4HG0 A;  3FNA A;  2HT3 A;  2EXY A;  2RC3 A;  2PFI A;  3I8N A;  4ENE A;  3L2B A;  4KKB A;  3EJY A;  1PVM A;  4KK9 A;  3LV9 A;  3TE5 C;  3KPC A;  4COO A;  5MMZ A;  3FWR A;  4KJW A;  3ND0 A;  4O9K A;  3OCM A;  4UUU A;  2D4Z A;  2RIH A;  4FTP A;  3KXR A;  2YVZ A;  3SL7 A;  4KK6 A;  3FWS A;  2HTK A;  1OTS A;  3NMO A;  3GBY A;  4KKL A;  4GQY A;  3PC4 A;  4IY0 A;  1YAV A;  2H2P A;  2YZI A;  3LHH A;  2H2S A;  4NOC A;  2FEE A;  1KPK A;  2EZ0 A;  2OUX A;  1OTT A;  4IYS A;  2NYE A;  4IY2 A;  3PC3 A;  2YZQ A;  1XKF A;  3T4N C;  5HD8 A;  5IIP A;  4PCU A;  1PBJ A;  1Y5H A;  5KS7 A;  3KPB A;  3L31 A;  2UV5 A;  3DET A;  4P1O A;  2HT2 A;  3OI8 A;  3K6E A;  3DDJ A;  4KKC A;  3LFZ A;  2YVX A;  2P9M A;  4L3V A;  4L27 A;  5K25 C;  1O50 A;  2ZY9 A;  3K2V A;  4IY4 A;  3KH5 A;  4LOU A;  5K22 B;  5K23 C;  2QLV C; 
#chains in the Genus database with same CATH homology
 4GQV A;  3LQN A;  3OCO A;  2EXW A;  2HLF A;  3EJZ A;  3PC2 A;  4L28 A;  2EMQ A;  1OTU A;  2UV6 A;  4FRY A;  4ESY A;  4L0D A;  4GQW A;  2HTL A;  3Q17 A;  4KK5 A;  4MQX A;  3FHM A;  2R9H A;  4ESY B;  2OOX E;  2QRE E;  2RIF A;  3FV6 A;  5LXQ A;  1KPL A;  2UV7 A;  4KK8 A;  2QRC E;  4KKA A;  3TDH C;  2FED A;  4P1G A;  2NYC A;  2QRD E;  2HT4 A;  3HF7 A;  5K24 C;  2OOY E;  2QH1 A;  4FXS A;  4DQW A;  2O16 A;  2YVY A;  3ORG A;  4FG6 A;  2J9L A;  4KJP A;  4KJQ A;  2UV4 A;  2FEC A;  3KPD A;  2QR1 E;  2JA3 A;  4IY3 A;  2EF7 A;  4HG0 A;  3FNA A;  2HT3 A;  2EXY A;  2RC3 A;  2PFI A;  3I8N A;  4ENE A;  3L2B A;  4KKB A;  3EJY A;  1PVM A;  4KK9 A;  3LV9 A;  3TE5 C;  3KPC A;  4COO A;  5MMZ A;  3FWR A;  4KJW A;  3ND0 A;  4O9K A;  3OCM A;  4UUU A;  2D4Z A;  2RIH A;  4FTP A;  3KXR A;  2YVZ A;  3SL7 A;  4KK6 A;  3FWS A;  2HTK A;  1OTS A;  3NMO A;  3GBY A;  4KKL A;  4GQY A;  3PC4 A;  4IY0 A;  1YAV A;  2H2P A;  2YZI A;  3LHH A;  2H2S A;  4NOC A;  2FEE A;  1KPK A;  2EZ0 A;  2OUX A;  1OTT A;  4IYS A;  2NYE A;  4IY2 A;  3PC3 A;  2YZQ A;  1XKF A;  3T4N C;  5HD8 A;  5IIP A;  4PCU A;  1PBJ A;  1Y5H A;  5KS7 A;  3KPB A;  3L31 A;  2UV5 A;  3DET A;  4P1O A;  2HT2 A;  3OI8 A;  3K6E A;  3DDJ A;  4KKC A;  3LFZ A;  2YVX A;  2P9M A;  4L3V A;  4L27 A;  5K25 C;  1O50 A;  2ZY9 A;  3K2V A;  4IY4 A;  3KH5 A;  4LOU A;  5K22 B;  5K23 C;  2QLV C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...